Karen M. Lyons - Publications

Affiliations: 
Molec, Cell, & Dev Biology 0644 University of California, Los Angeles, Los Angeles, CA 
Area:
Human Development, Evolution and Development Biology

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhao G, Kim EW, Jiang J, Bhoot C, Charles KR, Baek J, Mohan S, Adams JS, Tetradis S, Lyons KM. CCN1/Cyr61 is required in osteoblasts for responsiveness to the anabolic activity of PTH. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32634285 DOI: 10.1002/jbmr.4128  0.32
2020 Wang W, Rigueur D, Lyons KM. TGFβ as a gatekeeper of BMP action in the developing growth plate. Bone. 115439. PMID 32442550 DOI: 10.1016/j.bone.2020.115439  0.4
2019 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM. The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage. Proceedings of the National Academy of Sciences of the United States of America. PMID 31311865 DOI: 10.1073/pnas.1902927116  0.4
2018 Jiang J, Zhao G, Lyons KM. Correction to: Characterization of bone morphology in CCN5/WISP2 knockout mice. Journal of Cell Communication and Signaling. PMID 29455304 DOI: 10.1007/s12079-018-0463-5  0.32
2018 Jiang J, Zhao G, Lyons KM. Characterization bone morphology in CCN5/WISP5 knockout mice. Journal of Cell Communication and Signaling. PMID 29396648 DOI: 10.1007/s12079-018-0457-3  0.32
2018 Zhao G, Huang BL, Rigueur D, Wang W, Bhoot C, Charles KR, Baek J, Mohan S, Jiang J, Lyons KM. CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29351359 DOI: 10.1002/jbmr.3394  0.92
2017 Burga A, Wang W, Ben-David E, Wolf PC, Ramey AM, Verdugo C, Lyons K, Parker PG, Kruglyak L. A genetic signature of the evolution of loss of flight in the Galapagos cormorant. Science (New York, N.Y.). 356. PMID 28572335 DOI: 10.1126/Science.Aal3345  0.4
2017 Zhang Y, Huang H, Zhao G, Yokoyama T, Vega H, Huang Y, Sood R, Bishop K, Maduro V, Accardi J, Toro C, Boerkoel CF, Lyons K, Gahl WA, Duan X, et al. Correction: ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13. Plos Genetics. 13: e1006624. PMID 28241013 DOI: 10.1371/journal.pgen.1006624  0.32
2017 Zhang Y, Huang H, Zhao G, Yokoyama T, Vega H, Huang Y, Sood R, Bishop K, Maduro V, Accardi J, Toro C, Boerkoel CF, Lyons K, Gahl WA, Duan X, et al. ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13. Plos Genetics. 13: e1006481. PMID 28158191 DOI: 10.1371/journal.pgen.1006481  0.32
2017 Jiang J, Hu Z, Lyons KM. Design and Analysis of CCN Gene Activity Using CCN Knockout Mice Containing LacZ Reporters. Methods in Molecular Biology (Clifton, N.J.). 1489: 325-345. PMID 27734387 DOI: 10.1007/978-1-4939-6430-7_28  1
2016 Wang W, Song B, Anbarchian T, Shirazyan A, Sadik JE, Lyons KM. Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. Plos Genetics. 12: e1006352. PMID 27741240 DOI: 10.1371/journal.pgen.1006352  0.52
2016 Zieba J, Forlenza KN, Khatra JS, Sarukhanov A, Duran I, Rigueur D, Lyons KM, Cohn DH, Merrill AE, Krakow D. TGFβ and BMP Dependent Cell Fate Changes Due to Loss of Filamin B Produces Disc Degeneration and Progressive Vertebral Fusions. Plos Genetics. 12: e1005936. PMID 27019229 DOI: 10.1371/journal.pgen.1005936  1
2015 Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard-O'Riley R, Wilson TL, Sandusky G, Abadie J, Lyons KM, Giaccia AJ, Schipani E. Fibrosis and Hypoxia-Inducible Factor-1α-Dependent Tumors of the Soft Tissue on Loss of Von Hippel-Lindau in Mesenchymal Progenitors. The American Journal of Pathology. 185: 3090-101. PMID 26348575 DOI: 10.1016/j.ajpath.2015.07.008  1
2015 Maeda A, Ono M, Holmbeck K, Li L, Kilts TM, Kram V, Noonan ML, Yoshioka Y, McNerny EM, Tantillo MA, Kohn DH, Lyons KM, Robey PG, Young MF. WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling. The Journal of Biological Chemistry. 290: 14004-18. PMID 25864198 DOI: 10.1074/Jbc.M114.628818  1
2015 Rigueur D, Brugger S, Anbarchian T, Kim JK, Lee Y, Lyons KM. The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 733-41. PMID 25413979 DOI: 10.1002/jbmr.2385  1
2015 Nishida T, Kubota S, Aoyama E, Janune D, Lyons KM, Takigawa M. CCN family protein 2 (CCN2) promotes the early differentiation, but inhibits the terminal differentiation of skeletal myoblasts. Journal of Biochemistry. 157: 91-100. PMID 25261584 DOI: 10.1093/jb/mvu056  1
2014 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML. Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental Cell. 31: 707-21. PMID 25535917 DOI: 10.1016/J.Devcel.2014.11.023  1
2014 Ascenzi M, Du X, Harding JI, Beylerian EN, de Silva BM, Gross BJ, Kastein HK, Wang W, Lyons KM, Schaeffer H. Automated Cell Detection and Morphometry on Growth Plate Images of Mouse Bone. Applied Mathematics. 5: 2866-2880. PMID 25525552 DOI: 10.4236/am.2014.518273  0.4
2014 Cheung LC, Strickland DH, Howlett M, Ford J, Charles AK, Lyons KM, Brigstock DR, Goldschmeding R, Cole CH, Alexander WS, Kees UR. Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis. Haematologica. 99: 1149-56. PMID 24727816 DOI: 10.3324/haematol.2013.102327  1
2014 Wang W, Rigueur D, Lyons KM. TGFβ signaling in cartilage development and maintenance. Birth Defects Research. Part C, Embryo Today : Reviews. 102: 37-51. PMID 24677722 DOI: 10.1002/bdrc.21058  1
2014 Rigueur D, Lyons KM. Whole-mount skeletal staining. Methods in Molecular Biology (Clifton, N.J.). 1130: 113-21. PMID 24482169 DOI: 10.1007/978-1-62703-989-5_9  1
2014 Maeda-Uematsu A, Kubota S, Kawaki H, Kawata K, Miyake Y, Hattori T, Nishida T, Moritani N, Lyons KM, Iida S, Takigawa M. CCN2 as a novel molecule supporting energy metabolism of chondrocytes. Journal of Cellular Biochemistry. 115: 854-65. PMID 24288211 DOI: 10.1002/jcb.24728  1
2013 Wu L, Bluguermann C, Kyupelyan L, Latour B, Gonzalez S, Shah S, Galic Z, Ge S, Zhu Y, Petrigliano FA, Nsair A, Miriuka SG, Li X, Lyons KM, Crooks GM, et al. Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells. Stem Cell Reports. 1: 575-89. PMID 24371811 DOI: 10.1016/j.stemcr.2013.10.012  1
2013 Estrada KD, Wang W, Retting KN, Chien CT, Elkhoury FF, Heuchel R, Lyons KM. Smad7 regulates terminal maturation of chondrocytes in the growth plate. Developmental Biology. 382: 375-84. PMID 23994637 DOI: 10.1016/j.ydbio.2013.08.021  1
2013 Battula VL, Chen Y, Cabreira Mda G, Ruvolo V, Wang Z, Ma W, Konoplev S, Shpall E, Lyons K, Strunk D, Bueso-Ramos C, Davis RE, Konopleva M, Andreeff M. Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment. Blood. 122: 357-66. PMID 23741006 DOI: 10.1182/blood-2012-06-437988  1
2013 Hall-Glenn F, Aivazi A, Akopyan L, Ong JR, Baxter RR, Benya PD, Goldschmeding R, van Nieuwenhoven FA, Hunziker EB, Lyons KM. CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress. Journal of Cell Communication and Signaling. 7: 219-30. PMID 23666466 DOI: 10.1007/s12079-013-0201-y  1
2013 Tran CM, Fujita N, Huang BL, Ong JR, Lyons KM, Shapiro IM, Risbud MV. Hypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity. The Journal of Biological Chemistry. 288: 12654-66. PMID 23530034 DOI: 10.1074/jbc.M112.448860  1
2012 Falke LL, Dendooven A, Leeuwis JW, Nguyen TQ, van Geest RJ, van der Giezen DM, Broekhuizen R, Lyons K, Stoop R, Kemperman H, Schlingemann R, Joles JA, Goldschmeding R. Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 421-31. PMID 23199377 DOI: 10.1016/j.matbio.2012.06.002  1
2012 Merrill AE, Sarukhanov A, Krejci P, Idoni B, Camacho N, Estrada KD, Lyons KM, Deixler H, Robinson H, Chitayat D, Curry CJ, Lachman RS, Wilcox WR, Krakow D. Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling. American Journal of Human Genetics. 90: 550-7. PMID 22387015 DOI: 10.1016/j.ajhg.2012.02.005  1
2012 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM. CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. Plos One. 7: e30562. PMID 22363445 DOI: 10.1371/Journal.Pone.0030562  1
2011 Nagashima T, Kim J, Li Q, Lydon JP, DeMayo FJ, Lyons KM, Matzuk MM. Connective tissue growth factor is required for normal follicle development and ovulation. Molecular Endocrinology (Baltimore, Md.). 25: 1740-59. PMID 21868453 DOI: 10.1210/me.2011-1045  1
2011 Hall-Glenn F, Lyons KM. Roles for CCN2 in normal physiological processes. Cellular and Molecular Life Sciences : Cmls. 68: 3209-17. PMID 21858450 DOI: 10.1007/s00018-011-0782-7  1
2011 Ascenzi MG, Blanco C, Drayer I, Kim H, Wilson R, Retting KN, Lyons KM, Mohler G. Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization. Journal of Theoretical Biology. 285: 147-55. PMID 21723296 DOI: 10.1016/J.Jtbi.2011.06.016  1
2011 Estrada KD, Retting KN, Chin AM, Lyons KM. Smad6 is essential to limit BMP signaling during cartilage development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2498-510. PMID 21681813 DOI: 10.1002/jbmr.443  1
2011 Chien W, O'Kelly J, Lu D, Leiter A, Sohn J, Yin D, Karlan B, Vadgama J, Lyons KM, Koeffler HP. Expression of connective tissue growth factor (CTGF/CCN2) in breast cancer cells is associated with increased migration and angiogenesis. International Journal of Oncology. 38: 1741-7. PMID 21455569 DOI: 10.3892/ijo.2011.985  1
2011 Suwanwela J, Farber CR, Haung BL, Song B, Pan C, Lyons KM, Lusis AJ. Systems genetics analysis of mouse chondrocyte differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 747-60. PMID 20954177 DOI: 10.1002/jbmr.271  1
2011 Nishida T, Emura K, Kubota S, Lyons KM, Takigawa M. CCN family 2/connective tissue growth factor (CCN2/CTGF) promotes osteoclastogenesis via induction of and interaction with dendritic cell-specific transmembrane protein (DC-STAMP). Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 351-63. PMID 20721934 DOI: 10.1002/jbmr.222  1
2010 Ohyama T, Basch ML, Mishina Y, Lyons KM, Segil N, Groves AK. BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15044-51. PMID 21068310 DOI: 10.1523/Jneurosci.3547-10.2010  1
2010 Huang BL, Brugger SM, Lyons KM. Stage-specific control of connective tissue growth factor (CTGF/CCN2) expression in chondrocytes by Sox9 and beta-catenin. The Journal of Biological Chemistry. 285: 27702-12. PMID 20571031 DOI: 10.1074/jbc.M110.108498  1
2010 Stevens JR, Miranda-Carboni GA, Singer MA, Brugger SM, Lyons KM, Lane TF. Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 2138-47. PMID 20499361 DOI: 10.1002/jbmr.118  1
2010 Edson MA, Nalam RL, Clementi C, Franco HL, Demayo FJ, Lyons KM, Pangas SA, Matzuk MM. Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development. Molecular Endocrinology (Baltimore, Md.). 24: 1251-66. PMID 20363875 DOI: 10.1210/me.2009-0461  1
2010 Lyons KM, Wang W. Leading-edge velocities and lifted methane jet flame stability Journal of Combustion. 2010. DOI: 10.1155/2010/612892  0.4
2010 Retting KN, Lyons KM. BMPs in development Handbook of Cell Signaling, 2/E. 2: 1905-1912. DOI: 10.1016/B978-0-12-374145-5.00233-3  1
2010 Takigawa M, Kawaki H, Kubota S, Lyons KM, Perbal B. Cooperative regulation of cell proliferation and differentiation by CCN2 and CCN3 Ccn Proteins in Health and Disease: An Overview of the Fifth International Workshop On the Ccn Family of Genes. 105-109. DOI: 10.1007/978-90-481-3779-4_8  1
2009 Song B, Estrada KD, Lyons KM. Smad signaling in skeletal development and regeneration. Cytokine & Growth Factor Reviews. 20: 379-88. PMID 19926329 DOI: 10.1016/j.cytogfr.2009.10.010  1
2009 Lyons K, Ezaki M. Molecular regulation of limb growth. The Journal of Bone and Joint Surgery. American Volume. 91: 47-52. PMID 19571067 DOI: 10.2106/JBJS.I.00240  1
2009 Turk T, Leeuwis JW, Gray J, Torti SV, Lyons KM, Nguyen TQ, Goldschmeding R. BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 57: 623-31. PMID 19255250 DOI: 10.1369/jhc.2009.953224  1
2009 Retting KN, Song B, Yoon BS, Lyons KM. BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development (Cambridge, England). 136: 1093-104. PMID 19224984 DOI: 10.1242/dev.029926  1
2009 Crawford LA, Guney MA, Oh YA, Deyoung RA, Valenzuela DM, Murphy AJ, Yancopoulos GD, Lyons KM, Brigstock DR, Economides A, Gannon M. Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis. Molecular Endocrinology (Baltimore, Md.). 23: 324-36. PMID 19131512 DOI: 10.1210/me.2008-0045  1
2009 Maeda A, Nishida T, Aoyama E, Kubota S, Lyons KM, Kuboki T, Takigawa M. CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes. Journal of Biochemistry. 145: 207-16. PMID 19038999 DOI: 10.1093/jb/mvn159  1
2009 Nishida T, Kondo S, Maeda A, Kubota S, Lyons KM, Takigawa M. CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1alpha expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition. Bone. 44: 24-31. PMID 18835464 DOI: 10.1016/j.bone.2008.08.125  1
2009 Lyons K. Animal Models: Genetic Manipulation Primer On the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Seventh Edition. 45-51. DOI: 10.1002/9780470623992.ch8  1
2008 Nguyen TQ, Roestenberg P, van Nieuwenhoven FA, Bovenschen N, Li Z, Xu L, Oliver N, Aten J, Joles JA, Vial C, Brandan E, Lyons KM, Goldschmeding R. CTGF inhibits BMP-7 signaling in diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 19: 2098-107. PMID 18632843 DOI: 10.1681/ASN.2007111261  1
2008 Sengle G, Ono RN, Lyons KM, Bächinger HP, Sakai LY. A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. Journal of Molecular Biology. 381: 1025-39. PMID 18621057 DOI: 10.1016/j.jmb.2008.06.074  1
2008 Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M. Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 1751-64. PMID 18597638 DOI: 10.1359/jbmr.080615  1
2008 Kuiper EJ, van Zijderveld R, Roestenberg P, Lyons KM, Goldschmeding R, Klaassen I, Van Noorden CJ, Schlingemann RO. Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 56: 785-92. PMID 18474939 DOI: 10.1369/jhc.2008.950980  1
2008 Pala D, Kapoor M, Woods A, Kennedy L, Liu S, Chen S, Bursell L, Lyons KM, Carter DE, Beier F, Leask A. Focal adhesion kinase/Src suppresses early chondrogenesis: central role of CCN2. The Journal of Biological Chemistry. 283: 9239-47. PMID 18276598 DOI: 10.1074/jbc.M705175200  1
2008 Pacheco MS, Reis AH, Aguiar DP, Lyons KM, Abreu JG. Dynamic analysis of the expression of the TGFbeta/SMAD2 pathway and CCN2/CTGF during early steps of tooth development. Cells, Tissues, Organs. 187: 199-210. PMID 18089935 DOI: 10.1159/000112640  1
2008 Kawaki H, Kubota S, Suzuki A, Yamada T, Matsumura T, Mandai T, Yao M, Maeda T, Lyons KM, Takigawa M. Functional requirement of CCN2 for intramembranous bone formation in embryonic mice. Biochemical and Biophysical Research Communications. 366: 450-6. PMID 18067859 DOI: 10.1016/j.bbrc.2007.11.155  1
2008 Rosen V, Gamer LW, Lyons KM. Bone Morphogenetic Proteins and the Skeleton Principles of Bone Biology, Two-Volume Set. 2: 1167-1175. DOI: 10.1016/B978-0-12-373884-4.00068-9  1
2007 Nishida T, Kawaki H, Baxter RM, Deyoung RA, Takigawa M, Lyons KM. CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes. Journal of Cell Communication and Signaling. 1: 45-58. PMID 18481209 DOI: 10.1007/s12079-007-0005-z  1
2007 Huang BL, Dornbach LM, Lyons KM. The 5' untranslated regions (UTRs) of CCN1, CCN2, and CCN4 exhibit cryptic promoter activity. Journal of Cell Communication and Signaling. 1: 17-32. PMID 18481207 DOI: 10.1007/s12079-007-0003-1  1
2007 Kuiper EJ, Roestenberg P, Ehlken C, Lambert V, van Treslong-de Groot HB, Lyons KM, Agostini HJ, Rakic JM, Klaassen I, Van Noorden CJ, Goldschmeding R, Schlingemann RO. Angiogenesis is not impaired in connective tissue growth factor (CTGF) knock-out mice. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 55: 1139-47. PMID 17625227 DOI: 10.1369/jhc.7A7258.2007  1
2007 Kennedy L, Liu S, Shi-Wen X, Chen Y, Eastwood M, Sabetkar M, Carter DE, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for the function of mouse embryonic fibroblasts. Experimental Cell Research. 313: 952-64. PMID 17239853 DOI: 10.1016/j.yexcr.2006.12.006  1
2007 Kennedy L, Liu S, Shi-wen X, Chen Y, Eastwood M, Sabetkar M, Carter DE, Lyons KM, Black CM, Abraham DJ, Leask A. Corrigendum to "CCN2 is necessary for the function of mouse embryonic fibroblasts" [Exp. Cell Res. 313 (2007) 952-964] (DOI:10.1016/j.yexcr.2006.12.006) Experimental Cell Research. 313: 3671. DOI: 10.1016/j.yexcr.2007.06.016  1
2006 Pogue R, Lyons K. BMP Signaling in the Cartilage Growth Plate Current Topics in Developmental Biology. 76: 1-48. PMID 17118262 DOI: 10.1016/S0070-2153(06)76001-X  1
2006 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM. BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways Development. 133: 4667-4678. PMID 17065231 DOI: 10.1242/Dev.02680  1
2006 Wan DC, Shi YY, Nacamuli RP, Quarto N, Lyons KM, Longaker MT. Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 12335-40. PMID 16894153 DOI: 10.1073/pnas.0604849103  1
2006 Gamradt SC, Abe N, Bahamonde ME, Lee YP, Nelson SD, Lyons KM, Lieberman JR. Tracking expression of virally mediated BMP-2 in gene therapy for bone repair. Clinical Orthopaedics and Related Research. 450: 238-45. PMID 16702923 DOI: 10.1097/01.blo.0000223989.49400.a8  1
2006 Merrill AE, Bochukova EG, Brugger SM, Ishii M, Pilz DT, Wall SA, Lyons KM, Wilkie AO, Maxson RE. Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis. Human Molecular Genetics. 15: 1319-28. PMID 16540516 DOI: 10.1093/hmg/ddl052  1
2006 Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton RJ, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, et al. CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. The Journal of Biological Chemistry. 281: 10715-26. PMID 16484225 DOI: 10.1074/jbc.M511343200  1
2005 Kobayashi T, Lyons KM, McMahon AP, Kronenberg HM. BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proceedings of the National Academy of Sciences of the United States of America. 102: 18023-7. PMID 16322106 DOI: 10.1073/Pnas.0503617102  1
2005 Lee NV, Rodriguez-Manzaneque JC, Thai SN, Twal WO, Luque A, Lyons KM, Argraves WS, Iruela-Arispe ML. Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. The Journal of Biological Chemistry. 280: 34796-804. PMID 16061471 DOI: 10.1074/Jbc.M506980200  1
2005 Kim J, Wu HH, Lander AD, Lyons KM, Matzuk MM, Calof AL. GDF11 controls the timing of progenitor cell competence in developing retina. Science (New York, N.Y.). 308: 1927-30. PMID 15976303 DOI: 10.1126/Science.1110175  1
2005 Zakin L, Reversade B, Kuroda H, Lyons KM, De Robertis EM. Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development (Cambridge, England). 132: 2489-99. PMID 15843411 DOI: 10.1242/dev.01822  1
2005 Yoon BS, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM. Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo Proceedings of the National Academy of Sciences of the United States of America. 102: 5062-5067. PMID 15781876 DOI: 10.1073/Pnas.0500031102  1
2005 Murali D, Yoshikawa S, Corrigan RR, Plas DJ, Crair MC, Oliver G, Lyons KM, Mishina Y, Furuta Y. Distinct developmental programs require different levels of Bmp signaling during mouse retinal development. Development (Cambridge, England). 132: 913-23. PMID 15673568 DOI: 10.1242/dev.01673  1
2004 Wine-Lee L, Ahn KJ, Richardson RD, Mishina Y, Lyons KM, Crenshaw EB. Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development (Cambridge, England). 131: 5393-403. PMID 15469980 DOI: 10.1242/dev.01379  1
2004 Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL. Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 542-50. PMID 15376321 DOI: 10.1002/dvdy.20162  1
2004 Chen Y, Abraham DJ, Shi-Wen X, Pearson JD, Black CM, Lyons KM, Leask A. CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin. Molecular Biology of the Cell. 15: 5635-46. PMID 15371538 DOI: 10.1091/mbc.E04-06-0490  1
2004 Yoon BS, Lyons KM. Multiple functions of BMPs in chondrogenesis. Journal of Cellular Biochemistry. 93: 93-103. PMID 15352166 DOI: 10.1002/jcb.20211  1
2004 Andl T, Ahn K, Kairo A, Chu EY, Wine-Lee L, Reddy ST, Croft NJ, Cebra-Thomas JA, Metzger D, Chambon P, Lyons KM, Mishina Y, Seykora JT, Crenshaw EB, Millar SE. Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (Cambridge, England). 131: 2257-68. PMID 15102710 DOI: 10.1242/Dev.01125  1
2003 Nishimura I, Drake TA, Lusis AJ, Lyons KM, Nadeau JH, Zernik J. ENU large-scale mutagenesis and quantitative trait linkage (QTL) analysis in mice: novel technologies for searching polygenetic determinants of craniofacial abnormalities. Critical Reviews in Oral Biology and Medicine : An Official Publication of the American Association of Oral Biologists. 14: 320-30. PMID 14530301 DOI: 10.1177/154411130301400503  1
2003 Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM. Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development (Cambridge, England). 130: 2779-91. PMID 12736220 DOI: 10.1242/Dev.00505  1
2003 Wu HH, Ivkovic S, Murray RC, Jaramillo S, Lyons KM, Johnson JE, Calof AL. Autoregulation of neurogenesis by GDF11. Neuron. 37: 197-207. PMID 12546816 DOI: 10.1016/S0896-6273(02)01172-8  1
2003 Schneider MD, Gaussin V, Lyons KM. Tempting fate: BMP signals for cardiac morphogenesis. Cytokine & Growth Factor Reviews. 14: 1-4. PMID 12485614 DOI: 10.1016/S1359-6101(02)00053-9  1
2003 Délot EC, Bahamonde ME, Zhao M, Lyons KM. BMP signaling is required for septation of the outflow tract of the mammalian heart. Development (Cambridge, England). 130: 209-20. PMID 12441304 DOI: 10.1242/dev.00181  1
2001 Yi SE, LaPolt PS, Yoon BS, Chen JY, Lu JK, Lyons KM. The type I BMP receptor BmprIB is essential for female reproductive function. Proceedings of the National Academy of Sciences of the United States of America. 98: 7994-9. PMID 11416163 DOI: 10.1073/pnas.141002798  1
2001 Clarke TR, Hoshiya Y, Yi SE, Liu X, Lyons KM, Donahoe PK. Müllerian inhibiting substance signaling uses a bone morphogenetic protein (BMP)-like pathway mediated by ALK2 and induces SMAD6 expression. Molecular Endocrinology (Baltimore, Md.). 15: 946-59. PMID 11376113 DOI: 10.1210/mend.15.6.0664  1
2001 Bahamonde ME, Lyons KM. BMP3: to be or not to be a BMP. The Journal of Bone and Joint Surgery. American Volume. 83: S56-62. PMID 11263666  1
2001 Daluiski A, Yi SE, Lyons KM. The molecular control of upper extremity development: implications for congenital hand anomalies. The Journal of Hand Surgery. 26: 8-22. PMID 11172363 DOI: 10.1053/jhsu.2001.9419  1
2001 Daluiski A, Engstrand T, Bahamonde ME, Gamer LW, Agius E, Stevenson SL, Cox K, Rosen V, Lyons KM. Bone morphogenetic protein-3 is a negative regulator of bone density. Nature Genetics. 27: 84-8. PMID 11138004 DOI: 10.1038/83810  1
2001 Bahamonde ME, Lyons KM. BMP3: To be or not to be a BMP Journal of Bone and Joint Surgery - Series A. 83.  1
2000 Engstrand T, Daluiski A, Bahamonde ME, Melhus H, Lyons KM. Transient production of bone morphogenetic protein 2 by allogeneic transplanted transduced cells induces bone formation. Human Gene Therapy. 11: 205-11. PMID 10646651 DOI: 10.1089/10430340050016274  1
2000 Yi SE, Daluiski A, Pederson R, Rosen V, Lyons KM. The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb. Development (Cambridge, England). 127: 621-30. PMID 10631182  1
1999 Li HH, Yu WH, Rozengurt N, Zhao HZ, Lyons KM, Anagnostaras S, Fanselow MS, Suzuki K, Vanier MT, Neufeld EF. Mouse model of Sanfilippo syndrome type B produced by targeted disruption of the gene encoding alpha-N-acetylglucosaminidase. Proceedings of the National Academy of Sciences of the United States of America. 96: 14505-10. PMID 10588735 DOI: 10.1073/Pnas.96.25.14505  1
1999 Nofziger D, Miyamoto A, Lyons KM, Weinmaster G. Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts Development. 126: 1689-1702. PMID 10079231  1
1998 Dube JL, Wang P, Elvin J, Lyons KM, Celeste AJ, Matzuk MM. The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes. Molecular Endocrinology (Baltimore, Md.). 12: 1809-17. PMID 9849956 DOI: 10.1210/mend.12.12.0206  1
1998 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BLM, Robertson EJ. Mice lacking Bmp6 function Developmental Genetics. 22: 321-339. PMID 9664685 DOI: 10.1002/(SICI)1520-6408(1998)22:4<321::AID-DVG3>3.0.CO;2-8  1
1996 Riley EH, Lane JM, Urist MR, Lyons KM, Lieberman JR. Bone morphogenetic protein-2: Biology and applications Clinical Orthopaedics and Related Research. 39-46. PMID 8595775  1
1995 Lyons KM, Hogan BLM, Robertson EJ. Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development Mechanisms of Development. 50: 71-83. PMID 7605753 DOI: 10.1016/0925-4773(94)00326-I  1
1995 Dudley AT, Lyons KM, Robertson EJ. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye Genes and Development. 9: 2795-2807. PMID 7590254  1
1994 Conlon FL, Lyons KM, Takaesu N, Barth KS, Kispert A, Herrmann B, Robertson EJ. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse Development. 120: 1919-1928. PMID 7924997  1
1992 Lyons KM, Jones CM, Hogan BL. The TGF-beta-related DVR gene family in mammalian development Ciba Foundation Symposium. 165: 219-230; discussion . PMID 1516470  1
1992 Jones CM, Lyons KM, Lapan PM, Wright CVE, Hogan BLM. DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction Development. 115: 639-647. PMID 1425343  1
1991 Jones CM, Lyons KM, Hogan BLM. Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse Development. 111: 531-542. PMID 1893873  1
1991 Lyons KM, Jones CM, Hogan BLM. The DVR gene family in embryonic development Trends in Genetics. 7: 408-412. PMID 1820688 DOI: 10.1016/0168-9525(91)90265-R  1
1991 Jones CM, Lyons KM, Hogan BLM. Expression of TGF-β-related genes during mouse embryo whisker morphogeneis Annals of the New York Academy of Sciences. 642: 339-345. PMID 1809091 DOI: 10.1111/j.1749-6632.1991.tb24399.x  1
1990 Lyons KM, Pelton RW, Hogan BLM. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A) Development. 109: 833-844. PMID 2226202  1
1990 Lyons KM. Turned on by activin New Biologist. 2: 527-531. PMID 1982424  1
1990 Dickinson ME, Kobrin MS, Silan CM, Kingsley DM, Justice MJ, Miller DA, Ceci JD, Lock LF, Lee A, Buchberg AM. Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci. Genomics. 6: 505-20. PMID 1970330 DOI: 10.1016/0888-7543(90)90480-I  1
1989 Lyons KM, Pelton RW, Hogan BL. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development Genes &Amp; Development. 3: 1657-1668. PMID 2481605  1
1988 Hogan B, Lyons K. Getting nearer the mark Nature. 336: 304-305. PMID 3194014 DOI: 10.1038/336304A0  1
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