Nuno A. Silva - Publications

Affiliations: 
ICVS - Life and Health Sciences Research Institute 
Area:
Spinal Cord Injury, Pharmacology, Stem Cells, Neuroprotection, Neuroregeneration

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Assunção-Silva RC, Pinho A, Cibrão JR, Pereira IM, Monteiro S, Silva NA, Campos J, Rebelo AL, Schlosser G, Pinto L, Pandit A, Salgado AJ. Adipose tissue derived stem cell secretome induces motor and histological gains after complete spinal cord injury in and mice. Journal of Tissue Engineering. 15: 20417314231203824. PMID 38343771 DOI: 10.1177/20417314231203824  0.77
2023 Sousa CS, Lima R, Cibrão JR, Gomes ED, Fernandes LS, Pinho TS, Silva D, Campos J, Salgado AJ, Silva NA. Pre-Clinical Assessment of Roflumilast Therapy in a Thoracic Model of Spinal Cord Injury. Pharmaceutics. 15. PMID 37242797 DOI: 10.3390/pharmaceutics15051556  0.837
2023 Pinho AG, Monteiro A, Fernandes S, de Sousa N, Salgado AJ, Silva NA, Monteiro S. The Central Nervous System Source Modulates Microglia Function and Morphology In Vitro. International Journal of Molecular Sciences. 24. PMID 37175391 DOI: 10.3390/ijms24097685  0.708
2022 de Sousa N, Robledo D, González-Llera L, Pinho AG, Santos DJ, Monteiro S, Campos J, Cibrão JR, Silva NA, Sánchez L, Salgado AJ, Barreiro-Iglesias A. Spinal cord RNA-seq data after a baclofen treatment in mice with a spinal cord injury. Data in Brief. 46: 108809. PMID 36569535 DOI: 10.1016/j.dib.2022.108809  0.731
2022 Lima R, Monteiro A, Salgado AJ, Monteiro S, Silva NA. Pathophysiology and Therapeutic Approaches for Spinal Cord Injury. International Journal of Molecular Sciences. 23. PMID 36430308 DOI: 10.3390/ijms232213833  0.817
2022 de Sousa N, Pinho AG, Monteiro S, Liberato V, Santos DJ, Campos J, Cibrão JR, Silva NA, Barreiro-Iglesias A, Salgado AJ. Acute Baclofen administration promotes functional recovery after Spinal Cord Injury. The Spine Journal : Official Journal of the North American Spine Society. PMID 36155240 DOI: 10.1016/j.spinee.2022.09.007  0.748
2022 Fernandes A, Campos J, Silva D, Antunes S, Lima R, Coelho C, Marote A, Almeida H, Silva N, Salgado AJ. Effects of Stem Cell Secretome on Opioid Receptors and Neuroplasticity in Cerebral Organoids. Stem Cells and Development. PMID 36082997 DOI: 10.1089/scd.2022.0116  0.694
2022 Pinho AG, Cibrão JR, Lima R, Gomes ED, Serra SC, Lentilhas-Graça J, Ribeiro C, Lanceros-Mendez S, Teixeira FG, Monteiro S, Silva NA, Salgado AJ. Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury. Experimental Neurology. 351: 113989. PMID 35065953 DOI: 10.1016/j.expneurol.2022.113989  0.849
2021 Correia JS, Neves-Carvalho A, Mendes-Pinheiro B, Pires J, Teixeira FG, Lima R, Monteiro S, Silva NA, Soares-Cunha C, Serra SC, Duarte-Silva S, Teixeira-Castro A, Salgado AJ, Maciel P. Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3. Biomedicines. 9. PMID 34944570 DOI: 10.3390/biomedicines9121754  0.776
2021 Campos J, Silva NA, Salgado AJ. Nutritional interventions for spinal cord injury: preclinical efficacy and molecular mechanisms. Nutrition Reviews. PMID 34472615 DOI: 10.1093/nutrit/nuab068  0.74
2021 Lima R, Gomes ED, Cibrão JR, Rocha LA, Assunção-Silva RC, Rodrigues CS, Neves-Carvalho A, Monteiro S, Salgado AJ, Silva NA. Levetiracetam treatment leads to functional recovery after thoracic or cervical injuries of the spinal cord. Npj Regenerative Medicine. 6: 11. PMID 33654068 DOI: 10.1038/s41536-021-00121-7  0.842
2021 de Sousa N, Santos D, Monteiro S, Silva N, Barreiro-Iglesias A, Salgado AJ. Role of Baclofen in Modulating Spasticity and Neuroprotection in Spinal Cord Injury. Journal of Neurotrauma. PMID 33599153 DOI: 10.1089/neu.2020.7591  0.748
2020 Gomes ED, Ghosh B, Lima R, Goulão M, Moreira-Gomes T, Martins-Macedo J, Urban MW, Wright MC, Gimble JM, Sousa N, Silva NA, Lepore AC, Salgado AJ. Combination of a Gellan Gum-Based Hydrogel With Cell Therapy for the Treatment of Cervical Spinal Cord Injury. Frontiers in Bioengineering and Biotechnology. 8: 984. PMID 32984278 DOI: 10.3389/Fbioe.2020.00984  0.846
2020 Monteiro S, Pinho AG, Macieira M, Serre-Miranda C, Cibrão JR, Lima R, Soares-Cunha C, Vasconcelos NL, Lentilhas-Graça J, Duarte-Silva S, Miranda A, Correia-Neves M, Salgado AJ, Silva NA. Splenic sympathetic signaling contributes to acute neutrophil infiltration of the injured spinal cord. Journal of Neuroinflammation. 17: 282. PMID 32967684 DOI: 10.1186/s12974-020-01945-8  0.834
2020 Lima R, Monteiro S, Gomes ED, Vasconcelos NL, Assunção-Silva R, Morais M, Salgado AJ, Silva NA. Citalopram Administration Does Not Promote Function or Histological Recovery after Spinal Cord Injury. International Journal of Molecular Sciences. 21. PMID 32709070 DOI: 10.3390/Ijms21145062  0.836
2020 Rocha LA, Gomes ED, Afonso JL, Granja S, Baltazar F, Silva NA, Shoichet MS, Sousa RA, Learmonth DA, Salgado AJ. Evaluation of ASCs and HUVECs Co-cultures in 3D Biodegradable Hydrogels on Neurite Outgrowth and Vascular Organization. Frontiers in Cell and Developmental Biology. 8: 489. PMID 32612997 DOI: 10.3389/Fcell.2020.00489  0.787
2020 Pinho AG, Cibrão JR, Silva NA, Monteiro S, Salgado AJ. Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders. Pharmaceuticals (Basel, Switzerland). 13. PMID 32093352 DOI: 10.3390/Ph13020031  0.73
2020 Rocha LA, Silva D, Barata‐Antunes S, Cavaleiro H, Gomes ED, Silva NA, Salgado AJ. Cell and Tissue Instructive Materials for Central Nervous System Repair Advanced Functional Materials. 1909083. DOI: 10.1002/Adfm.201909083  0.671
2019 Pereira IM, Marote A, Salgado AJ, Silva NA. Filling the Gap: Neural Stem Cells as A Promising Therapy for Spinal Cord Injury. Pharmaceuticals (Basel, Switzerland). 12. PMID 31035689 DOI: 10.3390/Ph12020065  0.79
2019 Costa MM, Lima R, Melo-Fonseca F, Bartolomeu F, Alves N, Miranda A, Gasik M, Silva FS, Silva NA, Miranda G. Development of β-TCP-Ti6Al4V structures: Driving cellular response by modulating physical and chemical properties. Materials Science & Engineering. C, Materials For Biological Applications. 98: 705-716. PMID 30813075 DOI: 10.1016/J.Msec.2019.01.016  0.559
2019 Gomes ED, Silva NA, Salgado AJ. Combinatorial therapies for spinal cord injury: strategies to induce regeneration. Neural Regeneration Research. 14: 69-71. PMID 30531075 DOI: 10.4103/1673-5374.243705  0.767
2018 Serra SC, Costa JC, Assunção-Silva RC, Teixeira FG, Silva NA, Anjo SI, Manadas B, Gimble J, Behie LA, Salgado AJ. Influence of Passage Number on the Impact of the Secretome of Adipose Tissue Stem Cells on Neural Survival, Neurodifferentiation and Axonal Growth. Biochimie. PMID 30342112 DOI: 10.1016/J.Biochi.2018.09.012  0.704
2018 Monteiro S, Salgado AJ, Silva NA. Immunomodulation as a neuroprotective strategy after spinal cord injury. Neural Regeneration Research. 13: 423-424. PMID 29623924 DOI: 10.4103/1673-5374.228722  0.737
2018 Gomes ED, Mendes SS, Assunção-Silva RC, Teixeira FG, Pires AO, Anjo SI, Manadas B, Leite-Almeida H, Gimble JM, Sousa N, Lepore AC, Silva NA, Salgado AJ. Co-Transplantation of Adipose tissue-derived Stromal Cells and Olfactory Ensheathing Cells for Spinal Cord Injury Repair. Stem Cells (Dayton, Ohio). PMID 29352743 DOI: 10.1002/Stem.2785  0.849
2018 Melo-Fonseca F, Lima R, Costa M, Bartolomeu F, Alves N, Miranda A, Gasik M, Silva F, Silva N, Miranda G. 45S5 BAG-Ti6Al4V structures: The influence of the design on some of the physical and chemical interactions that drive cellular response Materials & Design. 160: 95-105. DOI: 10.1016/J.Matdes.2018.08.056  0.553
2017 Oliveira E, Assunção-Silva RC, Ziv-Polat O, Gomes ED, Teixeira FG, Silva NA, Shahar A, Salgado AJ. Influence of Different ECM-Like Hydrogels on Neurite Outgrowth Induced by Adipose Tissue-Derived Stem Cells. Stem Cells International. 2017: 6319129. PMID 29333166 DOI: 10.1155/2017/6319129  0.803
2017 Lima R, Monteiro S, Lopes JP, Barradas P, Vasconcelos NL, Gomes ED, Assunção-Silva RC, Teixeira FG, Morais M, Sousa N, Salgado AJ, Silva NA. Systemic Interleukin-4 Administration after Spinal Cord Injury Modulates Inflammation and Promotes Neuroprotection. Pharmaceuticals (Basel, Switzerland). 10. PMID 29064422 DOI: 10.3390/Ph10040083  0.795
2016 Gomes ED, Mendes SS, Leite-Almeida H, Gimble JM, Tam RY, Shoichet MS, Sousa N, Silva NA, Salgado AJ. Combination of a peptide-modified gellan gum hydrogel with cell therapy in a lumbar spinal cord injury animal model. Biomaterials. 105: 38-51. PMID 27505621 DOI: 10.1016/J.Biomaterials.2016.07.019  0.857
2016 Pires A, Pinheiro B, Teixeira FG, Anjo S, Samy S, Gomes E, Serra S, Silva NA, Manadas B, Sousa N, Salgado AJ. Unveiling the Differences of Secretome of Human Bone Marrow Mesenchymal Stem Cells, Adipose Tissue derived Stem Cells and Human Umbilical Cord Perivascular Cells: A Proteomic Analysis. Stem Cells and Development. PMID 27226274 DOI: 10.1089/scd.2016.0048  0.8
2016 Teixeira FG, Vasconcelos NL, Gomes ED, Marques F, Sousa JC, Sousa N, Silva NA, Assunção-Silva R, Lima R, Salgado AJ. Bioengineered cell culture systems of central nervous system injury and disease. Drug Discovery Today. PMID 27132519 DOI: 10.1016/J.Drudis.2016.04.020  0.778
2016 Vasconcelos NL, Gomes ED, Oliveira EP, Silva CJ, Lima R, Sousa N, Salgado AJ, Silva NA. Combing neuroprotective agents: effect of riluzole and magnesium in a rat model of thoracic spinal cord injury. The Spine Journal : Official Journal of the North American Spine Society. PMID 27109831 DOI: 10.1016/J.Spinee.2016.04.013  0.831
2016 Cerqueira SR, Oliveira JM, Silva NA, Leite-Almeida H, Ribeiro-Samy S, Almeida A, Mano JF, Sousa N, Salgado AJ, Reis RL. Microglia Response and In Vivo Therapeutic Potential of Methylprednisolone-Loaded Dendrimer Nanoparticles in Spinal Cord Injury. Small (Weinheim An Der Bergstrasse, Germany). 12: 972. PMID 26890375 DOI: 10.1002/smll.201503492  0.82
2016 Fraga J, Silva N, Lourenço A, Gonçalves V, Neves N, Reis R, Rodrigues A, Manadas B, Sousa N, Salgado A. Corrigendum to ‘Unveiling the effects of the secretome of mesenchymal progenitors from the umbilical cord in different neuronal cell populations’ [Biochimie 95–12 (2013) 2297–2303] Biochimie. 121: 336. DOI: 10.1016/J.Biochi.2015.11.025  0.792
2015 Assunção-Silva RC, Oliveira CC, Ziv-Polat O, Gomes ED, Sahar A, Sousa N, Silva NA, Salgado AJ. Induction of neurite outgrowth in 3D hydrogel-based environments. Biomedical Materials (Bristol, England). 10: 051001. PMID 26480959 DOI: 10.1088/1748-6041/10/5/051001  0.794
2015 Canha-Gouveia A, Rita Costa-Pinto A, Martins AM, Silva NA, Faria S, Sousa RA, Salgado AJ, Sousa N, Reis RL, Neves NM. Hierarchical scaffolds enhance osteogenic differentiation of human Wharton's jelly derived stem cells. Biofabrication. 7: 035009. PMID 26335618 DOI: 10.1088/1758-5090/7/3/035009  0.764
2015 da Mota LM, Cruz BA, Albuquerque CP, Gonçalves D, Laurindo IM, Pereira IA, Carvalho JF, Pinheiro Gda R, Bertolo MB, Silva NA, Louzada Júnior P, Xavier RM, Giorgi RD, Lima RA. [Preliminary guidelines of the Brazilian Society of Rheumatology for evaluation and treatment of tuberculosis latent infection in patients with rheumatoid arthritis, in face of unavailability of the tuberculin skin test]. Revista Brasileira De Reumatologia. 55: 390-3. PMID 26165801 DOI: 10.1016/j.rbr.2015.01.006  0.457
2015 Assunção-Silva RC, Gomes ED, Sousa N, Silva NA, Salgado AJ. Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration. Stem Cells International. 2015: 948040. PMID 26124844 DOI: 10.1155/2015/948040  0.844
2015 Mota LM, Cruz BA, Brenol CV, Pollak DF, Pinheiro Gda R, Laurindo IM, Pereira IA, Carvalho JF, Bertolo MB, Pinheiro Mde M, Freitas MV, Silva NA, Louzada-Júnior P, Sampaio-Barros PD, Giorgi RD, et al. [Safe use of biological therapies for the treatment of rheumatoid arthritis and spondyloarthritides]. Revista Brasileira De Reumatologia. 55: 281-309. PMID 26054442 DOI: 10.1016/j.rbr.2014.06.006  0.507
2014 Sevivas N, Serra SC, Portugal R, Teixeira FG, Carvalho MM, Silva N, Espregueira-Mendes J, Sousa N, Salgado AJ. Animal model for chronic massive rotator cuff tear: behavioural and histologic analysis Knee Surgery, Sports Traumatology, Arthroscopy. 23: 608-618. PMID 25416674 DOI: 10.1007/S00167-014-3441-3  0.766
2014 Rezende GM, Viana VS, Malheiros DM, Borba EF, Silva NA, Silva C, Leon EP, Noronha IL, Bonfa E. Podocyte injury in pure membranous and proliferative lupus nephritis: distinct underlying mechanisms of proteinuria? Lupus. 23: 255-62. PMID 24356611 DOI: 10.1177/0961203313517152  0.364
2014 Silva NA, Sousa N, Reis RL, Salgado AJ. From basics to clinical: a comprehensive review on spinal cord injury. Progress in Neurobiology. 114: 25-57. PMID 24269804 DOI: 10.1016/J.Pneurobio.2013.11.002  0.828
2013 Salgado AJ, Oliveira JM, Martins A, Teixeira FG, Silva NA, Neves NM, Sousa N, Reis RL. Tissue engineering and regenerative medicine: past, present, and future. International Review of Neurobiology. 108: 1-33. PMID 24083429 DOI: 10.1016/B978-0-12-410499-0.00001-0  0.756
2013 Ribeiro-Samy S, Silva NA, Correlo VM, Fraga JS, Pinto L, Teixeira-Castro A, Leite-Almeida H, Almeida A, Gimble JM, Sousa N, Salgado AJ, Reis RL. Development and characterization of a PHB-HV-based 3D scaffold for a tissue engineering and cell-therapy combinatorial approach for spinal cord injury regeneration. Macromolecular Bioscience. 13: 1576-92. PMID 24038969 DOI: 10.1002/Mabi.201300178  0.833
2013 Silva NA, Moreira J, Ribeiro-Samy S, Gomes ED, Tam RY, Shoichet MS, Reis RL, Sousa N, Salgado AJ. Modulation of bone marrow mesenchymal stem cell secretome by ECM-like hydrogels. Biochimie. 95: 2314-9. PMID 23994751 DOI: 10.1016/J.Biochi.2013.08.016  0.795
2013 Mota LM, Cruz BA, Brenol CV, Pereira IA, Rezende-Fronza LS, Bertolo MB, Freitas MV, Silva NA, Louzada-Junior P, Giorgi RD, Giorgio RD, Lima RA, Bernardo WM, Pinheiro Gda R. Guidelines for the drug treatment of rheumatoid arthritis. Revista Brasileira De Reumatologia. 53: 158-83. PMID 23856794  0.466
2013 Mota LM, Cruz BA, Brenola CV, Brenol CV, Pereira IA, Rezende-Fronza LS, Bertolo MB, Freitas MV, Silva NA, Louzada-Junior P, Giorgi RD, Giorgio RD, Lima RA, Kairalla RA, Kawassaki Ade M, et al. Guidelines for the diagnosis of rheumatoid arthritis. Revista Brasileira De Reumatologia. 53: 141-57. PMID 23856793  0.445
2013 Fraga JS, Silva NA, Lourenço AS, Gonçalves V, Neves NM, Reis RL, Rodrigues AJ, Manadas B, Sousa N, Salgado AJ. Unveiling the effects of the secretome of mesenchymal progenitors from the umbilical cord in different neuronal cell populations. Biochimie. 95: 2297-303. PMID 23851197 DOI: 10.1016/J.Biochi.2013.06.028  0.76
2013 Brenol CV, da Mota LM, Cruz BA, Pileggi GS, Pereira IA, Rezende LS, Bertolo MB, Freitas MV, Silva NA, Louzada-Junior P, Giorgi RD, Lima RA, Pinheiro Gda R. 2012 Brazilian Society of Rheumatology Consensus on vaccination of patients with rheumatoid arthritis. Revista Brasileira De Reumatologia. 53: 4-23. PMID 23588512  0.447
2013 Silva NA, Gimble JM, Sousa N, Reis RL, Salgado AJ. Combining adult stem cells and olfactory ensheathing cells: the secretome effect. Stem Cells and Development. 22: 1232-40. PMID 23316915 DOI: 10.1089/Scd.2012.0524  0.803
2013 Cerqueira SR, Oliveira JM, Silva NA, Leite-Almeida H, Ribeiro-Samy S, Almeida A, Mano JF, Sousa N, Salgado AJ, Reis RL. Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injury. Small (Weinheim An Der Bergstrasse, Germany). 9: 738-49. PMID 23161735 DOI: 10.1002/Smll.201201888  0.805
2013 Silva NA, Sousa RA, Fraga JS, Fontes M, Leite-Almeida H, Cerqueira R, Almeida A, Sousa N, Reis RL, Salgado AJ. Benefits of spine stabilization with biodegradable scaffolds in spinal cord injured rats. Tissue Engineering. Part C, Methods. 19: 101-8. PMID 22779715 DOI: 10.1089/Ten.Tec.2012.0264  0.832
2012 Oliveira AL, Sousa EC, Silva NA, Sousa N, Salgado AJ, Reis RL. Peripheral mineralization of a 3D biodegradable tubular construct as a way to enhance guidance stabilization in spinal cord injury regeneration. Journal of Materials Science. Materials in Medicine. 23: 2821-30. PMID 22903600 DOI: 10.1007/S10856-012-4741-0  0.825
2012 Pereira IA, Mota LM, Cruz BA, Brenol CV, Fronza LS, Bertolo MB, Freitas MV, Silva NA, Louzada-Junior P, Giorgi RD, Lima RA, Pinheiro Gda R. 2012 Brazilian Society of Rheumatology Consensus on the management of comorbidities in patients with rheumatoid arthritis. Revista Brasileira De Reumatologia. 52: 474-95. PMID 22885417 DOI: 10.1590/S0482-50042012000400002  0.447
2012 Silva NA, Cooke MJ, Tam RY, Sousa N, Salgado AJ, Reis RL, Shoichet MS. The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fate Biomaterials. 33: 6345-6354. PMID 22698724 DOI: 10.1016/J.Biomaterials.2012.05.050  0.808
2012 Silva NA, Sousa RA, Pires AO, Sousa N, Salgado AJ, Reis RL. Interactions between Schwann and olfactory ensheathing cells with a starch/polycaprolactone scaffold aimed at spinal cord injury repair. Journal of Biomedical Materials Research. Part A. 100: 470-6. PMID 22125000 DOI: 10.1002/Jbm.A.33289  0.836
2011 Ribeiro CA, Salgado AJ, Fraga JS, Silva NA, Reis RL, Sousa N. The secretome of bone marrow mesenchymal stem cells-conditioned media varies with time and drives a distinct effect on mature neurons and glial cells (primary cultures). Journal of Tissue Engineering and Regenerative Medicine. 5: 668-72. PMID 21774090 DOI: 10.1002/Term.365  0.764
2010 Silva NA, Salgado AJ, Sousa RA, Oliveira JT, Pedro AJ, Leite-Almeida H, Cerqueira R, Almeida A, Mastronardi F, Mano JF, Neves NM, Sousa N, Reis RL. Development and characterization of a novel hybrid tissue engineering-based scaffold for spinal cord injury repair. Tissue Engineering. Part A. 16: 45-54. PMID 19614546 DOI: 10.1089/Ten.Tea.2008.0559  0.819
2008 Salgado AJ, Sousa N, Silva NA, Neves NM, Reis RL. Hydrogels for spinal cord injury regeneration Natural-Based Polymers For Biomedical Applications. 570-594. DOI: 10.1533/9781845694814.4.570  0.791
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