Byron W. Kemper - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Neuroscience Biology, Cell Biology

71/155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Byun S, Seok S, Kim YC, Zhang Y, Yau P, Iwamori N, Xu HE, Ma J, Kemper B, Kemper JK. Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase. Nature Communications. 11: 807. PMID 32042044 DOI: 10.1038/S41467-020-14384-Z  0.655
2019 Byun S, Jung H, Chen J, Kim YC, Kim DH, Kong B, Guo G, Kemper B, Kemper JK. Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis. The Journal of Biological Chemistry. PMID 30996006 DOI: 10.1074/Jbc.Ra119.008360  0.389
2018 Kim YC, Byun S, Seok S, Guo G, Xu HE, Kemper B, Kemper JK. Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption. Gastroenterology. PMID 30521806 DOI: 10.1053/J.Gastro.2018.11.061  0.327
2018 Byun S, Kim DH, Ryerson D, Kim YC, Sun H, Kong B, Yau P, Guo G, Xu HE, Kemper B, Kemper JK. Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis. Nature Communications. 9: 2590. PMID 29968724 DOI: 10.1038/S41467-018-04697-5  0.675
2018 Seok S, Kim YC, Byun S, Choi S, Xiao Z, Iwamori N, Zhang Y, Wang C, Ma J, Ge K, Kemper B, Kemper JK. Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation. The Journal of Clinical Investigation. PMID 29911994 DOI: 10.1172/Jci97736  0.348
2018 Kim YC, Seok S, Byun S, Kong B, Zhang Y, Guo G, Xie W, Ma J, Kemper B, Kemper JK. AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Nature Communications. 9: 540. PMID 29416063 DOI: 10.1038/S41467-018-03060-Y  0.319
2017 Kwon S, Seok S, Yau P, Li X, Kemper B, Kemper JK. Obesity and aging diminish SIRT1-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3. The Journal of Biological Chemistry. PMID 28808064 DOI: 10.1074/Jbc.M117.778720  0.62
2017 Choi SE, Kwon S, Seok S, Xiao Z, Lee KW, Kang Y, Li X, Shinoda K, Kajimura S, Kemper B, Kemper JK. Obesity-linked phosphorylation of SIRT1 by CK2 inhibits its nuclear localization and promotes fatty liver. Molecular and Cellular Biology. PMID 28533219 DOI: 10.1128/Mcb.00006-17  0.31
2017 Byun S, Kim YC, Zhang Y, Kong B, Guo G, Sadoshima J, Ma J, Kemper B, Kemper JK. A postprandial FGF19-SHP-LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy. The Embo Journal. PMID 28446510 DOI: 10.15252/Embj.201695500  0.377
2016 Kim DH, Kwon S, Byun S, Xiao Z, Park S, Wu SY, Chiang CM, Kemper B, Kemper JK. Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis. Nature Communications. 7: 12179. PMID 27412403 DOI: 10.1038/Ncomms12179  0.425
2015 Kim YC, Byun S, Zhang Y, Seok S, Kemper B, Ma J, Kemper JK. Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2. Genome Biology. 16: 268. PMID 26634251 DOI: 10.1186/S13059-015-0835-6  0.482
2015 Fu T, Kim YC, Byun S, Kim DH, Seok S, Suino-Powell K, Xu HE, Kemper B, Kemper JK. FXR primes the liver for intestinal FGF15 signaling by transient induction of βKlotho. Molecular Endocrinology (Baltimore, Md.). me20151226. PMID 26505219 DOI: 10.1210/Me.2015-1226  0.41
2015 Kim YC, Fang S, Byun S, Seok S, Kemper B, Kemper JK. Farnesoid X receptor-induced lysine-specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity. Hepatology (Baltimore, Md.). 62: 220-31. PMID 25545350 DOI: 10.1002/Hep.27677  0.42
2014 Seok S, Fu T, Choi SE, Li Y, Zhu R, Kumar S, Sun X, Yoon G, Kang Y, Zhong W, Ma J, Kemper B, Kemper JK. Transcriptional regulation of autophagy by an FXR-CREB axis. Nature. 516: 108-11. PMID 25383523 DOI: 10.1038/Nature13949  0.301
2011 Li B, Yau P, Kemper B.. Identification of cytochrome P450 2C2 protein complexes in mouse liver. Proteomics. 16: 3359. PMID 21751364 DOI: 10.1002/Pmic.201100001  0.644
2011 Szczesna-Skorupa E, Kemper B. Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductase. Molecular Pharmacology. 79: 340-350. PMID 21081644 DOI: 10.1124/Mol.110.068478  0.373
2008 Szczesna-Skorupa E, Kemper B. Proteasome inhibition compromises direct retention of cytochrome P450 2C2 in the endoplasmic reticulum. Experimental Cell Research. 314: 3221-3231. PMID 18755184 DOI: 10.1016/J.Yexcr.2008.08.003  0.354
2008 Szczesna-Skorupa E, Kemper B. Influence of protein-protein interactions on the cellular localization of cytochrome P450. Expert Opinion On Drug Metabolism & Toxicology. 4: 123-136. PMID 18248308 DOI: 10.1517/17425255.4.2.123  0.307
2007 Xia J, Liao L, Sarkar J, Matsumoto K, Reddy JK, Xu J, Kemper B. Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members. Archives of Biochemistry and Biophysics. 468: 49-57. PMID 17950690 DOI: 10.1016/J.Abb.2007.09.005  0.38
2007 Xia J, Kemper B. Subcellular trafficking signals of constitutive androstane receptor: evidence for a nuclear export signal in the DNA-binding domain. Drug Metabolism and Disposition. 35: 1489-1494. PMID 17567731 DOI: 10.1124/Dmd.107.016493  0.454
2006 Zhang Q, Bae Y, Kemper JK, Kemper B. Analysis of multiple nuclear receptor binding sites for CAR/RXR in the phenobarbital responsive unit of CYP2B2. Archives of Biochemistry and Biophysics. 451: 119-27. PMID 16725103 DOI: 10.1016/J.Abb.2006.04.016  0.745
2006 Ozalp C, Szczesna-Skorupa E, Kemper B. Identification of membrane-contacting loops of the catalytic domain of cytochrome P450 2C2 by tryptophan fluorescence scanning. Biochemistry. 45: 4629-4637. PMID 16584198 DOI: 10.1021/Bi051372T  0.304
2006 Szczesna-Skorupa E, Kemper B. BAP31 is involved in the retention of cytochrome P450 2C2 in the endoplasmic reticulum. Journal of Biological Chemistry. 281: 4142-4148. PMID 16332681 DOI: 10.1074/Jbc.M509522200  0.343
2005 Jia Y, Guo GL, Surapureddi S, Sarkar J, Qi C, Guo D, Xia J, Kashireddi P, Yu S, Cho YW, Rao MS, Kemper B, Ge K, Gonzalez FJ, Reddy JK. Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 102: 12531-6. PMID 16109766 DOI: 10.1073/Pnas.0506000102  0.462
2005 Ozalp C, Szczesna-Skorupa E, Kemper B. Bimolecular fluorescence complementation analysis of cytochrome p450 2c2, 2e1, and NADPH-cytochrome p450 reductase molecular interactions in living cells. Drug Metabolism and Disposition. 33: 1382-1390. PMID 15980100 DOI: 10.1124/Dmd.105.005538  0.317
2005 Xia J, Kemper B. Structural determinants of constitutive androstane receptor required for its glucocorticoid receptor interacting protein-1-mediated nuclear accumulation Journal of Biological Chemistry. 280: 7285-7293. PMID 15591315 DOI: 10.1074/Jbc.M409696200  0.476
2004 Kemper B. Structural basis for the role in protein folding of conserved proline-rich regions in cytochromes P450 Toxicology and Applied Pharmacology. 199: 305-315. PMID 15364546 DOI: 10.1016/J.Taap.2003.11.030  0.37
2004 Bae Y, Kemper JK, Kemper B. Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP). Dna and Cell Biology. 23: 81-91. PMID 15000748 DOI: 10.1089/104454904322759894  0.745
2004 Szczesna-Skorupa E, Chen CD, Liu H, Kemper B. Gene Expression Changes Associated with the Endoplasmic Reticulum Stress Response Induced by Microsomal Cytochrome P450 Overproduction Journal of Biological Chemistry. 279: 13953-13961. PMID 14718536 DOI: 10.1074/Jbc.M312170200  0.396
2003 Szczesna-Skorupa E, Mallah B, Kemper B. Fluorescence resonance energy transfer analysis of cytochromes P450 2C2 and 2E1 molecular interactions in living cells. Journal of Biological Chemistry. 278: 31269-31276. PMID 12766165 DOI: 10.1074/Jbc.M301489200  0.325
2003 Rivera-Rivera I, Kim J, Kemper B. Transcriptional analysis in vivo of the hepatic genes, Cyp2b9 and Cyp2b10, by intravenous administration of plasmid DNA in mice. Biochimica Et Biophysica Acta. 1619: 254-62. PMID 12573485 DOI: 10.1016/S0304-4165(02)00484-1  0.746
2002 Min G, Kemper JK, Kemper B. Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo. The Journal of Biological Chemistry. 277: 26356-63. PMID 12000748 DOI: 10.1074/Jbc.M200051200  0.465
2001 Szczesna-Skorupa E, Kemper B. The Juxtamembrane Sequence of Cytochrome P-450 2C1 Contains an Endoplasmic Reticulum Retention Signal Journal of Biological Chemistry. 276: 45009-45014. PMID 11557755 DOI: 10.1074/Jbc.M104676200  0.364
2001 Doray B, Chen CD, Kemper B. N-terminal deletions and His-tag fusions dramatically affect expression of cytochrome p450 2C2 in bacteria. Archives of Biochemistry and Biophysics. 393: 143-153. PMID 11516171 DOI: 10.1006/Abbi.2001.2473  0.361
2001 Liu S, Rivera-Rivera I, Bredemeyer AJ, Kemper B. Functional analysis of the phenobarbital-responsive unit in rat CYP2B2 Biochemical Pharmacology. 62: 21-28. PMID 11377393 DOI: 10.1016/S0006-2952(01)00635-9  0.737
2001 Kim J, Min G, Kemper B. Chromatin assembly enhances binding to the CYP2B1 phenobarbital-responsive unit (PBRU) of nuclear factor-1, which binds simultaneously with constitutive androstane receptor (CAR)/retinoid X receptor (RXR) and enhances CAR/RXR-mediated activation of the PBRU. The Journal of Biological Chemistry. 276: 7559-67. PMID 11113125 DOI: 10.1074/Jbc.M008090200  0.459
2000 Szczesna-Skorupa E, Kemper BW. Endoplasmic reticulum retention determinants in the transmembrane and linker domains of cytochrome P450 2C1. Journal of Biological Chemistry. 275: 19409-19415. PMID 10781599 DOI: 10.1074/Jbc.M002394200  0.374
2000 Kim J, Rivera-Rivera I, Kemper B. Tissue-specific chromatin structure of the phenobarbital-responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital. Nucleic Acids Research. 28: 1126-32. PMID 10666453 DOI: 10.1093/Nar/28.5.1126  0.732
2000 Szczesna-Skorupa E, Chen CD, Kemper B. Cytochromes P450 2C1/2 and P450 2E1 are retained in the endoplasmic reticulum membrane by different mechanisms. Archives of Biochemistry and Biophysics. 374: 128-136. PMID 10666290 DOI: 10.1006/Abbi.1999.1628  0.344
1999 Doray B, Chen CD, Kemper B. Substitutions in the C-terminal portion of the catalytic domain partially reverse assembly defects introduced by mutations in the N-terminal linker sequence of cytochrome P450 2C2. Biochemistry. 38: 12180-12186. PMID 10508423 DOI: 10.1021/Bi9906266  0.358
1998 Szczesna-Skorupa E, Chen CIDI, Rogers S, Kemper B. Mobility of cytochrome P450 in the endoplasmic reticulum membrane Proceedings of the National Academy of Sciences of the United States of America. 95: 14793-14798. PMID 9843968 DOI: 10.1073/Pnas.95.25.14793  0.349
1998 Chen CD, Doray B, Kemper B. A conserved proline-rich sequence between the N-terminal signal-anchor and catalytic domains is required for assembly of functional cytochrome P450 2C2. Archives of Biochemistry and Biophysics. 350: 233-238. PMID 9473296 DOI: 10.1006/Abbi.1997.0524  0.381
1998 Kemper B. Regulation of Cytochrome P450 Gene Transcription by Phenobarbital Progress in Nucleic Acid Research and Molecular Biology. 61: 25-64. DOI: 10.1016/S0079-6603(08)60824-7  0.499
1997 Kim J, Kemper B. Phenobarbital alters protein binding to the CYP2B1/2 phenobarbital-responsive unit in native chromatin. The Journal of Biological Chemistry. 272: 29423-5. PMID 9367997 DOI: 10.1074/Jbc.272.47.29423  0.484
1996 Chen CD, Kemper B. Different Structural Requirements at Specific Proline Residue Positions in the Conserved Proline-rich Region of Cytochrome P450 2C2 Journal of Biological Chemistry. 271: 28607-28611. PMID 8910491 DOI: 10.1074/Jbc.271.45.28607  0.374
1996 Li H, Liu S, Kemper B. Sex- and tissue-specific expression of a cytochrome P450 2C2-luciferase transgene Molecular and Cellular Endocrinology. 120: 77-83. PMID 8809741 DOI: 10.1016/0303-7207(96)03823-3  0.377
1996 Park Y, Li H, Kemper B. Phenobarbital Induction Mediated by a Distal CYP2B2 Sequence in Rat Liver Transiently Transfected in Situ Journal of Biological Chemistry. 271: 23725-23728. PMID 8798596 DOI: 10.1074/Jbc.271.39.23725  0.468
1995 Ramarao MK, Straub P, Kemper B. Identification by in Vitro Mutagenesis of the Interaction of Two Segments of C2MstC1, a Chimera of Cytochromes P450 2C2 and P450 2C1 Journal of Biological Chemistry. 270: 1873-1880. PMID 7829524 DOI: 10.1074/Jbc.270.4.1873  0.347
1995 Chen D, Park Y, Kemper B. Differential protein binding and transcriptional activities of HNF-4 elements in three closely related CYP2C genes. Dna and Cell Biology. 13: 771-9. PMID 7772258 DOI: 10.1089/Dna.1994.13.771  0.473
1995 Szczesna-Skorupa E, Ahn K, Chen C, Doray B, Kemper B. The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum Journal of Biological Chemistry. 270: 24327-24333. PMID 7592644 DOI: 10.1074/Jbc.270.41.24327  0.353
1994 Straub P, Lloyd M, Johnson EF, Kemper B. Differential effects of mutations in substrate recognition site 1 of cytochrome P450 2C2 on lauric acid and progesterone hydroxylation. Biochemistry. 33: 8029-34. PMID 8025107 DOI: 10.1021/Bi00192A006  0.354
1994 Ahn K, Chen D, Kemper B. Inverse relationship of cotranslational translocation with the hydrophobic moment of the bovine preproparathyroid hormone signal sequence Biochimica Et Biophysica Acta. 1224: 459-462. PMID 7803504 DOI: 10.1016/0167-4889(94)90283-6  0.356
1993 Richardson TH, Hsu MH, Kronbach T, Barnes HJ, Chan G, Waterman MR, Kemper B, Johnson EF. Purification and characterization of recombinant-expressed cytochrome P450 2C3 from Escherichia coli: 2C3 encodes the 6β-hydroxylase deficient form of P450 3b Archives of Biochemistry and Biophysics. 300: 510-516. PMID 8380971 DOI: 10.1006/Abbi.1993.1069  0.312
1993 Szczesna-Skorupa E, Straub P, Kemper B. Deletion of a Conserved Tetrapeptide, PPGP, in P450 2C2 Results in Loss of Enzymatic Activity without a Change in Its Cellular Location Archives of Biochemistry and Biophysics. 304: 170-175. PMID 8323283 DOI: 10.1006/Abbi.1993.1335  0.396
1993 Straub P, Ramarao MK, Kemper B. Preference for aromatic substitutions at tryptophan-120, which is highly conserved and a potential mediator of electron transfer in cytochrome P450 2C2. Biochemical and Biophysical Research Communications. 197: 433-439. PMID 8267578 DOI: 10.1006/Bbrc.1993.2498  0.305
1993 Straub P, Johnson EF, Kemper B. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. Archives of Biochemistry and Biophysics. 306: 521-7. PMID 8215458 DOI: 10.1006/Abbi.1993.1547  0.319
1991 Kronbach T, Kemper B, Johnson EF. A hypervariable region of P450IIC5 confers progesterone 21-hydroxylase activity to P450IIC1. Biochemistry. 30: 6097-102. PMID 2059619 DOI: 10.1021/Bi00239A003  0.373
1991 Szczesna-Skorupa E, Kemper B. Cell-free analysis of targeting of cytochrome P450 to microsomal membranes. Methods in Enzymology. 206: 64-75. PMID 1784247 DOI: 10.1016/0076-6879(91)06077-G  0.329
1991 Kim JS, Kemper B. Differences in deoxyribonuclease I hypersensitive sites in phenobarbital-inducible and constitutive rabbit P450IIC genes. Biochemistry. 30: 10287-94. PMID 1718415 DOI: 10.1021/Bi00106A029  0.455
1989 Szczesna-Skorupa E, Kemper B. N-terminal basic amino acids are not required for translocation and processing of preproparathyroid hormone. Molecular Endocrinology. 3: 174-178. PMID 2563567 DOI: 10.1210/Mend-3-1-174  0.315
1987 Zhao J, Leighton JK, Kemper B. Characterization of rabbit cytochrome P450IIC4 cDNA and induction by phenobarbital of related hepatic mRNA levels Biochemical and Biophysical Research Communications. 146: 224-231. PMID 3453118 DOI: 10.1016/0006-291X(87)90714-5  0.386
1986 Szczesna-Skorupa E, Mead DA, Kemper B. The selection of the first AUG as the initiator of eucaryotic mRNAs translation is favored by a 5'-terminal cap group and a purine in the -3' position. Biochemical and Biophysical Research Communications. 140: 288-293. PMID 3778450 DOI: 10.1016/0006-291X(86)91088-0  0.332
1986 Kemper B. Molecular biology of parathyroid hormone. Critical Reviews in Biochemistry and Molecular Biology. 19: 353-379. PMID 3516570 DOI: 10.3109/10409238609082545  0.401
1986 Mead DA, Szczesna-Skorupa E, Kemper B. Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering. Protein Engineering. 1: 67-74. PMID 3507689 DOI: 10.1093/Protein/1.1.67  0.372
1985 Mead DA, Skorupa ES, Kemper B. Single stranded DNA SP6 promoter plasmids for engineering mutant RNAs and proteins: synthesis of a 'stretched' preproparathyroid hormone. Nucleic Acids Research. 13: 1103-1118. PMID 3858795 DOI: 10.1093/Nar/13.4.1103  0.308
1984 Leighton JK, DeBrunner-Vossbrinck BA, Kemper B. Isolation and sequence analysis of three cloned cDNAs for rabbit liver proteins that are related to rabbit cytochrome P-450 (form 2), the major phenobarbital-inducible form. Biochemistry. 23: 204-210. PMID 6546520 DOI: 10.1021/Bi00297A005  0.404
1984 Weaver CA, Gordon DF, Kissil MS, Mead DA, Kemper B. Isolation and complete nucleotide sequence of the gene for bovine parathyroid hormone. Gene. 28: 319-29. PMID 6086460 DOI: 10.1016/0378-1119(84)90149-5  0.384
1982 Weaver CA, Gordon DF, Kemper B. Nucleotide sequence of bovine parathyroid hormone messenger RNA. Molecular and Cellular Endocrinology. 28: 411-24. PMID 6185374 DOI: 10.1016/0303-7207(82)90136-8  0.347
1981 Weaver CA, Gordon DF, Kemper B. Introduction by molecular cloning of artifactual inverted sequences at the 5' terminus of the sense strand of bovine parathyroid hormone cDNA. Proceedings of the National Academy of Sciences of the United States of America. 78: 4073-7. PMID 6170060 DOI: 10.1073/Pnas.78.7.4073  0.352
1980 Gordon DF, Kemper B. Synthesis, restriction analysis, and molecular cloning of near full length DNA complementary to bovine parathyroid hormone mRNA Nucleic Acids Research. 8: 5669-5683. PMID 6258149 DOI: 10.1093/Nar/8.23.5669  0.307
1978 Habener JF, Rosenblatt M, Kemper B, Kronenberg HM, Rich A, Potts JT. Pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region. Proceedings of the National Academy of Sciences of the United States of America. 75: 2616-20. PMID 96437 DOI: 10.1073/Pnas.75.6.2616  0.326
Low-probability matches (unlikely to be authored by this person)
2019 Kim YC, Jung H, Seok S, Zhang Y, Ma J, Li T, Kemper B, Kemper JK. MicroRNA-210 promotes bile acid-induced cholestatic liver injury by targeting mixed-lineage leukemia-4 methyltransferase in mice. Hepatology (Baltimore, Md.). PMID 31549733 DOI: 10.1002/Hep.30966  0.3
1995 Richardson TH, Jung F, Griffin KJ, Wester M, Raucy JL, Kemper B, Bornheim LM, Hassett C, Omiecinski CJ, Johnson EF. A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli Archives of Biochemistry and Biophysics. 323: 87-96. PMID 7487078 DOI: 10.1006/Abbi.1995.0013  0.296
1976 Kemper B. Inactivation of parathyroid hormone mRNA by treatment with periodate and aniline. Nature. 262: 321-323. PMID 183127 DOI: 10.1038/262321A0  0.294
1988 Szczesna-Skorupa E, Browne N, Mead D, Kemper B. Positive charges at the NH2 terminus convert the membrane-anchor signal peptide of cytochrome P-450 to a secretory signal peptide Proceedings of the National Academy of Sciences of the United States of America. 85: 738-742. PMID 3422456 DOI: 10.1073/Pnas.85.3.738  0.291
2020 Kim YC, Seok S, Zhang Y, Ma J, Kong B, Guo G, Kemper B, Kemper JK. Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A. Nature Communications. 11: 5969. PMID 33235221 DOI: 10.1038/s41467-020-19803-9  0.287
1972 Kemper B, Habener JF, Potts JT, Rich A. Proparathyroid hormone: identification of a biosynthetic precursor to parathyroid hormone Proceedings of the National Academy of Sciences of the United States of America. 69: 643-647. PMID 4501579 DOI: 10.1073/Pnas.69.3.643  0.279
1998 Skorupa E, Kemper B. Signals for retention of cytochrome P450 in the endoplasmic reticulum. Methods of Molecular Biology. 107: 251-266. PMID 14577235 DOI: 10.1385/0-89603-519-0:251  0.276
1988 Mead DA, Kemper B. Chimeric single-stranded DNA phage-plasmid cloning vectors. Biotechnology(Faisalabad). 10: 85-102. PMID 3061525 DOI: 10.1016/B978-0-409-90042-2.50010-6  0.274
1979 Dorner AJ, Kemper B. Formation in vitro of membrane-bound polysomes containing parathyroid hormone messenger ribonucleic acid. Biochemistry. 18: 5496-5501. PMID 518852 DOI: 10.1021/Bi00591A036  0.27
1997 Golz S, Christoph A, Birkenkamp-Demtröder K, Kemper B. Identification of amino acids of endonuclease VII essential for binding and cleavage of cruciform DNA. European Journal of Biochemistry. 245: 573-80. PMID 9182992 DOI: 10.1111/j.1432-1033.1997.00573.x  0.269
2023 Chen J, Wang R, Xiong F, Sun H, Kemper B, Li W, Kemper JK. Hammerhead-type FXR agonists induce an eRNA FincoR that ameliorates nonalcoholic steatohepatitis in mice. Biorxiv : the Preprint Server For Biology. PMID 38045226 DOI: 10.1101/2023.11.20.567833  0.264
1998 Birkenbihl RP, Kemper B. Endonuclease VII has two DNA-binding sites each composed from one N- and one C-terminus provided by different subunits of the protein dimer. The Embo Journal. 17: 4527-34. PMID 9687518 DOI: 10.1093/emboj/17.15.4527  0.264
2020 Jung H, Chen J, Hu X, Sun H, Wu SY, Chiang CM, Kemper B, Chen LF, Kemper J. BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination. Jci Insight. PMID 33290278 DOI: 10.1172/jci.insight.141640  0.263
1989 Kemper B, Szczesna-Skorupa E. Cytochrome P-450 membrane signals. Drug Metabolism Reviews. 20: 811-820. PMID 2680408 DOI: 10.3109/03602538909103580  0.263
2015 Kim DH, Xiao Z, Kwon S, Sun X, Ryerson D, Tkac D, Ma P, Wu SY, Chiang CM, Zhou E, Xu HE, Palvimo JJ, Chen LF, Kemper B, Kemper JK. A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity. The Embo Journal. 34: 184-99. PMID 25425577 DOI: 10.15252/Embj.201489527  0.26
2014 Fu T, Seok S, Choi S, Huang Z, Suino-Powell K, Xu HE, Kemper B, Kemper JK. MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function. Molecular and Cellular Biology. 34: 4130-42. PMID 25182532 DOI: 10.1128/Mcb.00596-14  0.257
2001 Hartung M, Slack M, Kemper B. Analyses of spontaneous mutations of cloned gene 49 of phage T4. Mutation Research. 473: 201-10. PMID 11166037 DOI: 10.1016/S0027-5107(00)00150-0  0.247
2022 Seok S, Kim YC, Zhang Y, Kong B, Guo G, Ma J, Kemper B, Kemper JK. Feeding activates FGF15-SHP-TFEB-mediated lipophagy in the gut. The Embo Journal. e109997. PMID 35686465 DOI: 10.15252/embj.2021109997  0.243
2002 Rass U, Kemper B. Crp1p, a new cruciform DNA-binding protein in the yeast Saccharomyces cerevisiae. Journal of Molecular Biology. 323: 685-700. PMID 12419258 DOI: 10.1016/S0022-2836(02)00993-2  0.241
1992 Kleff S, Kemper B, Sternglanz R. Identification and characterization of yeast mutants and the gene for a cruciform cutting endonuclease Embo Journal. 11: 699-704. PMID 1537343 DOI: 10.1002/J.1460-2075.1992.Tb05102.X  0.237
1977 Kemper B, Stolarsky L. Dependence on potassium concentration of the inhibition of the translation of messenger ribonucleic acid by 7-methylguanosine 5'-phosphate. Biochemistry. 16: 5676-5680. PMID 201273 DOI: 10.1021/Bi00645A004  0.236
2023 Kim YC, Qi M, Dong X, Seok S, Sun H, Kemper B, Fu T, Kemper JK. Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease. The Journal of Biological Chemistry. 104946. PMID 37348559 DOI: 10.1016/j.jbc.2023.104946  0.227
1998 Birkenbihl RP, Kemper B. Localization and characterization of the dimerization domain of holliday structure resolving endonuclease VII of phage T4. Journal of Molecular Biology. 280: 73-83. PMID 9653032 DOI: 10.1006/JMBI.1998.1851  0.225
2001 Raaijmakers H, Törö I, Birkenbihl R, Kemper B, Suck D. Conformational flexibility in T4 endonuclease VII revealed by crystallography: implications for substrate binding and cleavage. Journal of Molecular Biology. 308: 311-23. PMID 11327769 DOI: 10.1006/JMBI.2001.4592  0.224
1978 Dorner AJ, Kemper B. Conversion of pre-proparathyroid hormone to proparathyroid hormone by dog pancreatic microsomes. Biochemistry. 17: 5550-5555. PMID 728415 DOI: 10.1021/Bi00618A034  0.217
1996 Kupfer C, Kemper B. Reactions of mitochondrial cruciform cutting endonuclease 1 (CCE1) of yeast Saccharomyces cerevisiae with branched DNAs in vitro. European Journal of Biochemistry. 238: 77-87. PMID 8665955 DOI: 10.1111/J.1432-1033.1996.0077Q.X  0.209
1997 Birkenkamp-Demtröder K, Golz S, Kemper B. Inhibition of Holliday structure resolving endonuclease VII of bacteriophage T4 by recombination enzymes UvsX and UvsY. Journal of Molecular Biology. 267: 150-62. PMID 9096214 DOI: 10.1006/JMBI.1996.0847  0.208
2010 Hu G, Johnson EF, Kemper B. CYP2C8 exists as a dimer in natural membranes Drug Metabolism and Disposition. 38: 1976-1983. PMID 20699412 DOI: 10.1124/Dmd.110.034942  0.202
1972 Habener JF, Kemper B. Pro-parathyroid hormone. Annals of Internal Medicine. 77: 151-152. PMID 5052442 DOI: 10.7326/0003-4819-77-1-151  0.201
1999 Raaijmakers H, Vix O, Törõ I, Golz S, Kemper B, Suck D. X-ray structure of T4 endonuclease VII: a DNA junction resolvase with a novel fold and unusual domain-swapped dimer architecture. The Embo Journal. 18: 1447-58. PMID 10075917 DOI: 10.1093/emboj/18.6.1447  0.2
1998 Golz S, Greger B, Kemper B. Enzymatic mutation detection. Phosphate ions increase incision efficiency of endonuclease VII at a variety of damage sites in DNA. Mutation Research. 382: 85-92. PMID 9691988 DOI: 10.1016/S1383-5726(97)00011-3  0.199
1984 Lilley DM, Kemper B. Cruciform-resolvase interactions in supercoiled DNA. Cell. 36: 413-22. PMID 6319022 DOI: 10.1016/0092-8674(84)90234-4  0.199
1996 Golz S, Birkenbihl RP, Kemper B. Improved large-scale preparation of phage T4 endonuclease VII overexpressed in E. coli. Dna Research : An International Journal For Rapid Publication of Reports On Genes and Genomes. 2: 277-84. PMID 8867802 DOI: 10.1093/DNARES/2.6.277  0.192
1998 Christoph A, v Heesberg G, Kemper B. Epitope mapping of T4 endonuclease VII with monoclonal antibodies reveals importance of both ends of the protein for target binding. Journal of Molecular Biology. 277: 529-40. PMID 9533878 DOI: 10.1006/jmbi.1998.1628  0.189
1998 Kupfer C, Lee S, Kemper B. Binding of endonuclease VII to cruciform DNA. Visualization in the electron microscope. The Journal of Biological Chemistry. 273: 31637-9. PMID 9822621 DOI: 10.1074/jbc.273.48.31637  0.186
1999 Golz S, Kemper B. Association of holliday-structure resolving endonuclease VII with gp20 from the packaging machine of phage T4. Journal of Molecular Biology. 285: 1131-44. PMID 9918721 DOI: 10.1006/JMBI.1998.2399  0.182
1990 Picksley SM, Parsons CA, Kemper B, West SC. Cleavage specificity of bacteriophage T4 endonuclease VII and bacteriophage T7 endonuclease I on synthetic branch migratable Holliday junctions. Journal of Molecular Biology. 212: 723-35. PMID 2158565 DOI: 10.1016/0022-2836(90)90233-C  0.18
1990 Kosak HG, Kemper BW. Large-scale preparation of T4 endonuclease VII from over-expressing bacteria. European Journal of Biochemistry / Febs. 194: 779-84. PMID 2269300  0.178
1992 Pottmeyer S, Kemper B. T4 endonuclease VII resolves cruciform DNA with nick and counter-nick and its activity is directed by local nucleotide sequence. Journal of Molecular Biology. 223: 607-15. PMID 1542108 DOI: 10.1016/0022-2836(92)90977-R  0.174
1972 Saedler H, Besemer J, Kemper B, Rosenwirth B, Starlinger P. Insertion mutations in the control region of the Gal operon of E. coli. I. Biological characterization of the mutations. Molecular Genetics and Genomics. 115: 258-265. PMID 4555679 DOI: 10.1007/Bf00268889  0.173
1998 Greger B, Kemper B. An apyrimidinic site kinks DNA and triggers incision by endonuclease VII of phage T4. Nucleic Acids Research. 26: 4432-8. PMID 9742246 DOI: 10.1093/nar/26.19.4432  0.172
2001 Birkenbihl RP, Neef K, Prangishvili D, Kemper B. Holliday junction resolving enzymes of archaeal viruses SIRV1 and SIRV2. Journal of Molecular Biology. 309: 1067-76. PMID 11399079 DOI: 10.1006/JMBI.2001.4761  0.168
1994 Bertrand-Burggraf E, Kemper B, Fuchs RP. Endonuclease VII of phage T4 nicks N-2-acetylaminofluorene-induced DNA structures in vitro. Mutation Research. 314: 287-95. PMID 7513060 DOI: 10.1016/0921-8777(94)90072-8  0.168
2002 Neef K, Birkenbihl RP, Kemper B. Holliday junction-resolving enzymes from eight hyperthermophilic archaea differ in reactions with cruciform DNA. Extremophiles : Life Under Extreme Conditions. 6: 359-67. PMID 12382111 DOI: 10.1007/s00792-002-0265-8  0.166
2011 Szczesna-Skorupa E, Kemper B. The signal-anchor sequence of CYP2C1 inserts into the membrane as a hairpin structure. Biochemical and Biophysical Research Communications. 415: 405-9. PMID 22040732 DOI: 10.1016/j.bbrc.2011.10.082  0.166
1974 Kemper B, Jährig L. Suppression of DNA arrest mutants in bacteriophage T4. Journal of Virology. 13: 1408-11. PMID 4598787 DOI: 10.1128/jvi.13.6.1408-1411.1974  0.165
1991 Bhattacharyya A, Murchie AI, von Kitzing E, Diekmann S, Kemper B, Lilley DM. Model for the interaction of DNA junctions and resolving enzymes. Journal of Molecular Biology. 221: 1191-207. PMID 1658336 DOI: 10.1016/0022-2836(91)90928-Y  0.164
1989 Jensch F, Kosak H, Seeman NC, Kemper B. Cruciform cutting endonucleases from Saccharomyces cerevisiae and phage T4 show conserved reactions with branched DNAs. The Embo Journal. 8: 4325-34. PMID 2556268 DOI: 10.1002/J.1460-2075.1989.Tb08619.X  0.161
1993 Flemming M, Deumling B, Kemper B. Function of gene 49 of bacteriophage T4 III. Isolation of Holliday structures from very fast-sedimenting DNA. Virology. 196: 910-3. PMID 8372457 DOI: 10.1006/VIRO.1993.1557  0.155
1976 Kemper B, Brown DT. Function of gene 49 of bacteriophage T4. II. Analysis of intracellular development and the structure of very fast sedimenting DNA Journal of Virology. 18: 1000-1015. PMID 775128 DOI: 10.1128/JVI.18.3.1000-1015.1976  0.155
2020 Seok S, Sun H, Kim YC, Kemper B, Kemper JK. Defective FXR-SHP Regulation in Obesity Aberrantly Increases Expression, Promoting Insulin Resistance and Fatty Liver. Diabetes. PMID 33328206 DOI: 10.2337/db20-0856  0.155
1976 Habener JF, Kemper BW, Rich A, Potts JT. Biosynthesis of parathyroid hormone. Recent Progress in Hormone Research. 33: 249-308. PMID 801192 DOI: 10.1016/B978-0-12-571133-3.50013-1  0.153
1976 Kemper B, Janz E. Function of gene 49 of bacteriophage T4. I. Isolation and biochemical characterization of very fast-sedimenting DNA. Journal of Virology. 18: 992-9. PMID 775132 DOI: 10.1128/JVI.18.3.992-999.1976  0.151
1998 Golz S, Birkenkamp-Demtröder K, Kemper B. Enzymatic mutation detection. Procedure for screening and mapping of mutations by immobilised endonuclease VII. Nucleic Acids Research. 26: 1132-3. PMID 9461481 DOI: 10.1093/NAR/26.4.1132  0.148
1988 Duckett DR, Murchie AI, Diekmann S, von Kitzing E, Kemper B, Lilley DM. The structure of the Holliday junction, and its resolution. Cell. 55: 79-89. PMID 3167979 DOI: 10.1016/0092-8674(88)90011-6  0.146
1982 Mizuuchi K, Kemper B, Hays J, Weisberg RA. T4 endonuclease VII cleaves holliday structures. Cell. 29: 357-65. PMID 6288255 DOI: 10.1016/0092-8674(82)90152-0  0.146
1997 Youil R, Kemper B, Cotton RG. Detection of 81 of 81 known mouse beta-globin promoter mutations with T4 endonuclease VII--the EMC method. Genomics. 32: 431-5. PMID 8838807 DOI: 10.1006/GENO.1996.0138  0.14
2002 Birkenbihl RP, Kemper B. High affinity of endonuclease VII for the Holliday structure containing one nick ensures productive resolution. Journal of Molecular Biology. 321: 21-8. PMID 12139930 DOI: 10.1016/S0022-2836(02)00594-6  0.138
1995 Birkenkamp K, Kemper B. In vitro processing of heteroduplex loops and mismatches by endonuclease VII. Dna Research : An International Journal For Rapid Publication of Reports On Genes and Genomes. 2: 9-14. PMID 7788530 DOI: 10.1093/DNARES/2.1.9  0.137
1990 Müller B, Jones C, Kemper B, West SC. Enzymatic formation and resolution of Holliday junctions in vitro. Cell. 60: 329-36. PMID 2137030 DOI: 10.1016/0092-8674(90)90747-3  0.135
2022 Sun H, Seok S, Jung H, Kemper B, Kemper JK. Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice. Molecular Metabolism. 66: 101603. PMID 36126896 DOI: 10.1016/j.molmet.2022.101603  0.127
1996 Birkenkamp K, Kemper B. Bacteriophage T4 strand transfer protein UvsX tolerates symmetric and asymmetric heterologies in short double-stranded oligonucleotides. Journal of Molecular Biology. 259: 622-31. PMID 8683569 DOI: 10.1006/JMBI.1996.0344  0.125
1991 Wang YL, Mueller JE, Kemper B, Seeman NC. Assembly and characterization of five-arm and six-arm DNA branched junctions. Biochemistry. 30: 5667-74. PMID 1645997 DOI: 10.1021/Bi00237A005  0.124
1996 Giunta C, Youil R, Venter D, Chow CW, Somers G, Lafferty A, Kemper B, Cotton RG. Rapid diagnosis of germline p53 mutation using the enzyme mismatch cleavage method. Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B. 5: 265-70. PMID 8955618 DOI: 10.1097/00019606-199612000-00007  0.123
1970 Gomez J, Kemper BW, Pratt WB, Aronow L. Effects of glucocorticoids on nucleic acid synthesis in mouse lymphoma cells growing in vitro and on nuclei isolated from these cells Biochemical Pharmacology. 19: 1471-1483. PMID 5535184 DOI: 10.1016/0006-2952(70)90063-8  0.118
1998 Yang X, Vologodskii AV, Liu B, Kemper B, Seeman NC. Torsional control of double-stranded DNA branch migration. Biopolymers. 45: 69-83. PMID 9433186 DOI: 10.1002/(Sici)1097-0282(199801)45:1<69::Aid-Bip6>3.0.Co;2-X  0.118
1994 Fu TJ, Kemper B, Seeman NC. Cleavage of double-crossover molecules by T4 endonuclease VII. Biochemistry. 33: 3896-905. PMID 8142393 DOI: 10.1021/Bi00179A015  0.115
1986 Jensch F, Kemper B. Endonuclease VII resolves Y-junctions in branched DNA in vitro. The Embo Journal. 5: 181-189. DOI: 10.1002/j.1460-2075.1986.tb04194.x  0.115
1995 Youil R, Kemper BW, Cotton RG. Screening for mutations by enzyme mismatch cleavage with T4 endonuclease VII. Proceedings of the National Academy of Sciences of the United States of America. 92: 87-91. PMID 7816853  0.115
2013 Choi SE, Fu T, Seok S, Kim DH, Yu E, Lee KW, Kang Y, Li X, Kemper B, Kemper JK. Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT. Aging Cell. 12: 1062-72. PMID 23834033 DOI: 10.1111/Acel.12135  0.113
1993 Solaro PC, Birkenkamp K, Pfeiffer P, Kemper B. Endonuclease VII of phage T4 triggers mismatch correction in vitro. Journal of Molecular Biology. 230: 868-77. PMID 8478939 DOI: 10.1006/JMBI.1993.1207  0.11
1999 Sun W, Mao C, Iwasaki H, Kemper B, Seeman NC. No braiding of Holliday junctions in positively supercoiled DNA molecules. Journal of Molecular Biology. 294: 683-99. PMID 10610789 DOI: 10.1006/Jmbi.1999.3155  0.108
1969 Kemper BW, Pratt WB, Aronow L. Nucleic acid synthesis in intact nuclei isolated from mouse fibroblasts. Characterization of the system and effects of glucocorticoids Molecular Pharmacology. 5: 507-531. PMID 5823763  0.108
1988 Mueller JE, Kemper B, Cunningham RP, Kallenbach NR, Seeman NC. T4 endonuclease VII cleaves the crossover strands of Holliday junction analogs. Proceedings of the National Academy of Sciences of the United States of America. 85: 9441-5. PMID 3200829 DOI: 10.1073/Pnas.85.24.9441  0.106
2008 Solaro P, Greger B, Kemper B. Detection and Partial Purification of a Cruciform-Resolving Activity (X-solvase) from Nuclear Extracts of Mouse B-Cells European Journal of Biochemistry. 230: 926-933. DOI: 10.1111/J.1432-1033.1995.0926G.X  0.105
1985 Kemper B, Jensch F, von Depka-Prondzynski M, Fritz HJ, Borgmeyer U, Mizuuchi K. Resolution of Holliday structures by endonuclease VII as observed in interactions with cruciform DNA. Cold Spring Harbor Symposia On Quantitative Biology. 49: 815-25. PMID 6397324 DOI: 10.1101/SQB.1984.049.01.092  0.103
1990 Lu M, Guo Q, Mueller JE, Kemper B, Studier FW, Seeman NC, Kallenbach NR. Characterization of a bimobile DNA junction. Journal of Biological Chemistry. 265: 16778-16785. DOI: 10.1016/s0021-9258(17)44828-9  0.094
1990 Parsons CA, Kemper B, West SC. Interaction of a four-way junction in DNA with T4 endonuclease VII. Journal of Biological Chemistry. 265: 9285-9289. DOI: 10.1016/s0021-9258(19)38845-3  0.091
1971 Kemper B. Increased recombinant frequencies with an amber mutation in the gal-operon of E. coli. Molecular & General Genetics : Mgg. 107: 107-13. PMID 4938065 DOI: 10.1007/BF00333626  0.081
1988 Kleff S, Kemper B. Initiation of heteroduplex-loop repair by T4-encoded endonuclease VII in vitro. The Embo Journal. 7: 1527-1535. DOI: 10.1002/j.1460-2075.1988.tb02972.x  0.077
2002 Biertuempfel C, Sauter C, Basquin J, Birkenbihl R, Kemper B, Suck D. Crystallographic analysis of the Holliday junction-cutting enzyme (Hjc) fromArchaeoglobus fulgidus Acta Crystallographica Section a Foundations of Crystallography. 58: c121-c121. DOI: 10.1107/S0108767302089857  0.059
1990 Mueller J, Newton C, Jensch F, Kemper B, Cunningham R, Kallenbach N, Seeman N. Resolution of Holliday junction analogs by T4 endonuclease VII can be directed by substrate structure. Journal of Biological Chemistry. 265: 13918-13924. DOI: 10.1016/s0021-9258(18)77436-x  0.044
2005 KEMPER B, GARABETT M, COURAGE U. Studies on T4-Head Maturation European Journal of Biochemistry. 115: 133-142. DOI: 10.1111/J.1432-1033.1981.TB06208.X  0.01
2005 KEMPER B, GARABETT M. Studies on T4-Head Maturation European Journal of Biochemistry. 115: 123-131. DOI: 10.1111/J.1432-1033.1981.TB06207.X  0.01
Hide low-probability matches.