| Year |
Citation |
Score |
| 2020 |
Liang F, Miller AS, Tang C, Maranon D, Williamson EA, Hromas R, Wiese C, Zhao W, Sung P, Kupfer GM. The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair. The Journal of Biological Chemistry. PMID 32350107 DOI: 10.1074/Jbc.Ra120.013714 |
0.321 |
|
| 2020 |
Ghayee HK, Rai S, Bril F, Hatch H, Xu Y, Kalavalapalli S, Garrett T, Plant D, Bose P, Hromas R, Cusi K, Tischler A, Gupta P, Bibb J, Beuschlein F, et al. MON-199 Targeting Pheochromocytoma/Paraganglioma with Polyamine Inhibitors Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1165 |
0.318 |
|
| 2020 |
George TJ, DeRemer DL, Parekh HD, Lee J, Markham MJ, Daily KC, Kaye FJ, Staal S, Jones DV, Stechmiller BK, Allegra CJ, Hromas RA. Phase II trial of the PARP inhibitor, niraparib, in BAP1 and other DNA damage response (DDR) pathway deficient neoplasms including cholangiocarcinoma. Journal of Clinical Oncology. 38: TPS591-TPS591. DOI: 10.1200/Jco.2020.38.4_Suppl.Tps591 |
0.316 |
|
| 2020 |
ali a, DeRemer DL, Lee J, Parekh HD, Staal S, Markham MJ, Daily KC, Stechmiller BK, Jones DV, Close JL, Murphy MC, Kaye FJ, Allegra CJ, Hromas RA, George TJ. Phase II trial of the PARP inhibitor, niraparib, in BAP1 and other DNA damage response (DDR) pathway deficient neoplasms (NCT03207347). Journal of Clinical Oncology. 38: e22061-e22061. DOI: 10.1200/Jco.2020.38.15_Suppl.E22061 |
0.334 |
|
| 2019 |
Jaiswal AS, Williamson EA, Srinivasan G, Kong K, Lomelino CL, McKenna R, Walter C, Sung P, Narayan S, Hromas R. The splicing component ISY1 regulates APE1 in base excision repair. Dna Repair. 86: 102769. PMID 31887540 DOI: 10.1016/J.Dnarep.2019.102769 |
0.34 |
|
| 2019 |
Srinivasan G, Williamson EA, Kong K, Jaiswal AS, Huang G, Kim HS, Schärer O, Zhao W, Burma S, Sung P, Hromas R. MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 31395736 DOI: 10.1073/Pnas.1903150116 |
0.313 |
|
| 2019 |
Liang F, Miller AS, Longerich S, Tang C, Maranon D, Williamson EA, Hromas R, Wiese C, Kupfer GM, Sung P. DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response. Nature Communications. 10: 2849. PMID 31253762 DOI: 10.1038/S41467-019-10408-5 |
0.32 |
|
| 2019 |
Jaiswal A, Williamson E, Patel B, Srinivasan G, Kong K, Lomelino C, Narayan S, Hromas R. Abstract 1758: Splicing component ISY1 interacts with APE1 and regulates base excision repair Cancer Research. 79: 1758-1758. DOI: 10.1158/1538-7445.Sabcs18-1758 |
0.34 |
|
| 2018 |
Khan S, Zhang X, Lv D, He Y, Zhang P, Liu X, Thummuri D, Zhang Q, Konopleva MY, Hromas RA, Zheng G, Zhou D. DT2216, a Synthetic Proteolytic Selectively Targeting Bcl-XL for Ubiquitination and Degradation in Tumor Cells but Not in Platelets, Is a Safer and More Potent Antitumor Agent Than Navitoclax Blood. 132: 2698-2698. DOI: 10.1182/Blood-2018-99-114762 |
0.333 |
|
| 2017 |
Narayan S, Jaiswal AS, Sharma R, Nawab A, Duckworth LV, Law BK, Zajac-Kaye M, George TJ, Sharma J, Sharma AK, Hromas RA. NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations. Oncotarget. 8: 57246-57264. PMID 28915668 DOI: 10.18632/Oncotarget.19778 |
0.39 |
|
| 2017 |
Srinivasan G, Sidhu GS, Williamson EA, Jaiswal AS, Najmunnisa N, Wilcoxen K, Jones D, George TJ, Hromas R. Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition. Cancer Chemotherapy and Pharmacology. PMID 28756516 DOI: 10.1007/S00280-017-3401-Y |
0.366 |
|
| 2017 |
Nickoloff JA, Jones D, Lee SH, Williamson EA, Hromas R. Drugging the Cancers Addicted to DNA Repair. Journal of the National Cancer Institute. 109. PMID 28521333 DOI: 10.1093/Jnci/Djx059 |
0.306 |
|
| 2017 |
Srinivasan G, Williamson E, Hromas R. Abstract A35: Precision targeting of Homologous Recombination-deficient cancers using microRNA synthetic lethality Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-A35 |
0.305 |
|
| 2016 |
Kim HS, Williamson EA, Nickoloff JA, Hromas RA, Lee SH. Metnase Mediates Loading of Exonuclease 1 onto Single-strand Overhang DNA for End Resection at Stalled Replication Forks. The Journal of Biological Chemistry. PMID 27974460 DOI: 10.1074/Jbc.M116.745646 |
0.314 |
|
| 2016 |
Narayan S, Jaiswal AS, Law BK, Kamal MA, Sharma AK, Hromas RA. Interaction between APC and Fen1 during breast carcinogenesis. Dna Repair. 41: 54-62. PMID 27088617 DOI: 10.1016/J.Dnarep.2016.04.003 |
0.326 |
|
| 2016 |
Sullivan K, Cramer-Morales K, McElroy DL, Ostrov DA, Haas K, Childers W, Hromas R, Skorski T. Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection. Plos One. 11: e0147230. PMID 26784987 DOI: 10.1371/Journal.Pone.0147230 |
0.302 |
|
| 2015 |
Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, ... ... Hromas RA, et al. EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair. Plos Genetics. 11: e1005675. PMID 26684013 DOI: 10.1371/Journal.Pgen.1005675 |
0.32 |
|
| 2015 |
Kim HS, Kim SK, Hromas R, Lee SH. The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5' End of SS-Overhang Cleavage. Plos One. 10: e0139418. PMID 26437079 DOI: 10.1371/Journal.Pone.0139418 |
0.305 |
|
| 2015 |
Jaiswal AS, Panda H, Law BK, Sharma J, Jani J, Hromas R, Narayan S. NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells. Plos One. 10: e0123808. PMID 25933036 DOI: 10.1371/Journal.Pone.0123808 |
0.33 |
|
| 2015 |
Sullivan K, Cramer-Morales K, McElroy DL, Ostrov D, Haas K, Nieborowska-Skorska M, Childers W, Mazin A, Hromas RA, Pomerantz R, Skorski T. Identification of a Small Molecule Inhibitor of RAD52 to Induce Synthetic Lethality in BRCA-Deficient Leukemias Blood. 126: 4434-4434. DOI: 10.1182/Blood.V126.23.4434.4434 |
0.39 |
|
| 2014 |
Williamson EA, Wu Y, Singh S, Byrne M, Wray J, Lee SH, Nickoloff JA, Hromas R. The DNA repair component Metnase regulates Chk1 stability. Cell Division. 9: 1. PMID 25024738 DOI: 10.1186/1747-1028-9-1 |
0.317 |
|
| 2014 |
Shanmugam I, Abbas M, Ayoub F, Mirabal S, Bsaili M, Caulder EK, Weinstock DM, Tomkinson AE, Hromas R, Shaheen M. Ubiquitin-specific peptidase 20 regulates Rad17 stability, checkpoint kinase 1 phosphorylation and DNA repair by homologous recombination. The Journal of Biological Chemistry. 289: 22739-48. PMID 24923443 DOI: 10.1074/Jbc.M114.550459 |
0.333 |
|
| 2014 |
Abbas M, Shanmugam I, Bsaili M, Hromas R, Shaheen M. The role of the human psoralen 4 (hPso4) protein complex in replication stress and homologous recombination. The Journal of Biological Chemistry. 289: 14009-19. PMID 24675077 DOI: 10.1074/Jbc.M113.520056 |
0.349 |
|
| 2014 |
Rath A, Hromas R, De Benedetti A. Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing. Bmc Molecular Biology. 15: 6. PMID 24655462 DOI: 10.1186/1471-2199-15-6 |
0.34 |
|
| 2014 |
Cogle CR, Goldman DC, Madlambayan GJ, Leon RP, Al Masri A, Clark HA, Asbaghi SA, Tyner JW, Dunlap J, Fan G, Kovacsovics T, Liu Q, Meacham A, Hamlin KL, Hromas RA, et al. Functional integration of acute myeloid leukemia into the vascular niche. Leukemia. 28: 1978-87. PMID 24637335 DOI: 10.1038/Leu.2014.109 |
0.355 |
|
| 2014 |
Kim HS, Chen Q, Kim SK, Nickoloff JA, Hromas R, Georgiadis MM, Lee SH. The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart. The Journal of Biological Chemistry. 289: 10930-8. PMID 24573677 DOI: 10.1074/Jbc.M113.533216 |
0.302 |
|
| 2014 |
Byrne M, Wray J, Reinert B, Wu Y, Nickoloff J, Lee SH, Hromas R, Williamson E. Mechanisms of oncogenic chromosomal translocations. Annals of the New York Academy of Sciences. 1310: 89-97. PMID 24528169 DOI: 10.1111/Nyas.12370 |
0.31 |
|
| 2014 |
Wu Y, Lee S, Williamson EA, Reinert BL, Srinivasan G, Singh S, Jaiswal A, Tornaletti S, Brantly AC, Hromas RA. Abstract 2427: The 5′ endonuclease EEPD1 maintains genomic stability by mediating DNA repair pathway choice Cancer Research. 74: 2427-2427. DOI: 10.1158/1538-7445.Am2014-2427 |
0.364 |
|
| 2013 |
Williamson EA, Hromas R. Repressing DNA repair to enhance chemotherapy: targeting MyD88 in colon cancer. Journal of the National Cancer Institute. 105: 926-7. PMID 23766531 DOI: 10.1093/Jnci/Djt148 |
0.377 |
|
| 2013 |
Mohapatra S, Yannone SM, Lee SH, Hromas RA, Akopiants K, Menon V, Ramsden DA, Povirk LF. Trimming of damaged 3' overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases. Dna Repair. 12: 422-32. PMID 23602515 DOI: 10.1016/J.Dnarep.2013.03.005 |
0.331 |
|
| 2013 |
Wray J, Williamson EA, Singh SB, Wu Y, Cogle CR, Weinstock DM, Zhang Y, Lee SH, Zhou D, Shao L, Hauer-Jensen M, Pathak R, Klimek V, Nickoloff JA, Hromas R. PARP1 is required for chromosomal translocations. Blood. 121: 4359-65. PMID 23568489 DOI: 10.1182/Blood-2012-10-460527 |
0.314 |
|
| 2013 |
Jaiswal AS, Panda H, Pampo CA, Siemann DW, Gairola CG, Hromas R, Narayan S. Adenomatous polyposis coli-mediated accumulation of abasic DNA lesions lead to cigarette smoke condensate-induced neoplastic transformation of normal breast epithelial cells. Neoplasia (New York, N.Y.). 15: 454-60. PMID 23555190 DOI: 10.1593/Neo.13176 |
0.39 |
|
| 2012 |
Williamson EA, Damiani L, Leitao A, Hu C, Hathaway H, Oprea T, Sklar L, Shaheen M, Bauman J, Wang W, Nickoloff JA, Lee SH, Hromas R. Targeting the transposase domain of the DNA repair component metnase to enhance chemotherapy Cancer Research. 72: 6200-6208. PMID 23090115 DOI: 10.1158/0008-5472.Can-12-0313 |
0.336 |
|
| 2012 |
Williamson EA, Wray JW, Bansal P, Hromas R. Overview for the histone codes for DNA repair. Progress in Molecular Biology and Translational Science. 110: 207-27. PMID 22749147 DOI: 10.1016/B978-0-12-387665-2.00008-0 |
0.312 |
|
| 2012 |
Hromas R, Williamson EA, Fnu S, Lee YJ, Park SJ, Beck BD, You JS, Leitao A, Laitao A, Nickoloff JA, Lee SH. Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart. Oncogene. 31: 4245-54. PMID 22231448 DOI: 10.1038/Onc.2011.586 |
0.313 |
|
| 2012 |
Bauman JE, Olson GT, Spafford M, Nuara M, Sampath S, Lee S, Williamson EA, Wu Y, Sklar LA, Oprea TI, Hromas R. A pilot study of raltegravir and cisplatin in head and neck squamous cell carcinoma (HNSCC). Journal of Clinical Oncology. 30: TPS5602-TPS5602. DOI: 10.1200/Jco.2012.30.15_Suppl.Tps5602 |
0.328 |
|
| 2011 |
Ponder J, Yoo BH, Abraham AD, Li Q, Ashley AK, Amerin CL, Zhou Q, Reid BG, Reigan P, Hromas R, Nickoloff JA, LaBarbera DV. Neoamphimedine circumvents metnase-enhanced DNA topoisomerase IIα activity through ATP-competitive inhibition. Marine Drugs. 9: 2397-408. PMID 22163192 DOI: 10.3390/Md9112397 |
0.352 |
|
| 2011 |
Beck BD, Lee SS, Williamson E, Hromas RA, Lee SH. Biochemical characterization of metnase's endonuclease activity and its role in NHEJ repair. Biochemistry. 50: 4360-70. PMID 21491884 DOI: 10.1021/Bi200333K |
0.367 |
|
| 2011 |
Shaheen M, Allen C, Nickoloff JA, Hromas R. Synthetic lethality: exploiting the addiction of cancer to DNA repair. Blood. 117: 6074-82. PMID 21441464 DOI: 10.1182/Blood-2011-01-313734 |
0.338 |
|
| 2011 |
Allen C, Ashley AK, Hromas R, Nickoloff JA. More forks on the road to replication stress recovery. Journal of Molecular Cell Biology. 3: 4-12. PMID 21278446 DOI: 10.1093/Jmcb/Mjq049 |
0.32 |
|
| 2011 |
Fnu S, Williamson EA, De Haro LP, Brenneman M, Wray J, Shaheen M, Radhakrishnan K, Lee SH, Nickoloff JA, Hromas R. Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining. Proceedings of the National Academy of Sciences of the United States of America. 108: 540-5. PMID 21187428 DOI: 10.1073/Pnas.1013571108 |
0.316 |
|
| 2010 |
Shaheen M, Shanmugam I, Hromas R. The Role of PCNA Posttranslational Modifications in Translesion Synthesis. Journal of Nucleic Acids. 2010. PMID 20847899 DOI: 10.4061/2010/761217 |
0.301 |
|
| 2010 |
Wray J, Williamson EA, Chester S, Farrington J, Sterk R, Weinstock DM, Jasin M, Lee SH, Nickoloff JA, Hromas R. The transposase domain protein Metnase/SETMAR suppresses chromosomal translocations. Cancer Genetics and Cytogenetics. 200: 184-90. PMID 20620605 DOI: 10.1016/J.Cancergencyto.2010.04.011 |
0.372 |
|
| 2010 |
De Haro LP, Wray J, Williamson EA, Durant ST, Corwin L, Gentry AC, Osheroff N, Lee SH, Hromas R, Nickoloff JA. Metnase promotes restart and repair of stalled and collapsed replication forks. Nucleic Acids Research. 38: 5681-91. PMID 20457750 DOI: 10.1093/Nar/Gkq339 |
0.369 |
|
| 2010 |
Beck BD, Lee SS, Hromas R, Lee SH. Regulation of Metnase's TIR binding activity by its binding partner, Pso4. Archives of Biochemistry and Biophysics. 498: 89-94. PMID 20416268 DOI: 10.1016/J.Abb.2010.04.011 |
0.318 |
|
| 2010 |
Shaheen M, Williamson E, Nickoloff J, Lee SH, Hromas R. Metnase/SETMAR: a domesticated primate transposase that enhances DNA repair, replication, and decatenation. Genetica. 138: 559-66. PMID 20309721 DOI: 10.1007/S10709-010-9452-1 |
0.336 |
|
| 2009 |
Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, et al. Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Molecular and Cellular Biology. 29: 5911-22. PMID 19704007 DOI: 10.1128/Mcb.00558-09 |
0.329 |
|
| 2009 |
Wray J, Williamson EA, Sheema S, Lee SH, Libby E, Willman CL, Nickoloff JA, Hromas R. Metnase mediates chromosome decatenation in acute leukemia cells. Blood. 114: 1852-8. PMID 19458360 DOI: 10.1182/Blood-2008-08-175760 |
0.401 |
|
| 2009 |
Wray J, Williamson EA, Royce M, Shaheen M, Beck BD, Lee SH, Nickoloff JA, Hromas R. Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells. Plos One. 4: e5323. PMID 19390626 DOI: 10.1371/Journal.Pone.0005323 |
0.326 |
|
| 2009 |
Kong KY, Williamson EA, Rogers JH, Tran T, Hromas R, Dahl R. Expression of Scl in mesoderm rescues hematopoiesis in the absence of Oct-4. Blood. 114: 60-3. PMID 19321862 DOI: 10.1182/Blood-2008-08-174755 |
0.4 |
|
| 2008 |
Williamson EA, Rasila KK, Corwin LK, Wray J, Beck BD, Severns V, Mobarak C, Lee SH, Nickoloff JA, Hromas R. The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation. Nucleic Acids Research. 36: 5822-31. PMID 18790802 DOI: 10.1093/Nar/Gkn560 |
0.346 |
|
| 2008 |
Hromas R, Wray J, Lee SH, Martinez L, Farrington J, Corwin LK, Ramsey H, Nickoloff JA, Williamson EA. The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining. Dna Repair. 7: 1927-37. PMID 18773976 DOI: 10.1016/J.Dnarep.2008.08.002 |
0.336 |
|
| 2008 |
Williamson EA, Farrington J, Martinez L, Ness S, O'Rourke J, Lee SH, Nickoloff J, Hromas R. Expression levels of the human DNA repair protein metnase influence lentiviral genomic integration. Biochimie. 90: 1422-6. PMID 18549821 DOI: 10.1016/J.Biochi.2008.05.010 |
0.323 |
|
| 2008 |
Beck BD, Park SJ, Lee YJ, Roman Y, Hromas RA, Lee SH. Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair. The Journal of Biological Chemistry. 283: 9023-30. PMID 18263876 DOI: 10.1074/Jbc.M800150200 |
0.337 |
|
| 2008 |
Guo Y, Mantel C, Hromas RA, Broxmeyer HE. Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells (Dayton, Ohio). 26: 30-4. PMID 17932422 DOI: 10.1634/Stemcells.2007-0401 |
0.408 |
|
| 2008 |
Rogers JH, Owens KS, Vargas JM, Willman CL, Hromas R, Dahl R. Pediatric Acute Lymphoblastic Leukemia Outcome Predictor Genes OPAL1 and RANTES Modulate Transformation by the V-Abl Oncogene Blood. 112: 5318-5318. DOI: 10.1182/Blood.V112.11.5318.5318 |
0.339 |
|
| 2007 |
Roman Y, Oshige M, Lee YJ, Goodwin K, Georgiadis MM, Hromas RA, Lee SH. Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity. Biochemistry. 46: 11369-76. PMID 17877369 DOI: 10.1021/Bi7005477 |
0.322 |
|
| 2006 |
Starnes T, Rasila KK, Robertson MJ, Brahmi Z, Dahl R, Christopherson K, Hromas R. The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: implications for the downregulation of CXCL14 in malignancy. Experimental Hematology. 34: 1101-5. PMID 16863917 DOI: 10.1016/J.Exphem.2006.05.015 |
0.762 |
|
| 2006 |
Broxmeyer HE, Pelus LM, Kim CH, Hangoc G, Cooper S, Hromas R. Synergistic inhibition in vivo of bone marrow myeloid progenitors by myelosuppressive chemokines and chemokine-accelerated recovery of progenitors after treatment of mice with Ara-C. Experimental Hematology. 34: 1069-77. PMID 16863913 DOI: 10.1016/J.Exphem.2006.04.007 |
0.338 |
|
| 2006 |
Chan RJ, Hromas R, Yoder MC. The role of Hex in hemangioblast and hematopoietic development. Methods in Molecular Biology (Clifton, N.J.). 330: 123-33. PMID 16846021 DOI: 10.1385/1-59745-036-7:123 |
0.337 |
|
| 2006 |
Broxmeyer HE, Starnes T, Ramsey H, Cooper S, Dahl R, Williamson E, Hromas R. The IL-17 cytokine family members are inhibitors of human hematopoietic progenitor proliferation. Blood. 108: 770. PMID 16822904 DOI: 10.1182/Blood-2006-01-0292 |
0.755 |
|
| 2006 |
Guo Y, Mantel C, Hromas RA, Broxmeyer HE. Oct-4 Is Crucial for Stress-Induced Murine Embryonic Stem Cell Survival/Anti-Apoptosis Mediated by STAT3/Survivin. Blood. 108: 277-277. DOI: 10.1182/Blood.V108.11.277.277 |
0.383 |
|
| 2005 |
Lee SH, Oshige M, Durant ST, Rasila KK, Williamson EA, Ramsey H, Kwan L, Nickoloff JA, Hromas R. The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair. Proceedings of the National Academy of Sciences of the United States of America. 102: 18075-80. PMID 16332963 DOI: 10.1073/Pnas.0503676102 |
0.326 |
|
| 2005 |
Juric D, Sale S, Hromas RA, Yu R, Wang Y, Duran GE, Tibshirani R, Einhorn LH, Sikic BI. Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures. Proceedings of the National Academy of Sciences of the United States of America. 102: 17763-8. PMID 16306258 DOI: 10.1073/Pnas.0509082102 |
0.335 |
|
| 2005 |
Robertson MJ, Abonour R, Hromas R, Nelson RP, Fineberg NS, Cornetta K. Augmented high-dose regimen of cyclophosphamide, carmustine, and etoposide with autologous hematopoietic stem cell transplantation for relapsed and refractory aggressive non-Hodgkin's lymphoma. Leukemia & Lymphoma. 46: 1477-87. PMID 16194894 DOI: 10.1080/10428190500158466 |
0.316 |
|
| 2005 |
Chan EM, Comer EM, Brown FC, Richkind KE, Holmes ML, Chong BH, Shiffman R, Zhang DE, Slovak ML, Willman CL, Noguchi CT, Li Y, Heiber DJ, Kwan L, Chan RJ, ... ... Hromas RA, et al. AML1-FOG2 fusion protein in myelodysplasia. Blood. 105: 4523-6. PMID 15705784 DOI: 10.1182/Blood-2004-07-2762 |
0.36 |
|
| 2005 |
Hou YH, Srour EF, Ramsey H, Dahl R, Broxmeyer HE, Hromas R. Identification of a human B-cell/myeloid common progenitor by the absence of CXCR4. Blood. 105: 3488-92. PMID 15650059 DOI: 10.1182/Blood-2004-07-2839 |
0.591 |
|
| 2005 |
Mantel CR, Guo Y, Han M, Roharbaugh S, Graham-Evans B, Yoder MC, Hromas RA, Broxmeyer HE. oct-4 Is Essential for Aneuploidy/Polyploidy-Tolerance in Embryonic Stem (ES) Cells and the Fate of Tetraploid ES Cells during Early Differentiation. Blood. 106: 311-311. DOI: 10.1182/Blood.V106.11.311.311 |
0.39 |
|
| 2005 |
Guo Y, Graham-Evans B, Mantal CR, Hromas RA, Broxmeyer HE. Oct-4 Is Crucial for Murine Embryonic Stem Cell Secretion of Cytokines/Growth Modulators That Enhance Cell Survival/Anti-Apoptosis of Murine ES Cells and Bone Marrow Hematopoietic Progenitor Cells. Blood. 106: 1359-1359. DOI: 10.1182/Blood.V106.11.1359.1359 |
0.414 |
|
| 2004 |
Ramsey H, Christopherson K, Hromas R. Forced expression of AML1-AMP19, a fusion transcript generated from a radiation-associated t(19;21) leukemia, blocks myeloid differentiation. Leukemia Research. 28: 863-8. PMID 15203284 DOI: 10.1016/J.Leukres.2003.12.011 |
0.672 |
|
| 2004 |
Christopherson KW, Hromas RA. Endothelial chemokines in autoimmune disease. Current Pharmaceutical Design. 10: 145-54. PMID 14754394 DOI: 10.2174/1381612043453405 |
0.617 |
|
| 2003 |
Guo Y, Chan R, Ramsey H, Li W, Xie X, Shelley WC, Martinez-Barbera JP, Bort B, Zaret K, Yoder M, Hromas R. The homeoprotein Hex is required for hemangioblast differentiation. Blood. 102: 2428-35. PMID 12791650 DOI: 10.1182/Blood-2003-02-0634 |
0.377 |
|
| 2003 |
Christopherson KW, Hood AF, Travers JB, Ramsey H, Hromas RA. Endothelial induction of the T-cell chemokine CCL21 in T-cell autoimmune diseases. Blood. 101: 801-6. PMID 12393410 DOI: 10.1182/Blood-2002-05-1586 |
0.663 |
|
| 2002 |
Mack DL, Leibowitz DS, Cooper S, Ramsey H, Broxmeyer HE, Hromas R. Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development Immunology. 107: 444-451. PMID 12460189 DOI: 10.1046/J.1365-2567.2002.01523.X |
0.411 |
|
| 2002 |
Hromas R, Cooper S, Broxmeyer HE. The chemokine CCL21 protects normal marrow progenitors from ara-C cytotoxicity Cancer Chemotherapy and Pharmacology. 50: 163-166. PMID 12172984 DOI: 10.1007/S00280-002-0486-7 |
0.336 |
|
| 2002 |
Starnes T, Broxmeyer HE, Robertson MJ, Hromas R. Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis. Journal of Immunology (Baltimore, Md. : 1950). 169: 642-6. PMID 12097364 DOI: 10.4049/Jimmunol.169.2.642 |
0.737 |
|
| 2002 |
Christopherson KW, Campbell JJ, Travers JB, Hromas RA. Low-molecular-weight heparins inhibit CCL21-induced T cell adhesion and migration. The Journal of Pharmacology and Experimental Therapeutics. 302: 290-5. PMID 12065729 DOI: 10.1124/Jpet.302.1.290 |
0.634 |
|
| 2002 |
Guo Y, Costa R, Ramsey H, Starnes T, Vance G, Robertson K, Kelley M, Reinbold R, Scholer H, Hromas R. The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression. Proceedings of the National Academy of Sciences of the United States of America. 99: 3663-7. PMID 11891324 DOI: 10.1073/Pnas.062041099 |
0.763 |
|
| 2001 |
Christopherson KW, Campbell JJ, Hromas RA. Transgenic overexpression of the CC chemokine CCL21 disrupts T-cell migration. Blood. 98: 3562-8. PMID 11739157 DOI: 10.1182/Blood.V98.13.3562 |
0.641 |
|
| 2001 |
Starnes T, Robertson MJ, Sledge G, Kelich S, Nakshatri H, Broxmeyer HE, Hromas R. Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 167: 4137-40. PMID 11591732 DOI: 10.4049/Jimmunol.167.8.4137 |
0.754 |
|
| 2001 |
Christopherson K, Hromas R. Chemokine regulation of normal and pathologic immune responses. Stem Cells (Dayton, Ohio). 19: 388-96. PMID 11553847 DOI: 10.1634/Stemcells.19-5-388 |
0.662 |
|
| 2001 |
Hromas R, Busse T, Carroll A, Mack D, Shopnick R, Zhang DE, Nakshatri H, Richkind K. Fusion AML1 transcript in a radiation-associated leukemia results in a truncated inhibitory AML1 protein. Blood. 97: 2168-70. PMID 11264187 DOI: 10.1182/Blood.V97.7.2168 |
0.324 |
|
| 2001 |
Hromas R. Pumped on steroids Blood. 98: 3177-3178. DOI: 10.1182/Blood.V98.12.3177B |
0.31 |
|
| 2000 |
Abonour R, Williams DA, Einhorn L, Hall KM, Chen J, Coffman J, Traycoff CM, Bank A, Kato I, Ward M, Williams SD, Hromas R, Robertson MJ, Smith FO, Woo D, et al. Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells. Nature Medicine. 6: 652-8. PMID 10835681 DOI: 10.1038/76225 |
0.356 |
|
| 2000 |
Braun SE, Chen K, Foster RG, Kim CH, Hromas R, Kaplan MH, Broxmeyer HE, Cornetta K. The CC chemokine CK beta-11/MIP-3 beta/ELC/Exodus 3 mediates tumor rejection of murine breast cancer cells through NK cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 4025-31. PMID 10754294 DOI: 10.4049/Jimmunol.164.8.4025 |
0.307 |
|
| 2000 |
Robertson MJ, Williams BT, Christopherson K, Brahmi Z, Hromas R. Regulation of human natural killer cell migration and proliferation by the exodus subfamily of CC chemokines. Cellular Immunology. 199: 8-14. PMID 10675270 DOI: 10.1006/Cimm.1999.1601 |
0.682 |
|
| 2000 |
Hromas R, Cripe L, Hangoc G, Cooper S, Broxmeyer HE. The Exodus subfamily of CC chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors Blood. 95: 1506-1508. DOI: 10.1182/Blood.V95.4.1506.004K41_1506_1508 |
0.396 |
|
| 1999 |
Topcu Z, Mack DL, Hromas RA, Borden KL. The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control. Oncogene. 18: 7091-100. PMID 10597310 DOI: 10.1038/Sj.Onc.1203201 |
0.327 |
|
| 1999 |
Christopherson K, Brahmi Z, Hromas R. Regulation of naïve fetal T-cell migration by the chemokines Exodus-2 and Exodus-3. Immunology Letters. 69: 269-73. PMID 10482362 DOI: 10.1016/S0165-2478(99)00099-1 |
0.656 |
|
| 1999 |
Hromas R, Ye H, Spinella M, Dmitrovsky E, Xu D, Costa RH. Genesis, a Winged Helix transcriptional repressor, has embryonic expression limited to the neural crest, and stimulates proliferation in vitro in a neural development model. Cell and Tissue Research. 297: 371-82. PMID 10460485 DOI: 10.1007/S004410051365 |
0.371 |
|
| 1999 |
Broxmeyer HE, Kim CH, Cooper SH, Hangoc G, Hromas R, Pelus LM. Effects of CC, CXC, C, and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced chemotaxis of progenitors Annals of the New York Academy of Sciences. 872: 142-163. PMID 10372118 DOI: 10.1111/J.1749-6632.1999.Tb08460.X |
0.369 |
|
| 1999 |
Hromas R, Broxmeyer HE, Kim C, Christopherson K, Hou YH. Isolation of ALP, a novel divergent murine CC chemokine with a unique carboxy terminal extension. Biochemical and Biophysical Research Communications. 258: 737-40. PMID 10329455 DOI: 10.1006/Bbrc.1999.0507 |
0.63 |
|
| 1999 |
Hromas R, Broxmeyer HE, Kim C, Nakshatri H, Christopherson K, Azam M, Hou YH. Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells. Biochemical and Biophysical Research Communications. 255: 703-6. PMID 10049774 DOI: 10.1006/Bbrc.1999.0257 |
0.679 |
|
| 1998 |
Abonour R, Scott K, Kunkel L, Robertson M, Hromas R, Graves V, Lazaridis E, Cripe L, Gharpure V, Traycoff C, Mills B, Srour E, Cornetta K. Autologous transplantation of mobilized peripheral blood CD34+ cells selected by immunomagnetic procedures in patients with multiple myeloma. Bone Marrow Transplantation. 22: 957-963. PMID 9849692 DOI: 10.1038/Sj.Bmt.1701473 |
0.305 |
|
| 1998 |
Braun SE, Mantel C, Rosenthal M, Cooper S, Liu L, Robertson KA, Hromas R, Broxmeyer HE. A positive effect of p21cip1/waf1 in the colony formation from murine myeloid progenitor cells as assessed by retroviral-mediated gene transfer. Blood Cells, Molecules & Diseases. 24: 138-48. PMID 9628851 DOI: 10.1006/Bcmd.1998.0181 |
0.358 |
|
| 1998 |
Robertson KA, Hill DP, Kelley MR, Tritt R, Crum B, Van Epps S, Srour E, Rice S, Hromas R. The myeloid zinc finger gene (MZF-1) delays retinoic acid-induced apoptosis and differentiation in myeloid leukemia cells Leukemia. 12: 690-698. PMID 9593266 DOI: 10.1038/Sj.Leu.2401005 |
0.372 |
|
| 1998 |
Xu D, Yoder M, Sutton J, Hromas R. Forced expression of Genesis, a winged helix transcriptional repressor isolated from embryonic stem cells, blocks granulocytic differentiation of 32D myeloid cells. Leukemia. 12: 207-12. PMID 9519783 DOI: 10.1038/Sj.Leu.2400948 |
0.428 |
|
| 1998 |
Cornetta K, Gharpure V, Mills B, Hromas R, Abonour R, Broun ER, Traycoff CM, Hanna M, Wyman N, Danielson C, Gonin R, Kunkel LK, Oldham F, Srour EF. Rapid engraftment after allogeneic transplantation using CD34-enriched marrow cells. Bone Marrow Transplantation. 21: 65-71. PMID 9486497 DOI: 10.1038/Sj.Bmt.1701048 |
0.31 |
|
| 1997 |
Tenen DG, Hromas R, Licht JD, Zhang D. Transcription Factors, Normal Myeloid Development, and Leukemia Blood. 90: 489-519. DOI: 10.1182/Blood.V90.2.489.489_489_519 |
0.375 |
|
| 1997 |
Hromas R, Gray PW, Chantry D, Godiska R, Krathwohl M, Fife K, Bell GI, Takeda J, Aronica S, Gordon M, Cooper S, Broxmeyer HE, Klemsz MJ. Cloning and Characterization of Exodus, a Novel β-Chemokine Blood. 89: 3315-3322. DOI: 10.1182/Blood.V89.9.3315 |
0.386 |
|
| 1996 |
Sutton J, Costa R, Klug M, Field L, Xu D, Largaespada DA, Fletcher CF, Jenkins NA, Copeland NG, Klemsz M, Hromas R. Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells. The Journal of Biological Chemistry. 271: 23126-33. PMID 8798505 DOI: 10.1074/Jbc.271.38.23126 |
0.426 |
|
| 1996 |
Hromas R, Davis B, Rauscher FJ, Klemsz M, Tenen D, Hoffman S, Xu D, Morris JF. Hematopoietic transcriptional regulation by the myeloid zinc finger gene, MZF-1 Current Topics in Microbiology and Immunology. 211: 158-164. PMID 8585946 DOI: 10.1007/978-3-642-85232-9_16 |
0.334 |
|
| 1995 |
Hromas R, Klemsz M, Amaravadi L, Hufford T, Huang I, Desai A, Srour E, Bruno E, Hoffman R. Drosophila Forkhead homologues are expressed in CD34+/HLA-DR- primitive human hematopoietic progenitors. Leukemia & Lymphoma. 15: 439-44. PMID 7874001 DOI: 10.3109/10428199409049747 |
0.346 |
|
| 1995 |
Baumgartner S, Martin D, Chiquet-Ehrismann R, Sutton J, Desai A, Huang I, Kato K, Hromas R. The HEM proteins: A novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis Journal of Molecular Biology. 251: 41-49. PMID 7643388 DOI: 10.1006/Jmbi.1995.0414 |
0.338 |
|
| 1995 |
Hromas R, Costa R. The hepatocyte nuclear factor-3/forkhead transcription regulatory family in development, inflammation, and neoplasia Critical Reviews in Oncology and Hematology. 20: 129-140. PMID 7576194 DOI: 10.1016/1040-8428(94)00151-I |
0.362 |
|
| 1995 |
Morris JF, Rauscher FJ, Davis B, Klemsz M, Xu D, Tenen D, Hromas R. The myeloid zinc finger gene, MZF-1, regulates the CD34 promoter in vitro Blood. 86: 3640-3647. DOI: 10.1182/Blood.V86.10.3640.Bloodjournal86103640 |
0.389 |
|
| 1994 |
Klemsz M, Hromas R, Raskind W, Bruno E, Hoffman R. PE-1, a novel ETS oncogene family member, localizes to chromosome 1q21-q23. Genomics. 20: 291-4. PMID 8020980 DOI: 10.1006/Geno.1994.1169 |
0.31 |
|
| 1993 |
Hromas R, May W, Denny C, Raskind W, Moore J, Maki RA, Beck E, Klemsz MJ. Human FLI-1 localizes to chromosome 11Q24 and has an aberrant transcript in neuroepithelioma. Biochimica Et Biophysica Acta. 1172: 155-8. PMID 8439553 DOI: 10.1016/0167-4781(93)90283-J |
0.321 |
|
| 1993 |
Hromas R, Radich J, Collins S. PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells. Biochemical and Biophysical Research Communications. 195: 976-83. PMID 8103988 DOI: 10.1006/Bbrc.1993.2140 |
0.34 |
|
| 1993 |
Moore J, Boswell S, Hoffman R, Burgess G, Hromas R. Mutant H-ras over-expression inhibits a random apoptotic nuclease in myeloid leukemia cells. Leukemia Research. 17: 703-9. PMID 7689129 DOI: 10.1016/0145-2126(93)90078-Y |
0.315 |
|
| 1993 |
Hromas R, Orazi A, Neiman R, Maki R, Van Beveran C, Moore J, Klemsz M. Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1 Blood. 82: 2998-3004. DOI: 10.1182/Blood.V82.10.2998.Bloodjournal82102998 |
0.39 |
|
| 1993 |
Hromas R, Moore J, Johnston T, Socha C, Klemsz M. Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells Blood. 81: 2854-2859. DOI: 10.1182/Blood.V81.11.2854.2854 |
0.328 |
|
| 1992 |
Hromas R, Zon L, Friedman AD. Hematopoietic transcription regulators and the origins of leukemia. Critical Reviews in Oncology/Hematology. 12: 167-90. PMID 1590941 DOI: 10.1016/1040-8428(92)90088-8 |
0.302 |
|
| 1991 |
Hromas R, Collins S, Raskind W, Deaven L, Kaushansky K. Hem-1, a potential membrane protein, with expression restricted to blood cells Bba - Gene Structure and Expression. 1090: 241-244. PMID 1932118 DOI: 10.1016/0167-4781(91)90109-Y |
0.301 |
|
| 1991 |
Radford JJ, Chen E, Hromas R, Ginder G. Cell-type specificity of interferon-gamma-mediated HLA class I gene transcription in human hematopoietic tumor cells Blood. 77: 2008-2015. DOI: 10.1182/Blood.V77.9.2008.Bloodjournal7792008 |
0.34 |
|
| 1990 |
Nelms K, Hromas R, Van Ness B. Identification of a second inducible DNA-protein interaction in the kappa immunoglobulin enhancer. Nucleic Acids Research. 18: 1037-43. PMID 2107525 DOI: 10.1093/Nar/18.4.1037 |
0.35 |
|
| 1988 |
Hromas R, Pauli U, Marcuzzi A, Lafrenz D, Nick H, Stein J, Stein G, Van Ness B. Inducible DNA-protein interactions of the murine kappa immunoglobulin enhancer in intact cells: comparison with in vitro interactions. Nucleic Acids Research. 16: 953-67. PMID 2830597 DOI: 10.1093/Nar/16.3.953 |
0.403 |
|
| 1986 |
Hromas R, Van Ness B. Nuclear factors bind to regulatory regions of the mouse kappa immunoglobulin gene. Nucleic Acids Research. 14: 4837-48. PMID 3088544 DOI: 10.1093/Nar/14.12.4837 |
0.306 |
|
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