Deborah A. O'Brien - Publications

Affiliations: 
Cell & Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cell Biology, Evolution and Development Biology, Genetics

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Danshina PV, Qu W, Temple BR, Rojas RJ, Miley MJ, Machius M, Betts L, O'Brien DA. Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme. Molecular Human Reproduction. PMID 26921398 DOI: 10.1093/molehr/gaw016  0.6
2015 Odet F, Pan W, Bell TA, Goodson SG, Stevans AM, Yun Z, Aylor DL, Kao CY, McMillan L, Pardo-Manuel de Villena F, O'Brien DA. The Founder Strains of the Collaborative Cross Express a Complex Combination of Advantageous and Deleterious Traits for Male Reproduction. G3 (Bethesda, Md.). PMID 26483008 DOI: 10.1534/g3.115.020172  0.6
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/journal.pgen.1004850  0.6
2012 Goodson SG, Qiu Y, Sutton KA, Xie G, Jia W, O'Brien DA. Metabolic substrates exhibit differential effects on functional parameters of mouse sperm capacitation. Biology of Reproduction. 87: 75. PMID 22837480 DOI: 10.1095/biolreprod.112.102673  0.6
2012 Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/genetics.111.132639  0.6
2011 Sexton JZ, Danshina PV, Lamson DR, Hughes M, House AJ, Yeh LA, O'Brien DA, Williams KP. Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS). Current Chemical Genomics. 5: 30-41. PMID 21760877 DOI: 10.2174/1875397301105010030  0.6
2011 Goodson SG, Zhang Z, Tsuruta JK, Wang W, O'Brien DA. Classification of mouse sperm motility patterns using an automated multiclass support vector machines model. Biology of Reproduction. 84: 1207-15. PMID 21349820 DOI: 10.1095/biolreprod.110.088989  0.6
2011 Lamson DR, House AJ, Danshina PV, Sexton JZ, Sanyang K, O'Brien DA, Yeh LA, Williams KP. Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells. Protein Expression and Purification. 75: 104-13. PMID 20828617 DOI: 10.1016/j.pep.2010.09.003  0.6
2010 Goto M, O'Brien DA, Eddy EM. Speriolin is a novel human and mouse sperm centrosome protein. Human Reproduction (Oxford, England). 25: 1884-94. PMID 20542897 DOI: 10.1093/humrep/deq138  0.6
2010 Vemuganti SA, de Villena FP, O'Brien DA. Frequent and recent retrotransposition of orthologous genes plays a role in the evolution of sperm glycolytic enzymes. Bmc Genomics. 11: 285. PMID 20459611 DOI: 10.1186/1471-2164-11-285  0.6
2010 Danshina PV, Geyer CB, Dai Q, Goulding EH, Willis WD, Kitto GB, McCarrey JR, Eddy EM, O'Brien DA. Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice. Biology of Reproduction. 82: 136-45. PMID 19759366 DOI: 10.1095/biolreprod.109.079699  0.6
2009 Hu Y, Yu H, Pask AJ, O'Brien DA, Shaw G, Renfree MB. A-kinase anchoring protein 4 has a conserved role in mammalian spermatogenesis. Reproduction (Cambridge, England). 137: 645-53. PMID 19139142 DOI: 10.1530/REP-08-0337  0.6
2008 Kaneto M, Krisfalusi M, Eddy EM, O'Brien DA, Miki K. Bicarbonate-induced phosphorylation of p270 protein in mouse sperm by cAMP-dependent protein kinase. Molecular Reproduction and Development. 75: 1045-53. PMID 18357561 DOI: 10.1002/mrd.20839  0.6
2008 Sawyer GM, Monzingo AF, Poteet EC, O'Brien DA, Robertus JD. X-ray analysis of phosphoglycerate kinase 2, a sperm-specific isoform from Mus musculus. Proteins. 71: 1134-44. PMID 18004764 DOI: 10.1002/prot.21801  0.6
2008 Nakamura N, Shibata H, O'Brien DA, Mori C, Eddy EM. Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. Molecular Reproduction and Development. 75: 632-40. PMID 17924400 DOI: 10.1002/mrd.20791  0.6
2007 Vemuganti SA, Bell TA, Scarlett CO, Parker CE, de Villena FP, O'Brien DA. Three male germline-specific aldolase A isozymes are generated by alternative splicing and retrotransposition. Developmental Biology. 309: 18-31. PMID 17659271 DOI: 10.1016/j.ydbio.2007.06.010  0.6
2007 Buchold GM, Magyar PL, O'Brien DA. Mice lacking cyclin-dependent kinase inhibitor p19Ink4d show strain-specific effects on male reproduction. Molecular Reproduction and Development. 74: 1008-20. PMID 17393423 DOI: 10.1002/mrd.20715  0.6
2007 Buchold GM, Magyar PL, Arumugam R, Lee MM, O'Brien DA. p19Ink4d and p18Ink4c cyclin-dependent kinase inhibitors in the male reproductive axis. Molecular Reproduction and Development. 74: 997-1007. PMID 17342741 DOI: 10.1002/mrd.20716  0.6
2006 Yuan W, Leisner TM, McFadden AW, Clark S, Hiller S, Maeda N, O'Brien DA, Parise LV. CIB1 is essential for mouse spermatogenesis. Molecular and Cellular Biology. 26: 8507-14. PMID 16982698 DOI: 10.1128/MCB.01488-06  0.6
2006 Welch JE, Barbee RR, Magyar PL, Bunch DO, O'Brien DA. Expression of the spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase (GAPDS) in rat testis. Molecular Reproduction and Development. 73: 1052-60. PMID 16700075 DOI: 10.1002/mrd.20235  0.6
2006 Krisfalusi M, Miki K, Magyar PL, O'Brien DA. Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa. Biology of Reproduction. 75: 270-8. PMID 16687649 DOI: 10.1095/biolreprod.105.049684  0.6
2005 Holsberger DR, Buchold GM, Leal MC, Kiesewetter SE, O'Brien DA, Hess RA, França LR, Kiyokawa H, Cooke PS. Cell-cycle inhibitors p27Kip1 and p21Cip1 regulate murine Sertoli cell proliferation. Biology of Reproduction. 72: 1429-36. PMID 15728790 DOI: 10.1095/biolreprod.105.040386  0.6
2004 Miki K, Qu W, Goulding EH, Willis WD, Bunch DO, Strader LF, Perreault SD, Eddy EM, O'Brien DA. Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proceedings of the National Academy of Sciences of the United States of America. 101: 16501-6. PMID 15546993 DOI: 10.1073/pnas.0407708101  0.6
2003 Eddy EM, Toshimori K, O'Brien DA. Fibrous sheath of mammalian spermatozoa. Microscopy Research and Technique. 61: 103-15. PMID 12672126 DOI: 10.1002/jemt.10320  0.6
2003 Yang G, Zhang YL, Buchold GM, Jetten AM, O'Brien DA. Analysis of germ cell nuclear factor transcripts and protein expression during spermatogenesis. Biology of Reproduction. 68: 1620-30. PMID 12606326 DOI: 10.1095/biolreprod.102.012013  0.6
2003 Yang J, Chennathukuzhi V, Miki K, O'Brien DA, Hecht NB. Mouse testis brain RNA-binding protein/translin selectively binds to the messenger RNA of the fibrous sheath protein glyceraldehyde 3-phosphate dehydrogenase-S and suppresses its translation in vitro. Biology of Reproduction. 68: 853-9. PMID 12604635 DOI: 10.1095/biolreprod.102.008631  0.6
2002 Akama TO, Nakagawa H, Sugihara K, Narisawa S, Ohyama C, Nishimura S, O'Brien DA, Moremen KW, Millan JL, Fukuda MN. Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science (New York, N.Y.). 295: 124-7. PMID 11778047 DOI: 10.1126/science.1065570  0.6
2001 Yang G, Gregory CW, Shang Q, O'Brien DA, Zhang YL. Differential expression of CCAAT/enhancer-binding protein-δ (C/EBPδ) in rat androgen-dependent tissues and human prostate cancer Journal of Andrology. 22: 471-480. PMID 11330648  0.6
2000 Tsuruta JK, Eddy EM, O'Brien DA. Insulin-like growth factor-II/cation-independent mannose 6-phosphate receptor mediates paracrine interactions during spermatogonial development Biology of Reproduction. 63: 1006-1013. PMID 10993821  0.6
2000 Franklin DS, Godfrey VL, O'Brien DA, Deng C, Xiong Y. Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity Molecular and Cellular Biology. 20: 6147-6158. PMID 10913196 DOI: 10.1128/MCB.20.16.6147-6158.2000  0.6
2000 Welch JE, Brown PL, O'Brien DA, Magyar PL, Bunch DO, Mori C, Eddy EM. Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells Journal of Andrology. 21: 328-338. PMID 10714828  0.6
2000 Pace AJ, Lee E, Athirakul K, Coffman TM, O'Brien DA, Koller BH. Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter. The Journal of Clinical Investigation. 105: 441-50. PMID 10683373 DOI: 10.1172/JCI8553  0.6
1999 McCarrey JR, O'Brien DA, Skinner MK. Construction and preliminary characterization of a series of mouse and rat testis cDNA libraries Journal of Andrology. 20: 635-639. PMID 10520576  0.6
1998 Zhang YL, Akmal KM, Tsuruta JK, Shang Q, Hirose T, Jetten AM, Kim KH, O'Brien DA. Expression of germ cell nuclear factor (GCNF/RTR) during spermatogenesis Molecular Reproduction and Development. 50: 93-102. PMID 9547515 DOI: 10.1002/(SICI)1098-2795(199805)50:1<93::AID-MRD12>3.0.CO;2-Z  0.6
1998 Bunch DO, Welch JE, Magyar PL, Eddy EM, O'Brien DA. Glyceraldehyde 3-phosphate dehydrogenase-S protein distribution during mouse spermatogenesis Biology of Reproduction. 58: 834-841. PMID 9510974 DOI: 10.1095/biolreprod58.3.834  0.6
1998 Hagaman JR, Moyer JS, Bachman ES, Sibony M, Magyar PL, Welch JE, Smithies O, Krege JH, O'Brien DA. Angiotensin-converting enzyme and male fertility. Proceedings of the National Academy of Sciences of the United States of America. 95: 2552-7. PMID 9482924 DOI: 10.1073/pnas.95.5.2552  0.6
1998 Eddy EM, O'Brien DA. Gene expression during mammalian meiosis Current Topics in Developmental Biology. 37: 141-200. PMID 9352186  0.6
1997 Joseph DR, O'Brien DA, Sullivan PM, Becchis M, Tsuruta JK, Petrusz P. Overexpression of androgen-binding protein/sex hormone-binding globulin in male transgenic mice: Tissue distribution and phenotypic disorders Biology of Reproduction. 56: 21-32. PMID 9002629 DOI: 10.1095/biolreprod56.1.21  0.6
1996 O'Brien DA, Welch JE, Goulding EH, Taylor AA, Baba T, Hecht NB, Eddy EM. Boar proacrosin expressed in spermatids of transgenic mice does not reach the acrosome and disrupts spermatogenesis. Molecular Reproduction and Development. 43: 236-47. PMID 8824922 DOI: 10.1002/(SICI)1098-2795(199602)43:2<236::AID-MRD13>3.0.CO;2-1  0.6
1995 Fulcher KD, Welch JE, Klapper DG, O'Brien DA, Eddy EM. Identification of a unique μ-class glutathione S-transferase in mouse spermatogenic cells Molecular Reproduction and Development. 42: 415-424. PMID 8607970 DOI: 10.1002/mrd.1080420407  0.6
1995 Tsuruta JK, O'Brien DA. Sertoli cell-spermatogenic cell interaction: The insulin-like growth factor-II/cation-independent mannose 6-phosphate receptor mediates changes in spermatogenic cell gene expression in mice Biology of Reproduction. 53: 1454-1464. PMID 8562703 DOI: 10.1095/biolreprod53.6.1454  0.6
1995 Hirose T, O'Brien DA, Jetten AM. RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis Gene. 152: 247-251. PMID 7835709 DOI: 10.1016/0378-1119(94)00656-D  0.6
1995 Welch JE, Brown PR, O'Brien DA, Eddy EM. Genomic organization of a mouse glyceraldehyde 3-phosphate dehydrogenase gene (Gapd-s) expressed in post-meiotic spermatogenic cells Developmental Genetics. 16: 179-189. PMID 7736666 DOI: 10.1002/dvg.1020160210  0.6
1995 Fulcher KD, Mori C, Welch JE, O'Brien DA, Klapper DG, Eddy EM. Characterization of Fsc1 cDNA for a mouse sperm fibrous sheath component Biology of Reproduction. 52: 41-49. PMID 7711182 DOI: 10.1095/biolreprod52.1.41  0.6
1995 Hirose T, O'Brien DA, Jetten AM. Cloning of the gene encoding the murine orphan receptor TAK1 and cell-type-specific expression in testis Gene. 163: 239-242. PMID 7590273 DOI: 10.1016/0378-1119(95)00414-2  0.6
1995 Raburn DJ, Hamil KG, Tsuruta JK, O'Brien DA, Hall SH. Stage-specific expression of B cell translocation gene 1 in rat testis Endocrinology. 136: 5769-5777. PMID 7588335  0.6
1994 O'Brien DA, Welch JE, Fulcher KD, Eddy EM. Expression of mannose 6-phosphate receptor messenger ribonucleic acids in mouse spermatogenic and Sertoli cells Biology of Reproduction. 50: 429-435. PMID 8142560  0.6
1993 Fulcher KD, Welch JE, Davis CM, O'Brien DA, Eddy EM. Characterization of laminin receptor messenger ribonucleic acid and protein expression in mouse spermatogenic cells Biology of Reproduction. 48: 674-682. PMID 8452943 DOI: 10.1095/biolreprod48.3.674  0.6
1993 Mori C, Welch JE, Fulcher KD, O'Brien DA, Eddy EM. Unique hexokinase messenger ribonucleic acids lacking the porin-binding domain are developmentally expressed in mouse spermatogenic cells Biology of Reproduction. 49: 191-203. PMID 8396993  0.6
1993 O'Brien DA, Gabel CA, Eddy EM. Mouse Sertoli cells secrete mannose 6-phosphate containing glycoproteins that are endocytosed by spermatogenic cells Biology of Reproduction. 49: 1055-1065. PMID 8286571 DOI: 10.1095/biolreprod49.5.1055  0.6
1993 Tsuruta JK, O'Brien DA, Griswold MD. Sertoli cell and germ cell cystatin C: Stage-dependent expression of two distinct messenger ribonucleic acid transcripts in rat testes Biology of Reproduction. 49: 1045-1054. PMID 8286570 DOI: 10.1095/biolreprod49.5.1045  0.6
1993 MacCalman CD, O'Brien DA, Byers S, Blaschuk OW. N-cadherin expression in the seminiferous epithelium of the mouse testis Endocrine. 1: 519-525.  0.6
1992 Rosario MO, Perkins SL, O'Brien DA, Allen RL, Eddy EM. Identification of the gene for the developmentally expressed 70 kDa heat-shock protein (P70) of mouse spermatogenic cells. Developmental Biology. 150: 1-11. PMID 1537426 DOI: 10.1016/0012-1606(92)90002-X  0.6
1992 Welch JE, Schatte EC, O'Brien DA, Eddy EM. Expression of a glyceraldehyde 3-phosphate dehydrogenase gene specific to mouse spermatogenic cells Biology of Reproduction. 46: 869-878. PMID 1375514  0.6
1992 Welch JE, Swinnen JV, O'Brien DA, Eddy EM, Conti M. Unique adenosine 3',5' cyclic monophosphate phosphodiesterase messenger ribonucleic acids in rat spermatogenic cells: Evidence for differential gene expression during spermatogenesis Biology of Reproduction. 46: 1027-1033. PMID 1327199 DOI: 10.1095/biolreprod46.6.1027  0.6
1991 Eddy EM, McGee RS, Willis WD, O'Brien DA. Immunodissection of sperm surface modifications during epididymal maturation. Bulletin De L'Association Des Anatomistes. 75: 139-44. PMID 1782451  0.6
1991 Eddy EM, O'Brien DA, Fenderson BA, Welch JE. Intermediate filament-like proteins in the fibrous sheath of the mouse sperm flagellum Annals of the New York Academy of Sciences. 637: 224-239. PMID 1723852  0.6
1991 O'Brien DA, Gabel CA, Welch JE, Eddy EM. Mannose 6-phosphate receptors: Potential mediators of germ cell-Sertoli cell interactions Annals of the New York Academy of Sciences. 637: 327-339. PMID 1664679  0.6
1989 Li SSL, O'Brien DA, Hou EW, Versola J, Rockett DL, Eddy EM. Differential activity and synthesis of lactate dehydrogenase isozymes A (muscle), B (heart), and C (testis) in mouse spermatogenic cells Biology of Reproduction. 40: 173-180. PMID 2923949  0.6
1989 Maekawa M, O'Brien DA, Allen RL, Eddy EM. Heat-shock cognate protein (hsc71) and related proteins in mouse spermatogenic cells. Biology of Reproduction. 40: 843-52. PMID 2665832  0.6
1989 O'Brien DA, Gabel CA, Rockett DL, Eddy EM. Receptor-mediated endocytosis and differential synthesis of mannose 6-phosphate receptors in isolated spermatogenic and Sertoli cells Endocrinology. 125: 2973-2984. PMID 2555133  0.6
1988 O'Brien DA, Gerton GL, Eddy EM. Acrosomal constituents identified with a monoclonal antibody are modified during late spermiogenesis in the mouse Biology of Reproduction. 38: 955-967. PMID 3401549  0.6
1988 Allen RL, O'Brien DA, Eddy EM. A novel hsp70-like protein (P70) is present in mouse spermatogenic cells. Molecular and Cellular Biology. 8: 828-32. PMID 3352605  0.6
1988 Allen RL, O'Brien DA, Jones CC, Rockett DL, Eddy EM. Expression of heat shock proteins by isolated mouse spermatogenic cells. Molecular and Cellular Biology. 8: 3260-6. PMID 3211143  0.6
1988 Gerton GL, O'Brien DA, Eddy EM. Antigens recognized by monoclonal antibody to mouse acrosomal components differ in guinea pig spermatogenic cells and sperm Biology of Reproduction. 39: 431-441. PMID 3052603  0.6
1987 O'Brien DA. Stage-specific protein synthesis by isolated spermatogenic cells throughout meiosis and early spermiogenesis in the mouse Biology of Reproduction. 37: 147-157. PMID 3651542  0.6
1987 O'Brien DA, Froysa A, Rockett DL, Hansson V, Eddy EM. Retinoids decrease viability and ATP levels of round spermatids in vitro Annals of the New York Academy of Sciences. 513: 477-479. DOI: 10.1111/j.1749-6632.1987.tb25077.x  0.6
1986 O'Brien DA, Millette CF. Immunochemical identification of multiple cell surface antigens appearing during specific stages of mouse spermatogenesis Gamete Research. 13: 199-211.  0.6
1984 Venolia L, Cooper DW, O'Brien DA, Millette CF, Gartler SM. Transformation of the Hprt gene with DNA from spermatogenic cells - Implications for the evolution of X chromosome inactivation Chromosoma. 90: 185-189. PMID 6541992 DOI: 10.1007/BF00292395  0.6
1984 Fenderson BA, O'Brien DA, Millette CF, Eddy EM. Stage-specific expression of three cell surface carbohydrate antigens during murine spermatogenesis detected with monoclonal antibodies Developmental Biology. 103: 117-128. PMID 6370756 DOI: 10.1016/0012-1606(84)90013-7  0.6
1984 O'Brien DA, Millette CF. Identification and immunochemical characterization of spermatogenic cell surface antigens that appear during early meiotic prophase Developmental Biology. 101: 307-317. PMID 6363162 DOI: 10.1016/0012-1606(84)90144-1  0.6
1980 Millette CF, O'Brien DA, Moulding CT. Isolation of plasma membranes from purified mouse spermatogenic cells Journal of Cell Science. 279-299. PMID 7419622  0.6
1980 O'Brien DA, Bellvé AR. Protein constituents of the mouse spermatozoon. II. Temporal synthesis during spermatogenesis Developmental Biology. 75: 405-418. PMID 7372006 DOI: 10.1016/0012-1606(80)90172-4  0.6
1980 O'Brien DA, Bellvé AR. Protein constituents of the mouse spermatozoon. I. An electrophoretic characterization Developmental Biology. 75: 386-404. PMID 7372005 DOI: 10.1016/0012-1606(80)90171-2  0.6
1977 Bellve AR, Millette CF, Bhatnagar YM, O'Brien DA. Dissociation of the mouse testis and characterization of isolated spermatogenic cells Journal of Histochemistry and Cytochemistry. 25: 480-494. PMID 893996  0.6
1977 Bellve AR, Cavicchia JC, Millette CF, O'Brien DA, Bhatnagar YM, Dym M. Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization Journal of Cell Biology. 74: 68-85. PMID 874003  0.6
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