Zdenko Herceg, D.V.M - Ph.D. - Publications

Affiliations: 
Epigenetics International Agency for Research on Cancer - WHO 
Area:
epigenetics, cancer, dna methylation, histones modifications

174 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li S, Spitz N, Ghantous A, Abrishamcar S, Reimann B, Marques I, Silver MJ, Aguilar-Lacasaña S, Kitaba N, Rezwan FI, Röder S, Sirignano L, Tuhkanen J, Mancano G, Sharp GC, ... ... Herceg Z, et al. A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation. Communications Biology. 7: 66. PMID 38195839 DOI: 10.1038/s42003-023-05698-x  0.305
2022 Manara F, Jay A, Odongo GA, Mure F, Maroui MA, Diederichs A, Sirand C, Cuenin C, Granai M, Mundo L, Hernandez-Vargas H, Lazzi S, Khoueiry R, Gruffat H, Herceg Z, et al. Epigenetic Alteration of the Cancer-Related Gene TGFBI in B Cells Infected with Epstein-Barr Virus and Exposed to Aflatoxin B1: Potential Role in Burkitt Lymphoma Development. Cancers. 14. PMID 35267594 DOI: 10.3390/cancers14051284  0.315
2022 Silver MJ, Saffari A, Kessler NJ, Chandak GR, Fall CHD, Issarapu P, Dedaniya A, Betts M, Moore SE, Routledge MN, Herceg Z, Cuenin C, Derakhshan M, James PT, Monk D, et al. Environmentally sensitive hotspots in the methylome of the early human embryo. Elife. 11. PMID 35188105 DOI: 10.7554/eLife.72031  0.312
2022 Bošković M, Roje B, Chung FF, Gelemanović A, Cahais V, Cuenin C, Khoueiry R, Vilović K, Herceg Z, Terzić J. DNA Methylome Changes of Muscle- and Neuronal-Related Processes Precede Bladder Cancer Invasiveness. Cancers. 14. PMID 35158756 DOI: 10.3390/cancers14030487  0.326
2021 Ghantous A, Novoloaca A, Bouaoun L, Cuenin C, Cros MP, Xu Y, Hernandez-Vargas H, Darboe MK, Prentice AM, Moore SE, Gong YY, Herceg Z, Routledge MN. Aflatoxin Exposure during Early Life Is Associated with Differential DNA Methylation in Two-Year-Old Gambian Children. International Journal of Molecular Sciences. 22. PMID 34445674 DOI: 10.3390/ijms22168967  0.33
2021 Soares-Lima SC, Mehanna H, Camuzi D, de Souza-Santos PT, Simão TA, Nicolau-Neto P, Almeida Lopes MS, Cuenin C, Talukdar FR, Batis N, Costa I, Dias F, Degli Esposti D, Boroni M, Herceg Z, et al. Upper Aerodigestive Tract Squamous Cell Carcinomas Show Distinct Overall DNA Methylation Profiles and Different Molecular Mechanisms behind WNT Signaling Disruption. Cancers. 13. PMID 34208581 DOI: 10.3390/cancers13123014  0.317
2021 Woo HD, Herceg Z. A Method to Investigate the Helicobacter pylori-Associated DNA Methylome. Methods in Molecular Biology (Clifton, N.J.). 2283: 75-81. PMID 33765311 DOI: 10.1007/978-1-0716-1302-3_9  0.308
2020 Foy JP, Bertolus C, Boutolleau D, Agut H, Gessain A, Herceg Z, Saintigny P. Arguments to Support a Viral Origin of Oral Squamous Cell Carcinoma in Non-Smoker and Non-Drinker Patients. Frontiers in Oncology. 10: 822. PMID 32528893 DOI: 10.3389/Fonc.2020.00822  0.303
2020 Eze IC, Jeong A, Schaffner E, Rezwan FI, Ghantous A, Foraster M, Vienneau D, Kronenberg F, Herceg Z, Vineis P, Brink M, Wunderli JM, Schindler C, Cajochen C, Röösli M, et al. Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study. Environmental Health Perspectives. 128: 67003. PMID 32484729 DOI: 10.1289/Ehp6174  0.319
2020 Merid SK, Novoloaca A, Sharp GC, Küpers LK, Kho AT, Roy R, Gao L, Annesi-Maesano I, Jain P, Plusquin M, Kogevinas M, Allard C, Vehmeijer FO, Kazmi N, Salas LA, ... ... Herceg Z, et al. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Medicine. 12: 25. PMID 32114984 DOI: 10.1186/S13073-020-0716-9  0.365
2019 Patil V, Cuenin C, Chung F, Aguilera JRR, Fernandez-Jimenez N, Romero-Garmendia I, Bilbao JR, Cahais V, Rothwell J, Herceg Z. Human mitochondrial DNA is extensively methylated in a non-CpG context. Nucleic Acids Research. 47: 10072-10085. PMID 31665742 DOI: 10.1093/Nar/Gkz762  0.441
2019 Koroknai V, Szász I, Hernandez-Vargas H, Fernandez-Jimenez N, Cuenin C, Herceg Z, Vízkeleti L, Ádány R, Ecsedi S, Balázs M. DNA hypermethylation is associated with invasive phenotype of malignant melanoma. Experimental Dermatology. PMID 31602702 DOI: 10.1111/Exd.14047  0.445
2019 Howe CG, Cox B, Fore R, Jungius J, Kvist T, Lent S, Miles HE, Salas LA, Rifas-Shiman S, Starling AP, Yousefi P, Ladd-Acosta C, Baccarelli A, Binder EB, Chatzi VL, ... ... Herceg Z, et al. Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium. Diabetes Care. PMID 31601636 DOI: 10.2337/Dc19-0524  0.347
2019 Awada Z, Nasr R, Akika R, Cahais V, Cuenin C, Zhivagui M, Herceg Z, Ghantous A, Zgheib NK. DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer. Clinical Epigenetics. 11: 138. PMID 31601247 DOI: 10.1186/S13148-019-0725-Y  0.388
2019 Pez F, Gifu P, Degli-Esposti D, Fares N, Lopez A, Lefrançois L, Michelet M, Rivoire M, Bancel B, Sylla BS, Herceg Z, Merle P, Caron de Fromentel C. In vitro transformation of primary human hepatocytes: Epigenetic changes and stemness properties. Experimental Cell Research. 111643. PMID 31557464 DOI: 10.1016/J.Yexcr.2019.111643  0.324
2019 Sikdar S, Joehanes R, Joubert BR, Xu CJ, Vives-Usano M, Rezwan FI, Felix JF, Ward JM, Guan W, Richmond RC, Brody JA, Küpers LK, Baïz N, Håberg SE, Smith JA, ... ... Herceg Z, et al. Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking. Epigenomics. PMID 31536415 DOI: 10.2217/Epi-2019-0066  0.341
2019 Josipović G, Tadić V, Klasić M, Zanki V, Bečeheli I, Chung F, Ghantous A, Keser T, Madunić J, Bošković M, Lauc G, Herceg Z, Vojta A, Zoldoš V. Antagonistic and synergistic epigenetic modulation using orthologous CRISPR/dCas9-based modular system. Nucleic Acids Research. PMID 31410472 DOI: 10.1093/Nar/Gkz709  0.361
2019 Herceg Z, Ambatipudi S. Smoking-associated DNA methylation changes: no smoke without fire. Epigenomics. PMID 31339344 DOI: 10.2217/Epi-2019-0136  0.321
2019 Gruzieva O, Xu CJ, Yousefi P, Relton C, Merid SK, Breton CV, Gao L, Volk HE, Feinberg JI, Ladd-Acosta C, Bakulski K, Auffray C, Lemonnier N, Plusquin M, Ghantous A, ... Herceg Z, et al. Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis. Environmental Health Perspectives. 127: 57012. PMID 31148503 DOI: 10.1289/Ehp4522  0.34
2019 Bodelon C, Ambatipudi S, Dugué PA, Johansson A, Sampson JN, Hicks B, Karlins E, Hutchinson A, Cuenin C, Chajès V, Southey MC, Romieu I, Giles GG, English D, Polidoro S, ... ... Herceg Z, et al. Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies. Breast Cancer Research : Bcr. 21: 62. PMID 31101124 DOI: 10.1186/S13058-019-1145-9  0.441
2019 Johansson A, Palli D, Masala G, Grioni S, Agnoli C, Tumino R, Giurdanella MC, Fasanelli F, Sacerdote C, Panico S, Mattiello A, Polidoro S, Jones ME, Schoemaker MJ, Orr N, ... ... Herceg Z, et al. Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk. Clinical Epigenetics. 11: 66. PMID 31039828 DOI: 10.1186/S13148-019-0664-7  0.375
2019 Reimann B, Janssen BG, Alfano R, Ghantous A, Espín-Pérez A, de Kok TM, Saenen ND, Cox B, Robinson O, Chadeau-Hyam M, Penders J, Herceg Z, Vineis P, Nawrot TS, Plusquin M. The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome. Frontiers in Genetics. 10: 325. PMID 31031804 DOI: 10.3389/Fgene.2019.00325  0.303
2019 Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, ... ... Herceg Z, et al. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nature Communications. 10: 1893. PMID 31015461 DOI: 10.1038/S41467-019-09671-3  0.409
2019 Vargas-Ayala RC, Jay A, Manara F, Maroui MA, Hernandez-Vargas H, Diederichs A, Robitaille A, Sirand C, Ceraolo MG, Romero-Medina MC, Cros MP, Cuenin C, Durand G, Le Calvez-Kelm F, Mundo L, ... ... Herceg Z, et al. Interplay between the epigenetic enzyme lysine (K)-specific demethylase 2B and Epstein-Barr virus infection. Journal of Virology. PMID 30996097 DOI: 10.1128/Jvi.00273-19  0.4
2019 Perrier F, Viallon V, Ambatipudi S, Ghantous A, Cuenin C, Hernandez-Vargas H, Chajès V, Baglietto L, Matejcic M, Moreno-Macias H, Kühn T, Boeing H, Karakatsani A, Kotanidou A, Trichopoulou A, ... ... Herceg Z, et al. Association of leukocyte DNA methylation changes with dietary folate and alcohol intake in the EPIC study. Clinical Epigenetics. 11: 57. PMID 30940212 DOI: 10.1186/S13148-019-0637-X  0.408
2019 Silva IR, Ramos MCAS, Arantes LMRB, Lengert AVH, Oliveira MA, Cury FP, Martins Pereira G, Santos AG, Barbosa F, Vasconcellos PC, Cuenin C, Herceg Z, Silveira HCS. Evaluation of DNA Methylation Changes and Micronuclei in Workers Exposed to a Construction Environment. International Journal of Environmental Research and Public Health. 16. PMID 30871143 DOI: 10.3390/Ijerph16060902  0.407
2019 Jeong A, Imboden M, Ghantous A, Novoloaca A, Carsin AE, Kogevinas M, Schindler C, Lovison G, Herceg Z, Cuenin C, Vermeulen R, Jarvis D, Amaral AFS, Kronenberg F, Vineis P, et al. DNA Methylation in Inflammatory Pathways Modifies the Association between BMI and Adult-Onset Non-Atopic Asthma. International Journal of Environmental Research and Public Health. 16. PMID 30791383 DOI: 10.3390/Ijerph16040600  0.312
2019 Fernandez-Jimenez N, Garcia-Etxebarria K, Plaza-Izurieta L, Romero-Garmendia I, Jauregi-Miguel A, Legarda M, Ecsedi S, Castellanos-Rubio A, Cahais V, Cuenin C, Degli Esposti D, Irastorza I, Hernandez-Vargas H, Herceg Z, Bilbao JR. The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region. Scientific Reports. 9: 1298. PMID 30718669 DOI: 10.1038/S41598-018-37746-6  0.402
2019 Halaburkova A, Cahais V, Cuenin C, Khoueiry R, Ouzounova M, Ghantous A, Herceg Z. Abstract 4313: Identifying and characterizing epigenetic «driver» genes («epidrivers») in regulatory pathways involved in tumorigenesis and tumour cell plasticity Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-4313  0.356
2018 Alfano R, Guida F, Galobardes B, Chadeau-Hyam M, Delpierre C, Ghantous A, Henderson J, Herceg Z, Jain P, Nawrot TS, Relton C, Vineis P, Castagné R, Plusquin M. Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth cohort. International Journal of Epidemiology. PMID 30590607 DOI: 10.1093/Ije/Dyy259  0.32
2018 Tikellis G, Dwyer T, Paltiel O, Phillips GS, Lemeshow S, Golding J, Northstone K, Boyd A, Olsen S, Ghantous A, Herceg Z, Ward MH, Håberg SE, Magnus P, Olsen J, et al. The International Childhood Cancer Cohort Consortium (I4C): A research platform of prospective cohorts for studying the aetiology of childhood cancers. Paediatric and Perinatal Epidemiology. PMID 30466188 DOI: 10.1111/Ppe.12519  0.321
2018 Alfano R, Herceg Z, Nawrot TS, Chadeau-Hyam M, Ghantous A, Plusquin M. The Impact of Air Pollution on Our Epigenome: How Far Is the Evidence? (A Systematic Review). Current Environmental Health Reports. PMID 30361985 DOI: 10.1007/S40572-018-0218-8  0.37
2018 Mostafavi N, Vermeulen R, Ghantous A, Hoek G, Probst-Hensch N, Herceg Z, Tarallo S, Naccarati A, Kleinjans JCS, Imboden M, Jeong A, Morley D, Amaral AFS, van Nunen E, Gulliver J, et al. Acute changes in DNA methylation in relation to 24 h personal air pollution exposure measurements: A panel study in four European countries. Environment International. 120: 11-21. PMID 30055357 DOI: 10.1016/J.Envint.2018.07.026  0.396
2018 Talukdar FR, di Pietro M, Secrier M, Moehler M, Goepfert K, Lima SSC, Pinto LFR, Hendricks D, Parker MI, Herceg Z. Molecular landscape of esophageal cancer: implications for early detection and personalized therapy. Annals of the New York Academy of Sciences. PMID 29917250 DOI: 10.1111/Nyas.13876  0.358
2018 Uribe D, Cardona A, Esposti DD, Cros MP, Cuenin C, Herceg Z, Camargo M, Cortés-Mancera FM. Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines. Annals of Hepatology. 17: 444-460. PMID 29735783 DOI: 10.5604/01.3001.0011.7389  0.406
2018 Plusquin M, Chadeau-Hyam M, Ghantous A, Alfano R, Bustamante M, Chatzi L, Cuenin C, Gulliver J, Herceg Z, Kogevinas M, Nawrot T, Pizzi C, Porta D, Relton C, Richiardi L, et al. DNA methylome marks of exposure to particulate matter at three time points in early life. Environmental Science & Technology. PMID 29597345 DOI: 10.1021/Acs.Est.7B06447  0.351
2018 Perrier F, Novoloaca A, Ambatipudi S, Baglietto L, Ghantous A, Perduca V, Barrdahl M, Harlid S, Ong KK, Cardona A, Polidoro S, Nøst TH, Overvad K, Omichessan H, Dollé M, ... ... Herceg Z, et al. Identifying and correcting epigenetics measurements for systematic sources of variation. Clinical Epigenetics. 10: 38. PMID 29588806 DOI: 10.1186/S13148-018-0471-6  0.363
2018 Woo HD, Fernandez-Jimenez N, Ghantous A, Degli Esposti D, Cuenin C, Cahais V, Choi IJ, Kim YI, Kim J, Herceg Z. Genome-wide profiling of normal gastric mucosa identifies Helicobacter pylori- and cancer-associated DNA methylome changes. International Journal of Cancer. PMID 29574700 DOI: 10.1002/Ijc.31381  0.341
2018 Barouki R, Melén E, Herceg Z, Beckers J, Chen J, Karagas M, Puga A, Xia Y, Chadwick L, Yan W, Audouze K, Slama R, Heindel J, Grandjean P, Kawamoto T, et al. Epigenetics as a mechanism linking developmental exposures to long-term toxicity. Environment International. 114: 77-86. PMID 29499450 DOI: 10.1016/J.Envint.2018.02.014  0.361
2018 Ghantous A, Hernandez-Vargas H, Herceg Z. DNA Methylation Analysis from Blood Spots: Increasing Yield and Quality for Genome-Wide and Locus-Specific Methylation Analysis. Methods in Molecular Biology (Clifton, N.J.). 1708: 605-619. PMID 29224166 DOI: 10.1007/978-1-4939-7481-8_31  0.405
2018 Beltrami CM, Barros-Filho MC, Reis MBd, Marchi FA, Kuasne H, Ambatipudi S, Herceg Z, Kowalski LP, Rogatto SR. Abstract A13: Gene body methylation could regulate the expression of genes associated to papillary thyroid carcinomas Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Tcm17-A13  0.445
2018 Leblay N, Alcala N, Marin DH, Delhomme TM, Giffon T, Ghantous A, Chabrier A, Cuenin C, Altmueller J, Durand G, Voegele C, Lorimier P, Toffart A, Derks J, Brustugun OT, ... ... Herceg Z, et al. Abstract 5358: Multi-omics comparative analyses of pulmonary typical carcinoids, atypical carcinoids, and large-cell neuroendocrine carcinoma Cancer Research. 78: 5358-5358. DOI: 10.1158/1538-7445.Am2018-5358  0.366
2018 Bodelon C, Ambatipudi S, Dugué P, Johansson A, Sampson JN, Southey MC, Giles GG, Polidoro S, Herceg Z, Flanagan JM, Milne RL, Garcia-Closas M. Abstract 3230: Genome-wide blood DNA methylation and breast cancer risk: A meta-analysis of four prospective studies Epidemiology. DOI: 10.1158/1538-7445.Am2018-3230  0.415
2017 Gonzaga IM, Soares Lima SC, Nicolau MC, Nicolau-Neto P, da Costa NM, de Almeida Simão T, Hernandez-Vargas H, Herceg Z, Ribeiro Pinto LF. TFF1 hypermethylation and decreased expression in esophageal squamous cell carcinoma and histologically normal tumor surrounding esophageal cells. Clinical Epigenetics. 9: 130. PMID 29296124 DOI: 10.1186/S13148-017-0429-0  0.4
2017 Aushev VN, Lee E, Zhu J, Gopalakrishnan K, Li Q, Teitelbaum SL, Wetmur JG, Degli Esposti D, Hernandez-Vargas H, Herceg Z, Parada H, Santella RM, Gammon MD, Chen J. Novel predictors of breast cancer survival derived from miRNA activity analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29138345 DOI: 10.1158/1078-0432.Ccr-17-0996  0.312
2017 Fiorito G, Vlaanderen J, Polidoro S, Gulliver J, Galassi C, Ranzi A, Krogh V, Grioni S, Agnoli C, Sacerdote C, Panico S, Tsai MY, Probst-Hensch N, Hoek G, Herceg Z, et al. Oxidative stress and inflammation mediate the effect of air pollution on cardio- and cerebrovascular disease: A prospective study in nonsmokers. Environmental and Molecular Mutagenesis. PMID 29114965 DOI: 10.1002/Em.22153  0.36
2017 Fernandez-Jimenez N, Sklias A, Ecsedi S, Cahais V, Degli-Esposti D, Jay A, Ancey PB, Woo HD, Hernandez-Vargas H, Herceg Z. Lowly methylated region analysis identifies EBF1 as a potential epigenetic modifier in breast cancer. Epigenetics. 0. PMID 29099283 DOI: 10.1080/15592294.2017.1373919  0.433
2017 Mathot P, Grandin M, Devailly G, Souaze F, Cahais V, Moran S, Campone M, Herceg Z, Esteller M, Juin P, Mehlen P, Dante R. DNA methylation signal has a major role in the response of human breast cancer cells to the microenvironment. Oncogenesis. 6: e390. PMID 29058695 DOI: 10.1038/oncsis.2017.88  0.387
2017 Sharp GC, Salas LA, Monnereau C, Allard C, Yousefi P, Everson TM, Bohlin J, Xu Z, Huang RC, Reese SE, Xu CJ, Baïz N, Hoyo C, Agha G, Roy R, ... ... Herceg Z, et al. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium. Human Molecular Genetics. 26: 4067-4085. PMID 29016858 DOI: 10.1093/Hmg/Ddx290  0.369
2017 Dos Reis MB, Barros-Filho MC, Marchi FA, Beltrami CM, Kuasne H, Pinto CAL, Ambatipudi S, Herceg Z, Kowalski LP, Rogatto SR. Prognostic classifier based on genome-wide DNA methylation profiling in well-differentiated thyroid tumors. The Journal of Clinical Endocrinology and Metabolism. PMID 28938489 DOI: 10.1210/Jc.2017-00881  0.451
2017 Herceg Z, Ghantous A, Wild CP, Sklias A, Casati L, Duthie SJ, Fry R, Issa JP, Kellermayer R, Koturbash I, Kondo Y, Lepeule J, Lima SCS, Marsit CJ, Rakyan V, et al. Roadmap for Investigating Epigenome Deregulation and Environmental Origins of Cancer. International Journal of Cancer. PMID 28836271 DOI: 10.1002/Ijc.31014  0.402
2017 Hernandez-Vargas H, Gruffat H, Cros MP, Diederichs A, Sirand C, Vargas-Ayala RC, Jay A, Durand G, Le Calvez-Kelm F, Herceg Z, Manet E, Wild CP, Tommasino M, Accardi R. Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines. Scientific Reports. 7: 5852. PMID 28724958 DOI: 10.1038/S41598-017-05713-2  0.404
2017 Kettunen E, Hernandez-Vargas H, Cros MP, Durand G, Le Calvez-Kelm F, Stuopelyte K, Jarmalaite S, Salmenkivi K, Anttila S, Wolff H, Herceg Z, Husgafvel-Pursiainen K. Asbestos-associated genome-wide DNA methylation changes in lung cancer. International Journal of Cancer. PMID 28722770 DOI: 10.1002/Ijc.30897  0.419
2017 Huskova H, Ardin M, Weninger A, Vargova K, Barrin S, Villar S, Olivier M, Stopka T, Herceg Z, Hollstein M, Zavadil J, Korenjak M. Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing. Oncogene. PMID 28692054 DOI: 10.1038/Onc.2017.215  0.393
2017 Ancey PB, Ecsedi S, Lambert MP, Talukdar FR, Cros MP, Glaise D, Narvaez DM, Chauvet V, Herceg Z, Corlu A, Hernandez-Vargas H. TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors. Stem Cell Reports. PMID 28648900 DOI: 10.1016/J.Stemcr.2017.05.023  0.315
2017 Halaburková A, Jendželovský R, Kovaľ J, Herceg Z, Fedoročko P, Ghantous A. Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A. Clinical Epigenetics. 9: 62. PMID 28603560 DOI: 10.1186/S13148-017-0359-X  0.371
2017 Beltrami CM, Dos Reis MB, Barros-Filho MC, Marchi FA, Kuasne H, Pinto CAL, Ambatipudi S, Herceg Z, Kowalski LP, Rogatto SR. Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas. Clinical Epigenetics. 9: 45. PMID 28469731 DOI: 10.1186/S13148-017-0346-2  0.445
2017 Degli Esposti D, Sklias A, Lima SC, Beghelli-de la Forest Divonne S, Cahais V, Fernandez-Jimenez N, Cros MP, Ecsedi S, Cuenin C, Bouaoun L, Byrnes G, Accardi R, Sudaka A, Giordanengo V, Hernandez-Vargas H, ... ... Herceg Z, et al. Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas. Genome Medicine. 9: 33. PMID 28381277 DOI: 10.1186/S13073-017-0419-Z  0.341
2017 Holmila R, Sklias A, Muller DC, Degli Esposti D, Guilloreau P, Mckay J, Sangrajrang S, Srivatanakul P, Hainaut P, Merle P, Herceg Z, Nogueira da Costa A. Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma. Plos One. 12: e0174265. PMID 28333958 DOI: 10.1371/Journal.Pone.0174265  0.378
2017 Ambatipudi S, Horvath S, Perrier F, Cuenin C, Hernandez-Vargas H, Le Calvez-Kelm F, Durand G, Byrnes G, Ferrari P, Bouaoun L, Sklias A, Chajes V, Overvad K, Severi G, Baglietto L, ... ... Herceg Z, et al. DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility. European Journal of Cancer (Oxford, England : 1990). 75: 299-307. PMID 28259012 DOI: 10.1016/J.Ejca.2017.01.014  0.411
2017 Aushev VN, Gammon MD, Parada H, Esposti DD, Hernandez-Vargas H, Herceg Z, Teitelbaum S, Zhu J, Lee E, Chen J. Abstract LB-253: Novel prognostic gene profiles in tumors for breast cancer survival Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-253  0.327
2016 Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, Moreno-Macias H, Smith JA, Brody JA, Dhingra R, Yousefi P, ... ... Herceg Z, et al. Epigenetic Signatures of Cigarette Smoking. Circulation. Cardiovascular Genetics. PMID 27651444 DOI: 10.1161/Circgenetics.116.001506  0.345
2016 Grandin M, Mathot P, Devailly G, Bidet Y, Ghantous A, Favrot C, Gibert B, Gadot N, Puisieux I, Herceg Z, Delcros JG, Bernet A, Mehlen P, Dante R. Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference. Embo Molecular Medicine. PMID 27378792 DOI: 10.15252/Emmm.201505945  0.423
2016 Herceg Z. Epigenetic Mechanisms as an Interface Between the Environment and Genome. Advances in Experimental Medicine and Biology. 903: 3-15. PMID 27343085 DOI: 10.1007/978-1-4899-7678-9_1  0.449
2016 Ardin M, Cahais V, Castells X, Bouaoun L, Byrnes G, Herceg Z, Zavadil J, Olivier M. MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes. Bmc Bioinformatics. 17: 170. PMID 27091472 DOI: 10.1186/S12859-016-1011-Z  0.304
2016 Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, ... ... Herceg Z, et al. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. American Journal of Human Genetics. PMID 27040690 DOI: 10.1016/J.Ajhg.2016.02.019  0.392
2016 Ambatipudi S, Cuenin C, Hernandez-Vargas H, Ghantous A, Calvez-Kelm FL, Kaaks R, Barrdahl M, Boeing H, Aleksandrova K, Trichopoulou A, Lagiou P, Naska A, Palli D, Krogh V, Polidoro S, ... ... Herceg Z, et al. Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study. Epigenomics. PMID 26864933 DOI: 10.2217/Epi-2016-0001  0.373
2016 Vuong T, Mallet JF, Ouzounova M, Rahbar S, Hernandez-Vargas H, Herceg Z, Matar C. Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation. Journal of Translational Medicine. 14: 13. PMID 26762586 DOI: 10.1186/S12967-016-0770-7  0.322
2016 Korenjak M, Huskova H, Ardin M, Zhivagui M, Guyton K, Barupal DK, Straif K, Herceg Z, Olivier M, Hollstein M, Zavadil J. Abstract 5154: Modeling cancer driver-like events in barrier bypass-clonal expansion in vitro assays Cancer Research. 76: 5154-5154. DOI: 10.1158/1538-7445.Am2016-5154  0.403
2016 Holmila R, Sklias A, Muller DC, Esposti DD, Guilloreau P, Mckay J, Sangrajrang S, Srivatanakul P, Hainaut P, Merle P, Costa ANd, Herceg Z. Abstract 4468: Targeted deep sequencing of plasma circulating cell-free DNA shows VIM and FBLN1 methylation as potential biomarkers for hepatocellular carcinoma Cancer Research. 76: 4468-4468. DOI: 10.1158/1538-7445.Am2016-4468  0.391
2016 Kettunen E, Stuopelytė K, Hernandez-Vargas H, Wolff H, Anttila SL, Herceg Z, Jarmalaite S, Husgafvel-Pursiainen K. Abstract 2765: Asbestos exposure-related DNA methylation markers: a validation study in non-small cell lung tumors Cancer Research. 76: 2765-2765. DOI: 10.1158/1538-7445.Am2016-2765  0.398
2016 Herceg Z. Role of early-life exposures on epigenome and cancer susceptibility in childhood and adulthood Toxicology Letters. 259. DOI: 10.1016/J.Toxlet.2016.07.082  0.308
2015 Ancey PB, Testoni B, Gruffaz M, Cros MP, Durand G, Le Calvez-Kelm F, Durantel D, Herceg Z, Hernandez-Vargas H. Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes. Oncotarget. PMID 26565721 DOI: 10.18632/Oncotarget.6270  0.427
2015 Vaca-Paniagua F, Oliver J, Nogueira da Costa A, Merle P, McKay J, Herceg Z, Holmila R. Targeted deep DNA methylation analysis of circulating cell-free DNA in plasma using massively parallel semiconductor sequencing. Epigenomics. 7: 353-62. PMID 26077425 DOI: 10.2217/Epi.14.94  0.444
2015 Kuasne H, Cólus IM, Busso AF, Hernandez-Vargas H, Barros-Filho MC, Marchi FA, Scapulatempo-Neto C, Faria EF, Lopes A, Guimarães GC, Herceg Z, Rogatto SR. Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers. Clinical Epigenetics. 7: 46. PMID 25908946 DOI: 10.1186/S13148-015-0082-4  0.331
2015 Hernandez-Vargas H, Castelino J, Silver MJ, Dominguez-Salas P, Cros MP, Durand G, Calvez-Kelm FL, Prentice AM, Wild CP, Moore SE, Hennig BJ, Herceg Z, Gong YY, Routledge MN. Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia. International Journal of Epidemiology. PMID 25855716 DOI: 10.1093/Ije/Dyv027  0.412
2015 Lambert MP, Ancey PB, Esposti DD, Cros MP, Sklias A, Scoazec JY, Durantel D, Hernandez-Vargas H, Herceg Z. Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors. Clinical Epigenetics. 7: 15. PMID 25755686 DOI: 10.1186/S13148-015-0053-9  0.457
2015 Ghantous A, Hernandez-Vargas H, Byrnes G, Dwyer T, Herceg Z. Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk. Mutagenesis. PMID 25724893 DOI: 10.1093/Mutage/Gev010  0.402
2015 Wild CP, Bucher JR, de Jong BW, Dillner J, von Gertten C, Groopman JD, Herceg Z, Holmes E, Holmila R, Olsen JH, Ringborg U, Scalbert A, Shibata T, Smith MT, Ulrich C, et al. Translational cancer research: balancing prevention and treatment to combat cancer globally. Journal of the National Cancer Institute. 107: 353. PMID 25515230 DOI: 10.1093/Jnci/Dju353  0.338
2015 Beltrami CM, Reis MBd, Barros-Filho MC, Marchi FA, Kuasne H, Ambatipudi S, Herceg Z, Kowalski LP, Rogatto SR. DNA methylation profile in papillary thyroid cancer according to BRAF (V600E) mutation Cancer Research. 1. DOI: 10.1158/1538-7445.Am2015-3829  0.417
2015 Kettunen EM, Hernandez-Vargas H, Cros M, Durand G, Calvez-Kelm FL, Wolff H, Salmenkivi K, Anttila SL, Herceg Z, Husgafvel-Pursiainen K. Abstract 1060: Epigenome-wide DNA methylation profiling of lung tumors from asbestos-exposed patients Cancer Research. 75: 1060-1060. DOI: 10.1158/1538-7445.Am2015-1060  0.43
2014 Lee HS, Barraza-Villarreal A, Biessy C, Duarte-Salles T, Sly PD, Ramakrishnan U, Rivera J, Herceg Z, Romieu I. Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants. Physiological Genomics. 46: 851-7. PMID 25293351 DOI: 10.1152/Physiolgenomics.00061.2014  0.373
2014 Caygill CP, Gatenby PA, Herceg Z, Lima SC, Pinto LF, Watson A, Wu MS. Comparative genomic analysis of esophageal cancers. Annals of the New York Academy of Sciences. 1325: 69-76. PMID 25266016 DOI: 10.1111/Nyas.12524  0.347
2014 Guillot C, Favaudon V, Herceg Z, Sagne C, Sauvaigo S, Merle P, Hall J, Chemin I. PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models. Bmc Cancer. 14: 603. PMID 25139788 DOI: 10.1186/1471-2407-14-603  0.397
2014 Ghantous A, Saffery R, Cros MP, Ponsonby AL, Hirschfeld S, Kasten C, Dwyer T, Herceg Z, Hernandez-Vargas H. Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling. Bmc Biotechnology. 14: 60. PMID 24980254 DOI: 10.1186/1472-6750-14-60  0.393
2014 Martin M, Ancey PB, Cros MP, Durand G, Le Calvez-Kelm F, Hernandez-Vargas H, Herceg Z. Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-β) is associated with a DNA methylome switch. Bmc Genomics. 15: 435. PMID 24898317 DOI: 10.1186/1471-2164-15-435  0.414
2014 Ecsedi S, Hernandez-Vargas H, Lima SC, Vizkeleti L, Toth R, Lazar V, Koroknai V, Kiss T, Emri G, Herceg Z, Adany R, Balazs M. DNA methylation characteristics of primary melanomas with distinct biological behaviour. Plos One. 9: e96612. PMID 24832207 DOI: 10.1371/Journal.Pone.0096612  0.45
2014 Siouda M, Frecha C, Accardi R, Yue J, Cuenin C, Gruffat H, Manet E, Herceg Z, Sylla BS, Tommasino M. Epstein-Barr virus down-regulates tumor suppressor DOK1 expression. Plos Pathogens. 10: e1004125. PMID 24809689 DOI: 10.1371/Journal.Ppat.1004125  0.385
2014 Tapias A, Zhou ZW, Shi Y, Chong Z, Wang P, Groth M, Platzer M, Huttner W, Herceg Z, Yang YG, Wang ZQ. Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions. Cell Stem Cell. 14: 632-43. PMID 24792116 DOI: 10.1016/J.Stem.2014.04.001  0.333
2014 Leduc C, Chemin G, Puget N, Sawan C, Moutahir M, Herceg Z, Khamlichi AA. Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells. Cell Cycle (Georgetown, Tex.). 13: 1583-9. PMID 24675885 DOI: 10.4161/Cc.28560  0.312
2014 Guillot C, Hall J, Herceg Z, Merle P, Chemin I. Update on hepatocellular carcinoma breakthroughs: poly(ADP-ribose) polymerase inhibitors as a promising therapeutic strategy. Clinics and Research in Hepatology and Gastroenterology. 38: 137-42. PMID 23953496 DOI: 10.1016/J.Clinre.2013.07.006  0.316
2014 Lee HS, Herceg Z. The epigenome and cancer prevention: A complex story of dietary supplementation. Cancer Letters. 342: 275-84. PMID 22266189 DOI: 10.1016/J.Canlet.2012.01.021  0.359
2014 Ambatipudi S, Chajes V, Calvez-Kelm FL, Cuenin C, Durand G, Romieu I, Herceg Z. Abstract 386: Epigenome-wide association study to predict breast cancer risk in European Prospective Investigation into Cancer and Nutrition (EPIC) cohort Cancer Research. 74: 386-386. DOI: 10.1158/1538-7445.Am2014-386  0.386
2014 Kuasne H, Colus IMdS, Hernandez-Vargas H, Busso-Lopes AF, Barros-Filho MC, Marchi FA, Scapulatempo-Neto C, Faria EF, Lopes A, Guimaraes GC, Herceg Z, Rogatto SR. Abstract 2242: Comprehensive genome methylation and whole genome expression analysis in penile carcinoma: Uncovering new molecular markers Cancer Research. 74: 2242-2242. DOI: 10.1158/1538-7445.Am2014-2242  0.328
2014 Xu X, Gammon MD, Hernandez-Vargas H, Herceg Z, Wetmur JG, Teitelbaum SL, Bradshaw PT, Neugut AI, Santella RM, Chen J. DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study (FASEB Journal (2012) 26 (2657-2666) DOI: 10.1096/fj.11-197251) Faseb Journal. 28: 2736-2737. DOI: 10.1096/Fj.11-197251Err  0.399
2013 Demetriou CA, Chen J, Polidoro S, van Veldhoven K, Cuenin C, Campanella G, Brennan K, Clavel-Chapelon F, Dossus L, Kvaskoff M, Drogan D, Boeing H, Kaaks R, Risch A, Trichopoulos D, ... ... Herceg Z, et al. Methylome analysis and epigenetic changes associated with menarcheal age. Plos One. 8: e79391. PMID 24278132 DOI: 10.1371/Journal.Pone.0079391  0.434
2013 Gospodinov A, Herceg Z. Chromatin structure in double strand break repair. Dna Repair. 12: 800-10. PMID 23919923 DOI: 10.1016/J.Dnarep.2013.07.006  0.374
2013 Lee HS, Barraza-Villarreal A, Hernandez-Vargas H, Sly PD, Biessy C, Ramakrishnan U, Romieu I, Herceg Z. Modulation of DNA methylation states and infant immune system by dietary supplementation with ω-3 PUFA during pregnancy in an intervention study. The American Journal of Clinical Nutrition. 98: 480-7. PMID 23761484 DOI: 10.3945/Ajcn.112.052241  0.324
2013 Herceg Z, Lambert MP, van Veldhoven K, Demetriou C, Vineis P, Smith MT, Straif K, Wild CP. Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation. Carcinogenesis. 34: 1955-67. PMID 23749751 DOI: 10.1093/Carcin/Bgt212  0.403
2013 Ghantous A, Sinjab A, Herceg Z, Darwiche N. Parthenolide: from plant shoots to cancer roots. Drug Discovery Today. 18: 894-905. PMID 23688583 DOI: 10.1016/J.Drudis.2013.05.005  0.326
2013 Wild CP, Scalbert A, Herceg Z. Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk. Environmental and Molecular Mutagenesis. 54: 480-99. PMID 23681765 DOI: 10.1002/Em.21777  0.343
2013 Aury-Landas J, Bougeard G, Castel H, Hernandez-Vargas H, Drouet A, Latouche JB, Schouft MT, Férec C, Leroux D, Lasset C, Coupier I, Caron O, Herceg Z, Frebourg T, Flaman JM. Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours. European Journal of Human Genetics : Ejhg. 21: 1369-76. PMID 23612572 DOI: 10.1038/Ejhg.2013.68  0.357
2013 Rakosy Z, Ecsedi S, Toth R, Vizkeleti L, Hernandez-Vargas H, Herandez-Vargas H, Lazar V, Emri G, Szatmari I, Herceg Z, Adany R, Balazs M. Integrative genomics identifies gene signature associated with melanoma ulceration. Plos One. 8: e54958. PMID 23383013 DOI: 10.1371/Journal.Pone.0054958  0.354
2013 Sawan C, Hernandez-Vargas H, Murr R, Lopez F, Vaissière T, Ghantous AY, Cuenin C, Imbert J, Wang ZQ, Ren B, Herceg Z. Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells. Stem Cells (Dayton, Ohio). 31: 979-91. PMID 23362228 DOI: 10.1002/Stem.1341  0.331
2013 Genevois AL, Ichim G, Coissieux MM, Lambert MP, Lavial F, Goldschneider D, Jarrosson-Wuilleme L, Lepinasse F, Gouysse G, Herceg Z, Scoazec JY, Tauszig-Delamasure S, Mehlen P. Dependence receptor TrkC is a putative colon cancer tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 110: 3017-22. PMID 23341610 DOI: 10.1073/Pnas.1212333110  0.339
2013 Umer M, Herceg Z. Deciphering the epigenetic code: an overview of DNA methylation analysis methods. Antioxidants & Redox Signaling. 18: 1972-86. PMID 23121567 DOI: 10.1089/ars.2012.4923  0.336
2013 Gospodinov A, Herceg Z. Shaping chromatin for repair. Mutation Research. 752: 45-60. PMID 23085398 DOI: 10.1016/J.Mrrev.2012.10.001  0.394
2013 Genevois A, Ichim G, Coissieux M, Lambert M, Lepinasse F, Herceg Z, Scoazec J, Tauszig-Delamasure S, Mehlen P. Abstract 3036: The dependence receptor TrkC is a putative colon cancer tumor suppressor. Cancer Research. 73: 3036-3036. DOI: 10.1158/1538-7445.Am2013-3036  0.344
2013 Herceg Z. Epigenome changes induced by environmental factors and cancer Toxicology Letters. 221. DOI: 10.1016/J.Toxlet.2013.06.060  0.312
2012 Siouda M, Yue J, Shukla R, Guillermier S, Herceg Z, Creveaux M, Accardi R, Tommasino M, Sylla BS. Transcriptional regulation of the human tumor suppressor DOK1 by E2F1. Molecular and Cellular Biology. 32: 4877-90. PMID 23028047 DOI: 10.1128/Mcb.01050-12  0.383
2012 Nogueira da Costa A, Herceg Z. Detection of cancer-specific epigenomic changes in biofluids: powerful tools in biomarker discovery and application. Molecular Oncology. 6: 704-15. PMID 22925902 DOI: 10.1016/J.Molonc.2012.07.005  0.431
2012 Mahabir S, Aagaard K, Anderson LM, Herceg Z, Hiatt RA, Hoover RN, Linet MS, Medina D, Potischman N, Tretli S, Trichopoulos D, Troisi R. Challenges and opportunities in research on early-life events/exposures and cancer development later in life. Cancer Causes & Control : Ccc. 23: 983-90. PMID 22527169 DOI: 10.1007/S10552-012-9962-5  0.303
2012 Mani S, SzymaÅ„ska K, Cuenin C, Zaridze D, Balassiano K, Lima SC, Matos E, Daudt A, Koifman S, Filho VW, Menezes AM, Curado MP, Ferro G, Vaissière T, Sylla BS, ... ... Herceg Z, et al. DNA methylation changes associated with risk factors in tumors of the upper aerodigestive tract. Epigenetics : Official Journal of the Dna Methylation Society. 7: 270-7. PMID 22430803 DOI: 10.4161/Epi.7.3.19306  0.482
2012 ZoldoÅ¡ V, Horvat T, Novokmet M, Cuenin C, Mužinić A, Pučić M, Huffman JE, Gornik O, PolaÅ¡ek O, Campbell H, Hayward C, Wright AF, Rudan I, Owen K, McCarthy MI, ... Herceg Z, et al. Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome. Epigenetics : Official Journal of the Dna Methylation Society. 7: 164-72. PMID 22395466 DOI: 10.4161/Epi.7.2.18918  0.346
2012 Xu X, Gammon MD, Hernandez-Vargas H, Herceg Z, Wetmur JG, Teitelbaum SL, Bradshaw PT, Neugut AI, Santella RM, Chen J. DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2657-66. PMID 22371529 DOI: 10.1096/Fj.11-197251  0.407
2012 Kaur P, Mani S, Cros MP, Scoazec JY, Chemin I, Hainaut P, Herceg Z. Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 33: 325-36. PMID 22351518 DOI: 10.1007/S13277-012-0331-5  0.402
2012 Martin M, Herceg Z. From hepatitis to hepatocellular carcinoma: a proposed model for cross-talk between inflammation and epigenetic mechanisms. Genome Medicine. 4: 8. PMID 22293089 DOI: 10.1186/Gm307  0.4
2012 Saulnier A, Vaissière T, Yue J, Siouda M, Malfroy M, Accardi R, Creveaux M, Sebastian S, Shahzad N, Gheit T, Hussain I, Torrente M, Maffini FA, Calabrese L, Chiesa F, ... ... Herceg Z, et al. Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers. International Journal of Cancer. Journal International Du Cancer. 130: 2484-94. PMID 21796618 DOI: 10.1002/Ijc.26299  0.414
2011 Herceg Z, Hernandez-Vargas H. New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research. Epigenomics. 3: 383-6. PMID 22126196 DOI: 10.2217/Epi.11.64  0.388
2011 Gospodinov A, Vaissiere T, Krastev DB, Legube G, Anachkova B, Herceg Z. Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection. Molecular and Cellular Biology. 31: 4735-45. PMID 21947284 DOI: 10.1128/Mcb.06182-11  0.743
2011 Lima SC, Hernández-Vargas H, Simão T, Durand G, Kruel CD, Le Calvez-Kelm F, Ribeiro Pinto LF, Herceg Z. Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkers. Epigenetics : Official Journal of the Dna Methylation Society. 6: 1217-27. PMID 21946330 DOI: 10.4161/Epi.6.10.17199  0.486
2011 Balassiano K, Lima S, Jenab M, Overvad K, Tjonneland A, Boutron-Ruault MC, Clavel-Chapelon F, Canzian F, Kaaks R, Boeing H, Meidtner K, Trichopoulou A, Laglou P, Vineis P, Panico S, ... ... Herceg Z, et al. Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Cancer Letters. 311: 85-95. PMID 21831520 DOI: 10.1016/J.Canlet.2011.06.038  0.465
2011 Scoccianti C, Ricceri F, Ferrari P, Cuenin C, Sacerdote C, Polidoro S, Jenab M, Hainaut P, Vineis P, Herceg Z. Methylation patterns in sentinel genes in peripheral blood cells of heavy smokers: Influence of cruciferous vegetables in an intervention study. Epigenetics : Official Journal of the Dna Methylation Society. 6: 1114-9. PMID 21822058 DOI: 10.4161/Epi.6.9.16515  0.413
2011 Herceg Z, Vaissière T. Epigenetic mechanisms and cancer: an interface between the environment and the genome. Epigenetics : Official Journal of the Dna Methylation Society. 6: 804-19. PMID 21758002 DOI: 10.4161/Epi.6.7.16262  0.448
2011 Krais AM, Hautefeuille AH, Cros MP, Krutovskikh V, Tournier JM, Birembaut P, Thépot A, Paliwal A, Herceg Z, Boffetta P, Brennan P, Hainaut PL. CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression. Carcinogenesis. 32: 1388-95. PMID 21586512 DOI: 10.1093/Carcin/Bgr090  0.305
2011 Herceg Z, Paliwal A. Epigenetic mechanisms in hepatocellular carcinoma: how environmental factors influence the epigenome. Mutation Research. 727: 55-61. PMID 21514401 DOI: 10.1016/J.Mrrev.2011.04.001  0.417
2011 Shukla V, Cuenin C, Dubey N, Herceg Z. Loss of histone acetyltransferase cofactor transformation/transcription domain-associated protein impairs liver regeneration after toxic injury. Hepatology (Baltimore, Md.). 53: 954-63. PMID 21319192 DOI: 10.1002/Hep.24120  0.321
2011 Hernandez-Vargas H, Ouzounova M, Le Calvez-Kelm F, Lambert MP, McKay-Chopin S, Tavtigian SV, Puisieux A, Matar C, Herceg Z. Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells. Epigenetics : Official Journal of the Dna Methylation Society. 6: 428-39. PMID 21266853 DOI: 10.4161/Epi.6.4.14515  0.392
2011 Auclair J, Vaissière T, Desseigne F, Lasset C, Bonadona V, Giraud S, Saurin JC, Joly MO, Leroux D, Faivre L, Audoynaud C, Montmain G, Ruano E, Herceg Z, Puisieux A, et al. Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles. Genes, Chromosomes & Cancer. 50: 178-85. PMID 21213371 DOI: 10.1002/Gcc.20842  0.437
2011 Lambert MP, Paliwal A, Vaissière T, Chemin I, Zoulim F, Tommasino M, Hainaut P, Sylla B, Scoazec JY, Tost J, Herceg Z. Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake. Journal of Hepatology. 54: 705-15. PMID 21146512 DOI: 10.1016/J.Jhep.2010.07.027  0.41
2011 Sinčić N, Herceg Z. DNA methylation and cancer: ghosts and angels above the genes. Current Opinion in Oncology. 23: 69-76. PMID 21119515 DOI: 10.1097/Cco.0B013E3283412Eb4  0.519
2011 Vineis P, Chuang SC, Vaissière T, Cuenin C, Ricceri F, Johansson M, Ueland P, Brennan P, Herceg Z. DNA methylation changes associated with cancer risk factors and blood levels of vitamin metabolites in a prospective study. Epigenetics : Official Journal of the Dna Methylation Society. 6: 195-201. PMID 20978370 DOI: 10.4161/Epi.6.2.13573  0.478
2010 Krutovskikh VA, Herceg Z. Oncogenic microRNAs (OncomiRs) as a new class of cancer biomarkers. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 894-904. PMID 21105295 DOI: 10.1002/Bies.201000040  0.33
2010 Min W, Cortes U, Herceg Z, Tong WM, Wang ZQ. Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis. Carcinogenesis. 31: 2058-65. PMID 20926829 DOI: 10.1093/Carcin/Bgq205  0.37
2010 Mani S, Herceg Z. DNA demethylating agents and epigenetic therapy of cancer. Advances in Genetics. 70: 327-40. PMID 20920754 DOI: 10.1016/B978-0-12-380866-0.60012-5  0.46
2010 Sawan C, Herceg Z. Histone modifications and cancer. Advances in Genetics. 70: 57-85. PMID 20920745 DOI: 10.1016/B978-0-12-380866-0.60003-4  0.42
2010 Herceg Z, Ushijima T. Introduction: epigenetics and cancer. Advances in Genetics. 70: 1-23. PMID 20920743 DOI: 10.1016/B978-0-12-380866-0.60001-0  0.372
2010 Kaur P, Paliwal A, Durantel D, Hainaut P, Scoazec JY, Zoulim F, Chemin I, Herceg Z. DNA methylation of hepatitis B virus (HBV) genome associated with the development of hepatocellular carcinoma and occult HBV infection. The Journal of Infectious Diseases. 202: 700-4. PMID 20653444 DOI: 10.1086/655398  0.366
2010 Lima SC, Hernandez-Vargas H, Herceg Z. Epigenetic signatures in cancer: Implications for the control of cancer in the clinic. Current Opinion in Molecular Therapeutics. 12: 316-24. PMID 20521220  0.312
2010 Paliwal A, Vaissière T, Herceg Z. Quantitative detection of DNA methylation states in minute amounts of DNA from body fluids. Methods (San Diego, Calif.). 52: 242-7. PMID 20362673 DOI: 10.1016/J.Ymeth.2010.03.008  0.47
2010 Paliwal A, Vaissière T, Krais A, Cuenin C, Cros MP, Zaridze D, Moukeria A, Boffetta P, Hainaut P, Brennan P, Herceg Z. Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer. Cancer Research. 70: 2779-88. PMID 20332232 DOI: 10.1158/0008-5472.Can-09-4550  0.436
2010 Hernandez-Vargas H, Lambert MP, Le Calvez-Kelm F, Gouysse G, McKay-Chopin S, Tavtigian SV, Scoazec JY, Herceg Z. Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors. Plos One. 5: e9749. PMID 20305825 DOI: 10.1371/Journal.Pone.0009749  0.378
2010 Kirsch-Volders M, Bonassi S, Herceg Z, Hirvonen A, Möller L, Phillips DH. Gender-related differences in response to mutagens and carcinogens. Mutagenesis. 25: 213-21. PMID 20194421 DOI: 10.1093/Mutage/Geq008  0.373
2010 Vaissière T, Herceg Z. Histone code in the cross-talk during DNA damage signaling. Cell Research. 20: 113-5. PMID 20118964 DOI: 10.1038/Cr.2010.14  0.342
2009 Hernandez-Vargas H, Sincic N, Ouzounova M, Herceg Z. Epigenetic signatures in stem cells and cancer stem cells. Epigenomics. 1: 261-80. PMID 22122702 DOI: 10.2217/Epi.09.19  0.333
2009 Loizou JI, Oser G, Shukla V, Sawan C, Murr R, Wang ZQ, Trumpp A, Herceg Z. Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool. Journal of Immunology (Baltimore, Md. : 1950). 183: 6422-31. PMID 19880447 DOI: 10.4049/Jimmunol.0901969  0.317
2009 Herceg Z. Epigenetic information in chromatin and cancer. European Journal of Cancer (Oxford, England : 1990). 45: 442-4. PMID 19775664 DOI: 10.1016/S0959-8049(09)70082-6  0.447
2009 Vaissière T, Cuenin C, Paliwal A, Vineis P, Hoek G, Krzyzanowski M, Airoldi L, Dunning A, Garte S, Hainaut P, Malaveille C, Overvad K, Clavel-Chapelon F, Linseisen J, Boeing H, ... ... Herceg Z, et al. Quantitative analysis of DNA methylation after whole bisulfitome amplification of a minute amount of DNA from body fluids. Epigenetics : Official Journal of the Dna Methylation Society. 4: 221-30. PMID 19458486 DOI: 10.4161/Epi.8833  0.769
2009 Vaissière T, Hung RJ, Zaridze D, Moukeria A, Cuenin C, Fasolo V, Ferro G, Paliwal A, Hainaut P, Brennan P, Tost J, Boffetta P, Herceg Z. Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk factors. Cancer Research. 69: 243-52. PMID 19118009 DOI: 10.1158/0008-5472.Can-08-2489  0.457
2009 Herceg Z, Paliwal A. HBV protein as a double-barrel shot-gun targets epigenetic landscape in liver cancer. Journal of Hepatology. 50: 252-5. PMID 19070919 DOI: 10.1016/J.Jhep.2008.11.013  0.322
2009 Herceg Z. Epigenetic changes in cancer as a signature of exposure to environmental and dietary factors Toxicology Letters. 189. DOI: 10.1016/J.Toxlet.2009.06.006  0.349
2009 Sinčić N, Vlahović M, Herceg Z, Šerman L, Paić F, Katušić A, Bulić-Jakuš F. DNA methylation status during experimental mouse teratocarcinoma development Acta Clinica Croatica. 48: 204.  0.319
2008 Lambert MP, Herceg Z. Epigenetics and cancer, 2nd IARC meeting, Lyon, France, 6 and 7 December 2007. Molecular Oncology. 2: 33-40. PMID 19383327 DOI: 10.1016/J.Molonc.2008.03.005  0.469
2008 Sawan C, Vaissière T, Murr R, Herceg Z. Epigenetic drivers and genetic passengers on the road to cancer. Mutation Research. 642: 1-13. PMID 18471836 DOI: 10.1016/J.Mrfmmm.2008.03.002  0.403
2008 Vaissière T, Sawan C, Herceg Z. Epigenetic interplay between histone modifications and DNA methylation in gene silencing. Mutation Research. 659: 40-8. PMID 18407786 DOI: 10.1016/J.Mrrev.2008.02.004  0.48
2008 Shukla V, Vaissière T, Herceg Z. Histone acetylation and chromatin signature in stem cell identity and cancer. Mutation Research. 637: 1-15. PMID 17850830 DOI: 10.1016/J.Mrfmmm.2007.07.012  0.442
2008 Lambert M, Paliwal A, Vaissière T, Cuenin C, Chemin I, Scoazec J, Hainaut P, Herceg Z. Epigenetic effects of hepatitis B virus and their role in hepatocellular carcinoma European Journal of Cancer Supplements. 6: 197. DOI: 10.1016/S1359-6349(08)71876-7  0.698
2008 Vaissière T, Cuenin C, Hung R, Tost J, Hainaut P, Brennan P, Boffetta P, Herceg Z. DNA methylation signature in lung and head and neck cancer European Journal of Cancer Supplements. 6: 195. DOI: 10.1016/S1359-6349(08)71869-X  0.75
2007 Herceg Z, Hainaut P. Genetic and epigenetic alterations as biomarkers for cancer detection, diagnosis and prognosis. Molecular Oncology. 1: 26-41. PMID 19383285 DOI: 10.1016/J.Molonc.2007.01.004  0.407
2007 Tardat M, Murr R, Herceg Z, Sardet C, Julien E. PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase. The Journal of Cell Biology. 179: 1413-26. PMID 18158331 DOI: 10.1083/Jcb.200706179  0.385
2007 Murr R, Vaissière T, Sawan C, Shukla V, Herceg Z. Orchestration of chromatin-based processes: mind the TRRAP. Oncogene. 26: 5358-72. PMID 17694078 DOI: 10.1038/Sj.Onc.1210605  0.38
2007 Herceg Z. Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors. Mutagenesis. 22: 91-103. PMID 17284773 DOI: 10.1093/Mutage/Gel068  0.447
2006 Yang YG, Saidi A, Frappart PO, Min W, Barrucand C, Dumon-Jones V, Michelon J, Herceg Z, Wang ZQ. Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks. The Embo Journal. 25: 5527-38. PMID 17082765 DOI: 10.1038/Sj.Emboj.7601411  0.36
2006 Loizou JI, Murr R, Finkbeiner MG, Sawan C, Wang ZQ, Herceg Z. Epigenetic information in chromatin: the code of entry for DNA repair. Cell Cycle (Georgetown, Tex.). 5: 696-701. PMID 16582631 DOI: 10.4161/Cc.5.7.2616  0.429
2006 Robert F, Hardy S, Nagy Z, Baldeyron C, Murr R, Déry U, Masson JY, Papadopoulo D, Herceg Z, Tora L. The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair. Molecular and Cellular Biology. 26: 402-12. PMID 16382133 DOI: 10.1128/Mcb.26.2.402-412.2006  0.388
2006 Murr R, Loizou JI, Yang YG, Cuenin C, Li H, Wang ZQ, Herceg Z. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nature Cell Biology. 8: 91-9. PMID 16341205 DOI: 10.1038/Ncb1343  0.363
2005 Yang YG, Herceg Z, Nakanishi K, Demuth I, Piccoli C, Michelon J, Hildebrand G, Jasin M, Digweed M, Wang ZQ. The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells. Carcinogenesis. 26: 1731-40. PMID 15905196 DOI: 10.1093/Carcin/Bgi134  0.374
2005 Herceg Z, Wang ZQ. Rendez-vous at mitosis: TRRAPed in the chromatin. Cell Cycle (Georgetown, Tex.). 4: 383-7. PMID 15711126 DOI: 10.4161/Cc.4.3.1546  0.408
2004 Li H, Cuenin C, Murr R, Wang ZQ, Herceg Z. HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression. The Embo Journal. 23: 4824-34. PMID 15549134 DOI: 10.1038/Sj.Emboj.7600479  0.348
2004 Pétrilli V, Herceg Z, Hassa PO, Patel NS, Di Paola R, Cortes U, Dugo L, Filipe HM, Thiemermann C, Hottiger MO, Cuzzocrea S, Wang ZQ. Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. The Journal of Clinical Investigation. 114: 1072-81. PMID 15489954 DOI: 10.1172/Jci21854  0.33
2004 Demuth I, Frappart PO, Hildebrand G, Melchers A, Lobitz S, Stöckl L, Varon R, Herceg Z, Sperling K, Wang ZQ, Digweed M. An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability. Human Molecular Genetics. 13: 2385-97. PMID 15333589 DOI: 10.1093/Hmg/Ddh278  0.315
2004 Cortes U, Tong WM, Coyle DL, Meyer-Ficca ML, Meyer RG, Petrilli V, Herceg Z, Jacobson EL, Jacobson MK, Wang ZQ. Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice. Molecular and Cellular Biology. 24: 7163-78. PMID 15282315 DOI: 10.1128/Mcb.24.16.7163-7178.2004  0.331
2003 Herceg Z, Li H, Cuenin C, Shukla V, Radolf M, Steinlein P, Wang ZQ. Genome-wide analysis of gene expression regulated by the HAT cofactor Trrap in conditional knockout cells. Nucleic Acids Research. 31: 7011-23. PMID 14627834 DOI: 10.1093/Nar/Gkg902  0.344
2001 Herceg Z, Wang ZQ. Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutation Research. 477: 97-110. PMID 11376691 DOI: 10.1016/S0027-5107(01)00111-7  0.397
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