Steve C. Schultz, Ph.D. - Related publications

Chemistry and Biochemistry University of Colorado, Boulder, Boulder, CO, United States 
telomeres, telomerase
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Zaug AJ, Lim CJ, Olson CL, Carilli MT, Goodrich KJ, Wuttke DS, Cech TR. CST does not evict elongating telomerase but prevents initiation by ssDNA binding. Nucleic Acids Research. PMID 34718732 DOI: 10.1093/nar/gkab942   
2021 Ge J, Qiu X. Expression, purification, characterization of DNA binding activity and crystallization of a putative type II DNA Cytosine-5-methyltransferase from Microcystis aeruginosa. Protein Expression and Purification. 189: 105988. PMID 34634480 DOI: 10.1016/j.pep.2021.105988   
2021 Sarkar R, Petrushenko ZM, Dawson DS, Rybenkov VV. Ycs4 Subunit of Condensin Binds DNA and Modulates the Enzyme Turnover. Biochemistry. PMID 34723504 DOI: 10.1021/acs.biochem.1c00473   
2021 Hu J, Bai YS, Zheng LL, Jia NX, Yu DJ, Zhang G. Protein-DNA Binding Residue Prediction via Bagging Strategy and Sequence-based Cube-Format Feature. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 34714748 DOI: 10.1109/TCBB.2021.3123828   
2021 Singh JK, Smith R, Rother MB, de Groot AJL, Wiegant WW, Vreeken K, D'Augustin O, Kim RQ, Qian H, Krawczyk PM, González-Prieto R, Vertegaal ACO, Lamers M, Huet S, van Attikum H. Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining. Nature Communications. 12: 6560. PMID 34772923 DOI: 10.1038/s41467-021-26691-0   
2021 Padmanabhan S, Sanyal K, Dubey D. Identification and analysis of the origin recognition complex in the human fungal pathogen . Micropublication Biology. 2021. PMID 34568775 DOI: 10.17912/micropub.biology.000465   
2021 Zhang X, Zheng Q. How DNA affects the hyperthermophilic protein Ape10b2 for oligomerization: an investigation using multiple short molecular dynamics simulations. Physical Chemistry Chemical Physics : Pccp. 23: 25841-25849. PMID 34763347 DOI: 10.1039/d1cp04341b   
2021 Okafor IC, Choi J, Ha T. Single Molecule Methods for studying CRISPR Cas9-Induced DNA Unwinding. Methods (San Diego, Calif.). PMID 34767923 DOI: 10.1016/j.ymeth.2021.11.003   
2021 Lyu J, Yang M, Zhang C, Luo Y, Qin T, Su Z, Huang Z. DNA nanostructures directed by RNA clamps. Nanoscale. PMID 34825903 DOI: 10.1039/d1nr03919a   
2021 Zhang J, Fakharzadeh A, Pan F, Roland C, Sagui C. Construction of DNA/RNA Triplex Helices Based on GAA/TTC Trinucleotide Repeats. Bio-Protocol. 11: e4155. PMID 34692905 DOI: 10.21769/BioProtoc.4155   
2021 Saecker RM, Chen J, Chiu CE, Malone B, Sotiris J, Ebrahim M, Yen LY, Eng ET, Darst SA. Structural origins of RNA polymerase open promoter complex stability. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34599106 DOI: 10.1073/pnas.2112877118   
2021 Lee H, Cho H, Kim J, Lee S, Yoo J, Park D, Lee G. RNase H is an exo- and endoribonuclease with asymmetric directionality, depending on the binding mode to the structural variants of RNA:DNA hybrids. Nucleic Acids Research. PMID 34788459 DOI: 10.1093/nar/gkab1064   
2021 Pan J, Lian K, Sarre A, Leiros HS, Williamson A. Bacteriophage origin of some minimal ATP-dependent DNA ligases: a new structure from Burkholderia pseudomallei with striking similarity to Chlorella virus ligase. Scientific Reports. 11: 18693. PMID 34548548 DOI: 10.1038/s41598-021-98155-w   
2021 Liu J, Mei Q, Nimer S, Fitzgerald DM, Rosenberg SM. Genomic mapping of DNA-repair reaction intermediates in living cells with engineered DNA structure-trap proteins. Methods in Enzymology. 661: 155-181. PMID 34776211 DOI: 10.1016/bs.mie.2021.09.015   
2021 Neetu N, Katiki M, Mahto JK, Sharma M, Narayanan A, Maity S, Tomar S, Ambatipudi K, Sharma AK, Yernool D, Kumar P. Deciphering the enigma of missing DNA binding domain of LacI family transcription factors. Archives of Biochemistry and Biophysics. 713: 109060. PMID 34666048 DOI: 10.1016/   
2021 Dickerhoff J, Warnecke KR, Wang K, Deng N, Yang D. Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA. International Journal of Molecular Sciences. 22. PMID 34639142 DOI: 10.3390/ijms221910801   
2021 Liu H, Hong F, Smith F, Goertz J, Ouldridge T, Stevens MM, Yan H, Šulc P. Kinetics of RNA and RNA:DNA Hybrid Strand Displacement. Acs Synthetic Biology. PMID 34752075 DOI: 10.1021/acssynbio.1c00336   
2021 Boucher D, Kariawasam R, Burgess J, Gimenez A, Ocampo TE, Ferguson B, Naqi A, Walker GJ, Bolderson E, Gamsjaeger R, O'Byrne KJ, Cubeddu L, Khanna KK, Richard DJ. hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage. Scientific Reports. 11: 20256. PMID 34642383 DOI: 10.1038/s41598-021-99355-0   
2021 López-Vidriero I, Godoy M, Grau J, Peñuelas M, Solano R, Franco-Zorrilla JM. DNA features beyond the transcription factor binding site specify target recognition by plant MYC2-related bHLH proteins. Plant Communications. 2: 100232. PMID 34778747 DOI: 10.1016/j.xplc.2021.100232   
2021 Chen W, Lu W, Wolynes PG, Komives EA. Single-molecule conformational dynamics of a transcription factor reveals a continuum of binding modes controlling association and dissociation. Nucleic Acids Research. PMID 34614173 DOI: 10.1093/nar/gkab874   
2021 Perera HM, Trakselis MA. Determining translocation orientations of nucleic acid helicases. Methods (San Diego, Calif.). PMID 34758393 DOI: 10.1016/j.ymeth.2021.11.001   
2021 Javed A, Major B, Stead JA, Sanders CM, Orlova EV. Unwinding of a DNA replication fork by a hexameric viral helicase. Nature Communications. 12: 5535. PMID 34545080 DOI: 10.1038/s41467-021-25843-6   
2021 Cappadocia L, Kochańczyk T, Lima CD. DNA asymmetry promotes SUMO modification of the single-stranded DNA-binding protein RPA. The Embo Journal. e103787. PMID 34585421 DOI: 10.15252/embj.2019103787   
2021 Köhn B, Schwarz P, Wittung-Stafshede P, Kovermann M. Impact of crowded environments on binding between protein and single-stranded DNA. Scientific Reports. 11: 17682. PMID 34480058 DOI: 10.1038/s41598-021-97219-1   
2021 Babu K, Kathiresan V, Kumari P, Newsom S, Parameshwaran HP, Chen X, Liu J, Qin PZ, Rajan R. Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence. Biochemistry. PMID 34757726 DOI: 10.1021/acs.biochem.1c00354   
2021 Altun A, Garcia-Ratés M, Neese F, Bistoni G. Unveiling the complex pattern of intermolecular interactions responsible for the stability of the DNA duplex. Chemical Science. 12: 12785-12793. PMID 34703565 DOI: 10.1039/d1sc03868k   
2021 Hoffmann T, Mrusek D, Bedrunka P, Burchert F, Mais CN, Kearns DB, Altegoer F, Bremer E, Bange G. Structural and functional characterization of the bacterial biofilm activator RemA. Nature Communications. 12: 5707. PMID 34588455 DOI: 10.1038/s41467-021-26005-4   
2021 Day M, Oliver AW, Pearl LH. Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1. Dna Repair. 108: 103232. PMID 34678589 DOI: 10.1016/j.dnarep.2021.103232   
2021 Bürmann F, Funke LFH, Chin JW, Löwe J. Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Molecular Cell. PMID 34739874 DOI: 10.1016/j.molcel.2021.10.011   
2021 Paulsen T, Malapati P, Shibata Y, Wilson B, Eki R, Benamar M, Abbas T, Dutta A. MicroDNA levels are dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA damage. Nucleic Acids Research. 49: 11787-11799. PMID 34718766 DOI: 10.1093/nar/gkab984   
2021 Chen S, Lees-Miller JP, He Y, Lees-Miller SP. Structural insights into the role of DNA-PK as a master regulator in NHEJ. Genome Instability & Disease. 2: 195-210. PMID 34723130 DOI: 10.1007/s42764-021-00047-w   
2021 Qutbuddin Y, Krohn JH, Brüggenthies GA, Stein J, Gavrilovic S, Stehr F, Schwille P. Design Features to Accelerate the Higher-Order Assembly of DNA Origami on Membranes. The Journal of Physical Chemistry. B. PMID 34818013 DOI: 10.1021/acs.jpcb.1c07694   
2021 Fogg JM, Judge AK, Stricker E, Chan HL, Zechiedrich L. Supercoiling and looping promote DNA base accessibility and coordination among distant sites. Nature Communications. 12: 5683. PMID 34584096 DOI: 10.1038/s41467-021-25936-2   
2021 Miller J, Peters JP. Examining the Effects of Netropsin on the Curvature of DNA A-Tracts Using Electrophoresis. Molecules (Basel, Switzerland). 26. PMID 34641414 DOI: 10.3390/molecules26195871   
2021 Ogunleye AJ, Romanova E, Medvedeva YA. Genome-wide regulation of CpG methylation by ecCEBPα in acute myeloid leukemia. F1000research. 10: 204. PMID 34557292 DOI: 10.12688/f1000research.28146.2   
2021 Go Y, Ahn HB, Kim BS, Lee AR, Oh KI, Lee JH. Conformational exchange of the Zα domain of human RNA editing enzyme ADAR1 studied by NMR spectroscopy. Biochemical and Biophysical Research Communications. 580: 63-66. PMID 34624571 DOI: 10.1016/j.bbrc.2021.09.084   
2021 Lancey C, Tehseen M, Bakshi S, Percival M, Takahashi M, Sobhy MA, Raducanu VS, Blair K, Muskett FW, Ragan TJ, Crehuet R, Hamdan SM, De Biasio A. Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA. Nature Communications. 12: 6095. PMID 34667155 DOI: 10.1038/s41467-021-26251-6   
2021 Dougherty AC, Hawaz MG, Hoang KG, Trac J, Keck JM, Ayes C, Deweese JE. Exploration of the Role of the C-Terminal Domain of Human DNA Topoisomerase IIα in Catalytic Activity. Acs Omega. 6: 25892-25903. PMID 34660952 DOI: 10.1021/acsomega.1c02083   
2021 Nitiss JL, Kiianitsa K, Sun Y, Nitiss KC, Maizels N. Topoisomerase Assays. Current Protocols. 1: e250. PMID 34606690 DOI: 10.1002/cpz1.250   
2021 Kaur P, Pan H, Longley MJ, Copeland WC, Wang H. Using Atomic Force Microscopy to Study the Real Time Dynamics of DNA Unwinding by Mitochondrial Twinkle Helicase. Bio-Protocol. 11: e4139. PMID 34604445 DOI: 10.21769/BioProtoc.4139   
2021 Liu W, Li J, Xu Y, Yin D, Zhu X, Fu H, Su X, Guo X. Complete Mapping of DNA-Protein Interactions at the Single-Molecule Level. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2101383. PMID 34609790 DOI: 10.1002/advs.202101383   
2021 Shi H, Kimsey IJ, Gu S, Liu HF, Pham U, Schumacher MA, Al-Hashimi HM. Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA. Nucleic Acids Research. PMID 34792150 DOI: 10.1093/nar/gkab936   
2021 Sielemann J, Wulf D, Schmidt R, Bräutigam A. Local DNA shape is a general principle of transcription factor binding specificity in Arabidopsis thaliana. Nature Communications. 12: 6549. PMID 34772949 DOI: 10.1038/s41467-021-26819-2   
2021 Liu B, Li S, Liu Y, Chen H, Hu Z, Wang Z, Zhao Y, Zhang L, Ma B, Wang H, Matthews S, Wang Y, Zhang K. Bacteriophage Twort protein Gp168 is a β-clamp inhibitor by occupying the DNA sliding channel. Nucleic Acids Research. PMID 34614154 DOI: 10.1093/nar/gkab875   
2021 Nickoloff JA, Sharma N, Taylor L, Allen SJ, Hromas R. The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination. Frontiers in Genetics. 12: 748033. PMID 34646312 DOI: 10.3389/fgene.2021.748033   
2021 Chen Y, Li Y, Xiong J, Lan B, Wang X, Liu J, Lin J, Fei Z, Zheng X, Chen C. Role of PRKDC in cancer initiation, progression, and treatment. Cancer Cell International. 21: 563. PMID 34702253 DOI: 10.1186/s12935-021-02229-8   
2021 Liu Y, Lan W, Wang C, Cao C. Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance. Protein Science : a Publication of the Protein Society. PMID 34792260 DOI: 10.1002/pro.4242   
2021 Grimwade JE, Leonard AC. Blocking, Bending, and Binding: Regulation of Initiation of Chromosome Replication During the Cell Cycle by Transcriptional Modulators That Interact With Origin DNA. Frontiers in Microbiology. 12: 732270. PMID 34616385 DOI: 10.3389/fmicb.2021.732270   
2021 Khamari L, Pramanik S, Shekhar S, Mahato P, Mukherjee S. Preferential Binding of Epirubicin Hydrochloride with Single Nucleotide Mismatched DNA and Subsequent Sequestration by a Mixed Micelle. The Journal of Physical Chemistry. B. PMID 34652157 DOI: 10.1021/acs.jpcb.1c06944   
2021 Strutzenberg TS, Zhu Y, Novick SJ, Garcia-Ordonez RD, Doebelin C, He Y, Ra Chang M, Kamenecka TM, Edwards DP, Griffin PR. Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement. Journal of Molecular Biology. 167258. PMID 34547329 DOI: 10.1016/j.jmb.2021.167258