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Jon C. Clardy, Ph.D. - Publications

Affiliations: 
1970-1977 Chemistry Iowa State University, Ames, IA, United States 
 1978-2008 Chemistry Cornell University, Ithaca, NY, United States 
 2009- Chemistry Harvard University, Cambridge, MA, United States 
Area:
natural products
Website:
https://www.broadinstitute.org/bios/jon-clardy
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Year Citation  Score
2023 Seyedsayamdost MR, Clardy J. Discovering functional small molecules in the gut microbiome. Current Opinion in Chemical Biology. 75: 102309. PMID 37163788 DOI: 10.1016/j.cbpa.2023.102309  0.543
2023 Kwon J, Bae M, Szamosvári D, Cassilly CD, Bolze AS, Jackson DR, Xavier RJ, Clardy J. Produces a pH-Responsive Lipid Immunogen. Journal of the American Chemical Society. PMID 36952265 DOI: 10.1021/jacs.3c00250  0.731
2022 Szamosvári D, Bae M, Bang S, Tusi BK, Cassilly CD, Park SM, Graham DB, Xavier RJ, Clardy J. Lyme Disease, , and Lipid Immunogens. Journal of the American Chemical Society. 144: 2474-2478. PMID 35129341 DOI: 10.1021/jacs.1c12202  0.72
2021 Henke MT, Brown EM, Cassilly CD, Vlamakis H, Xavier RJ, Clardy J. Capsular polysaccharide correlates with immune response to the human gut microbe . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33972416 DOI: 10.1073/pnas.2007595118  0.765
2020 Bowden GD, Reis PM, Rogers MB, Bone Relat RM, Brayton KA, Wilson SK, Di Genova BM, Knoll LJ, Nepveux V FJ, Tai AK, Ramadhar TR, Clardy J, O'Connor RM. A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E. International Journal For Parasitology. Drugs and Drug Resistance. 14: 1-7. PMID 32738587 DOI: 10.1016/J.Ijpddr.2020.07.003  0.726
2020 O'Connor RM, Nepveux V FJ, Abenoja J, Bowden G, Reis P, Beaushaw J, Bone Relat RM, Driskell I, Gimenez F, Riggs MW, Schaefer DA, Schmidt EW, Lin Z, Distel DL, Clardy J, et al. A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity. Plos Pathogens. 16: e1008600. PMID 32453775 DOI: 10.1371/Journal.Ppat.1008600  0.734
2019 Helfrich EJN, Lin GM, Voigt CA, Clardy J. Bacterial terpene biosynthesis: challenges and opportunities for pathway engineering. Beilstein Journal of Organic Chemistry. 15: 2889-2906. PMID 31839835 DOI: 10.3762/Bjoc.15.283  0.31
2019 Henke MT, Clardy J. Molecular messages in human microbiota. Science (New York, N.Y.). 366: 1309-1310. PMID 31831655 DOI: 10.1126/Science.Aaz4164  0.759
2019 Mevers E, Saurí J, Helfrich EJN, Henke M, Barns KJ, Bugni TS, Andes DR, Currie CR, Clardy J. Pyonitrins A-D: Chimeric natural products produced by Pseudomonas protegens. Journal of the American Chemical Society. PMID 31600443 DOI: 10.1021/Jacs.9B09739  0.809
2019 Henke MT, Kenny DJ, Cassilly CD, Vlamakis H, Xavier RJ, Clardy J. , a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide. Proceedings of the National Academy of Sciences of the United States of America. PMID 31182571 DOI: 10.1073/Pnas.1904099116  0.769
2019 Cao S, Clardy J. New naphthoquinones and a new δ-lactone produced by endophytic fungi from Costa Rica. Tetrahedron Letters. 52: 2206-2208. PMID 21643520 DOI: 10.1016/J.Tetlet.2010.11.159  0.323
2018 Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, ... ... Clardy J, et al. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741. PMID 30648156 DOI: 10.1021/Acscentsci.8B00747  0.756
2018 Liao J, Xu G, Mevers EE, Clardy J, Watnick PI. A high-throughput, whole cell assay to identify compounds active against carbapenem-resistant Klebsiella pneumoniae. Plos One. 13: e0209389. PMID 30576339 DOI: 10.1371/Journal.Pone.0209389  0.321
2018 Brown A, Clardy J. Tiny crystals have big potential for determining structures of small molecules. Nature. 564: 348-349. PMID 30559356 DOI: 10.1038/D41586-018-07756-5  0.305
2018 Strandwitz P, Kim KH, Terekhova D, Liu JK, Sharma A, Levering J, McDonald D, Dietrich D, Ramadhar TR, Lekbua A, Mroue N, Liston C, Stewart EJ, Dubin MJ, Zengler K, ... ... Clardy J, et al. GABA-modulating bacteria of the human gut microbiota. Nature Microbiology. PMID 30531975 DOI: 10.1038/S41564-018-0307-3  0.765
2018 Li H, Sosa-Calvo J, Horn HA, Pupo MT, Clardy J, Rabeling C, Schultz TR, Currie CR. Convergent evolution of complex structures for ant-bacterial defensive symbiosis in fungus-farming ants. Proceedings of the National Academy of Sciences of the United States of America. PMID 30282739 DOI: 10.1073/Pnas.1809332115  0.312
2018 Pishchany G, Mevers E, Ndousse-Fetter S, Horvath DJ, Paludo CR, Silva-Junior EA, Koren S, Skaar EP, Clardy J, Kolter R. Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen. Proceedings of the National Academy of Sciences of the United States of America. PMID 30228116 DOI: 10.1073/Pnas.1807613115  0.315
2018 Ganley J, Carr G, Ioerger T, Sacchettini J, Clardy J, Derbyshire E. Discovery of antimicrobial lipodepsipeptides produced by a Serratia sp. within mosquito microbiomes. Chembiochem : a European Journal of Chemical Biology. PMID 29700993 DOI: 10.1002/Cbic.201800124  0.648
2018 Böttcher T, Szamosvári D, Clardy J. A repeating sulfated galactan motif resuscitates dormant . Applied and Environmental Microbiology. PMID 29678921 DOI: 10.1128/Aem.00745-18  0.781
2018 Puri AW, Mevers E, Ramadhar TR, Petras D, Liu D, Piel J, Dorrestein PC, Greenberg P, Lidstrom ME, Clardy J. Tundrenone: An Atypical Secondary Metabolite from Bacteria with Highly Restricted Primary Metabolism. Journal of the American Chemical Society. PMID 29361220 DOI: 10.1021/Jacs.7B12240  0.736
2018 Ganley JG, Carr G, Ioerger TR, Sacchettini JC, Clardy J, Derbyshire ER. Front Cover: Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes (ChemBioChem 15/2018) Chembiochem. 19: 1570-1570. DOI: 10.1002/Cbic.201800362  0.63
2017 Ramadhar TR, Zheng SL, Chen YS, Clardy J. The Crystalline Sponge Method: A Solvent-Based Strategy to Facilitate Noncovalent Ordered Trapping of Solid and Liquid Organic Compounds. Crystengcomm. 19: 4528-4534. PMID 29225511 DOI: 10.1039/C7Ce00885F  0.743
2017 Mevers E, Chouvenc T, Su NY, Clardy J. Chemical Interaction among Termite-Associated Microbes. Journal of Chemical Ecology. PMID 29134406 DOI: 10.1007/S10886-017-0900-6  0.307
2017 Guo H, Rischer M, Sperfeld M, Weigel C, Menzel KD, Clardy J, Beemelmanns C. Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata. Bioorganic & Medicinal Chemistry. PMID 28893599 DOI: 10.1016/J.Bmc.2017.06.053  0.61
2017 Woznica A, Gerdt JP, Hulett RE, Clardy J, King N. Mating in the Closest Living Relatives of Animals Is Induced by a Bacterial Chondroitinase. Cell. PMID 28867285 DOI: 10.1016/J.Cell.2017.08.005  0.502
2017 Wyche TP, Ruzzini AC, Schwab L, Currie CR, Clardy J. Tryptorubin A, a polycyclic peptide from a fungus-derived Streptomycete. Journal of the American Chemical Society. PMID 28853867 DOI: 10.1021/Jacs.7B06176  0.351
2017 Van Arnam EB, Currie CR, Clardy J. Defense contracts: molecular protection in insect-microbe symbioses. Chemical Society Reviews. PMID 28745342 DOI: 10.1039/C7Cs00340D  0.302
2017 Liu Y, Saurí J, Mevers E, Peczuh MW, Hiemstra H, Clardy J, Martin GE, Williamson RT. Unequivocal determination of complex molecular structures using anisotropic NMR measurements. Science (New York, N.Y.). 356. PMID 28385960 DOI: 10.1126/Science.Aam5349  0.331
2017 Wyche TP, Ruzzini AC, Beemelmanns C, Kim KH, Klassen JL, Cao S, Poulsen M, Bugni TS, Currie CR, Clardy J. Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides. Organic Letters. PMID 28326787 DOI: 10.1021/Acs.Orglett.7B00545  0.611
2017 Beemelmanns C, Ramadhar TR, Kim KH, Klassen JL, Cao S, Wyche TP, Hou Y, Poulsen M, Bugni TS, Currie CR, Clardy J. Macrotermycins A-D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39. Organic Letters. PMID 28207275 DOI: 10.1021/Acs.Orglett.6B03831  0.783
2016 Garcia DM, Dietrich D, Clardy J, Jarosz DF. A common bacterial metabolite elicits prion-based bypass of glucose repression. Elife. 5. PMID 27906649 DOI: 10.7554/Elife.17978  0.538
2016 Van Arnam EB, Ruzzini AC, Sit CS, Horn H, Pinto-Tomás AA, Currie CR, Clardy J. Selvamicin, an atypical antifungal polyene from two alternative genomic contexts. Proceedings of the National Academy of Sciences of the United States of America. PMID 27803316 DOI: 10.1073/Pnas.1613285113  0.714
2016 Mevers E, Saurí J, Liu Y, Moser A, Ramadhar TR, Varlan M, Williamson RT, Martin GE, Clardy J. Homodimericin A: a complex hexacyclic fungal metabolite. Journal of the American Chemical Society. PMID 27608853 DOI: 10.1021/Jacs.6B07588  0.739
2016 Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci NM, Bittker JA, Corey V, Clarke D, Derbyshire ER, Dornan G, Duffy S, Eckley S, ... ... Clardy JC, et al. Diversity-oriented synthesis yields novel multistage antimalarial inhibitors. Nature. PMID 27602946 DOI: 10.1038/Nature19804  0.654
2016 Lee SR, Beemelmanns C, Tsuma LM, Clardy J, Cao S, Kim KH. A New Diketopiperazine, Cyclo(D-trans-Hyp-L-Leu) from a Kenyan Bacterium Bacillus licheniformis LB 8CT. Natural Product Communications. 11: 461-3. PMID 27396193 DOI: 10.1177/1934578X1601100410  0.585
2016 Woznica A, Cantley AM, Beemelmanns C, Freinkman E, Clardy J, King N. Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates. Proceedings of the National Academy of Sciences of the United States of America. PMID 27354530 DOI: 10.1073/Pnas.1605015113  0.68
2016 Lear S, Munshi T, Hudson AS, Hatton C, Clardy J, Mosely JA, Bull TJ, Sit CS, Cobb SL. Total chemical synthesis of lassomycin and lassomycin-amide. Organic & Biomolecular Chemistry. 14: 4534-41. PMID 27101411 DOI: 10.1039/C6Ob00631K  0.698
2016 Lee S, Tamayo-Castillo G, Pang C, Clardy J, Cao S, Kim KH. Diketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465A. Bioorganic & Medicinal Chemistry Letters. PMID 27080179 DOI: 10.1016/J.Bmcl.2016.03.115  0.315
2016 Cantley AM, Woznica A, Beemelmanns C, King N, Clardy J. Isolation and Synthesis of a Bacterially Produced Inhibitor of Rosette Development in Choanoflagellates. Journal of the American Chemical Society. PMID 26998963 DOI: 10.1021/Jacs.6B01190  0.701
2016 Böttcher T, Elliott HL, Clardy J. Dynamics of Snake-like Swarming Behavior of Vibrio alginolyticus. Biophysical Journal. 110: 981-92. PMID 26910435 DOI: 10.1016/J.Bpj.2015.12.037  0.545
2016 Rischer M, Klassen JL, Wolf T, Guo H, Shelest E, Clardy J, Beemelmanns C. Draft Genome Sequence of Shewanella sp. Strain P1-14-1, a Bacterial Inducer of Settlement and Morphogenesis in Larvae of the Marine Hydroid Hydractinia echinata. Genome Announcements. 4. PMID 26893410 DOI: 10.1128/Genomea.00003-16  0.576
2016 Böttcher T, Elliott HL, Clardy J. Dynamics of snake-like swarming behavior of vibrio alginolyticus Biophysical Journal. 110: 981-992. DOI: 10.1016/j.bpj.2015.12.037  0.442
2016 Lee SR, Clardy J, Senger DR, Cao S, Kim KH. Iridoid and phenylethanoid glycosides from the aerial part of Barleria lupulina Revista Brasileira De Farmacognosia. 26: 281-284. DOI: 10.1016/J.Bjp.2016.01.002  0.323
2015 Klassen JL, Wolf T, Rischer M, Guo H, Shelest E, Clardy J, Beemelmanns C. Draft Genome Sequences of Six Pseudoalteromonas Strains, P1-7a, P1-9, P1-13-1a, P1-16-1b, P1-25, and P1-26, Which Induce Larval Settlement and Metamorphosis in Hydractinia echinata. Genome Announcements. 3. PMID 26679587 DOI: 10.1128/Genomea.01477-15  0.548
2015 Raphemot R, Lafuente-Monasterio MJ, Gamo-Benito FJ, Clardy J, Derbyshire ER. Discovery of Dual Stage Malaria Inhibitors with New Targets. Antimicrobial Agents and Chemotherapy. PMID 26666931 DOI: 10.1128/Aac.02110-15  0.629
2015 Klassen JL, Rischer M, Wolf T, Guo H, Shelest E, Clardy J, Beemelmanns C. Genome Sequences of Three Pseudoalteromonas Strains (P1-8, P1-11, and P1-30), Isolated from the Marine Hydroid Hydractinia echinata. Genome Announcements. 3. PMID 26659670 DOI: 10.1128/Genomea.01380-15  0.569
2015 Van Arnam EB, Ruzzini AC, Sit CS, Currie CR, Clardy J. A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense. Journal of the American Chemical Society. PMID 26535611 DOI: 10.1021/Jacs.5B09794  0.716
2015 Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, et al. Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts. Journal of Natural Products. PMID 26465675 DOI: 10.1021/Acs.Jnatprod.5B00489  0.351
2015 Sit CS, Ruzzini AC, Van Arnam EB, Ramadhar TR, Currie CR, Clardy J. Variable genetic architectures produce virtually identical molecules in bacterial symbionts of fungus-growing ants. Proceedings of the National Academy of Sciences of the United States of America. 112: 13150-4. PMID 26438860 DOI: 10.1073/Pnas.1515348112  0.797
2015 Hiraki M, Hwang SY, Cao S, Ramadhar TR, Byun S, Yoon KW, Lee JH, Chu K, Gurkar AU, Kolev V, Zhang J, Namba T, Murphy ME, Newman DJ, Mandinova A, ... Clardy J, et al. Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis. Chemistry & Biology. PMID 26320861 DOI: 10.1016/J.Chembiol.2015.07.016  0.71
2015 Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Clardy J, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890  0.723
2015 Byun S, Lim S, Mun JY, Kim KH, Ramadhar TR, Farrand L, Shin SH, Thimmegowda NR, Lee HJ, Frank DA, Clardy J, Lee SW, Lee KW. Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways. The Journal of Biological Chemistry. PMID 26242912 DOI: 10.1074/Jbc.M115.662445  0.714
2015 Kim KH, Clardy J, Senger D, Cao S. Chakyunglupulins A and B, two novel 4,8,8-trimethylcyclooct-2-enone derivatives from Barleria lupulina. Tetrahedron Letters. 56: 2732-2734. PMID 26240452 DOI: 10.1016/J.Tetlet.2015.04.023  0.332
2015 Ramadhar TR, Zheng SL, Chen YS, Clardy J. The crystalline sponge method: MOF terminal ligand effects. Chemical Communications (Cambridge, England). 51: 11252-5. PMID 26081991 DOI: 10.1039/C5Cc03840E  0.705
2015 Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, ... ... Clardy J, et al. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Science Translational Medicine. 7: 288ra77. PMID 25995223 DOI: 10.1126/Scitranslmed.Aaa3575  0.616
2015 Kim KH, Beemelmanns C, Clardy J, Cao S. A new antibacterial octaketide and cytotoxic phenylethanoid glycosides from Pogostemon cablin (Blanco) Benth. Bioorganic & Medicinal Chemistry Letters. 25: 2834-6. PMID 25981688 DOI: 10.1016/J.Bmcl.2015.04.094  0.61
2015 Kim KH, Park YJ, Chung KH, Yip ML, Clardy J, Senger D, Cao S. Iridoid glycosides from Barleria lupulina. Journal of Natural Products. 78: 320-4. PMID 25611215 DOI: 10.1021/Np500791A  0.305
2015 Ramadhar TR, Zheng SL, Chen YS, Clardy J. Analysis of rapidly synthesized guest-filled porous complexes with synchrotron radiation: practical guidelines for the crystalline sponge method. Acta Crystallographica. Section a, Foundations and Advances. 71: 46-58. PMID 25537388 DOI: 10.1107/S2053273314019573  0.722
2015 Wyche T, Ruzzini A, Schwab L, Currie C, Clardy J. Structure elucidation of two novel peptides from a mushroom-derived Streptomyces sp. Planta Medica. 81. DOI: 10.1055/S-0035-1556393  0.348
2014 Kim KH, Ramadhar TR, Beemelmanns C, Cao S, Poulsen M, Currie CR, Clardy J. Natalamycin A, an Ansamycin from a Termite-Associated Streptomyces sp. Chemical Science (Royal Society of Chemistry : 2010). 5: 4333-4338. PMID 25386334 DOI: 10.1039/C4Sc01136H  0.808
2014 Seyedsayamdost MR, Wang R, Kolter R, Clardy J. Hybrid biosynthesis of roseobacticides from algal and bacterial precursor molecules. Journal of the American Chemical Society. 136: 15150-3. PMID 25295497 DOI: 10.1021/Ja508782Y  0.783
2014 Donia MS, Cimermancic P, Schulze CJ, Wieland Brown LC, Martin J, Mitreva M, Clardy J, Linington RG, Fischbach MA. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 158: 1402-14. PMID 25215495 DOI: 10.1016/J.Cell.2014.08.032  0.307
2014 Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J. Chemical interrogation of the malaria kinome. Chembiochem : a European Journal of Chemical Biology. 15: 1920-30. PMID 25111632 DOI: 10.1002/Cbic.201400025  0.614
2014 Beemelmanns C, Woznica A, Alegado RA, Cantley AM, King N, Clardy J. Synthesis of the rosette-inducing factor RIF-1 and analogs. Journal of the American Chemical Society. 136: 10210-3. PMID 24983513 DOI: 10.1021/Ja5046692  0.692
2014 Book AJ, Lewin GR, McDonald BR, Takasuka TE, Doering DT, Adams AS, Blodgett JA, Clardy J, Raffa KF, Fox BG, Currie CR. Cellulolytic Streptomyces strains associated with herbivorous insects share a phylogenetically linked capacity to degrade lignocellulose. Applied and Environmental Microbiology. 80: 4692-701. PMID 24837391 DOI: 10.1128/Aem.01133-14  0.778
2014 Seyedsayamdost MR, Clardy J. Natural products and synthetic biology. Acs Synthetic Biology. 3: 745-7. PMID 24742095 DOI: 10.1021/Sb400025P  0.567
2014 Gavrish E, Sit CS, Cao S, Kandror O, Spoering A, Peoples A, Ling L, Fetterman A, Hughes D, Bissell A, Torrey H, Akopian T, Mueller A, Epstein S, Goldberg A, ... Clardy J, et al. Lassomycin, a ribosomally synthesized cyclic peptide, kills mycobacterium tuberculosis by targeting the ATP-dependent protease ClpC1P1P2. Chemistry & Biology. 21: 509-18. PMID 24684906 DOI: 10.1016/J.Chembiol.2014.01.014  0.709
2014 Böttcher T, Clardy J. A chimeric siderophore halts swarming Vibrio. Angewandte Chemie (International Ed. in English). 53: 3510-3. PMID 24615751 DOI: 10.1002/Anie.201310729  0.592
2014 Stallforth P, Clardy J. Atlas for drug discovery. Proceedings of the National Academy of Sciences of the United States of America. 111: 3655-6. PMID 24554079 DOI: 10.1073/Pnas.1400516111  0.665
2014 Derbyshire ER, Min J, Guiguemde WA, Clark JA, Connelly MC, Magalhães AD, Guy RK, Clardy J. Dihydroquinazolinone inhibitors of proliferation of blood and liver stage malaria parasites. Antimicrobial Agents and Chemotherapy. 58: 1516-22. PMID 24366746 DOI: 10.1128/Aac.02148-13  0.62
2014 Ramadhar TR, Beemelmanns C, Currie CR, Clardy J. Bacterial symbionts in agricultural systems provide a strategic source for antibiotic discovery. The Journal of Antibiotics. 67: 53-8. PMID 23921819 DOI: 10.1038/Ja.2013.77  0.784
2014 Ramadhar T, Zheng S, Chen Y, Clardy J. The Crystalline Sponge Method: Synthetic and Crystallographic Guidelines Acta Crystallographica Section a Foundations and Advances. 70: C1784-C1784. DOI: 10.1107/S2053273314082163  0.729
2014 Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J. Cover Picture: Chemical Interrogation of the Malaria Kinome (ChemBioChem 13/2014) Chembiochem. 15: 1841-1841. DOI: 10.1002/Cbic.201490045  0.596
2013 Stallforth P, Brock DA, Cantley AM, Tian X, Queller DC, Strassmann JE, Clardy J. A bacterial symbiont is converted from an inedible producer of beneficial molecules into food by a single mutation in the gacA gene. Proceedings of the National Academy of Sciences of the United States of America. 110: 14528-33. PMID 23898207 DOI: 10.1073/Pnas.1308199110  0.65
2013 Wieland Brown LC, Penaranda C, Kashyap PC, Williams BB, Clardy J, Kronenberg M, Sonnenburg JL, Comstock LE, Bluestone JA, Fischbach MA. Production of α-galactosylceramide by a prominent member of the human gut microbiota. Plos Biology. 11: e1001610. PMID 23874157 DOI: 10.1371/Journal.Pbio.1001610  0.342
2013 Derbyshire ER, Clardy J. Closing in on a new treatment for sleeping sickness. Elife. 2: e01042. PMID 23853715 DOI: 10.7554/Elife.01042  0.592
2013 Cheng B, Cao S, Vasquez V, Annamalai T, Tamayo-Castillo G, Clardy J, Tse-Dinh YC. Identification of anziaic acid, a lichen depside from Hypotrachyna sp., as a new topoisomerase poison inhibitor. Plos One. 8: e60770. PMID 23593306 DOI: 10.1371/Journal.Pone.0060770  0.338
2013 Stallforth P, Clardy J. X-ray crystallography: One size fits most. Nature. 495: 456-7. PMID 23538827 DOI: 10.1038/495456A  0.677
2013 Böttcher T, Kolodkin-Gal I, Kolter R, Losick R, Clardy J. Synthesis and activity of biomimetic biofilm disruptors. Journal of the American Chemical Society. 135: 2927-30. PMID 23406351 DOI: 10.1021/Ja3120955  0.583
2013 Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F  0.483
2013 Derbyshire ER, Clardy J. Correction: Closing in on a new treatment for sleeping sickness Elife. 2. DOI: 10.7554/Elife.01221  0.584
2013 Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, et al. Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) Natural Product Reports. 30: 1568-1568. DOI: 10.1039/C3Np90040A  0.474
2012 Chandler JR, Truong TT, Silva PM, Seyedsayamdost MR, Carr G, Radey M, Jacobs MA, Sims EH, Clardy J, Greenberg EP. Bactobolin resistance is conferred by mutations in the L2 ribosomal protein. Mbio. 3. PMID 23249812 DOI: 10.1128/Mbio.00499-12  0.586
2012 Findeis MA, Schroeder F, McKee TD, Yager D, Fraering PC, Creaser SP, Austin WF, Clardy J, Wang R, Selkoe D, Eckman CB. Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa. Acs Chemical Neuroscience. 3: 941-51. PMID 23205187 DOI: 10.1021/Cn3000857  0.305
2012 Seyedsayamdost MR, Traxler MF, Clardy J, Kolter R. Old meets new: using interspecies interactions to detect secondary metabolite production in actinomycetes. Methods in Enzymology. 517: 89-109. PMID 23084935 DOI: 10.1016/B978-0-12-404634-4.00005-X  0.6
2012 Adler C, Corbalán NS, Seyedsayamdost MR, Pomares MF, de Cristóbal RE, Clardy J, Kolter R, Vincent PA. Catecholate siderophores protect bacteria from pyochelin toxicity. Plos One. 7: e46754. PMID 23071628 DOI: 10.1371/Journal.Pone.0046754  0.58
2012 Alegado RA, Brown LW, Cao S, Dermenjian RK, Zuzow R, Fairclough SR, Clardy J, King N. A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals. Elife. 1: e00013. PMID 23066504 DOI: 10.7554/Elife.00013  0.498
2012 Carr G, Derbyshire ER, Caldera E, Currie CR, Clardy J. Antibiotic and antimalarial quinones from fungus-growing ant-associated Pseudonocardia sp. Journal of Natural Products. 75: 1806-9. PMID 23025282 DOI: 10.1021/Np300380T  0.662
2012 Stallforth P, Clardy J. Protein evolution: when two become three. Current Biology : Cb. 22: R685-7. PMID 22974996 DOI: 10.1016/J.Cub.2012.07.055  0.635
2012 Traxler MF, Seyedsayamdost MR, Clardy J, Kolter R. Interspecies modulation of bacterial development through iron competition and siderophore piracy. Molecular Microbiology. 86: 628-44. PMID 22931126 DOI: 10.1111/Mmi.12008  0.578
2012 Cao S, Cryan L, Habeshian KA, Murillo C, Tamayo-Castillo G, Rogers MS, Clardy J. Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi. Bioorganic & Medicinal Chemistry Letters. 22: 5885-8. PMID 22910038 DOI: 10.1016/J.Bmcl.2012.07.075  0.331
2012 Seyedsayamdost MR, Cleto S, Carr G, Vlamakis H, João Vieira M, Kolter R, Clardy J. Mixing and matching siderophore clusters: structure and biosynthesis of serratiochelins from Serratia sp. V4. Journal of the American Chemical Society. 134: 13550-3. PMID 22830960 DOI: 10.1021/Ja304941D  0.597
2012 Somvanshi VS, Sloup RE, Crawford JM, Martin AR, Heidt AJ, Kim KS, Clardy J, Ciche TA. A single promoter inversion switches Photorhabdus between pathogenic and mutualistic states. Science (New York, N.Y.). 337: 88-93. PMID 22767929 DOI: 10.1126/Science.1216641  0.523
2012 Crawford JM, Portmann C, Zhang X, Roeffaers MB, Clardy J. Small molecule perimeter defense in entomopathogenic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 10821-6. PMID 22711807 DOI: 10.1073/Pnas.1201160109  0.549
2012 Carr G, Poulsen M, Klassen JL, Hou Y, Wyche TP, Bugni TS, Currie CR, Clardy J. Microtermolides A and B from termite-associated Streptomyces sp. and structural revision of vinylamycin. Organic Letters. 14: 2822-5. PMID 22591554 DOI: 10.1021/Ol301043P  0.336
2012 Derbyshire ER, Prudêncio M, Mota MM, Clardy J. Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proceedings of the National Academy of Sciences of the United States of America. 109: 8511-6. PMID 22586124 DOI: 10.1073/Pnas.1118370109  0.619
2012 Crawford JM, Clardy J. Microbial genome mining answers longstanding biosynthetic questions. Proceedings of the National Academy of Sciences of the United States of America. 109: 7589-90. PMID 22550177 DOI: 10.1073/Pnas.1205361109  0.553
2012 Kolodkin-Gal I, Cao S, Chai L, Böttcher T, Kolter R, Clardy J, Losick R. A self-produced trigger for biofilm disassembly that targets exopolysaccharide. Cell. 149: 684-92. PMID 22541437 DOI: 10.1016/J.Cell.2012.02.055  0.561
2012 Derbyshire ER, Mazitschek R, Clardy J. Characterization of Plasmodium liver stage inhibition by halofuginone. Chemmedchem. 7: 844-9. PMID 22438279 DOI: 10.1002/Cmdc.201200045  0.615
2012 Ymele-Leki P, Cao S, Sharp J, Lambert KG, McAdam AJ, Husson RN, Tamayo G, Clardy J, Watnick PI. A high-throughput screen identifies a new natural product with broad-spectrum antibacterial activity. Plos One. 7: e31307. PMID 22359585 DOI: 10.1371/Journal.Pone.0031307  0.311
2012 Santagata S, Xu YM, Wijeratne EM, Kontnik R, Rooney C, Perley CC, Kwon H, Clardy J, Kesari S, Whitesell L, Lindquist S, Gunatilaka AA. Using the heat-shock response to discover anticancer compounds that target protein homeostasis. Acs Chemical Biology. 7: 340-9. PMID 22050377 DOI: 10.1021/Cb200353M  0.789
2012 Alegado RA, Brown LW, Cao S, Dermenjian RK, Zuzow R, Fairclough SR, Clardy J, King N. Author response: A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals Elife. DOI: 10.7554/Elife.00013.030  0.463
2012 Derbyshire ER, Mazitschek R, Clardy J. Cover Picture: Characterization of Plasmodium Liver Stage Inhibition by Halofuginone (ChemMedChem 5/2012) Chemmedchem. 7: 745-745. DOI: 10.1002/Cmdc.201290018  0.589
2011 Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, ... ... Clardy J, et al. Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors. Chemistry & Biology. 18: 1602-10. PMID 22195562 DOI: 10.1016/J.Chembiol.2011.09.016  0.639
2011 Derbyshire ER, Mota MM, Clardy J. The next opportunity in anti-malaria drug discovery: the liver stage. Plos Pathogens. 7: e1002178. PMID 21966266 DOI: 10.1371/Journal.Ppat.1002178  0.601
2011 Crawford JM, Mahlstedt SA, Malcolmson SJ, Clardy J, Walsh CT. Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis. Chemistry & Biology. 18: 1102-12. PMID 21944749 DOI: 10.1016/J.Chembiol.2011.07.009  0.541
2011 Seyedsayamdost MR, Carr G, Kolter R, Clardy J. Roseobacticides: small molecule modulators of an algal-bacterial symbiosis. Journal of the American Chemical Society. 133: 18343-9. PMID 21928816 DOI: 10.1021/Ja207172S  0.616
2011 Crawford JM, Portmann C, Kontnik R, Walsh CT, Clardy J. NRPS substrate promiscuity diversifies the xenematides. Organic Letters. 13: 5144-7. PMID 21888371 DOI: 10.1021/Ol2020237  0.785
2011 Seyedsayamdost MR, Traxler MF, Zheng SL, Kolter R, Clardy J. Structure and biosynthesis of amychelin, an unusual mixed-ligand siderophore from Amycolatopsis sp. AA4. Journal of the American Chemical Society. 133: 11434-7. PMID 21699219 DOI: 10.1021/Ja203577E  0.627
2011 Carr G, Seyedsayamdost MR, Chandler JR, Greenberg EP, Clardy J. Sources of diversity in bactobolin biosynthesis by Burkholderia thailandensis E264. Organic Letters. 13: 3048-51. PMID 21615115 DOI: 10.1021/Ol200922S  0.6
2011 Crawford JM, Clardy J. Bacterial symbionts and natural products. Chemical Communications (Cambridge, England). 47: 7559-66. PMID 21594283 DOI: 10.1039/C1Cc11574J  0.564
2011 Seyedsayamdost MR, Case RJ, Kolter R, Clardy J. The Jekyll-and-Hyde chemistry of Phaeobacter gallaeciensis. Nature Chemistry. 3: 331-5. PMID 21430694 DOI: 10.1038/Nchem.1002  0.58
2011 Poulsen M, Oh DC, Clardy J, Currie CR. Chemical analyses of wasp-associated streptomyces bacteria reveal a prolific potential for natural products discovery. Plos One. 6: e16763. PMID 21364940 DOI: 10.1371/Journal.Pone.0016763  0.359
2011 Oh DC, Poulsen M, Currie CR, Clardy J. Sceliphrolactam, a polyene macrocyclic lactam from a wasp-associated Streptomyces sp. Organic Letters. 13: 752-5. PMID 21247188 DOI: 10.1021/Ol102991D  0.32
2010 Mao Y, Xu X, Xu W, Ishida Y, Leal WS, Ames JB, Clardy J. Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone. Proceedings of the National Academy of Sciences of the United States of America. 107: 19102-7. PMID 20956299 DOI: 10.1073/Pnas.1012274107  0.513
2010 Crawford JM, Clardy J. Biosynthesis: not just passing through. Nature Chemistry. 2: 805-7. PMID 20861892 DOI: 10.1038/Nchem.848  0.55
2010 Cao S, Blodgett JA, Clardy J. Targeted discovery of polycyclic tetramate macrolactams from an environmental Streptomyces strain. Organic Letters. 12: 4652-4. PMID 20843016 DOI: 10.1021/Ol1020064  0.787
2010 Cao S, Ross L, Tamayo G, Clardy J. Asterogynins: secondary metabolites from a Costa Rican endophytic fungus. Organic Letters. 12: 4661-3. PMID 20839869 DOI: 10.1021/Ol101972G  0.317
2010 Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R. A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity. Organic Letters. 12: 3998-4001. PMID 20718474 DOI: 10.1021/Ol101566H  0.306
2010 Blodgett JA, Oh DC, Cao S, Currie CR, Kolter R, Clardy J. Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria. Proceedings of the National Academy of Sciences of the United States of America. 107: 11692-7. PMID 20547882 DOI: 10.1073/Pnas.1001513107  0.797
2010 Kontnik R, Crawford JM, Clardy J. Exploiting a global regulator for small molecule discovery in Photorhabdus luminescens. Acs Chemical Biology. 5: 659-65. PMID 20524642 DOI: 10.1021/Cb100117K  0.784
2010 D'Onofrio A, Crawford JM, Stewart EJ, Witt K, Gavrish E, Epstein S, Clardy J, Lewis K. Siderophores from neighboring organisms promote the growth of uncultured bacteria. Chemistry & Biology. 17: 254-64. PMID 20338517 DOI: 10.1016/J.Chembiol.2010.02.010  0.544
2010 Seyedsayamdost MR, Chandler JR, Blodgett JA, Lima PS, Duerkop BA, Oinuma K, Greenberg EP, Clardy J. Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Organic Letters. 12: 716-9. PMID 20095633 DOI: 10.1021/Ol902751X  0.776
2010 Dawlaty J, Zhang X, Fischbach MA, Clardy J. Dapdiamides, tripeptide antibiotics formed by unconventional amide ligases. Journal of Natural Products. 73: 441-6. PMID 20041689 DOI: 10.1021/Np900685Z  0.789
2010 Blasiak LC, Clardy J. Discovery of 3-formyl-tyrosine metabolites from Pseudoalteromonas tunicata through heterologous expression. Journal of the American Chemical Society. 132: 926-7. PMID 20041686 DOI: 10.1021/Ja9097862  0.305
2010 Crawford JM, Kontnik R, Clardy J. Regulating alternative lifestyles in entomopathogenic bacteria. Current Biology : Cb. 20: 69-74. PMID 20022247 DOI: 10.1016/J.Cub.2009.10.059  0.783
2010 Cronan JM, Lee A, Liang J, Clardy J, Cardellina JH. Chemical modification of the insecticidal briantheins X and Y. Journal of Natural Products. 73: 346-51. PMID 19810733 DOI: 10.1021/Np800381N  0.327
2010 Barash I, Manulis S, Kashman Y, Springer JP, Chen MH, Clardy J, Strobel GA. Crystallization and X-ray Analysis of Stemphyloxin I, a Phytotoxin from Stemphylium botryosum. Science (New York, N.Y.). 220: 1065-6. PMID 17754554 DOI: 10.1126/Science.220.4601.1065  0.311
2010 GUSTAFSON KR, MUNRO MHG, BLUNT JW, CARDELLINA JHI, MCMAHON JB, GULAKOWSKI RJ, CRAGG GM, COX PA, BRINEN LS, CLARDY J, BOYD MR. ChemInform Abstract: HIV Inhibitory Natural Products. Part 3. Diterpenes from Homalanthus acuminatus and Chrysobalanus icaco. Cheminform. 22: no-no. DOI: 10.1002/chin.199136246  0.655
2009 Miller SJ, Clardy J. Natural products: Beyond grind and find. Nature Chemistry. 1: 261-3. PMID 21378864 DOI: 10.1038/Nchem.269  0.313
2009 Freinkman E, Oh DC, Scott JJ, Currie CR, Clardy J. Bionectriol A, a polyketide glycoside from the fungus Bionectria sp. associated with the fungus-growing ant, Apterostigma dentigerum. Tetrahedron Letters. 50: 6834-6837. PMID 20160864 DOI: 10.1016/J.Tetlet.2009.09.120  0.321
2009 Martyn DC, Beletsky G, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Liang B, Clardy J. Synthesis and in vitro DMPK profiling of a 1,2-dioxolane-based library with activity against Plasmodium falciparum. Bioorganic & Medicinal Chemistry Letters. 19: 5657-60. PMID 19699641 DOI: 10.1016/J.Bmcl.2009.08.024  0.313
2009 Mojsilovic-Petrovic J, Nedelsky N, Boccitto M, Mano I, Georgiades SN, Zhou W, Liu Y, Neve RL, Taylor JP, Driscoll M, Clardy J, Merry D, Kalb RG. FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8236-47. PMID 19553463 DOI: 10.1523/Jneurosci.1805-09.2009  0.72
2009 Butcher RA, Ragains JR, Clardy J. An indole-containing dauer pheromone component with unusual dauer inhibitory activity at higher concentrations. Organic Letters. 11: 3100-3. PMID 19545143 DOI: 10.1021/Ol901011C  0.305
2009 Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF. Colorimetric high-throughput screen for detection of heme crystallization inhibitors. Antimicrobial Agents and Chemotherapy. 53: 2564-8. PMID 19307367 DOI: 10.1128/Aac.01466-08  0.683
2009 Oh DC, Scott JJ, Currie CR, Clardy J. Mycangimycin, a polyene peroxide from a mutualist Streptomyces sp. Organic Letters. 11: 633-6. PMID 19125624 DOI: 10.1021/Ol802709X  0.328
2008 Martyn DC, Ramirez AP, Beattie MJ, Cortese JF, Patel V, Rush MA, Woerpel KA, Clardy J. Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum. Bioorganic & Medicinal Chemistry Letters. 18: 6521-4. PMID 18993067 DOI: 10.1016/J.Bmcl.2008.10.083  0.688
2008 Maloney KN, Fujita M, Eggert US, Schroeder FC, Field CM, Mitchison TJ, Clardy J. Actin-aggregating cucurbitacins from Physocarpus capitatus. Journal of Natural Products. 71: 1927-9. PMID 18959442 DOI: 10.1021/Np8005259  0.711
2008 Patel V, Booker M, Kramer M, Ross L, Celatka CA, Kennedy LM, Dvorin JD, Duraisingh MT, Sliz P, Wirth DF, Clardy J. Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. The Journal of Biological Chemistry. 283: 35078-85. PMID 18842591 DOI: 10.1074/Jbc.M804990200  0.314
2008 Scott JJ, Oh DC, Yuceer MC, Klepzig KD, Clardy J, Currie CR. Bacterial protection of beetle-fungus mutualism. Science (New York, N.Y.). 322: 63. PMID 18832638 DOI: 10.1126/Science.1160423  0.325
2008 Kontnik R, Clardy J. Codinaeopsin, an antimalarial fungal polyketide. Organic Letters. 10: 4149-51. PMID 18698786 DOI: 10.1021/Ol801726K  0.793
2008 Kontnik R, Bosak T, Butcher RA, Brocks JJ, Losick R, Clardy J, Pearson A. Sporulenes, heptaprenyl metabolites from Bacillus subtilis spores. Organic Letters. 10: 3551-4. PMID 18630919 DOI: 10.1021/Ol801314K  0.791
2008 Georgiades SN, Clardy J. Synthetic libraries of tyrosine-derived bacterial metabolites. Bioorganic & Medicinal Chemistry Letters. 18: 3117-21. PMID 17983747 DOI: 10.1016/J.Bmcl.2007.10.058  0.742
2008 Kontnik R, Bosak T, Butcher R, Brocks J, Losick R, Pearson A, Clardy J. Sporulenes, three new polycyclic terpenoids from Bacillus subtilis spores Planta Medica. 74. DOI: 10.1055/S-0028-1084443  0.78
2008 Oh D, Scott J, Poulsen M, Currie C, Clardy J. Discovery of new secondary metabolites mediating insect-microorganism symbioses Planta Medica. 74. DOI: 10.1055/S-0028-1083882  0.312
2007 Lautenschlager C, Leal WS, Clardy J. Bombyx mori Pheromone-Binding Protein Binding Nonpheromone Ligands: Implications for Pheromone Recognition Structure. 15: 1148-1154. PMID 17850754 DOI: 10.1016/J.Str.2007.07.013  0.771
2007 Schmitz K, Haggarty SJ, McPherson OM, Clardy J, Koehler AN. Detecting binding interactions using microarrays of natural product extracts. Journal of the American Chemical Society. 129: 11346-7. PMID 17718493 DOI: 10.1021/Ja073965S  0.546
2007 Clardy J, Brady SF. Cyclic AMP directly activates NasP, an N-acyl amino acid antibiotic biosynthetic enzyme cloned from an uncultured beta-proteobacterium. Journal of Bacteriology. 189: 6487-9. PMID 17586635 DOI: 10.1128/Jb.00457-07  0.543
2007 Butcher RA, Schroeder FC, Fischbach MA, Straight PD, Kolter R, Walsh CT, Clardy J. The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 104: 1506-9. PMID 17234808 DOI: 10.1073/Pnas.0610503104  0.331
2006 Clardy J, Fischbach MA, Walsh CT. New antibiotics from bacterial natural products. Nature Biotechnology. 24: 1541-50. PMID 17160060 DOI: 10.1038/Nbt1266  0.318
2006 Amagata T, Morinaka BI, Amagata A, Tenney K, Valeriote FA, Lobkovsky E, Clardy J, Crews P. A chemical study of cyclic depsipeptides produced by a sponge-derived fungus Journal of Natural Products. 69: 1560-1565. PMID 17125221 DOI: 10.1021/Np060178K  0.349
2006 Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, Rodina A, Nieto M, Du J, Stegmaier K, Raj SM, Maloney KN, Clardy J, Hahn WC, Chiosis G, Golub TR. Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell. 10: 321-30. PMID 17010675 DOI: 10.1016/J.Ccr.2006.09.005  0.731
2006 Van Wagoner RM, Clardy J. FeeM, an N-acyl amino acid synthase from an uncultured soil microbe: structure, mechanism, and acyl carrier protein binding. Structure (London, England : 1993). 14: 1425-35. PMID 16962973 DOI: 10.1016/J.Str.2006.07.005  0.33
2006 Georgiades SN, Clardy J. Preparation of a psammaplysene-based library. Organic Letters. 8: 4251-4. PMID 16956199 DOI: 10.1021/Ol061599W  0.733
2006 Maloney KN, Hao W, Xu J, Gibbons J, Hucul J, Roll D, Brady SF, Schroeder FC, Clardy J. Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus. Organic Letters. 8: 4067-70. PMID 16928075 DOI: 10.1021/Ol061556F  0.78
2006 Jin M, Fischbach MA, Clardy J. A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid. Journal of the American Chemical Society. 128: 10660-1. PMID 16910643 DOI: 10.1021/Ja063194C  0.53
2006 Smith PL, Maloney KN, Pothen RG, Clardy J, Clapham DE. Bisandrographolide from Andrographis paniculata activates TRPV4 channels. The Journal of Biological Chemistry. 281: 29897-904. PMID 16899456 DOI: 10.1074/Jbc.M605394200  0.721
2006 Thammana S, Suzuki H, Lobkovsky E, Clardy J, Shimizu Y. Isolation and structure assignment of an iminotetrasaccharide from a cultured filamentous cyanobacterium Anabaena sp. Journal of Natural Products. 69: 365-8. PMID 16562836 DOI: 10.1021/Np050401Y  0.357
2006 Hurt DE, Widom J, Clardy J. Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor. Acta Crystallographica. Section D, Biological Crystallography. 62: 312-23. PMID 16510978 DOI: 10.1107/S0907444905042642  0.675
2006 Hurt DE, Sutton AE, Clardy J. Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase. Bioorganic & Medicinal Chemistry Letters. 16: 1610-5. PMID 16406782 DOI: 10.1016/J.Bmcl.2005.12.029  0.68
2005 Brady SF, Clardy J. Systematic investigation of the Escherichia coli metabolome for the biosynthetic origin of an isocyanide carbon atom. Angewandte Chemie (International Ed. in English). 44: 7045-8. PMID 16217820 DOI: 10.1002/Anie.200501942  0.527
2005 Brady SF, Clardy J. Cloning and heterologous expression of isocyanide biosynthetic genes from environmental DNA. Angewandte Chemie (International Ed. in English). 44: 7063-5. PMID 16206308 DOI: 10.1002/Anie.200501941  0.515
2005 Clardy J. Using genomics to deliver natural products from symbiotic bacteria. Genome Biology. 6: 232. PMID 16168093 DOI: 10.1186/Gb-2005-6-9-232  0.33
2005 Georgiades SN, Clardy J. Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export. Organic Letters. 7: 4091-4. PMID 16146359 DOI: 10.1021/Ol0513286  0.733
2005 Lautenschlager C, Leal WS, Clardy J. Coil-to-helix transition and ligand release of Bombyx mori pheromone-binding protein Biochemical and Biophysical Research Communications. 335: 1044-1050. PMID 16111659 DOI: 10.1016/J.Bbrc.2005.07.176  0.765
2005 Brady SF, Clardy J. N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli. Organic Letters. 7: 3613-6. PMID 16092832 DOI: 10.1021/Ol0509585  0.57
2005 Weibel DB, Lee A, Mayer M, Brady SF, Bruzewicz D, Yang J, Diluzio WR, Clardy J, Whitesides GM. Bacterial printing press that regenerates its ink: contact-printing bacteria using hydrogel stamps. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 6436-42. PMID 15982051 DOI: 10.1021/La047173C  0.536
2005 Clardy J, Walsh C. Lessons from natural molecules. Nature. 432: 829-37. PMID 15602548 DOI: 10.1038/Nature03194  0.301
2004 Brady SF, Chao CJ, Clardy J. Long-chain N-acyltyrosine synthases from environmental DNA. Applied and Environmental Microbiology. 70: 6865-70. PMID 15528554 DOI: 10.1128/Aem.70.11.6865-6870.2004  0.568
2004 Brady SF, Clardy J. Palmitoylputrescine, an antibiotic isolated from the heterologous expression of DNA extracted from bromeliad tank water. Journal of Natural Products. 67: 1283-6. PMID 15332842 DOI: 10.1021/Np0499766  0.558
2004 Stierle DB, Stierle AA, Hobbs JD, Stokken J, Clardy J. Berkeleydione and berkeleytrione, new bioactive metabolites from an acid mine organism. Organic Letters. 6: 1049-52. PMID 15012097 DOI: 10.1021/Ol049852K  0.354
2004 Sonnenschein RN, Farias JJ, Tenney K, Mooberry SL, Lobkovsky E, Clardy J, Crews P. A further study of the cytotoxic constituents of a milnamide-producing sponge Organic Letters. 6: 779-782. PMID 14986973 DOI: 10.1021/Ol036446C  0.366
2003 Amagata T, Amagata A, Tenney K, Valeriote FA, Lobkovsky E, Clardy J, Crews P. Unusual C25 Steroids Produced by a Sponge-Derived Penicillium citrinum Organic Letters. 5: 4393-4396. PMID 14602008 DOI: 10.1021/Ol0356800  0.372
2003 Calero G, Gupta P, Nonato MC, Tandel S, Biehl ER, Hofmann SL, Clardy J. The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2 Journal of Biological Chemistry. 278: 37957-37964. PMID 12855696 DOI: 10.1074/Jbc.M301225200  0.678
2003 Jin M, Wright SA, Beer SV, Clardy J. The biosynthetic gene cluster of Pantocin a provides insights into biosynthesis and a tool for screening. Angewandte Chemie (International Ed. in English). 42: 2902-5. PMID 12833354 DOI: 10.1002/Anie.200351054  0.491
2003 Jin M, Liu L, Wright SA, Beer SV, Clardy J. Structural and functional analysis of pantocin A: an antibiotic from Pantoea agglomerans discovered by heterologous expression of cloned genes. Angewandte Chemie (International Ed. in English). 42: 2898-901. PMID 12833353 DOI: 10.1002/Anie.200351053  0.521
2003 Garo E, Starks CM, Jensen PR, Fenical W, Lobkovsky E, Clardy J. Trichodermamides A and B, cytotoxic modified dipeptides from the marine-derived fungus Trichoderma virens. Journal of Natural Products. 66: 423-6. PMID 12662106 DOI: 10.1021/Np0204390  0.332
2003 Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR. Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases Journal of Natural Products. 66: 230-235. PMID 12608855 DOI: 10.1021/Np020462L  0.308
2003 Sinars CR, Cheung-Flynn J, Rimerman RA, Scammell JG, Smith DF, Clardy J. Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes. Proceedings of the National Academy of Sciences of the United States of America. 100: 868-73. PMID 12538866 DOI: 10.1073/Pnas.0231020100  0.766
2003 Brady SF, Clardy J. Synthesis of long-chain fatty acid enol esters isolated from an environmental DNA clone. Organic Letters. 5: 121-4. PMID 12529120 DOI: 10.1021/Ol0267681  0.581
2003 Ireland CM, Aalbersberg W, Andersen RJ, Ayral-Kaloustian S, Berlinck RGS, Bernan V, Carter G, Churchill ACL, Clardy J, Concepcion GP, De Silva ED, Discafani C, Fojo T, Frost P, Gibson D, et al. Anticancer agents from unique natural products sources Pharmaceutical Biology. 41: 15-38. DOI: 10.1080/1388020039051742  0.544
2002 Thale Z, Johnson T, Tenney K, Wenzel PJ, Lobkovsky E, Clardy J, Media J, Pietraszkiewicz H, Valeriote FA, Crews P. Structures and cytotoxic properties of sponge-derived bisannulated acridines. The Journal of Organic Chemistry. 67: 9384-91. PMID 12492342 DOI: 10.1021/Jo026459O  0.335
2002 Calero G, Wilson KF, Ly T, Rios-Steiner JL, Clardy JC, Cerione RA. Structural basis of m7GpppG binding to the nuclear cap-binding protein complex. Nature Structural Biology. 9: 912-7. PMID 12434151 DOI: 10.1038/Nsb874  0.675
2002 Gillespie DE, Brady SF, Bettermann AD, Cianciotto NP, Liles MR, Rondon MR, Clardy J, Goodman RM, Handelsman J. Isolation of antibiotics turbomycin a and B from a metagenomic library of soil microbial DNA. Applied and Environmental Microbiology. 68: 4301-6. PMID 12200279 DOI: 10.1128/Aem.68.9.4301-4306.2002  0.584
2002 Brady SF, Chao CJ, Clardy J. New natural product families from an environmental DNA (eDNA) gene cluster. Journal of the American Chemical Society. 124: 9968-9. PMID 12188643 DOI: 10.1021/Ja0268985  0.574
2002 Salomon CE, Williams DH, Lobkovsky E, Clardy JC, Faulkner DJ. Relative and absolute stereochemistry of the didemnaketals, metabolites of a Palauan ascidian, Didemnum sp. Organic Letters. 4: 1699-702. PMID 12000277 DOI: 10.1021/Ol025904Z  0.35
2002 Anjaneyulu AS, Rao VL, Lobkovsky E, Clardy J. Ceriopsin E, a new epoxy ent-kaurene diterpenoid from Ceriops decandra. Journal of Natural Products. 65: 592-4. PMID 11975510 DOI: 10.1021/Np010540P  0.319
2002 Wagenaar MM, Gibson DM, Clardy J. Akanthomycin, a new antibiotic pyridone from the entomopathogenic fungus Akanthomyces gracilis. Organic Letters. 4: 671-3. PMID 11869098 DOI: 10.1021/Ol016737Q  0.71
2002 Cueto M, Jensen PR, Kauffman C, Fenical W, Lobkovsky E, Clardy J. Pestalone, a new antibiotic produced by a marine fungus in response to bacterial challenge. Journal of Natural Products. 64: 1444-6. PMID 11720529 DOI: 10.1021/Np0102713  0.37
2001 Sutton AE, Clardy J. Synthesis and biological evaluation of analogues of the antibiotic pantocin B. Journal of the American Chemical Society. 123: 9935-46. PMID 11592872 DOI: 10.1021/Ja003770J  0.336
2001 Brady SF, Bondi SM, Clardy J. The guanacastepenes: a highly diverse family of secondary metabolites produced by an endophytic fungus. Journal of the American Chemical Society. 123: 9900-1. PMID 11583556 DOI: 10.1021/Ja016176Y  0.545
2001 Wagenaar MM, Clardy J. Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint. Journal of Natural Products. 64: 1006-9. PMID 11520215 DOI: 10.1021/Np010020U  0.711
2001 Wagenaar MM, Clardy J. Two new roridins isolated from Myrothecium sp. The Journal of Antibiotics. 54: 517-20. PMID 11513043 DOI: 10.7164/Antibiotics.54.517  0.682
2001 Brady SF, Chao CJ, Handelsman J, Clardy J. Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA. Organic Letters. 3: 1981-4. PMID 11418029 DOI: 10.1021/Ol015949K  0.56
2001 Qiu SX, Nguyen VH, Le TX, Gu JQ, Lobkovsky E, Tran CK, Soejarto DD, Clardy J, Pezzuto JM, Dong Y, Mai VT, Le MH, Fong HH. A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography. Phytochemistry. 56: 775-80. PMID 11314967 DOI: 10.1016/S0031-9422(00)00463-5  0.335
2000 Wagenaar MM, Corwin J, Strobel G, Clardy J. Three new cytochalasins produced by an endophytic fungus in the genus Rhinocladiella. Journal of Natural Products. 63: 1692-5. PMID 11141120 DOI: 10.1021/Np0002942  0.704
2000 Brady SF, Singh MP, Janso JE, Clardy J. Cytoskyrins A and B, new BIA active bisanthraquinones isolated from an endophytic fungus. Organic Letters. 2: 4047-9. PMID 11112640 DOI: 10.1021/Ol006681K  0.606
2000 Brady SF, Wagenaar MM, Singh MP, Janso JE, Clardy J. The cytosporones, new octaketide antibiotics isolated from an endophytic fungus. Organic Letters. 2: 4043-6. PMID 11112639 DOI: 10.1021/Ol006680S  0.774
2000 Brady SF, Clardy J. CR377, a new pentaketide antifungal agent isolated from an endophytic fungus. Journal of Natural Products. 63: 1447-8. PMID 11076576 DOI: 10.1021/Np990568P  0.57
2000 Jimenez JI, Yoshida WY, Scheuer PJ, Lobkovsky E, Clardy J, Kelly M. Honulactones: New bishomoscalarane sesterterpenes from the Indonesian sponge Strepsichordaia aliena Journal of Organic Chemistry. 65: 6837-6840. PMID 11030999 DOI: 10.1021/Jo991924B  0.306
2000 Rondon MR, August PR, Bettermann AD, Brady SF, Grossman TH, Liles MR, Loiacono KA, Lynch BA, MacNeil IA, Minor C, Tiong CL, Gilman M, Osburne MS, Clardy J, Handelsman J, et al. Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms. Applied and Environmental Microbiology. 66: 2541-7. PMID 10831436 DOI: 10.1128/Aem.66.6.2541-2547.2000  0.558
2000 Singh MP, Janso JE, Luckman SW, Brady SF, Clardy J, Greenstein M, Maiese WM. Biological activity of guanacastepene, a novel diterpenoid antibiotic produced by an unidentified fungus CR115. The Journal of Antibiotics. 53: 256-61. PMID 10819296 DOI: 10.7164/Antibiotics.53.256  0.578
2000 Das AK, Bellizzi JJ, Tandel S, Biehl E, Clardy J, Hofmann SL. Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride. The Journal of Biological Chemistry. 275: 23847-51. PMID 10801859 DOI: 10.1074/Jbc.M002758200  0.744
2000 Bellizzi JJ, Widom J, Kemp C, Lu JY, Das AK, Hofmann SL, Clardy J. The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 4573-8. PMID 10781062 DOI: 10.1073/Pnas.080508097  0.737
2000 Li JY, Strobel G, Harper J, Lobkovsky E, Clardy J. Cryptocin, a potent tetramic acid antimycotic from the endophytic fungus Cryptosporiopsis cf. quercina. Organic Letters. 2: 767-70. PMID 10754679 DOI: 10.1021/Ol000008D  0.328
2000 Sandler BH, Nikonova L, Leal WS, Clardy J. Sexual attraction in the silkworm moth: structure of the pheromone-binding-protein-bombykol complex. Chemistry & Biology. 7: 143-51. PMID 10662696 DOI: 10.1016/S1074-5521(00)00078-8  0.668
2000 Brady SF, Singh MP, Janso JE, Clardy J. Guanacastepene, a fungal-derived diterpene antibiotic with a new carbon skeleton Journal of the American Chemical Society. 122: 2116-2117. DOI: 10.1021/Ja993835M  0.552
2000 Brady SF, Clardy J. Long-chain N-acyl amino acid antibiotics isolated from heterologously expressed environmental DNA [20] Journal of the American Chemical Society. 122: 12903-12904. DOI: 10.1021/Ja002990U  0.538
1999 Bellizzi JJ, Widom J, Kemp CW, Clardy J. Producing selenomethionine-labeled proteins with a baculovirus expression vector system. Structure (London, England : 1993). 7: R263-7. PMID 10574801 DOI: 10.1016/S0969-2126(00)80020-9  0.726
1999 Stohl EA, Brady SF, Clardy J, Handelsman J. ZmaR, a novel and widespread antibiotic resistance determinant that acetylates zwittermicin A. Journal of Bacteriology. 181: 5455-60. PMID 10464220 DOI: 10.1128/Jb.181.17.5455-5460.1999  0.57
1999 Wang Y, Mueller UG, Clardy J. Journal of Chemical Ecology. 25: 935-941. DOI: 10.1023/A:1020861221126  0.332
1999 Ahmad VU, Zahid M, Ali MS, Ali Z, Jassbi AR, Abbas M, Clardy J, Lobkovsky E, Tareen RB, Iqbal MZ. Salvadiones-A and -B: Two Terpenoids Having Novel Carbon Skeleta from Salvia bucharica Journal of Organic Chemistry. 64: 8465-8467. DOI: 10.1021/Jo990024S  0.309
1999 Renner MK, Shen Y, Cheng X, Jensen PR, Frankmoelle W, Kauffman CA, Fenical W, Lobkovsky E, Clardy J. Cyclomarins A−C, New Antiinflammatory Cyclic Peptides Produced by a Marine Bacterium (Streptomycessp.) Journal of the American Chemical Society. 121: 11273-11276. DOI: 10.1021/Ja992482O  0.371
1998 Handelsman J, Rondon MR, Brady SF, Clardy J, Goodman RM. Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products. Chemistry & Biology. 5: R245-9. PMID 9818143 DOI: 10.1016/S1074-5521(98)90108-9  0.521
1998 Liu S, Widom J, Kemp CW, Crews CM, Clardy J. Structure of human methionine aminopeptidase-2 complexed with fumagillin. Science (New York, N.Y.). 282: 1324-7. PMID 9812898 DOI: 10.1126/Science.282.5392.1324  0.331
1998 Sugawara F, Uzawa J, Esumi Y, Suzuki M, Yoshida S, Strobel G, Steiner JLR, Clardy J. Phytotoxins from the Septoria spp. plant pathogenic fungus on leafy spurge. Bioscience, Biotechnology, and Biochemistry. 62: 638-642. PMID 9614694 DOI: 10.1271/Bbb.62.638  0.324
1998 Lee AY, Smitka TA, Bonjouklian R, Clardy J. Atomic structure of the trypsin-A90720A complex: a unified approach to structure and function. Chemistry & Biology. 1: 113-7. PMID 9383379 DOI: 10.1016/1074-5521(94)90049-3  0.33
1998 Sandler B, Murakami M, Clardy J. Atomic Structure of the Trypsin-Aeruginosin 98-B Complex Journal of the American Chemical Society. 120: 595-596. DOI: 10.1021/Ja972991V  0.666
1998 Williams DE, Bombuwala K, Lobkovsky E, de Silva E, Karunatne V, Allen TM, Clardy J, Andersen RJ. Ambewelamides A and B, antineoplastic epidithiapiperazinediones isolated from the lichen Usnea sp. Tetrahedron Letters. 39: 9579-9582. DOI: 10.1016/S0040-4039(98)02277-1  0.332
1998 Anjaneyulu ASR, Venugopal MJRV, Sarada P, Clardy J, Lobkovsky E. Havellockate, A Novel Seco and Spiro Lactone Diterpenoid from the Indian Ocean Soft Coral Sinularia granosa Tetrahedron Letters. 39: 139-142. DOI: 10.1016/S0040-4039(97)10470-1  0.309
1997 Atta-ur-Rahman, Nasreen A, Akhtar F, Shekhani MS, Clardy J, Parvez M, Choudhary MI. Antifungal diterpenoid alkaloids from Delphinium denudatum. Journal of Natural Products. 60: 472-4. PMID 9170290 DOI: 10.1021/Np960663N  0.474
1997 Vervoort HC, Richards-Gross SE, Fenical W, Lee AY, Clardy J. Didemnimides A−D: Novel, Predator-Deterrent Alkaloids from the Caribbean Mangrove Ascidian Didemnum conchyliatum Journal of Organic Chemistry. 62: 1486-1490. DOI: 10.1021/Jo961789S  0.33
1996 Schroeder DR, Colson KL, Klohr SE, Lee MS, Matson JA, Brinen LS, Clardy J. Pyrrolosporin A, a new antitumor antibiotic from Micromonospora sp. C39217-R109-7. II. Isolation, physico-chemical properties, spectroscopic study and X-ray analysis. The Journal of Antibiotics. 49: 865-72. PMID 8931719 DOI: 10.7164/Antibiotics.49.865  0.661
1996 Milner JL, Silo-Suh L, Lee JC, Haiyin HE, Clardy J, Handelsman JO. Production of kanosamine by Bacillus cereus UW85 Applied and Environmental Microbiology. 62: 3061-3065. PMID 8702302 DOI: 10.1128/Aem.62.8.3061-3065.1996  0.313
1996 Liang J, Chen JK, Schreiber ST, Clardy J. Crystal structure of P13K SH3 domain at 20 angstroms resolution. Journal of Molecular Biology. 257: 632-43. PMID 8648629 DOI: 10.1006/Jmbi.1996.0190  0.303
1996 Kirst HA, Mynderse JS, Martin JW, Baker PJ, Paschal JW, Rios Steiner JL, Lobkovsky E, Clardy J. Structure of the spiroketal-macrolide ossamycin. The Journal of Antibiotics. 49: 162-7. PMID 8621357 DOI: 10.7164/Antibiotics.49.162  0.361
1996 Pulici M, Sugawara F, Koshino H, Uzawa J, Yoshida S, Lobkovsky E, Clardy J. A New Isodrimeninol from Pestalotiopsis sp. Journal of Natural Products. 59: 47-48. DOI: 10.1021/Np9600053  0.326
1996 Pulici M, Sugawara F, Koshino H, Uzawa J, Yoshida S, Lobkovsky E, Clardy J. Pestalotiopsins A and B: New Caryophyllenes from an Endophytic Fungus of Taxus brevifolia Journal of Organic Chemistry. 61: 2122-2124. DOI: 10.1021/Jo951736V  0.334
1996 Harrison B, Talapatra S, Lobkovsky E, Clardy J, Crews P. The structure and biogenetic origin of (-) halicyclamine B from a Xestospongia sponge Tetrahedron Letters. 37: 9151-9154. DOI: 10.1016/S0040-4039(96)02165-X  0.35
1996 Lindquist N, Lobkovsky E, Clardy J. Tridentatols A-C, novel natural products of the marine hydroid Tridentata marginata Tetrahedron Letters. 37: 9131-9134. DOI: 10.1016/S0040-4039(96)02157-0  0.319
1996 Montanari AM, Fenical W, Lindquist N, Lee AY, Clardy J. Volutamides A-E, halogenated alkaloids with antifeedant properties from the Atlantic bryozoan Amathia convoluta Tetrahedron. 52: 5371-5380. DOI: 10.1016/0040-4020(96)00188-3  0.325
1995 Kirst HA, Larsen SH, Paschal JW, Occolowitz JL, Creemer LC, Steiner JL, Lobkovsky E, Clardy J. Structure of the new spiroketal-macrolide A82548A. The Journal of Antibiotics. 48: 990-6. PMID 7592067 DOI: 10.7164/Antibiotics.48.990  0.382
1995 Clardy J. The chemistry of signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 92: 56-61. PMID 7529414 DOI: 10.1073/Pnas.92.1.56  0.313
1995 Concepción GP, Foderaro TA, Eldredge GS, Lobkovsky E, Clardy J, Barrows LR, Ireland CM. Topoisomerase II-mediated DNA cleavage by adocia- and xestoquinones from the Philippine sponge Xestospongia sp Journal of Medicinal Chemistry. 38: 4503-4507. PMID 7473578 DOI: 10.1021/Jm00022A016  0.52
1995 Hughes P, Clardy J. Total Synthesis of 3(S)-Carboxy-4(S)-hydroxy-2,3,4,5-tetrahydropyridazine, an Unusual Amino Acid Constituent of Luzopeptin A. [Erratum to document cited in CA111:39846] The Journal of Organic Chemistry. 60: 2950-2950. DOI: 10.1021/Jo00114A061  0.603
1995 Elbaum D, Porco JAJ, Stout TJ, Clardy J, Schreiber SL. Stereochemical and Conformational Effects on the Cycloaromatization of Dynemicin A-Related Molecules Journal of the American Chemical Society. 117: 211-225. DOI: 10.1021/Ja00106A025  0.666
1995 De Silva L, Herath W, Gunawardena D, Wijesundera R, Medis S, Choudhary M, Clardy J. Bisbynin, a novel secondary metabolite from the fungus Stachybotrys bisbyi (Srinivasan) Barron Tetrahedron Letters. 36: 1997-2000. DOI: 10.1016/0040-4039(95)00211-T  0.446
1995 Atta-ur-Rahman, Malik S, Hasan SS, Choudhary MI, Ni C, Clardy J. Nigellidine — A new indazole alkaloid from the seeds of Nigella sativa Tetrahedron Letters. 36: 1993-1996. DOI: 10.1016/0040-4039(95)00210-4  0.443
1994 Pcolinski MJ, Doskotch RW, Lee AY, Clardy J. Chlorosilphanol A and silphanepoxol, labdane diterpenes from Silphium perfoliatum. Journal of Natural Products. 57: 776-83. PMID 7931366 DOI: 10.1021/Np50108A014  0.337
1994 Holt DA, Luengo JI, Yamashita DS, Oh HJ, Konialian AL, Yen HK, Rozamus LW, Brandt M, Bossard MJ, Levy MA, Eggleston DS, Liang J, Schultz LW, Stout TJ, Clardy J. Design, Synthesis, And Kinetic Evaluation Of High-Affinity Fkbp Ligands And The X-Ray Crystal-Structures Of Their Complexes With Fkbp12. Journal of the American Chemical Society. 115: 9925-9938. DOI: 10.2210/Pdb1Fkg/Pdb  0.312
1994 Hayashi H, Mukaihara M, Murao S, Arai M, Lee AY, Clardy J. Acetoxydehydroaustin, a New Bioactive Compound, and Related Compound Neoaustin fromPenicilliumsp. MG–11 Bioscience, Biotechnology, and Biochemistry. 58: 334-338. DOI: 10.1271/Bbb.58.334  0.342
1994 Hallock YF, Manfredi KP, Blunt JW, Cardellina JH, Schaeffer M, Gulden K, Bringmann G, Lee AY, Clardy J. Korupensamines A-D, Novel Antimalarial Alkaloids from Ancistrocladus korupensis The Journal of Organic Chemistry. 59: 6349-6355. DOI: 10.1021/Jo00100A042  0.488
1994 Hemscheidt T, Puglisi MP, Larsen LK, Patterson GML, Moore RE, Rios JL, Clardy J. Structure and biosynthesis of borophycin, a new boeseken complex of boric acid from a marine strain of the blue-green alga Nostoc linckia The Journal of Organic Chemistry. 59: 3467-3471. DOI: 10.1021/Jo00091A042  0.332
1994 Yu J, Hu XE, Ho DK, Bean MF, Stephens RE, Cassady JM, Brinen LS, Clardy J. Absolute Stereochemistry of (+)-Gigantecin from Annona coriacea (Annonaceae) The Journal of Organic Chemistry. 59: 1598-1599. DOI: 10.1021/Jo00086A003  0.628
1994 Ikeda Y, Schultz LW, Clardy J, Schreiber SL. Structural basis for peptidomimicry by a natural product Journal of the American Chemical Society. 116: 4143-4144. DOI: 10.1021/Ja00088A086  0.303
1994 Bauer I, Maranda L, Shimizu Y, Peterson RW, Cornell L, Steiner JR, Clardy J. The Structures of Amphidinolide B Isomers: Strongly Cytotoxic Macrolides Produced by a Free-Swimming Dinoflagellate, Amphidinium sp Journal of the American Chemical Society. 116: 2657-2658. DOI: 10.1021/Ja00085A071  0.304
1994 Trischman JA, Tapiolas DM, Jensen PR, Dwight R, Fenical W, McKee TC, Ireland CM, Stout TJ, Clardy J. Salinamides A and B: anti-inflammatory depsipeptides from a marine streptomycete Journal of the American Chemical Society. 116: 757-758. DOI: 10.1021/Ja00081A042  0.694
1994 Atta-ur-Rahman, Ahmad S, Ali SS, Shah Z, Choudhary MI, Clardy J. New furanoid diterpenoidal constituents of Tinospora malabarica Tetrahedron. 50: 12109-12112. DOI: 10.1016/S0040-4020(01)89563-6  0.445
1994 Rodríguez J, Nieto RM, Hunter LM, Diaz MC, Crews P, Lobkovsky E, Clardy J. Variation among known kalihinol and new kalihinene diterpenes from the sponge Acanthella cavernosa Tetrahedron. 50: 11079-11090. DOI: 10.1016/S0040-4020(01)89411-4  0.335
1994 Yang X, Strobel G, Stierle A, Hess W, Lee J, Clardy J. A fungal endophyte-tree relationship: Phoma sp. in Taxus wallachiana Plant Science. 102: 1-9. DOI: 10.1016/0168-9452(94)90017-5  0.323
1994 Clardy J. Structural studies on FK-506, cyclosporin A and their immunophilin complexes Perspectives in Drug Discovery and Design. 2: 127-144. DOI: 10.1007/Bf02171740  0.311
1993 Miles DH, Tunsuwan K, Chittawong V, Hedin PA, Kokpol U, Ni CZ, Clardy J. Agrochemical activity and isolation of N-(4'-bromophenyl)-2,2-diphenylacetanilide from the Thai plant Arundo donax. Journal of Natural Products. 56: 1590-3. PMID 8254352 DOI: 10.1021/Np50099A020  0.329
1993 Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J. Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin Journal of Molecular Biology. 229: 105-124. PMID 7678431 DOI: 10.1006/Jmbi.1993.1012  0.709
1993 Hallock YF, Lu HSM, Clardy J, Strobel GA, Sugawara F, Samsoedin R, Yoshida S. Triticones, Spirocyclic Lactams from the Fungal Plant Pathogen Drechslera tritici-repentis Journal of Natural Products. 56: 747-754. DOI: 10.1021/Np50095A012  0.324
1993 Watanabe N, Yamamoto K, Ihshikawa H, Yagi A, Sakata K, Brinen LS, Clardy J. New Chlorophyll-A-Related Compounds Isolated as Antioxidants from Marine Bivalves Journal of Natural Products. 56: 305-317. DOI: 10.1021/Np50093A001  0.645
1993 Unson MD, Rose CB, Faulkner DJ, Brinen LS, Steiner JR, Clardy J. New polychlorinated amino acid derivatives from the marine sponge Dysidea herbacea The Journal of Organic Chemistry. 58: 6336-6343. DOI: 10.1021/Jo00075A029  0.659
1993 Midland SL, Keen NT, Sims JJ, Midland MM, Stayton MM, Burton V, Smith MJ, Mazzola EP, Graham KJ, Clardy J. The structures of syringolides 1 and 2, novel C-glycosidic elicitors from Pseudomonas syringae pv. tomato The Journal of Organic Chemistry. 58: 2940-2945. DOI: 10.1021/Jo00063A007  0.367
1993 Gupta S, Krasnoff SB, Renwick JAA, Roberts DW, Steiner JR, Clardy J. Viridoxins A and B: novel toxins from the fungus Metarhizium flavoviride Journal of Organic Chemistry. 58: 1062-1067. DOI: 10.1021/Jo00057A017  0.322
1993 Zheng GQ, Chang CJ, Stout TJ, Clardy J, Ho DK, Cassady JM. Ohioensins: novel benzonaphthoxanthenones from Polytrichum ohioense The Journal of Organic Chemistry. 58: 366-372. DOI: 10.1021/Jo00054A019  0.664
1993 Pathirana C, Fenical W, Corcoran E, Clardy J. Erythrodiene: A new spirobicyclic sesquiterpene of a rare skeletal class from the caribbean gorgonian coral Erythropodium caribaeorum Tetrahedron Letters. 34: 3371-3372. DOI: 10.1016/S0040-4039(00)79158-1  0.37
1993 Mantus EK, Clardy J. The synthesis of dithyreanitrile Tetrahedron Letters. 34: 1085-1086. DOI: 10.1016/S0040-4039(00)77496-X  0.774
1993 Shin J, Fenical W, Stout TJ, Clardy J. New cembradiene diterpenoids from an undescribed Caribbean gorgonian of the genus Eunicea Tetrahedron. 49: 515-524. DOI: 10.1016/S0040-4020(01)86256-6  0.69
1993 Corgiat JM, Scheuer PJ, Rios Steiner JL, Clardy J. Three pregnane-10,2-carbolactones from a sponge, Strongylophora sp Tetrahedron. 49: 1557-1562. DOI: 10.1016/S0040-4020(01)80343-4  0.327
1993 Yang X, Shimizu Y, Steiner JR, Clardy J. Nostoclide I and II, extracellular metabolites from a symbiotic cyanobacterium, Nostoc sp., from the lichen Peltigera canina. Tetrahedron Letters. 34: 761-764. DOI: 10.1016/0040-4039(93)89005-B  0.319
1993 Miles D, Tunsuwan K, Chittawong V, Kokpol U, Choudhary M, Clardy J. Boll weevil antifeedants from Arundo donax Phytochemistry. 34: 1277-1279. DOI: 10.1016/0031-9422(91)80015-S  0.378
1992 Ayer WA, Sun M, Browne LM, Brinen LS, Clardy J. Chemical investigation of the metabolites from the Canadian tuckahoe, Polyporus tuberaster. Journal of Natural Products. 55: 649-53. PMID 1517736 DOI: 10.1021/Np50083A015  0.665
1992 Fuller RW, Cardellina JH, Kato Y, Brinen LS, Clardy J, Snader KM, Boyd MR. A pentahalogenated monoterpene from the red alga Portieria hornemannii produces a novel cytotoxicity profile against a diverse panel of human tumor cell lines. Journal of Medicinal Chemistry. 35: 3007-11. PMID 1501227 DOI: 10.1021/Jm00094A012  0.633
1992 Liu Y, Ho DK, Cassady JM, Cottrell CE, Liang J, Clardy J, Cook VM, Baird WM. Dasytrichone, A Novel Flavone From Dasymaschalon Trichophorum With Cancer Chemopreventive Potential Natural Product Letters. 1: 161-165. DOI: 10.1080/10575639208048906  0.324
1992 McDonald LA, Foster MP, Phillips DR, Ireland CM, Lee AY, Clardy J. Tawicyclamides A and B, new cyclic peptides from the ascidian Lissoclinum patella: Studies on the solution- and solid-state conformations Journal of Organic Chemistry. 57: 4616-4624. DOI: 10.1021/Jo00043A017  0.558
1992 Gupta S, Krasnoff SB, Roberts DW, Renwick JAA, Brinen LS, Clardy J. Structure of efrapeptins from the fungus Tolypocladium niveum: peptide inhibitors of mitochondrial ATPase The Journal of Organic Chemistry. 57: 2306-2313. DOI: 10.1021/Jo00034A022  0.609
1992 Gunawardana GP, Koehn FE, Lee AY, Clardy J, He HY, Faulkner DJ. Pyridoacridine alkaloids from deep-water marine sponges of the family Pachastrellidae: structure revision of dercitin and related compounds and correlation with the kuanoniamines The Journal of Organic Chemistry. 57: 1523-1526. DOI: 10.1021/Jo00031A035  0.327
1992 Hagihara M, Anthony NJ, Stout TJ, Clardy J, Schreiber SL. Vinylogous polypeptides: an alternative peptide backbone Journal of the American Chemical Society. 114: 6568-6570. DOI: 10.1021/Ja00042A052  0.614
1992 Yamamoto K, Sakata K, Watanabe N, Yagi A, Brinen LS, Clardy J. Chlorophyllonic acid and methyl ester, a new chlorophyll a related compound isolated as an antioxidant from short-necked clam, ruditapes philippinarum Tetrahedron Letters. 33: 2587-2588. DOI: 10.1016/S0040-4039(00)92250-0  0.655
1992 de Silva ED, Miao S, Andersen RJ, Schultz LW, Clardy J. Trididemnic acids A and B, aromatic alkaloids from the northeastern pacific ascidian Trididemnum sp Tetrahedron Letters. 33: 2917-2920. DOI: 10.1016/S0040-4039(00)79560-8  0.351
1992 Kimura Y, Nishibe M, Nakajima H, Hamasaki T, Shigemitsu N, Sugawara F, Stout TJ, Clardy J. Emeniveol; A new pollen growth inhibitor from the fungus, Emericella nivea Tetrahedron Letters. 33: 6987-6990. DOI: 10.1016/S0040-4039(00)60913-9  0.673
1992 Leet JE, Golik J, Hofstead SJ, Matson JA, Lee AY, Clardy J. Kedarcidin chromophore: Structure elucidation of the amino sugar kedarosamine Tetrahedron Letters. 33: 6107-6110. DOI: 10.1016/S0040-4039(00)60018-7  0.323
1992 Atta-ur-Rahman, Habib N, Asif SE, Safdar A, Zahida I, Choudhary MI, Clardy J. Novel triterpenoids from the roots of Buxus papillosa Tetrahedron. 48: 3577-3584. DOI: 10.1016/S0040-4020(01)88495-7  0.468
1992 Kubo I, Ying B, Castillo M, Brinen LS, Clardy J. Podoandin, a molluscicidal sesquiterpene lactone from Podocarpus andina Phytochemistry. 31: 1545-1548. DOI: 10.1016/0031-9422(92)83103-6  0.661
1991 Ahmad VU, Choudhary MI, Akhtar MF, Ahmed M, Rizwani GH, Usmanghani K, Clardy J. 2-O-alpha-D-galactopyranosyl glycerol hexaacetate from Ruellia brittoniana. Journal of Natural Products. 53: 960-3. PMID 2095376 DOI: 10.1021/Np50070A028  0.393
1991 Powell RG, Mikolajczak KL, Zilkowski BW, Mantus EK, Cherry D, Clardy J. Limonoid antifeedants from seed of Sandoricum koetjape. Journal of Natural Products. 54: 241-6. PMID 2045819 DOI: 10.1021/Np50073A025  0.784
1991 Powell RG, Mikolajczak KL, Zilkowski BW, Lu HS, Mantus EK, Clardy J. Dithyreanitrile: an unusual insect antifeedant from Dithyrea wislizenii. Experientia. 47: 304-6. PMID 2009944 DOI: 10.1007/Bf01958168  0.794
1991 Atta-ur-Rahman, Alvi KA, Abbas SA, Sultana T, Shameel M, Choudhary MI, Clardy JC. A diterpenoid lactone from Aplysia juliana. Journal of Natural Products. 54: 886-8. PMID 1955886 DOI: 10.1021/Np50075A026  0.453
1991 Van Duyne GD, Standaert RF, Schreiber SL, Clardy J. Atomic structure of the rapamycin human immunophilin FKBP-12 complex Journal of the American Chemical Society. 113: 7433-7434. DOI: 10.2210/Pdb1Fkb/Pdb  0.592
1991 He HY, Faulkner DJ, Lu HSM, Clardy J. Norsesterterpene peroxides from the sponge Latrunculia sp Journal of Organic Chemistry. 56: 2112-2115. DOI: 10.1021/Jo00006A028  0.319
1991 Chikashita H, Porco JA, Stout TJ, Clardy J, Schreiber SL. Synthesis of the angular anthraquinone subunit of dynemicin A The Journal of Organic Chemistry. 56: 1692-1694. DOI: 10.1021/Jo00005A008  0.631
1991 Sugawara F, Strobel S, Strobel G, Larsen RD, Berglund DL, Gray G, Takahashi N, Coval SJ, Stout TJ, Clardy J. The structure and biological activity of cercosporamide from Cercosporidium henningsii The Journal of Organic Chemistry. 56: 909-910. DOI: 10.1021/Jo00003A002  0.66
1991 Tischler M, Andersen RJ, Choudhary MI, Clardy J. Terpenoids from the sponge Aplysilla glacialis and specimens of the nudibranch Cadlina luteomarginta found on the sponge The Journal of Organic Chemistry. 56: 42-47. DOI: 10.1021/Jo00001A010  0.359
1991 Tapiolas DM, Roman M, Fenical W, Stout TJ, Clardy J. Octalactins A and B: cytotoxic eight-membered-ring lactones from a marine bacterium, Streptomyces sp Journal of the American Chemical Society. 113: 4682-4683. DOI: 10.1021/Ja00012A048  0.647
1991 Raub MF, Cardellina JH, Choudhary MI, Ni CZ, Clardy J, Alley MC. Clavepictines A and B: cytotoxic quinolizidines from the tunicate Clavelina picta Journal of the American Chemical Society. 113: 3178-3180. DOI: 10.1021/Ja00008A060  0.359
1991 Lindquist NL, Fenical W, Duyne GDV, Clardy J. Isolation and structure determination of diazonamides A and B, unusual cytotoxic metabolites from the marine ascidian Diazona chinensis Journal of the American Chemical Society. 113: 2303-2304. DOI: 10.1021/Ja00006A060  0.337
1991 Gupta S, Krasnoff SB, Roberts DW, Renwick JAA, Brinen LS, Clardy J. Structures of the efrapeptins: potent inhibitors of mitochondrial ATPase from the fungus Tolypocladium niveum Journal of the American Chemical Society. 113: 707-709. DOI: 10.1021/Ja00002A068  0.61
1991 Shin-ya K, Furihata K, Hayakawa Y, Seto H, Kato Y, Clardy J. The structure of benthocyanin A. A new free radical scavenger of microbial origin Tetrahedron Letters. 32: 943-946. DOI: 10.1016/S0040-4039(00)92126-9  0.323
1991 Kigoshi H, Niwa H, Yamada K, Stout TJ, Clardy J. The three-dimensional structure of neohalicholactone, an unusual fatty acid metabolite from the marine sponge halichondria okadai kadota Tetrahedron Letters. 32: 2427-2428. DOI: 10.1016/S0040-4039(00)74344-9  0.668
1991 Gustafson KR, Munro MH, Blunt JW, Cardellina JH, McMahon JB, Gulakowski RJ, Cragg GM, Cox PA, Brinen LS, Clardy J, Boyd MR. HIV inhibitory natural products. 3. Diterpenes from and Tetrahedron. 47: 4547-4554. DOI: 10.1016/S0040-4020(01)86461-9  0.764
1991 Stout TJ, Clardy J, Charles Pathirana I, Penical W. Aplasmomycin c: Structural studies of a marine antibiotic Tetrahedron. 47: 3511-3520. DOI: 10.1016/S0040-4020(01)80865-6  0.672
1991 de Silva E, Racok JS, Andersen RJ, Allen TM, Brinen LS, Clardy J. Neamphine, a sulfur containing aromatic heterocycle isolated from the marine sponge neamphius huxleyi Tetrahedron Letters. 32: 2707-2710. DOI: 10.1016/0040-4039(91)85064-C  0.665
1991 Pathirana C, Dwight R, Jensen PR, Fenical W, Delgado A, Brinen LS, Clardy J. Structure and synthesis of a new butanolide from a marine actinomycete Tetrahedron Letters. 32: 7001-7004. DOI: 10.1016/0040-4039(91)85024-Y  0.663
1991 Spencer GF, Jones BE, Plattner RD, Barnekow DE, Brinen LS, Clardy J. A pterocarpan and two isoflavans from alfalfa Phytochemistry. 30: 4147-4149. DOI: 10.1016/0031-9422(91)83483-2  0.624
1991 Strobel G, Kenfield D, Bunkers G, Sugawara F, Clardy J. Phytotoxins as potential herbicides Experientia. 47: 819-826. DOI: 10.1007/Bf01922462  0.316
1990 Shin-ya K, Imai S, Furihata K, Hayakawa Y, Kato Y, Vanduyne GD, Clardy J, Seto H. Isolation and structural elucidation of an antioxidative agent, naphterpin. The Journal of Antibiotics. 43: 444-7. PMID 2351617 DOI: 10.7164/Antibiotics.43.444  0.311
1990 LaLonde RT, Perakyla H, Ishiguro Y, Clardy J, Brinen LS. Structure of an anhydride related to a mutagenic component of drinking water, 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone. Chemical Research in Toxicology. 3: 404-5. PMID 2133090  0.566
1990 Akee RK, Carroll TR, Yoshida WY, Scheuer PJ, Stout TJ, Clardy J. Two imidazole alkaloids from a sponge The Journal of Organic Chemistry. 55: 1944-1946. DOI: 10.1021/Jo00293A048  0.667
1990 Zabriskie TM, Foster MP, Stout TJ, Clardy J, Ireland CM. Studies on the solution- and solid-state structure of patellin 2 Journal of the American Chemical Society. 112: 8080-8084. DOI: 10.1021/Ja00178A035  0.727
1990 Porco JA, Schoenen FJ, Stout TJ, Clardy J, Schreiber SL. Transannular Diels-Alder route to systems related to dynemicin A Journal of the American Chemical Society. 112: 7410-7411. DOI: 10.1021/Ja00176A060  0.612
1990 Evans DA, Kaldor SW, Jones TK, Clardy J, Stout TJ. Total synthesis of the macrolide antibiotic cytovaricin Journal of the American Chemical Society. 112: 7001-7031. DOI: 10.1021/Ja00175A038  0.661
1990 Moore BS, Chen JL, Patterson GML, Moore RE, Brinen LS, Kato Y, Clardy J. [7.7]Paracyclophanes from blue-green algae Journal of the American Chemical Society. 112: 4061-4063. DOI: 10.1021/Ja00166A066  0.586
1990 Forsyth CJ, Clardy J. Total syntheses of (+)- and (-)-didemnenones A and B. Antiselectivity in the intramolecular carbomercuration reaction Journal of the American Chemical Society. 112: 3497-3505. DOI: 10.1021/Ja00165A038  0.509
1990 Fusetani N, Yasumuro K, Kawai H, Natori T, Brinen L, Clardy J. Kalihinene and isokalihinol B, cytotoxic diterpene isonitriles from the marine sponge Acanthella klethra Tetrahedron Letters. 31: 3599-3602. DOI: 10.1016/S0040-4039(00)94453-8  0.658
1990 West RR, Mayne CL, Ireland CM, Brinen LS, Clardy J. Plakinidines: Cytotoxic alkaloid pigments from the fijian sponge plakortis sp Tetrahedron Letters. 31: 3271-3274. DOI: 10.1016/S0040-4039(00)89041-3  0.716
1990 Aknin M, Miralles J, Kornprobst J, Faure R, Gaydou E, Boury-Esnault N, Kato Y, Clardy J. Trikentramine, an unusual pyrrole derivative from the sponge trikentrion loeve carter Tetrahedron Letters. 31: 2979-2982. DOI: 10.1016/S0040-4039(00)89003-6  0.304
1990 Wiemer DF, K. Wolfe L, Fenical W, Strobel SA, Clardy J. Palmosalides A-C, new sesquiterpenoids from the indian ocean telestacean octocoral Coelogorgia palmosa Tetrahedron Letters. 31: 1973-1976. DOI: 10.1016/S0040-4039(00)88892-9  0.33
1990 Coval SJ, Hradil CM, Lu HS, Clardy J, Satouri S, Strobel GA. Pyrenoline-A and -B, two new phytotoxins from Pyrenophora teres Tetrahedron Letters. 31: 2117-2120. DOI: 10.1016/0040-4039(90)80086-2  0.308
1990 Long-Ze L, Cordell GA, Chao-Zhou N, Clardy J. Two oxindole alkaloids from Gelsemium elegans Phytochemistry. 29: 3013-3017. DOI: 10.1016/0031-9422(90)87125-E  0.34
1990 Ahmad VU, Qazi S, Zia NB, Xu C, Clardy J. Cleocarpone, a triterpenoid from Cleome brachycarpa Phytochemistry. 29: 670-672. DOI: 10.1016/0031-9422(90)85144-5  0.352
1989 Coll JC, Bowden BF, Heaton A, Scheuer PJ, Li MK, Clardy J, Schulte GK, Finer-Moore J. Structures and possible functions of epoxypukalide and pukalide : Diterpenes associated with eggs of sinularian soft corals (Cnidaria, Anthozoa, Octocorallia, Alcyonacea, Alcyoniidae). Journal of Chemical Ecology. 15: 1177-91. PMID 24272003 DOI: 10.1007/Bf01014821  0.308
1989 Lin LZ, Cordell GA, Ni CZ, Clardy J. New humantenine-type alkaloids from Gelsemium elegans. Journal of Natural Products. 52: 588-94. PMID 2778451 DOI: 10.1021/Np50063A019  0.327
1989 Nishio M, Tomatsu K, Konishi M, Tomita K, Oki T, Kawaguchi H, Clardy J. Karnamicin, a complex of new antifungal antibiotics. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties. The Journal of Antibiotics. 42: 852-68. PMID 2661511 DOI: 10.7164/Antibiotics.42.852  0.34
1989 Ayer WA, Craw PA, Stout TJ, Clardy J. Novel sesquiterpenoids from the fairy ring fungus, Marasmiusoreades Canadian Journal of Chemistry. 67: 773-778. DOI: 10.1139/V89-116  0.683
1989 Manker DC, Faulkner DJ, Stout TJ, Clardy J. The baconipyrones. Novel polypropionates from the pulmonate Siphonaria baconi The Journal of Organic Chemistry. 54: 5371-5374. DOI: 10.1021/Jo00283A036  0.636
1989 Hughes P, Clardy J. Total synthesis of 3(S)-carboxy-4(S)-hydroxy-2,3,4,5-tetrahydropyridazine, an unusual amino acid constituent of luzopeptin A The Journal of Organic Chemistry. 54: 3260-3264. DOI: 10.1021/Jo00275A007  0.595
1989 Zheng GQ, Chang CJ, Stout TJ, Clardy J, Cassady JM. Ohioensin-A: a novel benzonaphthoxanthenone from Polytrichum ohioense Journal of the American Chemical Society. 111: 5500-5501. DOI: 10.1021/Ja00196A085  0.606
1989 Dumdei EJ, De Silva ED, Andersen RJ, Choudhary MI, Clardy J. Chromodorolide A, a rearranged diterpene with a new carbon skeleton from the Indian Ocean nudibranch Chromodoris cavae Journal of the American Chemical Society. 111: 2712-2713. DOI: 10.1021/Ja00189A055  0.372
1989 Atta-ur-Rahman, Alvi KA, Abbas SA, Choudhary MI, Clardy J. Zoanthaminone, a new alkaloid from a marine zoanthid Tetrahedron Letters. 30: 6825-6828. DOI: 10.1016/S0040-4039(01)93362-3  0.466
1989 Jogia MK, Andersen RJ, Mantus EK, Clardy J. Dysoxysulfone, a sulfur rich metabolite from the Fijian medicinal plant dysoxylum richii Tetrahedron Letters. 30: 4919-4920. DOI: 10.1016/S0040-4039(01)80542-6  0.786
1989 Kimura Y, Nakajima H, Hamasaki T, Sugawara F, Parkanyi L, Clardy J. Pinthunamide, a new tricyclic sesquiterpene amide produced by a fungus, Ampullifernia sp Tetrahedron Letters. 30: 1267-1270. DOI: 10.1016/S0040-4039(00)72732-8  0.344
1989 Kushlan DM, Faulkner DJ, Parkanyi L, Clardy J. Metabolites of the Palauan sponge dactylospongia sp. Tetrahedron. 45: 3307-3312. DOI: 10.1016/S0040-4020(01)81009-7  0.327
1989 Kenfield D, Hallock Y, Clardy J, Strobel G. Curvulin and O-Methylcurvulinic acid: Phytotoxic metabolites of Drechslera indica which cause necroses on purslane and spiny amaranth Plant Science. 60: 123-127. DOI: 10.1016/0168-9452(89)90052-6  0.33
1989 Hradil CM, Hallock YF, Clardy J, Kenfield DS, Strobel G. Phytotoxins from Alternaria cassiae Phytochemistry. 28: 73-75. DOI: 10.1016/0031-9422(89)85011-3  0.301
1988 Tischler M, Ayer SW, Andersen RJ, Mitchell JF, Clardy J. Anthosterones A and B, ring A contracted steroids from the sponge Anthoracuata graceae Canadian Journal of Chemistry. 66: 1173-1178. DOI: 10.1139/V88-192  0.336
1988 Cooray NM, Scheuer PJ, Parkanyi L, Clardy J. Shermilamine A: A Pentacyclic Alkaloid from a Tunicate Journal of Organic Chemistry. 53: 4619-4620. DOI: 10.1021/Jo00254A049  0.313
1988 Roll DM, Ireland CM, Lu HSM, Clardy J. Fascaplysin, an unusual antimicrobial pigment from the marine sponge Fascaplysinopsis sp Journal of Organic Chemistry. 53: 3276-3278. DOI: 10.1021/Jo00249A025  0.529
1988 Lindquist NL, Fenical W, Sesin DF, Ireland CM, Duyne GDV, Forsyth CJ, Clardy J. Isolation and structure determination of the didemnenones, novel cytotoxic metabolites from tunicates Journal of the American Chemical Society. 110: 1308-1309. DOI: 10.1021/Ja00212A059  0.581
1988 Seto H, Otake N, Sato S, Yamaguchi H, Takada K, Itoh M, Lu HS, Clardy J. The structure of a new nucleoside antibiotic, capuramycin Tetrahedron Letters. 29: 2343-2346. DOI: 10.1016/S0040-4039(00)86055-4  0.358
1988 Gulavita N, Hori A, Shimizu Y, Laszlo P, Clardy J. Aphanorphine, a novel tricyclic alkaloid from the blue-green algaAphanizomenon flos-aquae Tetrahedron Letters. 29: 4381-4384. DOI: 10.1016/S0040-4039(00)80500-6  0.319
1988 Atta-ur-Rahman, Ahmad S, Rycroft DS, Párkányi L, Choudhary MI, Clardy J. Malabarolide, a novel furanoid bisnorditerpenoid from Tinospora malabarica Tetrahedron Letters. 29: 4241-4244. DOI: 10.1016/S0040-4039(00)80464-5  0.434
1988 Fahy E, Molinski TF, Harper MK, Sullivan BW, Faulkner DJ, Parkanyi L, Clardy J. Haliclonadiamine, an antimicrobial alkaloid from the sponge Haliclona SP Tetrahedron Letters. 29: 3427-3428. DOI: 10.1016/0040-4039(88)85180-3  0.57
1988 Atta-Ur-Rahman, Ahmad VU, Bano S, Abbas SA, Alvi KA, Ali MS, Lu HM, Clardy J. Pinnatazane, a bridged cyclic ether sesquiterpene from Laurencia pinnatifida Phytochemistry. 27: 3879-3880. DOI: 10.1016/0031-9422(88)83036-X  0.327
1988 LINDQUIST N, FENICAL W, SESIN DF, IRELAND CM, VAN DUYNE GD, FORSYTH CJ, CLARDY J. ChemInform Abstract: Isolation and Structure Determination of the Didemnenones, A-D ((Ia), (Ib), (II), (III)), Novel Cytotoxic Metabolites from Tunicates Cheminform. 19. DOI: 10.1002/chin.198823347  0.628
1988 Lindquist N, Fenical W, Sesin DF, Ireland CM, Van Duyne GD, Forsyth CJ, Clardy J. Isolation and structure determination of the didemnenones, novel cytotoxic metabolites from tunicates Journal of the American Chemical Society. 110: 1308-1309.  0.763
1987 Ayer WA, Hoyano Y, Pedras MS, Clardy J, Arnold E. Metabolites produced by the scleroderris canker fungus, Gremmeniellaabietina. Part 2. The structure of scleroderolide Canadian Journal of Chemistry. 65: 748-753. DOI: 10.1139/V87-127  0.321
1987 Clardy J, Duyne GV, González AG, Manta E, Martín JD, Pérez C, Ravelo JL, Schulte GK. A new tricarbocyclic diterpene with a novel carbon skeleton from a marine alga Journal of the Chemical Society, Chemical Communications. 767-768. DOI: 10.1039/C39870000767  0.326
1987 Golik J, Clardy J, Dubay G, Groenewold G, Kawaguchi H, Konishi M, Krishnan B, Ohkuma H, Saitoh KI, Doyle TW. Esperamicins, a novel class of potent antitumor antibiotics. 2. Structure of esperamicin X Journal of the American Chemical Society. 109: 3461-3462. DOI: 10.1021/Ja00245A048  0.328
1987 Bittner M, Gonzalez F, Valdebenito H, Silva M, Paul VJ, Fenical W, Chen MHM, Clardy J. A novel tetracyclic polyketal from the marine red alga Tetrahedron Letters. 28: 4031-4032. DOI: 10.1016/S0040-4039(01)83853-3  0.338
1987 Cardellina JH, Hendrickson RL, Manfredi KP, Strobel SA, Clardy J. Bissetone, a unique antimicrobial pyranone from the gorgonian Briareu polyanthes Tetrahedron Letters. 28: 727-730. DOI: 10.1016/S0040-4039(01)80973-4  0.339
1987 Clardy J, Van Duyne G, Gallardo A, Manta E, Martín JD, Pérez C, Pérez R, L. Ravelo J, Rodríguez*b ML, Schulte GK. A new diterpene with two polymorphic modifications from a marine alga Tetrahedron Letters. 28: 6699-6700. DOI: 10.1016/S0040-4039(00)96949-1  0.31
1987 San-Martín A, Rovirosa J, Xu C, Lu HS, Clardy J. Further structural studies on the 2-methyl-3(2H)-furanone derived metabolites of the marine alga Laurencia chilensis Tetrahedron Letters. 28: 6013-6014. DOI: 10.1016/S0040-4039(00)96850-3  0.318
1987 Sakata K, Maruyama M, Uzawa J, Sakurai A, Lu HS, Clardy J. Structural revision of aspirochlorine (=antibiotic A30641), a novel epidithiopiperazine-2, 5-dione produced byaspergillus SPP. Tetrahedron Letters. 28: 5607-5610. DOI: 10.1016/S0040-4039(00)96792-3  0.338
1987 Kobayashi J, Cheng J, Ishibashi M, Nakamura H, Ohizumi Y, Hirata Y, Sasaki T, Lu H, Clardy J. Prianosin A, a novel antileukemic alkaloid from the okinawan marine sponge Prianos melanos Tetrahedron Letters. 28: 4939-4942. DOI: 10.1016/S0040-4039(00)96664-4  0.333
1987 Williams DE, Andersen RJ, Parkanyi L, Clardy J. Gersolide, a diterpenoid with a new rearranged carbon skeleton from the soft coral Gersemia rubiformis Tetrahedron Letters. 28: 5079-5080. DOI: 10.1016/S0040-4039(00)95594-1  0.32
1987 Seto H, Furihata K, Saeki K, Otake N, Kusakabe Y, Xu C, Clardy J. Structural studies of natural products by new nmr techniques. The structure of a new polyether antibiotic, portmicin Tetrahedron Letters. 28: 3357-3360. DOI: 10.1016/S0040-4039(00)95511-4  0.346
1986 Smitka TA, Bunge RH, Wilton JH, Hokanson GC, French JC, He CH, Clardy J. PD 116,152, a new phenazine antitumor antibiotic structure and antitumor activity Journal of Antibiotics. 39: 800-803. PMID 3755428 DOI: 10.7164/Antibiotics.39.800  0.354
1986 Montelione GT, Hughes P, Clardy J, Scheraga HA. Conformational properties of 2,4-methanoproline (2-carboxy-2,4-methanopyrrolidine) in peptides: determination of preferred peptide bond conformation in aqueous solution by proton Overhauser measurements Journal of the American Chemical Society. 108: 6765-6773. DOI: 10.1021/Ja00281A051  0.592
1986 Zabriskie TM, Klocke JA, Ireland CM, Marcus AH, Molinski TF, Faulkner DJ, Xu C, Clardy JC. Jaspamide, a modified peptide from a Jaspis sponge, with insecticidal and antifungal activity Journal of the American Chemical Society. 108: 3123-3124. DOI: 10.1021/Ja00271A062  0.624
1986 Naengchomnong W, Thebtaranonth* Y, Wiriyachitra P, Okamoto K, Clardy* J. Isolation and structure determination of two novel Lathyrenes from Jatropha Curcus Tetrahedron Letters. 27: 5675-5678. DOI: 10.1016/S0040-4039(00)85298-3  0.351
1986 Schiehser GA, White JD, Matsumoto G, Pezzanite JO, Clardy J. The structure of leptosphaerin Tetrahedron Letters. 27: 5587-5590. DOI: 10.1016/S0040-4039(00)85272-7  0.337
1986 Gerwick WH, Lopez A, Van Duyne GD, Clardy J, Ortiz W, Baez A. Hormothamnione, a novel cytotoxic styrylchromone from the marine cyanophyte hormothamnion enteromorphoides grunow Tetrahedron Letters. 27: 1979-1982. DOI: 10.1016/S0040-4039(00)84426-3  0.637
1986 Fang S, Xiao-tian L, Dequan Y, Chang-fu X, Clardy J. The Structures of Spirasine V and Spirasine VI. Tetrahedron Letters. 27: 275-278. DOI: 10.1016/S0040-4039(00)83995-7  0.319
1986 Clardy J. X-ray Diffraction and Marine Natural Products Studies in Organic Chemistry. 26: 90-107. DOI: 10.1007/978-3-642-71425-2_5  0.335
1986 ZABRISKIE TM, KLOCKE JA, IRELAND CM, MARCUS AH, MOLINSKI TF, FAULKNER DJ, XU C, CLARDY JC. ChemInform Abstract: Jaspamide (I), a Modified Peptide from a Jaspis Sponge, with Insecticidal and Antifungal Activity. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198640306  0.499
1985 Sugawara F, Strobel G, Fisher LE, Van Duyne GD, Clardy J. Bipolaroxin, a selective phytotoxin produced by Bipolaris cynodontis. Proceedings of the National Academy of Sciences of the United States of America. 82: 8291-4. PMID 3866223 DOI: 10.1073/Pnas.82.24.8291  0.628
1985 González AG, Martín JD, Martín VS, Pérez R, Tagle B, Clardy J. Rhodolaureol and rhodolauradiol, two new halogenated tricyclic sesquiterpenes from a marine alga Journal of the Chemical Society, Chemical Communications. 260-261. DOI: 10.1039/C39850000260  0.348
1985 Roll DM, Chang CWJ, Scheuer PJ, Gray GA, Shoolery JN, Matsumoto GK, Van Duyne GD, Clardy J. Structure of the psammaplysins Journal of the American Chemical Society. 107: 2916-2920. DOI: 10.1021/Ja00296A014  0.615
1985 Montelione G, Arnold E, Meinwald Y, Stimson E, Denton J, Huang S, Clardy J, Scheraga H. Additions and Corrections - Chain-Folding Initiation Structures in Ribonuclease A: Conformational Analysis of trans-Ac-Asn-Pro-Tyr NHMe and trans-Ac-Tyr-Pro-Asn-NHMe in Water and in the Solid State Journal of the American Chemical Society. 107: 1457-1457. DOI: 10.1021/Ja00291A602  0.469
1985 Chou H, Shimizu Y, Van Duyne G, Clardy J. Isolation and structures of two new polycyclic ethers from gymnodinium breve davis (=ptychodiscus brevis) Tetrahedron Letters. 26: 2865-2868. DOI: 10.1016/S0040-4039(00)98857-9  0.348
1985 Gustafson K, Andersen RJ, Cun-heng H, Clardy J. Marginatafuran. a furanoditerpene with a new carbon skeleton from the dorid nudibranch Tetrahedron Letters. 26: 2521-2524. DOI: 10.1016/S0040-4039(00)98826-9  0.324
1985 Atta-ur-Rahman, Malik S, Cun-heng H, Clardy J. Isolation and structure determination of nigellicine, a novel alkaloid from the seeds of Tetrahedron Letters. 26: 2759-2762. DOI: 10.1016/S0040-4039(00)94904-9  0.331
1985 Groweiss A, Fenical W, Cun-heng H, Clardy J, Zhongde W, Zhongnian Y, Kanghou L. Subergorgic acid, a novel tricyclopentanoid cardiotoxin from the pacific gorgonian coral Tetrahedron Letters. 26: 2379-2382. DOI: 10.1016/S0040-4039(00)94832-9  0.315
1985 Nettleton D, Doyle T, Krishnan B, Matsumoto G, Clardy J. Isolation and structure of rebeccamycin - a new antitumor antibiotic from nocardia aerocoligenes Tetrahedron Letters. 26: 4011-4014. DOI: 10.1016/S0040-4039(00)89280-1  0.356
1985 Sato A, Fenical W, Qi-tai Z, Clardy J. Norcembrene diterpenoids from pacific soft-corals of the genus sinularia (Alcyonacea; octocorallia) Tetrahedron. 41: 4303-4308. DOI: 10.1016/S0040-4020(01)97201-1  0.361
1985 Yasumoto T, Murata M, Oshima Y, Sano M, Matsumoto G, Clardy J. Diarrhetic shellfish toxins Tetrahedron. 41: 1019-1025. DOI: 10.1016/S0040-4020(01)96469-5  0.304
1985 Ahmad VU, Amber A, Arif S, Chen MH, Clardy J. Cadabicine, an alkaloid from Cadaba farinosa Phytochemistry. 24: 2709-2711. DOI: 10.1016/S0031-9422(00)80700-1  0.342
1985 Semmelhack MF, Harrison JJ, Young DC, Gutierrez A, Rafii S, Clardy J. [3.3]Metacyclophane: a novel synthesis and a study of the structure through x-ray diffraction, molecular mechanics, and solution NMR analysis Journal of the American Chemical Society. 107: 7508-7514. DOI: 10.1002/Chin.198613169  0.314
1985 WALKER RP, ROSSER RM, FAULKNER DJ, BASS LS, HE C, CLARDY J. ChemInform Abstract: Two Steroidal Alkaloids from a Marine Sponge, Plakina sp. Two New Metabolites of the Sponge Dysidea amblia and Revision of the Structure of Ambliol B. Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198528354  0.327
1985 MONTELIONE GT, ARNOLD E, MEINWALD YC, STIMSON ER, DENTON JB, HUANG S, CLARDY J, SCHERAGA HA. ChemInform Abstract: Chain-Folding Initiation Structures in Ribonuclease A: Conformational Analysis of trans-Ac-Asn-Pro-Tyr-NHMe (I) und trans-Ac-Tyr-Pro-Asn-NHMe (II) in Water und in the Solid State. Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198515079  0.468
1984 Flegel TW, Meevootisom V, Thebtaranonth Y, Qi-Tai Z, Clardy J. A new naphthaquinone antibiotic from a new species of yeast. The Journal of Antibiotics. 37: 325-9. PMID 6725143 DOI: 10.7164/Antibiotics.37.325  0.322
1984 Lang H, Shouzhen L, McCabe T, Clardy J. A new monoterpene glycoside of Paeonia lactiflora. Planta Medica. 50: 501-504. PMID 6531410 DOI: 10.1055/S-2007-969783  0.305
1984 Gonzalez AG, Martin JD, Martin VS, Perez R, Drexler SA, Clardy J. Structure Of Güimarediol, A New Rearranged Sesquiterpenoid From The Red Alga Laubencia Sp. Chemistry Letters. 13: 1865-1866. DOI: 10.1246/Cl.1984.1865  0.345
1984 Gonzalez AG, Martin JD, Perez C, Rovirosa J, Tagle B, Clardy J. ISOLATION AND X-RAY STRUCTURAL DETERMINATION OF THREE NEW DITERPENOIDS FROM THE MARINE ALGATAONIA ATOMARIA Chemistry Letters. 13: 1649-1652. DOI: 10.1246/Cl.1984.1649  0.345
1984 Douglas JL, Martel A, Caron G, Ménard M, Silveira L, Clardy J. Nuclear analogs of β-lactam antibiotics. XX. Synthesis and X-ray structure determination of exocyclic penems: sulfur analogs of clavulanic acid Canadian Journal of Chemistry. 62: 2282-2286. DOI: 10.1139/V84-388  0.337
1984 Walker RP, Rosser RM, Faulkner DJ, Bass LS, He CH, Clardy J. Two new metabolites of the sponge Dysidea amblia and revision of the structure of ambliol B The Journal of Organic Chemistry. 49: 5160-5163. DOI: 10.1021/Jo00200A030  0.311
1984 Rao CB, Anjaneyula ASR, Sarma NS, Venkatateswarlu Y, Rosser RM, Faulkner DJ, Chen MHM, Clardy J. Zoanthamine; a novel alkaloid from a marine zoanthid Journal of the American Chemical Society. 106: 7983-7984. DOI: 10.1021/Ja00337A062  0.316
1984 Montelione GT, Arnold E, Meinwald YC, Stimson ER, Denton JB, Huang SG, Clardy J, Scheraga HA. Chain-folding initiation structures in ribonuclease A: conformational analysis of trans-Ac-Asn-Pro-Tyr-NHMe and trans-Ac-Tyr-Pro-Asn-NHMe in water and in the solid state Journal of the American Chemical Society. 106: 7959-7969. DOI: 10.1021/Ja00337A052  0.468
1984 Gustafson K, Andersen RJ, Chen MH, Clardy J, Hochlowski JE. Terpenoic acid glycerides from the dorid nudibranch Tetrahedron Letters. 25: 11-14. DOI: 10.1016/S0040-4039(01)91135-9  0.305
1984 Nakatsu T, John Faulkner D, Matsumoto GK, Clardy J. Structure of the diterpene portion of a novel base from the sponge Agelas mauritiana Tetrahedron Letters. 25: 935-938. DOI: 10.1016/S0040-4039(01)80066-6  0.347
1984 Hufford CD, Oguntimein B, Martin M, Clardy J. Syncarpurea, a novel metabolite from Tetrahedron Letters. 25: 371-374. DOI: 10.1016/S0040-4039(00)99886-1  0.358
1984 Coval SJ, Scheuer PJ, Matsumoto GK, Clardy J. Two new xenicin diterpenoids from the octocoral anthelia edmondsoni Tetrahedron. 40: 3823-3828. DOI: 10.1016/S0040-4020(01)88813-X  0.34
1983 San Martin A, Rovirosa J, Muñoz O, Chen MH, Guneratne RD, Clardy J. The isolation and structure determination of chilenone A, a putative dimer of 2-methyl-3(2H)-furanone from the marine alga Tetrahedron Letters. 24: 4063-4066. DOI: 10.1016/S0040-4039(00)88262-3  0.343
1983 Liu J, Huang M, Arnold GF, Arnold E, Clardy J, Ayer WA. Schisanlactone A, a new type of triterpenoid from a . Tetrahedron Letters. 24: 2351-2354. DOI: 10.1016/S0040-4039(00)81922-X  0.355
1983 González A, Martín J, Norte M, Pérez R, Weyler V, Rafii S, Clardy J. A new diterpene fromAplysia dactylomela Tetrahedron Letters. 24: 1075-1076. DOI: 10.1016/S0040-4039(00)81608-1  0.34
1982 Cardellina II JH, Horsley SB, Clardy J, Leftow SR, Meinwald J. Secondary metabolites from the red alga Laurenciaintricata: halogenated enynes Canadian Journal of Chemistry. 60: 2675-2677. DOI: 10.1139/V82-384  0.354
1982 Pettit GR, Herald CL, Doubek DL, Herald DL, Arnold E, Clardy J. Isolation and structure of bryostatin 1 Journal of the American Chemical Society. 104: 6846-6848. DOI: 10.1021/Ja00388A092  0.327
1982 Howard BM, Fenical W, Donovan SE, Clardy J. Neoirieone, a diterpenoid of a new skeletal class from the red marine alga Laurencia cf. Irieii Tetrahedron Letters. 23: 3847-3850. DOI: 10.1016/S0040-4039(00)87724-2  0.336
1982 Izac RR, Poet SE, Fenical W, Engen DV, Clardy J. The structure of pacifigorgiol, an ichthyotoxic sesquiterpenoid from the pacific gorgonian coral Tetrahedron Letters. 23: 3743-3746. DOI: 10.1016/S0040-4039(00)87695-9  0.34
1982 Paul VJ, Fenical W, Raffii S, Clardy J. The isolation of new norcycloartene triterpenoids from the tropical marine alga (chlorophyta) Tetrahedron Letters. 23: 3459-3462. DOI: 10.1016/S0040-4039(00)87641-8  0.36
1982 McCabe T, Clardy J, Minale L, Pizza C, Zollo F, Riccio R. A triterpenoid pigment with the isomalabaricane skeleton from the marine sponge . Tetrahedron Letters. 23: 3307-3310. DOI: 10.1016/S0040-4039(00)87601-7  0.349
1982 Kikuchi H, Tsukitani Y, Yamada Y, Iguchi K, Drexler SA, Clardy J. Lemnalol, a new sesquiterpenoid from the soft coral Verseveldt Tetrahedron Letters. 23: 1063-1066. DOI: 10.1016/S0040-4039(00)87022-7  0.347
1982 González AG, Martín JD, Martín VS, Norte M, Pérez R, Ruano JZ, Drexler SA, Clardy J. Non-terpenoid C-15 metabolites from the red seaweed Laurencia pinnatifida Tetrahedron. 38: 1009-1014. DOI: 10.1016/0040-4020(82)85080-1  0.302
1982 Bandurraga MM, McKittrick B, Fenical W, Arnold E, Clardy J. Diketone cembrenolides from the pacific gorgonian lophogorgia alba Tetrahedron. 38: 305-310. DOI: 10.1016/0040-4020(82)80012-4  0.335
1981 Balitz DM, O'Herron FA, Bush J, Vyas DM, Nettleton DE, Grulich RE, Bradner WT, Doyle TW, Arnold E, Clardy J. Antitumor agents from Streptomyces anandii: gilvocarcins V, M and E. The Journal of Antibiotics. 34: 1544-55. PMID 7344705 DOI: 10.7164/Antibiotics.34.1544  0.49
1981 Miller RW, Powell RG, Smith CR, Arnold E, Clardy J. Antileukemic alkaloids from Taxus wallichiana Zucc Journal of Organic Chemistry. 46: 1469-1474. DOI: 10.1021/Jo00320A045  0.314
1981 Lin Y, Risk M, Ray SM, Van Engen D, Clardy J, Golik J, James JC, Nakanishi K. Isolation and structure of brevetoxin B from the "red tide" dinoflagellate Ptychodiscus brevis (Gymnodinium breve) Journal of the American Chemical Society. 103: 6773-6775. DOI: 10.1021/Ja00412A053  0.308
1981 Izac RR, Fenical W, Tagle B, Clardy J. Neolemnane and eremophilane sesquiterpenoids from the pacific soft coral lemnalia africana Tetrahedron. 37: 2569-2573. DOI: 10.1016/S0040-4020(01)98958-6  0.367
1981 Sun HH, McConnell OJ, Fenical W, Hirotsu K, Clardy J. Tricyclic diterpenoids of the dolastane ring system from the marine alga dictyota divaricata Tetrahedron. 37: 1237-1242. DOI: 10.1016/S0040-4020(01)92057-5  0.342
1981 Ayer WA, Saeedi-Ghomi MH, Engen DV, Tagle B, Clardy J. The sterpuric acids Tetrahedron. 37: 379-385. DOI: 10.1016/0040-4020(81)85074-0  0.301
1981 Clardy J, Finer-Moore J, Weiler L, Wiley DC. The structure of acumycin Tetrahedron. 37: 91-97. DOI: 10.1016/0040-4020(81)85044-2  0.32
1981 Miller RW, Powell RG, Smith CRJ, Arnold EV, Clardy J. Antileukemic Alkaloids From Taxus Wallichiana Zucc Cheminform. 12. DOI: 10.1002/Chin.198133330  0.306
1980 Wiemer DF, Meinwald J, Prestwich GD, Solheim BA, Clardy J. Biflora-4,10(19),15-triene: A new diterpene from a termite soldier (isoptera termitidae termitinae) [1] Journal of Organic Chemistry. 45: 191-192. DOI: 10.1021/Jo01289A048  0.337
1980 Gerwick WH, Fenical W, Van Engen D, Clardy J. Isolation and structure of spatol, a potent inhibitor of cell replication from the brown seaweed Spatoglossum schmittii Journal of the American Chemical Society. 102: 7991-7993. DOI: 10.1021/Ja00547A055  0.319
1980 Bajaj AG, Dev S, Tagle B, Telser J, Clardy J. The stereochemistry of allohimachalol Tetrahedron Letters. 21: 325-326. DOI: 10.1016/S0040-4039(01)85463-0  0.52
1980 Gallagher RT, McCabe T, Hirotsu K, Clardy J, Nicholson J, Wilson BJ. Aflavinine, a novel indole-mevalonate metabolite from tremorgen-producing species Tetrahedron Letters. 21: 243-246. DOI: 10.1016/S0040-4039(00)71179-8  0.329
1980 Gallagher RT, Clardy J, Wilson BJ. Aflatrem, a tremorgenic toxin from Aspergillus flavus Tetrahedron Letters. 21: 239-242. DOI: 10.1016/S0040-4039(00)71178-6  0.301
1980 Hughes P, Martin M, Clardy J. Synthesis of 2,4-methanoproline Tetrahedron Letters. 21: 4579-4580. DOI: 10.1016/0040-4039(80)80078-5  0.616
1980 Toth JA, Jay Burreson B, Scheuer PJ, Finer-Moore J, Clardy J. Emblide, a new polyfunctional cembranolide from the soft coral sarcophyton glaucum Tetrahedron. 36: 1307-1309. DOI: 10.1016/0040-4020(80)85041-1  0.311
1980 Howard BM, Schulte GR, Fenical W, Solheim B, Clardy J. Three new vinyl acetylenes from the marine red alga laurencia Tetrahedron. 36: 1747-1751. DOI: 10.1016/0040-4020(80)80069-X  0.38
1980 Howard BM, Fenical W, Hirotsu K, Solheim B, Clardy J. The rhodophytin and chondriol natural products; structures of several new acetylenes from laurencia, and a reassignment of structure for cis-rhodophytin Tetrahedron. 36: 171-176. DOI: 10.1016/0040-4020(80)80003-2  0.324
1980 Kashman Y, Bodner M, Finer-Moore JS, Clardy J. Δ 9(15)-Africanene, a new sesquiterpene hydrocarbon from the soft coralSinularia erecta Experientia. 36: 891-892. DOI: 10.1007/Bf01953775  0.338
1980 CARDLLINA JHI, MOORE RE, ARNOLD EV, CLARDY J. ChemInform Abstract: STRUCTURE AND ABSOLUTE CONFIGURATION OF MALYNGOLIDE, AN ANTIBIOTIC FROM THE MARINE BLUE-GREEN ALGA LYNGBYA MAJUSCULA GOMONT Chemischer Informationsdienst. 11. DOI: 10.1002/Chin.198012369  0.329
1979 Cardellina JH, Moore RE, Arnold EV, Clardy J. Structure and absolute configuration of malyngolide, an antibiotic from the marine blue-green alga Lyngbya majuscula Gomont The Journal of Organic Chemistry. 44: 4039-4042. DOI: 10.1021/Jo01337A003  0.327
1979 Powell RG, Smith CR, Weisleder D, Muthard DA, Clardy J. Sesbanine, a novel cytotoxic alkaloid from Sesbania drummondii Journal of the American Chemical Society. 101: 2784-2785. DOI: 10.1021/Ja00504A074  0.304
1979 Ireland C, Faulkner DJ, Finer JS, Clardy J. Crispatone, a metabolite of the opisthobranch mollusc Tridachia crispata Journal of the American Chemical Society. 101: 1275-1276. DOI: 10.1021/Ja00499A037  0.508
1979 Cimino G, De Stefano S, Minale L, Riccio R, Hirtosu K, Clardy J. Two novel sesterterpene hydroxyquinols from the sponge Tetrahedron Letters. 20: 3619-3622. DOI: 10.1016/S0040-4039(01)95479-6  0.319
1979 Holbert GW, Ganem B, Van Engen D, Clardy J, Borsub L, Chantrapromma K, Sadavongvivad C, Thebtaranonth Y. Shikimate-derived metabolites revised structure and total synthesis of pipoxide Tetrahedron Letters. 20: 715-718. DOI: 10.1016/S0040-4039(01)93554-3  0.328
1979 McIntyre DE, Faulkner D, Van Engen D, Clardy J. Renierone, an antimicrobial metabolite from a marine sponge Tetrahedron Letters. 20: 4163-4166. DOI: 10.1016/S0040-4039(01)86533-3  0.353
1979 Howard BM, Fenical W, Arnold EV, Clardy J. Obtusin, a unique bromine-containing polycyclic ketal from the red marine alga Tetrahedron Letters. 20: 2841-2844. DOI: 10.1016/S0040-4039(01)86430-3  0.327
1979 Luibrand RT, Erdman TR, Vollmer JJ, Scheuer PJ, Finer J, Clardy J. Ilimaquinone, a sesquiterpenoid quinone from a marine sponge Tetrahedron. 35: 609-612. DOI: 10.1016/0040-4020(79)87004-0  0.339
1979 IRELAND C, FAULKNER DJ, FINER JS, CLARDY J. ChemInform Abstract: CRISPATONE, A METABOLITE OF THE OPISTHOBRANCH MOLLUSC TRIDACHIA CRISPATA Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197922057  0.511
1978 Ireland C, Faulkner DJ, Solheim BA, Clardy J. Tridachione, a propionate-derived metabolite of the opisthobranch mollusc Tridachiella diomedea Journal of the American Chemical Society. 100: 1002-1003. DOI: 10.1021/Ja00471A074  0.531
1978 Woolard FX, Moore RE, Van Engen D, Clardy J. The structure and absolute configuration of chondrocolactone, A halogenated monoterpene from the red alga chondrococcus hornemanni, and a revised structure for chondrocole a Tetrahedron Letters. 19: 2367-2370. DOI: 10.1016/S0040-4039(01)94776-8  0.306
1978 Bardouille V, Mootoo BS, Hirotsu K, Clardy J. Sesquiterpenes from Pityrogramma calomelanos Phytochemistry. 17: 275-277. DOI: 10.1016/S0031-9422(00)94163-3  0.348
1977 Howard BM, Fenical W, Finer J, Hirotsu K, Clardy J. Neoconcinndiol hydroperoxide, a novel marine diterpenoid from the red alga Laurencia. Journal of the American Chemical Society. 99: 6440-1. PMID 893894 DOI: 10.1021/Ja00461A045  0.325
1977 Prestwich GD, Solheim BA, Clardy J, Pilkiewicz FG, Miura I, Tanis SP, Nakanishi K. Kempene-1 and -2, unusual tetracyclic diterpenes from Nasutitermes termite soldiers Journal of the American Chemical Society. 99: 8082-8083. DOI: 10.1021/Ja00466A068  0.319
1977 Ahmad Y, Fatima K, Rahman A, Occolowitz J, Solheim B, Clardy J, Garnick R, LeQuesne P. Additions and Corrections - Structure and Absolute Configuration of Strictamine and Strictalamine from Rhazya stricta. Stereochemistry of the Picralima Alkaloids. Journal of the American Chemical Society. 99: 3894-3894. DOI: 10.1021/Ja00453A606  0.312
1977 Ahmad Y, Fatima K, Atta-ur-Rahman, Occolowitz JL, Solheim BA, Clardy J, Garnick RL, Quesne PWL. Structure and absolute configuration of strictamine and strictalamine from Rhazya stricta. Stereochemistry of the Picralima alkaloids Journal of the American Chemical Society. 99: 1943-1946. DOI: 10.1021/Ja00448A041  0.34
1977 Greenhouse R, Borden WT, Hirotsu K, Clardy J. Synthesis, trapping, and dimerization of 9,10-benzotricyclo[3.3.2.03,7]deca-3(7),9(10)-diene. X-ray crystal structure of the dimer Journal of the American Chemical Society. 99: 1664-1666. DOI: 10.1021/Ja00447A074  0.305
1977 Springer JP, Bűchi G, Kobbe B, Demain AL, Clardy J. The structure of ditryptophenaline - a new metabolite of Tetrahedron Letters. 18: 2403-2406. DOI: 10.1016/S0040-4039(01)83777-1  0.328
1977 Faulkner D, Ravi B, Finer J, Clardy J. Diterpenes from Dictyota dichotoma Phytochemistry. 16: 991-993. DOI: 10.1016/S0031-9422(00)86707-2  0.317
1976 Macmillan JG, Springer JP, Clardy J, Cole RJ, Kirksey JW. Letter: Structure and synthesis of verruculotoxin, a new mycotoxin from Penicillium verruculosum Peyronel. Journal of the American Chemical Society. 98: 246-7. PMID 1244370 DOI: 10.1021/Ja00417A046  0.332
1976 Ireland C, Faulkner DJ, Finer J, Clardy J. Letter: A novel diterpene from Dollabella californica. Journal of the American Chemical Society. 98: 4664-5. PMID 932371 DOI: 10.1021/Ja00431A063  0.564
1976 Smith CR, Miller RW, Weisleder D, Rohwedder WK, Eickman N, Clardy J. Celorbicol, isocelorbicol, and their esters: new sesquiterpenoids from Celastrus orbiculatus The Journal of Organic Chemistry. 41: 3264-3269. DOI: 10.1021/Jo00882A012  0.348
1976 Springer JP, Clardy J, Wells JM, Cole RJ, Kirksey JW, Macfarlane RD, Torgerson DF. Isolation and structure determination of the mycotoxin chaetoglobosin C, a new [13] cytochalasin Tetrahedron Letters. 17: 1355-1358. DOI: 10.1016/S0040-4039(00)78063-4  0.328
1976 Flamm BL, Pettus JA, Sims JJ, Springer JP, Clardy J. Isolation of epoxydecompostin from gray and its structure revision Tetrahedron Letters. 17: 2671-2674. DOI: 10.1016/S0040-4039(00)77791-4  0.323
1976 Burke BA, Chan WR, Prince EC, Manchand PS, Eickman N, Clardy J. The structure of corylifuran, A clerodane-type diterpene from Croton corylifolius lam Tetrahedron. 32: 1881-1884. DOI: 10.1016/0040-4020(76)85190-3  0.314
1976 Macmillan JG, Springer JP, Clardy J, Cole RJ, Kirksey JW. Structure And Synthesis Of Verruculotoxin, A New Mycotoxin From Penicillium Verruculosum Peyronel Cheminform. 7. DOI: 10.1002/Chin.197613375  0.334
1975 Pezzanite JO, Clardy J, Lau PY, Wood G, Walker DL, Fraser-Reid B. Letter: A revised structure for the antibiotic pillaromycin A. Journal of the American Chemical Society. 97: 6250-1. PMID 1176733 DOI: 10.1021/Ja00854A054  0.306
1975 Cole RJ, Kirksey JW, Cox RH, Clardy J. Structure of the tremor-producing indole, TR-2. Journal of Agricultural and Food Chemistry. 23: 1015-8. PMID 1159175 DOI: 10.1021/Jf60201A017  0.314
1975 Lisy JM, Clardy J, Anchel M, Weinreb SM. X-Ray structure of phlebiakauranol and phlebianorkauranol, highly oxygenated antibacterial metabolites of Phlebia strigosozonata Journal of the Chemical Society, Chemical Communications. 406-407. DOI: 10.1039/C39750000406  0.327
1975 Chan WR, Prince EC, Manchand PS, Springer JP, Clardy J. Structure of crotofolin A, a diterpene with a new skeleton Journal of the American Chemical Society. 97: 4437-4439. DOI: 10.1021/Ja00848A071  0.321
1975 Boeckman R, Fayos J, Clardy J. Additions and Corrections - A Revised Structure of Vermiculine. A novel Macrolide Dilactone Antibiotic from Penicillium vermiculatum. Journal of the American Chemical Society. 97: 1988-1988. DOI: 10.1021/Ja00840A615  0.324
1975 Chan WR, Prince EC, Manchand PS, Springer JP, Clardy J. The Structure Of Crotofolin A, A Diterpene With A New Skeleton Cheminform. 6. DOI: 10.1002/Chin.197541069  0.321
1974 Swenton JS, Hyatt JA, Lisy JM, Clardy J. Photochemical cycloadditions of triplet 1,3-dimethyluracil to olefins. Structural studies on the adducts Journal of the American Chemical Society. 96: 4885-4891. PMID 4853623 DOI: 10.1002/Chin.197440314  0.307
1974 Springer JP, Clardy J, Cole RJ, Kirksey JW, Hill RK, Carlson MR, Isidor JL. Structure and synthesis of moniliformin, a novel cyclobutane microbial toxin. Journal of the American Chemical Society. 96: 2267-8. PMID 4833647 DOI: 10.1002/Chin.197424224  0.345
1974 Fayos J, Lokensgard D, Clardy J, Cole RJ, Kirksey JW. Letter: Structure of verruculogen, a tremor producing peroxide from Penicillium verruculosum. Journal of the American Chemical Society. 96: 6785-7. PMID 4414411 DOI: 10.1021/Ja00828A054  0.303
1974 Boeckman RK, Fayos J, Clardy J. Letter: A revised structure of vermiculine. A novel macrolide dilactone antibiotic from Penicillium vermiculatum. Journal of the American Chemical Society. 96: 5954-6. PMID 4414095 DOI: 10.1021/Ja00825A054  0.327
1974 Fayos J, Lokensgard D, Clardy J, Cole RJ, Kirksey JW. Structure Of Verruculogen, A Tremor Producing Peroxide From Penicillium Verruculosum Cheminform. 5. DOI: 10.1002/Chin.197452472  0.306
1974 Boeckman RKJ, Fayos J, Clardy J. A Revised Structure Of Vermiculine, A Novel Macrolide Dilactone Antibiotic From Penicillium Vermiculatum Cheminform. 5. DOI: 10.1002/Chin.197446457  0.329
1974 KUTNEY JP, COOK G, COOK J, ITOH I, CLARDY J, FAYOS J, BROWN P, SVOBODA GH. ChemInform Abstract: STUDIES ON VINCA ALKALOIDS, THE STRUCTURE OF VINCARODINE Chemischer Informationsdienst. 5. DOI: 10.1002/Chin.197437093  0.313
1973 Wright H, Clardy J, Ferris JP. Structures of the Lythraceae alkaloids lythrumine and acetyllythrumine Journal of the American Chemical Society. 95: 6467-6468. DOI: 10.1021/Ja00800A061  0.307
1973 Kutney JP, Fuji K, Treasurywala AM, Fayos J, Clardy J, Scott AI, Wei CC. Structure and absolute configuration of (+)-coronaridine hydrobromide. Absolute configuration of the Iboga alkaloids Journal of the American Chemical Society. 95: 5407-5409. DOI: 10.1021/Ja00797A049  0.307
1973 WRIGHT H, CLARDY J, FERRIS JP. ChemInform Abstract: LYTHRACEAE ALKALOIDS PART 11, STRUCTURES OF THE LYTHRACEAE ALKALOIDS LYTHRUMINE AND ACETYLLYTHRUMINE Chemischer Informationsdienst. 4. DOI: 10.1002/Chin.197347463  0.319
1973 KUTNEY JP, FUJI K, TREASURYWALA AM, FAYOS J, CLARDY J, SCOTT AI, WEI CC. ChemInform Abstract: STRUCTURE AND ABSOLUTE CONFIGURATION OF (+)-CORONARIDINE HYDROBROMIDE, A COMMENT ON THE ABSOLUTE CONFIGURATION OF THE IBOGA ALKALOIDS Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197343442  0.307
1972 Gougoutas JZ, Clardy JC. Solid-state chemistry of organic polyvalent iodine compounds. I. The crystal structures of two polymorphs of 1-(2′-iodobenzoyloxy)-1,2-benziodoxolin-3-one Journal of Solid State Chemistry. 4: 230-242. DOI: 10.1016/0022-4596(72)90111-9  0.589
1972 Gougoutas JZ, Clardy JC. Solid-state coordination bonding to polyvalent iodine-The structure of 1-acetoxy-1,2-benziodoxolin-3-one Journal of Solid State Chemistry. 4: 226-229. DOI: 10.1016/0022-4596(72)90110-7  0.582
1970 Clardy J, Hauser FM, Dahm D, Jacobson RA, Wildman WC. Molecular structure and absolute configuration of alkaloids related to 5,10-ethanophenanthridine [8] Journal of the American Chemical Society. 92: 6337-6339. DOI: 10.1021/Ja00724A043  0.303
1965 Berry R, Clardy J, Schafer ME. 1, 4 Dehydrobenzene: A stable species Tetrahedron Letters. 6: 1003-1010. DOI: 10.1016/S0040-4039(01)99515-2  0.351
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