Anurag Tandon, PhD - Publications

Affiliations: 
Centre for Research in Neurodegenerative Diseases University of Toronto, Toronto, ON, Canada 
Area:
Parkinson's disease

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Menon S, Armstrong S, Hamzeh A, Visanji NP, Sardi SP, Tandon A. Alpha-Synuclein Targeting Therapeutics for Parkinson's Disease and Related Synucleinopathies. Frontiers in Neurology. 13: 852003. PMID 35614915 DOI: 10.3389/fneur.2022.852003  0.449
2020 Chen RHC, Wislet-Gendebien S, Samuel F, Visanji NP, Zhang G, Marsilio D, Langman T, Fraser PE, Tandon A. Correction: α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity. The Journal of Biological Chemistry. 295: 14248. PMID 33037082 DOI: 10.1074/jbc.AAC120.015921  0.512
2020 Wislet-Gendebien S, D'Souza C, Kawarai T, St George-Hyslop P, Westaway D, Fraser P, Tandon A. Withdrawal: Cytosolic proteins regulate α-synuclein dissociation from presynaptic membranes. The Journal of Biological Chemistry. 295: 13694. PMID 32978332 DOI: 10.1074/jbc.W120.015777  0.469
2018 Rodriguez L, Marano MM, Tandon A. Import and Export of Misfolded α-Synuclein. Frontiers in Neuroscience. 12: 344. PMID 29875627 DOI: 10.3389/Fnins.2018.00344  0.313
2018 Lautenschläger J, Stephens AD, Fusco G, Ströhl F, Curry N, Zacharopoulou M, Michel CH, Laine R, Nespovitaya N, Fantham M, Pinotsi D, Zago W, Fraser P, Tandon A, St George-Hyslop P, et al. C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction. Nature Communications. 9: 712. PMID 29459792 DOI: 10.1038/S41467-018-03111-4  0.498
2016 Gómez-Sánchez R, Yakhine-Diop SM, Bravo-San Pedro JM, Pizarro-Estrella E, Rodríguez-Arribas M, Climent V, Martin-Cano FE, González-Soltero ME, Tandon A, Fuentes JM, González-Polo RA. PINK1 deficiency enhances autophagy and mitophagy induction. Molecular & Cellular Oncology. 3: e1046579. PMID 27308585 DOI: 10.1080/23723556.2015.1046579  0.303
2015 Samuel F, Flavin WP, Iqbal S, Pacelli C, Sri Renganathan SD, Trudeau LE, Campbell EM, Fraser PE, Tandon A. Effects of Serine 129 phosphorylation on α-synuclein aggregation, membrane association, and internalization. The Journal of Biological Chemistry. PMID 26719332 DOI: 10.1074/Jbc.M115.705095  0.559
2013 Chen RH, Wislet-Gendebien S, Samuel F, Visanji NP, Zhang G, Marsilio D, Langman T, Fraser PE, Tandon A. α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity. The Journal of Biological Chemistry. 288: 7438-49. PMID 23344955 DOI: 10.1074/Jbc.M112.439497  0.631
2012 Fauvet B, Fares MB, Samuel F, Dikiy I, Tandon A, Eliezer D, Lashuel HA. Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein. The Journal of Biological Chemistry. 287: 28243-62. PMID 22718772 DOI: 10.1074/Jbc.M112.383711  0.566
2011 Visanji NP, Wislet-Gendebien S, Oschipok LW, Zhang G, Aubert I, Fraser PE, Tandon A. Effect of Ser-129 phosphorylation on interaction of α-synuclein with synaptic and cellular membranes. The Journal of Biological Chemistry. 286: 35863-73. PMID 21849493 DOI: 10.1074/Jbc.M111.253450  0.334
2010 Dyllick-Brenzinger M, D'Souza CA, Dahlmann B, Kloetzel PM, Tandon A. Reciprocal effects of alpha-synuclein overexpression and proteasome inhibition in neuronal cells and tissue. Neurotoxicity Research. 17: 215-27. PMID 19653055 DOI: 10.1007/S12640-009-9094-1  0.32
2008 Wislet-Gendebien S, Visanji NP, Whitehead SN, Marsilio D, Hou W, Figeys D, Fraser PE, Bennett SA, Tandon A. Differential regulation of wild-type and mutant alpha-synuclein binding to synaptic membranes by cytosolic factors. Bmc Neuroscience. 9: 92. PMID 18808659 DOI: 10.1186/1471-2202-9-92  0.357
2008 Haque ME, Thomas KJ, D'Souza C, Callaghan S, Kitada T, Slack RS, Fraser P, Cookson MR, Tandon A, Park DS. Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America. 105: 1716-21. PMID 18218782 DOI: 10.1073/Pnas.0705363105  0.301
2006 Wislet-Gendebien S, D'Souza C, Kawarai T, St George-Hyslop P, Westaway D, Fraser P, Tandon A. Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes. The Journal of Biological Chemistry. 281: 32148-55. PMID 16926154 DOI: 10.1074/Jbc.M605965200  0.521
2006 Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, et al. TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 440: 1208-12. PMID 16641999 DOI: 10.1038/Nature04667  0.534
2005 Petit A, Kawarai T, Paitel E, Sanjo N, Maj M, Scheid M, Chen F, Gu Y, Hasegawa H, Salehi-Rad S, Wang L, Rogaeva E, Fraser P, Robinson B, St George-Hyslop P, ... Tandon A, et al. Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. The Journal of Biological Chemistry. 280: 34025-32. PMID 16079129 DOI: 10.1074/Jbc.M505143200  0.46
2004 Rogaeva E, Johnson J, Lang AE, Gulick C, Gwinn-Hardy K, Kawarai T, Sato C, Morgan A, Werner J, Nussbaum R, Petit A, Okun MS, McInerney A, Mandel R, Groen JL, ... ... Tandon A, et al. Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease. Archives of Neurology. 61: 1898-904. PMID 15596610 DOI: 10.1001/Archneur.61.12.1898  0.486
2004 Jo E, Darabie AA, Han K, Tandon A, Fraser PE, McLaurin J. alpha-Synuclein-synaptosomal membrane interactions: implications for fibrillogenesis. European Journal of Biochemistry / Febs. 271: 3180-9. PMID 15265037 DOI: 10.1111/J.1432-1033.2004.04250.X  0.333
2003 Tandon A, Yu H, Wang L, Rogaeva E, Sato C, Chishti MA, Kawarai T, Hasegawa H, Chen F, Davies P, Fraser PE, Westaway D, St George-Hyslop PH. Brain levels of CDK5 activator p25 are not increased in Alzheimer's or other neurodegenerative diseases with neurofibrillary tangles. Journal of Neurochemistry. 86: 572-81. PMID 12859671 DOI: 10.1046/J.1471-4159.2003.01865.X  0.486
2003 Chen F, Tandon A, Sanjo N, Gu YJ, Hasegawa H, Arawaka S, Lee FJ, Ruan X, Mastrangelo P, Erdebil S, Wang L, Westaway D, Mount HT, Yankner B, Fraser PE, et al. Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain. The Journal of Biological Chemistry. 278: 19974-9. PMID 12646573 DOI: 10.1074/Jbc.M210049200  0.535
2003 Gu Y, Chen F, Sanjo N, Kawarai T, Hasegawa H, Duthie M, Li W, Ruan X, Luthra A, Mount HT, Tandon A, Fraser PE, St George-Hyslop P. APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes. The Journal of Biological Chemistry. 278: 7374-80. PMID 12471034 DOI: 10.1074/Jbc.M209499200  0.545
2002 Arawaka S, Hasegawa H, Tandon A, Janus C, Chen F, Yu G, Kikuchi K, Koyama S, Kato T, Fraser PE, St George-Hyslop P. The levels of mature glycosylated nicastrin are regulated and correlate with gamma-secretase processing of amyloid beta-precursor protein. Journal of Neurochemistry. 83: 1065-71. PMID 12437577 DOI: 10.1046/J.1471-4159.2002.01207.X  0.539
2002 Yang DS, Tandon A, Chen F, Yu G, Yu H, Arawaka S, Hasegawa H, Duthie M, Schmidt SD, Ramabhadran TV, Nixon RA, Mathews PM, Gandy SE, Mount HT, St George-Hyslop P, et al. Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins. The Journal of Biological Chemistry. 277: 28135-42. PMID 12032140 DOI: 10.1074/Jbc.M110871200  0.561
2001 Rogaeva E, Tandon A, St George-Hyslop PH. Genetic markers in the diagnosis of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 3: 293-304. PMID 12214050 DOI: 10.3233/Jad-2001-3304  0.498
2001 Chen F, Yu G, Arawaka S, Nishimura M, Kawarai T, Yu H, Tandon A, Supala A, Song YQ, Rogaeva E, Milman P, Sato C, Yu C, Janus C, Lee J, et al. Nicastrin binds to membrane-tethered Notch. Nature Cell Biology. 3: 751-4. PMID 11483961 DOI: 10.1038/35087069  0.546
2000 Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser P, Haass C, et al. Mutation of conserved aspartates affect maturation of presenilin 1 and presenilin 2 complexes. Acta Neurologica Scandinavica. Supplementum. 176: 6-11. PMID 11261807 DOI: 10.1034/J.1600-0404.2000.00301.X  0.507
2000 Zhang DM, Levitan D, Yu G, Nishimura M, Chen F, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Liang Y, Holmes E, Milman P, Sato C, et al. Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans. Neuroreport. 11: 3227-30. PMID 11043553 DOI: 10.1097/00001756-200009280-00035  0.526
2000 Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, et al. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 407: 48-54. PMID 10993067 DOI: 10.1038/35024009  0.516
2000 Tandon A, Rogaeva E, Mullan M, St George-Hyslop PH. Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins. Current Opinion in Neurology. 13: 377-84. PMID 10970053 DOI: 10.1097/00019052-200008000-00003  0.433
2000 Chen F, Yang DS, Petanceska S, Yang A, Tandon A, Yu G, Rozmahel R, Ghiso J, Nishimura M, Zhang DM, Kawarai T, Levesque G, Mills J, Levesque L, Song YQ, et al. Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells. The Journal of Biological Chemistry. 275: 36794-802. PMID 10962005 DOI: 10.1074/Jbc.M006986200  0.551
2000 Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser PE, Haass C, et al. Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes. The Journal of Biological Chemistry. 275: 27348-53. PMID 10856299 DOI: 10.1074/Jbc.M002982200  0.342
2000 Chen F, Yang D, Tandon A, Yu G, Rozmahel R, Nishimura M. 720 proteolytic derivatives of Alzheimer β-amyloid precuesor protein accumulate in restricted and unpredicted intracellular compartments in preseniln 1 deficient cells Neurobiology of Aging. 21: 143. DOI: 10.1016/S0197-4580(00)82445-8  0.308
1996 Tandon A, Bachoo M, Weldon P, Polosa C, Collier B. Effects of colchicine application to preganglionic axons on choline acetyltransferase activity and acetylcholine content and release in the superior cervical ganglion. Journal of Neurochemistry. 66: 1033-41. PMID 8769864 DOI: 10.1046/J.1471-4159.1996.66031033.X  0.392
1996 Schalk I, Zeng K, Wu SK, Stura EA, Matteson J, Huang M, Tandon A, Wilson IA, Balch WE. Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature. 381: 42-8. PMID 8609986 DOI: 10.1038/381042A0  0.305
1995 Tandon A, Collier B. Increased acetylcholine content induced by antidromic stimulation of a sympathetic ganglion: a possible retrograde action of adenosine. Journal of Neurochemistry. 65: 2116-23. PMID 7595497 DOI: 10.1046/J.1471-4159.1995.65052116.X  0.387
1994 Tandon A, Collier B. The role of endogenous adenosine in a poststimulation increase in the acetylcholine content of a sympathetic ganglion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4927-36. PMID 8046461 DOI: 10.1523/Jneurosci.14-08-04927.1994  0.406
1993 Tandon A, Collier B. Increased acetylcholine content induced by adenosine in a sympathetic ganglion and its subsequent mobilization by electrical stimulation. Journal of Neurochemistry. 60: 2124-33. PMID 8492121 DOI: 10.1111/J.1471-4159.1993.Tb03497.X  0.404
1993 Collier B, Tandon A, Prado MA, Bachoo M. Storage and release of acetylcholine in a sympathetic ganglion. Progress in Brain Research. 98: 183-9. PMID 8248507 DOI: 10.1016/S0079-6123(08)62397-3  0.401
1991 Tandon A, Collier B, Zhang ZW, Feltz P. Acetylcholine synthesis in a primary culture of porcine intermediate lobe cells. Journal of Neuroendocrinology. 3: 273-7. PMID 19215464 DOI: 10.1111/J.1365-2826.1991.Tb00275.X  0.38
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