| Year |
Citation |
Score |
| 2024 |
Holtzman MJ, Zhang Y, Wu K, Romero AG. Mitogen-activated protein kinase-guided drug discovery for post-viral and related types of lung disease. European Respiratory Review : An Official Journal of the European Respiratory Society. 33. PMID 38417971 DOI: 10.1183/16000617.0220-2023 |
0.327 |
|
| 2023 |
Wu K, Zhang Y, Austin SR, Declue HY, Byers DE, Crouch EC, Holtzman MJ. Lung remodeling regions in long-term Covid-19 feature basal epithelial cell reprogramming. The American Journal of Pathology. PMID 36868468 DOI: 10.1016/j.ajpath.2023.02.005 |
0.323 |
|
| 2022 |
Wu K, Zhang Y, Austin SR, Declue HY, Byers DE, Crouch EC, Holtzman MJ. Lung remodeling regions in long-term Covid-19 feature basal epithelial cell reprogramming. Medrxiv : the Preprint Server For Health Sciences. PMID 36172126 DOI: 10.1101/2022.09.17.22280043 |
0.308 |
|
| 2022 |
Hazan G, Eubanks A, Gierasch C, Atkinson J, Fox C, Hernandez-Leyva A, Rosen AL, Kau AL, Agapov E, Alexander-Brett J, Steinberg D, Kelley D, White M, Byers D, Wu K, ... ... Holtzman MJ, et al. Age-Dependent Reduction in Asthmatic Pathology through Reprogramming of Postviral Inflammatory Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 35173037 DOI: 10.4049/jimmunol.2101094 |
0.35 |
|
| 2021 |
Wu K, Kamimoto K, Zhang Y, Yang K, Keeler SP, Gerovac BJ, Agapov EV, Austin SP, Yantis J, Gissy KA, Byers DE, Alexander-Brett J, Hoffmann CM, Wallace M, Hughes ME, ... ... Holtzman MJ, et al. Basal-epithelial stem cells cross an alarmin checkpoint for post-viral lung disease. The Journal of Clinical Investigation. PMID 34343135 DOI: 10.1172/JCI149336 |
0.334 |
|
| 2021 |
Wang X, Wu K, Keeler SP, Mao D, Agapov EV, Zhang Y, Holtzman MJ. TLR3-Activated Monocyte-Derived Dendritic Cells Trigger Progression from Acute Viral Infection to Chronic Disease in the Lung. Journal of Immunology (Baltimore, Md. : 1950). PMID 33514511 DOI: 10.4049/jimmunol.2000965 |
0.427 |
|
| 2021 |
Katz-Kiriakos E, Steinberg DF, Kluender CE, Osorio OA, Newsom-Stewart C, Baronia A, Byers DE, Holtzman MJ, Katafiasz D, Bailey KL, Brody SL, Miller MJ, Alexander-Brett J. Epithelial IL-33 appropriates exosome trafficking for secretion in chronic airway disease. Jci Insight. PMID 33507882 DOI: 10.1172/jci.insight.136166 |
0.302 |
|
| 2020 |
Chen R, Wang L, Koch T, Curtis V, Yin-DeClue H, Handley SA, Shan L, Holtzman MJ, Castro M, Wang L. Gender effects in the association between airway microbiome and asthma. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. PMID 32931909 DOI: 10.1016/J.Anai.2020.09.007 |
0.339 |
|
| 2020 |
Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, ... ... Holtzman MJ, et al. A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2. Cell. PMID 32931734 DOI: 10.1016/J.Cell.2020.08.026 |
0.394 |
|
| 2020 |
Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, ... Holtzman MJ, et al. Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function. Nature Immunology. PMID 32879513 DOI: 10.1038/S41590-020-0794-2 |
0.36 |
|
| 2020 |
Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, ... Holtzman MJ, et al. SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function. Nature Immunology. PMID 32839612 DOI: 10.1038/S41590-020-0778-2 |
0.44 |
|
| 2020 |
Case JB, Rothlauf PW, Chen RE, Kafai NM, Fox JM, Smith BK, Shrihari S, McCune BT, Harvey IB, Keeler SP, Bloyet LM, Zhao H, Ma M, Adams LJ, Winkler ES, ... Holtzman MJ, et al. Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice. Cell Host & Microbe. PMID 32798445 DOI: 10.1016/J.Chom.2020.07.018 |
0.392 |
|
| 2020 |
Winkler ES, Bailey AL, Kafai NM, Nair S, McCune BT, Yu J, Fox JM, Chen RE, Earnest JT, Keeler SP, Ritter JH, Kang LI, Dort S, Robichaud A, Head R, ... Holtzman MJ, et al. SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function. Biorxiv : the Preprint Server For Biology. PMID 32676600 DOI: 10.1101/2020.07.09.196188 |
0.373 |
|
| 2020 |
Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, ... ... Holtzman MJ, et al. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. PMID 32668443 DOI: 10.1038/S41586-020-2548-6 |
0.331 |
|
| 2020 |
Wu K, Wang X, Keeler SP, Gerovac BJ, Agapov EV, Byers DE, Gilfillan S, Colonna M, Zhang Y, Holtzman MJ. Group 2 Innate Lymphoid Cells Must Partner with the Myeloid-Macrophage Lineage for Long-Term Postviral Lung Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 32641386 DOI: 10.4049/Jimmunol.2000181 |
0.516 |
|
| 2020 |
Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, ... ... Holtzman MJ, et al. A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies. Cell. PMID 32553273 DOI: 10.1016/J.Cell.2020.06.011 |
0.385 |
|
| 2019 |
Sodhi CP, Nguyen J, Yamaguchi Y, Werts AD, Lu P, Ladd MR, Fulton WB, Kovler ML, Wang S, Prindle T, Zhang Y, Lazartigues ED, Holtzman MJ, Alcorn JF, Hackam DJ, et al. A Dynamic Variation of Pulmonary ACE2 Is Required To Modulate Neutrophilic Inflammation in Response to Lung Infection in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 31645418 DOI: 10.4049/Jimmunol.1900579 |
0.425 |
|
| 2019 |
Zhang Y, Mao D, Keeler SP, Wang X, Wu K, Gerovac BJ, Shornick LL, Agapov EV, Holtzman MJ. Respiratory Enterovirus (Like Parainfluenza Virus) Can Cause Chronic Lung Disease If Protection by Airway Epithelial STAT1 Is Lost. Journal of Immunology (Baltimore, Md. : 1950). PMID 30804041 DOI: 10.4049/Jimmunol.1801491 |
0.486 |
|
| 2018 |
Keeler SP, Gerovac BJ, Wu K, Wang X, Chartock JR, Byers DE, Romero AG, Holtzman MJ. Epithelial-Immune Cell Interactions for Drug Discovery in Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society. 15: S260-S265. PMID 30759005 DOI: 10.1513/Annalsats.201808-531Mg |
0.482 |
|
| 2018 |
Keeler SP, Agapov EV, Hinojosa ME, Letvin AN, Wu K, Holtzman MJ. Influenza A Virus Infection Causes Chronic Lung Disease Linked to Sites of Active Viral RNA Remnants. Journal of Immunology (Baltimore, Md. : 1950). PMID 30209189 DOI: 10.4049/Jimmunol.1800671 |
0.743 |
|
| 2017 |
Siller SS, Sharma H, Li S, Yang J, Zhang Y, Holtzman MJ, Winuthayanon W, Colognato H, Holdener BC, Li FQ, Takemaru KI. Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation. Plos Genetics. 13: e1007128. PMID 29244804 DOI: 10.1371/Journal.Pgen.1007128 |
0.319 |
|
| 2017 |
Byers DE, Wu K, Dang-Vu G, Jin X, Agapov E, Zhang X, Battaile JT, Schechtman K, Yusen R, Pierce RA, Holtzman MJ. Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) expression tracks with M2-like macrophage activity and disease severity in COPD. Chest. PMID 29017955 DOI: 10.1016/J.Chest.2017.09.044 |
0.407 |
|
| 2017 |
Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS. The microbial metabolite desaminotyrosine protects from influenza through type I interferon. Science (New York, N.Y.). 357: 498-502. PMID 28774928 DOI: 10.1126/Science.Aam5336 |
0.401 |
|
| 2017 |
Chatterjee S, Luthra P, Esaulova E, Agapov E, Yen BC, Borek DM, Edwards MR, Mittal A, Jordan DS, Ramanan P, Moore ML, Pappu RV, Holtzman MJ, Artyomov MN, Basler CF, et al. Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses. Nature Microbiology. 2: 17101. PMID 28665409 DOI: 10.1038/Nmicrobiol.2017.101 |
0.417 |
|
| 2017 |
Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, et al. ATS-NHLBI Asthma COPD Overlap (ACO) Workshop Report. American Journal of Respiratory and Critical Care Medicine. PMID 28636425 DOI: 10.1164/Rccm.201705-0973Ws |
0.377 |
|
| 2017 |
Ehlers A, Xie W, Agapov E, Brown S, Steinberg D, Tidwell R, Sajol G, Schutz R, Weaver R, Yu H, Castro M, Bacharier LB, Wang X, Holtzman MJ, Haspel JA. BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes. Mucosal Immunology. PMID 28401936 DOI: 10.1038/Mi.2017.24 |
0.446 |
|
| 2017 |
Liu Y, Gunsten SP, Sultan DH, Luehmann HP, Zhao Y, Blackwell TS, Bollermann-Nowlis Z, Pan JH, Byers DE, Atkinson JJ, Kreisel D, Holtzman MJ, Gropler RJ, Combadiere C, Brody SL. PET-based Imaging of Chemokine Receptor 2 in Experimental and Disease-related Lung Inflammation. Radiology. 161409. PMID 28045644 DOI: 10.1148/Radiol.2016161409 |
0.338 |
|
| 2016 |
Olias P, Etheridge RD, Zhang Y, Holtzman MJ, Sibley LD. Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression. Cell Host & Microbe. 20: 72-82. PMID 27414498 DOI: 10.1016/J.Chom.2016.06.006 |
0.343 |
|
| 2016 |
Lu Q, Yokoyama CC, Williams JW, Baldridge MT, Jin X, DesRochers B, Bricker T, Wilen CB, Bagaitkar J, Loginicheva E, Sergushichev A, Kreamalmeyer D, Keller BC, Zhao Y, Kambal A, ... ... Holtzman MJ, et al. Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis. Cell Host & Microbe. 19: 102-113. PMID 26764600 DOI: 10.1016/J.Chom.2015.12.011 |
0.427 |
|
| 2015 |
Chen J, Zhao J, Chen L, Dong N, Ying Z, Cai Z, Ji D, Zhang Y, Dong L, Li Y, Jiang L, Holtzman MJ, Chen C. STAT1 modification improves therapeutic effects of interferons on lung cancer cells. Journal of Translational Medicine. 13: 293. PMID 26351076 DOI: 10.1186/S12967-015-0656-0 |
0.351 |
|
| 2015 |
Dickinson JD, Alevy Y, Malvin NP, Patel KK, Gunsten SP, Holtzman MJ, Stappenbeck TS, Brody SL. IL13 activates autophagy to regulate secretion in airway epithelial cells. Autophagy. 0. PMID 26062017 DOI: 10.1080/15548627.2015.1056967 |
0.46 |
|
| 2015 |
Wu K, Byers DE, Jin X, Agapov E, Alexander-Brett J, Patel AC, Cella M, Gilfilan S, Colonna M, Kober DL, Brett TJ, Holtzman MJ. TREM-2 promotes macrophage survival and lung disease after respiratory viral infection. The Journal of Experimental Medicine. 212: 681-97. PMID 25897174 DOI: 10.1084/Jem.20141732 |
0.408 |
|
| 2015 |
Kim HJ, Kim CH, Kim MJ, Ryu JH, Seong SY, Kim S, Lim SJ, Holtzman MJ, Yoon JH. Duox2-derived Reactive Oxygen Species Induce Pattern Recognition Receptors' Expression Against Influenza A Virus in Nasal Mucosa. American Journal of Respiratory Cell and Molecular Biology. PMID 25751630 DOI: 10.1165/Rcmb.2014-0334Oc |
0.41 |
|
| 2015 |
Gowdy KM, Martinu T, Nugent JL, Manzo ND, Zhang HL, Kelly FL, Holtzman MJ, Palmer SM. Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection. Transplant Immunology. 32: 51-60. PMID 25446809 DOI: 10.1016/J.Trim.2014.10.005 |
0.367 |
|
| 2015 |
Morales DJ, Monte K, Sun L, Struckhoff JJ, Agapov E, Holtzman MJ, Stappenbeck TS, Lenschow DJ. Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice. Journal of Virology. 89: 337-49. PMID 25320315 DOI: 10.1128/Jvi.02110-14 |
0.385 |
|
| 2015 |
Alexander-Brett J, Holtzman MJ. Virus Infection of Airway Epithelial Cells Mucosal Immunology: Fourth Edition. 1: 1013-1021. DOI: 10.1016/B978-0-12-415847-4.00053-7 |
0.443 |
|
| 2014 |
Holtzman MJ, Byers DE, Brett JA, Patel AC, Agapov E, Jin X, Wu K. Linking acute infection to chronic lung disease. The role of IL-33-expressing epithelial progenitor cells. Annals of the American Thoracic Society. 11: S287-91. PMID 25525734 DOI: 10.1513/Annalsats.201402-056Aw |
0.464 |
|
| 2014 |
Holtzman MJ, Byers DE, Alexander-Brett J, Wang X. The role of airway epithelial cells and innate immune cells in chronic respiratory disease. Nature Reviews. Immunology. 14: 686-98. PMID 25234144 DOI: 10.1038/Nri3739 |
0.375 |
|
| 2014 |
Patel DA, You Y, Huang G, Byers DE, Kim HJ, Agapov E, Moore ML, Peebles RS, Castro M, Sumino K, Shifren A, Brody SL, Holtzman MJ. Interferon response and respiratory virus control are preserved in bronchial epithelial cells in asthma. The Journal of Allergy and Clinical Immunology. 134: 1402-1412.e7. PMID 25216987 DOI: 10.1016/J.Jaci.2014.07.013 |
0.454 |
|
| 2014 |
Pan JH, Adair-Kirk TL, Patel AC, Huang T, Yozamp NS, Xu J, Reddy EP, Byers DE, Pierce RA, Holtzman MJ, Brody SL. Myb permits multilineage airway epithelial cell differentiation. Stem Cells (Dayton, Ohio). 32: 3245-56. PMID 25103188 DOI: 10.1002/Stem.1814 |
0.379 |
|
| 2014 |
Philippot Q, Deslée G, Adair-Kirk TL, Woods JC, Byers D, Conradi S, Dury S, Perotin JM, Lebargy F, Cassan C, Le Naour R, Holtzman MJ, Pierce RA. Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary disease. Plos One. 9: e96285. PMID 24789352 DOI: 10.1371/Journal.Pone.0096285 |
0.304 |
|
| 2014 |
Kober DL, Wanhainen KM, Johnson BM, Randolph DT, Holtzman MJ, Brett TJ. Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases. Protein Expression and Purification. 96: 32-8. PMID 24508568 DOI: 10.1016/J.Pep.2014.01.015 |
0.326 |
|
| 2014 |
Gu X, Karp PH, Brody SL, Pierce RA, Welsh MJ, Holtzman MJ, Ben-Shahar Y. Chemosensory functions for pulmonary neuroendocrine cells. American Journal of Respiratory Cell and Molecular Biology. 50: 637-46. PMID 24134460 DOI: 10.1165/Rcmb.2013-0199Oc |
0.389 |
|
| 2013 |
Byers DE, Alexander-Brett J, Patel AC, Agapov E, Dang-Vu G, Jin X, Wu K, You Y, Alevy Y, Girard JP, Stappenbeck TS, Patterson GA, Pierce RA, Brody SL, Holtzman MJ. Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease. The Journal of Clinical Investigation. 123: 3967-82. PMID 23945235 DOI: 10.1172/Jci65570 |
0.337 |
|
| 2013 |
Kim HJ, Kim CH, Ryu JH, Kim MJ, Park CY, Lee JM, Holtzman MJ, Yoon JH. Reactive oxygen species induce antiviral innate immune response through IFN-λ regulation in human nasal epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 49: 855-65. PMID 23786562 DOI: 10.1165/Rcmb.2013-0003Oc |
0.428 |
|
| 2012 |
Alevy YG, Patel AC, Romero AG, Patel DA, Tucker J, Roswit WT, Miller CA, Heier RF, Byers DE, Brett TJ, Holtzman MJ. IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. The Journal of Clinical Investigation. 122: 4555-68. PMID 23187130 DOI: 10.1172/Jci64896 |
0.306 |
|
| 2012 |
Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, Holtzman MJ, Brett TJ. Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation. The Journal of Biological Chemistry. 287: 42138-49. PMID 23112050 DOI: 10.1074/Jbc.M112.410282 |
0.314 |
|
| 2012 |
Page C, Goicochea L, Matthews K, Zhang Y, Klover P, Holtzman MJ, Hennighausen L, Frieman M. Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection. Journal of Virology. 86: 13334-49. PMID 23015710 DOI: 10.1128/Jvi.01689-12 |
0.458 |
|
| 2012 |
Holtzman MJ. Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens. The Journal of Clinical Investigation. 122: 2741-8. PMID 22850884 DOI: 10.1172/Jci60325 |
0.489 |
|
| 2012 |
Patel DA, Patel AC, Nolan WC, Zhang Y, Holtzman MJ. High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery. Plos One. 7: e36594. PMID 22574190 DOI: 10.1371/Journal.Pone.0036594 |
0.35 |
|
| 2012 |
Sumino K, Tucker J, Shahab M, Jaffee KF, Visness CM, Gern JE, Bloomberg GR, Holtzman MJ. Antiviral IFN-γ responses of monocytes at birth predict respiratory tract illness in the first year of life. The Journal of Allergy and Clinical Immunology. 129: 1267-1273.e1. PMID 22460071 DOI: 10.1016/J.Jaci.2012.02.033 |
0.412 |
|
| 2012 |
Wang W, Nguyen NM, Agapov E, Holtzman MJ, Woods JC. Monitoring in vivo changes in lung microstructure with ³He MRI in Sendai virus-infected mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 112: 1593-9. PMID 22383505 DOI: 10.1152/Japplphysiol.01165.2011 |
0.403 |
|
| 2011 |
Byers DE, Holtzman MJ. Alternatively activated macrophages and airway disease. Chest. 140: 768-74. PMID 21896520 DOI: 10.1378/Chest.10-2132 |
0.494 |
|
| 2011 |
Holtzman MJ, Patel DA, Zhang Y, Patel AC. Host epithelial-viral interactions as cause and cure for asthma. Current Opinion in Immunology. 23: 487-94. PMID 21703838 DOI: 10.1016/J.Coi.2011.05.010 |
0.5 |
|
| 2011 |
Holtzman M, Patel D, Kim HJ, Kim H, You Y, Zhang Y. Hypersusceptibility to respiratory viruses as a shared mechanism for asthma, chronic obstructive pulmonary disease, and cystic fibrosis. American Journal of Respiratory Cell and Molecular Biology. 44: 739-42. PMID 21653905 DOI: 10.1165/Rcmb.2011-0120Ed |
0.392 |
|
| 2011 |
Le Cras TD, Acciani TH, Mushaben EM, Kramer EL, Pastura PA, Hardie WD, Korfhagen TR, Sivaprasad U, Ericksen M, Gibson AM, Holtzman MJ, Whitsett JA, Hershey GK. Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L414-21. PMID 21224214 DOI: 10.1152/Ajplung.00346.2010 |
0.374 |
|
| 2010 |
Zhang Y, Hinojosa ME, Yoo N, Holtzman MJ. Viral and host strategies to take advantage of the innate immune response. American Journal of Respiratory Cell and Molecular Biology. 43: 507-10. PMID 20971885 DOI: 10.1165/Rcmb.2009-0213Ed |
0.721 |
|
| 2010 |
Cheung DS, Ehlenbach SJ, Kitchens RT, Riley DA, Thomas LL, Holtzman MJ, Grayson MH. Cutting edge: CD49d+ neutrophils induce FcepsilonRI expression on lung dendritic cells in a mouse model of postviral asthma. Journal of Immunology (Baltimore, Md. : 1950). 185: 4983-7. PMID 20876348 DOI: 10.4049/Jimmunol.1002456 |
0.459 |
|
| 2010 |
Sumino KC, Walter MJ, Mikols CL, Thompson SA, Gaudreault-Keener M, Arens MQ, Agapov E, Hormozdi D, Gaynor AM, Holtzman MJ, Storch GA. Detection of respiratory viruses and the associated chemokine responses in serious acute respiratory illness. Thorax. 65: 639-44. PMID 20627924 DOI: 10.1136/Thx.2009.132480 |
0.342 |
|
| 2010 |
Byers DE, Holtzman MJ. Alternatively activated macrophages as cause or effect in airway disease. American Journal of Respiratory Cell and Molecular Biology. 43: 1-4. PMID 20587775 DOI: 10.1165/Rcmb.2009-0407Ed |
0.374 |
|
| 2010 |
Benoit LA, Holtzman MJ. New immune pathways from chronic post-viral lung disease. Annals of the New York Academy of Sciences. 1183: 195-210. PMID 20146716 DOI: 10.1111/J.1749-6632.2009.05136.X |
0.482 |
|
| 2010 |
Gitlin L, Benoit L, Song C, Cella M, Gilfillan S, Holtzman MJ, Colonna M. Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. Plos Pathogens. 6: e1000734. PMID 20107606 DOI: 10.1371/Journal.Ppat.1000734 |
0.443 |
|
| 2010 |
Wu X, Micka WS, Mao D, Kolar G, Zhang Y, Holtzman MJ, Atkinson JP. Complement deficiency leads to a prominent lymphoid nodule development in a Sendai virus-induced mouse model of asthma Molecular Immunology. 47: 2273-2273. DOI: 10.1016/J.Molimm.2010.05.223 |
0.38 |
|
| 2009 |
Tachdjian R, Mathias C, Al Khatib S, Bryce PJ, Kim HS, Blaeser F, O'Connor BD, Rzymkiewicz D, Chen A, Holtzman MJ, Hershey GK, Garn H, Harb H, Renz H, Oettgen HC, et al. Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. The Journal of Experimental Medicine. 206: 2191-204. PMID 19770271 DOI: 10.1084/Jem.20091480 |
0.359 |
|
| 2009 |
Agapov E, Battaile JT, Tidwell R, Hachem R, Patterson GA, Pierce RA, Atkinson JJ, Holtzman MJ. Macrophage chitinase 1 stratifies chronic obstructive lung disease. American Journal of Respiratory Cell and Molecular Biology. 41: 379-84. PMID 19491341 DOI: 10.1165/2009-0122Rc |
0.381 |
|
| 2009 |
Holtzman MJ, Byers DE, Benoit LA, Battaile JT, You Y, Agapov E, Park C, Grayson MH, Kim EY, Patel AC. Immune pathways for translating viral infection into chronic airway disease. Advances in Immunology. 102: 245-76. PMID 19477323 DOI: 10.1016/S0065-2776(09)01205-X |
0.679 |
|
| 2009 |
Deslee G, Woods JC, Moore CM, Liu L, Conradi SH, Milne M, Gierada DS, Pierce J, Patterson A, Lewit RA, Battaile JT, Holtzman MJ, Hogg JC, Pierce RA. Elastin expression in very severe human COPD. The European Respiratory Journal. 34: 324-31. PMID 19357152 DOI: 10.1183/09031936.00123008 |
0.356 |
|
| 2009 |
Patel AC, Brett TJ, Holtzman MJ. The role of CLCA proteins in inflammatory airway disease. Annual Review of Physiology. 71: 425-49. PMID 18954282 DOI: 10.1146/Annurev.Physiol.010908.163253 |
0.4 |
|
| 2008 |
Kim EY, Battaile JT, Patel AC, You Y, Agapov E, Grayson MH, Benoit LA, Byers DE, Alevy Y, Tucker J, Swanson S, Tidwell R, Tyner JW, Morton JD, Castro M, ... ... Holtzman MJ, et al. Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nature Medicine. 14: 633-40. PMID 18488036 DOI: 10.1038/Nm1770 |
0.709 |
|
| 2008 |
Fujisawa T, Ide K, Holtzman MJ, Suda T, Suzuki K, Kuroishi S, Chida K, Nakamura H. Involvement of the p38 MAPK pathway in IL-13-induced mucous cell metaplasia in mouse tracheal epithelial cells. Respirology (Carlton, Vic.). 13: 191-202. PMID 18339016 DOI: 10.1111/J.1440-1843.2008.01237.X |
0.366 |
|
| 2008 |
Akk AM, Simmons PM, Chan HW, Agapov E, Holtzman MJ, Grayson MH, Pham CT. Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection. Journal of Immunology (Baltimore, Md. : 1950). 180: 3535-42. PMID 18292580 DOI: 10.4049/Jimmunol.180.5.3535 |
0.482 |
|
| 2008 |
Shornick LP, Wells AG, Zhang Y, Patel AC, Huang G, Takami K, Sosa M, Shukla NA, Agapov E, Holtzman MJ. Airway epithelial versus immune cell Stat1 function for innate defense against respiratory viral infection. Journal of Immunology (Baltimore, Md. : 1950). 180: 3319-28. PMID 18292557 DOI: 10.4049/Jimmunol.180.5.3319 |
0.461 |
|
| 2007 |
Grayson MH, Cheung D, Rohlfing MM, Kitchens R, Spiegel DE, Tucker J, Battaile JT, Alevy Y, Yan L, Agapov E, Kim EY, Holtzman MJ. Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia. The Journal of Experimental Medicine. 204: 2759-69. PMID 17954569 DOI: 10.1084/Jem.20070360 |
0.628 |
|
| 2007 |
Grayson MH, Holtzman MJ. Emerging role of dendritic cells in respiratory viral infection. Journal of Molecular Medicine (Berlin, Germany). 85: 1057-68. PMID 17891367 DOI: 10.1007/S00109-007-0212-3 |
0.482 |
|
| 2007 |
Grayson MH, Ramos MS, Rohlfing MM, Kitchens R, Wang HD, Gould A, Agapov E, Holtzman MJ. Controls for lung dendritic cell maturation and migration during respiratory viral infection. Journal of Immunology (Baltimore, Md. : 1950). 179: 1438-48. PMID 17641009 DOI: 10.4049/Jimmunol.179.3.1438 |
0.455 |
|
| 2007 |
Stout BA, Melendez K, Seagrave J, Holtzman MJ, Wilson B, Xiang J, Tesfaigzi Y. STAT1 activation causes translocation of Bax to the endoplasmic reticulum during the resolution of airway mucous cell hyperplasia by IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 178: 8107-16. PMID 17548649 DOI: 10.4049/Jimmunol.178.12.8107 |
0.362 |
|
| 2007 |
Zhang Y, Huang G, Shornick LP, Roswit WT, Shipley JM, Brody SL, Holtzman MJ. A transgenic FOXJ1-Cre system for gene inactivation in ciliated epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 36: 515-9. PMID 17255554 DOI: 10.1165/Rcmb.2006-0475Rc |
0.376 |
|
| 2006 |
Grayson MH, Holtzman MJ. Chemokine complexity: the case for CCL5. American Journal of Respiratory Cell and Molecular Biology. 35: 143-6. PMID 16847105 DOI: 10.1165/Rcmb.F318 |
0.444 |
|
| 2006 |
Adler KB, Shapiro SD, Gallup M, Wu R, Randell SH, Holtzman MJ, Evans CM, Jacoby DB, Tesfaigzi Y, Rose MC, Mossman BT, Prince A, Reddy SP, Davis CW, Matthay MA. Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum. American Journal of Respiratory Cell and Molecular Biology. 34: 523-6. PMID 16618787 DOI: 10.1165/Rcmb.F311 |
0.344 |
|
| 2006 |
Patel AC, Morton JD, Kim EY, Alevy Y, Swanson S, Tucker J, Huang G, Agapov E, Phillips TE, Fuentes ME, Iglesias A, Aud D, Allard JD, Dabbagh K, Peltz G, ... Holtzman MJ, et al. Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members. Physiological Genomics. 25: 502-13. PMID 16569774 DOI: 10.1152/Physiolgenomics.00321.2005 |
0.596 |
|
| 2006 |
Deppong C, Juehne TI, Hurchla M, Friend LD, Shah DD, Rose CM, Bricker TL, Shornick LP, Crouch EC, Murphy TL, Holtzman MJ, Murphy KM, Green JM. Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation. Journal of Immunology (Baltimore, Md. : 1950). 176: 3909-13. PMID 16547224 DOI: 10.4049/Jimmunol.176.7.3909 |
0.34 |
|
| 2006 |
Holtzman MJ, Battaile JT, Patel AC. Immunogenetic programs for viral induction of mucous cell metaplasia. American Journal of Respiratory Cell and Molecular Biology. 35: 29-39. PMID 16543602 DOI: 10.1165/Rcmb.2006-0092Sf |
0.463 |
|
| 2006 |
Grayson MH, Holtzman MJ. Chemokine signaling regulates apoptosis as well as immune cell traffic in host defense. Cell Cycle (Georgetown, Tex.). 5: 380-3. PMID 16479157 DOI: 10.4161/Cc.5.4.2427 |
0.429 |
|
| 2006 |
Tyner JW, Kim EY, Ide K, Pelletier MR, Roswit WT, Morton JD, Battaile JT, Patel AC, Patterson GA, Castro M, Spoor MS, You Y, Brody SL, Holtzman MJ. Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals. The Journal of Clinical Investigation. 116: 309-21. PMID 16453019 DOI: 10.1172/Jci25167 |
0.648 |
|
| 2006 |
Agapov E, Sumino KC, Gaudreault-Keener M, Storch GA, Holtzman MJ. Genetic variability of human metapneumovirus infection: evidence of a shift in viral genotype without a change in illness. The Journal of Infectious Diseases. 193: 396-403. PMID 16388487 DOI: 10.1086/499310 |
0.302 |
|
| 2005 |
Tyner JW, Uchida O, Kajiwara N, Kim EY, Patel AC, O'Sullivan MP, Walter MJ, Schwendener RA, Cook DN, Danoff TM, Holtzman MJ. CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection. Nature Medicine. 11: 1180-7. PMID 16208318 DOI: 10.1038/Nm1303 |
0.671 |
|
| 2005 |
Holtzman MJ, Tyner JW, Kim EY, Lo MS, Patel AC, Shornick LP, Agapov E, Zhang Y. Acute and chronic airway responses to viral infection: implications for asthma and chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 2: 132-40. PMID 16113481 DOI: 10.1513/pats.200502-015AW |
0.79 |
|
| 2005 |
Sumino KC, Agapov E, Pierce RA, Trulock EP, Pfeifer JD, Ritter JH, Gaudreault-Keener M, Storch GA, Holtzman MJ. Detection of severe human metapneumovirus infection by real-time polymerase chain reaction and histopathological assessment. The Journal of Infectious Diseases. 192: 1052-60. PMID 16107959 DOI: 10.1086/432728 |
0.335 |
|
| 2005 |
Zhang Y, Takami K, Lo MS, Huang G, Yu Q, Roswit WT, Holtzman MJ. Modification of the Stat1 SH2 domain broadly improves interferon efficacy in proportion to p300/CREB-binding protein coactivator recruitment. The Journal of Biological Chemistry. 280: 34306-15. PMID 16107341 DOI: 10.1074/Jbc.M503263200 |
0.642 |
|
| 2005 |
Holtzman MJ, Kim EY, Lo MS, Tyner JW, Shornick LP, Sumino KC, Zhang Y. Defining and adjusting divergent host responses to viral infection. Immunologic Research. 32: 123-41. PMID 16106064 DOI: 10.1385/Ir:32:1-3:123 |
0.788 |
|
| 2005 |
Lo MS, Brazas RM, Holtzman MJ. Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness. Journal of Virology. 79: 9315-9. PMID 15994826 DOI: 10.1128/Jvi.79.14.9315-9319.2005 |
0.656 |
|
| 2005 |
Walter MJ, Holtzman MJ. A centennial history of research on asthma pathogenesis. American Journal of Respiratory Cell and Molecular Biology. 32: 483-9. PMID 15901618 DOI: 10.1165/Rcmb.F300 |
0.389 |
|
| 2004 |
Holtzman MJ, Shornick LP, Grayson MH, Kim EY, Tyner JW, Patel AC, Agapov E, Zhang Y. "Hit-and-run" effects of paramyxoviruses as a basis for chronic respiratory disease. The Pediatric Infectious Disease Journal. 23: S235-45. PMID 15577579 DOI: 10.1097/01.Inf.0000144674.24802.C1 |
0.702 |
|
| 2004 |
Castro M, Bloch SR, Jenkerson MV, DeMartino S, Hamilos DL, Cochran RB, Zhang XE, Wang H, Bradley JP, Schechtman KB, Holtzman MJ. Asthma exacerbations after glucocorticoid withdrawal reflects T cell recruitment to the airway. American Journal of Respiratory and Critical Care Medicine. 169: 842-9. PMID 14726420 DOI: 10.1164/Rccm.200208-960Oc |
0.387 |
|
| 2003 |
Holtzman MJ. Drug development for asthma. American Journal of Respiratory Cell and Molecular Biology. 29: 163-71. PMID 12878583 DOI: 10.1165/Rcmb.F276 |
0.382 |
|
| 2003 |
O'Sullivan MP, Tyner JW, Holtzman MJ. Apoptosis in the airways: another balancing act in the epithelial program. American Journal of Respiratory Cell and Molecular Biology. 29: 3-7. PMID 12821445 DOI: 10.1165/Rcmb.F273 |
0.622 |
|
| 2003 |
Holtzman MJ, Agapov E, Kim E, Kim JI, Morton JD. Developing the epithelial, viral, and allergic paradigm for asthma: Giles F. Filley lecture. Chest. 123: 377S-84S. PMID 12628993 DOI: 10.1378/Chest.123.3_Suppl.377S |
0.562 |
|
| 2003 |
Grayson M, Rohlfing M, Holtzman M. Dendritic cell homing to murine lung is not CCL5 or CCR5 dependent Journal of Allergy and Clinical Immunology. 111: S152. DOI: 10.1016/S0091-6749(03)80489-X |
0.339 |
|
| 2002 |
Stephens R, Randolph DA, Huang G, Holtzman MJ, Chaplin DD. Antigen-nonspecific recruitment of Th2 cells to the lung as a mechanism for viral infection-induced allergic asthma. Journal of Immunology (Baltimore, Md. : 1950). 169: 5458-67. PMID 12421921 DOI: 10.4049/Jimmunol.169.10.5458 |
0.44 |
|
| 2002 |
Walter MJ, Morton JD, Kajiwara N, Agapov E, Holtzman MJ. Viral induction of a chronic asthma phenotype and genetic segregation from the acute response. The Journal of Clinical Investigation. 110: 165-75. PMID 12122108 DOI: 10.1172/Jci14345 |
0.466 |
|
| 2002 |
Holtzman MJ, Morton JD, Shornick LP, Tyner JW, O'Sullivan MP, Antao A, Lo M, Castro M, Walter MJ. Immunity, inflammation, and remodeling in the airway epithelial barrier: epithelial-viral-allergic paradigm. Physiological Reviews. 82: 19-46. PMID 11773608 DOI: 10.1152/Physrev.00020.2001 |
0.766 |
|
| 2002 |
Grayson MH, Holtzman MJ. Lessons from allergic rhinitis versus asthma pathogenesis and treatment Immunology and Allergy Clinics of North America. 22: 845-869. DOI: 10.1016/S0889-8561(02)00027-9 |
0.447 |
|
| 2001 |
Walter MJ, Kajiwara N, Karanja P, Castro M, Holtzman MJ. Interleukin 12 p40 production by barrier epithelial cells during airway inflammation Journal of Experimental Medicine. 193: 339-351. PMID 11157054 DOI: 10.1084/Jem.193.3.339 |
0.404 |
|
| 2000 |
Castro M, Chaplin DD, Walter MJ, Holtzman MJ. Could asthma be worsened by stimulating the T-helper type 1 immune response? American Journal of Respiratory Cell and Molecular Biology. 22: 143-146. PMID 10657933 DOI: 10.1165/Ajrcmb.22.2.F174 |
0.412 |
|
| 1999 |
Koga T, Sardiña E, Tidwell RM, Pelletier M, Look DC, Holtzman MJ. Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization Proceedings of the National Academy of Sciences of the United States of America. 96: 5680-5685. PMID 10318944 DOI: 10.1073/Pnas.96.10.5680 |
0.398 |
|
| 1999 |
Sampath D, Castro M, Look DC, Holtzman MJ. Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. The Journal of Clinical Investigation. 103: 1353-61. PMID 10225979 DOI: 10.1172/JCI6130 |
0.308 |
|
| 1998 |
Look DC, Roswit WT, Frick AG, Gris-Alevy Y, Dickhaus DM, Walter MJ, Holtzman MJ. Direct suppression of Stat1 function during adenoviral infection. Immunity. 9: 871-80. PMID 9881977 DOI: 10.1016/S1074-7613(00)80652-4 |
0.364 |
|
| 1998 |
Taguchi M, Sampath D, Koga T, Castro M, Look DC, Nakajima S, Holtzman MJ. Patterns for RANTES secretion and intercellular adhesion molecule 1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo. The Journal of Experimental Medicine. 187: 1927-40. PMID 9625753 DOI: 10.1084/Jem.187.12.1927 |
0.384 |
|
| 1998 |
Holtzman MJ, Look DC, Sampath D, Castro M, Koga T, Walter MJ. Control of epithelial immune-response genes and implications for airway immunity and inflammation. Proceedings of the Association of American Physicians. 110: 1-11. PMID 9460078 |
0.41 |
|
| 1998 |
Walter MJ, Kajiwara N, Sampath D, Rucker J, Holtzman MJ. Induction of epithelial immune-response genes in a mouse model of viral bronchitis and hyperreactivity Faseb Journal. 12. |
0.394 |
|
| 1997 |
Walter MJ, Look DC, Tidwell RM, Roswit WT, Holtzman MJ. Targeted inhibition of interferon-γ-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1 Journal of Biological Chemistry. 272: 28582-28589. PMID 9353323 DOI: 10.1074/Jbc.272.45.28582 |
0.361 |
|
| 1996 |
Holtzman MJ, Sampath D, Castro M, Look DC, Jayaraman S. The one-two of T helper cells: does interferon-gamma knock out the Th2 hypothesis for asthma? American Journal of Respiratory Cell and Molecular Biology. 14: 316-8. PMID 8600934 DOI: 10.1165/Ajrcmb.14.4.8600934 |
0.418 |
|
| 1995 |
Holtzman MJ, Brody SL, Look DC. Does gene therapy call for "STAT" immunity and inflammation at the epithelial barrier? American Journal of Respiratory Cell and Molecular Biology. 12: 127-129. PMID 7865211 DOI: 10.1165/Ajrcmb.12.2.7865211 |
0.437 |
|
| 1994 |
Holtzman MJ, Zhang V, Hussain H, Roswit WT, Wilson JD. Prostaglandin H synthase and lipoxygenase gene families in the epithelial cell barrier. Annals of the New York Academy of Sciences. 744: 58-77. PMID 7825863 DOI: 10.1111/J.1749-6632.1994.Tb52724.X |
0.327 |
|
| 1993 |
Shannon VR, Chanez P, Bousquet J, Holtzman MJ. Histochemical evidence for induction of arachidonate 15-lipoxygenase in airway disease American Review of Respiratory Disease. 147: 1024-1028. PMID 8466102 DOI: 10.1164/Ajrccm/147.4.1024 |
0.359 |
|
| 1993 |
Shannon VR, Stenson WF, Holtzman MJ. Induction of epithelial arachidonate 12-lipoxygenase at active sites of inflammatory bowel disease American Journal of Physiology - Gastrointestinal and Liver Physiology. 264. PMID 7679252 DOI: 10.1152/Ajpgi.1993.264.1.G104 |
0.325 |
|
| 1992 |
Holtzman MJ. Arachidonic acid metabolism in airway epithelial cells Annual Review of Physiology. 54: 303-329. PMID 1562177 DOI: 10.1146/Annurev.Ph.54.030192.001511 |
0.35 |
|
| 1992 |
Holtzman MJ, Look DC. Cell adhesion molecules as targets for unraveling the genetic regulation of airway inflammation American Journal of Respiratory Cell and Molecular Biology. 7: 246-247. PMID 1520488 DOI: 10.1165/Ajrcmb/7.3.246 |
0.324 |
|
| 1992 |
Look DC, Rapp SR, Keller BT, Holtzman MJ. Selective induction of intercellular adhesion molecule-1 by interferon-γ in human airway epithelial cells American Journal of Physiology - Lung Cellular and Molecular Physiology. 263. PMID 1353306 DOI: 10.1152/Ajplung.1992.263.1.L79 |
0.383 |
|
| 1991 |
Shannon VR, Crouch EC, Takahashi Y, Ueda N, Yamamoto S, Holtzman MJ. Related expression of arachidonate 12- and 15-lipoxygenases in animal and human lung tissue American Journal of Physiology - Lung Cellular and Molecular Physiology. 261. PMID 1767860 DOI: 10.1152/Ajplung.1991.261.6.L399 |
0.337 |
|
| 1989 |
Holtzman MJ, Pentland A, Baenziger NL, Hansbrough JR. Heterogeneity of cellular expression of arachidonate 15-lipoxygenase: implications for biological activity. Biochimica Et Biophysica Acta. 1003: 204-8. PMID 2730892 DOI: 10.1016/0005-2760(89)90257-9 |
0.314 |
|
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