| Year |
Citation |
Score |
| 2022 |
Artham S, Chang CY, McDonnell DP. Eosinophilia in cancer and its regulation by sex hormones. Trends in Endocrinology and Metabolism: Tem. 34: 5-20. PMID 36443206 DOI: 10.1016/j.tem.2022.11.002 |
0.346 |
|
| 2022 |
Tsuji J, Li T, Grinshpun A, Coorens T, Russo D, Anderson L, Rees R, Nardone A, Patterson C, Lennon NJ, Cibulskis C, Leshchiner I, Tayob N, Tolaney SM, Tung N, ... McDonnell DP, et al. Clinical Efficacy and Whole Exome Sequencing of Liquid Biopsies in a Phase IB/II study of Bazedoxifene and Palbociclib in Hormone Receptor-Positive Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36215125 DOI: 10.1158/1078-0432.CCR-22-2305 |
0.521 |
|
| 2022 |
Sammeta VR, Norris JD, Artham S, Torrice CD, Byemerwa J, Joiner C, Fanning SW, McDonnell DP, Willson TM. A New Chemotype of Chemically Tractable Nonsteroidal Estrogens Based on a Thieno[2,3-]pyrimidine Core. Acs Medicinal Chemistry Letters. 13: 1151-1158. PMID 35859859 DOI: 10.1021/acsmedchemlett.2c00180 |
0.404 |
|
| 2022 |
Chakraborty B, Byemerwa J, Krebs T, Lim F, Chang CY, McDonnell DP. Estrogen receptor signaling in the immune system. Endocrine Reviews. PMID 35709009 DOI: 10.1210/endrev/bnac017 |
0.314 |
|
| 2021 |
Haines CN, Wardell SE, McDonnell DP. Current and emerging estrogen receptor-targeted therapies for the treatment of breast cancer. Essays in Biochemistry. PMID 34328178 DOI: 10.1042/EBC20200174 |
0.422 |
|
| 2020 |
Andreano KJ, Baker JG, Park S, Safi R, Artham S, Oesterreich S, Jeselsohn R, Brown M, Sammons S, Wardell SE, Chang CY, Norris JD, McDonnell DP. The dysregulated pharmacology of clinically relevant ESR1 mutants is normalized by ligand-activated WT receptor. Molecular Cancer Therapeutics. PMID 32381587 DOI: 10.1158/1535-7163.Mct-19-1148 |
0.518 |
|
| 2020 |
Chakraborty B, Bymerwa J, Baldi R, Liu W, Chang C, McDonnell D. Abstract A44: Pharmacologic targeting of estrogen receptor in melanoma to enhance antitumor immunity Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm19-A44 |
0.356 |
|
| 2019 |
Cocce KJ, Jasper JS, Desautels TK, Everett L, Wardell S, Westerling T, Baldi R, Wright TM, Tavares K, Yllanes A, Bae Y, Blitzer JT, Logsdon C, Rakiec DP, Ruddy DA, ... ... McDonnell DP, et al. The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer. Cell Reports. 29: 889-903.e10. PMID 31644911 DOI: 10.1016/J.Celrep.2019.09.032 |
0.4 |
|
| 2019 |
Wardell SE, Yllanes AP, Chao CA, Bae Y, Andreano KJ, Desautels TK, Heetderks KA, Blitzer JT, Norris JD, McDonnell DP. Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy. Breast Cancer Research and Treatment. PMID 31562570 DOI: 10.1007/S10549-019-05454-Y |
0.461 |
|
| 2019 |
Park S, Safi R, Liu X, Baldi R, Liu W, Liu J, Locasale JW, Chang CY, McDonnell DP. Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer. Cell Reports. 27: 3587-3601.e4. PMID 31216477 DOI: 10.1016/J.Celrep.2019.05.066 |
0.363 |
|
| 2019 |
Racioppi L, Nelson ER, Huang W, Mukherjee D, Lawrence SA, Lento W, Masci AM, Jiao Y, Park S, York B, Liu Y, Baek AE, Drewry DH, Zuercher WJ, Bertani FR, ... ... McDonnell DP, et al. CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer. Nature Communications. 10: 2450. PMID 31164648 DOI: 10.1038/S41467-019-10424-5 |
0.318 |
|
| 2019 |
Gaillard SL, Andreano KJ, Gay LM, Steiner M, Jorgensen MS, Davidson BA, Havrilesky LJ, Alvarez Secord A, Valea FA, Colon-Otero G, Zajchowski DA, Chang CY, McDonnell DP, Berchuck A, Elvin JA. Constitutively active ESR1 mutations in gynecologic malignancies and clinical response to estrogen-receptor directed therapies. Gynecologic Oncology. PMID 30987772 DOI: 10.1016/J.Ygyno.2019.04.010 |
0.432 |
|
| 2019 |
Wardell SE, Norris JD, McDonnell DP. Targeting mutant estrogen receptors. Elife. 8. PMID 30648967 DOI: 10.7554/Elife.44181 |
0.492 |
|
| 2019 |
McDonnell DP. The Molecular Pharmacology of SERMs. Trends in Endocrinology and Metabolism: Tem. 10: 301-311. PMID 10481160 DOI: 10.1016/S1043-2760(99)00177-0 |
0.503 |
|
| 2019 |
McDonnell DP, Safi R. 1H. Liver X receptor-like receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f89/2019.4 |
0.383 |
|
| 2019 |
Sammons S, Anderson G, Wardell S, McDonnell DP, Marcom PK, Wood K. Combination mTORC1/2 and BCL- XL inhibition in endocrine and CDK4/6-resistant estrogen receptor-positive breast cancer. Journal of Clinical Oncology. 37: e14653-e14653. DOI: 10.1200/Jco.2019.37.15_Suppl.E14653 |
0.371 |
|
| 2018 |
Johng D, Torga G, Ewing CM, Jin K, Norris JD, McDonnell DP, Isaacs WB. HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancer. The Prostate. PMID 30560549 DOI: 10.1002/Pros.23747 |
0.32 |
|
| 2018 |
Salami J, Alabi S, Willard RR, Vitale NJ, Wang J, Dong H, Jin M, McDonnell DP, Crew AP, Neklesa TK, Crews CM. Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance. Communications Biology. 1: 100. PMID 30271980 DOI: 10.1038/s42003-018-0105-8 |
0.338 |
|
| 2018 |
Singh BK, Sinha RA, Tripathi M, Mendoza A, Ohba K, Sy JAC, Xie SY, Zhou J, Ho JP, Chang CY, Wu Y, Giguère V, Bay BH, Vanacker JM, Ghosh S, ... ... McDonnell DP, et al. Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function. Science Signaling. 11. PMID 29945885 DOI: 10.1126/Scisignal.Aam5855 |
0.374 |
|
| 2018 |
Tria GS, Abrams T, Baird J, Burks HE, Firestone B, Gaither LA, Hamann LG, He G, Kirby CA, Kim S, Lombardo F, Macchi KJ, McDonnell DP, Mishina Y, Norris JD, et al. Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. Journal of Medicinal Chemistry. PMID 29562737 DOI: 10.1021/Acs.Jmedchem.7B01682 |
0.502 |
|
| 2018 |
McDonnell DP, Norris JD, Chang CY. Neomorphic ERα Mutations Drive Progression in Breast Cancer and Present a Challenge for New Drug Discovery. Cancer Cell. 33: 153-155. PMID 29438688 DOI: 10.1016/J.Ccell.2018.01.014 |
0.404 |
|
| 2018 |
Gaillard S, Gay LM, Steiner M, Andreano K, Davidson BA, Havrilesky LJ, Secord AA, Valea FA, Colon-Otero G, Zajchowski DA, Chang C, McDonnell DP, Berchuck A, Elvin JA. Assessment of activating estrogen receptor 1 (ESR1) mutations in gynecologic malignancies. Journal of Clinical Oncology. 36: 5590-5590. DOI: 10.1200/Jco.2018.36.15_Suppl.5590 |
0.401 |
|
| 2018 |
Liberti MV, Dai Z, Wardell SE, Baccile JA, Liu X, Gao X, Baldi R, Mehrmohamadi M, Johnson MO, Madhukar NS, Shestov A, Chio IIC, Elemento O, Rathmell JC, Schroeder FC, ... McDonnell DP, et al. Abstract 5496: A predictive model for selective targeting of the Warburg effect through GAPDH inhibition with a natural product Cancer Research. 78: 5496-5496. DOI: 10.1158/1538-7445.Am2018-5496 |
0.342 |
|
| 2018 |
Yao Z, Wardell S, Spasojevic I, Norris J, Katzenellenbogen J, McDonnell D, Josan JS. Abstract 1805: Development of a selective androgen receptor degrader (SARD) for treatment of castration-resistant prostate cancer Cancer Research. 78: 1805-1805. DOI: 10.1158/1538-7445.Am2018-1805 |
0.438 |
|
| 2017 |
McLeod AB, Stice JP, Wardell SE, Alley HM, Chang CY, McDonnell DP. Validation of histone deacetylase 3 as a therapeutic target in castration-resistant prostate cancer. The Prostate. PMID 29243324 DOI: 10.1002/Pros.23467 |
0.361 |
|
| 2017 |
Baek AE, Yu YA, He S, Wardell SE, Chang CY, Kwon S, Pillai RV, McDowell HB, Thompson JW, Dubois LG, Sullivan PM, Kemper JK, Gunn MD, McDonnell DP, Nelson ER. The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells. Nature Communications. 8: 864. PMID 29021522 DOI: 10.1038/S41467-017-00910-Z |
0.332 |
|
| 2017 |
Coons LA, Hewitt SC, Burkholder AB, McDonnell DP, Korach KS. DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin. Endocrinology. 158: 3212-3234. PMID 28977594 DOI: 10.1210/En.2017-00468 |
0.386 |
|
| 2017 |
Liberti MV, Dai Z, Wardell SE, Baccile JA, Liu X, Gao X, Baldi R, Mehrmohamadi M, Johnson MO, Madhukar NS, Shestov AA, Chio IIC, Elemento O, Rathmell JC, Schroeder FC, ... McDonnell DP, et al. A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product. Cell Metabolism. PMID 28918937 DOI: 10.1016/J.Cmet.2017.08.017 |
0.319 |
|
| 2017 |
Norris JD, Ellison SJ, Baker JG, Stagg DB, Wardell SE, Park S, Alley HM, Baldi RM, Yllanes A, Andreano KJ, Stice JP, Lawrence SA, Eisner JR, Price DK, Moore WR, ... ... McDonnell DP, et al. Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer. The Journal of Clinical Investigation. PMID 28463227 DOI: 10.1172/Jci87328 |
0.398 |
|
| 2017 |
Kimbung S, Chang C, Bendahl PO, Dubois L, Thompson WJ, McDonnell DP, Borgquist S. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Endocrine-Related Cancer. PMID 28442559 DOI: 10.1530/Erc-16-0533 |
0.388 |
|
| 2017 |
Burks HE, Abrams T, Kirby CA, Baird J, Fekete A, Hamann LG, Kim S, Lombardo F, Loo A, Lubicka D, Macchi K, McDonnell DP, Mishina Y, Norris JD, Nunez J, et al. Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer. Journal of Medicinal Chemistry. PMID 28296398 DOI: 10.1021/Acs.Jmedchem.6B01468 |
0.482 |
|
| 2017 |
Stice JP, Wardell SE, Norris JD, Yllanes AP, Alley HM, Haney VO, White HS, Safi R, Winter PS, Cocce KJ, Kishton RJ, Lawrence SA, Strum JC, McDonnell DP. CDK4/6 Therapeutic Intervention and Viable Alternative to Taxanes in CRPC. Molecular Cancer Research : McR. PMID 28209757 DOI: 10.1158/1541-7786.Mcr-17-0028 |
0.38 |
|
| 2017 |
Christenson JL, Butterfield KT, Spoelstra NS, Norris JD, Josan JS, Pollock JA, McDonnell DP, Katzenellenbogen BS, Katzenellenbogen JA, Richer JK. MMTV-PyMT and Derived Met-1 Mouse Mammary Tumor Cells as Models for Studying the Role of the Androgen Receptor in Triple-Negative Breast Cancer Progression. Hormones & Cancer. PMID 28194662 DOI: 10.1007/S12672-017-0285-6 |
0.433 |
|
| 2017 |
Alfaqih MA, Nelson ER, Liu W, Safi R, Jasper JS, Macias E, Geradts J, Dubois LG, Thompson W, Freeman MR, Chang CY, Chi JT, McDonnell DP, Freedland SJ. CYP27A1 loss dysregulates cholesterol homeostasis in prostate cancer. Cancer Research. PMID 28130224 DOI: 10.1158/0008-5472.Can-16-2738 |
0.359 |
|
| 2017 |
McDonnell D, Cocce K, Wardell S, Norris J. Abstract IA30: Targeting hormone receptors for degradation: Nuclear receptor downregulation as a therapeutic approach in cancer Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-Ia30 |
0.524 |
|
| 2017 |
Quayle L, Park S, McDonnell D, Ottewell P, Holen I. Abstract P3-07-14: Targeting ERR-α regulated lactate metabolism eliminates drug-resistant breast cancer cells Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P3-07-14 |
0.35 |
|
| 2017 |
Wardell SE, Yllanes AP, Norris JD, Stice JP, White H, Fleming RA, Strum JC, Moore WR, McDonnell DP. Abstract 1588: Effects of the selective CYP17-lyase and androgen receptor (AR) inhibitor, seviteronel, and the cyclin-dependent kinase (CDK) 4/6 inhibitor, G1T38, on tumor growth in an AR-V7+ castration-resistant prostate cancer (CRPC) xenograft model Cancer Research. 77: 1588-1588. DOI: 10.1158/1538-7445.Am2017-1588 |
0.371 |
|
| 2017 |
Kimbung S, Chang C, Bendahl P, Dubois L, Thompson W, McDonnell D, Borgquist S. Impact of the sterol 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol on tumor-pathological features, prognosis and response to statin treatment in breast cancer Annals of Oncology. 28: i4. DOI: 10.1093/Annonc/Mdx142.002 |
0.305 |
|
| 2016 |
Anderson GR, Wardell SE, Cakir M, Crawford L, Leeds JC, Nussbaum DP, Shankar PS, Soderquist RS, Stein EM, Tingley JP, Winter PS, Zieser-Misenheimer EK, Alley HM, Yllanes A, Haney V, ... ... McDonnell DP, et al. PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation. Science Translational Medicine. 8: 369ra175. PMID 27974663 DOI: 10.1126/Scitranslmed.Aae0348 |
0.351 |
|
| 2016 |
Alexander PB, Chen R, Gong C, Yuan L, Jasper JS, Ding Y, Markowitz GJ, Yang P, Xu X, McDonnell DP, Song E, Wang XF. Distinct receptor tyrosine kinase subsets mediate anti-HER2 drug resistance in breast cancer. The Journal of Biological Chemistry. PMID 27903634 DOI: 10.1074/Jbc.M116.754960 |
0.431 |
|
| 2016 |
Pollock JA, Wardell SE, Parent AA, Stagg DB, Ellison SJ, Alley HM, Chao CA, Lawrence SA, Stice JP, Spasojevic I, Baker JG, Kim SH, McDonnell DP, Katzenellenbogen JA, Norris JD. Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer. Nature Chemical Biology. PMID 27501397 DOI: 10.1038/Nchembio.2131 |
0.467 |
|
| 2016 |
Park S, Chang CY, Safi R, Liu X, Baldi R, Jasper JS, Anderson GR, Liu T, Rathmell JC, Dewhirst MW, Wood KC, Locasale JW, McDonnell DP. ERRα Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer. Cell Reports. PMID 27050525 DOI: 10.1016/J.Celrep.2016.03.026 |
0.439 |
|
| 2016 |
Xu X, Zhang Y, Jasper J, Lykken E, Alexander PB, Markowitz GJ, McDonnell DP, Li QJ, Wang XF. MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer. Oncotarget. PMID 26967387 DOI: 10.18632/Oncotarget.7953 |
0.307 |
|
| 2016 |
Ellison S, Norris J, Wardell S, Eisner J, Hoekstra W, Stagg D, Alley H, Moore W, McDonnell D. Abstract P3-14-04: Effects of the dual selective CYP17 lyase inhibitor and androgen receptor (AR) antagonist, VT-464, on AR+ and ER+ tumor models in vitro and in vivo Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-14-04 |
0.445 |
|
| 2016 |
Stice JP, White HS, Wardell SE, Yllanes AY, Lawrence SA, Alley H, McDonnell DP, Strum JC. Abstract 2820: Effects of a CDK 4/6 inhibitor, G1T38, in androgen receptor sensitive and resistant models of castrate resistant prostate cancer Cancer Research. 76: 2820-2820. DOI: 10.1158/1538-7445.Am2016-2820 |
0.371 |
|
| 2015 |
Blessing AM, Ganesan S, Rajapakshe K, Ying Sung Y, Reddy Bollu L, Shi Y, Cheung E, Coarfa C, Chang JT, McDonnell DP, Frigo DE. Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus. Molecular Endocrinology (Baltimore, Md.). 29: 1426-39. PMID 26305679 DOI: 10.1210/Me.2015-1079 |
0.499 |
|
| 2015 |
Wardell SE, Nelson ER, Chao CA, Alley HM, McDonnell DP. Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader. Endocrine-Related Cancer. 22: 713-24. PMID 26162914 DOI: 10.1530/Erc-15-0287 |
0.452 |
|
| 2015 |
Gustafson JL, Neklesa TK, Cox CS, Roth AG, Buckley DL, Tae HS, Sundberg TB, Stagg DB, Hines J, McDonnell DP, Norris JD, Crews CM. Small-Molecule-Mediated Degradation of the Androgen Receptor Through Hydrophobic Tagging. Angewandte Chemie (International Ed. in English). PMID 26083457 DOI: 10.1002/Anie.201503720 |
0.448 |
|
| 2015 |
Lontay B, Bodoor K, Sipos A, Weitzel DH, Loiselle D, Safi R, Zheng D, Devente J, Hickner RC, McDonnell DP, Ribar T, Haystead TA. Pregnancy and Smoothelin-like Protein 1 (SMTNL1) Deletion Promote the Switching of Skeletal Muscle to a Glycolytic Phenotype in Human and Mice. The Journal of Biological Chemistry. 290: 17985-98. PMID 26048986 DOI: 10.1074/Jbc.M115.658120 |
0.313 |
|
| 2015 |
McDonnell DP, Wardell SE, Norris JD. Oral Selective Estrogen Receptor Downregulators (SERDs), a Breakthrough Endocrine Therapy for Breast Cancer. Journal of Medicinal Chemistry. 58: 4883-7. PMID 26039356 DOI: 10.1021/Acs.Jmedchem.5B00760 |
0.469 |
|
| 2015 |
Wardell SE, Ellis MJ, Alley HM, Eisele K, VanArsdale T, Dann SG, Arndt KT, Primeau T, Griffin E, Shao J, Crowder RJ, Lai JP, Norris JD, McDonnell DP, Li S. Efficacy of SERD/SERM Hybrid-CDK4/6 inhibitor combinations in models of endocrine therapy resistant breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 25991817 DOI: 10.1158/1078-0432.Ccr-15-0360 |
0.465 |
|
| 2015 |
Allensworth JL, Evans MK, Bertucci F, Aldrich AJ, Festa RA, Finetti P, Ueno NT, Safi R, McDonnell DP, Thiele DJ, Van Laere S, Devi GR. Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer. Molecular Oncology. 9: 1155-68. PMID 25769405 DOI: 10.1016/J.Molonc.2015.02.007 |
0.317 |
|
| 2015 |
Choudhary M, Kazmin D, Hu P, Thomas RS, McDonnell DP, Malek G. Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways. The Journal of Pathology. 235: 101-12. PMID 25186463 DOI: 10.1002/Path.4433 |
0.363 |
|
| 2015 |
Moore WR, Norris JD, Wardell S, Eisner JR, Hoekstra WJ, Schotzinger RJ, McDonnell DP. Direct effects of the selective CYP17 lyase (L) inhibitor, VT-464, on the androgen receptor (AR) and its oral activity in an F876L tumor mouse xenograft model. Journal of Clinical Oncology. 33: 263-263. DOI: 10.1200/Jco.2015.33.7_Suppl.263 |
0.345 |
|
| 2015 |
Nelson ER, Wardell SE, McDonnell DP. Abstract A82: The cholesterol metabolite, 27-hydroxycholesterol, promotes breast cancer metastasis Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-A82 |
0.397 |
|
| 2015 |
Alfaqih MA, Nelson ER, Safi R, Jasper J, McDonnell DP, Freedland SJ. Abstract PR11: Dysregulation of cholesterol homeostasis through loss of CYP27A1 in prostate cancer; Implications for early detection and prevention of over-treatment Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-Pr11 |
0.336 |
|
| 2015 |
Alwarawrah Y, Hughes P, Safi R, McDonnell DP, Spector NL, Haystead TA. Abstract 2703: Overcoming Lapatinib resistance by the fatty acid synthase inhibitor HS-106 Cancer Research. 75: 2703-2703. DOI: 10.1158/1538-7445.Am2015-2703 |
0.379 |
|
| 2014 |
Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, Anderson GR, Winter PS, Wang T, Alley HM, Kwong LN, Cooper ZA, Tetzlaff M, Chen PL, Rathmell JC, ... ... McDonnell DP, et al. Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Science Signaling. 7: ra121. PMID 25538079 DOI: 10.1126/Scisignal.Aaa1877 |
0.368 |
|
| 2014 |
Nelson ER, Chang CY, McDonnell DP. Cholesterol and breast cancer pathophysiology. Trends in Endocrinology and Metabolism: Tem. 25: 649-55. PMID 25458418 DOI: 10.1016/J.Tem.2014.10.001 |
0.43 |
|
| 2014 |
Safi R, Nelson ER, Chitneni SK, Franz KJ, George DJ, Zalutsky MR, McDonnell DP. Copper signaling axis as a target for prostate cancer therapeutics. Cancer Research. 74: 5819-31. PMID 25320179 DOI: 10.1158/0008-5472.Can-13-3527 |
0.325 |
|
| 2014 |
McDonnell DP, Chang CY, Nelson ER. The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer. Climacteric : the Journal of the International Menopause Society. 17: 60-5. PMID 25320023 DOI: 10.3109/13697137.2014.966949 |
0.381 |
|
| 2014 |
Wright TM, Wardell SE, Jasper JS, Stice JP, Safi R, Nelson ER, McDonnell DP. Delineation of a FOXA1/ERα/AGR2 regulatory loop that is dysregulated in endocrine therapy-resistant breast cancer. Molecular Cancer Research : McR. 12: 1829-39. PMID 25100862 DOI: 10.1158/1541-7786.Mcr-14-0195 |
0.435 |
|
| 2014 |
Gustafsson JA, Katzenellenbogen B, Jameson JL, Roth J, Melmed S, McDonnell D, Wartofsky L, Crowley WF, Griz LH, Becker C, Moore DD, Drucker D, Singh N, O'Malley B. Endocrine Society 2014 Laureate Awards. Hormones & Cancer. 5: 339-55. PMID 25091407 DOI: 10.1007/S12672-014-0193-Y |
0.369 |
|
| 2014 |
Wardell SE, Nelson ER, McDonnell DP. From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs). Steroids. 90: 30-8. PMID 25084324 DOI: 10.1016/J.Steroids.2014.07.013 |
0.545 |
|
| 2014 |
McDonnell DP, Park S, Goulet MT, Jasper J, Wardell SE, Chang CY, Norris JD, Guyton JR, Nelson ER. Obesity, cholesterol metabolism, and breast cancer pathogenesis. Cancer Research. 74: 4976-82. PMID 25060521 DOI: 10.1158/0008-5472.Can-14-1756 |
0.384 |
|
| 2014 |
Yang J, Fuller PJ, Morgan J, Shibata H, McDonnell DP, Clyne CD, Young MJ. Use of phage display to identify novel mineralocorticoid receptor-interacting proteins. Molecular Endocrinology (Baltimore, Md.). 28: 1571-84. PMID 25000480 DOI: 10.1210/Me.2014-1101 |
0.35 |
|
| 2014 |
Scholtz EL, Krishnan S, Ball BA, Corbin CJ, Moeller BC, Stanley SD, McDowell KJ, Hughes AL, McDonnell DP, Conley AJ. Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesterone. Proceedings of the National Academy of Sciences of the United States of America. 111: 3365-70. PMID 24550466 DOI: 10.1073/Pnas.1318163111 |
0.361 |
|
| 2014 |
Weiser PT, Chang CY, McDonnell DP, Hanson RN. 4,4'-Unsymmetrically substituted 3,3'-biphenyl alpha helical proteomimetics as potential coactivator binding inhibitors. Bioorganic & Medicinal Chemistry. 22: 917-26. PMID 24360824 DOI: 10.1016/J.Bmc.2013.10.051 |
0.395 |
|
| 2014 |
Shatnawi A, Norris JD, Chaveroux C, Jasper JS, Sherk AB, McDonnell DP, Giguère V. ELF3 is a repressor of androgen receptor action in prostate cancer cells. Oncogene. 33: 862-71. PMID 23435425 DOI: 10.1038/Onc.2013.15 |
0.818 |
|
| 2014 |
Stevens EV, Whitaker R, Guinet A, Chang C, Grenier C, Marks J, McDonnell DP, Murphy SK, Berchuck A, Gaillard S. Abstract 4570: Role of ERRalpha in ovarian cancer Cancer Research. 74: 4570-4570. DOI: 10.1158/1538-7445.Am2014-4570 |
0.416 |
|
| 2014 |
Alfaqih MA, Nelson ER, Safi R, Jasper J, Chang C, Freedland SJ, McDonnell DP. Abstract 3311: The cholesterol/ 27-hydroxycholesterol axis is a novel therapeutic target in castrate resistant prostate cancer Cancer Research. 74: 3311-3311. DOI: 10.1158/1538-7445.Am2014-3311 |
0.404 |
|
| 2013 |
Nelson ER, Wardell SE, Jasper JS, Park S, Suchindran S, Howe MK, Carver NJ, Pillai RV, Sullivan PM, Sondhi V, Umetani M, Geradts J, McDonnell DP. 27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology. Science (New York, N.Y.). 342: 1094-8. PMID 24288332 DOI: 10.1126/Science.1241908 |
0.402 |
|
| 2013 |
Hu P, Herrmann R, Bednar A, Saloupis P, Dwyer MA, Yang P, Qi X, Thomas RS, Jaffe GJ, Boulton ME, McDonnell DP, Malek G. Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology. Proceedings of the National Academy of Sciences of the United States of America. 110: E4069-78. PMID 24106308 DOI: 10.1073/Pnas.1307574110 |
0.381 |
|
| 2013 |
Wardell SE, Nelson ER, Chao CA, McDonnell DP. Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2420-31. PMID 23536434 DOI: 10.1158/1078-0432.Ccr-12-3771 |
0.457 |
|
| 2013 |
Augello MA, Burd CJ, Birbe R, McNair C, Ertel A, Magee MS, Frigo DE, Wilder-Romans K, Shilkrut M, Han S, Jernigan DL, Dean JL, Fatatis A, McDonnell DP, Visakorpi T, et al. Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes. The Journal of Clinical Investigation. 123: 493-508. PMID 23257359 DOI: 10.1172/Jci64750 |
0.413 |
|
| 2013 |
Shi Y, Han JJ, Tennakoon JB, Mehta FF, Merchant FA, Burns AR, Howe MK, McDonnell DP, Frigo DE. Androgens promote prostate cancer cell growth through induction of autophagy. Molecular Endocrinology (Baltimore, Md.). 27: 280-95. PMID 23250485 DOI: 10.1210/Me.2012-1260 |
0.331 |
|
| 2013 |
Nelson ER, Wardell SE, McDonnell DP. The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosis. Bone. 53: 42-50. PMID 23168292 DOI: 10.1016/J.Bone.2012.11.011 |
0.455 |
|
| 2013 |
Nelson ER, Wardell SE, Howe MK, Carver NJ, Umetani M, McDonnell DP. Abstract PR3: The cholesterol metabolite 27-hydroxycholesterol increases breast cancer tumor growth and metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-Pr3 |
0.373 |
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| 2013 |
Wright TM, Wardell SE, Nelson ER, McDonnell DP. Abstract A96: The role of the proto-oncogene AGR2 in endocrine resistant breast cancer. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A96 |
0.422 |
|
| 2013 |
Wardell SE, McDonnell DP, Nelson ER. Regulation of Bone Cell Function by Estrogens Osteoporosis: Fourth Edition. 329-344. DOI: 10.1016/B978-0-12-415853-5.00014-5 |
0.427 |
|
| 2012 |
Chang CY, McDonnell DP. Molecular pathways: the metabolic regulator estrogen-related receptor α as a therapeutic target in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6089-95. PMID 23019305 DOI: 10.1158/1078-0432.Ccr-11-3221 |
0.5 |
|
| 2012 |
Weiser PT, Williams AB, Chang CY, McDonnell DP, Hanson RN. 3,3'-Disubstituted bipolar biphenyls as inhibitors of nuclear receptor coactivator binding. Bioorganic & Medicinal Chemistry Letters. 22: 6587-90. PMID 23017882 DOI: 10.1016/J.Bmcl.2012.09.007 |
0.405 |
|
| 2012 |
Wardell SE, Kazmin D, McDonnell DP. Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes. Molecular Endocrinology (Baltimore, Md.). 26: 1235-48. PMID 22570330 DOI: 10.1210/Me.2012-1031 |
0.553 |
|
| 2012 |
Pollock JA, Larrea MD, Jasper JS, McDonnell DP, McCafferty DG. Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners. Acs Chemical Biology. 7: 1221-31. PMID 22533360 DOI: 10.1021/Cb300108C |
0.439 |
|
| 2012 |
Malek G, Dwyer M, McDonnell D. Exploring the potential role of the oxidant-activated transcription factor aryl hydrocarbon receptor in the pathogenesis of AMD Advances in Experimental Medicine and Biology. 723: 51-59. PMID 22183315 DOI: 10.1007/978-1-4614-0631-0_8 |
0.353 |
|
| 2011 |
Michalek RD, Gerriets VA, Nichols AG, Inoue M, Kazmin D, Chang CY, Dwyer MA, Nelson ER, Pollizzi KN, Ilkayeva O, Giguere V, Zuercher WJ, Powell JD, Shinohara ML, McDonnell DP, et al. Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 108: 18348-53. PMID 22042850 DOI: 10.1073/Pnas.1108856108 |
0.361 |
|
| 2011 |
Chang CY, Kazmin D, Jasper JS, Kunder R, Zuercher WJ, McDonnell DP. The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer. Cancer Cell. 20: 500-10. PMID 22014575 DOI: 10.1016/J.Ccr.2011.08.023 |
0.458 |
|
| 2011 |
Nelson ER, DuSell CD, Wang X, Howe MK, Evans G, Michalek RD, Umetani M, Rathmell JC, Khosla S, Gesty-Palmer D, McDonnell DP. The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors. Endocrinology. 152: 4691-705. PMID 21933863 DOI: 10.1210/En.2011-1298 |
0.786 |
|
| 2011 |
Bodoor K, Lontay B, Safi R, Weitzel DH, Loiselle D, Wei Z, Lengyel S, McDonnell DP, Haystead TA. Smoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancy. The Journal of Biological Chemistry. 286: 31839-51. PMID 21771785 DOI: 10.1074/Jbc.M111.270397 |
0.463 |
|
| 2011 |
Wardell SE, Marks JR, McDonnell DP. The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy. Biochemical Pharmacology. 82: 122-30. PMID 21501600 DOI: 10.1016/J.Bcp.2011.03.031 |
0.526 |
|
| 2011 |
Dwyer MA, Kazmin D, Hu P, McDonnell DP, Malek G. Research resource: nuclear receptor atlas of human retinal pigment epithelial cells: potential relevance to age-related macular degeneration. Molecular Endocrinology (Baltimore, Md.). 25: 360-72. PMID 21239617 DOI: 10.1210/Me.2010-0392 |
0.437 |
|
| 2011 |
Yang J, Chang CY, Safi R, Morgan J, McDonnell DP, Fuller PJ, Clyne CD, Young MJ. Identification of ligand-selective peptide antagonists of the mineralocorticoid receptor using phage display. Molecular Endocrinology (Baltimore, Md.). 25: 32-43. PMID 21106883 DOI: 10.1210/Me.2010-0193 |
0.449 |
|
| 2011 |
Frigo DE, Howe MK, Wittmann BM, Brunner AM, Cushman I, Wang Q, Brown M, Means AR, McDonnell DP. CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells. Cancer Research. 71: 528-37. PMID 21098087 DOI: 10.1158/0008-5472.Can-10-2581 |
0.357 |
|
| 2011 |
Wade H, McDonnell D, Brown M. Abstract 4542: Dose-dependent effects of progestins on progesterone receptor activity and target gene expression: less is more Cancer Research. 71: 4542-4542. DOI: 10.1158/1538-7445.Am2011-4542 |
0.451 |
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| 2010 |
Kobayashi S, Stice JP, Kazmin D, Wittmann BM, Kimbrel EA, Edwards DP, Chang CY, McDonnell DP. Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer. Molecular Endocrinology (Baltimore, Md.). 24: 2292-302. PMID 20980435 DOI: 10.1210/Me.2010-0289 |
0.802 |
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| 2010 |
McDonnell DP, Wardell SE. The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer. Current Opinion in Pharmacology. 10: 620-8. PMID 20926342 DOI: 10.1016/J.Coph.2010.09.007 |
0.502 |
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| 2010 |
Dwyer MA, Joseph JD, Wade HE, Eaton ML, Kunder RS, Kazmin D, Chang CY, McDonnell DP. WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration. Cancer Research. 70: 9298-308. PMID 20870744 DOI: 10.1158/0008-5472.Can-10-0226 |
0.757 |
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| 2010 |
Orr CR, Montie HL, Liu Y, Bolzoni E, Jenkins SC, Wilson EM, Joseph JD, McDonnell DP, Merry DE. An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy. The Journal of Biological Chemistry. 285: 35567-77. PMID 20826791 DOI: 10.1074/Jbc.M110.146845 |
0.386 |
|
| 2010 |
DuSell CD, Nelson ER, Wang X, Abdo J, Mödder UI, Umetani M, Gesty-Palmer D, Javitt NB, Khosla S, McDonnell DP. The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. Endocrinology. 151: 3675-85. PMID 20501668 DOI: 10.1210/En.2010-0080 |
0.791 |
|
| 2010 |
Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Molecular and Cellular Biology. 30: 1866-77. PMID 20123965 DOI: 10.1128/Mcb.01060-09 |
0.767 |
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| 2010 |
Muramoto GG, Russell JL, Safi R, Salter AB, Himburg HA, Daher P, Meadows SK, Doan P, Storms RW, Chao NJ, McDonnell DP, Chute JP. Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. Stem Cells (Dayton, Ohio). 28: 523-34. PMID 20054864 DOI: 10.1002/Stem.299 |
0.307 |
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| 2010 |
Hall JM, Barhoover MA, Kazmin D, McDonnell DP, Greenlee WF, Thomas RS. Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation. Molecular Endocrinology (Baltimore, Md.). 24: 359-69. PMID 20032195 DOI: 10.1210/Me.2009-0346 |
0.694 |
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| 2010 |
Zhou XE, Suino-Powell K, Ludidi PL, McDonnell DP, Xu HE. Expression, purification and primary crystallographic study of human androgen receptor in complex with DNA and coactivator motifs. Protein Expression and Purification. 71: 21-7. PMID 19995608 DOI: 10.1016/J.Pep.2009.12.002 |
0.411 |
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| 2010 |
Chute JP, Ross JR, McDonnell DP. Minireview: Nuclear receptors, hematopoiesis, and stem cells. Molecular Endocrinology (Baltimore, Md.). 24: 1-10. PMID 19934345 DOI: 10.1210/Me.2009-0332 |
0.328 |
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| 2010 |
DuSell CD, Nelson ER, Wittmann BM, Fretz JA, Kazmin D, Thomas RS, Pike JW, McDonnell DP. Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators. Molecular Endocrinology (Baltimore, Md.). 24: 33-46. PMID 19901195 DOI: 10.1210/Me.2009-0339 |
0.858 |
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| 2010 |
Kobayashi S, Stice JP, Kazmin D, Wittmann BM, Kimbrel EA, Edwards DP, Chang C, McDonnell DP. Mechanisms of Progesterone Receptor Inhibition of Inflammatory Responses in Cellular Models of Breast Cancer Endocrine Reviews. 31: 5457-5457. DOI: 10.1210/Edrv.31.6.9984 |
0.78 |
|
| 2010 |
Hall JM, Barhoover MA, Kazmin D, McDonnell DP, Greenlee WF, Thomas RS. Activation of the Aryl-Hydrocarbon Receptor Inhibits Invasive and Metastatic Features of Human Breast Cancer Cells and Promotes Breast Cancer Cell Differentiation Endocrine Reviews. 31: 138-138. DOI: 10.1210/Edrv.31.1.9999 |
0.41 |
|
| 2009 |
Norris JD, Chang CY, Wittmann BM, Kunder RS, Cui H, Fan D, Joseph JD, McDonnell DP. The homeodomain protein HOXB13 regulates the cellular response to androgens. Molecular Cell. 36: 405-16. PMID 19917249 DOI: 10.1016/J.Molcel.2009.10.020 |
0.406 |
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| 2009 |
Joseph JD, Wittmann BM, Dwyer MA, Cui H, Dye DA, McDonnell DP, Norris JD. Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists. Proceedings of the National Academy of Sciences of the United States of America. 106: 12178-83. PMID 19574450 DOI: 10.1073/Pnas.0900185106 |
0.516 |
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| 2009 |
Frigo DE, Sherk AB, Wittmann BM, Norris JD, Wang Q, Joseph JD, Toner AP, Brown M, McDonnell DP. Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro. Molecular Endocrinology (Baltimore, Md.). 23: 1385-96. PMID 19460858 DOI: 10.1210/Me.2009-0010 |
0.795 |
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| 2009 |
Stein RA, Gaillard S, McDonnell DP. Estrogen-related receptor alpha induces the expression of vascular endothelial growth factor in breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 114: 106-12. PMID 19429439 DOI: 10.1016/J.Jsbmb.2009.02.010 |
0.476 |
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| 2009 |
Grasfeder LL, Gaillard S, Hammes SR, Ilkayeva O, Newgard CB, Hochberg RB, Dwyer MA, Chang CY, McDonnell DP. Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. Molecular Endocrinology (Baltimore, Md.). 23: 1171-82. PMID 19389810 DOI: 10.1210/Me.2009-0024 |
0.787 |
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| 2009 |
Norris JD, Joseph JD, Sherk AB, Juzumiene D, Turnbull PS, Rafferty SW, Cui H, Anderson E, Fan D, Dye DA, Deng X, Kazmin D, Chang CY, Willson TM, McDonnell DP. Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligands. Chemistry & Biology. 16: 452-60. PMID 19389631 DOI: 10.1016/J.Chembiol.2009.01.016 |
0.83 |
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| 2009 |
Clyne CD, Chang CY, Safi R, Fuller PJ, McDonnell DP, Young MJ. Purification and characterization of recombinant human mineralocorticoid receptor. Molecular and Cellular Endocrinology. 302: 81-5. PMID 19114086 DOI: 10.1016/J.Mce.2008.11.030 |
0.473 |
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| 2009 |
Safi R, Muramoto GG, Salter AB, Meadows S, Himburg H, Russell L, Daher P, Doan P, Leibowitz MD, Chao NJ, McDonnell DP, Chute JP. Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture. Molecular Endocrinology (Baltimore, Md.). 23: 188-201. PMID 19106195 DOI: 10.1210/Me.2008-0121 |
0.426 |
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| 2009 |
Wardell SE, Ilkayeva OR, Wieman HL, Frigo DE, Rathmell JC, Newgard CB, McDonnell DP. Glucose metabolism as a target of histone deacetylase inhibitors. Molecular Endocrinology (Baltimore, Md.). 23: 388-401. PMID 19106193 DOI: 10.1210/Jcem.94.2.9997 |
0.303 |
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| 2009 |
Collins NH, Lessey EC, DuSell CD, McDonnell DP, Fowler L, Palomino WA, Illera MJ, Yu X, Mo B, Houwing AM, Lessey BA. Characterization of antiestrogenic activity of the Chinese herb, prunella vulgaris, using in vitro and in vivo (Mouse Xenograft) models. Biology of Reproduction. 80: 375-83. PMID 18923163 DOI: 10.1095/Biolreprod.107.065375 |
0.815 |
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| 2008 |
Stein RA, Chang CY, Kazmin DA, Way J, Schroeder T, Wergin M, Dewhirst MW, McDonnell DP. Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer. Cancer Research. 68: 8805-12. PMID 18974123 DOI: 10.1158/0008-5472.Can-08-1594 |
0.507 |
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| 2008 |
Sherk AB, Frigo DE, Schnackenberg CG, Bray JD, Laping NJ, Trizna W, Hammond M, Patterson JR, Thompson SK, Kazmin D, Norris JD, McDonnell DP. Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic. Cancer Research. 68: 7475-83. PMID 18794135 DOI: 10.1158/0008-5472.Can-08-1047 |
0.788 |
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| 2008 |
DuSell CD, McDonnell DP. 27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling. Trends in Pharmacological Sciences. 29: 510-4. PMID 18722677 DOI: 10.1016/J.Tips.2008.07.003 |
0.851 |
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| 2008 |
Frigo DE, McDonnell DP. Differential effects of prostate cancer therapeutics on neuroendocrine transdifferentiation. Molecular Cancer Therapeutics. 7: 659-69. PMID 18347151 DOI: 10.1158/1535-7163.Mct-07-0480 |
0.38 |
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| 2008 |
DuSell CD, Umetani M, Shaul PW, Mangelsdorf DJ, McDonnell DP. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Molecular Endocrinology (Baltimore, Md.). 22: 65-77. PMID 17872378 DOI: 10.1210/Me.2007-0383 |
0.839 |
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| 2008 |
Grasfeder LL, McDonnell DP. Nuclear receptor cofactor interactions as targets for new drug discovery Nr Coregulators and Human Diseases. 572-599. DOI: 10.1142/9789812819178_0019 |
0.489 |
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| 2007 |
Hyatt SM, Lockamy EL, Stein RA, McDonnell DP, Miller AB, Orband-Miller LA, Willson TM, Zuercher WJ. On the intractability of estrogen-related receptor alpha as a target for activation by small molecules. Journal of Medicinal Chemistry. 50: 6722-4. PMID 18052088 DOI: 10.1021/Jm7012387 |
0.463 |
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| 2007 |
Wittmann BM, Sherk A, McDonnell DP. Definition of functionally important mechanistic differences among selective estrogen receptor down-regulators. Cancer Research. 67: 9549-60. PMID 17909066 DOI: 10.1158/0008-5472.Can-07-1590 |
0.85 |
|
| 2007 |
Mettu NB, Stanley TB, Dwyer MA, Jansen MS, Allen JE, Hall JM, McDonnell DP. The nuclear receptor-coactivator interaction surface as a target for peptide antagonists of the peroxisome proliferator-activated receptors. Molecular Endocrinology (Baltimore, Md.). 21: 2361-77. PMID 17595321 DOI: 10.1210/Me.2007-0201 |
0.839 |
|
| 2007 |
Hall JM, McDonnell DP. The molecular mechanisms underlying the proinflammatory actions of thiazolidinediones in human macrophages. Molecular Endocrinology (Baltimore, Md.). 21: 1756-68. PMID 17488971 DOI: 10.1210/Me.2007-0060 |
0.675 |
|
| 2007 |
Heldring N, Pawson T, McDonnell D, Treuter E, Gustafsson JA, Pike AC. Structural insights into corepressor recognition by antagonist-bound estrogen receptors. The Journal of Biological Chemistry. 282: 10449-55. PMID 17283072 DOI: 10.1074/Jbc.M611424200 |
0.465 |
|
| 2007 |
Zella LA, Chang CY, McDonnell DP, Pike JW. The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs. Archives of Biochemistry and Biophysics. 460: 206-12. PMID 17254542 DOI: 10.1016/J.Abb.2006.12.016 |
0.363 |
|
| 2007 |
Gaillard S, Dwyer MA, McDonnell DP. Definition of the molecular basis for estrogen receptor-related receptor-alpha-cofactor interactions. Molecular Endocrinology (Baltimore, Md.). 21: 62-76. PMID 17053040 DOI: 10.1210/Me.2006-0179 |
0.558 |
|
| 2007 |
Sherk AB, McDonnell DP. Molecular pharmacology of estrogen and progesterone receptors Menopause. 17-28. DOI: 10.1016/B978-012369443-0/50004-1 |
0.81 |
|
| 2006 |
Stein RA, McDonnell DP. Estrogen-related receptor α as a therapeutic target in cancer Endocrine-Related Cancer. 13. PMID 17259555 DOI: 10.1677/Erc.1.01292 |
0.543 |
|
| 2006 |
Gaillard S, Grasfeder LL, Haeffele CL, Lobenhofer EK, Chu TM, Wolfinger R, Kazmin D, Koves TR, Muoio DM, Chang CY, McDonnell DP. Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs. Molecular Cell. 24: 797-803. PMID 17157261 DOI: 10.1016/J.Molcel.2006.10.012 |
0.835 |
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| 2006 |
McDonnell DP. Mechanism-based discovery as an approach to identify the next generation of estrogen receptor modulators. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2432-4. PMID 17142791 DOI: 10.1096/Fj.06-1202Ufm |
0.547 |
|
| 2006 |
Lu NZ, Wardell SE, Burnstein KL, Defranco D, Fuller PJ, Giguere V, Hochberg RB, McKay L, Renoir JM, Weigel NL, Wilson EM, McDonnell DP, Cidlowski JA. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacological Reviews. 58: 782-97. PMID 17132855 DOI: 10.1124/Pr.58.4.9 |
0.503 |
|
| 2006 |
Zhang Y, Ma K, Sadana P, Chowdhury F, Gaillard S, Wang F, McDonnell DP, Unterman TG, Elam MB, Park EA. Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression. The Journal of Biological Chemistry. 281: 39897-906. PMID 17079227 DOI: 10.1074/Jbc.M608657200 |
0.405 |
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| 2006 |
Chute JP, Muramoto GG, Whitesides J, Colvin M, Safi R, Chao NJ, McDonnell DP. Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 11707-12. PMID 16857736 DOI: 10.1073/Pnas.0603806103 |
0.34 |
|
| 2006 |
Noble SM, Carnahan VE, Moore LB, Luntz T, Wang H, Ittoop OR, Stimmel JB, Davis-Searles PR, Watkins RE, Wisely GB, LeCluyse E, Tripathy A, McDonnell DP, Redinbo MR. Human PXR forms a tryptophan zipper-mediated homodimer. Biochemistry. 45: 8579-89. PMID 16834332 DOI: 10.1021/Bi0602821 |
0.483 |
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| 2006 |
Kazmin D, Prytkova T, Cook CE, Wolfinger R, Chu TM, Beratan D, Norris JD, Chang CY, McDonnell DP. Linking ligand-induced alterations in androgen receptor structure to differential gene expression: A first step in the rational design of selective androgen receptor modulators Molecular Endocrinology. 20: 1201-1217. PMID 16574741 DOI: 10.1210/Me.2005-0309 |
0.472 |
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| 2006 |
Chao EY, Collins JL, Gaillard S, Miller AB, Wang L, Orband-Miller LA, Nolte RT, McDonnell DP, Willson TM, Zuercher WJ. Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma. Bioorganic & Medicinal Chemistry Letters. 16: 821-4. PMID 16307879 DOI: 10.1016/J.Bmcl.2005.11.030 |
0.42 |
|
| 2006 |
Stein R, Way JM, McDonnell DP, Zuercher WJ. Estrogen-related receptor α as a therapeutic target Drugs of the Future. 31: 427-436. DOI: 10.1358/Dof.2006.031.05.994706 |
0.42 |
|
| 2006 |
Muramoto GG, Safi R, Salter A, Himburg H, Chao NJ, McDonnell D, Chute JP. The Retinoid X Receptor Regulates Human Hematopoietic Stem Cell Fate. Blood. 108: 1324-1324. DOI: 10.1182/Blood.V108.11.1324.1324 |
0.372 |
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| 2005 |
Juzumiene D, Chang CY, Fan D, Hartney T, Norris JD, McDonnell DP. Single-step purification of full-length human androgen receptor. Nuclear Receptor Signaling. 3: e001. PMID 16604169 DOI: 10.1621/Nrs.03001 |
0.462 |
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| 2005 |
Hall JM, McDonnell DP. Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting. Molecular Interventions. 5: 343-57. PMID 16394250 DOI: 10.1124/Mi.5.6.7 |
0.709 |
|
| 2005 |
Safi R, Kovacic A, Gaillard S, Murata Y, Simpson ER, McDonnell DP, Clyne CD. Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest a novel target for breast-specific antiestrogen therapy. Cancer Research. 65: 11762-70. PMID 16357189 DOI: 10.1158/0008-5472.Can-05-2792 |
0.527 |
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| 2005 |
Solomon IH, Hager JM, Safi R, McDonnell DP, Redinbo MR, Ortlund EA. Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity. Journal of Molecular Biology. 354: 1091-102. PMID 16289203 DOI: 10.1016/J.Jmb.2005.10.009 |
0.395 |
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| 2005 |
Chang CY, Abdo J, Hartney T, McDonnell DP. Development of peptide antagonists for the androgen receptor using combinatorial peptide phage display. Molecular Endocrinology (Baltimore, Md.). 19: 2478-90. PMID 16051662 DOI: 10.1210/Me.2005-0072 |
0.516 |
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| 2005 |
Wu YL, Yang X, Ren Z, McDonnell DP, Norris JD, Willson TM, Greene GL. Structural basis for an unexpected mode of SERM-Mediated ER antagonism Molecular Cell. 18: 413-424. PMID 15893725 DOI: 10.1016/J.Molcel.2005.04.014 |
0.43 |
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| 2005 |
Chang CY, McDonnell DP. Androgen receptor-cofactor interactions as targets for new drug discovery. Trends in Pharmacological Sciences. 26: 225-8. PMID 15860367 DOI: 10.1016/J.Tips.2005.03.002 |
0.501 |
|
| 2005 |
Zuercher WJ, Gaillard S, Orband-Miller LA, Chao EY, Shearer BG, Jones DG, Miller AB, Collins JL, McDonnell DP, Willson TM. Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma. Journal of Medicinal Chemistry. 48: 3107-9. PMID 15857113 DOI: 10.1021/Jm050161J |
0.547 |
|
| 2005 |
Ortlund EA, Lee Y, Solomon IH, Hager JM, Safi R, Choi Y, Guan Z, Tripathy A, Raetz CR, McDonnell DP, Moore DD, Redinbo MR. Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP. Nature Structural & Molecular Biology. 12: 357-63. PMID 15723037 DOI: 10.1038/Nsmb910 |
0.505 |
|
| 2005 |
Shaffer PL, McDonnell DP, Gewirth DT. Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor. Biochemistry. 44: 2678-85. PMID 15709781 DOI: 10.1021/Bi0477182 |
0.416 |
|
| 2005 |
McDonnell DP. The molecular pharmacology of estrogen receptor modulators: implications for the treatment of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 871s-7s. PMID 15701880 |
0.42 |
|
| 2005 |
Chute JP, Muramoto GG, Whitesides J, Colvin M, Saffi R, Chao NJ, McDonnell D. Modulation of Aldehyde Dehydrogenase and Retinoid Signaling Induces the Expansion of Human Hematopoietic Stem Cells. Blood. 106: 1713-1713. DOI: 10.1182/Blood.V106.11.1713.1713 |
0.345 |
|
| 2004 |
McDonnell DP. The molecular determinants of estrogen receptor pharmacology. Maturitas. 48: S7-12. PMID 15337242 DOI: 10.1016/J.Maturitas.2004.03.006 |
0.582 |
|
| 2004 |
Shao W, Keeton EK, McDonnell DP, Brown M. Coactivator AIB1 links estrogen receptor transcriptional activity and stability. Proceedings of the National Academy of Sciences of the United States of America. 101: 11599-604. PMID 15289619 DOI: 10.1073/Pnas.0402997101 |
0.488 |
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| 2004 |
Turgeon JL, McDonnell DP, Martin KA, Wise PM. Hormone therapy: physiological complexity belies therapeutic simplicity. Science (New York, N.Y.). 304: 1269-73. PMID 15166356 DOI: 10.1126/Science.1096725 |
0.348 |
|
| 2004 |
Jansen MS, Nagel SC, Miranda PJ, Lobenhofer EK, Afshari CA, McDonnell DP. Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition. Proceedings of the National Academy of Sciences of the United States of America. 101: 7199-204. PMID 15103026 DOI: 10.1073/Pnas.0402014101 |
0.475 |
|
| 2004 |
Glass CK, McDonnell DP. The jensen symposium; a tribute to a pioneer in the field of nuclear receptor biology. Molecular Cell. 13: 459-67. PMID 14992717 DOI: 10.1016/S1097-2765(04)00093-0 |
0.476 |
|
| 2004 |
Kurebayashi S, Nakajima T, Kim SC, Chang CY, McDonnell DP, Renaud JP, Jetten AM. Selective LXXLL peptides antagonize transcriptional activation by the retinoid-related orphan receptor RORgamma. Biochemical and Biophysical Research Communications. 315: 919-27. PMID 14985100 DOI: 10.1016/J.Bbrc.2004.01.131 |
0.439 |
|
| 2004 |
Tirado OM, Selva DM, Toràn N, Suárez-Quian CA, Jansen M, McDonnell DP, Reventós J, Munell F. Increased expression of estrogen receptor beta in pachytene spermatocytes after short-term methoxyacetic acid administration. Journal of Andrology. 25: 84-94. PMID 14662790 DOI: 10.1002/J.1939-4640.2004.Tb02762.X |
0.419 |
|
| 2003 |
Sathya G, Chang CY, Kazmin D, Cook CE, McDonnell DP. Pharmacological uncoupling of androgen receptor-mediated prostate cancer cell proliferation and prostate-specific antigen secretion. Cancer Research. 63: 8029-36. PMID 14633736 |
0.414 |
|
| 2003 |
Chang CY, Norris JD, Jansen M, Huang HJ, McDonnell DP. Application of random peptide phage display to the study of nuclear hormone receptors. Methods in Enzymology. 364: 118-42. PMID 14631842 DOI: 10.1016/S0076-6879(03)64007-3 |
0.385 |
|
| 2003 |
McDonnell DP. Mining the complexities of the estrogen signaling pathways for novel therapeutics. Endocrinology. 144: 4237-40. PMID 14500558 DOI: 10.1210/En.2003-0900 |
0.318 |
|
| 2003 |
Rincavage HL, McDonnell DP, Kuhn CM. Expression of functional estrogen receptor beta in locus coeruleus-derived Cath.a cells. Endocrinology. 144: 2829-35. PMID 12810537 DOI: 10.1210/En.2002-221120 |
0.489 |
|
| 2003 |
Pike JW, Pathrose P, Barmina O, Chang CY, McDonnell DP, Yamamoto H, Shevde NK. Synthetic LXXLL peptide antagonize 1,25-dihydroxyvitamin D3-dependent transcription. Journal of Cellular Biochemistry. 88: 252-8. PMID 12520523 DOI: 10.1002/Jcb.10336 |
0.31 |
|
| 2003 |
Kimbrel EA, McDonnell DP. Function and mode of action of nuclear receptors: Estrogen, progesterone, and vitamin D Pure and Applied Chemistry. 75: 1671-1683. DOI: 10.1351/Pac200375111671 |
0.821 |
|
| 2002 |
Sathya G, Jansen MS, Nagel SC, Cook CE, McDonnell DP. Identification and Characterization of Novel Estrogen Receptor-β-Sparing Antiprogestins. Endocrinology. 143: 3071-3082. PMID 28201467 DOI: 10.1210/endo.143.8.8942 |
0.322 |
|
| 2002 |
Safe SH, Pallaroni L, Yoon K, Gaido K, Ross S, McDonnell D. Problems for risk assessment of endocrine-active estrogenic compounds. Environmental Health Perspectives. 110: 925-9. PMID 12634121 DOI: 10.1289/Ehp.02110S6925 |
0.535 |
|
| 2002 |
Pathrose P, Barmina O, Chang CY, McDonnell DP, Shevde NK, Pike JW. Inhibition of 1,25-dihydroxyvitamin D3-dependent transcription by synthetic LXXLL peptide antagonists that target the activation domains of the vitamin D and retinoid X receptors. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 2196-205. PMID 12469913 DOI: 10.1359/Jbmr.2002.17.12.2196 |
0.365 |
|
| 2002 |
Huang HJ, Norris JD, McDonnell DP. Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists. Molecular Endocrinology (Baltimore, Md.). 16: 1778-92. PMID 12145334 DOI: 10.1210/Me.2002-0089 |
0.509 |
|
| 2002 |
Sathya G, Jansen MS, Nagel SC, Cook CE, McDonnell DP. Identification and characterization of novel estrogen receptor-beta-sparing antiprogestins. Endocrinology. 143: 3071-82. PMID 12130573 DOI: 10.1210/Endo.143.8.8942 |
0.575 |
|
| 2002 |
McDonnell DP, Wijayaratne A, Chang CY, Norris JD. Elucidation of the molecular mechanism of action of selective estrogen receptor modulators. The American Journal of Cardiology. 90: 35F-43F. PMID 12106639 DOI: 10.1016/S0002-9149(01)02221-4 |
0.832 |
|
| 2002 |
Li X, Kimbrel EA, Kenan DJ, McDonnell DP. Direct interactions between corepressors and coactivators permit the integration of nuclear receptor-mediated repression and activation. Molecular Endocrinology (Baltimore, Md.). 16: 1482-91. PMID 12089344 DOI: 10.1210/Mend.16.7.0860 |
0.781 |
|
| 2002 |
McDonnell DP, Norris JD. Connections and regulation of the human estrogen receptor. Science (New York, N.Y.). 296: 1642-4. PMID 12040178 DOI: 10.1126/Science.1071884 |
0.567 |
|
| 2002 |
McDonnell DP, Connor CE, Wijayaratne A, Chang CY, Norris JD. Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators. Recent Progress in Hormone Research. 57: 295-316. PMID 12017549 DOI: 10.1210/Rp.57.1.295 |
0.821 |
|
| 2002 |
Li X, McDonnell DP. The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT. Molecular and Cellular Biology. 22: 3663-73. PMID 11997503 DOI: 10.1128/Mcb.22.11.3663-3673.2002 |
0.343 |
|
| 2002 |
Herrington DM, Howard TD, Brosnihan KB, McDonnell DP, Li X, Hawkins GA, Reboussin DM, Xu J, Zheng SL, Meyers DA, Bleecker ER. Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. Circulation. 105: 1879-82. PMID 11997270 DOI: 10.1161/01.Cir.0000016173.98826.88 |
0.432 |
|
| 2002 |
Chang CY, McDonnell DP. Evaluation of ligand-dependent changes in AR structure using peptide probes. Molecular Endocrinology (Baltimore, Md.). 16: 647-60. PMID 11923463 DOI: 10.1210/Mend.16.4.0818 |
0.412 |
|
| 2002 |
Weatherman RV, Chang CY, Clegg NJ, Carroll DC, Day RN, Baxter JD, McDonnell DP, Scanlan TS, Schaufele F. Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer. Molecular Endocrinology (Baltimore, Md.). 16: 487-96. PMID 11875107 DOI: 10.1210/Mend.16.3.0813 |
0.471 |
|
| 2002 |
Hall JM, McDonnell DP, Korach KS. Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements. Molecular Endocrinology (Baltimore, Md.). 16: 469-86. PMID 11875105 DOI: 10.1210/Mend.16.3.0814 |
0.725 |
|
| 2002 |
Norris JD, Fan D, Sherk A, McDonnell DP. A negative coregulator for the human ER. Molecular Endocrinology (Baltimore, Md.). 16: 459-68. PMID 11875103 DOI: 10.1210/Mend.16.3.0787 |
0.818 |
|
| 2002 |
McDonnell DP, Chang CY, Norris JD. Capitalizing on the complexities of estrogen receptor pharmacology in the quest for the perfect SERM. Annals of the New York Academy of Sciences. 949: 16-35. PMID 11795348 DOI: 10.1111/J.1749-6632.2001.Tb03999.X |
0.483 |
|
| 2001 |
Nagel SC, Hagelbarger JL, McDonnell DP. Development of an ER action indicator mouse for the study of estrogens, selective ER modulators (SERMs), and Xenobiotics. Endocrinology. 142: 4721-8. PMID 11606437 DOI: 10.1210/Endo.142.11.8471 |
0.506 |
|
| 2001 |
Wijayaratne AL, McDonnell DP. The human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulators. The Journal of Biological Chemistry. 276: 35684-92. PMID 11473106 DOI: 10.1074/Jbc.M101097200 |
0.842 |
|
| 2001 |
Norris JD, Chang C, McDonnell DP. Estrogen receptor-cofactor interactions as targets for novel drug discovery Ernst Schering Research Foundation Workshop. 181-201. PMID 11394045 DOI: 10.1007/978-3-662-04645-6_10 |
0.332 |
|
| 2001 |
Hamilton MH, Tcherepanova I, Huibregtse JM, McDonnell DP. Nuclear Import/Export of hRPF1/Nedd4 Regulates the Ubiquitin-dependent Degradation of Its Nuclear Substrates Journal of Biological Chemistry. 276: 26324-26331. PMID 11342538 DOI: 10.1074/Jbc.M101205200 |
0.33 |
|
| 2001 |
Connor CE, Norris JD, Broadwater G, Willson TM, Gottardis MM, Dewhirst MW, McDonnell DP. Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor. Cancer Research. 61: 2917-22. PMID 11306468 |
0.732 |
|
| 2001 |
McDonnell DP, Chang CY, Norris JD. Development of peptide antagonists that target estrogen receptor-cofactor interactions. The Journal of Steroid Biochemistry and Molecular Biology. 74: 327-35. PMID 11162941 DOI: 10.1016/S0960-0760(00)00109-6 |
0.529 |
|
| 2000 |
Schaufele F, Chang Cy, Liu W, Baxter JD, Nordeen SK, Wan Y, Day RN, McDonnell DP. Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor Molecular Endocrinology. 14: 2024-2039. PMID 11117532 DOI: 10.1210/Mend.14.12.0572 |
0.446 |
|
| 2000 |
Hall JM, Chang CY, McDonnell DP. Development of peptide antagonists that target estrogen receptor beta-coactivator interactions. Molecular Endocrinology (Baltimore, Md.). 14: 2010-23. PMID 11117531 DOI: 10.1210/Mend.14.12.0561 |
0.681 |
|
| 2000 |
Gaido KW, Maness SC, McDonnell DP, Dehal SS, Kupfer D, Safe S. Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies. Molecular Pharmacology. 58: 852-8. PMID 10999957 |
0.427 |
|
| 2000 |
Giangrande PH, Kimbrel EA, Edwards DP, McDonnell DP. The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Molecular and Cellular Biology. 20: 3102-15. PMID 10757795 DOI: 10.1128/Mcb.20.9.3102-3115.2000 |
0.819 |
|
| 2000 |
Tcherepanova I, Puigserver P, Norris JD, Spiegelman BM, McDonnell DP. Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. The Journal of Biological Chemistry. 275: 16302-8. PMID 10748020 DOI: 10.1074/Jbc.M001364200 |
0.488 |
|
| 2000 |
McDonnell DP. Selective estrogen receptor modulators (SERMs): A first step in the development of perfect hormone replacement therapy regimen Journal of the Society For Gynecologic Investigation. 7. PMID 10732322 DOI: 10.1016/S1071-5576(99)00055-6 |
0.55 |
|
| 2000 |
McDonnell DP. Selective Estrogen Receptor Modulators (SERMs): A First Step in the Development of Perfect Hormone Replacement Therapy Regimen Journal of the Society For Gynecologic Investigation. 7: S10-S15. DOI: 10.1177/1071557600007001S05 |
0.348 |
|
| 2000 |
Gaido KW, Maness SC, McDonnell DP, Dehal SS, Kupfer D, Safe S. Interaction of Methoxychlor and Related Compounds with Estrogen Receptor α and β, and Androgen Receptor: Structure-Activity Studies Molecular Pharmacology. 58: 852-858. DOI: 10.1124/Mol.58.4.852 |
0.518 |
|
| 1999 |
Wijayaratne AL, Nagel SC, Paige LA, Christensen DJ, Norris JD, Fowlkes DM, McDonnell DP. Comparative Analyses of Mechanistic Differences Among Antiestrogens1. Endocrinology. 140: 5828-5840. PMID 28200824 DOI: 10.1210/endo.140.12.7164 |
0.743 |
|
| 1999 |
Hall JM, McDonnell DP. The Estrogen Receptor β-Isoform (ERβ) of the Human Estrogen Receptor Modulates ERα Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens1. Endocrinology. 140: 5566-5578. PMID 28200448 DOI: 10.1210/endo.140.12.7179 |
0.451 |
|
| 1999 |
Wijayaratne AL, Nagel SC, Paige LA, Christensen DJ, Norris JD, Fowlkes DM, McDonnell DP. Comparative analyses of mechanistic differences among antiestrogens. Endocrinology. 140: 5828-40. PMID 10579349 DOI: 10.1210/Endo.140.12.7164 |
0.83 |
|
| 1999 |
Gaido KW, Leonard LS, Maness SC, Hall JM, McDonnell DP, Saville B, Safe S. Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta. Endocrinology. 140: 5746-53. PMID 10579340 DOI: 10.1210/Endo.140.12.7191 |
0.7 |
|
| 1999 |
Hall JM, McDonnell DP. The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens. Endocrinology. 140: 5566-78. PMID 10579320 DOI: 10.1210/Endo.140.12.7179 |
0.727 |
|
| 1999 |
Chang CY, Norris JD, Grøn H, Paige LA, Hamilton PT, Kenan DJ, Fowlkes D, McDonnell DP. Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β Molecular and Cellular Biology. 19: 8226-8239. PMID 10567548 DOI: 10.1128/Mcb.19.12.8226 |
0.537 |
|
| 1999 |
Norris JD, Paige LA, Christensen DJ, Chang CY, Huacani MR, Fan D, Hamilton PT, Fowlkes DM, McDonnell DP. Peptide antagonists of the human estrogen receptor. Science (New York, N.Y.). 285: 744-6. PMID 10426998 DOI: 10.1126/Science.285.5428.744 |
0.546 |
|
| 1999 |
Tetel MJ, Giangrande PH, Leonhardt SA, McDonnell DP, Edwards DP. Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo. Molecular Endocrinology (Baltimore, Md.). 13: 910-24. PMID 10379890 DOI: 10.1210/Mend.13.6.0300 |
0.389 |
|
| 1999 |
Improta-Brears T, Whorton AR, Codazzi F, York JD, Meyer T, McDonnell DP. Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium. Proceedings of the National Academy of Sciences of the United States of America. 96: 4686-91. PMID 10200323 DOI: 10.1073/pnas.96.8.4686 |
0.357 |
|
| 1999 |
Paige LA, Christensen DJ, Grøn H, Norris JD, Gottlin EB, Padilla KM, Chang CY, Ballas LM, Hamilton PT, McDonnell DP, Fowlkes DM. Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta. Proceedings of the National Academy of Sciences of the United States of America. 96: 3999-4004. PMID 10097152 DOI: 10.1073/Pnas.96.7.3999 |
0.524 |
|
| 1999 |
Wagner BL, Pollio G, Giangrande P, Webster JC, Breslin M, Mais DE, Cook CE, Vedeckis WV, Cidlowski JA, McDonnell DP. The novel progesterone receptor antagonists RTI 3021-012 and RTI 3021-022 exhibit complex glucocorticoid receptor antagonist activities: implications for the development of dissociated antiprogestins. Endocrinology. 140: 1449-58. PMID 10067874 DOI: 10.1210/Endo.140.3.6581 |
0.538 |
|
| 1998 |
McDonnell DP. Definition of the molecular mechanism of action of tissue-selective oestrogen-receptor modulators Biochemical Society Transactions. 26: 54-60. PMID 10909757 DOI: 10.1042/Bst0260054 |
0.445 |
|
| 1998 |
Gould JC, Leonard LS, Maness SC, Wagner BL, Conner K, Zacharewski T, Safe S, McDonnell DP, Gaido KW. Bisphenol A interacts with the estrogen receptor alpha in a distinct manner from estradiol. Molecular and Cellular Endocrinology. 142: 203-14. PMID 9783916 DOI: 10.1016/S0303-7207(98)00084-7 |
0.461 |
|
| 1998 |
Maness SC, McDonnell DP, Gaido KW. Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. Toxicology and Applied Pharmacology. 151: 135-42. PMID 9705896 DOI: 10.1006/Taap.1998.8431 |
0.486 |
|
| 1998 |
Norris JD, Fan D, Stallcup MR, McDonnell DP. Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 highlights the role of activation function 2 in determining estrogen receptor pharmacology Journal of Biological Chemistry. 273: 6679-6688. PMID 9506965 DOI: 10.1074/Jbc.273.12.6679 |
0.555 |
|
| 1998 |
Wagner BL, Norris JD, Knotts TA, Weigel NL, McDonnell DP. The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor. Molecular and Cellular Biology. 18: 1369-78. PMID 9488452 DOI: 10.1128/Mcb.18.3.1369 |
0.566 |
|
| 1997 |
Giangrande PH, Pollio G, McDonnell DP. Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor Journal of Biological Chemistry. 272: 32889-32900. PMID 9407067 DOI: 10.1074/Jbc.272.52.32889 |
0.499 |
|
| 1997 |
Ramamoorthy K, Vyhlidal C, Wang F, Chen I, Safe S, McDonnell DP, Leonard LS, Gaido KW. Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. Toxicology and Applied Pharmacology. 147: 93-100. PMID 9356311 DOI: 10.1006/Taap.1997.8281 |
0.429 |
|
| 1997 |
Coldham NG, Dave M, Sivapathasundaram S, McDonnell DP, Connor C, Sauer MJ. Evaluation of a recombinant yeast cell estrogen screening assay. Environmental Health Perspectives. 105: 734-42. PMID 9294720 DOI: 10.1289/Ehp.97105734 |
0.722 |
|
| 1997 |
Willson TM, Norris JD, Wagner BL, Asplin I, Baer P, Brown HR, Jones SA, Henke B, Sauls H, Wolfe S, Morris DC, McDonnell DP. Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone. Endocrinology. 138: 3901-11. PMID 9275080 DOI: 10.1210/Endo.138.9.5358 |
0.508 |
|
| 1997 |
McDonnell DP, Norris JD. Analysis of the molecular pharmacology of estrogen receptor agonists and antagonists provides insights into the mechanism of action of estrogen in bone Osteoporosis International. 7: 29-34. PMID 9205643 DOI: 10.1007/Bf01674810 |
0.491 |
|
| 1997 |
Norris JD, Fan D, Kerner SA, McDonnell DP. Identification of a third autonomous activation domain within the human estrogen receptor Molecular Endocrinology. 11: 747-754. PMID 9171238 DOI: 10.1210/Mend.11.6.0008 |
0.486 |
|
| 1997 |
Ramamoorthy K, Wang F, Chen IC, Norris JD, McDonnell DP, Leonard LS, Gaido KW, Bocchinfuso WP, Korach KS, Safe S. Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism. Endocrinology. 138: 1520-7. PMID 9075711 DOI: 10.1210/Endo.138.4.5056 |
0.427 |
|
| 1997 |
Gaido KW, Leonard LS, Lovell S, Gould JC, Babaï D, Portier CJ, McDonnell DP. Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. Toxicology and Applied Pharmacology. 143: 205-12. PMID 9073609 DOI: 10.1006/Taap.1996.8069 |
0.51 |
|
| 1997 |
Marks JR, Huper G, Vaughn JP, Davis PL, Norris J, McDonnell DP, Wiseman RW, Futreal PA, Iglehart JD. BRCA1 expression is not directly responsive to estrogen Oncogene. 14: 115-121. PMID 9010238 DOI: 10.1038/Sj.Onc.1200808 |
0.453 |
|
| 1997 |
Ramamoorthy K, Wang F, Chen IC, Safe S, Norris JD, McDonnell DP, Gaido KW, Korach KS, McLachlan JA, Arnold SF, Klotz DM, Collins BM, Vonier PM, Guillette LJ. Potency of combined estrogenic pesticides Science. 275: 405-406. PMID 9005556 DOI: 10.1126/Science.275.5298.405 |
0.409 |
|
| 1996 |
Norris JD, Fan D, Wagner BL, McDonnell DP. Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity Molecular Endocrinology. 10: 1605-1616. PMID 8961270 DOI: 10.1210/Mend.10.12.8961270 |
0.502 |
|
| 1996 |
Vegeto E, Wagner BL, Imhof MO, McDonnell DP. The molecular pharmacology of ovarian steroid receptors. Vitamins and Hormones. 52: 99-128. PMID 8909158 DOI: 10.1016/S0083-6729(08)60408-2 |
0.465 |
|
| 1996 |
Wagner BL, Pollio G, Leonhardt S, Wani MC, Lee DY, Imhof MO, Edwards DP, Cook CE, McDonnell DP. 16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity. Proceedings of the National Academy of Sciences of the United States of America. 93: 8739-44. PMID 8710941 DOI: 10.1073/Pnas.93.16.8739 |
0.538 |
|
| 1996 |
Imhof MO, McDonnell DP. Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors Molecular and Cellular Biology. 16: 2594-2605. PMID 8649367 DOI: 10.1128/Mcb.16.6.2594 |
0.487 |
|
| 1996 |
McDonnell DP, Clemm DL, Hermann T, Goldman ME, Pike JW. Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. Molecular Endocrinology (Baltimore, Md.). 9: 659-69. PMID 8592512 DOI: 10.1210/Mend.9.6.8592512 |
0.551 |
|
| 1995 |
Klein KO, Baron J, Colli MJ, McDonnell DP, Cutler GB. Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay. The Journal of Clinical Investigation. 94: 2475-80. PMID 7989605 DOI: 10.1172/Jci117616 |
0.383 |
|
| 1995 |
Clemm DL, Macy BL, Santiso-Mere D, McDonnell DP. Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor. The Journal of Steroid Biochemistry and Molecular Biology. 53: 487-95. PMID 7626499 DOI: 10.1016/0960-0760(95)00095-H |
0.58 |
|
| 1995 |
McDonnell DP, Dana SL, Hoener PA, Lieberman BA, Imhof MO, Stein RB. Cellular mechanisms which distinguish between hormone- and antihormone-activated estrogen receptor. Annals of the New York Academy of Sciences. 761: 121-37. PMID 7625716 DOI: 10.1111/J.1749-6632.1995.Tb31374.X |
0.555 |
|
| 1995 |
Norris J, Fan D, Aleman C, Marks JR, Futreal PA, Wiseman RW, Iglehart JD, Deininger PL, McDonnell DP. Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers. The Journal of Biological Chemistry. 270: 22777-82. PMID 7559405 DOI: 10.1074/Jbc.270.39.22777 |
0.528 |
|
| 1995 |
McDonnell DP. Unraveling the human progesterone receptor signal transduction pathway. Insights into antiprogestin action Trends in Endocrinology and Metabolism. 6: 133-138. DOI: 10.1016/1043-2760(95)00065-P |
0.581 |
|
| 1995 |
Wen DX, McDonnell DP. Advances in our understanding of ligand-activated nuclear receptors Current Opinion in Biotechnology. 6: 582-589. DOI: 10.1016/0958-1669(95)80096-4 |
0.493 |
|
| 1994 |
McDonnell DP, Shahbaz MM, Vegeto E, Goldman ME. The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional activity. The Journal of Steroid Biochemistry and Molecular Biology. 48: 425-32. PMID 8180103 DOI: 10.1016/0960-0760(94)90190-2 |
0.538 |
|
| 1994 |
Tzukerman MT, Esty A, Santiso-Mere D, Danielian P, Parker MG, Stein RB, Pike JW, McDonnell DP. Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Molecular Endocrinology (Baltimore, Md.). 8: 21-30. PMID 8152428 DOI: 10.1210/Mend.8.1.8152428 |
0.466 |
|
| 1994 |
McDonnell DP, Clevenger B, Dana S, Santiso-Mere D, Tzukerman MT, Gleeson MA. The mechanism of action of steroid hormones: a new twist to an old tale. Journal of Clinical Pharmacology. 33: 1165-72. PMID 8126251 DOI: 10.1002/J.1552-4604.1993.Tb03916.X |
0.54 |
|
| 1994 |
Crombie DL, Mukherjee R, McDonnell DP, Hayes JS, Wang MW. Creatine kinase activity as an indicator of unopposed estrogen action in the mouse uterus associated with anti-progesterone treatment Journal of Steroid Biochemistry and Molecular Biology. 49: 123-129. PMID 8031708 DOI: 10.1016/0960-0760(94)90002-7 |
0.487 |
|
| 1994 |
Mukherjee R, Jow L, Noonan D, McDonnell DP. Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators Journal of Steroid Biochemistry and Molecular Biology. 51: 157-166. PMID 7981125 DOI: 10.1016/0960-0760(94)90089-2 |
0.4 |
|
| 1994 |
Wen DX, Xu YF, Mais DE, Goldman ME, McDonnell DP. The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells. Molecular and Cellular Biology. 14: 8356-64. PMID 7969170 DOI: 10.1128/Mcb.14.12.8356 |
0.546 |
|
| 1994 |
Dana SL, Hoener PA, Wheeler DA, Lawrence CB, McDonnell DP. Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells Molecular Endocrinology. 8: 1193-1207. PMID 7838152 DOI: 10.1210/Mend.8.9.7838152 |
0.508 |
|
| 1994 |
Tai PK, Albers MW, McDonnell DP, Chang H, Schreiber SL, Faber LE. Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506. Biochemistry. 33: 10666-71. PMID 7521210 DOI: 10.1021/Bi00201A014 |
0.493 |
|
| 1993 |
Nawaz Z, Stancel GM, McDonnell DP, Hyder SM. Creation of an active estrogen-responsive element by a single base change in the flanking sequence of a cellular oncogene: A possible mechanism for hormonal carcinogenesis? Molecular Carcinogenesis. 7: 76-82. PMID 8457291 DOI: 10.1002/Mc.2940070204 |
0.451 |
|
| 1993 |
Santiso-Mere D, Sone T, Hilliard GM, Pike JW, McDonnell DP. Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems. Molecular Endocrinology (Baltimore, Md.). 7: 833-9. PMID 8413308 DOI: 10.1210/Mend.7.7.8413308 |
0.443 |
|
| 1993 |
Poletti A, Conneely OM, McDonnell DP, Schrader WT, O'Malley BW, Weigel NL. Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites. Biochemistry. 32: 9563-9. PMID 8373763 DOI: 10.1021/Bi00088A007 |
0.459 |
|
| 1993 |
Vegeto E, Shahbaz MM, Wen DX, Goldman ME, O'Malley BW, McDonnell DP. Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Molecular Endocrinology (Baltimore, Md.). 7: 1244-55. PMID 8264658 DOI: 10.1210/Mend.7.10.8264658 |
0.611 |
|
| 1993 |
McDonnell DP, Vegeto E, Gleeson MA. Nuclear hormone receptors as targets for new drug discovery. Bio/Technology (Nature Publishing Company). 11: 1256-61. PMID 7764187 DOI: 10.1038/Nbt1193-1256 |
0.521 |
|
| 1992 |
Pham TA, McDonnell DP, Tsai MJ, O'Malley BW. Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes. Biochemistry. 31: 1570-8. PMID 1737013 DOI: 10.1021/Bi00120A039 |
0.582 |
|
| 1992 |
Vegeto E, Allan GF, Schrader WT, Tsai MJ, McDonnell DP, O'Malley BW. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell. 69: 703-13. PMID 1586949 DOI: 10.1016/0092-8674(92)90234-4 |
0.605 |
|
| 1992 |
Pham TA, Hwung YP, Santiso-Mere D, McDonnell DP, O'Malley BW. Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Molecular Endocrinology (Baltimore, Md.). 6: 1043-50. PMID 1508220 DOI: 10.1210/Mend.6.7.1508220 |
0.632 |
|
| 1992 |
Wooge CH, Nilsson GM, Heierson A, McDonnell DP, Katzenellenbogen BS. Structural requirements for high affinity ligand binding by estrogen receptors: a comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast, and mammalian cells. Molecular Endocrinology (Baltimore, Md.). 6: 861-9. PMID 1495491 DOI: 10.1210/Mend.6.6.1495491 |
0.475 |
|
| 1992 |
McDonnell DP, Vegeto E, O'Malley BW. Identification of a negative regulatory function for steroid receptors Proceedings of the National Academy of Sciences of the United States of America. 89: 10563-10567. PMID 1438251 DOI: 10.1073/Pnas.89.22.10563 |
0.659 |
|
| 1992 |
Poletti A, Weigel NL, McDonnell DP, Schrader WT, O'Malley BW, Conneely OM. A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae. Gene. 114: 51-8. PMID 1316867 DOI: 10.1016/0378-1119(92)90706-U |
0.6 |
|
| 1991 |
Liao J, Ozono K, Sone T, McDonnell DP, Pike JW. Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. Proceedings of the National Academy of Sciences of the United States of America. 87: 9751-5. PMID 2175914 DOI: 10.1073/Pnas.87.24.9751 |
0.373 |
|
| 1991 |
Pham TA, Elliston JF, Nawaz Z, Mcdonnell DP, Tsai MJ, O'Malley BW. Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers Proceedings of the National Academy of Sciences of the United States of America. 88: 3125-3129. PMID 2014231 DOI: 10.1073/Pnas.88.8.3125 |
0.617 |
|
| 1991 |
McDonnell DP, Nawaz Z, Densmore C, Weigel NL, Pham TA, Clark JH, O'Malley BW. High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae Journal of Steroid Biochemistry and Molecular Biology. 39: 291-297. PMID 1911419 DOI: 10.1016/0960-0760(91)90038-7 |
0.627 |
|
| 1991 |
McDonnell DP, Nawaz Z, O'Malley BW. In situ distinction between steroid receptor binding and transactivation at a target gene Molecular and Cellular Biology. 11: 4350-4355. PMID 1875926 DOI: 10.1128/Mcb.11.9.4350 |
0.64 |
|
| 1990 |
Hughes M, Malloy P, Kieback D, McDonnell D, Feldman D, Pike JW, O'Malley B. Human vitamin D receptor mutations: identification of molecular defects in hypocalcemic vitamin D resistant rickets. Advances in Experimental Medicine and Biology. 255: 491-503. PMID 2618873 DOI: 10.1007/978-1-4684-5679-0_52 |
0.42 |
|
| 1989 |
McDonnell DP, Pike JW, Drutz DJ, Butt TR, O'Malley BW. Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. Molecular and Cellular Biology. 9: 3517-23. PMID 2552296 DOI: 10.1128/mcb.9.8.3517-3523.1989 |
0.498 |
|
| 1989 |
McDonnell DP, Scott RA, Kerner SA, O'Malley BW, Pike JW. Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. Molecular Endocrinology (Baltimore, Md.). 3: 635-44. PMID 2542779 DOI: 10.1210/Mend-3-4-635 |
0.556 |
|
| 1988 |
Haussler MR, Mangelsdorf DJ, Komm BS, Terpening CM, Yamaoka K, Allegretto EA, Baker AR, Shine J, McDonnell DP, Hughes M. Molecular biology of the vitamin D hormone. Recent Progress in Hormone Research. 44: 263-305. PMID 2851156 DOI: 10.1016/B978-0-12-571144-9.50013-2 |
0.323 |
|
| 1988 |
McDonnell DP, Pike JW, O'Malley BW. The vitamin D receptor: a primitive steroid receptor related to thyroid hormone receptor. Journal of Steroid Biochemistry. 30: 41-6. PMID 2838696 DOI: 10.1016/0022-4731(88)90074-X |
0.563 |
|
| 1988 |
Baker AR, McDonnell DP, Hughes M, Crisp TM, Mangelsdorf DJ, Haussler MR, Pike JW, Shine J, O'Malley BW. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 3294-8. PMID 2835767 DOI: 10.1073/Pnas.85.10.3294 |
0.518 |
|
| 1987 |
McDonnell DP, Mangelsdorf DJ, Pike JW, Haussler MR, O'Malley BW. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science (New York, N.Y.). 235: 1214-7. PMID 3029866 DOI: 10.1126/Science.3029866 |
0.528 |
|
| 1987 |
Maxwell BL, McDonnell DP, Conneely OM, Schulz TZ, Greene GL, O'Malley BW. Structural organization and regulation of the chicken estrogen receptor. Molecular Endocrinology (Baltimore, Md.). 1: 25-35. PMID 2901032 DOI: 10.1210/Mend-1-1-25 |
0.532 |
|
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