Sara L. Sawyer, Ph.D. - Publications

Molecular Genetics & Microbiology University of Texas at Austin, Austin, Texas, U.S.A. 
host-virus interactions, DNA repair

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Stanley JT, Gilchrist AR, Stabell AC, Allen MA, Sawyer SL, Dowell RD. Two-stage ML Classifier for Identifying Host Protein Targets of the Dengue Protease. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 25: 487-498. PMID 31797621  0.64
2019 Decker CJ, Steiner HR, Hoon-Hanks LL, Morrison JH, Haist KC, Stabell AC, Poeschla EM, Morrison TE, Stenglein MD, Sawyer SL, Parker R. dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA. Viruses. 11. PMID 31615058 DOI: 10.3390/v11100943  0.64
2019 Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Méndez-Solís O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, ... ... Sawyer SL, et al. TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Reports. 27: 3269-3283.e6. PMID 31189110 DOI: 10.1016/j.celrep.2019.05.040  0.8
2019 Warren CJ, Meyerson NR, Dirasantha O, Feldman ER, Wilkerson GK, Sawyer SL. Selective use of primate CD4 receptors by HIV-1. Plos Biology. 17: e3000304. PMID 31181085 DOI: 10.1371/journal.pbio.3000304  0.8
2019 Warren CJ, Meyerson NR, Stabell AC, Fattor WT, Wilkerson GK, Sawyer SL. A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV). Proceedings of the National Academy of Sciences of the United States of America. PMID 31113887 DOI: 10.1073/pnas.1813909116  0.8
2019 Hawkins JA, Kaczmarek ME, Müller MA, Drosten C, Press WH, Sawyer SL. A metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 species. Proceedings of the National Academy of Sciences of the United States of America. PMID 31113885 DOI: 10.1073/pnas.1814995116  0.48
2019 Warren CJ, Sawyer SL. How host genetics dictates successful viral zoonosis. Plos Biology. 17: e3000217. PMID 31002666 DOI: 10.1371/journal.pbio.3000217  0.72
2018 Rowley PA, Patterson K, Sandmeyer SB, Sawyer SL. Control of yeast retrotransposons mediated through nucleoporin evolution. Plos Genetics. 14: e1007325. PMID 29694349 DOI: 10.1371/journal.pgen.1007325  0.8
2018 Meyerson NR, Warren CJ, Vieira DASA, Diaz-Griffero F, Sawyer SL. Correction: Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes. Plos Pathogens. 14: e1006983. PMID 29614111 DOI: 10.1371/journal.ppat.1006983  0.8
2018 Stabell AC, Meyerson NR, Gullberg RC, Gilchrist AR, Webb KJ, Old WM, Perera R, Sawyer SL. Dengue viruses cleave STING in humans but not in nonhuman primates, their presumed natural reservoir. Elife. 7. PMID 29557779 DOI: 10.7554/eLife.31919  0.8
2018 Meyerson NR, Warren CJ, Vieira DASA, Diaz-Griferro F, Sawyer SL. Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes. Plos Pathogens. 14: e1006906. PMID 29518153 DOI: 10.1371/journal.ppat.1006906  0.8
2017 Meyerson NR, Zhou L, Guo YR, Zhao C, Tao YJ, Krug RM, Sawyer SL. Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation. Cell Host & Microbe. PMID 29107643 DOI: 10.1016/j.chom.2017.10.003  0.8
2017 Nahabedian J, Sharma A, Kaczmarek ME, Wilkerson GK, Sawyer SL, Overbaugh J. Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry. Virology. 512: 180-186. PMID 28972927 DOI: 10.1016/j.virol.2017.09.018  0.64
2016 Stabell AC, Hawkins J, Li M, Gao X, David M, Press WH, Sawyer SL. Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins. Plos Pathogens. 12: e1006066. PMID 28027315 DOI: 10.1371/journal.ppat.1006066  0.64
2016 Rowley PA, Ho B, Bushong S, Johnson A, Sawyer SL. XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts. Plos Pathogens. 12: e1005890. PMID 27711183 DOI: 10.1371/journal.ppat.1005890  0.8
2016 Lou DI, Kim ET, Meyerson NR, Pancholi NJ, Mohni KN, Enard D, Petrov DA, Weller SK, Weitzman MD, Sawyer SL. An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. Cell Host & Microbe. 20: 178-188. PMID 27512903 DOI: 10.1016/j.chom.2016.07.003  1
2016 White TE, Brandariz-Nuñez A, Han K, Sawyer SL, Kim B, Diaz-Griffero F. Modulation of LINE-1 Retrotransposition by a Human SAMHD1 Polymorphism. Virology Reports. 6: 53-60. PMID 27482511 DOI: 10.1016/j.virep.2016.06.001  1
2016 Nepveu-Traversy MÉ, Demogines A, Fricke T, Plourde MB, Riopel K, Veillette M, Diaz-Griffero F, Sawyer SL, Berthoux L. A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction. Heliyon. 2: e00056. PMID 27441239 DOI: 10.1016/j.heliyon.2015.e00056  0.36
2016 Wilke CO, Sawyer SL. At the mercy of viruses. Elife. 5. PMID 27187565 DOI: 10.7554/eLife.16758  1
2016 Nepveu-Traversy MÉ, Demogines A, Fricke T, Plourde MB, Riopel K, Veillette M, Diaz-Griffero F, Sawyer SL, Berthoux L. A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction Heliyon. 2. DOI: 10.1016/j.heliyon.2015.e00056  1
2015 Ng M, Ndungo E, Kaczmarek ME, Herbert AS, Binger T, Kuehne AI, Jangra RK, Hawkins JA, Gifford RJ, Biswas R, Demogines A, James RM, Yu M, Brummelkamp TR, Drosten C, ... ... Sawyer SL, et al. Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats. Elife. 4. PMID 26698106 DOI: 10.7554/eLife.11785  1
2015 Hussmann JA, Patchett S, Johnson A, Sawyer S, Press WH. Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast. Plos Genetics. 11: e1005732. PMID 26656907 DOI: 10.1371/journal.pgen.1005732  1
2015 Kerr SA, Jackson EL, Lungu OI, Meyer AG, Demogines A, Ellington AD, Georgiou G, Wilke CO, Sawyer SL. Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses. Journal of Virology. 89: 11643-53. PMID 26355089 DOI: 10.1128/JVI.01408-15  1
2015 Sawyer SL, Hartley T, Dyment DA, Beaulieu CL, Schwartzentruber J, Smith A, Bedford HM, Bernard G, Bernier FP, Brais B, Bulman DE, Chardon JW, Chitayat D, Deladoëy J, Fernandez BA, et al. Utility of whole-exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care. Clinical Genetics. PMID 26283276 DOI: 10.1111/cge.12654  0.32
2015 McDonell LM, Kernohan KD, Boycott KM, Sawyer SL. Receptor tyrosine kinase mutations in developmental syndromes and cancer: two sides of the same coin. Human Molecular Genetics. PMID 26152202 DOI: 10.1093/hmg/ddv254  0.32
2015 Sawyer SL, Cheuk-Him Ng A, Innes AM, Wagner JD, Dyment DA, Tetreault M, Majewski J, Boycott KM, Screaton RA, Nicholson G. Homozygous mutations in MFN2 cause multiple symmetric lipomatosis associated with neuropathy. Human Molecular Genetics. PMID 26085578 DOI: 10.1093/hmg/ddv229  0.32
2015 Meyerson NR, Sharma A, Wilkerson GK, Overbaugh J, Sawyer SL. Identification of Owl Monkey CD4 Receptors Broadly Compatible with Early-Stage HIV-1 Isolates. Journal of Virology. 89: 8611-22. PMID 26063421 DOI: 10.1128/JVI.00890-15  1
2015 Balci TB, Sawyer SL, Davila J, Humphreys P, Dyment DA. Brain malformations in a patient with deletion 2p16.1: A refinement of the phenotype to BCL11A. European Journal of Medical Genetics. 58: 351-4. PMID 25979662 DOI: 10.1016/j.ejmg.2015.04.006  0.32
2015 Liu H, Sawyer SL, Gos M, Grynspan D, Issa K, Ramphal R, Rotaru C, Consortium FC, Majewski J, Boycott KM, Graham G, Bromwich M. Atypical fibrodysplasia ossificans progressiva diagnosed by whole-exome sequencing. American Journal of Medical Genetics. Part A. 167: 1337-41. PMID 25899773 DOI: 10.1002/ajmg.a.36969  0.32
2015 McBee RM, Rozmiarek SA, Meyerson NR, Rowley PA, Sawyer SL. The effect of species representation on the detection of positive selection in primate gene data sets. Molecular Biology and Evolution. 32: 1091-6. PMID 25556235 DOI: 10.1093/molbev/msu399  1
2015 Sawyer SL, Tian L, Kähkönen M, Schwartzentruber J, Kircher M, Majewski J, Dyment DA, Innes AM, Boycott KM, Moreau LA, Moilanen JS, Greenberg RA. Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype. Cancer Discovery. 5: 135-42. PMID 25472942 DOI: 10.1158/2159-8290.CD-14-1156  0.32
2015 Dyment DA, Tétreault M, Beaulieu CL, Hartley T, Ferreira P, Chardon JW, Marcadier J, Sawyer SL, Mosca SJ, Innes AM, Parboosingh JS, Bulman DE, Schwartzentruber J, Majewski J, Tarnopolsky M, et al. Whole-exome sequencing broadens the phenotypic spectrum of rare pediatric epilepsy: a retrospective study. Clinical Genetics. 88: 34-40. PMID 25046240 DOI: 10.1111/cge.12464  0.32
2014 Lou DI, McBee RM, Le UQ, Stone AC, Wilkerson GK, Demogines AM, Sawyer SL. Rapid evolution of BRCA1 and BRCA2 in humans and other primates. Bmc Evolutionary Biology. 14: 155. PMID 25011685 DOI: 10.1186/1471-2148-14-155  1
2014 Peng L, Adler M, Demogines A, Borrell A, Liu H, Tao L, Tepp WH, Zhang SC, Johnson EA, Sawyer SL, Dong M. Widespread sequence variations in VAMP1 across vertebrates suggest a potential selective pressure from botulinum neurotoxins. Plos Pathogens. 10: e1004177. PMID 25010769 DOI: 10.1371/journal.ppat.1004177  1
2014 White TE, Brandariz-Nuñez A, Valle-Casuso JC, Knowlton C, Kim B, Sawyer SL, Diaz-Griffero F. Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. Virology. 460: 34-44. PMID 25010268 DOI: 10.1016/j.virol.2014.04.023  1
2014 Hussmann JA, Lou DI, Sawyer SL, Press WH. Reply to Schmitt et al.: Data-filtering schemes for avoiding double-counting in circle sequencing. Proceedings of the National Academy of Sciences of the United States of America. 111: E1561. PMID 24877228 DOI: 10.1073/pnas.1402606111  1
2014 Meyerson NR, Rowley PA, Swan CH, Le DT, Wilkerson GK, Sawyer SL. Positive selection of primate genes that promote HIV-1 replication. Virology. 454: 291-8. PMID 24725956 DOI: 10.1016/j.virol.2014.02.029  1
2014 Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, ... ... Sawyer SL, et al. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biology. 15: R53. PMID 24667040 DOI: 10.1186/gb-2014-15-3-r53  0.32
2014 Meyer AG, Sawyer SL, Ellington AD, Wilke CO. Analyzing machupo virus-receptor binding by molecular dynamics simulations. Peerj. 2: e266. PMID 24624315 DOI: 10.7717/peerj.266  1
2014 Boycott KM, Dyment DA, Sawyer SL, Vanstone MR, Beaulieu CL. Identification of genes for childhood heritable diseases. Annual Review of Medicine. 65: 19-31. PMID 24422568 DOI: 10.1146/annurev-med-101712-122108  0.32
2014 Sawyer SL, Schwartzentruber J, Beaulieu CL, Dyment D, Smith A, Warman Chardon J, Yoon G, Rouleau GA, Suchowersky O, Siu V, Murphy L, Hegele RA, Marshall CR, Bulman DE, et al. Exome sequencing as a diagnostic tool for pediatric-onset ataxia. Human Mutation. 35: 45-9. PMID 24108619 DOI: 10.1002/humu.22451  0.32
2013 Lou DI, Hussmann JA, McBee RM, Acevedo A, Andino R, Press WH, Sawyer SL. High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing. Proceedings of the National Academy of Sciences of the United States of America. 110: 19872-7. PMID 24243955 DOI: 10.1073/pnas.1319590110  1
2013 Malfavon-Borja R, Sawyer SL, Wu LI, Emerman M, Malik HS. An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family. Genome Biology and Evolution. 5: 2141-54. PMID 24158625 DOI: 10.1093/gbe/evt163  1
2013 Dyment DA, Sawyer SL, Chardon JW, Boycott KM. Recent advances in the genetic etiology of brain malformations. Current Neurology and Neuroscience Reports. 13: 364. PMID 23793931 DOI: 10.1007/s11910-013-0364-1  0.32
2013 Abrams AJ, Cannatella DC, Hillis DM, Sawyer SL. Recent host-shifts in ranaviruses: signatures of positive selection in the viral genome. The Journal of General Virology. 94: 2082-93. PMID 23784445 DOI: 10.1099/vir.0.052837-0  1
2013 Demogines A, Abraham J, Choe H, Farzan M, Sawyer SL. Dual host-virus arms races shape an essential housekeeping protein. Plos Biology. 11: e1001571. PMID 23723737 DOI: 10.1371/journal.pbio.1001571  1
2013 McDougle RM, Hultquist JF, Stabell AC, Sawyer SL, Harris RS. D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B. Virology. 441: 31-9. PMID 23542011 DOI: 10.1016/j.virol.2013.03.003  1
2013 Sawyer SL, Dicke F, Kirton A, Rajapkse T, Rebeyka IM, McInnes B, Parboosingh JS, Bernier FP. Longer term survival of a child with autosomal recessive cutis laxa due to a mutation in FBLN4. American Journal of Medical Genetics. Part A. 161: 1148-53. PMID 23532871 DOI: 10.1002/ajmg.a.35827  0.32
2013 Voit RA, McMahon MA, Sawyer SL, Porteus MH. Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 786-95. PMID 23358186 DOI: 10.1038/mt.2012.284  1
2013 Sawyer SL, Fogle SR. Establishment of a new breeding colony of Australasian gannets (Morus serrator) at Young Nick's Head Peninsula Notornis. 60: 180-182.  0.4
2012 Sawyer SL, Elde NC. A cross-species view on viruses. Current Opinion in Virology. 2: 561-8. PMID 22835485 DOI: 10.1016/j.coviro.2012.07.003  1
2012 Kaelber JT, Demogines A, Harbison CE, Allison AB, Goodman LB, Ortega AN, Sawyer SL, Parrish CR. Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs. Plos Pathogens. 8: e1002666. PMID 22570610 DOI: 10.1371/journal.ppat.1002666  1
2012 Demogines A, Farzan M, Sawyer SL. Evidence for ACE2-utilizing coronaviruses (CoVs) related to severe acute respiratory syndrome CoV in bats. Journal of Virology. 86: 6350-3. PMID 22438550 DOI: 10.1128/JVI.00311-12  1
2012 Lee K, Mulky A, Yuen W, Martin TD, Meyerson NR, Choi L, Yu H, Sawyer SL, Kewalramani VN. HIV-1 capsid-targeting domain of cleavage and polyadenylation specificity factor 6. Journal of Virology. 86: 3851-60. PMID 22301135 DOI: 10.1128/JVI.06607-11  1
2012 Demogines A, Truong KA, Sawyer SL. Species-specific features of DARC, the primate receptor for Plasmodium vivax and Plasmodium knowlesi. Molecular Biology and Evolution. 29: 445-9. PMID 21878684 DOI: 10.1093/molbev/msr204  1
2011 Han K, Lou DI, Sawyer SL. Identification of a genomic reservoir for new TRIM genes in primate genomes. Plos Genetics. 7: e1002388. PMID 22144910 DOI: 10.1371/journal.pgen.1002388  1
2011 Meyerson NR, Sawyer SL. Two-stepping through time: mammals and viruses. Trends in Microbiology. 19: 286-94. PMID 21531564 DOI: 10.1016/j.tim.2011.03.006  1
2010 Demogines A, East AM, Lee JH, Grossman SR, Sabeti PC, Paull TT, Sawyer SL. Ancient and recent adaptive evolution of primate non-homologous end joining genes. Plos Genetics. 6: e1001169. PMID 20975951 DOI: 10.1371/journal.pgen.1001169  1
2010 Sawyer SL, Fogle SR. Acoustic attraction of grey-faced petrels (Pterodroma macroptera gouldi) and fluttering shearwaters (Puffinus gavia) to Young nick's Head New Zealand Notornis. 57: 166-168.  0.4
2009 Johnson WE, Sawyer SL. Molecular evolution of the antiretroviral TRIM5 gene. Immunogenetics. 61: 163-76. PMID 19238338 DOI: 10.1007/s00251-009-0358-y  1
2009 Tareen SU, Sawyer SL, Malik HS, Emerman M. An expanded clade of rodent Trim5 genes. Virology. 385: 473-83. PMID 19147168 DOI: 10.1016/j.virol.2008.12.018  1
2007 Sawyer SL, Emerman M, Malik HS. Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. Plos Pathogens. 3: e197. PMID 18159944 DOI: 10.1371/journal.ppat.0030197  1
2006 Sawyer SL, Malik HS. Positive selection of yeast nonhomologous end-joining genes and a retrotransposon conflict hypothesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 17614-9. PMID 17101967 DOI: 10.1073/pnas.0605468103  1
2006 Fredman D, Sawyer SL, Strömqvist L, Mottagui-Tabar S, Kidd KK, Wahlestedt C, Chanock SJ, Brookes AJ. Nonsynonymous SNPs: validation characteristics, derived allele frequency patterns, and suggestive evidence for natural selection. Human Mutation. 27: 173-86. PMID 16429399 DOI: 10.1002/humu.20289  0.32
2006 Sawyer SL, Wu LI, Akey JM, Emerman M, Malik HS. High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Current Biology : Cb. 16: 95-100. PMID 16401428 DOI: 10.1016/j.cub.2005.11.045  1
2005 Sawyer SL, Wu LI, Emerman M, Malik HS. Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proceedings of the National Academy of Sciences of the United States of America. 102: 2832-7. PMID 15689398 DOI: 10.1073/pnas.0409853102  1
2005 Sawyer SL, Mukherjee N, Pakstis AJ, Feuk L, Kidd JR, Brookes AJ, Kidd KK. Linkage disequilibrium patterns vary substantially among populations. European Journal of Human Genetics : Ejhg. 13: 677-86. PMID 15657612 DOI: 10.1038/sj.ejhg.5201368  0.32
2004 Liu N, Sawyer SL, Mukherjee N, Pakstis AJ, Kidd JR, Kidd KK, Brookes AJ, Zhao H. Haplotype block structures show significant variation among populations. Genetic Epidemiology. 27: 385-400. PMID 15389924 DOI: 10.1002/gepi.20026  0.32
2004 Sawyer SL, Emerman M, Malik HS. Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. Plos Biology. 2: E275. PMID 15269786 DOI: 10.1371/journal.pbio.0020275  1
2004 Sawyer SL, Cheng IH, Chai W, Tye BK. Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae. Journal of Molecular Biology. 340: 195-202. PMID 15201046 DOI: 10.1016/j.jmb.2004.04.066  1
2003 Sawyer SL, Howell WM, Brookes AJ. Scoring insertion-deletion polymorphisms by dynamic allele-specific hybridization. Biotechniques. 35: 292-6, 298. PMID 12951770  0.32
2003 Sawyer SL, Berglind LC, Brookes AJ. Negligible validation rate for public domain stop-codon SNPs. Human Mutation. 22: 252-4. PMID 12938090 DOI: 10.1002/humu.10256  0.32
2001 Prince JA, Feuk L, Sawyer SL, Gottfries J, Ricksten A, Nägga K, Bogdanovic N, Blennow K, Brookes AJ. Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease. European Journal of Human Genetics : Ejhg. 9: 437-44. PMID 11436125 DOI: 10.1038/sj.ejhg.5200651  0.32
2001 Emahazion T, Feuk L, Jobs M, Sawyer SL, Fredman D, St Clair D, Prince JA, Brookes AJ. SNP association studies in Alzheimer's disease highlight problems for complex disease analysis. Trends in Genetics : Tig. 17: 407-13. PMID 11418222 DOI: 10.1016/S0168-9525(01)02342-3  0.32
2000 Tye BK, Sawyer S. The hexameric eukaryotic MCM helicase: Building symmetry from nonidentical parts Journal of Biological Chemistry. 275: 34833-34836. PMID 10980206 DOI: 10.1074/jbc.R000018200  1
2000 Homesley L, Lei M, Kawasaki Y, Sawyer S, Christensen T, Tye BK. Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins Genes and Development. 14: 913-926. PMID 10783164  1
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