Alexander W. Ensminger - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
bacterial genomics, Legionella, Legionnaires' disease, evolution

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hershkovitz D, Chen EJ, Ensminger AW, Dugan AS, Joyce AC, Segal G, Isberg RR. Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a protein that impinges on a stress response pathway. Biorxiv : the Preprint Server For Biology. PMID 38562771 DOI: 10.1101/2024.03.17.585421  0.53
2023 Lin JD, Stogios PJ, Abe KT, Wang A, MacPherson J, Skarina T, Gingras AC, Savchenko A, Ensminger AW. Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of . Mbio. 14: e0151023. PMID 37819088 DOI: 10.1128/mbio.01510-23  0.303
2018 Kaneko T, Stogios PJ, Ruan X, Voss C, Evdokimova E, Skarina T, Chung A, Liu X, Li L, Savchenko A, Ensminger AW, Li SS. Identification and characterization of a large family of superbinding bacterial SH2 domains. Nature Communications. 9: 4549. PMID 30382091 DOI: 10.2210/Pdb6E8K/Pdb  0.334
2018 Valleau D, Quaile AT, Cui H, Xu X, Evdokimova E, Chang C, Cuff ME, Urbanus ML, Houliston S, Arrowsmith CH, Ensminger AW, Savchenko A. Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila. Cell Reports. 23: 568-583. PMID 29642013 DOI: 10.1016/J.Celrep.2018.03.060  0.498
2018 Quaile AT, Stogios PJ, Egorova O, Evdokimova E, Valleau D, Nocek B, Kompella PS, Peisajovich S, Yakunin AF, Ensminger AW, Savchenko A. The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways. The Journal of Biological Chemistry. PMID 29301934 DOI: 10.1074/Jbc.M117.812727  0.498
2017 Boamah DK, Zhou G, Ensminger AW, O'Connor TJ. From Many Hosts, One Accidental Pathogen: The Diverse Protozoan Hosts of Legionella. Frontiers in Cellular and Infection Microbiology. 7: 477. PMID 29250488 DOI: 10.3389/Fcimb.2017.00477  0.425
2017 Rao C, Chin D, Ensminger AW. Priming In A Permissive Type I-C CRISPR-Cas System Reveals Distinct Dynamics Of Spacer Acquisition And Loss. Rna (New York, N.Y.). PMID 28724535 DOI: 10.1261/Rna.062083.117  0.31
2016 Urbanus ML, Quaile AT, Stogios PJ, Morar M, Rao C, Di Leo R, Evdokimova E, Lam M, Oatway C, Cuff ME, Osipiuk J, Michalska K, Nocek BP, Taipale M, Savchenko A, ... Ensminger AW, et al. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Molecular Systems Biology. 12: 893. PMID 27986836 DOI: 10.15252/Msb.20167381  0.506
2016 Rao C, Guyard C, Pelaz C, Wasserscheid J, Bondy-Denomy J, Dewar K, Ensminger AW. Active and Adaptive Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen. Cellular Microbiology. PMID 26936325 DOI: 10.1111/Cmi.12586  0.362
2015 Ensminger AW. Legionella pneumophila, armed to the hilt: justifying the largest arsenal of effectors in the bacterial world. Current Opinion in Microbiology. 29: 74-80. PMID 26709975 DOI: 10.1016/J.Mib.2015.11.002  0.466
2015 Morar M, Evdokimova E, Chang C, Ensminger AW, Savchenko A. Crystal structure of the Legionella pneumophila lem10 effector reveals a new member of the HD protein superfamily. Proteins. PMID 26426142 DOI: 10.1002/Prot.24933  0.417
2015 Quaile AT, Urbanus ML, Stogios PJ, Nocek B, Skarina T, Ensminger AW, Savchenko A. Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure (London, England : 1993). 23: 1459-69. PMID 26146184 DOI: 10.1016/J.Str.2015.05.020  0.377
2014 Ali SS, Soo J, Rao C, Leung AS, Ngai DH, Ensminger AW, Navarre WW. Silencing by H-NS potentiated the evolution of Salmonella. Plos Pathogens. 10: e1004500. PMID 25375226 DOI: 10.1371/Journal.Ppat.1004500  0.348
2014 Abdel-Nour M, Duncan C, Prashar A, Rao C, Ginevra C, Jarraud S, Low DE, Ensminger AW, Terebiznik MR, Guyard C. The Legionella pneumophila collagen-like protein mediates sedimentation, autoaggregation, and pathogen-phagocyte interactions. Applied and Environmental Microbiology. 80: 1441-54. PMID 24334670 DOI: 10.1128/Aem.03254-13  0.455
2013 Khan MA, Knox N, Prashar A, Alexander D, Abdel-Nour M, Duncan C, Tang P, Amatullah H, Dos Santos CC, Tijet N, Low DE, Pourcel C, Van Domselaar G, Terebiznik M, Ensminger AW, et al. Comparative Genomics Reveal That Host-Innate Immune Responses Influence the Clinical Prevalence of Legionella pneumophila Serogroups. Plos One. 8: e67298. PMID 23826259 DOI: 10.1371/Journal.Pone.0067298  0.375
2013 Rao C, Benhabib H, Ensminger AW. Phylogenetic reconstruction of the Legionella pneumophila Philadelphia-1 laboratory strains through comparative genomics. Plos One. 8: e64129. PMID 23717549 DOI: 10.1371/Journal.Pone.0064129  0.329
2012 Ensminger AW, Yassin Y, Miron A, Isberg RR. Experimental evolution of Legionella pneumophila in mouse macrophages leads to strains with altered determinants of environmental survival. Plos Pathogens. 8: e1002731. PMID 22693450 DOI: 10.1371/Journal.Ppat.1002731  0.575
2010 Ensminger AW, Isberg RR. E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates. Infection and Immunity. 78: 3905-19. PMID 20547746 DOI: 10.1128/Iai.00344-10  0.578
2009 Ensminger AW, Isberg RR. Legionella pneumophila Dot/Icm translocated substrates: a sum of parts. Current Opinion in Microbiology. 12: 67-73. PMID 19157961 DOI: 10.1016/J.Mib.2008.12.004  0.562
2004 Ensminger AW, Chess A. Coordinated replication timing of monoallelically expressed genes along human autosomes. Human Molecular Genetics. 13: 651-8. PMID 14734625 DOI: 10.1093/Hmg/Ddh062  0.301
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