☰

Ralf Landgraf - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Biochemistry, Cell Biology, Oncology
Tree Info Similar researchers PubMed Report error

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Agarwal NK, Kim CH, Kunkalla K, Vaghefi A, Sanchez S, Manuel S, Bilbao D, Vega F, Landgraf R. Smoothened (SMO) regulates insulin-like growth factor 1 receptor (IGF1R) levels and protein kinase B (AKT) localization and signaling. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 34893758 DOI: 10.1038/s41374-021-00702-6  0.346
2019 Agarwal N, Kunkalla K, Bilbao D, Landgraf R, Vega F. Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma Blood. 134: 3972-3972. DOI: 10.1182/Blood-2019-121847  0.422
2018 Qu C, Kunkalla K, Vaghefi A, Frederiksen JK, Liu Y, Chapman JR, Blonska M, Bernal-Mizrachi L, Alderuccio JP, Lossos IS, Landgraf R, Vega F. Smoothened Stabilizes and Protects TRAF6 from Degradation: A Novel Non-Canonical Role of Smoothened with Implications in Lymphoma Biology. Cancer Letters. PMID 30165192 DOI: 10.1016/J.Canlet.2018.08.020  0.37
2018 Garri C, Howell S, Tiemann K, Tiffany A, Jalali-Yazdi F, Alba MM, Katz JE, Takahashi TT, Landgraf R, Gross ME, Roberts RW, Kani K. Identification, characterization and application of a new peptide against anterior gradient homolog 2 (AGR2). Oncotarget. 9: 27363-27379. PMID 29937991 DOI: 10.18632/Oncotarget.25221  0.528
2017 Lee H, Landgraf R, Wilson JN. Synthesis and photophysical properties of a fluorescent cyanoquinoline probe for profiling ERBB2 kinase inhibitor response. Bioorganic & Medicinal Chemistry. PMID 28974323 DOI: 10.1016/J.Bmc.2017.09.034  0.414
2016 Lee H, Liu W, Brown AS, Landgraf R, Wilson JN. Fluorescent Kinase Probes Enabling Identification and Dynamic Imaging of HER2(+) Cells. Analytical Chemistry. 88: 11310-11313. PMID 27934102 DOI: 10.1021/Acs.Analchem.6B03836  0.511
2016 Liu W, Barnette AR, Adreansky S, Landgraf R. ERBB2 overexpression establishes ERBB3 dependent hypersensitivity of breast cancer cells to Withaferin A. Molecular Cancer Therapeutics. PMID 27474152 DOI: 10.1158/1535-7163.Mct-15-0932  0.462
2016 Astudillo L, da Silva TG, Wang Z, Han X, Jin K, VanWye J, Zhu X, Weaver KL, Oashi T, Lopes PE, Orton D, Neitzel LR, Lee E, Landgraf R, Robbins DJ, et al. The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis. Cancer Research. PMID 27197169 DOI: 10.1158/0008-5472.Can-16-0061  0.362
2016 Keramisanou D, Aboalroub A, Zhang Z, Liu W, Marshall D, Diviney A, Larsen RW, Landgraf R, Gelis I. Molecular Mechanism of Protein Kinase Recognition and Sorting by the Hsp90 Kinome-Specific Cochaperone Cdc37. Molecular Cell. 62: 260-271. PMID 27105117 DOI: 10.1016/J.Molcel.2016.04.005  0.43
2016 Braley A, Kwak T, Jules J, Harja E, Landgraf R, Hudson BI. Regulation of RAGE ectodomain shedding and its role in cell function. The Journal of Biological Chemistry. PMID 27022018 DOI: 10.1074/Jbc.M115.702399  0.433
2015 Wilson JN, Liu W, Brown AS, Landgraf R. Binding-induced, turn-on fluorescence of the EGFR/ERBB kinase inhibitor, lapatinib. Organic & Biomolecular Chemistry. 13: 5006-11. PMID 25820099 DOI: 10.1039/C5Ob00239G  0.423
2015 Liu W, Landgraf R. Phosphorylated and unphosphorylated serine 13 of CDC37 stabilize distinct interactions between its client and HSP90 binding domains. Biochemistry. 54: 1493-504. PMID 25619116 DOI: 10.1021/Bi501129G  0.44
2015 Lu X, Sicard R, Jiang X, Stockus JN, McNamara G, Abdulreda M, Moy VT, Landgraf R, Lossos IS. HGAL localization to cell membrane regulates B-cell receptor signaling. Blood. 125: 649-57. PMID 25381061 DOI: 10.1182/Blood-2014-04-571331  0.414
2014 Dhuguru J, Liu W, Gonzalez WG, Babinchak WM, Miksovska J, Landgraf R, Wilson JN. Emission tuning of fluorescent kinase inhibitors: conjugation length and substituent effects. The Journal of Organic Chemistry. 79: 4940-7. PMID 24784897 DOI: 10.1021/Jo500520X  0.39
2013 Patel N, Barrientos A, Landgraf R. The growth factor receptor ERBB2 regulates mitochondrial activity on a signaling time scale. The Journal of Biological Chemistry. 288: 35253-65. PMID 24142693 DOI: 10.1074/Jbc.M113.478271  0.397
2013 Macdonald-Obermann JL, Adak S, Landgraf R, Piwnica-Worms D, Pike LJ. Dynamic analysis of the epidermal growth factor (EGF) receptor-ErbB2-ErbB3 protein network by luciferase fragment complementation imaging. The Journal of Biological Chemistry. 288: 30773-84. PMID 24014028 DOI: 10.1074/Jbc.M113.489534  0.514
2013 Ward TM, Iorns E, Liu X, Hoe N, Kim P, Singh S, Dean S, Jegg AM, Gallas M, Rodriguez C, Lippman M, Landgraf R, Pegram MD. Truncated p110 ERBB2 induces mammary epithelial cell migration, invasion and orthotopic xenograft formation, and is associated with loss of phosphorylated STAT5. Oncogene. 32: 2463-74. PMID 22751112 DOI: 10.1038/Onc.2012.256  0.382
2012 Jegg AM, Ward TM, Iorns E, Hoe N, Zhou J, Liu X, Singh S, Landgraf R, Pegram MD. PI3K independent activation of mTORC1 as a target in lapatinib-resistant ERBB2+ breast cancer cells. Breast Cancer Research and Treatment. 136: 683-92. PMID 23089982 DOI: 10.1007/S10549-012-2252-9  0.388
2012 Sicard R, Dhuguru J, Liu W, Patel N, Landgraf R, Wilson JN. A fluorescent reporter of ATP binding-competent receptor kinases. Bioorganic & Medicinal Chemistry Letters. 22: 5532-5. PMID 22868229 DOI: 10.1016/J.Bmcl.2012.07.034  0.507
2012 Zhang Q, Park E, Kani K, Landgraf R. Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 13237-42. PMID 22733765 DOI: 10.1073/Pnas.1200105109  0.752
2011 Zhang Q, Park E, Kani K, Landgraf R. Abstract C58: Heterotetramers of ERBB2 and ERBB3 generate qualitatively distinct signals from heterodimers and provide most of the neuregulin-induced phosphorylation of ERBB2 Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C58  0.672
2011 Ward TM, Iorns E, Liu X, Singh S, Kim P, Jegg A, Dean S, Gallas M, Villasboas-Bisneto J, Lippman M, Landgraf R, Pegram M. Abstract 1211: Novel detection and characterization of truncated ERBB2 demonstrates potent oncogenicity of the p110 isoform in human mammary epithelial cells Cancer Research. 71: 1211-1211. DOI: 10.1158/1538-7445.Am2011-1211  0.351
2011 Patel NM, Xiang J, Warren C, Avliyakulov N, Haykinson M, Landgraf R. Abstract 1210: Activation of heterogeneous nuclear ribonucleoprotein K (HNRNPK) by ERBB2/ERBB3 Cancer Research. 71: 1210-1210. DOI: 10.1158/1538-7445.Am2011-1210  0.645
2010 Gerbin CS, Landgraf R. Geldanamycin selectively targets the nascent form of ERBB3 for degradation. Cell Stress & Chaperones. 15: 529-44. PMID 20084478 DOI: 10.1007/S12192-009-0166-1  0.679
2010 Ward T, Iorns E, Singh S, Jegg A, Gallas M, Lippman M, Landgraf R, Pegram M. Abstract P5-06-03: Truncated ERBB2 Receptors: Diagnostic and Therapeutic Targets Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P5-06-03  0.324
2009 Ward T, Iorns E, Gallas M, Lippman M, Landgraf R, Pegram M. Truncated p95erbB2Isoforms Are Capable of Transforming Human Mammary Epithelial Cells. Cancer Research. 69: 3136-3136. DOI: 10.1158/0008-5472.Sabcs-09-3136  0.312
2008 Park E, Baron R, Landgraf R. Higher-order association states of cellular ERBB3 probed with photo-cross-linkable aptamers. Biochemistry. 47: 11992-2005. PMID 18942860 DOI: 10.1021/Bi8004208  0.674
2007 Landgraf R. HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks. Breast Cancer Research : Bcr. 9: 202. PMID 17274834 DOI: 10.1186/Bcr1633  0.453
2006 Warren CM, Kani K, Landgraf R. The N-terminal domains of neuregulin 1 confer signal attenuation. The Journal of Biological Chemistry. 281: 27306-16. PMID 16825199 DOI: 10.1074/Jbc.M512887200  0.721
2006 Warren CM, Landgraf R. Signaling through ERBB receptors: multiple layers of diversity and control. Cellular Signalling. 18: 923-33. PMID 16460914 DOI: 10.1016/J.Cellsig.2005.12.007  0.689
2005 Kani K, Park E, Landgraf R. The extracellular domains of ErbB3 retain high ligand binding affinity at endosome pH and in the locked conformation. Biochemistry. 44: 15842-57. PMID 16313187 DOI: 10.1021/Bi0515220  0.704
2005 Kani K, Warren CM, Kaddis CS, Loo JA, Landgraf R. Oligomers of ERBB3 have two distinct interfaces that differ in their sensitivity to disruption by heregulin. The Journal of Biological Chemistry. 280: 8238-47. PMID 15611073 DOI: 10.1074/Jbc.M410944200  0.73
2003 Chen CH, Chernis GA, Hoang VQ, Landgraf R. Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3. Proceedings of the National Academy of Sciences of the United States of America. 100: 9226-31. PMID 12874383 DOI: 10.1073/Pnas.1332660100  0.51
2001 Singer E, Landgraf R, Horan T, Slamon D, Eisenberg D. Identification of a heregulin binding site in HER3 extracellular domain. The Journal of Biological Chemistry. 276: 44266-74. PMID 11555649 DOI: 10.1074/Jbc.M105428200  0.436
2000 Landgraf R, Eisenberg D. Heregulin reverses the oligomerization of HER3. Biochemistry. 39: 8503-11. PMID 10913256 DOI: 10.1021/Bi000953+  0.407
2000 Atienza JM, Suh M, Xenarios I, Landgraf R, Colicelli J. Human ERK1 induces filamentous growth and cell wall remodeling pathways in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 275: 20638-46. PMID 10787425 DOI: 10.1074/Jbc.M910024199  0.382
2000 Landgraf R, Fischer D, Eisenberg D. Analysis of heregulin symmetry by weighted evolutionary tracing. Protein Engineering. 12: 943-51. PMID 10585499 DOI: 10.1093/Protein/12.11.943  0.378
1998 Landgraf R, Pegram M, Slamon DJ, Eisenberg D. Cytotoxicity and specificity of directed toxins composed of diphtheria toxin and the EGF-like domain of heregulin beta1. Biochemistry. 37: 3220-8. PMID 9485477 DOI: 10.1021/Bi972326Z  0.499
1994 Landgraf R, Chen CH, Sigman DS. Oligonucleotide-directed nucleic acid scission by micrococcal nuclease. Biochemistry. 33: 10607-15. PMID 8075060 DOI: 10.1021/Bi00201A006  0.308
Show low-probability matches.