Will Fischer, Ph.D. - Publications

Los Alamos National Laboratory, Los Alamos, NM, United States 
Molecular evolution, phylogenetics

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Campion SL, Brenna E, Thomson E, Fischer W, Ladell K, McLaren JE, Price DA, Frahm N, McElrath JM, Cohen KW, Maenza JR, Walsh SR, Baden LR, Haynes BF, Korber B, et al. Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial. The Journal of Clinical Investigation. 131. PMID 34850742 DOI: 10.1172/JCI150823  0.329
2020 Stromberg ZR, Fischer W, Bradfute SB, Kubicek-Sutherland JZ, Hraber P. Vaccine Advances against Venezuelan, Eastern, and Western Equine Encephalitis Viruses. Vaccines. 8. PMID 32503232 DOI: 10.3390/Vaccines8020273  0.353
2019 Korber B, Fischer W. T cell-based Strategies for HIV-1 Vaccines. Human Vaccines & Immunotherapeutics. PMID 31584318 DOI: 10.1080/21645515.2019.1666957  0.419
2017 Kijak GH, Sanders-Buell E, Chenine AL, Eller MA, Goonetilleke N, Thomas R, Leviyang S, Harbolick EA, Bose M, Pham P, Oropeza C, Poltavee K, O'Sullivan AM, Billings E, Merbah M, ... ... Fischer W, et al. Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection. Plos Pathogens. 13: e1006510. PMID 28759651 DOI: 10.1371/Journal.Ppat.1006510  0.381
2016 Smith KN, Mailliard RB, Piazza PA, Fischer W, Korber BT, Fecek RJ, Ratner D, Gupta P, Mullins JI, Rinaldo CR. Erratum for Smith et al., Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. Mbio. 7. PMID 27406569 DOI: 10.1128/Mbio.01012-16  0.338
2016 Smith KN, Mailliard RB, Piazza PA, Fischer W, Korber BT, Fecek RJ, Ratner D, Gupta P, Mullins JI, Rinaldo CR. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. Mbio. 7. PMID 27247230 DOI: 10.1128/Mbio.00473-16  0.41
2016 Yusim K, Yoon H, Foley B, Feng S, Macke J, Dimitrijevic M, Abfalterer W, Szinger J, Fischer W, Kuiken C, Korber B. Integrated sequence and immunology filovirus database at Los Alamos. Database : the Journal of Biological Databases and Curation. 2016. PMID 27103629 DOI: 10.1093/Database/Baw047  0.381
2015 Ternette N, Yang H, Partridge T, Llano A, Cedeño S, Fischer R, Charles PD, Dudek NL, Mothe B, Crespo M, Fischer WM, Korber BT, Nielsen M, Borrow P, Purcell AW, et al. Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells. European Journal of Immunology. PMID 26467324 DOI: 10.1002/Eji.201545890  0.323
2014 Kim EY, Lorenzo-Redondo R, Little SJ, Chung YS, Phalora PK, Maljkovic Berry I, Archer J, Penugonda S, Fischer W, Richman DD, Bhattacharya T, Malim MH, Wolinsky SM. Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection. Plos Pathogens. 10: e1004281. PMID 25080100 DOI: 10.1371/Journal.Ppat.1004281  0.387
2014 Campion SL, Brodie TM, Fischer W, Korber BT, Rossetti A, Goonetilleke N, McMichael AJ, Sallusto F. Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors. The Journal of Experimental Medicine. 211: 1273-80. PMID 24958850 DOI: 10.1084/Jem.20130555  0.402
2014 Roederer M, Keele BF, Schmidt SD, Mason RD, Welles HC, Fischer W, Labranche C, Foulds KE, Louder MK, Yang ZY, Todd JP, Buzby AP, Mach LV, Shen L, Seaton KE, et al. Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV. Nature. 505: 502-8. PMID 24352234 DOI: 10.1038/Nature12893  0.436
2013 Yusim K, Dilan R, Borducchi E, Stanley K, Giorgi E, Fischer W, Theiler J, Marcotrigiano J, Korber B, Barouch DH. Hepatitis C genotype 1 mosaic vaccines are immunogenic in mice and induce stronger T-cell responses than natural strains. Clinical and Vaccine Immunology : Cvi. 20: 302-5. PMID 23221002 DOI: 10.1128/Cvi.00605-12  0.353
2012 Fenimore PW, Muhammad MA, Fischer WM, Foley BT, Bakken RR, Thurmond JR, Yusim K, Yoon H, Parker M, Hart MK, Dye JM, Korber B, Kuiken C. Designing and testing broadly-protective filoviral vaccines optimized for cytotoxic T-lymphocyte epitope coverage. Plos One. 7: e44769. PMID 23056184 DOI: 10.1371/Journal.Pone.0044769  0.325
2012 Fischer W, Apetrei C, Santiago ML, Li Y, Gautam R, Pandrea I, Shaw GM, Hahn BH, Letvin NL, Nabel GJ, Korber BT. Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages. Journal of Virology. 86: 13217-31. PMID 23055550 DOI: 10.1128/Jvi.01862-12  0.422
2012 Burgers WA, Manrique A, Masopust D, McKinnon LR, Reynolds MR, Rolland M, Blish C, Chege GK, Curran R, Fischer W, Herrera C, Sather DN. Measurements of immune responses for establishing correlates of vaccine protection against HIV. Aids Research and Human Retroviruses. 28: 641-8. PMID 21861777 DOI: 10.1089/Aid.2011.0239  0.415
2011 Cale EM, Hraber P, Giorgi EE, Fischer W, Bhattacharya T, Leitner T, Yeh WW, Gleasner C, Green LD, Han CS, Korber B, Letvin NL. Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection. Journal of Virology. 85: 3746-57. PMID 21307185 DOI: 10.1128/Jvi.02420-10  0.364
2010 Fischer W, Ganusov VV, Giorgi EE, Hraber PT, Keele BF, Leitner T, Han CS, Gleasner CD, Green L, Lo CC, Nag A, Wallstrom TC, Wang S, McMichael AJ, Haynes BF, et al. Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. Plos One. 5: e12303. PMID 20808830 DOI: 10.1371/Journal.Pone.0012303  0.404
2010 Santra S, Liao HX, Zhang R, Muldoon M, Watson S, Fischer W, Theiler J, Szinger J, Balachandran H, Buzby A, Quinn D, Parks RJ, Tsao CY, Carville A, Mansfield KG, et al. Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys. Nature Medicine. 16: 324-8. PMID 20173754 DOI: 10.1038/Nm.2108  0.454
2010 Barouch DH, O'Brien KL, Simmons NL, King SL, Abbink P, Maxfield LF, Sun YH, La Porte A, Riggs AM, Lynch DM, Clark SL, Backus K, Perry JR, Seaman MS, Carville A, ... ... Fischer W, et al. Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys. Nature Medicine. 16: 319-23. PMID 20173752 DOI: 10.1038/Nm.2089  0.445
2010 Yusim K, Fischer W, Yoon H, Thurmond J, Fenimore PW, Lauer G, Korber B, Kuiken C. Genotype 1 and global hepatitis C T-cell vaccines designed to optimize coverage of genetic diversity. The Journal of General Virology. 91: 1194-206. PMID 20053820 DOI: 10.1099/Vir.0.017491-0  0.417
2009 Kong WP, Wu L, Wallstrom TC, Fischer W, Yang ZY, Ko SY, Letvin NL, Haynes BF, Hahn BH, Korber B, Nabel GJ. Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination. Journal of Virology. 83: 2201-15. PMID 19109395 DOI: 10.1128/Jvi.02256-08  0.463
2009 Fischer W, Apetrei C, Hahn BH, Letvin NL, Nabel GJ, Korber BT. P20-21 LB. Gene-to-gene differences in evolutionary rate between HIV-1 and natural SIV from sooty mangabeys: Implications for vaccine tests in non-human primates Retrovirology. 6: P425. DOI: 10.1186/1742-4690-6-S3-P425  0.421
2009 Fischer W, Keele B, Bhattacharya T, Lo C, Giorgi E, Hraber P, Leitner T, Han C, Gleasner C, Green L, Hahn B, Shaw G, Haynes B, Korber B. P09-21 LB. Deep sequencing of HIV-1 from acute infection: Low initial diversity, and rapid but variable CTL escape Retrovirology. 6: P401. DOI: 10.1186/1742-4690-6-S3-P401  0.342
2009 Yang H, Yan H, Li W, Zhang X, Fischer W, Zhang H, Wu H, Korber BT, McMichael AJ, Xu X, Goonetilleke N. P16-13. A greater breadth of HIV-1-specific T cell responses detected using mosaic peptides compare to consensus peptides Retrovirology. 6: P242. DOI: 10.1186/1742-4690-6-S3-P242  0.39
2008 Thurmond J, Yoon H, Kuiken C, Yusim K, Perkins S, Theiler J, Bhattacharya T, Korber B, Fischer W. Web-based design and evaluation of T-cell vaccine candidates. Bioinformatics (Oxford, England). 24: 1639-40. PMID 18515277 DOI: 10.1093/Bioinformatics/Btn251  0.396
2008 Fischer W, Liao HX, Haynes BF, Letvin NL, Korber B. Coping with viral diversity in HIV vaccine design: a response to Nickle et al. Plos Computational Biology. 4: e15; author reply e2. PMID 18225944 DOI: 10.1371/Journal.Pcbi.0040015  0.44
2007 Frahm N, Kaufmann DE, Yusim K, Muldoon M, Kesmir C, Linde CH, Fischer W, Allen TM, Li B, McMahon BH, Faircloth KL, Hewitt HS, Mackey EW, Miura T, Khatri A, et al. Increased sequence diversity coverage improves detection of HIV-specific T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 179: 6638-50. PMID 17982054 DOI: 10.4049/Jimmunol.179.10.6638  0.403
2007 Timm J, Li B, Daniels MG, Bhattacharya T, Reyor LL, Allgaier R, Kuntzen T, Fischer W, Nolan BE, Duncan J, Schulze zur Wiesch J, Kim AY, Frahm N, Brander C, Chung RT, et al. Human leukocyte antigen-associated sequence polymorphisms in hepatitis C virus reveal reproducible immune responses and constraints on viral evolution. Hepatology (Baltimore, Md.). 46: 339-49. PMID 17559151 DOI: 10.1002/Hep.21702  0.363
2007 Fischer W, Perkins S, Theiler J, Bhattacharya T, Yusim K, Funkhouser R, Kuiken C, Haynes B, Letvin NL, Walker BD, Hahn BH, Korber BT. Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. Nature Medicine. 13: 100-6. PMID 17187074 DOI: 10.1038/Nm1461  0.44
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