Christine Spencer, MS - Publications

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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Robinson PC, Leo PJ, Pointon JJ, Harris J, Cremin K, Bradbury LA, Stebbings S, Harrison AA, Evans DM, Duncan EL, Wordsworth BP, Brown MA. The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis. Genes and Immunity. PMID 26610302 DOI: 10.1038/gene.2015.49  0.52
2015 . Class II HLA interactions modulate genetic risk for multiple sclerosis. Nature Genetics. 47: 1107-13. PMID 26343388 DOI: 10.1038/ng.3395  0.52
2015 Miotto O, Amato R, Ashley EA, MacInnis B, Almagro-Garcia J, Amaratunga C, Lim P, Mead D, Oyola SO, Dhorda M, Imwong M, Woodrow C, Manske M, Stalker J, Drury E, ... ... Spencer CC, et al. Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nature Genetics. 47: 226-34. PMID 25599401 DOI: 10.1038/ng.3189  0.52
2015 Spencer C. From Populations to Clines in Modern Statistical Genetics Population in the Human Sciences: Concepts, Models, Evidence. DOI: 10.1093/acprof:oso/9780199688203.003.0018  0.52
2014 Zhou K, Donnelly L, Yang J, Li M, Deshmukh H, Van Zuydam N, Ahlqvist E, Spencer CC, Groop L, Morris AD, Colhoun HM, Sham PC, McCarthy MI, Palmer CN, et al. Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis. The Lancet. Diabetes & Endocrinology. 2: 481-7. PMID 24731673 DOI: 10.1016/S2213-8587(14)70050-6  0.52
2014 Morris DW, Pearson RD, Cormican P, Kenny EM, O'Dushlaine CT, Perreault LP, Giannoulatou E, Tropea D, Maher BS, Wormley B, Kelleher E, Fahey C, Molinos I, Bellini S, Pirinen M, ... ... Spencer CC, et al. An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis. Human Molecular Genetics. 23: 3316-26. PMID 24474471 DOI: 10.1093/hmg/ddu025  0.52
2013 Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature Genetics. 45: 1353-60. PMID 24076602 DOI: 10.1038/ng.2770  0.52
2013 . Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. Human Molecular Genetics. 22: 4653-60. PMID 23836780 DOI: 10.1093/hmg/ddt293  0.52
2013 Mechelli R, Umeton R, Policano C, Annibali V, Coarelli G, Ricigliano VA, Vittori D, Fornasiero A, Buscarinu MC, Romano S, Salvetti M, Ristori G. A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis. Plos One. 8: e63300. PMID 23696811 DOI: 10.1371/journal.pone.0063300  0.52
2013 Miotto O, Almagro-Garcia J, Manske M, Macinnis B, Campino S, Rockett KA, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Duong S, Nguon C, Chuor CM, Saunders D, ... ... Spencer CC, et al. Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nature Genetics. 45: 648-55. PMID 23624527 DOI: 10.1038/ng.2624  0.52
2013 Fakiola M, Strange A, Cordell HJ, Miller EN, Pirinen M, Su Z, Mishra A, Mehrotra S, Monteiro GR, Band G, Bellenguez C, Dronov S, Edkins S, ... ... Spencer CC, et al. Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nature Genetics. 45: 208-13. PMID 23291585 DOI: 10.1038/ng.2518  0.52
2013 Pirinen M, Donnelly P, Spencer CCA. Efficient computation with a linear mixed model on large-scale data sets with applications to genetic studies Annals of Applied Statistics. 7: 369-390. DOI: 10.1214/12-AOAS586  0.52
2012 Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, Ding J, Li Y, Tejasvi T, Gudjonsson JE, Kang HM, Allen MH, McManus R, Novelli G, Samuelsson L, ... ... Spencer CC, et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nature Genetics. 44: 1341-8. PMID 23143594 DOI: 10.1038/ng.2467  0.52
2012 Bellenguez C, Bevan S, Gschwendtner A, Spencer CC, Burgess AI, Pirinen M, Jackson CA, Traylor M, Strange A, Su Z, Band G, Syme PD, Malik R, et al. Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nature Genetics. 44: 328-33. PMID 22306652 DOI: 10.1038/ng.1081  0.52
2012 Golubchik T, Brueggemann AB, Street T, Gertz RE, Spencer CC, Ho T, Giannoulatou E, Link-Gelles R, Harding RM, Beall B, Peto TE, Moore MR, Donnelly P, Crook DW, Bowden R. Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event. Nature Genetics. 44: 352-5. PMID 22286217 DOI: 10.1038/ng.1072  0.52
2011 Bhatia G, Patterson N, Pasaniuc B, Zaitlen N, Genovese G, Pollack S, Mallick S, Myers S, Tandon A, Spencer C, Palmer CD, Adeyemo AA, Akylbekova EL, Cupples LA, Divers J, et al. Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. American Journal of Human Genetics. 89: 368-81. PMID 21907010 DOI: 10.1016/j.ajhg.2011.07.025  0.52
2011 Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 476: 214-9. PMID 21833088 DOI: 10.1038/nature10251  0.52
2011 Didelot X, Bowden R, Street T, Golubchik T, Spencer C, McVean G, Sangal V, Anjum MF, Achtman M, Falush D, Donnelly P. Recombination and population structure in Salmonella enterica. Plos Genetics. 7: e1002191. PMID 21829375 DOI: 10.1371/journal.pgen.1002191  0.52
2011 Evans DM, Spencer CC, Pointon JJ, Su Z, Harvey D, Kochan G, Oppermann U, Opperman U, Dilthey A, Pirinen M, Stone MA, Appleton L, Moutsianas L, Moutsianis L, Leslie S, et al. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nature Genetics. 43: 761-7. PMID 21743469 DOI: 10.1038/ng.873  0.52
2011 Vukcevic D, Hechter E, Spencer C, Donnelly P. Disease model distortion in association studies Genetic Epidemiology. 35: 278-290. PMID 21416505 DOI: 10.1002/gepi.20576  0.52
2011 Zhou K, Bellenguez C, Spencer CC, Bennett AJ, Coleman RL, Tavendale R, Hawley SA, Donnelly LA, Schofield C, Groves CJ, Burch L, Carr F, Strange A, et al. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nature Genetics. 43: 117-20. PMID 21186350 DOI: 10.1038/ng.735  0.52
2011 Spencer CC, Plagnol V, Strange A, Gardner M, Paisan-Ruiz C, Band G, Barker RA, Bellenguez C, Bhatia K, Blackburn H, Blackwell JM, Bramon E, Brown MA, et al. Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Human Molecular Genetics. 20: 345-53. PMID 21044948 DOI: 10.1093/hmg/ddq469  0.52
2010 Strange A, Capon F, Spencer CC, Knight J, Weale ME, Allen MH, Barton A, Band G, Bellenguez C, Bergboer JG, Blackwell JM, Bramon E, Bumpstead SJ, Casas JP, et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nature Genetics. 42: 985-90. PMID 20953190 DOI: 10.1038/ng.694  0.52
2009 Barrett JC, Lee JC, Lees CW, Prescott NJ, Anderson CA, Phillips A, Wesley E, Parnell K, Zhang H, Drummond H, Nimmo ER, Massey D, Blaszczyk K, Elliott T, ... ... Spencer CC, ... ... Spencer CC, et al. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nature Genetics. 41: 1330-4. PMID 19915572 DOI: 10.1038/ng.483  0.52
2009 Wang AD, Sharp NP, Spencer CC, Tedman-Aucoin K, Agrawal AF. Selection, epistasis, and parent-of-origin effects on deleterious mutations across environments in Drosophila melanogaster. The American Naturalist. 174: 863-74. PMID 19852616 DOI: 10.1086/645088  0.52
2009 Spencer CCA, Su Z, Donnelly P, Marchini J. Designing genome-wide association studies: Sample size, power, imputation, and the choice of genotyping chip Plos Genetics. 5. PMID 19492015 DOI: 10.1371/journal.pgen.1000477  0.52
2009 O'Donovan MC, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, Leung HT, et al. Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2. Molecular Psychiatry. 14: 30-6. PMID 18813210 DOI: 10.1038/mp.2008.108  0.52
2008 O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nature Genetics. 40: 1053-5. PMID 18677311 DOI: 10.1038/ng.201  0.52
2008 Le Gac M, Brazas MD, Bertrand M, Tyerman JG, Spencer CC, Hancock RE, Doebeli M. Metabolic changes associated with adaptive diversification in Escherichia coli. Genetics. 178: 1049-60. PMID 18245349 DOI: 10.1534/genetics.107.082040  0.52
2008 Tyerman JG, Bertrand M, Spencer CC, Doebeli M. Experimental demonstration of ecological character displacement. Bmc Evolutionary Biology. 8: 34. PMID 18234105 DOI: 10.1186/1471-2148-8-34  0.52
2008 Spencer CC, Tyerman J, Bertrand M, Doebeli M. Adaptation increases the likelihood of diversification in an experimental bacterial lineage. Proceedings of the National Academy of Sciences of the United States of America. 105: 1585-9. PMID 18216261 DOI: 10.1073/pnas.0708504105  0.52
2007 Nejentsev S, Howson JM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M, King E, Masters J, Hulme J, Maier LM, Smyth D, Bailey R, Cooper JD, et al. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature. 450: 887-92. PMID 18004301 DOI: 10.1038/nature06406  0.52
2007 Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donnelly P, Barrett JC, ... ... Spencer CC, et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nature Genetics. 39: 1329-37. PMID 17952073 DOI: 10.1038/ng.2007.17  0.52
2007 Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand WH, Samani NJ, Todd JA, Donnelly P, Barrett JC, Davison D, Easton D, ... ... Spencer CCA, et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Nature. 447: 661-678. PMID 17554300 DOI: 10.1038/nature05911  0.52
2007 Spencer CC, Bertrand M, Travisano M, Doebeli M. Adaptive diversification in genes that regulate resource use in Escherichia coli. Plos Genetics. 3: e15. PMID 17238290 DOI: 10.1371/journal.pgen.0030015  0.52
2007 Spencer CC, Saxer G, Travisano M, Doebeli M. Seasonal resource oscillations maintain diversity in bacterial microcosms Evolutionary Ecology Research. 9: 775-787.  0.52
2006 Spencer CC, Deloukas P, Hunt S, Mullikin J, Myers S, Silverman B, Donnelly P, Bentley D, McVean G. The influence of recombination on human genetic diversity. Plos Genetics. 2: e148. PMID 17044736 DOI: 10.1371/journal.pgen.0020148  0.52
2006 McVean G, Spencer CC. Scanning the human genome for signals of selection Current Opinion in Genetics and Development. 16: 624-629. PMID 17008091 DOI: 10.1016/j.gde.2006.09.004  0.52
2006 Spencer CCA. Human polymorphism around recombination hotspots Biochemical Society Transactions. 34: 535-536. PMID 16856853 DOI: 10.1042/BST0340535  0.52
2006 Myers S, Spencer CCA, Auton A, Bottolo L, Freeman C, Donnelly P, McVean G. The distribution and causes of meiotic recombination in the human genome Biochemical Society Transactions. 34: 526-530. PMID 16856851 DOI: 10.1042/BST0340526  0.52
2006 Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K, Spencer CC, Jones MC, Gillson C, Searle S, Zhou Y, Kokocinski F, et al. The DNA sequence and biological annotation of human chromosome 1. Nature. 441: 315-21. PMID 16710414 DOI: 10.1038/nature04727  0.52
2006 Hanchard NA, Rockett KA, Spencer C, Coop G, Pinder M, Jallow M, Kimber M, McVean G, Mott R, Kwiatkowski DP. Screening for recently selected alleles by analysis of human haplotype similarity. American Journal of Human Genetics. 78: 153-9. PMID 16385459 DOI: 10.1086/499252  0.52
2005 Spencer CC, Promislow DE. Age-specific changes in epistatic effects on mortality rate in Drosophila melanogaster. The Journal of Heredity. 96: 513-21. PMID 15958798 DOI: 10.1093/jhered/esi071  0.52
2005 McVean G, Spencer CCA, Chaix R. Perspectives on human genetic variation from the HapMap project Plos Genetics. 1: 0413-0418. DOI: 10.1371/journal.pgen.0010054  0.52
2004 Spencer CC, Coop G. SelSim: a program to simulate population genetic data with natural selection and recombination. Bioinformatics (Oxford, England). 20: 3673-5. PMID 15271777 DOI: 10.1093/bioinformatics/bth417  0.52
2003 Spencer CC, Howell CE, Wright AR, Promislow DE. Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background. Aging Cell. 2: 123-30. PMID 12882325  0.52
2000 Spencer CC, Neigel JE, Leberg PL. Experimental evaluation of the usefulness of microsatellite DNA for detecting demographic bottlenecks. Molecular Ecology. 9: 1517-28. PMID 11050547 DOI: 10.1046/j.1365-294X.2000.01031.x  0.52
1999 Spencer CC, Chlan CA, Neigel JE, Scribner KT, Wooten MC, Leberg PL. Polymorphic microsatellite markers in the western mosquitofish, Gambusia affinis. Molecular Ecology. 8: 157-8. PMID 9919704  0.52
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