Fen-Biao Gao - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Neuroscience Biology

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fang M, Deibler SK, Nana AL, Vatsavayai SC, Banday S, Zhou Y, Almeida S, Weiss A, Brown RH, Seeley WW, Gao FB, Green MR. Loss of TDP-43 function contributes to genomic instability in amyotrophic lateral sclerosis. Frontiers in Neuroscience. 17: 1251228. PMID 37849894 DOI: 10.3389/fnins.2023.1251228  0.308
2023 Rojas F, Aguilar R, Almeida S, Fritz E, Corvalán D, Ampuero E, Abarzúa S, Garcés P, Amaro A, Diaz I, Arredondo C, Cortes N, Sanchez M, Mercado C, Varela-Nallar L, ... Gao FB, et al. Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43 mutation display a mild reactive state and release polyP toxic to motoneurons. Frontiers in Cell and Developmental Biology. 11: 1226604. PMID 37645251 DOI: 10.3389/fcell.2023.1226604  0.303
2023 Lorenzini I, Alsop E, Levy J, Gittings LM, Lall D, Rabichow BE, Moore S, Pevey R, Bustos LM, Burciu C, Bhatia D, Singer M, Saul J, McQuade A, Tzioras M, ... ... Gao FB, et al. Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features. Frontiers in Cellular Neuroscience. 17: 1179796. PMID 37346371 DOI: 10.3389/fncel.2023.1179796  0.387
2023 Lee S, Jun YW, Linares GR, Butler B, Yuva-Adyemir Y, Moore J, Krishnan G, Ruiz-Juarez B, Santana M, Pons M, Silverman N, Weng Z, Ichida JK, Gao FB. Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD. Neuron. PMID 36931278 DOI: 10.1016/j.neuron.2023.02.029  0.355
2023 Jun YW, Lee S, Ban BK, Lee JA, Gao FB. Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis. Autophagy. 1-17. PMID 36849436 DOI: 10.1080/15548627.2023.2169309  0.324
2023 Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C, Macklin-Isquierdo S, Perry S, Duhaime S, Maios C, Chang J, ... ... Gao FB, et al. PIKFYVE inhibition mitigates disease in models of diverse forms of ALS. Cell. PMID 36754049 DOI: 10.1016/j.cell.2023.01.005  0.307
2023 Phillips HL, Dai H, Choi SY, Jansen-West K, Zajicek AS, Daly L, Petrucelli L, Gao FB, Yao WD. Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia. Neuron. PMID 36638803 DOI: 10.1016/j.neuron.2022.12.027  0.69
2022 Chen Y, Krishnan G, Parsi S, Pons M, Nikolaki V, Cao L, Xu Z, Gao FB. The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias. Acta Neuropathologica Communications. 10: 169. PMID 36414997 DOI: 10.1186/s40478-022-01476-8  0.328
2022 Meijboom KE, Abdallah A, Fordham NP, Nagase H, Rodriguez T, Kraus C, Gendron TF, Krishnan G, Esanov R, Andrade NS, Rybin MJ, Ramic M, Stephens ZD, Edraki A, Blackwood MT, ... ... Gao FB, et al. CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro. Nature Communications. 13: 6286. PMID 36271076 DOI: 10.1038/s41467-022-33332-7  0.383
2021 Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, Blum JA, Castruita PA, Linares GR, Ruan K, Ramaswami G, Simon DJ, Nof A, Santana M, Han K, ... ... Gao FB, et al. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. PMID 33482083 DOI: 10.1016/j.cell.2020.12.025  0.326
2020 Lu Y, West RJH, Pons M, Sweeney ST, Gao FB. Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila. Scientific Reports. 10: 14221. PMID 32848189 DOI: 10.1038/S41598-020-71097-5  0.39
2020 Li S, Wu Z, Li Y, Tantray I, De Stefani D, Mattarei A, Krishnan G, Gao FB, Vogel H, Lu B. Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD. Cell Reports. 32: 107989. PMID 32755582 DOI: 10.1016/J.Celrep.2020.107989  0.39
2020 Krishnan G, Zhang Y, Gu Y, Kankel MW, Gao FB, Almeida S. CRISPR deletion of the C9ORF72 promoter in ALS/FTD patient motor neurons abolishes production of dipeptide repeat proteins and rescues neurodegeneration. Acta Neuropathologica. PMID 32266467 DOI: 10.1007/S00401-020-02154-6  0.408
2020 Frew J, Baradaran-Heravi A, Balgi AD, Wu X, Yan TD, Arns S, Shidmoossavee FS, Tan J, Jaquith JB, Jansen-West KR, Lynn FC, Gao FB, Petrucelli L, Feldman HH, Mackenzie IR, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Molecular Neurodegeneration. 15: 21. PMID 32178712 DOI: 10.1186/S13024-020-00369-5  0.342
2019 Yuva-Aydemir Y, Almeida S, Krishnan G, Gendron TF, Gao FB. Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD. Nature Communications. 10: 5466. PMID 31784536 DOI: 10.1038/s41467-019-13477-8  0.402
2019 Almeida S, Krishnan G, Rushe M, Gu Y, Kankel MW, Gao FB. Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells. Acta Neuropathologica. PMID 31624870 DOI: 10.1007/S00401-019-02083-Z  0.343
2019 Cheng W, Wang S, Zhang Z, Morgens DW, Hayes LR, Lee S, Portz B, Xie Y, Nguyen BV, Haney MS, Yan S, Dong D, Coyne AN, Yang J, Xian F, ... ... Gao FB, et al. CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation. Neuron. PMID 31587919 DOI: 10.1016/J.Neuron.2019.09.003  0.403
2019 Choi SY, Lopez-Gonzalez R, Krishnan G, Phillips HL, Li AN, Seeley WW, Yao WD, Almeida S, Gao FB. C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo. Nature Neuroscience. PMID 31086314 DOI: 10.1038/S41593-019-0397-0  0.734
2019 Lopez-Gonzalez R, Yang D, Pribadi M, Kim TS, Krishnan G, Choi SY, Lee S, Coppola G, Gao FB. Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in -ALS/FTD. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019093 DOI: 10.1073/Pnas.1901313116  0.733
2018 Yuva-Aydemir Y, Almeida S, Gao FB. Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC Models. Trends in Neurosciences. PMID 29729808 DOI: 10.1016/J.Tins.2018.04.002  0.473
2018 Liu X, He J, Gao FB, Gitler AD, Fan D. The Epidemiology and Genetics of Amyotrophic Lateral Sclerosis in China. Brain Research. PMID 29501653 DOI: 10.1016/J.Brainres.2018.02.035  0.344
2018 West RJH, Ugbode C, Gao FB, Sweeney ST. The Pro-Apoptotic JNK Scaffold POSH/SH3RF1 Mediates CHMP2BIntron5-Associated Toxicity in Animal Models of Frontotemporal Dementia. Human Molecular Genetics. PMID 29432529 DOI: 10.1093/Hmg/Ddy048  0.475
2018 Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, et al. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 172: 590-604.e13. PMID 29373831 DOI: 10.1016/J.Cell.2017.12.032  0.394
2017 Gao FB, Richter JD, Cleveland DW. Rethinking Unconventional Translation in Neurodegeneration. Cell. 171: 994-1000. PMID 29149615 DOI: 10.1016/J.Cell.2017.10.042  0.347
2017 Gao FB, Almeida S, Lopez-Gonzalez R. Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder. The Embo Journal. PMID 28916614 DOI: 10.15252/Embj.201797568  0.425
2017 Yin S, Lopez-Gonzalez R, Kunz RC, Gangopadhyay J, Borufka C, Gygi SP, Gao FB, Reed R. Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients. Cell Reports. 19: 2244-2256. PMID 28614712 DOI: 10.1016/J.Celrep.2017.05.056  0.387
2017 Wu CH, Giampetruzzi A, Tran H, Fallini C, Gao FB, Landers JE. A Drosophila model of ALS reveals a partial loss of function of causative human PFN1 mutants. Human Molecular Genetics. PMID 28379367 DOI: 10.1093/Hmg/Ddx112  0.428
2017 Gao FB, Richter JD. Microsatellite Expansion Diseases: Repeat Toxicity Found in Translation. Neuron. 93: 249-251. PMID 28103472 DOI: 10.1016/J.Neuron.2017.01.001  0.352
2016 Lopez-Gonzalez R, Lu Y, Gendron TF, Karydas A, Tran H, Yang D, Petrucelli L, Miller BL, Almeida S, Gao FB. Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons. Neuron. PMID 27720481 DOI: 10.1016/J.Neuron.2016.09.015  0.333
2016 Biswas MH, Almeida S, Lopez-Gonzalez R, Mao W, Zhang Z, Karydas A, Geschwind MD, Biernat J, Mandelkow EM, Futai K, Miller BL, Gao FB. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations. Stem Cell Reports. PMID 27594586 DOI: 10.1016/J.Stemcr.2016.08.006  0.386
2016 Silva MC, Cheng C, Mair W, Almeida S, Fong H, Biswas MH, Zhang Z, Huang Y, Temple S, Coppola G, Geschwind DH, Karydas A, Miller BL, Kosik KS, Gao FB, et al. Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability. Stem Cell Reports. PMID 27594585 DOI: 10.1016/J.Stemcr.2016.08.001  0.465
2016 Kramer NJ, Carlomagno Y, Zhang YJ, Almeida S, Cook CN, Gendron TF, Prudencio M, Van Blitterswijk M, Belzil V, Couthouis J, Paul JW, Goodman LD, Daughrity L, Chew J, Garrett A, ... ... Gao FB, et al. Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. Science (New York, N.Y.). 353: 708-12. PMID 27516603 DOI: 10.1126/Science.Aaf7791  0.355
2016 Swartz EW, Baek J, Pribadi M, Wojta KJ, Almeida S, Karydas A, Gao FB, Miller BL, Coppola G. A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes. Stem Cells Translational Medicine. PMID 27369896 DOI: 10.5966/Sctm.2015-0340  0.342
2016 Almeida S, Gao FB. Lost & found: C9ORF72 and the autophagy pathway in ALS/FTD. The Embo Journal. 35: 1251-3. PMID 27154207 DOI: 10.15252/Embj.201694578  0.402
2016 Almeida S, Gao F, Coppola G, Gao FB. Suberoylanilide hydroxamic acid increases progranulin production in iPSC-derived cortical neurons of frontotemporal dementia patients. Neurobiology of Aging. 42: 35-40. PMID 27143419 DOI: 10.1016/J.Neurobiolaging.2016.03.001  0.413
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Gao FB, ... ... Gao F, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.304
2015 Schweizer Burguete A, Almeida S, Gao FB, Kalb R, Akins MR, Bonini NM. GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function. Elife. 4. PMID 26650351 DOI: 10.7554/Elife.08881  0.303
2015 Peters OM, Cabrera GT, Tran H, Gendron TF, McKeon JE, Metterville J, Weiss A, Wightman N, Salameh J, Kim J, Sun H, Boylan KB, Dickson D, Kennedy Z, Lin Z, ... ... Gao FB, et al. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice. Neuron. 88: 902-909. PMID 26637797 DOI: 10.1016/J.Neuron.2015.11.018  0.407
2015 Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport. Nature. 525: 129-33. PMID 26308899 DOI: 10.1038/Nature14974  0.351
2015 Yang D, Abdallah A, Li Z, Lu Y, Almeida S, Gao FB. FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions. Acta Neuropathologica. PMID 26031661 DOI: 10.1007/S00401-015-1448-6  0.508
2015 Yuva-Aydemir Y, Xu XL, Aydemir O, Gascon E, Sayin S, Zhou W, Hong Y, Gao FB. Downregulation of the Host Gene jigr1 by miR-92 Is Essential for Neuroblast Self-Renewal in Drosophila. Plos Genetics. 11: e1005264. PMID 26000445 DOI: 10.1371/Journal.Pgen.1005264  0.301
2014 Gao FB, Taylor JP. RNA metabolism in neurological disease. Brain Research. 1584: 1-2. PMID 25248315 DOI: 10.1016/J.Brainres.2014.09.011  0.438
2014 Gascon E, Gao FB. The emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disorders. Journal of Neurogenetics. 28: 30-40. PMID 24506814 DOI: 10.3109/01677063.2013.876021  0.388
2014 Lee WC, Almeida S, Prudencio M, Caulfield TR, Zhang YJ, Tay WM, Bauer PO, Chew J, Sasaguri H, Jansen-West KR, Gendron TF, Stetler CT, Finch N, Mackenzie IR, Rademakers R, ... Gao FB, et al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Human Molecular Genetics. 23: 1467-78. PMID 24163244 DOI: 10.1093/Hmg/Ddt534  0.301
2014 Cheruiyot A, Lee JA, Gao FB, Ahmad ST. Expression of mutant CHMP2B, an ESCRT-III component involved in frontotemporal dementia, causes eye deformities due to Notch misregulation in Drosophila. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 667-75. PMID 24158394 DOI: 10.1096/Fj.13-234138  0.3
2013 Zhang Z, Almeida S, Lu Y, Nishimura AL, Peng L, Sun D, Wu B, Karydas AM, Tartaglia MC, Fong JC, Miller BL, Farese RV, Moore MJ, Shaw CE, Gao FB. Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations. Plos One. 8: e76055. PMID 24143176 DOI: 10.1371/Journal.Pone.0076055  0.478
2013 Lu Y, Zhang Z, Sun D, Sweeney ST, Gao FB. Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation. Molecular Cell. 52: 264-71. PMID 24095276 DOI: 10.1016/J.Molcel.2013.08.041  0.38
2013 Almeida S, Gascon E, Tran H, Chou HJ, Gendron TF, Degroot S, Tapper AR, Sellier C, Charlet-Berguerand N, Karydas A, Seeley WW, Boxer AL, Petrucelli L, Miller BL, Gao FB. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. Acta Neuropathologica. 126: 385-99. PMID 23836290 DOI: 10.1007/S00401-013-1149-Y  0.38
2013 Filiano AJ, Martens LH, Young AH, Warmus BA, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang EJ, Gao FB, Farese RV, Roberson ED. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5352-61. PMID 23516300 DOI: 10.1523/Jneurosci.6103-11.2013  0.413
2013 Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 176-88. PMID 23043900 DOI: 10.1016/J.Jalz.2012.03.002  0.312
2013 Li Z, Lu Y, Xu XL, Gao FB. The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila. Human Molecular Genetics. 22: 218-25. PMID 23042786 DOI: 10.1093/Hmg/Dds420  0.481
2012 Almeida S, Zhang Z, Coppola G, Mao W, Futai K, Karydas A, Geschwind MD, Tartaglia MC, Gao F, Gianni D, Sena-Esteves M, Geschwind DH, Miller BL, Farese RV, Gao FB. Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects. Cell Reports. 2: 789-98. PMID 23063362 DOI: 10.1016/J.Celrep.2012.09.007  0.444
2012 Almeida S, Delaloy C, Liu L, Gao FB. Protocols for investigating microRNA functions in human neural progenitor cells. Methods in Molecular Biology (Clifton, N.J.). 916: 387-402. PMID 22914955 DOI: 10.1007/978-1-61779-980-8_28  0.322
2012 González-Pérez P, Lu Y, Chian RJ, Sapp PC, Tanzi RE, Bertram L, McKenna-Yasek D, Gao FB, Brown RH. Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS. Neurobiology of Disease. 48: 391-8. PMID 22766032 DOI: 10.1016/J.Nbd.2012.06.018  0.333
2012 Gascon E, Gao FB. Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration. Frontiers in Neuroscience. 6: 48. PMID 22509148 DOI: 10.3389/Fnins.2012.00048  0.321
2012 Lee JA, Gao FB. Neuronal Functions of ESCRTs. Experimental Neurobiology. 21: 9-15. PMID 22438674 DOI: 10.5607/En.2012.21.1.9  0.447
2012 Sun K, Westholm JO, Tsurudome K, Hagen JW, Lu Y, Kohwi M, Betel D, Gao FB, Haghighi AP, Doe CQ, Lai EC. Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants. Plos Genetics. 8: e1002515. PMID 22347817 DOI: 10.1371/Journal.Pgen.1002515  0.323
2012 Filiano A, Martens LH, Young A, Warmus B, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang E, Gao F, Farese R, Roberson E. O1-05-03: Neuronal effects of progranulin deficiency contribute to frontotemporal dementia independent of neuroinflammation Alzheimer's & Dementia. 8: P93-P93. DOI: 10.1016/J.Jalz.2012.05.228  0.368
2011 Almeida S, Zhou L, Gao FB. Progranulin, a glycoprotein deficient in frontotemporal dementia, is a novel substrate of several protein disulfide isomerase family proteins. Plos One. 6: e26454. PMID 22028881 DOI: 10.1371/Journal.Pone.0026454  0.338
2011 Lee JA, Liu L, Javier R, Kreitzer AC, Delaloy C, Gao FB. ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons. Molecular Brain. 4: 37. PMID 21975012 DOI: 10.1186/1756-6606-4-37  0.422
2011 Xu XL, Zong R, Li Z, Biswas MH, Fang Z, Nelson DL, Gao FB. FXR1P but not FMRP regulates the levels of mammalian brain-specific microRNA-9 and microRNA-124. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13705-9. PMID 21957233 DOI: 10.1523/Jneurosci.2827-11.2011  0.306
2011 Yuva-Aydemir Y, Simkin A, Gascon E, Gao FB. MicroRNA-9: functional evolution of a conserved small regulatory RNA. Rna Biology. 8: 557-64. PMID 21697652 DOI: 10.4161/Rna.8.4.16019  0.337
2010 Gao FB. Context-dependent functions of specific microRNAs in neuronal development. Neural Development. 5: 25. PMID 20920300 DOI: 10.1186/1749-8104-5-25  0.39
2010 Delaloy C, Gao FB. A new role for microRNA-9 in human neural progenitor cells. Cell Cycle (Georgetown, Tex.). 9: 2913-4. PMID 20676037 DOI: 10.4161/Cc.9.15.12699  0.427
2010 Jiao J, Herl LD, Farese RV, Gao FB. MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia. Plos One. 5: e10551. PMID 20479936 DOI: 10.1371/Journal.Pone.0010551  0.304
2010 Delaloy C, Liu L, Lee JA, Su H, Shen F, Yang GY, Young WL, Ivey KN, Gao FB. MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell. 6: 323-35. PMID 20362537 DOI: 10.1016/J.Stem.2010.02.015  0.309
2009 Lu Y, Ferris J, Gao FB. Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching. Molecular Brain. 2: 30. PMID 19781077 DOI: 10.1186/1756-6606-2-30  0.467
2009 Lee JA, Liu L, Gao FB. Autophagy defects contribute to neurodegeneration induced by dysfunctional ESCRT-III. Autophagy. 5: 1070-2. PMID 19738424 DOI: 10.4161/Auto.5.7.9823  0.472
2009 Ahmad ST, Sweeney ST, Lee JA, Sweeney NT, Gao FB. Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. 106: 12168-73. PMID 19581577 DOI: 10.1073/Pnas.0903134106  0.365
2009 Lee JA, Gao FB. Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8506-11. PMID 19571141 DOI: 10.1523/Jneurosci.0924-09.2009  0.48
2009 Lu Y, Wang F, Li Y, Ferris J, Lee JA, Gao FB. The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches. Human Molecular Genetics. 18: 454-62. PMID 18996915 DOI: 10.1093/Hmg/Ddn373  0.387
2008 Lee JA, Gao FB. ESCRT, autophagy, and frontotemporal dementia. Bmb Reports. 41: 827-32. PMID 19123971 DOI: 10.5483/Bmbrep.2008.41.12.827  0.438
2008 Xu XL, Li Y, Wang F, Gao FB. The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11883-9. PMID 19005053 DOI: 10.1523/Jneurosci.4114-08.2008  0.338
2008 Lee JA, Gao FB. Regulation of Abeta pathology by beclin 1: a protective role for autophagy? The Journal of Clinical Investigation. 118: 2015-8. PMID 18497881 DOI: 10.1172/Jci35662  0.308
2008 Lee JA, Gao FB. Roles of ESCRT in autophagy-associated neurodegeneration. Autophagy. 4: 230-2. PMID 18094607 DOI: 10.4161/Auto.5384  0.429
2008 Gao FB. Posttranscriptional control of neuronal development by microRNA networks. Trends in Neurosciences. 31: 20-6. PMID 18054394 DOI: 10.1016/J.Tins.2007.10.004  0.361
2007 Gao FB. Molecular and cellular mechanisms of dendritic morphogenesis Current Opinion in Neurobiology. 17: 525-532. PMID 17933513 DOI: 10.1016/J.Conb.2007.08.004  0.397
2007 Lee JA, Beigneux A, Ahmad ST, Young SG, Gao FB. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Current Biology : Cb. 17: 1561-7. PMID 17683935 DOI: 10.1016/J.Cub.2007.07.029  0.502
2006 Li Y, Wang F, Lee JA, Gao FB. MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila. Genes & Development. 20: 2793-805. PMID 17015424 DOI: 10.1101/Gad.1466306  0.307
2006 Tassetto M, Gao FB. Transcriptional control of dendritic patterning in Drosophila neurons. Genome Biology. 7: 225. PMID 16879736 DOI: 10.1186/Gb-2006-7-7-225  0.4
2006 Sweeney NT, Brenman JE, Jan YN, Gao FB. The coiled-coil protein shrub controls neuronal morphogenesis in Drosophila. Current Biology : Cb. 16: 1006-11. PMID 16713958 DOI: 10.1016/J.Cub.2006.03.067  0.353
2005 Li W, Li Y, Gao FB. Abelson, enabled, and p120 catenin exert distinct effects on dendritic morphogenesis in Drosophila. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 512-22. PMID 16003769 DOI: 10.1002/Dvdy.20496  0.397
2004 Li W, Wang F, Menut L, Gao FB. BTB/POZ-zinc finger protein abrupt suppresses dendritic branching in a neuronal subtype-specific and dosage-dependent manner. Neuron. 43: 823-34. PMID 15363393 DOI: 10.1016/J.Neuron.2004.08.040  0.439
2004 Xu K, Bogert BA, Li W, Su K, Lee A, Gao FB. The fragile X-related gene affects the crawling behavior of Drosophila larvae by regulating the mRNA level of the DEG/ENaC protein pickpocket1. Current Biology : Cb. 14: 1025-34. PMID 15202995 DOI: 10.1016/J.Cub.2004.05.055  0.336
2003 Lee A, Li W, Xu K, Bogert BA, Su K, Gao FB. Control of dendritic development by the Drosophila fragile X-related gene involves the small GTPase Rac1. Development (Cambridge, England). 130: 5543-52. PMID 14530299 DOI: 10.1242/Dev.00792  0.426
2003 Li W, Gao FB. Actin filament-stabilizing protein tropomyosin regulates the size of dendritic fields. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6171-5. PMID 12867499 DOI: 10.1523/Jneurosci.23-15-06171.2003  0.384
2003 Gao FB, Bogert BA. Genetic control of dendritic morphogenesis in Drosophila. Trends in Neurosciences. 26: 262-8. PMID 12744843 DOI: 10.1016/S0166-2236(03)00078-X  0.386
2002 Gao FB. Understanding fragile X syndrome: Insights from retarded flies Neuron. 34: 859-862. PMID 12086633 DOI: 10.1016/S0896-6273(02)00740-7  0.336
2002 Sweeney NT, Li W, Gao FB. Genetic manipulation of single neurons in vivo reveals specific roles of flamingo in neuronal morphogenesis. Developmental Biology. 247: 76-88. PMID 12074553 DOI: 10.1006/Dbio.2002.0702  0.418
1998 Raff MC, Durand B, Gao FB. Cell number control and timing in animal development: the oligodendrocyte cell lineage. The International Journal of Developmental Biology. 42: 263-7. PMID 9654007 DOI: 10.1387/Ijdb.9654007  0.3
1998 Gao FB. Messenger RNAs in dendrites: Localization, stability, and implications for neuronal function Bioessays. 20: 70-78. PMID 9504049 DOI: 10.1002/(Sici)1521-1878(199801)20:1<70::Aid-Bies10>3.0.Co;2-5  0.409
1997 Durand B, Gao FB, Raff M. Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation Embo Journal. 16: 306-317. PMID 9029151 DOI: 10.1093/Emboj/16.2.306  0.313
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