| Year |
Citation |
Score |
| 2009 |
Ura Y, Beierle JM, Leman LJ, Orgel LE, Ghadiri MR. Self-assembling sequence-adaptive peptide nucleic acids. Science (New York, N.Y.). 325: 73-7. PMID 19520909 DOI: 10.1126/Science.1174577 |
0.34 |
|
| 2006 |
Leman LJ, Orgel LE, Ghadiri MR. Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide. Journal of the American Chemical Society. 128: 20-1. PMID 16390101 DOI: 10.1021/Ja056036E |
0.353 |
|
| 2006 |
Joyce GF, Orgel LE. 2 Progress toward Understanding the Origin of the RNA World Cold Spring Harbor Monograph Archive. 43: 23-56. DOI: 10.1101/087969739.43.23 |
0.545 |
|
| 2004 |
Leman L, Orgel L, Ghadiri MR. Carbonyl sulfide-mediated prebiotic formation of peptides. Science (New York, N.Y.). 306: 283-6. PMID 15472077 DOI: 10.1126/Science.1102722 |
0.342 |
|
| 2004 |
Orgel LE. Prebiotic adenine revisited: Eutectics and photochemistry Origins of Life and Evolution of the Biosphere. 34: 361-369. PMID 15279171 DOI: 10.1023/B:Orig.0000029882.52156.C2 |
0.339 |
|
| 2004 |
Orgel LE. Prebiotic chemistry and the origin of the RNA world Critical Reviews in Biochemistry and Molecular Biology. 39: 99-123. PMID 15217990 DOI: 10.1080/10409230490460765 |
0.333 |
|
| 2003 |
Orgel LE. Some consequences of the RNA world hypothesis Origins of Life and Evolution of the Biosphere. 33: 211-218. PMID 12967268 DOI: 10.1023/A:1024616317965 |
0.325 |
|
| 2002 |
Orgel LE. Is cyanoacetylene prebiotic? Origins of Life and Evolution of the Biosphere. 32: 279-281. PMID 12227432 DOI: 10.1023/A:1016509009433 |
0.309 |
|
| 2002 |
Hill A, Orgel LE. Synthesis of adenine from HCN tetramer and ammonium formate Origins of Life and Evolution of the Biosphere. 32: 99-102. PMID 12185678 DOI: 10.1023/A:1016070723772 |
0.334 |
|
| 2002 |
Hill A, Orgel LE. Trimetaphosphate-induced addition of aspartic acid to oligo(glutamic acid)s Helvetica Chimica Acta. 85: 4244-4254. DOI: 10.1002/Hlca.200290009 |
0.319 |
|
| 2001 |
Wen K, Orgel LE. The specificity of peptide chain extension by N-carboxyanhydrides Origins of Life and Evolution of the Biosphere. 31: 241-248. PMID 11434103 DOI: 10.1023/A:1010651618537 |
0.307 |
|
| 2001 |
Gao K, Orgel LE. Hydrolysis of tRNAPhe on suspensions of amino acids Helvetica Chimica Acta. 84: 1347-1354. DOI: 10.1002/1522-2675(20010613)84:6<1347::Aid-Hlca1347>3.0.Co;2-2 |
0.354 |
|
| 2000 |
Kozlov IA, Orgel LE, Nielsen PE. Remote Enantioselection Transmitted by an Achiral Peptide Nucleic Acid Backbone. Angewandte Chemie (International Ed. in English). 39: 4292-4295. PMID 29711900 DOI: 10.1002/1521-3773(20001201)39:23<4292::Aid-Anie4292>3.0.Co;2-S |
0.36 |
|
| 2000 |
Zielinski M, Kozlov IA, Orgel LE. A comparison of RNA with DNA in template-directed synthesis Helvetica Chimica Acta. 83: 1678-1684. PMID 11543568 DOI: 10.1002/1522-2675(20000809)83:8<1678::Aid-Hlca1678>3.0.Co;2-P |
0.345 |
|
| 2000 |
Orgel L. A simpler nucleic acid Science. 290: 1306-1307. PMID 11185405 DOI: 10.1126/Science.290.5495.1306 |
0.342 |
|
| 2000 |
Orgel LE. Self-organizing biochemical cycles Proceedings of the National Academy of Sciences of the United States of America. 97: 12503-12507. PMID 11058157 DOI: 10.1073/Pnas.220406697 |
0.303 |
|
| 2000 |
Maurel MC, Orgel LE. Oligomerization of α-thioglutamic acid Origins of Life and Evolution of the Biosphere. 30: 423-430. PMID 11002888 DOI: 10.1023/A:1006728514362 |
0.337 |
|
| 2000 |
Gao K, Orgel LE. Polyphosphorylation and non-enzymatic template-directed ligation of oligonucleotides Origins of Life and Evolution of the Biosphere. 30: 45-51. PMID 10836264 DOI: 10.1023/A:1006683507864 |
0.337 |
|
| 2000 |
Kozlov IA, Zielinski M, Allart B, Kerremans L, Van Aerschot A, Busson R, Herdewijn P, Orgel LE. Nonenzymatic template-directed reactions on altritol oligomers, preorganized analogues of oligonucleotides Chemistry - a European Journal. 6: 151-155. PMID 10747399 DOI: 10.1002/(Sici)1521-3765(20000103)6:1<151::Aid-Chem151>3.0.Co;2-H |
0.378 |
|
| 2000 |
Kozlov JA, Orgel LE. Nonenzymatic template-directed synthesis of RNA from monomers Molekulyarnaya Biologiya. 34: 921-930. DOI: 10.1023/A:1026663422976 |
0.364 |
|
| 1999 |
Kozlov IA, Politis PK, Van Aerschot A, Busson R, Herdewijn P, Orgel LE. Nonenzymatic synthesis of RNA and DNA oligomers on hexitol nucleic acid templates: The importance of the a structure Journal of the American Chemical Society. 121: 2653-2656. PMID 11543583 DOI: 10.1021/Ja983958R |
0.378 |
|
| 1999 |
Kozlov IA, Orgel LE. Nonenzymatic oligomerization reactions on templates containing inosinic acid or diaminopurine nucleotide residues Helvetica Chimica Acta. 82: 1799-1805. PMID 11543571 DOI: 10.1002/(Sici)1522-2675(19991110)82:11<1799::Aid-Hlca1799>3.0.Co;2-S |
0.4 |
|
| 1999 |
Kozlov IA, De Bouvere B, Van Aerschot A, Herdewijn P, Orgel LE. Efficient transfer of information from hexitol nucleic acids to RNA during nonenzymatic oligomerization Journal of the American Chemical Society. 121: 5856-5859. PMID 11542282 DOI: 10.1021/Ja990440U |
0.369 |
|
| 1999 |
Kozlov IA, Politis PK, Pitsch S, Herdewijn P, Orgel LE. A highly enantio-selective hexitol nucleic acid template for nonenzymatic oligoguanylate synthesis [11] Journal of the American Chemical Society. 121: 1108-1109. PMID 11541447 DOI: 10.1021/Ja9836489 |
0.377 |
|
| 1999 |
Kozlov IA, Orgel LE. Oligomerization of deoxyguanosine 5'-phosphoro-2-methylimidazolide on a polycytidylate template Origins of Life and Evolution of the Biosphere. 29: 593-595. PMID 10666742 DOI: 10.1023/A:1006666926870 |
0.327 |
|
| 1999 |
Gao K, Orgel LE. Nucleic acid duplexes incorporating a dissociable covalent base pair Proceedings of the National Academy of Sciences of the United States of America. 96: 14837-14842. PMID 10611299 DOI: 10.1073/Pnas.96.26.14837 |
0.356 |
|
| 1999 |
Hill AR, Orgel LE. Oligomerization of L-γ-carboxyglutamic acid Origins of Life and Evolution of the Biosphere. 29: 115-122. PMID 10227198 DOI: 10.1023/A:1006512304332 |
0.334 |
|
| 1999 |
Arrhenius G, Bada JL, Joyce GF, Lazcano A, Miller S, Orgel LE. Origin and ancestor: separate environments. Science (New York, N.Y.). 283: 792. PMID 10049121 DOI: 10.1126/Science.283.5403.791C |
0.485 |
|
| 1999 |
Joyce GF, Orgel LE. 2 Prospects for Understanding the Origin of the RNA World Cold Spring Harbor Monograph Archive. 37: 49-77. DOI: 10.1101/087969589.37.49 |
0.547 |
|
| 1998 |
Koppitz M, Nielsen PE, Orgel LE. Formation of oligonucleotide-PNA-chimeras by template-directed ligation Journal of the American Chemical Society. 120: 4563-4569. PMID 11541746 DOI: 10.1021/Ja974190Y |
0.351 |
|
| 1998 |
Joyce GF, Orgel LE. The origins of life--a status report. The American Biology Teacher. 60: 10-2. PMID 11541103 DOI: 10.2307/4450404 |
0.504 |
|
| 1998 |
Liu R, Orgel LE. Polymerization of β-amino acids in aqueous solution Origins of Life and Evolution of the Biosphere. 28: 47-60. PMID 11536855 DOI: 10.1023/A:1006580918298 |
0.304 |
|
| 1998 |
Orgel LE. The origin of life-a review of facts and speculations Trends in Biochemical Sciences. 23: 491-495. PMID 9868373 DOI: 10.1016/S0968-0004(98)01300-0 |
0.32 |
|
| 1998 |
Liu R, Orgel LE. Polymerization on the rocks: β-amino acids and arginine Origins of Life and Evolution of the Biosphere. 28: 245-257. PMID 9611765 DOI: 10.1023/A:1006576213220 |
0.317 |
|
| 1998 |
Hill AR, Böhler C, Orgel LE. Polymerization on the rocks: negatively-charged α-amino acids Origins of Life and Evolution of the Biosphere. 28: 235-243. PMID 9611764 DOI: 10.1023/A:1006572112311 |
0.311 |
|
| 1998 |
Orgel LE. Polymerization on the rocks: theoretical introduction Origins of Life and Evolution of the Biosphere. 28: 227-234. PMID 9611763 DOI: 10.1023/A:1006595411403 |
0.34 |
|
| 1997 |
Liu R, Orgel LE. Efficient oligomerization of negatively-charged β-amino acids at -20 °C Journal of the American Chemical Society. 119: 4791-4792. PMID 11540426 DOI: 10.1021/Ja9702529 |
0.319 |
|
| 1997 |
Schmidt JG, Nielsen PE, Orgel LE. Enantiomeric cross-inhibition in the synthesis of oligonucleotides on a nonchiral template Journal of the American Chemical Society. 119: 1494-1495. PMID 11539924 DOI: 10.1021/Ja963563C |
0.38 |
|
| 1997 |
Schmidt JG, Nielsen PE, Orgel LE. Information transfer from peptide nucleic acids to RNA by template-directed syntheses Nucleic Acids Research. 25: 4797-4802. PMID 9365259 DOI: 10.1093/Nar/25.23.4797 |
0.393 |
|
| 1997 |
Jürgen G, Schmidt LC, Nielsen PE, Orgel LE. Information transfer from DNA to peptide nucleic acids by template-directed syntheses Nucleic Acids Research. 25: 4792-4796. PMID 9365258 DOI: 10.1093/Nar/25.23.4792 |
0.367 |
|
| 1997 |
Liu R, Orgel LE. Oxidative acylation using thioacids Nature. 389: 52-54. PMID 9288964 DOI: 10.1038/37944 |
0.362 |
|
| 1997 |
Bruick RK, Koppitz M, Joyce GF, Orgel LE. A simple procedure for constructing 5'-amino-terminated oligodeoxynucleotides in aqueous solution. Nucleic Acids Research. 25: 1309-10. PMID 9092646 DOI: 10.1093/Nar/25.6.1309 |
0.576 |
|
| 1996 |
Hill AR, Orgel LE. Oligomerization of negatively-charged amino acids by carbonyldiimidazole Origins of Life and Evolution of the Biosphere. 26: 539-545. PMID 11536772 DOI: 10.1007/Bf01808219 |
0.354 |
|
| 1996 |
Kolb V, Orgel LE. Phosphorylation of glyceric acid in aqueous solution using trimetaphosphate Origins of Life and Evolution of the Biosphere. 26: 7-13. PMID 11536746 DOI: 10.1007/Bf01808156 |
0.327 |
|
| 1996 |
Böhler C, Hill AR, Orgel LE. Catalysis of the oligomerization of o-phospho-serine, aspartic acid, or glutamic acid by cationic micelles Origins of Life and Evolution of the Biosphere. 26: 1-5. PMID 11536743 DOI: 10.1007/Bf01808155 |
0.307 |
|
| 1996 |
Ferris JP, Hill AR, Liu R, Orgel LE. Synthesis of long prebiotic oligomers on mineral surfaces. Nature. 381: 59-61. PMID 8609988 DOI: 10.1038/381059A0 |
0.343 |
|
| 1996 |
Schmidt JG, Nielsen PE, Orgel LE. PNAs — A prebiotic template? enantiomeric cross-inhibition on the nonchiral template and the rearrangement of peptide nucleic acids in aqueous solution Origins of Life and Evolution of the Biosphere. 26: 421-422. DOI: 10.1007/Bf02459847 |
0.315 |
|
| 1996 |
Liu R, Orgel LE. Polymerization of amino acids Origins of Life and Evolution of the Biosphere. 26: 373-373. DOI: 10.1007/Bf02459816 |
0.306 |
|
| 1996 |
Bada JL, Arrhenlus G, Miller SL, Orgel L, Joyce G. The NASA specialized center of research and training (NSCORT) in exobiology Origins of Life and Evolution of the Biosphere. 26: 318-319. DOI: 10.1007/Bf02459783 |
0.468 |
|
| 1995 |
Orgel LE. Unnatural Selection in Chemical Systems Accounts of Chemical Research. 28: 109-118. PMID 11542502 DOI: 10.1021/Ar00051A004 |
0.333 |
|
| 1995 |
Kolb V, Orgel LE. Oligonucleotides as probes for studying polymerization reactions in dilute aqueous solution: II. Polycondensations Journal of Molecular Evolution. 40: 115-119. PMID 7699717 DOI: 10.1007/Bf00167106 |
0.312 |
|
| 1995 |
Bohler C, Nielsen PE, Orgel LE. Template switching between PNA and RNA oligonucleotides Nature. 376: 578-581. PMID 7543656 DOI: 10.1038/376578A0 |
0.336 |
|
| 1995 |
Liu R, Orgel LE. Enzymatic synthesis of polymers containing nicotinamide mononucleotide Nucleic Acids Research. 23: 3742-3749. PMID 7479005 DOI: 10.1093/Nar/23.18.3742 |
0.338 |
|
| 1994 |
Zieboll G, Orgel LE. The use of gel electrophoresis to study the reactions of activated amino acids with oligonucleotides Journal of Molecular Evolution. 38: 561-565. PMID 11539447 DOI: 10.1007/Bf00175875 |
0.355 |
|
| 1994 |
Kolb V, Orgel LE. Oligonucleotides as probes for studying polymerization reactions in dilute aqueous solution. Journal of Molecular Evolution. 38: 433-7. PMID 11539445 DOI: 10.1007/Bf00178842 |
0.31 |
|
| 1994 |
Harada K, Orgel LE. In vitro selection of optimal DNA substrates for ligation by a water- soluble carbodiimide Journal of Molecular Evolution. 38: 558-560. PMID 8083882 DOI: 10.1007/Bf00175874 |
0.315 |
|
| 1994 |
Rembold H, Robins RK, Seela F, Orgel LE. Polycytidylate and poly(7-deazaguanylate): a pair of complementary templates. Journal of Molecular Evolution. 38: 211-4. PMID 8006989 DOI: 10.1007/Bf00176083 |
0.412 |
|
| 1994 |
Rembold H, Orgel LE. Single-strand regions of poly(G) act as templates for oligo(C) synthesis Journal of Molecular Evolution. 38: 205-210. PMID 8006988 DOI: 10.1007/Bf00176082 |
0.392 |
|
| 1993 |
Hill AR, Orgel LE, Wu T. The limits of template-directed synthesis with nucleoside-5′-phosphoro(2-methyl)imidazolides Origins of Life and Evolution of the Biosphere. 23: 285-290. PMID 8115162 DOI: 10.1007/Bf01582078 |
0.333 |
|
| 1993 |
Joyce GF, Orgel LE. 1 Prospects for Understanding the Origin of the RNA World Cold Spring Harbor Monograph Archive. 24: 1-25. DOI: 10.1101/087969380.24.1 |
0.546 |
|
| 1992 |
Wu T, Orgel LE. Nonenzymatic template-directed synthesis on oligodeoxycytidylate sequences in hairpin oligonucleotides Journal of the American Chemical Society. 114: 317-322. PMID 11540927 DOI: 10.1021/Ja00027A040 |
0.369 |
|
| 1992 |
Wu T, Orgel LE. Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues. Journal of the American Chemical Society. 114: 7963-9. PMID 11538876 DOI: 10.1021/Ja00047A001 |
0.336 |
|
| 1992 |
Wu T, Orgel LE. Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 2. Templates containing cytidine and guanosine residues Journal of the American Chemical Society. 114: 5496-5501. PMID 11538402 DOI: 10.1021/Ja00040A002 |
0.356 |
|
| 1991 |
Harada K, Orgel LE. The cyclization of arabinosyladenine-5′-phosphorimidazolide Journal of Molecular Evolution. 32: 358-359. PMID 11538262 DOI: 10.1007/Bf02101274 |
0.316 |
|
| 1991 |
Wu T, Orgel LE. Disulfide-linked oligonucleotide phosphorothioates: Novel analogues of nucleic acids Journal of Molecular Evolution. 32: 274-277. PMID 11538257 DOI: 10.1007/Bf02102183 |
0.329 |
|
| 1991 |
Rodriguez L, Orgel LE. Pyrophosphate formation as the most efficient condensation reaction of activated nucleotides Journal of Molecular Evolution. 32: 101-104. PMID 1848905 DOI: 10.1007/Bf02515382 |
0.362 |
|
| 1991 |
Rodriguez L, Orgel LE. Template-directed extension of a guanosine 5′-phosphate covalently attached to an oligodeoxycytidylate template Journal of Molecular Evolution. 33: 477-482. PMID 1779431 DOI: 10.1007/Bf02102800 |
0.333 |
|
| 1991 |
Hill AR, Kumar S, Patil VD, Leonard NJ, Orgel LE. Which 3-ribofuranosyl-substituted purine 5'-phosphates undergo template-directed oligomerization? Journal of Molecular Evolution. 32: 447-53. PMID 1651397 DOI: 10.1007/Bf02102646 |
0.377 |
|
| 1991 |
Rodriguez L, Orgel LE. Acceleration of the template-directed reactions of nucleoside 5′-phosphorimidazolides by acylation Journal of Molecular Evolution. 32: 278-281. PMID 1650843 DOI: 10.1007/Bf02102184 |
0.368 |
|
| 1990 |
Tohidi M, Orgel LE. Polymerization of the cyclic pyrophosphates of nucleosides and their analogues. Journal of Molecular Evolution. 30: 97-103. PMID 11540911 DOI: 10.1007/Bf02099935 |
0.341 |
|
| 1990 |
Harada K, Orgel LE. Synthesis of 5'-deoxy-5'-nucleosideacetic acid derivatives Nucleosides and Nucleotides. 9: 771-785. PMID 11538686 DOI: 10.1080/15257779008043143 |
0.373 |
|
| 1990 |
Harada K, Orgel LE. Template-directed oligomerization of 5'-deoxy-5'-nucleosideacetic acid derivatives. Origins of Life and Evolution of the Biosphere : the Journal of the International Society For the Study of the Origin of Life. 20: 151-60. PMID 11537407 DOI: 10.1007/Bf01808276 |
0.37 |
|
| 1990 |
Chu BC, Orgel LE. A simple procedure for cross-linking complementary oligonucleotides. Dna and Cell Biology. 9: 71-6. PMID 2180430 DOI: 10.1089/Dna.1990.9.71 |
0.309 |
|
| 1990 |
Cheikh AB, Orgel LE. Polymerization of amino acids containing nucleotide bases. Journal of Molecular Evolution. 30: 315-21. PMID 2111845 DOI: 10.1007/Bf02101885 |
0.351 |
|
| 1989 |
Tohidi M, Orgel LE. Some acyclic analogues of nucleotides and their template-directed reactions. Journal of Molecular Evolution. 28: 367-73. PMID 11542188 DOI: 10.1007/Bf02603071 |
0.37 |
|
| 1989 |
Zielinski WS, Orgel LE. Polymerization of a monomeric guanosine derivative in a hydrogen- bonded aggregate. Journal of Molecular Evolution. 29: 367-9. PMID 2514276 DOI: 10.1007/Bf02103623 |
0.322 |
|
| 1989 |
Zielinski WS, Orgel LE. The template properties of tetranucleoside triphosphoramidates having cytosine-guanosine residues. Journal of Molecular Evolution. 29: 281-3. PMID 2514268 DOI: 10.1007/Bf02103614 |
0.319 |
|
| 1989 |
Ng KE, Orgel LE. Reaction on alternating GC oligonucleotide templates. Journal of Molecular Evolution. 29: 101-7. PMID 2509713 DOI: 10.1007/Bf02100109 |
0.319 |
|
| 1989 |
Orgel LE. The origin of polynucleotide-directed protein synthesis. Journal of Molecular Evolution. 29: 465-74. PMID 2482368 DOI: 10.1007/Bf02602917 |
0.369 |
|
| 1989 |
Chu BC, Orgel LE. Inhibition of DNA synthesis by cross-linking the template to platinum-thiol derivatives of complementary oligodeoxynucleotides. Nucleic Acids Research. 17: 4783-98. PMID 2473441 DOI: 10.1093/Nar/17.12.4783 |
0.324 |
|
| 1989 |
Harada K, Orgel LE. Oligomerization of 5′-deoxy-5′-nucleosideacetic acid derivatives Origins of Life and Evolution of the Biosphere. 19: 351-352. DOI: 10.1007/Bf02388888 |
0.345 |
|
| 1989 |
Orgel LE. Abiogenic synthesis of polynucleotides Origins of Life and Evolution of the Biosphere. 19: 319-319. DOI: 10.1007/Bf02388869 |
0.327 |
|
| 1988 |
Chu BCF, Orgel LE. Ligation of oligonucleotides to nucleic acids or proteins via disulfide bonds Nucleic Acids Research. 16: 3671-3691. PMID 3375070 DOI: 10.1093/Nar/16.9.3671 |
0.326 |
|
| 1988 |
Hill AR, Nord LD, Orgel LE, Robins RK. Cyclization of nucleotide analogues as an obstacle to polymerization. Journal of Molecular Evolution. 28: 170-1. PMID 3148737 DOI: 10.1007/Bf02143509 |
0.349 |
|
| 1988 |
Hill AR, Kumar S, Leonard NJ, Orgel LE. Template-directed oligomerization of 3-isoadenosine 5'-phosphate. Journal of Molecular Evolution. 27: 91-5. PMID 3137356 DOI: 10.1007/Bf02138366 |
0.367 |
|
| 1988 |
Joyce GF, Orgel LE. Non-enzymatic template-directed synthesis on RNA random copolymers. Poly(C,A) templates. Journal of Molecular Biology. 202: 677-81. PMID 2459395 DOI: 10.1016/0022-2836(88)90297-5 |
0.548 |
|
| 1987 |
Tohidi M, Zielinski WS, Chen CHB, Orgel LE. Oligomerization of 3′-amino-3′-deoxyguanosine-5′-phosphorimidazolidate on a d(CpCpCpCpC) template Journal of Molecular Evolution. 25: 97-99. PMID 11542079 DOI: 10.1007/Bf02101750 |
0.383 |
|
| 1987 |
Acevedo OL, Orgel LE. Non-enzymatic transcription of an oligodeoxynucleotide 14 residues long Journal of Molecular Biology. 197: 187-193. PMID 3681994 DOI: 10.1016/0022-2836(87)90117-3 |
0.367 |
|
| 1987 |
Zielinski WS, Orgel LE. Autocatalytic synthesis of a tetranucleotide analogue Nature. 327: 346-347. PMID 3587350 DOI: 10.1038/327346A0 |
0.356 |
|
| 1987 |
Joyce GF, Schwartz AW, Miller SL, Orgel LE. The case for an ancestral genetic system involving simple analogues of the nucleotides. Proceedings of the National Academy of Sciences of the United States of America. 84: 4398-402. PMID 2440020 DOI: 10.1073/Pnas.84.13.4398 |
0.578 |
|
| 1986 |
Acevedo OL, Orgel LE. Template-directed oligonucleotide ligation on hydroxylapatite Nature. 321: 790-792. PMID 11540863 DOI: 10.1038/321790A0 |
0.34 |
|
| 1986 |
Orgel LE. Did template-directed nucleation precede molecular replication? Origins of Life and Evolution of the Biosphere. 17: 27-34. PMID 3796964 DOI: 10.1007/Bf01809810 |
0.307 |
|
| 1986 |
Grzeskowiak K, Orgel LE. Template-directed synthesis on short oligoribocytidylates Journal of Molecular Evolution. 23: 287-289. PMID 3104599 DOI: 10.1007/Bf02100635 |
0.311 |
|
| 1986 |
Haertle T, Orgel LE. The template properties of some oligodeoxynucleotides containing cytidine and guanosine Journal of Molecular Evolution. 23: 108-112. PMID 3091841 DOI: 10.1007/Bf02099904 |
0.346 |
|
| 1986 |
Haertle T, Orgel LE. Template-directed synthesis on the oligonucleotide d(C7-G-C7) Journal of Molecular Biology. 188: 77-80. PMID 3012097 DOI: 10.1016/0022-2836(86)90482-1 |
0.317 |
|
| 1986 |
Orgel LE. RNA catalysis and the origins of life Journal of Theoretical Biology. 123: 127-149. PMID 2442564 DOI: 10.1016/S0022-5193(86)80149-7 |
0.322 |
|
| 1986 |
Chu BC, Kramer FR, Orgel LE. Synthesis of an amplifiable reporter RNA for bioassays. Nucleic Acids Research. 14: 5591-603. PMID 2426657 DOI: 10.1093/Nar/14.14.5591 |
0.321 |
|
| 1986 |
Joyce GF, Orgel LE. Non-enzymic template-directed synthesis on RNA random copolymers. Poly(C, G) templates. Journal of Molecular Biology. 188: 433-41. PMID 2426455 DOI: 10.1016/0022-2836(86)90166-X |
0.527 |
|
| 1986 |
Zielinski WS, Orgel LE. Studies of the oligomerization and properties of oligonucleotide analogs bearing (3′->5′) phosphoramidate backbone Origins of Life and Evolution of Biospheres. 16: 470-470. DOI: 10.1007/Bf02422140 |
0.345 |
|
| 1986 |
Joyce GF, Orgel LE. Consequences of template self-structure in poly(C,G)-directed synthesis of oligo(G,C)s Origins of Life and Evolution of the Biosphere. 16: 458-458. DOI: 10.1007/Bf02422133 |
0.538 |
|
| 1986 |
Joyce GF, Orgel LE, Miller SL. Chiral selection in template-directed RNA synthesis and the case for a prochiral ancestor of RNA Origins of Life and Evolution of the Biosphere. 16: 445-445. DOI: 10.1007/Bf02422125 |
0.598 |
|
| 1985 |
Schwartz AW, Orgel LE. Template-directed synthesis of novel, nucleic acid-like structures Science. 228: 585-587. PMID 11541994 DOI: 10.1126/Science.228.4699.585 |
0.416 |
|
| 1985 |
Schwartz AW, Orgel LE. Template-directed polynucleotide synthesis on mineral surfaces Journal of Molecular Evolution. 21: 299-300. PMID 6443132 DOI: 10.1007/Bf02102362 |
0.318 |
|
| 1985 |
Chen CB, Inoue T, Orgel LE. Template-directed synthesis on oligodeoxycytidylate and polydeoxycytidylate templates Journal of Molecular Biology. 181: 271-279. PMID 2984432 DOI: 10.1016/0022-2836(85)90091-9 |
0.405 |
|
| 1985 |
Zielinski WS, Orgel LE. Oligomerization of activated derivatives of 3′-amino-3′-deoxyguanosine on poly(C) and poly(DC) templates Nucleic Acids Research. 13: 2469-2484. DOI: 10.1093/Nar/13.7.2469 |
0.394 |
|
| 1984 |
Fakhrai H, Inoue T, Orgel LE. Temperature-dependence of the template-directed synthesis of oligoguanylates Tetrahedron. 40: 39-45. PMID 11540802 DOI: 10.1016/0040-4020(84)85101-7 |
0.344 |
|
| 1984 |
Joyce GF, Visser GM, van Boeckel CA, van Boom JH, Orgel LE, van Westrenen J. Chiral selection in poly(C)-directed synthesis of oligo(G). Nature. 310: 602-4. PMID 6462250 DOI: 10.1038/310602A0 |
0.579 |
|
| 1984 |
Grzeskowiak K, Webb TR, Orgel LE. Template-directed synthesis with 2-aminoadenosine Journal of Molecular Evolution. 21: 81-83. PMID 6442362 DOI: 10.1007/Bf02100631 |
0.36 |
|
| 1984 |
Chu BCF, Orgel LE. Preparation of ligation intermediates and related polynucleotide pyrophosphates Bba - Gene Structure and Expression. 782: 103-105. PMID 6326832 DOI: 10.1016/0167-4781(84)90111-8 |
0.347 |
|
| 1984 |
Joyce GF, Inoue T, Orgel LE. Non-enzymatic template-directed synthesis on RNA random copolymers. Poly(C, U) templates. Journal of Molecular Biology. 176: 279-306. PMID 6205154 DOI: 10.1016/0022-2836(84)90425-X |
0.595 |
|
| 1984 |
Inoue T, Joyce GF, Grzeskowiak K, Orgel LE, Brown JM, Reese CB. Template-directed synthesis on the pentanucleotide CpCpGpCpC. Journal of Molecular Biology. 178: 669-76. PMID 6092644 DOI: 10.1016/0022-2836(84)90244-4 |
0.689 |
|
| 1983 |
Inoue T, Orgel LE. A nonenzymatic RNA polymerase model Science. 219: 859-862. PMID 6186026 DOI: 10.1126/Science.6186026 |
0.384 |
|
| 1983 |
Chu BCF, Wahl GM, Orgel LE. Derivatization of unprotected polynucleotides Nucleic Acids Research. 11: 6513-6529. DOI: 10.1093/Nar/11.18.6513 |
0.349 |
|
| 1982 |
Inoue T, Orgel LE. Oligomerization of (guanosine 5′-phosphor)-2-methylimidazolide on poly(C). An RNA polymerase model Journal of Molecular Biology. 162: 201-217. PMID 6296405 DOI: 10.1016/0022-2836(82)90169-3 |
0.389 |
|
| 1982 |
Webb TR, Orgel LE. Template directed reactions of 2-aminoadenylic acid derivatives Nucleic Acids Research. 10: 4413-4422. DOI: 10.1093/Nar/10.14.4413 |
0.383 |
|
| 1981 |
Fakhrai H, van Roode JHG, Orgel LE. Synthesis of oligoguanylates on oligocytidylate templates Journal of Molecular Evolution. 17: 295-302. PMID 7277512 DOI: 10.1007/Bf01795751 |
0.356 |
|
| 1981 |
Lohrmann R, Bridson PK, Orgel LE. Condensation of activated diguanylates on a poly(C) template Journal of Molecular Evolution. 17: 303-306. PMID 6268800 DOI: 10.1007/Bf01795752 |
0.329 |
|
| 1981 |
Weber AL, Orgel LE. The effect of poly(C) on the formation of peptide bonds from the 2′(3′)-glycyl ester of a guanosine nucleotide Journal of Molecular Evolution. 17: 190-191. PMID 6267310 DOI: 10.1007/Bf01733914 |
0.303 |
|
| 1980 |
Gibbs D, Lohrmann R, Orgel LE. Template-directed synthesis and selective adsorption of oligoadenylates on hydroxyapatite Journal of Molecular Evolution. 15: 347-354. PMID 7411657 DOI: 10.1007/Bf01733141 |
0.306 |
|
| 1980 |
Bridson PK, Orgel LE. Catalysis of accurate poly(C)-directed synthesis of 3′-5′-linked oligoguanylates by Zn2+ Journal of Molecular Biology. 144: 567-577. PMID 6265649 DOI: 10.1016/0022-2836(80)90337-X |
0.362 |
|
| 1980 |
Lohrmann R, Orgel LE. Efficient catalysis of polycytidylic acid-directed oligoguanylate formation by Pb2+ Journal of Molecular Biology. 142: 555-567. PMID 6257910 DOI: 10.1016/0022-2836(80)90263-6 |
0.374 |
|
| 1980 |
Lohrmann R, Bridson PK, Orgel LE. Efficient metal-ion catalyzed template-directed oligonucleotide synthesis Science. 208: 1464-1465. PMID 6247762 DOI: 10.1126/Science.6247762 |
0.35 |
|
| 1979 |
Lohrmann R, Orgel LE. Self-condensation of activated dinucleotides on polynucleotide templates with alternating sequences Journal of Molecular Evolution. 14: 243-250. PMID 537104 DOI: 10.1007/Bf01732491 |
0.351 |
|
| 1979 |
Sleeper HL, Lohrmann R, Orgel LE. Template-directed synthesis of oligoadenylates catalyzed by Pb2+ ions Journal of Molecular Evolution. 13: 203-214. PMID 501744 DOI: 10.1007/Bf01739480 |
0.313 |
|
| 1979 |
Weber AL, Orgel LE. The formation of dipeptides from amino acids and the 2′(3′)-glycyl ester of an adenylate Journal of Molecular Evolution. 13: 185-191. PMID 501742 DOI: 10.1007/Bf01739478 |
0.319 |
|
| 1979 |
Sleeper HL, Orgel LE. The catalysis of nucleotide polymerization by compounds of divalent lead Journal of Molecular Evolution. 12: 357-364. PMID 448750 DOI: 10.1007/Bf01732030 |
0.309 |
|
| 1979 |
Lohrmann R, Orgel LE. Studies of oligoadenylate formation on a poly(U) template Journal of Molecular Evolution. 12: 237-257. PMID 220428 DOI: 10.1007/Bf01732341 |
0.351 |
|
| 1978 |
Ninio J, Orgel LE. Heteropolynucleotides as templates for non-enzymatic polymerizations Journal of Molecular Evolution. 12: 91-99. PMID 739554 DOI: 10.1007/Bf01733260 |
0.362 |
|
| 1978 |
Lohrmann R, Orgel LE. Formation of P1, P2-dinucleoside 5′-pyrophosphates under potentially prebiological conditions Journal of Molecular Evolution. 11: 17-23. PMID 207876 DOI: 10.1007/Bf01768021 |
0.302 |
|
| 1978 |
Weber AL, Orgel LE. Amino acid activation with adenosine 5′-phosphorimidazolide Journal of Molecular Evolution. 11: 9-16. PMID 26807 DOI: 10.1007/Bf01768020 |
0.343 |
|
| 1978 |
Lohrmann R, Orgel LE. Preferential formation of (2'-5')-linked internucleotide bonds in non-enzymatic reactions Tetrahedron. 34: 853-855. DOI: 10.1016/0040-4020(78)88129-0 |
0.328 |
|
| 1977 |
Lohrmann R, Orgel LE. Reactions of adenosine 5′-phosphorimidazolide with adenosine analogs on a polyuridylic acid template. The uniqueness of the 2′-3′-unsubstituted β-ribosyl system Journal of Molecular Biology. 113: 193-198. PMID 881733 DOI: 10.1016/0022-2836(77)90049-3 |
0.313 |
|
| 1977 |
Ehler KW, Girard E, Orgel LE. Reactions of polyfunctional amino acids with N,N′-carbonyldiimidazole in aqueous solution oligopeptide formation Bba - Protein Structure. 491: 253-264. PMID 849460 DOI: 10.1016/0005-2795(77)90061-7 |
0.328 |
|
| 1977 |
Lohrmann R, Orgel LE. Template-directed reactions of aminonucleosides Journal of Molecular Evolution. 9: 323-328. PMID 302339 DOI: 10.1007/Bf01796094 |
0.33 |
|
| 1976 |
Osterberg R, Orgel LE, Lohrmann R. Further studies of urea-catalyzed phosphorylation reactions. Journal of Molecular Evolution. 2: 231-4. PMID 4807192 DOI: 10.1007/Bf01654004 |
0.332 |
|
| 1976 |
Verlander MS, Lohrmann R, Orgel LE. Catalysts for the self-polymerization of adenosine cyclic 2', 3'-phosphate. Journal of Molecular Evolution. 2: 303-16. PMID 4377773 DOI: 10.1007/Bf01654098 |
0.309 |
|
| 1976 |
Handschuh GJ, Lohrmann R, Orgel LE. The effect of Mg2+ and Ca2+ on urea-catalyzed phosphorylation reactions. Journal of Molecular Evolution. 2: 251-62. PMID 4377772 DOI: 10.1007/Bf01654094 |
0.335 |
|
| 1976 |
Lohrmann R, Orgel LE. Template directed synthesis of high molecular weight polynucleotide analogues Nature. 261: 342-344. PMID 1272416 DOI: 10.1038/261342A0 |
0.399 |
|
| 1976 |
Gibbs DE, Orgel LE. Triple helices formed by polyuridylic acid with some amino deoxyadenosine derivatives Journal of Molecular Evolution. 8: 55-58. PMID 1084930 DOI: 10.1007/Bf01738882 |
0.324 |
|
| 1976 |
Ehler KW, Orgel LE. N,N′-carbonyldiimidazole-induced peptide formation in aqueous solution Bba - Protein Structure. 434: 233-243. PMID 938667 DOI: 10.1016/0005-2795(76)90055-6 |
0.326 |
|
| 1976 |
Lohrmann R, Orgel LE. Polymerization of nucleotide analogues I: Reaction of nucleoside 5′-phosphorimidazolides with 2′-amino-2′-deoxyuridine Journal of Molecular Evolution. 7: 253-267. PMID 933177 DOI: 10.1007/Bf01743625 |
0.389 |
|
| 1975 |
Fuller WD, Sanchez RA, Orgel LE. Studies in prebiotic synthesis: VII. Solid-state synthesis of purine nucleosides. Journal of Molecular Evolution. 1: 249-57. PMID 4681226 DOI: 10.1007/Bf01660244 |
0.358 |
|
| 1975 |
Osterberg R, Orgel LE. Polyphosphate and trimetaphosphate formation under potentially prebiotic conditions. Journal of Molecular Evolution. 1: 241-8. PMID 4681225 DOI: 10.1007/Bf01660243 |
0.301 |
|
| 1975 |
Lohrmann R, Ranganathan R, Sawai H, Orgel LE. Prebiotic peptide-formation in the solid state. I. Reactions of benzoate ion and glycine with adenosine 5'-phosphorimidazolide. Journal of Molecular Evolution. 5: 57-73. PMID 1177327 DOI: 10.1007/Bf01732014 |
0.313 |
|
| 1975 |
Shim JL, Lohrmann R, Orgel LE. Triple helices formed by polyuridylic acid with some adenosine derivatives Journal of Molecular Evolution. 5: 117-123. PMID 1159798 DOI: 10.1007/Bf01732516 |
0.331 |
|
| 1975 |
Sawai H, Orgel LE. Prebiotic peptide-formation in the solid state - III. Condensation Reactions of Glycine in Solid State Mixtures Containing Inorganic Polyphosphates Journal of Molecular Evolution. 6: 185-197. PMID 1539 DOI: 10.1007/Bf01732355 |
0.305 |
|
| 1975 |
Sawai H, Lohrmann R, Orgel LE. Prebiotic peptide-formation in the solid state - II. Reaction of Glycine with Adenosine 5′-Triphosphate and P1, P2-Diadenosine-Pyrophosphate Journal of Molecular Evolution. 6: 165-184. PMID 1538 DOI: 10.1007/Bf01732354 |
0.326 |
|
| 1975 |
SAWAI H, ORGEL LE. ChemInform Abstract: OLIGONUCLEOTIDE SYNTHESIS CATALYZED BY THE ZN(2+) ION Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197534378 |
0.314 |
|
| 1974 |
Verlander MS, Orgel LE. Analysis of high molecular weight material from the polymerization of adenosine cyclic 2′, 3′-phosphate Journal of Molecular Evolution. 3: 115-120. PMID 4366449 DOI: 10.1007/Bf01796557 |
0.302 |
|
| 1974 |
Orgel LE, Lohrmann R. Prebiotic chemistry and nucleic acid replication Accounts of Chemical Research. 7: 368-377. DOI: 10.1021/Ar50083A002 |
0.379 |
|
| 1973 |
Biebricher CK, Orgel LE. An RNA that multiplies indefinitely with DNA-dependent RNA polymerase: selection from a random copolymer. Proceedings of the National Academy of Sciences of the United States of America. 70: 934-8. PMID 4577140 DOI: 10.1073/Pnas.70.3.934 |
0.317 |
|
| 1973 |
Lohrmann R, Orgel LE. Prebiotic Activation Processes Nature. 244: 418-420. PMID 4355060 DOI: 10.1038/244418A0 |
0.336 |
|
| 1972 |
Fuller WD, Sanchez RA, Orgel LE. Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides. Journal of Molecular Biology. 67: 25-33. PMID 4339529 DOI: 10.1016/0022-2836(72)90383-X |
0.308 |
|
| 1972 |
Renz M, Lohrmann R, Orgel LE. Catalysts for the polymerization of adenosine cyclic 2',3'-phosphate on a poly (U) template. Biochimica Et Biophysica Acta. 240: 463-71. PMID 4330816 DOI: 10.1016/0005-2787(71)90703-9 |
0.317 |
|
| 1972 |
Sanchez RA, Ferris JP, Orgel LE. Studies in prebiotic synthesis. IV. Conversion of 4-aminoimidazole-5-carbonitrile derivatives to purines. Journal of Molecular Biology. 38: 121-8. PMID 4330696 DOI: 10.1016/0022-2836(68)90132-0 |
0.35 |
|
| 1971 |
Chung NM, Lohrmann R, Orgel LE. Template catalysis of acetyl transfer reactions. Biochimica Et Biophysica Acta. 228: 536-43. PMID 5545881 DOI: 10.1016/0005-2787(71)90059-1 |
0.327 |
|
| 1971 |
Lohrmann R, Orgel LE. Urea-inorganic phosphate mixtures as prebiotic phosphorylating agents. Science (New York, N.Y.). 171: 490-4. PMID 5099649 DOI: 10.1126/Science.171.3970.490 |
0.312 |
|
| 1970 |
Schneider-Bernloehr H, Lohrmann R, Sulston J, Orgel LE, Miles HT. Specificity of template-directed synthesis with adenine nucleosides. Journal of Molecular Biology. 47: 257-60. PMID 5434842 DOI: 10.1016/0022-2836(70)90344-X |
0.591 |
|
| 1969 |
Ferris JP, Sanchez RA, Orgel LE. Studies in prebiotic synthesis. 3. Synthesis of pyrimidines from cyanoacetylene and cyanate. Journal of Molecular Biology. 33: 693-704. PMID 5700419 DOI: 10.1016/0022-2836(68)90314-8 |
0.379 |
|
| 1969 |
Sulston J, Lohrmann R, Orgel LE, Schneider-Bernloehr H, Weimann BJ, Miles HT. Non-enzymic oligonucleotide synthesis on a polycytidylate template. Journal of Molecular Biology. 40: 227-34. PMID 5365010 DOI: 10.1016/0022-2836(69)90471-9 |
0.62 |
|
| 1968 |
Schneider-Bernloehr H, Lohrmann R, Orgel LE, Sulston J, Weimann BJ. Partial resolution of DL-adenosine by template synthesis. Science (New York, N.Y.). 162: 809-10. PMID 5686222 DOI: 10.1126/Science.162.3855.809 |
0.589 |
|
| 1968 |
Weimann BJ, Lohrmann R, Orgel LE, Schneider-Bernloehr H, Sulston JE. Template-directed synthesis with adenosine-5'-phosphorimidazolide. Science (New York, N.Y.). 161: 387. PMID 5661298 DOI: 10.1126/Science.161.3839.387 |
0.638 |
|
| 1968 |
Lohrmann R, Orgel LE. Prebiotic synthesis: phosphorylation in aqueous solution. Science (New York, N.Y.). 161: 64-6. PMID 5655266 DOI: 10.1126/Science.161.3836.64 |
0.321 |
|
| 1968 |
Sulston J, Lohrmann R, Orgel LE, Miles HT. Specificity of oligonucleotide synthesis directed by polyuridylic acid. Proceedings of the National Academy of Sciences of the United States of America. 60: 409-15. PMID 5248804 DOI: 10.1073/Pnas.60.2.409 |
0.633 |
|
| 1968 |
Sulston J, Lohrmann R, Orgel LE, Miles HT. Nonenzymatic synthesis of oligoadenylates on a polyuridylic acid template. Proceedings of the National Academy of Sciences of the United States of America. 59: 726-33. PMID 5238657 DOI: 10.1073/Pnas.59.3.726 |
0.633 |
|
| 1968 |
Schneider-Bernloehr H, Lohrmann R, Sulston J, Weimann BJ, Orgel LE, Miles HT. Non-enzymic synthesis of deoxyadenylate oligonucleotides on a polyuridylate template. Journal of Molecular Biology. 37: 151-5. PMID 4329391 DOI: 10.1016/0022-2836(68)90079-X |
0.627 |
|
| 1967 |
Reid C, Orgel LE, Ponnamperuma C. Nucleoside synthesis under potentially prebiotic conditions. Nature. 216: 936. PMID 6074979 DOI: 10.1038/216936A0 |
0.361 |
|
| 1966 |
Sanchez R, Ferris J, Orgel LE. Conditions for purine synthesis: did prebiotic synthesis occur at low temperatures? Science (New York, N.Y.). 153: 72-3. PMID 5938419 DOI: 10.1126/Science.153.3731.72 |
0.323 |
|
| 1966 |
Ferris JP, Orgel LE. Studies on prebiotic synthesis. I. Aminomalononitrile and 4-amino-5-cyanoimidazole. Journal of the American Chemical Society. 88: 3829-31. PMID 5916373 DOI: 10.1021/Ja00968A028 |
0.353 |
|
| 1966 |
Ferris JP, Orgel LE. Aminomalononitrile and 4-amino-5-cyanoimidazole in hydrogen cyanide polymerization and adenine synthesis. Journal of the American Chemical Society. 87: 4976-7. PMID 5844474 DOI: 10.1021/Ja00949A068 |
0.328 |
|
| 1959 |
Bernhard SA, Orgel LE. Mechanism of enzyme inhibition by phosphate esters Science. 130: 625-626. PMID 13799750 DOI: 10.1126/Science.130.3376.625 |
0.626 |
|
| 1957 |
Orgel LE, Mulliken RS. Molecular Complexes and Their Spectra. VII. The Spectrophotometric Study of Molecular Complexes in Solution; Contact Charge-transfer Spectra1 Journal of the American Chemical Society. 79: 4839-4846. DOI: 10.1021/ja01575a006 |
0.414 |
|
| 1957 |
Dunitz J, Orgel L. Electronic properties of transition-metal oxides—I Journal of Physics and Chemistry of Solids. 3: 20-29. DOI: 10.1016/0022-3697(57)90043-4 |
0.523 |
|
| 1957 |
Dunitz J, Orgel L. Electronic properties of transition-metal oxides-II Journal of Physics and Chemistry of Solids. 3: 318-323. DOI: 10.1016/0022-3697(57)90035-5 |
0.518 |
|
| 1956 |
Dunitz JD, Orgel LE. Comments on a method of structure determination Acta Crystallographica. 9: 537-537. DOI: 10.1107/S0365110X56001455 |
0.508 |
|
| 1956 |
Dunitz JD, Orgel LE, Rich A. The crystal structure of ferrocene Acta Crystallographica. 9: 373-375. DOI: 10.1107/S0365110X56001091 |
0.518 |
|
| 1955 |
Dunitz JD, Orgel LE. Electronic Structure of Metal bis‐cyclopentadienyls The Journal of Chemical Physics. 23: 954-958. DOI: 10.1063/1.1742154 |
0.521 |
|
| 1954 |
Craig DP, MacColl A, Nyholm RS, Orgel LE, Sutton LE. Chemical bonds involving d-orbitals. Part II Journal of the Chemical Society (Resumed). 354-357. DOI: 10.1039/JR9540000354 |
0.456 |
|
| 1952 |
Dunitz JD, Orgel LE. Influence of Chain Length on the Symmetry of Conjugated Molecules The Journal of Chemical Physics. 20: 1328-1328. DOI: 10.1063/1.1700736 |
0.527 |
|
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