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Dale Gene Drueckhammer - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 
Area:
organic chemistry
Website:
http://www.chem.stonybrook.edu/faculty/drueckhammer.shtml

39/73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Liao J, Drueckhammer DG. Diastereoselective conjugate addition/cyclization/bromination: Access to four stereocenters in a single step Tetrahedron Letters. 59: 1776-1778. DOI: 10.1016/J.Tetlet.2018.03.080  0.367
2014 Liang X, Drueckhammer DG. Arsinous acid as a thiol binding group: Potential cysteine peptide tagging functionality that binds a single thiol New Journal of Chemistry. 38: 1368-1371. DOI: 10.1039/C3Nj01462B  0.333
2010 Zhu Y, Drueckhammer DG. ChemInform Abstract: An Efficient Synthesis of Geminal Di-Sulfones. Cheminform. 33: no-no. DOI: 10.1002/chin.200223072  0.404
2010 MARTIN DP, BIBART RT, DRUECKHAMMER DG. ChemInform Abstract: Synthesis of Novel Analogues of Acetyl Coenzyme A: Mimics of Enzyme Reaction Intermediates. Cheminform. 25: no-no. DOI: 10.1002/chin.199443272  0.334
2007 Wang J, Zheng X, Yang Y, Drueckhammer D, Yang W, Verkhivker G, Wang E. Quantifying intrinsic specificity: a potential complement to affinity in drug screening. Physical Review Letters. 99: 198101. PMID 18233118 DOI: 10.1103/Physrevlett.99.198101  0.512
2007 Lin C, Simov V, Drueckhammer DG. Interaction of halide and carboxylate ions with 4,5-diacetamidoacridine-9(10H)-one: thermodynamics of association and deprotonation events. The Journal of Organic Chemistry. 72: 1742-6. PMID 17286443 DOI: 10.1021/Jo062467J  0.42
2006 Huang H, Drueckhammer DG. A modular molecular tweezer designed using CAVEAT. Chemical Communications (Cambridge, England). 2995-7. PMID 16832515 DOI: 10.1039/B605756J  0.491
2006 Lin C, Drueckhammer DG. Computer-guided design of a Cu(II) receptor and sensor New Journal of Chemistry. 30: 1725-1730. DOI: 10.1039/B610887C  0.401
2005 Yang Y, Nesterenko DV, Trump RP, Yamaguchi K, Bartlett PA, Drueckhammer DG. Virtual hydrocarbon and combinatorial databases for use with CAVEAT. Journal of Chemical Information and Modeling. 45: 1820-3. PMID 16309289 DOI: 10.1021/Ci050277O  0.475
2005 Huang H, Drueckhammer DG. A computer-designed macrocyclic zinc receptor. Chemical Communications (Cambridge, England). 5196-8. PMID 16228033 DOI: 10.1039/B508542J  0.489
2005 Zhu Y, Drueckhammer DG. Transition state modeling and catalyst design for hydrogen bond-stabilized enolate formation. The Journal of Organic Chemistry. 70: 7755-60. PMID 16149809 DOI: 10.1021/Jo0513818  0.487
2005 Xun J, Huang H, Vogel KW, Drueckhammer DG. The importance of the amide bond nearest the thiol group in enzymatic reactions of coenzyme A. Bioorganic Chemistry. 33: 90-107. PMID 15788165 DOI: 10.1016/J.Bioorg.2004.10.002  0.653
2003 Yang W, Drueckhammer DG. Computational study of the citrate synthase catalyzed deprotonation of acetyl-coenzyme A and fluoroacetyl-coenzyme A: Demonstration of a layered quantum mechanical approach Journal of Physical Chemistry B. 107: 5986-5994. DOI: 10.1021/Jp034717V  0.314
2002 Beaman TW, Vogel KW, Drueckhammer DG, Blanchard JS, Roderick SL. Acyl group specificity at the active site of tetrahydridipicolinate N-succinyltransferase. Protein Science : a Publication of the Protein Society. 11: 974-9. PMID 11910040 DOI: 10.1110/Ps.4310102  0.341
2002 Zhu Y, Drueckhammer DG. An efficient synthesis of geminal di-sulfones Tetrahedron Letters. 43: 1377-1379. DOI: 10.1016/S0040-4039(02)00023-0  0.483
2001 Yang W, Drueckhammer DG. Understanding the relative acyl-transfer reactivity of oxoesters and thioesters: computational analysis of transition state delocalization effects. Journal of the American Chemical Society. 123: 11004-9. PMID 11686705 DOI: 10.1021/Ja010726A  0.31
2000 Mishra PK, Drueckhammer DG. Coenzyme A Analogues and Derivatives: Synthesis and Applications as Mechanistic Probes of Coenzyme A Ester-Utilizing Enzymes. Chemical Reviews. 100: 3283-3310. PMID 11777425 DOI: 10.1021/Cr990010M  0.409
2000 Yang W, Drueckhammer DG. Computational studies of the aminolysis of oxoesters and thioesters in aqueous solution Organic Letters. 2: 4133-6. PMID 11150182 DOI: 10.1021/Ol006691L  0.313
2000 Vogel KW, Stark LM, Mishra PK, Yang W, Drueckhammer DG. Investigating the role of the geminal dimethyl groups of coenzyme A: synthesis and studies of a didemethyl analogue. Bioorganic & Medicinal Chemistry. 8: 2451-60. PMID 11058040 DOI: 10.1016/S0968-0896(00)00189-9  0.373
2000 Mishra PK, Drueckhammer DG. ChemInform Abstract: Coenzyme A Analogues and Derivatives: Synthesis and Applications as Mechanistic Probes of Coenzyme A Ester-Utilizing Enzymes Cheminform. 31: no-no. DOI: 10.1002/chin.200051278  0.312
1999 Bibart RT, Vogel KW, Drueckhammer DG. Development of a Second Generation Coenzyme A Analogue Synthon. The Journal of Organic Chemistry. 64: 2903-2909. PMID 11674364 DOI: 10.1021/Jo981758S  0.42
1998 Mishra PK, Drueckhammer DG. Novel cofactor derivatives and cofactor-based models. Current Opinion in Chemical Biology. 2: 758-65. PMID 9914186 DOI: 10.1016/S1367-5931(98)80114-2  0.387
1998 Vogel KW, Drueckhammer DG. A reversed thioester analogue of acetyl-coenzyme A: An inhibitor of thiolase and a synthon for other acyl-CoA analogues Journal of the American Chemical Society. 120: 3275-3283. DOI: 10.1021/Ja971758U  0.327
1997 Kurz LC, Roble JH, Nakra T, Drysdale GR, Buzan JM, Schwartz B, Drueckhammer DG. Ability of single-site mutants of citrate synthase to catalyze proton transfer from the methyl group of dethiaacetyl-coenzyme A, a non-thioester substrate analog. Biochemistry. 36: 3981-90. PMID 9092828 DOI: 10.1021/Bi963058S  0.329
1996 Duncan R, Drueckhammer DG. Preparation of Deoxy Sugars via Aldolase-Catalyzed Synthesis of 1-Deoxy-1-thioketoses. The Journal of Organic Chemistry. 61: 438-439. PMID 11666955 DOI: 10.1021/Jo9520093  0.385
1996 Schwartz B, Vogel KW, Drueckhammer DG. Coenzyme A hemithioacetals as easily prepared inhibitors of CoA ester-utilizing enzymes Journal of Organic Chemistry. 61: 9356-9361. DOI: 10.1021/Jo9616724  0.389
1995 Duncan R, Drueckhammer DG. A pseudoisomerization route to aldose sugars using aldolase catalysis Journal of Organic Chemistry. 60: 7394-7395. DOI: 10.1021/Jo00128A008  0.32
1995 Tan DS, Günter MM, Drueckhammer DG. Enzymatic resolution coupled with substrate racemization using a thioester substrate Journal of the American Chemical Society. 117: 9093-9094. DOI: 10.1021/Ja00140A037  0.481
1994 Darrow JW, Drueckhammer DG. Cyclic phosphonate analogs of hexopyranoses Journal of Organic Chemistry. 59: 2976-2985. DOI: 10.1021/Jo00090A014  0.342
1994 Martin DP, Bibart RT, Drueckhammer DG. Synthesis of novel analogs of acetyl coenzyme A: Mimics of enzyme reaction intermediates Journal of the American Chemical Society. 116: 4660-4668. DOI: 10.1021/ja00090a014  0.324
1991 Drueckhammer DG, Hennen WJ, Pederson RL, Barbas CF, Gautheron CM, Krach T, Wong CH. Enzyme catalysis in synthetic carbohydrate chemistry Synthesis. 499-525. DOI: 10.1055/S-1991-26506  0.529
1990 WONG C, DRUECKHAMMER DG, DURRWACHTER JR, LACHER B, CHAUVET CJ, WANG Y, SWEERS HM, SMITH GL, YANG LJ, HENNEN WJ. ChemInform Abstract: Enzyme-Catalyzed Synthesis of Carbohydrates Cheminform. 21. DOI: 10.1002/chin.199033344  0.464
1989 Drueckhammer DG, Durrwachter JR, Pederson RL, Crans DC, Daniels L, Wong CH. Reversible and in situ formation of organic arsenates and vanadates as organic phosphate mimics in enzymatic reactions: Mechanistic investigation of aldol reactions and synthetic applications Journal of Organic Chemistry. 54: 70-77. DOI: 10.1021/Jo00262A021  0.422
1987 Drueckhammer DG, Sadozai SK, Wong CH, Roberts SM. Biphasic one-pot synthesis of two useful and separable compounds using nicotinamide cofactor-requiring enzymes: Syntheses of (S)-4-hydroxyhexanoate and its lactone Enzyme and Microbial Technology. 9: 564-570. DOI: 10.1016/0141-0229(87)90089-5  0.423
1986 Durrwachter JR, Drueckhammer DG, Nozaki K, Sweers HM, Wong CH. Enzymic aldol condensation/isomerization as a route to unusual sugar derivatives. Journal of the American Chemical Society. 108: 7812-8. PMID 22283291 DOI: 10.1021/Ja00284A053  0.443
1985 Wong CH, Drueckhammer DG. Enzymatic synthesis of chiral hydroxy compounds using immobilized glucose dehydrogenase from Bacillus cereus for NAD(P)H regeneration Bio/Technology. 3: 649-651. DOI: 10.1038/Nbt0785-649  0.435
1985 Drueckhammer DG, Wong CH. Chemoenzymatic syntheses of fluoro sugar phosphates and analogues Journal of Organic Chemistry. 50: 5912-5913. DOI: 10.1021/Jo00350A109  0.365
1985 Drueckhammer DG, Riddle VW, Wong CH. FMN reductase catalyzed regeneration of NAD(P) for use in enzymatic synthesis Journal of Organic Chemistry. 50: 5387-5389. DOI: 10.1021/Jo00225A080  0.338
1985 Wong C, Drueckhammer DG, Sweers HM. Enzymatic vs. fermentative synthesis: thermostable glucose dehydrogenase catalyzed regeneration of NAD(P)H for use in enzymatic synthesis Journal of the American Chemical Society. 107: 4028-4031. DOI: 10.1021/Ja00299A044  0.389
Low-probability matches (unlikely to be authored by this person)
2001 Mishra P, Park PK, Drueckhammer DG. Identification of yacE (coaE) as the structural gene for dephosphocoenzyme A kinase in Escherichia coli K-12. Journal of Bacteriology. 183: 2774-8. PMID 11292795 DOI: 10.1128/Jb.183.9.2774-2778.2001  0.297
2010 DRUECKHAMMER DG, HENNEN WJ, PEDERSON RL, BARBAS CFI, GAUTHERON CM, KRACH T, WONG C. ChemInform Abstract: Enzyme Catalysis in Synthetic Carbohydrate Chemistry Cheminform. 22: no-no. DOI: 10.1002/chin.199149341  0.294
1985 WONG C, DRUECKHAMMER DG, SWEERS HM. ChemInform Abstract: ENZYMIC VS. FERMENTATIVE SYNTHESIS: THERMOSTABLE GLUCOSE DEHYDROGENASE CATALYZED REGENERATION OF NAD(P)H FOR USE IN ENZYMIC SYNTHESIS Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198543149  0.284
1988 Drueckhammer DG, Barbas CF, Nozaki K, Wong CH, Wood CY, Ciufolini MA. Chemoenzymic synthesis of chiral furan derivatives: Useful building blocks for optically active structures Journal of Organic Chemistry. 53: 1607-1611. DOI: 10.1021/Jo00243A003  0.28
1993 Martin DP, Drueckhammer DG. Separate enzymes catalyze the final two steps of coenzyme A biosynthesis in Brevibacterium ammoniagenes: purification of pantetheine phosphate adenylyltransferase. Biochemical and Biophysical Research Communications. 192: 1155-61. PMID 8389542 DOI: 10.1006/bbrc.1993.1537  0.276
2007 Ballou LM, Selinger ES, Choi JY, Drueckhammer DG, Lin RZ. Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one. The Journal of Biological Chemistry. 282: 24463-70. PMID 17562705 DOI: 10.1074/Jbc.M704741200  0.274
1994 Usher KC, Remington SJ, Martin DP, Drueckhammer DG. A very short hydrogen bond provides only moderate stabilization of an enzyme-inhibitor complex of citrate synthase. Biochemistry. 33: 7753-9. PMID 8011640 DOI: 10.1021/bi00191a002  0.273
2010 DUNCAN R, DRUECKHAMMER DG. ChemInform Abstract: Preparation of Deoxy Sugars via Aldolase-Catalyzed Synthesis of 1- Deoxy-1-thioketoses. Cheminform. 27: no-no. DOI: 10.1002/chin.199623252  0.272
2013 Drueckhammer DG, Gao SQ, Liang X, Liao J. Acetone-heptane as a solvent system for combining chromatography on silica gel with solvent recycling Acs Sustainable Chemistry and Engineering. 1: 87-90. DOI: 10.1021/Sc300044C  0.269
2001 Yang W, He H, Drueckhammer DG. Computer-Guided Design in Molecular Recognition: Design and Synthesis of a Glucopyranose Receptor Angewandte Chemie. 113: 1764-1768. DOI: 10.1002/1521-3757(20010504)113:9<1764::Aid-Ange17640>3.0.Co;2-Y  0.268
1992 MARTIN DP, DRUECKHAMMER DG. ChemInform Abstract: Combined Chemical and Enzymatic Synthesis of Coenzyme A Analogues. Cheminform. 23: no-no. DOI: 10.1002/chin.199251299  0.254
1996 Darrow JW, Drueckhammer DG. A cyclic phosphonamidate analogue of glucose as a selective inhibitor of inverting glycosidases. Bioorganic & Medicinal Chemistry. 4: 1341-8. PMID 8879556 DOI: 10.1016/0968-0896(96)00121-6  0.247
1992 Martin DP, Drueckhammer DG. Combined chemical and enzymatic synthesis of coenzyme A analogs Journal of the American Chemical Society. 114: 7287-7288. DOI: 10.1021/ja00044a045  0.244
1986 DRUECKHAMMER DG, WONG C. ChemInform Abstract: Chemoenzymatic Syntheses of Fluoro Sugar Phosphates and Analogues. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198631319  0.243
1999 Gu Z, Drueckhammer DG, Kurz L, Liu K, Martin DP, McDermott A. Solid state NMR studies of hydrogen bonding in a citrate synthase inhibitor complex. Biochemistry. 38: 8022-31. PMID 10387046 DOI: 10.1021/Bi9813680  0.241
1996 Schwartz B, Drueckhammer DG. A stereochemical probe of the tetrahedral intermediate in the reactions of acetyl-coenzyme A dependent acetyltransferases Journal of the American Chemical Society. 118: 9826-9830. DOI: 10.1021/Ja9616241  0.23
1986 Durrwachter JR, Drueckhammer DG, Nozaki K, Marcel Sweers H, Wong CH. Enzymatic aldol condensation/isomerization as a route to unusual sugar derivatives Journal of the American Chemical Society. 108: 7812-7818.  0.229
1986 DRUECKHAMMER DG, RIDDLE VW, WONG C. ChemInform Abstract: FMN Reductase Catalyzed Regeneration of NAD(P) for Use in Enzymatic Synthesis. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198622346  0.229
1987 DURRWACHTER JR, DRUECKHAMMER DG, NOZAKI K, SWEERS HM, WONG C. ChemInform Abstract: Enzymatic Aldol Condensation/Isomerization as a Route to Unusual Sugar Derivatives. Cheminform. 18. DOI: 10.1002/chin.198715352  0.226
1997 Gehring AM, Lambalot RH, Vogel KW, Drueckhammer DG, Walsh CT. Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase. Chemistry & Biology. 4: 17-24. PMID 9070424 DOI: 10.1016/S1074-5521(97)90233-7  0.219
1999 Conn MM, Kappock J, Drueckhammer D, Cammack R, Hall D, Cass T, Stewart JD, Cousins GR, Sanders JK, Flitsch S, Lowden PA, Newman R. Chemical biology Current Opinion in Chemical Biology. 3: 631-638. DOI: 10.1016/S1367-5931(99)00038-1  0.212
1995 Schwartz B, Drueckhammer DG. A simple method for determining the relative strengths of normal and low-barrier hydrogen bonds in solution: Implications to enzyme catalysis Journal of the American Chemical Society. 117: 11902-11905. DOI: 10.1021/Ja00153A011  0.205
2010 SCHWARTZ B, DRUECKHAMMER DG. ChemInform Abstract: A Stereochemical Probe of the Tetrahedral Intermediate in the Reactions of Acetyl-Coenzyme A Dependent Acetyltransferases. Cheminform. 28: no-no. DOI: 10.1002/chin.199707256  0.202
1995 Schwartz B, Drueckhammer DG, Usher KC, Remington SJ. alpha-Fluoro acid and alpha-fluoro amide analogs of acetyl-CoA as inhibitors of citrate synthase: effect of pKa matching on binding affinity and hydrogen bond length. Biochemistry. 34: 15459-66. PMID 7492547 DOI: 10.1021/bi00047a010  0.198
1993 Grimes MT, Drueckhammer DG. Membrane-enclosed electroenzymatic catalysis with a low molecular weight electron-transfer mediator Journal of Organic Chemistry. 58: 6148-6150. DOI: 10.1021/Jo00074A056  0.195
2010 DUNCAN R, DRUECKHAMMER DG. ChemInform Abstract: A Pseudoisomerization Route to Aldose Sugars Using Aldolase Catalysis. Cheminform. 27: no-no. DOI: 10.1002/chin.199614234  0.195
2010 DARROW JW, DRUECKHAMMER DG. ChemInform Abstract: Cyclic Phosphonate Analogues of Hexopyranoses. Cheminform. 25: no-no. DOI: 10.1002/chin.199450229  0.189
1993 Duncan R, Drueckhammer DG. Phosphorothioate and phosphoramide analogs of dihydroxyacetone phosphate Tetrahedron Letters. 34: 1733-1736. DOI: 10.1016/S0040-4039(00)60764-5  0.187
1991 Rusnak F, Sakaitani M, Drueckhammer D, Reichert J, Walsh CT. Biosynthesis of the Escherichia coli siderophore enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent phosphopantetheine. Biochemistry. 30: 2916-27. PMID 1826089 DOI: 10.1021/Bi00225A027  0.185
2010 DUNCAN R, DRUECKHAMMER DG. ChemInform Abstract: Phosphorothioate and Phosphoramide Analogs of Dihydroxyacetone Phosphate. Cheminform. 24: no-no. DOI: 10.1002/chin.199330215  0.183
1988 DRUECKHAMMER DG, BARBAS CFI, NOZAKI K, WONG C, WOOD CY, CIUFOLINI MA. ChemInform Abstract: Chemoenzymic Synthesis of Chiral Furan Derivatives: Useful Building Blocks for Optically Active Structures. Cheminform. 19. DOI: 10.1002/chin.198840298  0.158
2001 Yang W, He H, Drueckhammer DG. Computer-Guided Design in Molecular Recognition: Design and Synthesis of a Glucopyranose Receptor This work was supported by the National Institutes of Health (grant DK5523402). Angewandte Chemie (International Ed. in English). 40: 1714-1718. PMID 11353489 DOI: 10.1002/1521-3773(20010504)40:9<1714::AID-ANIE17140>3.0.CO;2-F  0.115
2001 Yang W, Drueckhammer DG. ChemInform Abstract: Computational Studies of the Aminolysis of Oxoesters and Thioesters in Aqueous Solution Cheminform. 32: no-no. DOI: 10.1002/chin.200110025  0.053
1998 Um PJ, Drueckhammer DG. Dynamic enzymatic resolution of thioesters Journal of the American Chemical Society. 120: 5605-5610. DOI: 10.1021/ja980445b  0.053
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