Andy Y. Shih, Ph.D. - Publications

Affiliations: 
Neurophysics University of California, San Diego, La Jolla, CA 
Area:
Vascular system

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sosa MJ, Shih AY, Bonney SK. The elusive brain perivascular fibroblast: a potential role in vascular stability and homeostasis. Frontiers in Cardiovascular Medicine. 10: 1283434. PMID 38075961 DOI: 10.3389/fcvm.2023.1283434  0.325
2023 Bonney SK, Nielson CD, Sosa MJ, Shih AY. Capillary regression leads to sustained local hypoperfusion by inducing constriction of upstream transitional vessels. Biorxiv : the Preprint Server For Biology. PMID 37961686 DOI: 10.1101/2023.10.28.564529  0.341
2023 Jones HE, Coelho-Santos V, Bonney SK, Abrams KA, Shih AY, Siegenthaler JA. Meningeal origins and dynamics of perivascular fibroblast development on the mouse cerebral vasculature. Development (Cambridge, England). 150. PMID 37756588 DOI: 10.1242/dev.201805  0.384
2023 Ighodaro ET, Shahidehpour RK, Bachstetter AD, Abner EL, Nelson RS, Fardo DW, Shih AY, Grant RI, Neltner JH, Schmitt FA, Jicha GA, Kryscio RJ, Wilcock DM, Van Eldik LJ, Nelson PT. A neuropathologic feature of brain aging: multi-lumen vascular profiles. Acta Neuropathologica Communications. 11: 138. PMID 37641147 DOI: 10.1186/s40478-023-01638-2  0.786
2023 Sargent SM, Bonney SK, Li Y, Stamenkovic S, Takeno M, Coelho-Santos V, Shih AY. Endothelial structure contributes to heterogeneity in brain capillary diameter. Vascular Biology (Bristol, England). PMID 37582180 DOI: 10.1530/VB-23-0010  0.389
2023 Sargent SM, Bonney SK, Li Y, Stamenkovic S, Takeno M, Coelho-Santos V, Shih AY. Endothelial structure contributes to heterogeneity in brain capillary diameter. Biorxiv : the Preprint Server For Biology. PMID 37163126 DOI: 10.1101/2023.04.26.538503  0.379
2023 Jones HE, Coelho-Santos V, Bonney SK, Abrams KA, Shih AY, Siegenthaler JA. Meningeal origins and dynamics of perivascular fibroblast development on the mouse cerebral vasculature. Biorxiv : the Preprint Server For Biology. PMID 36993587 DOI: 10.1101/2023.03.23.533982  0.385
2022 Berthiaume AA, Schmid F, Stamenkovic S, Coelho-Santos V, Nielson CD, Weber B, Majesky MW, Shih AY. Pericyte remodeling is deficient in the aged brain and contributes to impaired capillary flow and structure. Nature Communications. 13: 5912. PMID 36207315 DOI: 10.1038/s41467-022-33464-w  0.828
2022 O'Herron PJ, Hartmann DA, Xie K, Kara P, Shih AY. 3D optogenetic control of arteriole diameter in vivo. Elife. 11. PMID 36107146 DOI: 10.7554/eLife.72802  0.764
2022 Nielson CD, Berthiaume AA, Bonney SK, Shih AY. Corrigendum: Single Cell Optical Ablation of Brain Pericytes. Frontiers in Neuroscience. 16: 974311. PMID 35911985 DOI: 10.3389/fnins.2022.974311  0.794
2022 Nielson CD, Shih AY. Single Cell Optical Ablation of Brain Pericytes. Frontiers in Neuroscience. 16: 900761. PMID 35720702 DOI: 10.3389/fnins.2022.900761  0.42
2022 Coelho-Santos V, Tieu T, Shih AY. Reinforced thinned-skull window for repeated imaging of the neonatal mouse brain. Neurophotonics. 9: 031918. PMID 35673538 DOI: 10.1117/1.NPh.9.3.031918  0.374
2022 Faulhaber LD, D'Costa O, Shih AY, Gust J. Antibody-based leukocyte label for two-photon brain imaging in mice. Neurophotonics. 9: 031917. PMID 35637871 DOI: 10.1117/1.NPh.9.3.031917  0.655
2022 Bonney SK, Coelho-Santos V, Huang SF, Takeno M, Kornfeld J, Keller A, Shih AY. Public Volume Electron Microscopy Data: An Essential Resource to Study the Brain Microvasculature. Frontiers in Cell and Developmental Biology. 10: 849469. PMID 35450291 DOI: 10.3389/fcell.2022.849469  0.375
2021 Faulhaber LD, Phuong AQ, Hartsuyker KJ, Cho Y, Mand KK, Harper SD, Olson AK, Garden GA, Shih AY, Gust J. Brain capillary obstruction during neurotoxicity in a mouse model of anti-CD19 chimeric antigen receptor T-cell therapy. Brain Communications. 4: fcab309. PMID 35169706 DOI: 10.1093/braincomms/fcab309  0.671
2021 Bonney SK, Sullivan LT, Cherry TJ, Daneman R, Shih AY. Distinct features of brain perivascular fibroblasts and mural cells revealed by two-photon imaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211068528. PMID 34929105 DOI: 10.1177/0271678X211068528  0.359
2021 Hartmann DA, Coelho-Santos V, Shih AY. Pericyte Control of Blood Flow Across Microvascular Zones in the Central Nervous System. Annual Review of Physiology. PMID 34672718 DOI: 10.1146/annurev-physiol-061121-040127  0.75
2021 Coelho-Santos V, Berthiaume AA, Ornelas S, Stuhlmann H, Shih AY. Imaging the construction of capillary networks in the neonatal mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34172585 DOI: 10.1073/pnas.2100866118  0.835
2021 Ornelas S, Berthiaume AA, Bonney SK, Coelho-Santos V, Underly RG, Kremer A, Guérin CJ, Lippens S, Shih AY. Three-dimensional ultrastructure of the brain pericyte-endothelial interface. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211012836. PMID 33970018 DOI: 10.1177/0271678X211012836  0.789
2021 McDowell KP, Berthiaume AA, Tieu T, Hartmann DA, Shih AY. VasoMetrics: unbiased spatiotemporal analysis of microvascular diameter in multi-photon imaging applications. Quantitative Imaging in Medicine and Surgery. 11: 969-982. PMID 33654670 DOI: 10.21037/qims-20-920  0.806
2021 Hartmann DA, Berthiaume AA, Grant RI, Harrill SA, Koski T, Tieu T, McDowell KP, Faino AV, Kelly AL, Shih AY. Brain capillary pericytes exert a substantial but slow influence on blood flow. Nature Neuroscience. PMID 33603231 DOI: 10.1038/s41593-020-00793-2  0.822
2020 Underly RG, Shih AY. Rapid, Nitric Oxide Synthesis-Dependent Activation of MMP-9 at Pericyte Somata During Capillary Ischemia . Frontiers in Physiology. 11: 619230. PMID 33505320 DOI: 10.3389/fphys.2020.619230  0.799
2020 Watson AN, Berthiaume AA, Faino AV, McDowell KP, Bhat NR, Hartmann DA, Shih AY. Mild pericyte deficiency is associated with aberrant brain microvascular flow in aged PDGFRβ mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19900543. PMID 31987006 DOI: 10.1177/0271678X19900543  0.775
2019 Coelho-Santos V, Shih AY. Postnatal development of cerebrovascular structure and the neurogliovascular unit. Wiley Interdisciplinary Reviews. Developmental Biology. e363. PMID 31576670 DOI: 10.1002/wdev.363  0.36
2019 Berthiaume AA, Shih AY. Sharpening the tools for pericyte research. Nature Neuroscience. 22: 1041-1043. PMID 31235904 DOI: 10.1038/S41593-019-0437-9  0.803
2018 Berthiaume AA, Hartmann DA, Majesky MW, Bhat NR, Shih AY. Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis. Frontiers in Aging Neuroscience. 10: 210. PMID 30065645 DOI: 10.3389/Fnagi.2018.00210  0.811
2018 Shih AY, Hyacinth HI, Hartmann DA, van Veluw SJ. Rodent Models of Cerebral Microinfarct and Microhemorrhage. Stroke. PMID 29459393 DOI: 10.1161/Strokeaha.117.016995  0.742
2018 Berthiaume AA, Grant RI, McDowell KP, Underly RG, Hartmann DA, Levy M, Bhat NR, Shih AY. Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain. Cell Reports. 22: 8-16. PMID 29298435 DOI: 10.1016/J.Celrep.2017.12.016  0.79
2017 Mateo C, Knutsen PM, Tsai PS, Shih AY, Kleinfeld D. Entrainment of Arteriole Vasomotor Fluctuations by Neural Activity Is a Basis of Blood-Oxygenation-Level-Dependent "Resting-State" Connectivity. Neuron. PMID 29107517 DOI: 10.1016/J.Neuron.2017.10.012  0.704
2017 Hartmann DA, Hyacinth HI, Liao FF, Shih AY. Does pathology of small venules contribute to cerebral microinfarcts and dementia? Journal of Neurochemistry. PMID 28950410 DOI: 10.1111/Jnc.14228  0.766
2017 Grant RI, Hartmann DA, Underly RG, Berthiaume AA, Bhat NR, Shih AY. Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17732229. PMID 28933255 DOI: 10.1177/0271678X17732229  0.776
2017 Hyacinth HI, Sugihara CL, Spencer TL, Archer DR, Shih AY. Higher prevalence of spontaneous cerebral vasculopathy and cerebral infarcts in a mouse model of sickle cell disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17732275. PMID 28925802 DOI: 10.1177/0271678X17732275  0.414
2017 Underly RG, Shih AY. Photothrombotic Induction of Capillary Ischemia in the Mouse Cortex during in vivo Two-photon Imaging. Bio-Protocol. 7. PMID 28835908 DOI: 10.21769/BioProtoc.2378  0.812
2017 van Veluw SJ, Shih AY, Smith EE, Chen C, Schneider JA, Wardlaw JM, Greenberg SM, Biessels GJ. Detection, risk factors, and functional consequences of cerebral microinfarcts. The Lancet. Neurology. PMID 28716371 DOI: 10.1016/S1474-4422(17)30196-5  0.38
2017 Summers PM, Hartmann DA, Hui ES, Nie X, Deardorff RL, McKinnon ET, Helpern JA, Jensen JH, Shih AY. Functional deficits induced by cortical microinfarcts. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X16685573. PMID 28090802 DOI: 10.1177/0271678X16685573  0.811
2017 Underly RG, Levy M, Hartmann DA, Grant RI, Watson AN, Shih AY. Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during Ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 129-140. PMID 28053036 DOI: 10.1523/Jneurosci.2891-16.2016  0.789
2017 Shih A, Hartmann DA. In vivo Optical Imaging and Manipulation of Pericytes in the Mouse Brain Brain. DOI: 10.1364/Brain.2017.Brw3B.1  0.766
2015 Taylor ZJ, Hui ES, Watson AN, Nie X, Deardorff RL, Jensen JH, Helpern JA, Shih AY. Microvascular basis for growth of small infarcts following occlusion of single penetrating arterioles in mouse cortex. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661182 DOI: 10.1177/0271678X15608388  0.823
2015 Hartmann DA, Underly RG, Grant RI, Watson AN, Lindner V, Shih AY. Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice. Neurophotonics. 2: 041402. PMID 26158016 DOI: 10.1117/1.Nph.2.4.041402  0.793
2015 Shih AY, Rühlmann C, Blinder P, Devor A, Drew PJ, Friedman B, Knutsen PM, Lyden PD, Matéo C, Mellander L, Nishimura N, Schaffer CB, Tsai PS, Kleinfeld D. Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture. Microcirculation (New York, N.Y. : 1994). 22: 204-18. PMID 25705966 DOI: 10.1111/Micc.12195  0.8
2015 Hartmann DA, Underly RG, Watson AN, Shih AY. A murine toolbox for imaging the neurovascular unit. Microcirculation (New York, N.Y. : 1994). 22: 168-82. PMID 25352367 DOI: 10.1111/Micc.12176  0.806
2014 Summers PM, Taylor ZJ, Shih AY. Two-photon imaging of cerebral vasodynamics in awake mice during health and disease Advances in Intravital Microscopy: From Basic to Clinical Research. 25-43. DOI: 10.1007/978-94-017-9361-2_2  0.656
2014 Shih AY, Driscoll JD, Pesavento MJ, Kleinfeld D. Two-photon microscopy to measure blood flow and concurrent brain cell activity Neuromethods. 85: 273-290. DOI: 10.1007/978-1-62703-785-3_16  0.814
2014 Shih AY, Drew PJ, Kleinfeld D. Imaging vasodynamics in the Awake mouse brain with two-photon microscopy Neuromethods. 88: 55-73. DOI: 10.1007/978-1-4939-0724-3_4  0.699
2013 Taylor ZJ, Shih AY. Targeted Occlusion of Individual Pial Vessels of Mouse Cortex. Bio-Protocol. 3. PMID 27547784  0.633
2013 Shih AY, Nishimura N, Nguyen J, Friedman B, Lyden PD, Schaffer CB, Kleinfeld D. Optically induced occlusion of single blood vessels in rodent neocortex. Cold Spring Harbor Protocols. 2013: 1153-60. PMID 24298038 DOI: 10.1101/Pdb.Prot079509  0.776
2013 Driscoll JD, Shih AY, Drew PJ, Cauwenberghs G, Kleinfeld D. Two-photon imaging of blood flow in the rat cortex. Cold Spring Harbor Protocols. 2013: 759-67. PMID 23906919 DOI: 10.1101/Pdb.Prot076513  0.829
2013 Shih AY, Blinder P, Tsai PS, Friedman B, Stanley G, Lyden PD, Kleinfeld D. The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Nature Neuroscience. 16: 55-63. PMID 23242312 DOI: 10.1038/Nn.3278  0.79
2012 Shih AY, Mateo C, Drew PJ, Tsai PS, Kleinfeld D. A polished and reinforced thinned-skull window for long-term imaging of the mouse brain. Journal of Visualized Experiments : Jove. PMID 22433225 DOI: 10.3791/3742  0.796
2012 Shih AY, Driscoll JD, Drew PJ, Nishimura N, Schaffer CB, Kleinfeld D. Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1277-309. PMID 22293983 DOI: 10.1038/Jcbfm.2012.177  0.838
2011 Kleinfeld D, Blinder P, Drew PJ, Driscoll JD, Muller A, Tsai PS, Shih AY. A guide to delineate the logic of neurovascular signaling in the brain. Frontiers in Neuroenergetics. 3: 1. PMID 21559095 DOI: 10.3389/Fnene.2011.00001  0.786
2011 Drew PJ, Shih AY, Kleinfeld D. Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity. Proceedings of the National Academy of Sciences of the United States of America. 108: 8473-8. PMID 21536897 DOI: 10.1073/Pnas.1100428108  0.725
2011 Driscoll JD, Shih AY, Iyengar S, Field JJ, White GA, Squier JA, Cauwenberghs G, Kleinfeld D. Photon counting, censor corrections, and lifetime imaging for improved detection in two-photon microscopy. Journal of Neurophysiology. 105: 3106-13. PMID 21471395 DOI: 10.1152/Jn.00649.2010  0.767
2010 Drew PJ, Shih AY, Driscoll JD, Knutsen PM, Blinder P, Davalos D, Akassoglou K, Tsai PS, Kleinfeld D. Chronic optical access through a polished and reinforced thinned skull. Nature Methods. 7: 981-4. PMID 20966916 DOI: 10.1038/Nmeth.1530  0.805
2010 Blinder P, Shih AY, Rafie C, Kleinfeld D. Topological basis for the robust distribution of blood to rodent neocortex. Proceedings of the National Academy of Sciences of the United States of America. 107: 12670-5. PMID 20616030 DOI: 10.1073/Pnas.1007239107  0.796
2010 Valmianski I, Shih AY, Driscoll JD, Matthews DW, Freund Y, Kleinfeld D. Automatic identification of fluorescently labeled brain cells for rapid functional imaging. Journal of Neurophysiology. 104: 1803-11. PMID 20610792 DOI: 10.1152/Jn.00484.2010  0.794
2010 Drew PJ, Blinder P, Cauwenberghs G, Shih AY, Kleinfeld D. Rapid determination of particle velocity from space-time images using the Radon transform. Journal of Computational Neuroscience. 29: 5-11. PMID 19459038 DOI: 10.1007/S10827-009-0159-1  0.781
2010 Devor A, Shih AY, Tsai PS, Blinder P, Tian P, Teng IC, Kleinfeld D. Two-photon laser scanning microscopy as a tool to study cortical vasodynamics under normal and ischemic conditions Imaging the Brain With Optical Methods. 245-261. DOI: 10.1007/978-1-4419-0452-2_11  0.761
2009 Weidemann A, Kerdiles YM, Knaup KX, Rafie CA, Boutin AT, Stockmann C, Takeda N, Scadeng M, Shih AY, Haase VH, Simon MC, Kleinfeld D, Johnson RS. The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. The Journal of Clinical Investigation. 119: 3373-83. PMID 19809162 DOI: 10.1172/Jci39378  0.56
2009 Friedman B, Schachtrup C, Tsai PS, Shih AY, Akassoglou K, Kleinfeld D, Lyden PD. Acute vascular disruption and aquaporin 4 loss after stroke. Stroke; a Journal of Cerebral Circulation. 40: 2182-90. PMID 19372455 DOI: 10.1161/Strokeaha.108.523720  0.645
2009 Shih AY, Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D. Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 738-51. PMID 19174826 DOI: 10.1038/Jcbfm.2008.166  0.778
2009 Tsai PS, Blinder P, Drew P, Driscoll J, Jeong D, Kaufhold JP, Shih A, Valmianski I, Kleinfeld D. Topology, dynamics, and control in cortical blood flow elucidated with optical techniques Proceedings of Spie - the International Society For Optical Engineering. 7397. DOI: 10.1117/12.829588  0.797
2009 Kleinfeld D, Friedman B, Lyden PD, Shih AY. Targeted occlusion to surface and deep vessels in neocortex via linear and nonlinear optical absorption Animal Models of Acute Neurological Injuries. 169-185. DOI: 10.1007/978-1-60327-185-1_14  0.452
2007 Shih AY, Erb H, Murphy TH. Dopamine activates Nrf2-regulated neuroprotective pathways in astrocytes and meningeal cells. Journal of Neurochemistry. 101: 109-19. PMID 17394461 DOI: 10.1111/J.1471-4159.2006.04345.X  0.529
2007 Pacchioni AM, Vallone J, Melendez RI, Shih A, Murphy TH, Kalivas PW. Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity. Brain Research. 1127: 26-35. PMID 17113054 DOI: 10.1016/J.Brainres.2006.10.036  0.499
2006 Shih AY, Erb H, Sun X, Toda S, Kalivas PW, Murphy TH. Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10514-23. PMID 17035536 DOI: 10.1523/Jneurosci.3178-06.2006  0.592
2006 Sun X, Shih AY, Johannssen HC, Erb H, Li P, Murphy TH. Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface. The Journal of Biological Chemistry. 281: 17420-31. PMID 16624809 DOI: 10.1074/Jbc.M601567200  0.628
2005 Shih AY, Li P, Murphy TH. A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10321-35. PMID 16267240 DOI: 10.1523/Jneurosci.4014-05.2005  0.568
2005 Shih AY, Imbeault S, Barakauskas V, Erb H, Jiang L, Li P, Murphy TH. Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. The Journal of Biological Chemistry. 280: 22925-36. PMID 15840590 DOI: 10.1074/Jbc.M414635200  0.523
2003 Lee JM, Shih AY, Murphy TH, Johnson JA. NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. The Journal of Biological Chemistry. 278: 37948-56. PMID 12842875 DOI: 10.1074/Jbc.M305204200  0.511
2003 Shih AY, Johnson DA, Wong G, Kraft AD, Jiang L, Erb H, Johnson JA, Murphy TH. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3394-406. PMID 12716947 DOI: 10.1523/Jneurosci.23-08-03394.2003  0.514
2001 Shih AY, Murphy TH. xCt cystine transporter expression in HEK293 cells: pharmacology and localization. Biochemical and Biophysical Research Communications. 282: 1132-7. PMID 11302733 DOI: 10.1006/Bbrc.2001.4703  0.504
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