Ian G. Macara - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Microbiology Biology, Cell Biology

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Van Bergen NJ, Ahmed SM, Collins F, Cowley M, Vetro A, Dale RC, Hock DH, de Caestecker C, Menezes M, Massey S, Ho G, Pisano T, Glover S, Gusman J, Stroud DA, ... ... Macara IG, et al. Mutations in the exocyst component EXOC2 cause severe defects in human brain development. The Journal of Experimental Medicine. 217. PMID 32639540 DOI: 10.1084/Jem.20192040  0.338
2019 Fomicheva M, Tross EM, Macara IG. Polarity proteins in oncogenesis. Current Opinion in Cell Biology. 62: 26-30. PMID 31509786 DOI: 10.1016/J.Ceb.2019.07.016  0.397
2018 Ahmed SM, Nishida-Fukuda H, Li Y, McDonald WH, Gradinaru CC, Macara IG. Exocyst dynamics during vesicle tethering and fusion. Nature Communications. 9: 5140. PMID 30510181 DOI: 10.1038/S41467-018-07467-5  0.32
2018 Andrews AM, McCartney HJ, Errington TM, D'Andrea AD, Macara IG. A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links. Nature Communications. 9: 2592. PMID 29968717 DOI: 10.1038/S41467-018-05008-8  0.339
2017 Seldin L, Macara I. Epithelial spindle orientation diversities and uncertainties: recent developments and lingering questions. F1000research. 6: 984. PMID 28713562 DOI: 10.12688/F1000Research.11370.1  0.351
2017 Ahmed SM, Macara IG. The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nature Communications. 8: 14867. PMID 28358000 DOI: 10.1038/Ncomms14867  0.412
2016 Ahmed SM, Macara IG. Mechanisms of polarity protein expression control. Current Opinion in Cell Biology. 42: 38-45. PMID 27092866 DOI: 10.1016/J.Ceb.2016.04.002  0.419
2016 Puvirajesinghe TM, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, Sebbagh M, Lopez M, Brech A, Finetti P, Charafe-Jauffret E, Chaffanet M, Castellano R, Restouin A, Marchetto S, ... ... Macara I, et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nature Communications. 7: 10318. PMID 26754771 DOI: 10.1038/Ncomms10318  0.313
2015 Iioka H, Macara IG. Detection of RNA-Protein Interactions Using Tethered RNA Affinity Capture. Methods in Molecular Biology (Clifton, N.J.). 1316: 67-73. PMID 25967053 DOI: 10.1007/978-1-4939-2730-2_6  0.328
2015 Le Guelte A, Macara IG. Plasmolipin--a new player in endocytosis and epithelial development. The Embo Journal. 34: 1147-8. PMID 25825384 DOI: 10.15252/Embj.201591448  0.423
2015 Guyer RA, Macara IG. Loss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells. The Journal of Biological Chemistry. 290: 8457-68. PMID 25657002 DOI: 10.1074/Jbc.M114.621011  0.361
2015 Richardson GM, Lannigan J, Macara IG. Does FACS perturb gene expression? Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 87: 166-75. PMID 25598345 DOI: 10.1002/Cyto.A.22608  0.335
2015 Archibald A, Mihai C, Macara IG, McCaffrey L. Oncogenic suppression of apoptosis uncovers a Rac1/JNK proliferation pathway activated by loss of Par3. Oncogene. 34: 3199-206. PMID 25109337 DOI: 10.1038/Onc.2014.242  0.377
2014 Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H. Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Nature Communications. 5: 4839. PMID 25208761 DOI: 10.1038/Ncomms5839  0.421
2014 Huo Y, Macara IG. The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance. Nature Cell Biology. 16: 529-37. PMID 24859006 DOI: 10.1038/Ncb2969  0.4
2014 Andreeva A, Lee J, Lohia M, Wu X, Macara IG, Lu X. PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity. Developmental Cell. 29: 20-33. PMID 24703874 DOI: 10.1016/J.Devcel.2014.02.008  0.763
2014 Rodriguez-Boulan E, Macara IG. Organization and execution of the epithelial polarity programme. Nature Reviews. Molecular Cell Biology. 15: 225-42. PMID 24651541 DOI: 10.1038/Nrm3775  0.397
2013 Yasuda K, Zhang H, Loiselle D, Haystead T, Macara IG, Mili S. The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules. The Journal of Cell Biology. 203: 737-46. PMID 24297750 DOI: 10.1083/Jcb.201306058  0.372
2013 Petkowski JJ, Bonsignore LA, Tooley JG, Wilkey DW, Merchant ML, Macara IG, Schaner Tooley CE. NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1. The Biochemical Journal. 456: 453-62. PMID 24090352 DOI: 10.1042/Bj20131163  0.311
2013 Errington TM, Macara IG. Depletion of the adaptor protein NCK increases UV-induced p53 phosphorylation and promotes apoptosis. Plos One. 8: e76204. PMID 24086708 DOI: 10.1371/Journal.Pone.0076204  0.37
2013 Macara IG, McCaffrey L. Cell polarity in morphogenesis and metastasis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20130012. PMID 24062582 DOI: 10.1098/Rstb.2013.0012  0.357
2013 Bailey AO, Panchenko T, Sathyan KM, Petkowski JJ, Pai PJ, Bai DL, Russell DH, Macara IG, Shabanowitz J, Hunt DF, Black BE, Foltz DR. Posttranslational modification of CENP-A influences the conformation of centromeric chromatin. Proceedings of the National Academy of Sciences of the United States of America. 110: 11827-32. PMID 23818633 DOI: 10.1073/Pnas.1300325110  0.31
2012 Lohia M, Qin Y, Macara IG. The Scribble polarity protein stabilizes E-cadherin/p120-catenin binding and blocks retrieval of E-cadherin to the Golgi. Plos One. 7: e51130. PMID 23226478 DOI: 10.1371/Journal.Pone.0051130  0.75
2012 McCaffrey LM, Montalbano J, Mihai C, Macara IG. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell. 22: 601-14. PMID 23153534 DOI: 10.1016/J.Ccr.2012.10.003  0.32
2012 McCaffrey LM, Macara IG. Signaling pathways in cell polarity. Cold Spring Harbor Perspectives in Biology. 4. PMID 22553378 DOI: 10.1101/Cshperspect.A009654  0.428
2011 Kim JY, Oh MH, Bernard LP, Macara IG, Zhang H. The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. The Journal of Biological Chemistry. 286: 37615-24. PMID 21900250 DOI: 10.1074/Jbc.M111.268029  0.335
2011 Pasic L, Eisinger-Mathason TS, Velayudhan BT, Moskaluk CA, Brenin DR, Macara IG, Lannigan DA. Sustained activation of the HER1-ERK1/2-RSK signaling pathway controls myoepithelial cell fate in human mammary tissue. Genes & Development. 25: 1641-53. PMID 21828273 DOI: 10.1101/Gad.2025611  0.341
2011 McCaffrey LM, Macara IG. Epithelial organization, cell polarity and tumorigenesis. Trends in Cell Biology. 21: 727-35. PMID 21782440 DOI: 10.1016/J.Tcb.2011.06.005  0.388
2011 Iioka H, Loiselle D, Haystead TA, Macara IG. Efficient detection of RNA-protein interactions using tethered RNAs. Nucleic Acids Research. 39: e53. PMID 21300640 DOI: 10.1093/Nar/Gkq1316  0.336
2011 McCaffrey LM, Montalbano J, Macara IG. Abstract SY07-02: Polarity proteins in morphogenesis and metastasis Cellular and Molecular Biology. 71. DOI: 10.1158/1538-7445.Am2011-Sy07-02  0.343
2010 Hao Y, Du Q, Chen X, Zheng Z, Balsbaugh JL, Maitra S, Shabanowitz J, Hunt DF, Macara IG. Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Current Biology : Cb. 20: 1809-18. PMID 20933426 DOI: 10.1016/J.Cub.2010.09.032  0.622
2010 Tooley CE, Petkowski JJ, Muratore-Schroeder TL, Balsbaugh JL, Shabanowitz J, Sabat M, Minor W, Hunt DF, Macara IG. NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature. 466: 1125-8. PMID 20668449 DOI: 10.1038/Nature09343  0.308
2010 Qin Y, Meisen WH, Hao Y, Macara IG. Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation. The Journal of Cell Biology. 189: 661-9. PMID 20479467 DOI: 10.1083/Jcb.201002097  0.614
2009 McCaffrey LM, Macara IG. Widely conserved signaling pathways in the establishment of cell polarity. Cold Spring Harbor Perspectives in Biology. 1: a001370. PMID 20066082 DOI: 10.1101/Cshperspect.A001370  0.423
2009 McCaffrey LM, Macara IG. The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis. Genes & Development. 23: 1450-60. PMID 19528321 DOI: 10.1101/Gad.1795909  0.433
2009 Mili S, Macara IG. RNA localization and polarity: from A(PC) to Z(BP). Trends in Cell Biology. 19: 156-64. PMID 19251418 DOI: 10.1016/J.Tcb.2009.02.001  0.414
2008 Macara IG, Mili S. Polarity and differential inheritance--universal attributes of life? Cell. 135: 801-12. PMID 19041746 DOI: 10.1016/J.Cell.2008.11.006  0.375
2008 Eisinger-Mathason TS, Andrade J, Groehler AL, Clark DE, Muratore-Schroeder TL, Pasic L, Smith JA, Shabanowitz J, Hunt DF, Macara IG, Lannigan DA. Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Molecular Cell. 31: 722-36. PMID 18775331 DOI: 10.1016/J.Molcel.2008.06.025  0.351
2008 Hao Y, Macara IG. Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1. The Journal of Cell Biology. 182: 827-36. PMID 18762580 DOI: 10.1083/Jcb.200803110  0.592
2008 Mili S, Moissoglu K, Macara IG. Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. Nature. 453: 115-9. PMID 18451862 DOI: 10.1038/Nature06888  0.322
2008 Zhang H, Macara IG. The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Developmental Cell. 14: 216-26. PMID 18267090 DOI: 10.1016/J.Devcel.2007.11.020  0.416
2008 Dorfman J, Macara IG. STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. Molecular Biology of the Cell. 19: 1614-26. PMID 18256292 DOI: 10.1091/Mbc.E07-05-0454  0.772
2007 Goldstein B, Macara IG. The PAR proteins: fundamental players in animal cell polarization. Developmental Cell. 13: 609-22. PMID 17981131 DOI: 10.1016/J.Devcel.2007.10.007  0.451
2007 Kremer BE, Adang LA, Macara IG. Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell. 130: 837-50. PMID 17803907 DOI: 10.1016/J.Cell.2007.06.053  0.762
2007 Sirajuddin M, Farkasovsky M, Hauer F, Kühlmann D, Macara IG, Weyand M, Stark H, Wittinghofer A. Structural insight into filament formation by mammalian septins. Nature. 449: 311-5. PMID 17637674 DOI: 10.1038/Nature06052  0.391
2007 Riddick G, Macara IG. The adapter importin-alpha provides flexible control of nuclear import at the expense of efficiency. Molecular Systems Biology. 3: 118. PMID 17551513 DOI: 10.1038/Msb4100160  0.359
2007 Chen T, Muratore TL, Schaner-Tooley CE, Shabanowitz J, Hunt DF, Macara IG. N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nature Cell Biology. 9: 596-603. PMID 17435751 DOI: 10.1038/Ncb1572  0.363
2007 Capaldo CT, Macara IG. Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. Molecular Biology of the Cell. 18: 189-200. PMID 17093058 DOI: 10.1091/Mbc.E06-05-0471  0.746
2006 Krummel MF, Macara I. Maintenance and modulation of T cell polarity. Nature Immunology. 7: 1143-9. PMID 17053799 DOI: 10.1038/Ni1404  0.38
2006 Low C, Macara IG. Structural analysis of septin 2, 6, and 7 complexes. The Journal of Biological Chemistry. 281: 30697-706. PMID 16914550 DOI: 10.1074/Jbc.M605179200  0.778
2006 Macara IG, Spang A. Closing the GAP between polarity and vesicle transport. Cell. 125: 419-21. PMID 16678084 DOI: 10.1016/J.Cell.2006.04.011  0.378
2006 Chen X, Macara IG. Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly. The Journal of Cell Biology. 172: 671-8. PMID 16505165 DOI: 10.1083/Jcb.200510061  0.424
2006 Zhang H, Macara IG. The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis. Nature Cell Biology. 8: 227-37. PMID 16474385 DOI: 10.1038/Ncb1368  0.366
2006 Chen X, Macara IG. RNA interference techniques to study epithelial cell adhesion and polarity. Methods in Enzymology. 406: 362-74. PMID 16472670 DOI: 10.1016/S0076-6879(06)06026-5  0.418
2006 McNeil E, Capaldo CT, Macara IG. Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells. Molecular Biology of the Cell. 17: 1922-32. PMID 16436508 DOI: 10.1091/Mbc.E05-07-0650  0.746
2005 Qin Y, Capaldo C, Gumbiner BM, Macara IG. The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. The Journal of Cell Biology. 171: 1061-71. PMID 16344308 DOI: 10.1083/Jcb.200506094  0.757
2005 Sans N, Wang PY, Du Q, Petralia RS, Wang YX, Nakka S, Blumer JB, Macara IG, Wenthold RJ. mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression. Nature Cell Biology. 7: 1179-90. PMID 16299499 DOI: 10.1038/Ncb1325  0.327
2005 Kremer BE, Haystead T, Macara IG. Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Molecular Biology of the Cell. 16: 4648-59. PMID 16093351 DOI: 10.1091/Mbc.E05-03-0267  0.75
2005 De S, Macara IG, Lannigan DA. Novel biosensors for the detection of estrogen receptor ligands. The Journal of Steroid Biochemistry and Molecular Biology. 96: 235-44. PMID 15985367 DOI: 10.1016/J.Jsbmb.2005.04.030  0.3
2005 Riddick G, Macara IG. A systems analysis of importin-{alpha}-{beta} mediated nuclear protein import. The Journal of Cell Biology. 168: 1027-38. PMID 15795315 DOI: 10.1083/Jcb.200409024  0.77
2005 Chen X, Macara IG. Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nature Cell Biology. 7: 262-9. PMID 15723052 DOI: 10.1038/Ncb1226  0.51
2004 Kisurina-Evgenieva O, Mack G, Du Q, Macara I, Khodjakov A, Compton DA. Multiple mechanisms regulate NuMA dynamics at spindle poles. Journal of Cell Science. 117: 6391-400. PMID 15561764 DOI: 10.1242/Jcs.01568  0.418
2004 Plafker SM, Plafker KS, Weissman AM, Macara IG. Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import. The Journal of Cell Biology. 167: 649-59. PMID 15545318 DOI: 10.1083/Jcb.200406001  0.329
2004 Du Q, Macara IG. Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell. 119: 503-16. PMID 15537540 DOI: 10.1016/J.Cell.2004.10.028  0.459
2004 Gao L, Macara IG. Isoforms of the polarity protein par6 have distinct functions. The Journal of Biological Chemistry. 279: 41557-62. PMID 15292221 DOI: 10.1074/Jbc.M403723200  0.493
2004 Chen T, Brownawell AM, Macara IG. Nucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin-5. Molecular and Cellular Biology. 24: 6608-19. PMID 15254228 DOI: 10.1128/Mcb.24.15.6608-6619.2004  0.394
2004 Macchi P, Brownawell AM, Grunewald B, DesGroseillers L, Macara IG, Kiebler MA. The brain-specific double-stranded RNA-binding protein Staufen2: nucleolar accumulation and isoform-specific exportin-5-dependent export. The Journal of Biological Chemistry. 279: 31440-4. PMID 15166236 DOI: 10.1074/Jbc.C400226200  0.349
2004 Macara IG. Par proteins: partners in polarization. Current Biology : Cb. 14: R160-2. PMID 15027470 DOI: 10.1016/J.Cub.2004.01.048  0.37
2004 Macara IG. Parsing the polarity code. Nature Reviews. Molecular Cell Biology. 5: 220-31. PMID 14991002 DOI: 10.1038/Nrm1332  0.397
2004 Gwizdek C, Ossareh-Nazari B, Brownawell AM, Evers S, Macara IG, Dargemont C. Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3. The Journal of Biological Chemistry. 279: 884-91. PMID 14570900 DOI: 10.1074/Jbc.M306808200  0.325
2003 Stukenberg PT, Macara IG. The kinetochore NUPtials. Nature Cell Biology. 5: 945-7. PMID 14593413 DOI: 10.1038/Ncb1103-945  0.354
2003 Slepchenko BM, Schaff JC, Macara I, Loew LM. Quantitative cell biology with the Virtual Cell. Trends in Cell Biology. 13: 570-6. PMID 14573350 DOI: 10.1016/J.Tcb.2003.09.002  0.343
2003 Garrard SM, Capaldo CT, Gao L, Rosen MK, Macara IG, Tomchick DR. Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6. The Embo Journal. 22: 1125-33. PMID 12606577 DOI: 10.1093/Emboj/Cdg110  0.751
2003 Hurd TW, Gao L, Roh MH, Macara IG, Margolis B. Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Nature Cell Biology. 5: 137-42. PMID 12545177 DOI: 10.1038/Ncb923  0.478
2003 Narayanan A, Eifert J, Marfatia KA, Macara IG, Corbett AH, Terns RM, Terns MP. Nuclear RanGTP is not required for targeting small nucleolar RNAs to the nucleolus. Journal of Cell Science. 116: 177-86. PMID 12456727 DOI: 10.1242/Jcs.00176  0.382
2003 Sheffield PJ, Oliver CJ, Kremer BE, Sheng S, Shao Z, Macara IG. Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments. The Journal of Biological Chemistry. 278: 3483-8. PMID 12446710 DOI: 10.1074/Jbc.M209701200  0.771
2002 Macara IG, Baldarelli R, Field CM, Glotzer M, Hayashi Y, Hsu SC, Kennedy MB, Kinoshita M, Longtine M, Low C, Maltais LJ, McKenzie L, Mitchison TJ, Nishikawa T, Noda M, et al. Mammalian septins nomenclature. Molecular Biology of the Cell. 13: 4111-3. PMID 12475938 DOI: 10.1091/Mbc.E02-07-0438  0.737
2002 Du Q, Taylor L, Compton DA, Macara IG. LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation. Current Biology : Cb. 12: 1928-33. PMID 12445386 DOI: 10.1016/S0960-9822(02)01298-8  0.477
2002 Gao L, Macara IG, Joberty G. Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties. Gene. 294: 99-107. PMID 12234671 DOI: 10.1016/S0378-1119(02)00681-9  0.475
2002 Lindsay ME, Plafker K, Smith AE, Clurman BE, Macara IG. Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import. Cell. 110: 349-60. PMID 12176322 DOI: 10.1016/S0092-8674(02)00836-X  0.373
2002 Brugnera E, Haney L, Grimsley C, Lu M, Walk SF, Tosello-Trampont AC, Macara IG, Madhani H, Fink GR, Ravichandran KS. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nature Cell Biology. 4: 574-82. PMID 12134158 DOI: 10.1038/Ncb824  0.446
2002 Brownawell AM, Holaska JM, Macara IG, Paschal BM. The use of permeabilized cell systems to study nuclear transport. Methods in Molecular Biology (Clifton, N.J.). 189: 209-29. PMID 12094589 DOI: 10.1385/1-59259-281-3:209  0.307
2002 Plafker K, Macara IG. Fluorescence resonance energy transfer biosensors that detect Ran conformational changes and a Ran x GDP-importin-beta -RanBP1 complex in vitro and in intact cells. The Journal of Biological Chemistry. 277: 30121-7. PMID 12034733 DOI: 10.1074/Jbc.M203006200  0.365
2002 Nemergut ME, Lindsay ME, Brownawell AM, Macara IG. Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. The Journal of Biological Chemistry. 277: 17385-8. PMID 11932251 DOI: 10.1074/Jbc.C100620200  0.722
2002 Gao L, Joberty G, Macara IG. Assembly of epithelial tight junctions is negatively regulated by Par6. Current Biology : Cb. 12: 221-5. PMID 11839275 DOI: 10.1016/S0960-9822(01)00663-7  0.501
2002 Plafker SM, Macara IG. Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11. Molecular and Cellular Biology. 22: 1266-75. PMID 11809816 DOI: 10.1128/Mcb.22.4.1266-1275.2002  0.433
2002 Smith AE, Slepchenko BM, Schaff JC, Loew LM, Macara IG. Systems analysis of Ran transport. Science (New York, N.Y.). 295: 488-91. PMID 11799242 DOI: 10.1126/Science.1064732  0.328
2002 Brownawell AM, Macara IG. Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins. The Journal of Cell Biology. 156: 53-64. PMID 11777942 DOI: 10.1083/Jcb.200110082  0.429
2002 Macara IG. Transport into and out of the nucleus. Microbiology and Molecular Biology Reviews : Mmbr. 65: 570-94, table of con. PMID 11729264 DOI: 10.1128/Mmbr.65.4.570-594.2001  0.387
2001 Du Q, Stukenberg PT, Macara IG. A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nature Cell Biology. 3: 1069-75. PMID 11781568 DOI: 10.1038/Ncb1201-1069  0.455
2001 Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 107: 27-41. PMID 11595183 DOI: 10.1016/S0092-8674(01)00520-7  0.724
2001 Joberty G, Perlungher RR, Sheffield PJ, Kinoshita M, Noda M, Haystead T, Macara IG. Borg proteins control septin organization and are negatively regulated by Cdc42 Nature Cell Biology. 3: 861-866. PMID 11584266 DOI: 10.1038/Ncb1001-861  0.446
2001 Lindsay ME, Holaska JM, Welch K, Paschal BM, Macara IG. Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export. The Journal of Cell Biology. 153: 1391-402. PMID 11425870 DOI: 10.1083/Jcb.153.7.1391  0.444
2001 Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG. Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B Science. 292: 1540-1543. PMID 11375490 DOI: 10.1126/Science.292.5521.1540  0.688
2001 Brownawell AM, Kops GJ, Macara IG, Burgering BM. Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. Molecular and Cellular Biology. 21: 3534-46. PMID 11313479 DOI: 10.1128/Mcb.21.10.3534-3546.2001  0.392
2001 Neudauer CL, Joberty G, Macara IG. PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10. Biochemical and Biophysical Research Communications. 280: 541-7. PMID 11162552 DOI: 10.1006/Bbrc.2000.4160  0.419
2001 Neudauer CL, Macara IG. Purification and biochemical characterization of TC10. Methods in Enzymology. 325: 3-14. PMID 11036587 DOI: 10.1016/S0076-6879(00)25426-8  0.352
2000 Plafker SM, Macara IG. Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2. The Embo Journal. 19: 5502-13. PMID 11032817 DOI: 10.1093/Emboj/19.20.5502  0.378
2000 Joberty G, Petersen C, Gao L, Macara IG. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nature Cell Biology. 2: 531-9. PMID 10934474 DOI: 10.1038/35019573  0.463
2000 Nemergut ME, Macara IG. Nuclear import of the ran exchange factor, RCC1, is mediated by at least two distinct mechanisms. The Journal of Cell Biology. 149: 835-50. PMID 10811825 DOI: 10.1083/Jcb.149.4.835  0.714
2000 Plafker K, Macara IG. Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1. Molecular and Cellular Biology. 20: 3510-21. PMID 10779340 DOI: 10.1128/Mcb.20.10.3510-3521.2000  0.451
2000 Petersen C, Orem N, Trueheart J, Thorner JW, Macara IG. Random mutagenesis and functional analysis of the Ran-binding protein, RanBP1. The Journal of Biological Chemistry. 275: 4081-91. PMID 10660567 DOI: 10.1074/Jbc.275.6.4081  0.415
2000 Welch K, Franke J, Köhler M, Macara IG. RanBP3 contains an unusual nuclear localization signal that is imported preferentially by importin-alpha3. Molecular and Cellular Biology. 19: 8400-11. PMID 10567565 DOI: 10.1128/Mcb.19.12.8400  0.348
2000 Joberty G, Perlungher RR, Macara IG. The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins. Molecular and Cellular Biology. 19: 6585-97. PMID 10490598 DOI: 10.1128/Mcb.19.10.6585  0.486
1999 Macara IG. Nuclear transport: randy couples. Current Biology : Cb. 9: R436-9. PMID 10375521 DOI: 10.1016/S0960-9822(99)80275-9  0.376
1999 Smith A, Brownawell A, Macara IG. Nuclear import of Ran is mediated by the transport factor NTF2. Current Biology : Cb. 8: 1403-6. PMID 9889103 DOI: 10.1016/S0960-9822(98)00023-2  0.428
1999 Tatsis N, Lannigan DA, Macara IG. The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain. The Journal of Biological Chemistry. 273: 34631-8. PMID 9852136 DOI: 10.1074/Jbc.273.51.34631  0.385
1998 Neudauer CL, Joberty G, Tatsis N, Macara IG. Distinct cellular effects and interactions of the Rho-family GTPase TC10. Current Biology : Cb. 8: 1151-60. PMID 9799731 DOI: 10.1016/S0960-9822(07)00486-1  0.363
1997 Kuhlmann J, Macara I, Wittinghofer A. Dynamic and equilibrium studies on the interaction of Ran with its effector, RanBP1. Biochemistry. 36: 12027-35. PMID 9315840 DOI: 10.1021/Bi970524K  0.415
1997 Chung SH, Stabila P, Macara IG, Holz RW. Importance of the Rab3a-GTP binding domain for the intracellular stability and function of Rabphilin3a in secretion. Journal of Neurochemistry. 69: 164-73. PMID 9202307 DOI: 10.1046/J.1471-4159.1997.69010164.X  0.329
1997 Richards SA, Carey KL, Macara IG. Requirement of guanosine triphosphate-bound ran for signal-mediated nuclear protein export. Science (New York, N.Y.). 276: 1842-4. PMID 9188526 DOI: 10.1126/Science.276.5320.1842  0.454
1996 Lounsbury KM, Richards SA, Carey KL, Macara IG. Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization. The Journal of Biological Chemistry. 271: 32834-41. PMID 8955121 DOI: 10.1074/jbc.271.51.32834  0.353
1996 Richards SA, Lounsbury KM, Carey KL, Macara IG. A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1. The Journal of Cell Biology. 134: 1157-68. PMID 8794858 DOI: 10.1083/JCB.134.5.1157  0.358
1996 Carey KL, Richards SA, Lounsbury KM, Macara IG. Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import. The Journal of Cell Biology. 133: 985-96. PMID 8655589 DOI: 10.1083/jcb.133.5.985  0.323
1996 Lounsbury KM, Richards SA, Perlungher RR, Macara IG. Ran binding domains promote the interaction of Ran with p97/beta-karyopherin, linking the docking and translocation steps of nuclear import. The Journal of Biological Chemistry. 271: 2357-60. PMID 8576188 DOI: 10.1074/jbc.271.5.2357  0.31
1995 Richards SA, Lounsbury KM, Macara IG. The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1. The Journal of Biological Chemistry. 270: 14405-11. PMID 7782302 DOI: 10.1074/JBC.270.24.14405  0.338
1992 Burstein ES, Macara IG. Characterization of a guanine nucleotide-releasing factor and a GTPase-activating protein that are specific for the ras-related protein p25rab3A. Proceedings of the National Academy of Sciences of the United States of America. 89: 1154-8. PMID 1311081 DOI: 10.1073/Pnas.89.4.1154  0.331
1982 Macara IG, Cantley LC. Mechanism of anion exchange across the red cell membrane by band 3: interactions between stilbenedisulfonate and NAP-taurine binding sites. Biochemistry. 20: 5695-701. PMID 7295699 DOI: 10.1021/Bi00523A009  0.324
1982 Macara IG, Cantley LC. Interactions between transport inhibitors at the anion binding sites of the band 3 dimer. Biochemistry. 20: 5095-105. PMID 7295667 DOI: 10.1021/Bi00521A001  0.321
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