Molly Przeworski - Publications

Affiliations: 
Human Genetics University of Chicago, Chicago, IL 
 Biological Sciences Columbia University, New York, NY 
Area:
Population Genetics
Website:
https://biology.columbia.edu/people/przeworski

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Milligan WR, Fuller ZL, Agarwal I, Eisen MB, Przeworski M, Sella G. Impact of essential workers in the context of social distancing for epidemic control. Plos One. 16: e0255680. PMID 34347855 DOI: 10.1371/journal.pone.0255680  1
2021 Harpak A, Przeworski M. The evolution of group differences in changing environments. Plos Biology. 19: e3001072. PMID 33493148 DOI: 10.1371/journal.pbio.3001072  1
2020 Wu FL, Strand AI, Cox LA, Ober C, Wall JD, Moorjani P, Przeworski M. A comparison of humans and baboons suggests germline mutation rates do not track cell divisions. Plos Biology. 18: e3000838. PMID 32804933 DOI: 10.1371/Journal.Pbio.3000838  1
2020 Fuller ZL, Mocellin VJL, Morris LA, Cantin N, Shepherd J, Sarre L, Peng J, Liao Y, Pickrell J, Andolfatto P, Matz M, Bay LK, Przeworski M. Population genetics of the coral : Toward genomic prediction of bleaching. Science (New York, N.Y.). 369. PMID 32675347 DOI: 10.1126/Science.Aba4674  1
2020 Mostafavi H, Harpak A, Agarwal I, Conley D, Pritchard JK, Przeworski M. Variable prediction accuracy of polygenic scores within an ancestry group. Elife. 9. PMID 31999256 DOI: 10.7554/Elife.48376  1
2019 Young AI, Benonisdottir S, Przeworski M, Kong A. Deconstructing the sources of genotype-phenotype associations in humans. Science (New York, N.Y.). 365: 1396-1400. PMID 31604265 DOI: 10.1126/Science.Aax3710  0.04
2019 Sasani TA, Pedersen BS, Gao Z, Baird L, Przeworski M, Jorde LB, Quinlan AR. Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation. Elife. 8. PMID 31549960 DOI: 10.7554/Elife.46922  1
2019 Agarwal I, Przeworski M. Signatures of replication timing, recombination, and sex in the spectrum of rare variants on the human X chromosome and autosomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31427530 DOI: 10.1073/Pnas.1900714116  1
2019 Gao Z, Moorjani P, Sasani TA, Pedersen BS, Quinlan AR, Jorde LB, Amster G, Przeworski M. Overlooked roles of DNA damage and maternal age in generating human germline mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019089 DOI: 10.1073/Pnas.1901259116  1
2019 Fuller ZL, Berg JJ, Mostafavi H, Sella G, Przeworski M. Measuring intolerance to mutation in human genetics. Nature Genetics. PMID 30962618 DOI: 10.1038/S41588-019-0383-1  1
2019 Mostafavi H, Harpak A, Agarwal I, Conley D, Pritchard JK, Przeworski M. Author response: Variable prediction accuracy of polygenic scores within an ancestry group Elife. DOI: 10.7554/Elife.48376.Sa2  1
2019 Sasani TA, Pedersen BS, Gao Z, Baird L, Przeworski M, Jorde LB, Quinlan AR. Author response: Large, three-generation human families reveal post-zygotic mosaicism and variability in germline mutation accumulation Elife. DOI: 10.7554/Elife.46922.027  1
2018 Amorim CEG, Gao Z, Baker Z, Diesel JF, Simons YB, Haque IS, Pickrell J, Przeworski M. Correction: The population genetics of human disease: The case of recessive, lethal mutations. Plos Genetics. 14: e1007499. PMID 29965964 DOI: 10.1371/Journal.Pgen.1007499  1
2018 Schumer M, Xu C, Powell DL, Durvasula A, Skov L, Holland C, Blazier JC, Sankararaman S, Andolfatto P, Rosenthal GG, Przeworski M. Natural selection interacts with recombination to shape the evolution of hybrid genomes. Science (New York, N.Y.). PMID 29674434 DOI: 10.1126/Science.Aar3684  1
2017 Amorim CEG, Gao Z, Baker Z, Diesel JF, Simons YB, Haque IS, Pickrell J, Przeworski M. The population genetics of human disease: The case of recessive, lethal mutations. Plos Genetics. 13: e1006915. PMID 28957316 DOI: 10.1371/journal.pgen.1006915  1
2017 Mostafavi H, Berisa T, Day FR, Perry JRB, Przeworski M, Pickrell JK. Identifying genetic variants that affect viability in large cohorts. Plos Biology. 15: e2002458. PMID 28873088 DOI: 10.1371/Journal.Pbio.2002458  1
2017 Chen C, Qi H, Shen Y, Pickrell J, Przeworski M. Contrasting Determinants of Mutation Rates in Germline and Soma. Genetics. PMID 28733365 DOI: 10.1534/Genetics.117.1114  1
2017 Baker Z, Schumer M, Haba Y, Bashkirova L, Holland C, Rosenthal GG, Przeworski M. Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates. Elife. 6. PMID 28590247 DOI: 10.7554/Elife.24133  1
2017 Baker Z, Schumer M, Haba Y, Bashkirova L, Holland C, Rosenthal GG, Przeworski M. Author response: Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates Elife. DOI: 10.7554/Elife.24133.040  1
2016 Moorjani P, Gao Z, Przeworski M. Human Germline Mutation and the Erratic Evolutionary Clock. Plos Biology. 14: e2000744. PMID 27760127 DOI: 10.1371/journal.pbio.2000744  1
2016 Moorjani P, Amorim CE, Arndt PF, Przeworski M. Variation in the molecular clock of primates. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601674 DOI: 10.1073/Pnas.1600374113  1
2016 Moorjani P, Sankararaman S, Fu Q, Przeworski M, Patterson N, Reich D. A genetic method for dating ancient genomes provides a direct estimate of human generation interval in the last 45,000 years. Proceedings of the National Academy of Sciences of the United States of America. PMID 27140627 DOI: 10.1073/Pnas.1514696113  1
2016 Gao Z, Wyman MJ, Sella G, Przeworski M. Interpreting the Dependence of Mutation Rates on Age and Time. Plos Biology. 14: e1002355. PMID 26761240 DOI: 10.1371/Journal.Pbio.1002355  1
2015 Morton ER, Lynch J, Froment A, Lafosse S, Heyer E, Przeworski M, Blekhman R, Ségurel L. Variation in Rural African Gut Microbiota Is Strongly Correlated with Colonization by Entamoeba and Subsistence. Plos Genetics. 11: e1005658. PMID 26619199 DOI: 10.1371/Journal.Pgen.1005658  1
2015 Singhal S, Leffler EM, Sannareddy K, Turner I, Venn O, Hooper DM, Strand AI, Li Q, Raney B, Balakrishnan CN, Griffith SC, McVean G, Przeworski M. Stable recombination hotspots in birds. Science (New York, N.Y.). 350: 928-32. PMID 26586757 DOI: 10.1126/Science.Aad0843  1
2015 Meyer WK, Venkat A, Kermany AR, van de Geijn B, Zhang S, Przeworski M. Evolutionary history inferred from the de novo assembly of a nonmodel organism, the blue-eyed black lemur. Molecular Ecology. 24: 4392-405. PMID 26198179 DOI: 10.1111/Mec.13327  1
2015 Williams AL, Genovese G, Dyer T, Altemose N, Truax K, Jun G, Patterson N, Myers SR, Curran JE, Duggirala R, Blangero J, Reich D, Przeworski M. Non-crossover gene conversions show strong GC bias and unexpected clustering in humans. Elife. 4. PMID 25806687 DOI: 10.7554/Elife.04637  1
2015 Gao Z, Waggoner D, Stephens M, Ober C, Przeworski M. An estimate of the average number of recessive lethal mutations carried by humans. Genetics. 199: 1243-54. PMID 25697177 DOI: 10.1534/Genetics.114.173351  1
2015 Gao Z, Przeworski M, Sella G. Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species. Evolution; International Journal of Organic Evolution. 69: 431-46. PMID 25403856 DOI: 10.1111/Evo.12567  1
2015 Williams AL, Genovese G, Dyer T, Altemose N, Truax K, Jun G, Patterson N, Myers SR, Curran JE, Duggirala R, Blangero J, Reich D, Przeworski M. Author response: Non-crossover gene conversions show strong GC bias and unexpected clustering in humans Elife. DOI: 10.7554/Elife.04637.012  1
2014 Ségurel L, Wyman MJ, Przeworski M. Determinants of mutation rate variation in the human germline. Annual Review of Genomics and Human Genetics. 15: 47-70. PMID 25000986 DOI: 10.1146/Annurev-Genom-031714-125740  1
2014 Kermany AR, Segurel L, Oliver TR, Przeworski M. TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception. Bioinformatics (Oxford, England). 30: 2035-42. PMID 24659032 DOI: 10.1093/Bioinformatics/Btu159  1
2013 Quach H, Wilson D, Laval G, Patin E, Manry J, Guibert J, Barreiro LB, Nerrienet E, Verschoor E, Gessain A, Przeworski M, Quintana-Murci L. Different selective pressures shape the evolution of Toll-like receptors in human and African great ape populations. Human Molecular Genetics. 22: 4829-40. PMID 23851028 DOI: 10.1093/Hmg/Ddt335  1
2013 Ségurel L, Gao Z, Przeworski M. Ancestry runs deeper than blood: the evolutionary history of ABO points to cryptic variation of functional importance. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 862-7. PMID 23836453 DOI: 10.1002/Bies.201300030  1
2013 Meyer WK, Zhang S, Hayakawa S, Imai H, Przeworski M. The convergent evolution of blue iris pigmentation in primates took distinct molecular paths. American Journal of Physical Anthropology. 151: 398-407. PMID 23640739 DOI: 10.1002/Ajpa.22280  1
2013 Leffler EM, Gao Z, Pfeifer S, Ségurel L, Auton A, Venn O, Bowden R, Bontrop R, Wall JD, Sella G, Donnelly P, McVean G, Przeworski M. Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science (New York, N.Y.). 339: 1578-82. PMID 23413192 DOI: 10.1126/Science.1234070  1
2012 Ségurel L, Thompson EE, Flutre T, Lovstad J, Venkat A, Margulis SW, Moyse J, Ross S, Gamble K, Sella G, Ober C, Przeworski M. The ABO blood group is a trans-species polymorphism in primates. Proceedings of the National Academy of Sciences of the United States of America. 109: 18493-8. PMID 23091028 DOI: 10.1073/Pnas.1210603109  1
2012 Leffler EM, Bullaughey K, Matute DR, Meyer WK, Ségurel L, Venkat A, Andolfatto P, Przeworski M. Revisiting an old riddle: what determines genetic diversity levels within species? Plos Biology. 10: e1001388. PMID 22984349 DOI: 10.1371/Journal.Pbio.1001388  1
2012 Auton A, Fledel-Alon A, Pfeifer S, Venn O, Ségurel L, Street T, Leffler EM, Bowden R, Aneas I, Broxholme J, Humburg P, Iqbal Z, Lunter G, Maller J, Hernandez RD, ... ... Przeworski M, et al. A fine-scale chimpanzee genetic map from population sequencing. Science (New York, N.Y.). 336: 193-8. PMID 22422862 DOI: 10.1126/Science.1216872  1
2012 Meyer WK, Arbeithuber B, Ober C, Ebner T, Tiemann-Boege I, Hudson RR, Przeworski M. Evaluating the evidence for transmission distortion in human pedigrees. Genetics. 191: 215-32. PMID 22377632 DOI: 10.1534/Genetics.112.139576  1
2011 Ségurel L, Leffler EM, Przeworski M. The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans. Plos Biology. 9: e1001211. PMID 22162947 DOI: 10.1371/Journal.Pbio.1001211  1
2011 Wilson DJ, Hernandez RD, Andolfatto P, Przeworski M. A population genetics-phylogenetics approach to inferring natural selection in coding sequences. Plos Genetics. 7: e1002395. PMID 22144911 DOI: 10.1371/Journal.Pgen.1002395  1
2011 Fledel-Alon A, Leffler EM, Guan Y, Stephens M, Coop G, Przeworski M. Variation in human recombination rates and its genetic determinants. Plos One. 6: e20321. PMID 21698098 DOI: 10.1371/Journal.Pone.0020321  1
2011 Hernandez RD, Kelley JL, Elyashiv E, Melton SC, Auton A, McVean G, Sella G, Przeworski M. Classic selective sweeps were rare in recent human evolution. Science (New York, N.Y.). 331: 920-4. PMID 21330547 DOI: 10.1126/Science.1198878  1
2011 Przeworski M. Genome-sequencing anniversary. The golden age of human population genetics. Science (New York, N.Y.). 331: 547. PMID 21292966 DOI: 10.1126/Science.1202571  0.01
2010 Elyashiv E, Bullaughey K, Sattath S, Rinott Y, Przeworski M, Sella G. Shifts in the intensity of purifying selection: an analysis of genome-wide polymorphism data from two closely related yeast species. Genome Research. 20: 1558-73. PMID 20817943 DOI: 10.1101/Gr.108993.110  1
2010 Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, Coop G, de Massy B. PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice. Science (New York, N.Y.). 327: 836-40. PMID 20044539 DOI: 10.1126/Science.1183439  1
2009 Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G, Przeworski M. Broad-scale recombination patterns underlying proper disjunction in humans. Plos Genetics. 5: e1000658. PMID 19763175 DOI: 10.1371/Journal.Pgen.1000658  1
2009 Sella G, Petrov DA, Przeworski M, Andolfatto P. Pervasive natural selection in the Drosophila genome? Plos Genetics. 5: e1000495. PMID 19503600 DOI: 10.1371/Journal.Pgen.1000495  1
2009 Becquet C, Przeworski M. Learning about modes of speciation by computational approaches. Evolution; International Journal of Organic Evolution. 63: 2547-62. PMID 19228187 DOI: 10.1111/J.1558-5646.2009.00662.X  1
2008 Blekhman R, Man O, Herrmann L, Boyko AR, Indap A, Kosiol C, Bustamante CD, Teshima KM, Przeworski M. Natural selection on genes that underlie human disease susceptibility. Current Biology : Cb. 18: 883-9. PMID 18571414 DOI: 10.1016/J.Cub.2008.04.074  1
2008 Coop G, Bullaughey K, Luca F, Przeworski M. The timing of selection at the human FOXP2 gene. Molecular Biology and Evolution. 25: 1257-9. PMID 18413354 DOI: 10.1093/Molbev/Msn091  1
2008 Coop G, Wen X, Ober C, Pritchard JK, Przeworski M. High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science (New York, N.Y.). 319: 1395-8. PMID 18239090 DOI: 10.1126/Science.1151851  1
2008 Bullaughey K, Przeworski M, Coop G. No effect of recombination on the efficacy of natural selection in primates. Genome Research. 18: 544-54. PMID 18199888 DOI: 10.1101/Gr.071548.107  1
2007 Becquet C, Przeworski M. A new approach to estimate parameters of speciation models with application to apes. Genome Research. 17: 1505-19. PMID 17712021 DOI: 10.1101/Gr.6409707  1
2007 Becquet C, Patterson N, Stone AC, Przeworski M, Reich D. Genetic structure of chimpanzee populations. Plos Genetics. 3: e66. PMID 17447846 DOI: 10.1371/Journal.Pgen.0030066  1
2007 Clark VJ, Ptak SE, Tiemann I, Qian Y, Coop G, Stone AC, Przeworski M, Arnheim N, Di Rienzo A. Combining sperm typing and linkage disequilibrium analyses reveals differences in selective pressures or recombination rates across human populations. Genetics. 175: 795-804. PMID 17151245 DOI: 10.1534/Genetics.106.064964  1
2007 Coop G, Przeworski M. An evolutionary view of human recombination. Nature Reviews. Genetics. 8: 23-34. PMID 17146469 DOI: 10.1038/Nrg1947  1
2006 Teshima KM, Coop G, Przeworski M. How reliable are empirical genomic scans for selective sweeps? Genome Research. 16: 702-12. PMID 16687733 DOI: 10.1101/Gr.5105206  1
2006 Teshima KM, Przeworski M. Directional positive selection on an allele of arbitrary dominance. Genetics. 172: 713-8. PMID 16219788 DOI: 10.1534/Genetics.105.044065  1
2005 Przeworski M, Coop G, Wall JD. The signature of positive selection on standing genetic variation. Evolution; International Journal of Organic Evolution. 59: 2312-23. PMID 16396172 DOI: 10.1111/J.0014-3820.2005.Tb00941.X  1
2005 Przeworski M. Genetics. Motivating hotspots. Science (New York, N.Y.). 310: 247-8. PMID 16224010 DOI: 10.1126/Science.1120154  0.01
2005 Römpler H, Schulz A, Pitra C, Coop G, Przeworski M, Pääbo S, Schöneberg T. The rise and fall of the chemoattractant receptor GPR33. The Journal of Biological Chemistry. 280: 31068-75. PMID 15987686 DOI: 10.1074/Jbc.M503586200  1
2005 Ptak SE, Hinds DA, Koehler K, Nickel B, Patil N, Ballinger DG, Przeworski M, Frazer KA, Pääbo S. Fine-scale recombination patterns differ between chimpanzees and humans. Nature Genetics. 37: 429-34. PMID 15723063 DOI: 10.1038/Ng1529  1
2004 Ptak SE, Roeder AD, Stephens M, Gilad Y, Pääbo S, Przeworski M. Absence of the TAP2 human recombination hotspot in chimpanzees. Plos Biology. 2: e155. PMID 15208713 DOI: 10.1371/Journal.Pbio.0020155  1
2004 Ptak SE, Voelpel K, Przeworski M. Insights into recombination from patterns of linkage disequilibrium in humans. Genetics. 167: 387-97. PMID 15166163 DOI: 10.1534/Genetics.167.1.387  1
2004 Fischer A, Wiebe V, Pääbo S, Przeworski M. Evidence for a complex demographic history of chimpanzees. Molecular Biology and Evolution. 21: 799-808. PMID 14963091 DOI: 10.1093/Molbev/Msh083  1
2004 Gilad Y, Wiebe V, Przeworski M, Lancet D, Pääbo S. Loss of olfactory receptor genes coincides with the acquisition of full trichromatic vision in primates. Plos Biology. 2: E5. PMID 14737185 DOI: 10.1371/Journal.Pbio.0020005  1
2003 Przeworski M. Estimating the time since the fixation of a beneficial allele. Genetics. 164: 1667-76. PMID 12930770  0.01
2003 Hellmann I, Ebersberger I, Ptak SE, Pääbo S, Przeworski M. A neutral explanation for the correlation of diversity with recombination rates in humans. American Journal of Human Genetics. 72: 1527-35. PMID 12740762 DOI: 10.1086/375657  1
2002 Ptak SE, Przeworski M. Evidence for population growth in humans is confounded by fine-scale population structure. Trends in Genetics : Tig. 18: 559-63. PMID 12414185 DOI: 10.1016/S0168-9525(02)02781-6  1
2002 Wall JD, Andolfatto P, Przeworski M. Testing models of selection and demography in Drosophila simulans. Genetics. 162: 203-16. PMID 12242234  1
2002 Enard W, Przeworski M, Fisher SE, Lai CS, Wiebe V, Kitano T, Monaco AP, Pääbo S. Molecular evolution of FOXP2, a gene involved in speech and language. Nature. 418: 869-72. PMID 12192408 DOI: 10.1038/Nature01025  1
2002 Przeworski M. The signature of positive selection at randomly chosen loci. Genetics. 160: 1179-89. PMID 11901132  0.01
2002 Gilad Y, Rosenberg S, Przeworski M, Lancet D, Skorecki K. Evidence for positive selection and population structure at the human MAO-A gene. Proceedings of the National Academy of Sciences of the United States of America. 99: 862-7. PMID 11805333 DOI: 10.1073/Pnas.022614799  1
2001 Pritchard JK, Przeworski M. Linkage disequilibrium in humans: models and data. American Journal of Human Genetics. 69: 1-14. PMID 11410837 DOI: 10.1086/321275  1
2001 Andolfatto P, Przeworski M. Regions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster. Genetics. 158: 657-65. PMID 11404330  1
2001 Przeworski M, Wall JD. Why is there so little intragenic linkage disequilibrium in humans? Genetical Research. 77: 143-51. PMID 11355570 DOI: 10.1017/S0016672301004967  1
2001 Przeworski M, Wall JD, Andolfatto P. Recombination and the frequency spectrum in Drosophila melanogaster and Drosophila simulans. Molecular Biology and Evolution. 18: 291-8. PMID 11230530 DOI: 10.1093/Oxfordjournals.Molbev.A003805  1
2000 Andolfatto P, Przeworski M. A genome-wide departure from the standard neutral model in natural populations of Drosophila. Genetics. 156: 257-68. PMID 10978290  1
2000 Wall JD, Przeworski M. When did the human population size start increasing? Genetics. 155: 1865-74. PMID 10924481  1
2000 Przeworski M, Hudson RR, Di Rienzo A. Adjusting the focus on human variation. Trends in Genetics : Tig. 16: 296-302. PMID 10858659 DOI: 10.1016/S0168-9525(00)02030-8  1
1999 Przeworski M, Charlesworth B, Wall JD. Genealogies and weak purifying selection. Molecular Biology and Evolution. 16: 246-52. PMID 10084898 DOI: 10.1093/Oxfordjournals.Molbev.A026106  1
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