Jonathan C. Makielski - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Physiology Biology, General Biophysics

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Markandeya YS, Gregorich ZR, Feng L, Ramchandran V, O' Hara T, Vaidyanathan R, Mansfield C, Keefe AM, Beglinger CJ, Best JM, Kalscheur MM, Lea MR, Hacker TA, Gorelik J, Trayanova NA, ... ... Makielski JC, et al. Caveolin-3 and Caveolae regulate ventricular repolarization. Journal of Molecular and Cellular Cardiology. PMID 36842733 DOI: 10.1016/j.yjmcc.2023.02.005  0.353
2021 Hu RM, Song EJ, Tester DJ, Deschenes I, Ackerman MJ, Makielski JC, Tan BH. Expression defect of the rare variant/Brugada mutation R1512W depends upon the SCN5A splice variant background and can be rescued by mexiletine and the common polymorphism H558R. Channels (Austin, Tex.). 15: 253-261. PMID 33535892 DOI: 10.1080/19336950.2021.1875645  0.45
2020 Reilly L, Alvarado FJ, Lang D, Abozeid S, Van Ert H, Spellman C, Warden J, Makielski JC, Glukhov AV, Eckhardt LL. Genetic Loss of Causes Adrenergic-Induced Phase 3 Early Afterdepolariz ations and Polymorphic and Bidirectional Ventricular Tachycardia. Circulation. Arrhythmia and Electrophysiology. 13: e008638. PMID 32931337 DOI: 10.1161/Circep.120.008638  0.456
2018 Ramratnam M, Kenny B, Kyle JW, Wiedmeyer B, Hacker TA, Barefield DY, McNally EM, Makielski JC. Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function. Heliyon. 4: e00677. PMID 29998196 DOI: 10.1016/J.Heliyon.2018.E00677  0.432
2018 Hu RM, Tester DJ, Li R, Sun T, Peterson BZ, Ackerman MJ, Makielski JC, Tan BH. Mexiletine rescues a mixed biophysical phenotype of the cardiac sodium channel arising from the SCN5A mutation, N406K, found in LQT3 patients. Channels (Austin, Tex.). PMID 29983085 DOI: 10.1080/19336950.2018.1475794  0.525
2018 Ramratnam M, Linnerooth W, Kyle JW, Weidmeyer BA, Lacount ED, Ahmad N, Pasternak A, McNally EM, Makielski JC. Abstract 427: Inhibition of Myocardial Romk Channels Blocks Ischemic Preconditioning Induced Cardio-protection Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.427  0.409
2017 Cheng J, Kyle JW, Lang D, Wiedmeyer B, Guo J, Yin K, Huang L, Vaidyanathan R, Su T, Makielski JC. An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population. Journal of the American Heart Association. 6. PMID 28373245 DOI: 10.1161/Jaha.116.005330  0.374
2017 Cheng J, Kyle JW, Wiedmeyer B, Lang D, Vaidyanathan R, Makielski JC. Vinculin variant M94I identified in sudden unexplained nocturnal death syndrome decreases cardiac sodium current. Scientific Reports. 7: 42953. PMID 28218286 DOI: 10.1038/Srep42953  0.492
2016 Huang L, Tang S, Chen Y, Zhang L, Yin K, Wu Y, Zheng J, Wu Q, Makielski JC, Cheng J. Molecular pathological study on LRRC10 in sudden unexplained nocturnal death syndrome in the Chinese Han population. International Journal of Legal Medicine. PMID 28032242 DOI: 10.1007/S00414-016-1516-Z  0.369
2016 Zheng J, Zhou F, Su T, Huang L, Wu Y, Yin K, Wu Q, Tang S, Makielski JC, Cheng J. The biophysical characterization of the first SCN5A mutation R1512W identified in Chinese sudden unexplained nocturnal death syndrome. Medicine. 95: e3836. PMID 27281089 DOI: 10.1097/MD.0000000000003836  0.474
2016 Vaidyanathan R, Markandeya YS, Kamp TJ, Makielski JC, Janaury CT, Eckhardt LL. IK1-Enhanced Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: An Improved Cardiomyocyte Model to Investigate Inherited Arrhythmia Syndromes. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00481.2015. PMID 27059077 DOI: 10.1152/Ajpheart.00481.2015  0.369
2016 Makielski JC. Late sodium current: A mechanism for angina, heart failure, and arrhythmia. Trends in Cardiovascular Medicine. 26: 115-22. PMID 26092781 DOI: 10.1016/J.Tcm.2015.05.006  0.384
2016 Cheng J, Kyle JW, Adsit GS, Valdivia CR, Fisher AK, Makielski JC. Cysteine Residues C489 and C1135 of NaV 1.5 Play a Critical Role in Producing Late Sodium Current through nNOS-Dependent S-Nitrosylation of NaV 1.5 Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.652  0.31
2015 Zhao Q, Chen Y, Peng L, Gao R, Liu N, Jiang P, Liu C, Tang S, Quan L, Makielski JC, Cheng J. Identification of rare variants of DSP gene in sudden unexplained nocturnal death syndrome in the southern Chinese Han population. International Journal of Legal Medicine. PMID 26585738 DOI: 10.1007/S00414-015-1275-2  0.329
2015 Makielski JC, Kyle JW. Late I(Na) in the Heart: Physiology, Pathology, and Pathways. Circulation. 132: 553-5. PMID 26187181 DOI: 10.1161/Circulationaha.115.017980  0.45
2015 Yang KC, Kyle JW, Makielski JC, Dudley SC. Mechanisms of sudden cardiac death: oxidants and metabolism. Circulation Research. 116: 1937-55. PMID 26044249 DOI: 10.1161/Circresaha.116.304691  0.444
2015 Hu RM, Tan BH, Tester DJ, Song C, He Y, Dovat S, Peterson BZ, Ackerman MJ, Makielski JC. Arrhythmogenic Biophysical Phenotype for SCN5A Mutation S1787N Depends upon Splice Variant Background and Intracellular Acidosis. Plos One. 10: e0124921. PMID 25923670 DOI: 10.1371/Journal.Pone.0124921  0.454
2015 Kapplinger JD, Giudicessi JR, Ye D, Tester DJ, Callis TE, Valdivia CR, Makielski JC, Wilde AA, Ackerman MJ. Enhanced Classification of Brugada Syndrome- and Long QT Syndrome-Associated Genetic Variants in the SCN5A-Encoded Nav1.5 Cardiac Sodium Channel. Circulation. Cardiovascular Genetics. PMID 25904541 DOI: 10.1161/Circgenetics.114.000831  0.4
2014 Lin EC, Moungey BM, Lim E, Concannon SP, Anderson CL, Kyle JW, Makielski JC, Balijepalli SY, January CT. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function. Journal of the American Heart Association. 3: e001491. PMID 25497881 DOI: 10.1161/Jaha.114.001491  0.525
2014 Kyle JW, Makielski JC. Diseases caused by mutations in Nav1.5 interacting proteins. Cardiac Electrophysiology Clinics. 6: 797-809. PMID 25395996 DOI: 10.1016/J.Ccep.2014.08.007  0.474
2014 Spencer CI, Baba S, Nakamura K, Hua EA, Sears MA, Fu CC, Zhang J, Balijepalli S, Tomoda K, Hayashi Y, Lizarraga P, Wojciak J, Scheinman MM, Aalto-Setälä K, Makielski JC, et al. Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. Stem Cell Reports. 3: 269-81. PMID 25254341 DOI: 10.1016/J.Stemcr.2014.06.003  0.473
2014 Fahrenbach JP, Stoller D, Kim G, Aggarwal N, Yerokun B, Earley JU, Hadhazy M, Shi NQ, Makielski JC, McNally EM. Abcc9 is required for the transition to oxidative metabolism in the newborn heart. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2804-15. PMID 24648545 DOI: 10.1096/Fj.13-244459  0.383
2014 Kalscheur MM, Vaidyanathan R, Orland KM, Abozeid S, Fabry N, Maginot KR, January CT, Makielski JC, Eckhardt LL. KCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 885-94. PMID 24561538 DOI: 10.1016/J.Hrthm.2014.02.015  0.454
2014 Liu C, Tester DJ, Hou Y, Wang W, Lv G, Ackerman MJ, Makielski JC, Cheng J. Is sudden unexplained nocturnal death syndrome in Southern China a cardiac sodium channel dysfunction disorder? Forensic Science International. 236: 38-45. PMID 24529773 DOI: 10.1016/J.Forsciint.2013.12.033  0.495
2014 Latham I, Vaidyanathan R, Kyle JW, Eckhardt LL, Makielski JC. Maturity Of Ips-Cms For Study Of The Cardiac Sodium Channel Complex Heart Rhythm. 11: 2134. DOI: 10.1016/J.Hrthm.2014.09.027  0.464
2014 Vaidyanathan R, Kyle J, Capes DL, Kamp TJ, January CT, Eckhardt LL, Makielski JC. Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (HIPS-CM's): An Expression Model System for Investigating Cardiac Channelopathies Biophysical Journal. 106: 553a. DOI: 10.1016/J.Bpj.2013.11.3078  0.432
2014 Tan B, Hu R, Peterson B, Dovat S, Ackerman MJ, Makielski JC, Song C. Trafficking-Defective Kir6.1 (KATP) Mutations in Sudden Infant Death Syndrome Biophysical Journal. 106: 553a. DOI: 10.1016/J.Bpj.2013.11.3077  0.538
2013 Aggarwal NT, Shi NQ, Makielski JC. ATP-sensitive potassium currents from channels formed by Kir6 and a modified cardiac mitochondrial SUR2 variant. Channels (Austin, Tex.). 7: 493-502. PMID 24037327 DOI: 10.4161/Chan.26181  0.464
2013 Vaidyanathan R, Vega AL, Song C, Zhou Q, Tan BH, Tan B, Berger S, Makielski JC, Eckhardt LL. The interaction of caveolin 3 protein with the potassium inward rectifier channel Kir2.1: physiology and pathology related to long qt syndrome 9 (LQT9). The Journal of Biological Chemistry. 288: 17472-80. PMID 23640888 DOI: 10.1074/Jbc.M112.435370  0.797
2013 Adsit GS, Vaidyanathan R, Galler CM, Kyle JW, Makielski JC. Channelopathies from mutations in the cardiac sodium channel protein complex. Journal of Molecular and Cellular Cardiology. 61: 34-43. PMID 23557754 DOI: 10.1016/J.Yjmcc.2013.03.017  0.54
2013 Cheng J, Valdivia CR, Vaidyanathan R, Balijepalli RC, Ackerman MJ, Makielski JC. Caveolin-3 suppresses late sodium current by inhibiting nNOS-dependent S-nitrosylation of SCN5A. Journal of Molecular and Cellular Cardiology. 61: 102-10. PMID 23541953 DOI: 10.1016/J.Yjmcc.2013.03.013  0.534
2013 Hu RM, Tan BH, Orland KM, Valdivia CR, Peterson A, Pu J, Makielski JC. Digenic inheritance novel mutations in SCN5a and SNTA1 increase late I(Na) contributing to LQT syndrome. American Journal of Physiology. Heart and Circulatory Physiology. 304: H994-H1001. PMID 23376825 DOI: 10.1152/Ajpheart.00705.2012  0.441
2013 Aggarwal NT, Makielski JC. Redox control of cardiac excitability. Antioxidants & Redox Signaling. 18: 432-68. PMID 22897788 DOI: 10.1089/Ars.2011.4234  0.424
2013 Vaidyanathan R, Vega AL, Song C, Zhou Q, Tan B, Berger S, Makielski JC, Eckhardt LL. The interaction of caveolin 3 protein with the potassium inward rectifier channel Kir2.1. PHYSIOLOGY AND PATHOLOGY RELATED TO LONG QT SYNDROME 9 (LQT9). Journal of Biological Chemistry. 288: 28948. DOI: 10.1074/Jbc.A112.435370  0.778
2012 Beyder A, Strege PR, Reyes S, Bernard CE, Terzic A, Makielski J, Ackerman MJ, Farrugia G. Ranolazine decreases mechanosensitivity of the voltage-gated sodium ion channel Na(v)1.5: a novel mechanism of drug action. Circulation. 125: 2698-706. PMID 22565935 DOI: 10.1161/Circulationaha.112.094714  0.44
2012 Vaidyanathan R, Vega AL, Zhou Q, Makielski JC, Eckhardt LL. Mechanism of LQTS9 Associated Mutant, Caveolin3-F97C, Regulation of Kir2.1 Channels Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2941  0.789
2012 Hu R, Tan B, Valdivia C, Orland KM, Peterson A, He Y, Park DJ, Pu J, Makielski JC. Mutations in SNTA1 and SCN5A Interact to Increase Late Sodium Current in a Patient with Syncope Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2878  0.519
2011 Mottram AR, Valdivia CR, Makielski JC. Fatty acids antagonize bupivacaine-induced I(Na) blockade. Clinical Toxicology (Philadelphia, Pa.). 49: 729-33. PMID 21970771 DOI: 10.3109/15563650.2011.613399  0.37
2011 Tester DJ, Tan BH, Medeiros-Domingo A, Song C, Makielski JC, Ackerman MJ. Loss-of-function mutations in the KCNJ8-encoded Kir6.1 K(ATP) channel and sudden infant death syndrome. Circulation. Cardiovascular Genetics. 4: 510-5. PMID 21836131 DOI: 10.1161/Circgenetics.111.960195  0.501
2011 Cheng J, Tester DJ, Tan BH, Valdivia CR, Kroboth S, Ye B, January CT, Ackerman MJ, Makielski JC. The common African American polymorphism SCN5A-S1103Y interacts with mutation SCN5A-R680H to increase late Na current. Physiological Genomics. 43: 461-6. PMID 21385947 DOI: 10.1152/Physiolgenomics.00198.2010  0.438
2011 Cheng J, Makielski JC, Yuan P, Shi N, Zhou F, Ye B, Tan BH, Kroboth S. Sudden unexplained nocturnal death syndrome in Southern China: an epidemiological survey and SCN5A gene screening. The American Journal of Forensic Medicine and Pathology. 32: 359-63. PMID 20110800 DOI: 10.1097/Paf.0B013E3181D03D02  0.317
2011 Makielski JC. GPD1L Mutations and SCN5A Phosphorylation in Brugada Syndrome Journal of Arrhythmia. 27. DOI: 10.4020/Jhrs.27.Sy15_3  0.492
2011 Makielski JC. Functional Abnormality of Sodium Channel Interacting Proteins in Arrhythmogenesis Journal of Arrhythmia. 27. DOI: 10.4020/Jhrs.27.Ss3_1  0.52
2011 Tan B, Song C, Tester DJ, Zhou Q, He Y, Marion RW, McDonald TV, Ackerman MJ, Makielski JC. Arrhythmogenic Biophysical Phenotype for SCN5A Mutation S1787N Depends upon Splice Variant Background and Low pH Biophysical Journal. 100: 423a-424a. DOI: 10.1016/J.Bpj.2010.12.2507  0.509
2011 Makielski JC, Fozzard HA. Ion Channels and Cardiac Arrhythmia in Heart Disease Comprehensive Physiology. 709-740. DOI: 10.1002/Cphy.Cp020119  0.423
2010 Aggarwal NT, Pravdic D, McNally EM, Bosnjak ZJ, Shi NQ, Makielski JC. The mitochondrial bioenergetic phenotype for protection from cardiac ischemia in SUR2 mutant mice. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1884-90. PMID 20935152 DOI: 10.1152/Ajpheart.00363.2010  0.312
2010 Stoller DA, Fahrenbach JP, Chalupsky K, Tan BH, Aggarwal N, Metcalfe J, Hadhazy M, Shi NQ, Makielski JC, McNally EM. Cardiomyocyte sulfonylurea receptor 2-KATP channel mediates cardioprotection and ST segment elevation. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1100-8. PMID 20656890 DOI: 10.1152/Ajpheart.00084.2010  0.464
2010 Medeiros-Domingo A, Tan BH, Crotti L, Tester DJ, Eckhardt L, Cuoretti A, Kroboth SL, Song C, Zhou Q, Kopp D, Schwartz PJ, Makielski JC, Ackerman MJ. Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 1466-71. PMID 20558321 DOI: 10.1016/J.Hrthm.2010.06.016  0.529
2010 Tester DJ, Valdivia C, Harris-Kerr C, Alders M, Salisbury BA, Wilde AA, Makielski JC, Ackerman MJ. Epidemiologic, molecular, and functional evidence suggest A572D-SCN5A should not be considered an independent LQT3-susceptibility mutation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 912-9. PMID 20403459 DOI: 10.1016/J.Hrthm.2010.04.014  0.44
2010 Tan BH, Pundi KN, Van Norstrand DW, Valdivia CR, Tester DJ, Medeiros-Domingo A, Makielski JC, Ackerman MJ. Sudden infant death syndrome-associated mutations in the sodium channel beta subunits. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 771-8. PMID 20226894 DOI: 10.1016/J.Hrthm.2010.01.032  0.461
2010 Valdivia CR, Medeiros-Domingo A, Ye B, Shen WK, Algiers TJ, Ackerman MJ, Makielski JC. Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillation. Cardiovascular Research. 86: 392-400. PMID 20042427 DOI: 10.1093/Cvr/Cvp417  0.564
2010 Aggarwal N, Pravdic D, Mcnally EM, Bosnjak ZJ, Shi N, Makielski JC. The Mitochondrial Bioenergetic Phenotype for Protection from Ischemia in Sur2-Mutant Mice Biophysical Journal. 98: 412a. DOI: 10.1016/J.Bpj.2009.12.2222  0.322
2009 Cheng J, Van Norstrand DW, Medeiros-Domingo A, Valdivia C, Tan BH, Ye B, Kroboth S, Vatta M, Tester DJ, January CT, Makielski JC, Ackerman MJ. Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current. Circulation. Arrhythmia and Electrophysiology. 2: 667-76. PMID 20009079 DOI: 10.1161/Circep.109.891440  0.49
2009 Rajamani S, El-Bizri N, Shryock JC, Makielski JC, Belardinelli L. Use-dependent block of cardiac late Na(+) current by ranolazine. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 1625-31. PMID 19879541 DOI: 10.1016/J.Hrthm.2009.07.042  0.434
2009 Vega AL, Tester DJ, Ackerman MJ, Makielski JC. Protein kinase A-dependent biophysical phenotype for V227F-KCNJ2 mutation in catecholaminergic polymorphic ventricular tachycardia. Circulation. Arrhythmia and Electrophysiology. 2: 540-7. PMID 19843922 DOI: 10.1161/Circep.109.872309  0.779
2009 Ye B, Kroboth SL, Pu JL, Sims JJ, Aggarwal NT, McNally EM, Makielski JC, Shi NQ. Molecular identification and functional characterization of a mitochondrial sulfonylurea receptor 2 splice variant generated by intraexonic splicing. Circulation Research. 105: 1083-93. PMID 19797704 DOI: 10.1161/Circresaha.109.195040  0.463
2009 Valdivia CR, Ueda K, Ackerman MJ, Makielski JC. GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1446-52. PMID 19666841 DOI: 10.1152/Ajpheart.00513.2009  0.546
2009 Medeiros-Domingo A, Tan BH, Iturralde-Torres P, Tester DJ, Tusié-Luna T, Makielski JC, Ackerman MJ. Unique mixed phenotype and unexpected functional effect revealed by novel compound heterozygosity mutations involving SCN5A. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 1170-5. PMID 19632629 DOI: 10.1016/J.Hrthm.2009.04.034  0.497
2009 Tsurugi T, Nagatomo T, Abe H, Oginosawa Y, Takemasa H, Kohno R, Makita N, Makielski JC, Otsuji Y. Differential modulation of late sodium current by protein kinase A in R1623Q mutant of LQT3. Life Sciences. 84: 380-7. PMID 19167409 DOI: 10.1016/J.Lfs.2009.01.001  0.432
2009 Saito YA, Strege PR, Tester DJ, Locke GR, Talley NJ, Bernard CE, Rae JL, Makielski JC, Ackerman MJ, Farrugia G. Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G211-8. PMID 19056759 DOI: 10.1152/Ajpgi.90571.2008  0.513
2009 Vega A, Eckhardt LL, Makielski JC. Long Qt Syndrome Mutations In Caveolin-3 Cause Loss Of The Kir2.1-mediated Inward Rectifier Potassium Current (iK1) Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2381  0.817
2009 Tan B, Medeiros A, Iturralde P, Ackerman MJ, Makielski JC. SCN5A Missense Mutation from a Patient with Complex Cardiac Rhythm and Conduction Disorder Requires the Common Polymorphism H558R on the Same Allele for Arrhythmogenic Biophysical Phenotype Biophysical Journal. 96: 249. DOI: 10.1016/J.Bpj.2008.12.1228  0.531
2008 Ueda K, Valdivia C, Medeiros-Domingo A, Tester DJ, Vatta M, Farrugia G, Ackerman MJ, Makielski JC. Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex. Proceedings of the National Academy of Sciences of the United States of America. 105: 9355-60. PMID 18591664 DOI: 10.1073/Pnas.0801294105  0.565
2008 Mazzone A, Strege PR, Tester DJ, Bernard CE, Faulkner G, De Giorgio R, Makielski JC, Stanghellini V, Gibbons SJ, Ackerman MJ, Farrugia G. A mutation in telethonin alters Nav1.5 function. The Journal of Biological Chemistry. 283: 16537-44. PMID 18408010 DOI: 10.1074/Jbc.M801744200  0.581
2008 El Yaman M, Perry J, Makielski JC, Ackerman MJ. Suppression of atrial fibrillation with mexiletine pharmacotherapy in a young woman with type 1 long QT syndrome. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 5: 472-4. PMID 18313609 DOI: 10.1016/J.Hrthm.2007.10.029  0.453
2008 Pu JL, Ye B, Kroboth SL, McNally EM, Makielski JC, Shi NQ. Cardiac sulfonylurea receptor short form-based channels confer a glibenclamide-insensitive KATP activity. Journal of Molecular and Cellular Cardiology. 44: 188-200. PMID 18001767 DOI: 10.1016/J.Yjmcc.2007.09.010  0.498
2007 Lehnart SE, Ackerman MJ, Benson DW, Brugada R, Clancy CE, Donahue JK, George AL, Grant AO, Groft SC, January CT, Lathrop DA, Lederer WJ, Makielski JC, Mohler PJ, Moss A, et al. Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation. 116: 2325-45. PMID 17998470 DOI: 10.1161/Circulationaha.107.711689  0.438
2007 Van Norstrand DW, Valdivia CR, Tester DJ, Ueda K, London B, Makielski JC, Ackerman MJ. Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome. Circulation. 116: 2253-9. PMID 17967976 DOI: 10.1161/Circulationaha.107.704627  0.413
2007 Tan BH, Iturralde-Torres P, Medeiros-Domingo A, Nava S, Tester DJ, Valdivia CR, Tusié-Luna T, Ackerman MJ, Makielski JC. A novel C-terminal truncation SCN5A mutation from a patient with sick sinus syndrome, conduction disorder and ventricular tachycardia. Cardiovascular Research. 76: 409-17. PMID 17897635 DOI: 10.1016/J.Cardiores.2007.08.006  0.467
2007 Stoller D, Kakkar R, Smelley M, Chalupsky K, Earley JU, Shi NQ, Makielski JC, McNally EM. Mice lacking sulfonylurea receptor 2 (SUR2) ATP-sensitive potassium channels are resistant to acute cardiovascular stress. Journal of Molecular and Cellular Cardiology. 43: 445-54. PMID 17765261 DOI: 10.1016/J.Yjmcc.2007.07.058  0.383
2007 Medeiros-Domingo A, Kaku T, Tester DJ, Iturralde-Torres P, Itty A, Ye B, Valdivia C, Ueda K, Canizales-Quinteros S, Tusié-Luna MT, Makielski JC, Ackerman MJ. SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome. Circulation. 116: 134-42. PMID 17592081 DOI: 10.1161/Circulationaha.106.659086  0.561
2007 Eckhardt LL, Farley AL, Rodriguez E, Ruwaldt K, Hammill D, Tester DJ, Ackerman MJ, Makielski JC. KCNJ2 mutations in arrhythmia patients referred for LQT testing: a mutation T305A with novel effect on rectification properties. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 4: 323-9. PMID 17341397 DOI: 10.1016/J.Hrthm.2006.10.025  0.42
2007 Cronk LB, Ye B, Kaku T, Tester DJ, Vatta M, Makielski JC, Ackerman MJ. Novel mechanism for sudden infant death syndrome: persistent late sodium current secondary to mutations in caveolin-3. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 4: 161-6. PMID 17275750 DOI: 10.1016/J.Hrthm.2006.11.030  0.418
2007 Zeng Z, Tan C, Teng S, Chen J, Su S, Zhou X, Wang F, Zhang S, Gu D, Makielski JC, Pu J. The single nucleotide polymorphisms of I(Ks) potassium channel genes and their association with atrial fibrillation in a Chinese population. Cardiology. 108: 97-103. PMID 17016049 DOI: 10.1159/000095943  0.476
2006 Vatta M, Ackerman MJ, Ye B, Makielski JC, Ughanze EE, Taylor EW, Tester DJ, Balijepalli RC, Foell JD, Li Z, Kamp TJ, Towbin JA. Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome. Circulation. 114: 2104-12. PMID 17060380 DOI: 10.1161/Circulationaha.106.635268  0.57
2006 Rajamani S, Eckhardt LL, Valdivia CR, Klemens CA, Gillman BM, Anderson CL, Holzem KM, Delisle BP, Anson BD, Makielski JC, January CT. Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine. British Journal of Pharmacology. 149: 481-9. PMID 16967046 DOI: 10.1038/Sj.Bjp.0706892  0.536
2006 Tester DJ, Arya P, Will M, Haglund CM, Farley AL, Makielski JC, Ackerman MJ. Genotypic heterogeneity and phenotypic mimicry among unrelated patients referred for catecholaminergic polymorphic ventricular tachycardia genetic testing. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 3: 800-5. PMID 16818210 DOI: 10.1016/J.Hrthm.2006.03.025  0.455
2006 Makielski JC, Farley AL. Na(+) current in human ventricle: implications for sodium loading and homeostasis. Journal of Cardiovascular Electrophysiology. 17: S15-S20. PMID 16686671 DOI: 10.1111/j.1540-8167.2006.00380.x  0.364
2006 Tan BH, Valdivia CR, Song C, Makielski JC. Partial expression defect for the SCN5A missense mutation G1406R depends on splice variant background Q1077 and rescue by mexiletine. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1822-8. PMID 16632547 DOI: 10.1152/Ajpheart.00101.2006  0.538
2006 Makielski JC, Valdivia CR. Ranolazine and late cardiac sodium current--a therapeutic target for angina, arrhythmia and more? British Journal of Pharmacology. 148: 4-6. PMID 16520741 DOI: 10.1038/Sj.Bjp.0706713  0.461
2006 Kakkar R, Ye B, Stoller DA, Smelley M, Shi NQ, Galles K, Hadhazy M, Makielski JC, McNally EM. Spontaneous coronary vasospasm in KATP mutant mice arises from a smooth muscle-extrinsic process. Circulation Research. 98: 682-9. PMID 16456098 DOI: 10.1161/01.Res.0000207498.40005.E7  0.334
2006 Makielski JC. SIDS: genetic and environmental influences may cause arrhythmia in this silent killer. The Journal of Clinical Investigation. 116: 297-9. PMID 16453014 DOI: 10.1172/Jci27689  0.494
2006 Rajamani S, Anderson CL, Valdivia CR, Eckhardt LL, Foell JD, Robertson GA, Kamp TJ, Makielski JC, Anson BD, January CT. Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr). American Journal of Physiology. Heart and Circulatory Physiology. 290: H1278-88. PMID 16227340 DOI: 10.1152/Ajpheart.00777.2005  0.526
2005 Shi NQ, Ye B, Makielski JC. Function and distribution of the SUR isoforms and splice variants. Journal of Molecular and Cellular Cardiology. 39: 51-60. PMID 15978902 DOI: 10.1016/J.Yjmcc.2004.11.024  0.443
2005 Adamson PB, Barr RC, Callans DJ, Chen PS, Lathrop DA, Makielski JC, Nerbonne JM, Nuss HB, Olgin JE, Przywara DA, Rosen MR, Rozanski GJ, Spach MS, Yamada KA. The perplexing complexity of cardiac arrhythmias: beyond electrical remodeling. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 2: 650-9. PMID 15922277 DOI: 10.1016/J.Hrthm.2005.03.009  0.365
2005 Makielski JC, Valdivia CR. Arrhythmia mutations in non-coding region of SCN5A: implications for genetic screening. Journal of Molecular and Cellular Cardiology. 38: 551-3. PMID 15808831 DOI: 10.1016/J.Yjmcc.2005.01.013  0.323
2005 Kikuchi K, Nagatomo T, Abe H, Kawakami K, Duff HJ, Makielski JC, January CT, Nakashima Y. Blockade of HERG cardiac K+ current by antifungal drug miconazole. British Journal of Pharmacology. 144: 840-8. PMID 15778703 DOI: 10.1038/Sj.Bjp.0706095  0.541
2005 Valdivia CR, Chu WW, Pu J, Foell JD, Haworth RA, Wolff MR, Kamp TJ, Makielski JC. Increased late sodium current in myocytes from a canine heart failure model and from failing human heart. Journal of Molecular and Cellular Cardiology. 38: 475-83. PMID 15733907 DOI: 10.1016/J.Yjmcc.2004.12.012  0.386
2005 Oginosawa Y, Nagatomo T, Abe H, Makita N, Makielski JC, Nakashima Y. Intrinsic mechanism of the enhanced rate-dependent QT shortening in the R1623Q mutant of the LQT3 syndrome. Cardiovascular Research. 65: 138-47. PMID 15621041 DOI: 10.1016/J.Cardiores.2004.09.025  0.54
2005 Tan B, Valdivia CR, Makielski JC. The Brugada syndrome SCN5A mutation G1406R expression defect depends upon splice variant background Q1077 and is rescued by mexiletine Heart Rhythm. 2. DOI: 10.1016/J.Hrthm.2005.02.426  0.397
2005 Valdivia CR, Ruwaldt KM, Makielski JC. Trafficking defective SCN5A Brugada syndrome mutations rescue by different Class I antiarrhythmic drugs Heart Rhythm. 2. DOI: 10.1016/J.Hrthm.2005.02.425  0.365
2005 Ye B, Shi N, Foell J, Balijepalli RC, Kamp TJ, Makielski JC. Role of caveolar lipid rafts in pacemaker channel kinetics Heart Rhythm. 2: S34-S35. DOI: 10.1016/J.Hrthm.2005.02.117  0.395
2004 Ackerman MJ, Splawski I, Makielski JC, Tester DJ, Will ML, Timothy KW, Keating MT, Jones G, Chadha M, Burrow CR, Stephens JC, Xu C, Judson R, Curran ME. Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 1: 600-7. PMID 15851227 DOI: 10.1016/J.Hrthm.2004.07.013  0.51
2004 Tester DJ, Spoon DB, Valdivia HH, Makielski JC, Ackerman MJ. Targeted mutational analysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: a molecular autopsy of 49 medical examiner/coroner's cases. Mayo Clinic Proceedings. 79: 1380-4. PMID 15544015 DOI: 10.4065/79.11.1380  0.448
2004 Valdivia CR, Tester DJ, Rok BA, Porter CB, Munger TM, Jahangir A, Makielski JC, Ackerman MJ. A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs. Cardiovascular Research. 62: 53-62. PMID 15023552 DOI: 10.1016/J.Cardiores.2004.01.022  0.516
2004 Makielski JC, Ye B, Kamp TJ, January CT. Pharmacology of the Cardiac Sodium Channel Cardiac Electrophysiology: Fourth Edition. 127-132. DOI: 10.1016/B0-7216-0323-8/50018-X  0.41
2003 Makielski JC, Ye B, Valdivia CR, Pagel MD, Pu J, Tester DJ, Ackerman MJ. A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels. Circulation Research. 93: 821-8. PMID 14500339 DOI: 10.1161/01.Res.0000096652.14509.96  0.46
2003 Ye B, Valdivia CR, Ackerman MJ, Makielski JC. A common human SCN5A polymorphism modifies expression of an arrhythmia causing mutation. Physiological Genomics. 12: 187-93. PMID 12454206 DOI: 10.1152/Physiolgenomics.00117.2002  0.473
2003 Ou Y, Strege P, Miller SM, Makielski J, Ackerman M, Gibbons SJ, Farrugia G. Syntrophin γ2 Regulates SCN5A Gating by a PDZ Domain-mediated Interaction Journal of Biological Chemistry. 278: 1915-1923. PMID 12429735 DOI: 10.1074/Jbc.M209938200  0.419
2002 Valdivia CR, Nagatomo T, Makielski JC. Late Na currents affected by alpha subunit isoform and beta1 subunit co-expression in HEK293 cells. Journal of Molecular and Cellular Cardiology. 34: 1029-39. PMID 12234772 DOI: 10.1006/Jmcc.2002.2040  0.378
2002 Mbai M, Rajamani S, Delisle BP, Anson BD, Anderson C, Makielski JC, January CT. Genetic basis for the origin of cardiac arrhythmias: implications for therapy. Current Cardiology Reports. 4: 411-7. PMID 12169238 DOI: 10.1007/S11886-002-0041-5  0.328
2002 Valdivia CR, Ackerman MJ, Tester DJ, Wada T, McCormack J, Ye B, Makielski JC. A novel SCN5A arrhythmia mutation, M1766L, with expression defect rescued by mexiletine. Cardiovascular Research. 55: 279-89. PMID 12123767 DOI: 10.1016/S0008-6363(02)00445-5  0.538
2002 Chutkow WA, Pu J, Wheeler MT, Wada T, Makielski JC, Burant CF, McNally EM. Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels. The Journal of Clinical Investigation. 110: 203-8. PMID 12122112 DOI: 10.1172/Jci15672  0.407
2002 Nagatomo T, January CT, Ye B, Abe H, Nakashima Y, Makielski JC. Rate-dependent QT shortening mechanism for the LQT3 deltaKPQ mutant. Cardiovascular Research. 54: 624-9. PMID 12031708 DOI: 10.1016/S0008-6363(02)00265-1  0.528
2001 Ackerman MJ, Siu BL, Sturner WQ, Tester DJ, Valdivia CR, Makielski JC, Towbin JA. Postmortem molecular analysis of SCN5A defects in sudden infant death syndrome. Jama. 286: 2264-2269. PMID 11710892 DOI: 10.1001/Jama.286.18.2264  0.538
2000 Hanck DA, Makielski JC, Sheets MF. Lidocaine alters activation gating of cardiac Na channels. PflüGers Archiv : European Journal of Physiology. 439: 814-21. PMID 10784357 DOI: 10.1007/S004249900217  0.506
2000 Makielski JC, Kamp TJ, Valdivia CR. Oita International Electrocardiology Symposium 2000 “Electrophysiology and Management of Lethal Arrhythmias in the New Millennium: From Genes to Bedside” Japanese Journal of Electrocardiology. 20: 99-100. DOI: 10.5105/Jse.20.Suppl3_99  0.444
1999 Makielski JC, Limberis J, Fan Z, Kyle JW. Intrinsic lidocaine affinity for Na channels expressed in Xenopus oocytes depends on α (hH1 vs. rSkM1) and β1 subunits Cardiovascular Research. 42: 503-509. PMID 10533585 DOI: 10.1016/S0008-6363(99)00024-3  0.383
1999 Fan Z, Makielski JC. Phosphoinositides Decrease Atp Sensitivity of the Cardiac Atp-Sensitive K+ Channel: A Molecular Probe for the Mechanism of Atp-Sensitive Inhibition The Journal of General Physiology. 114: 251-269. PMID 10436001 DOI: 10.1085/Jgp.114.2.251  0.416
1999 Zhang S, Zhou Z, Gong Q, Makielski JC, January CT. Mechanism of block and identification of the verapamil binding domain to HERG potassium channels Circulation Research. 84: 989-998. PMID 10325236 DOI: 10.1161/01.Res.84.9.989  0.541
1999 Chutkow WA, Makielski JC, Nelson DJ, Burant CF, Fan Z. Alternative Splicing of sur2 Exon 17 Regulates Nucleotide Sensitivity of the ATP-sensitive Potassium Channel Journal of Biological Chemistry. 274: 13656-13665. PMID 10224138 DOI: 10.1074/Jbc.274.19.13656  0.451
1998 Nagatomo T, Fan Z, Ye B, Tonkovich GS, January CT, Kyle JW, Makielski JC. Temperature dependence of early and late currents in human cardiac wild-type and long Q-T ΔKPQ Nachannels. American Journal of Physiology. Heart and Circulatory Physiology. 275: H2016-H2024. PMID 29586760 DOI: 10.1152/ajpheart.1998.275.6.H2016  0.339
1998 Nagatomo T, Fan Z, Ye B, Tonkovich GS, January CT, Kyle JW, Makielski JC. Temperature dependence of early and late currents in human cardiac wild- type and long Q-T ΔKPQ Na+ channels American Journal of Physiology - Heart and Circulatory Physiology. 275. PMID 9843800 DOI: 10.1152/Ajpheart.1998.275.6.H2016  0.485
1998 Zhou Z, Gong Q, Ye B, Fan Z, Makielski JC, Robertson GA, January CT. Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature. Biophysical Journal. 74: 230-41. PMID 9449325 DOI: 10.1016/S0006-3495(98)77782-3  0.477
1997 Fan Z, Makielski JC. Anionic Phospholipids Activate ATP-sensitive Potassium Channels Journal of Biological Chemistry. 272: 5388-5395. PMID 9038137 DOI: 10.1074/Jbc.272.9.5388  0.436
1996 Makielski JC. The heart sodium channel phenotype for inactivation and lidocaine block. Japanese Heart Journal. 37: 733-739. PMID 8973385 DOI: 10.1536/Ihj.37.733  0.514
1996 Fan Z, George AL, Kyle JW, Makielski JC. Two Human Paramyotonia Congenita Mutations Have Opposite Effects On Lidocaine Block Of Na+ Channels Expressed In A Mammalian Cell Line The Journal of Physiology. 496: 275-286. PMID 8910215 DOI: 10.1113/Jphysiol.1996.Sp021684  0.503
1996 Undrovinas AI, Makielski JC. Blockade of lysophosphatidylcholine-modified cardiac Na channels by a lidocaine derivative QX-222. The American Journal of Physiology. 271: H790-7. PMID 8770124 DOI: 10.1152/AJPHEART.1996.271.2.H790  0.402
1996 Shander GS, Undrovinas AI, Makielski JC. Rapid Onset Of Lysophosphatidylcholine-Induced Modification Of Whole Cell Cardiac Sodium Current Kinetics Journal of Molecular and Cellular Cardiology. 28: 743-753. PMID 8732502 DOI: 10.1006/Jmcc.1996.0069  0.413
1996 Tokuyama Y, Fan Z, Furuta H, Makielski JC, Polonsky KS, Bell GI, Yano H. Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochemical and Biophysical Research Communications. 220: 532-8. PMID 8607800 DOI: 10.1006/Bbrc.1996.0439  0.378
1995 Shander GS, Fan Z, Makielski JC. Slowly Recovering Cardiac Sodium Current in Rat Ventricular Myocytes: Effects of Conditioning Duration and Recovery Potential Journal of Cardiovascular Electrophysiology. 6: 786-795. PMID 8542075 DOI: 10.1111/J.1540-8167.1995.Tb00355.X  0.395
1995 Undrovinas AI, Shander GS, Makielski JC. Cytoskeleton modulates gating of voltage-dependent sodium channel in heart. The American Journal of Physiology. 269: H203-14. PMID 7631850 DOI: 10.1152/AJPHEART.1995.269.1.H203  0.399
1994 Hanck DA, Makielski JC, Sheets MF. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. The Journal of General Physiology. 103: 19-43. PMID 8169596 DOI: 10.1085/Jgp.103.1.19  0.5
1994 Satin J, Kyle JW, Fan Z, Rogart R, Fozzard HA, Makielski JC. Post-repolarization block of cloned sodium channels by saxitoxin: the contribution of pore-region amino acids Biophysical Journal. 66: 1353-1363. PMID 8061191 DOI: 10.1016/S0006-3495(94)80926-9  0.489
1994 Holevinsky KO, Fan Z, Frame M, Makielski JC, Groppi V, Nelson DJ. ATP-sensitive K+ channel opener acts as a potent Cl- channel inhibitor in vascular smooth muscle cells. The Journal of Membrane Biology. 137: 59-70. PMID 8006946 DOI: 10.1007/Bf00234998  0.455
1994 Fan Z, Tokuyama Y, Makielski JC. Modulation of ATP-sensitive K+ channels by internal acidification in insulin-secreting cells. The American Journal of Physiology. 267: C1036-44. PMID 7943266 DOI: 10.1152/Ajpcell.1994.267.4.C1036  0.392
1993 Fan Z, Makielski JC. Intracellular H+ and Ca2+ modulation of trypsin-modified ATP-sensitive K+ channels in rabbit ventricular myocytes. Circulation Research. 72: 715-722. PMID 8381726 DOI: 10.1161/01.Res.72.3.715  0.395
1993 Makielski JC, Satin J, Fan Z. Post-repolarization block of cardiac sodium channels by saxitoxin Biophysical Journal. 65: 790-798. PMID 8218903 DOI: 10.1016/S0006-3495(93)81102-0  0.331
1993 Fan Z, Furukawa T, Sawanobori T, Makielski JC, Hiraoka M. Cytoplasmic acidosis induces multiple conductance states in ATP-sensitive potassium channels of cardiac myocytes. The Journal of Membrane Biology. 136: 169-79. PMID 8107073 DOI: 10.1007/Bf02505761  0.439
1992 Undrovinas AI, Fleidervish IA, Makielski JC. Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine. Circulation Research. 71: 1231-41. PMID 1327577 DOI: 10.1161/01.Res.71.5.1231  0.513
1991 Nesterenko VV, Anyukhovsky EP, Starmer CF, Beloshapko GG, Ivanovoch T, Makielski JC, Bugrij EM, Mazaev AV, Rosenshtraukh LV. Modulating intraventricular conduction through competition of two class 1 antiarrhythmic agents: experience with ethacizin and lidocaine in canine heart. Journal of Molecular and Cellular Cardiology. 23: 115-124. PMID 2038072 DOI: 10.1016/0022-2828(91)90030-P  0.323
1991 Makielski JC, Falleroni MJ. Temperature dependence of sodium current block by lidocaine in cardiac Purkinje cells. American Journal of Physiology-Heart and Circulatory Physiology. 260. PMID 2000964 DOI: 10.1152/Ajpheart.1991.260.3.H681  0.316
1991 Nelson WL, Makielski JC. Block of sodium current by heptanol in voltage-clamped canine cardiac Purkinje cells. Circulation Research. 68: 977-983. PMID 1849060 DOI: 10.1161/01.Res.68.4.977  0.4
1991 January CT, Chau V, Makielski JC. Triggered activity in the heart: cellular mechanisms of early after-depolarizations. European Heart Journal. 12: 4-9. PMID 1725155  0.366
1991 Makielski JC, Alpert LA, Hanck DA. Two components of use-dependent block of sodium current by lidocaine in voltage clamped cardiac Purkinje cells Journal of Molecular and Cellular Cardiology. 23: 95-102. PMID 1645416 DOI: 10.1016/0022-2828(91)90028-K  0.406
1991 Baumgarten CM, Makielski JC, Fozzard HA. External site for local anesthetic block of cardiac Na+ channels. Journal of Molecular and Cellular Cardiology. 23: 85-93. PMID 1645415 DOI: 10.1016/0022-2828(91)90027-J  0.503
1991 Burnashev NA, Undrovinas AI, Fleidervish IA, Makielski JC, Rosenshtraukh LV. Modulation of cardiac sodium channel gating by lysophosphatidylcholine. Journal of Molecular and Cellular Cardiology. 23: 23-30. PMID 1645412 DOI: 10.1016/0022-2828(91)90020-M  0.487
1990 Undrovinas AI, Burnashev N, Eroshenko D, Fleidervish I, Starmer CF, Makielski JC, Rosenshtraukh LV. Quinidine blocks adenosine 5'-triphosphate-sensitive potassium channels in heart. The American Journal of Physiology. 259: H1609-12. PMID 2240258 DOI: 10.1152/Ajpheart.1990.259.5.H1609  0.468
1989 Alpert LA, Fozzard HA, Hanck DA, Makielski JC. Is there a second external lidocaine binding site on mammalian cardiac cells? American Journal of Physiology - Heart and Circulatory Physiology. 257. PMID 2546451 DOI: 10.1152/Ajpheart.1989.257.1.H79  0.453
1988 Makielski JC, Undrovinas AI, Hanck DA, Sheets MF, Nesterenko VV, Alpert LA, Rosenshtraukh LV, Fozzard HA. Use-dependent block of sodium current by ethmozin in voltage-clamped internally perfused canine cardiac Purkinje cells. Journal of Molecular and Cellular Cardiology. 20: 255-65. PMID 2456399 DOI: 10.1016/S0022-2828(88)80058-0  0.432
1987 Makielski JC, Sheets MF, Hanck DA, January CT, Fozzard HA. Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells. Biophysical Journal. 52: 1-11. PMID 3607218 DOI: 10.1016/S0006-3495(87)83182-X  0.446
1987 Fozzard HA, Hanck DA, Makielski JC, Scanley BE, Sheets MF. Sodium channels in cardiac Purkinje cells. Experientia. 43: 1162-8. PMID 2446909 DOI: 10.1007/Bf01945516  0.494
1987 Brill DM, Fozzard HA, Makielski JC, Wasserstrom JA. Effect of prolonged depolarizations on twitch tension and intracellular sodium activity in sheep cardiac Purkinje fibres. The Journal of Physiology. 384: 355-75. PMID 2443661 DOI: 10.1113/Jphysiol.1987.Sp016459  0.327
1987 Sheets MF, Scanley BE, Hanck DA, Makielski JC, Fozzard HA. Open sodium channel properties of single canine cardiac Purkinje cells. Biophysical Journal. 52: 13-22. PMID 2440490 DOI: 10.1016/S0006-3495(87)83183-1  0.502
1986 Fozzard HA, Friedlander IR, Hanck DA, January CT, Makielski JC, Sheets MF. Sodium currents in single cardiac Purkinje cells. Journal of the American College of Cardiology. 8: 79A-85A. PMID 2423574 DOI: 10.1016/S0735-1097(86)80033-X  0.43
1985 Fozzard HA, January CT, Makielski JC. New studies of the excitatory sodium currents in heart muscle Circulation Research. 56: 475-485. PMID 2579746 DOI: 10.1161/01.Res.56.4.475  0.524
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