Vera Gorbunova - Publications

Affiliations: 
Biology University of Rochester, Rochester, NY 
Area:
Biochemistry, Molecular Biology, Cell Biology, Oncology
Website:
https://www.sas.rochester.edu/bio/people/faculty/gorbunova_vera/

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Romanenko SA, Kliver SF, Serdyukova NA, Perelman PL, Trifonov VA, Seluanov A, Gorbunova V, Azpurua J, Pereira JC, Ferguson-Smith MA, Graphodatsky AS. Integration of fluorescence in situ hybridization and chromosome-length genome assemblies revealed synteny map for guinea pig, naked mole-rat, and human. Scientific Reports. 13: 21055. PMID 38030702 DOI: 10.1038/s41598-023-46595-x  0.722
2023 Zhang Z, Tian X, Lu JY, Boit K, Ablaeva J, Zakusilo FT, Emmrich S, Firsanov D, Rydkina E, Biashad SA, Lu Q, Tyshkovskiy A, Gladyshev VN, Horvath S, Seluanov A, ... Gorbunova V, et al. Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice. Nature. PMID 37612507 DOI: 10.1038/s41586-023-06463-0  0.665
2023 Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, ... ... Gorbunova V, et al. DNA methylation networks underlying mammalian traits. Science (New York, N.Y.). 381: eabq5693. PMID 37561875 DOI: 10.1126/science.abq5693  0.311
2023 Zhao Y, Zheng Z, Zhang Z, Hillpot E, Lin YS, Zakusilo FT, Lu JY, Ablaeva J, Miller RA, Nevo E, Seluanov A, Gorbunova V. Evolution of High-Molecular-Mass Hyaluronic Acid is Associated with Subterranean Lifestyle. Biorxiv : the Preprint Server For Biology. PMID 37215017 DOI: 10.1101/2023.05.08.539764  0.336
2022 Zhao Y, Simon M, Seluanov A, Gorbunova V. DNA damage and repair in age-related inflammation. Nature Reviews. Immunology. PMID 35831609 DOI: 10.1038/s41577-022-00751-y  0.349
2022 Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, ... ... Gorbunova V, et al. Meeting Report: Aging Research and Drug Discovery. Aging. 14. PMID 35089871 DOI: 10.18632/aging.203859  0.37
2021 Horvath S, Haghani A, Macoretta N, Ablaeva J, Zoller JA, Li CZ, Zhang J, Takasugi M, Zhao Y, Rydkina E, Zhang Z, Emmrich S, Raj K, Seluanov A, Faulkes CG, ... Gorbunova V, et al. DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders. Nature Aging. 2: 46-59. PMID 35368774 DOI: 10.1038/s43587-021-00152-1  0.332
2021 Zhang Q, Tombline G, Ablaeva J, Zhang L, Zhou X, Smith Z, Zhao Y, Xiaoli AM, Wang Z, Lin JR, Jabalameli MR, Mitra J, Nguyen N, Vijg J, Seluanov A, ... ... Gorbunova V, et al. Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidation. Cell Reports. 37: 109965. PMID 34758328 DOI: 10.1016/j.celrep.2021.109965  0.317
2021 Zhang L, Dong X, Tian X, Lee M, Ablaeva J, Firsanov D, Lee SG, Maslov AY, Gladyshev VN, Seluanov A, Gorbunova V, Vijg J. Maintenance of genome sequence integrity in long- and short-lived rodent species. Science Advances. 7: eabj3284. PMID 34705500 DOI: 10.1126/sciadv.abj3284  0.616
2021 Zhao Y, Oreskovic E, Zhang Q, Lu Q, Gilman A, Lin YS, He J, Zheng Z, Lu JY, Lee J, Ke Z, Ablaeva J, Sweet MJ, Horvath S, Zhang Z, ... ... Gorbunova V, et al. Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Nature Immunology. PMID 34556881 DOI: 10.1038/s41590-021-01027-8  0.437
2021 Buffenstein R, Amoroso V, Andziak B, Avdieiev S, Azpurua J, Barker AJ, Bennett NC, Brieño-Enríquez MA, Bronner GN, Coen C, Delaney MA, Dengler-Crish CM, Edrey YH, Faulkes CG, Frankel D, ... ... Gorbunova V, et al. The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology. Biological Reviews of the Cambridge Philosophical Society. PMID 34476892 DOI: 10.1111/brv.12791  0.76
2021 Zhao Y, Seluanov A, Gorbunova V. Revelations About Aging and Disease from Unconventional Vertebrate Model Organisms. Annual Review of Genetics. PMID 34416119 DOI: 10.1146/annurev-genet-071719-021009  0.306
2020 Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, ... ... Gorbunova V, et al. ARDD 2020: from aging mechanisms to interventions. Aging. 12. PMID 33378272 DOI: 10.18632/aging.202454  0.373
2020 Simon M, Emmrich S, Seluanov A, Gorbunova V. A hairy tale: SIRT7 safeguards skin stem cells during aging. The Embo Journal. e106294. PMID 32803757 DOI: 10.15252/Embj.2020106294  0.305
2020 Zhou X, Dou Q, Fan G, Zhang Q, Sanderford M, Kaya A, Johnson J, Karlsson EK, Tian X, Mikhalchenko A, Kumar S, Seluanov A, Zhang ZD, Gorbunova V, Liu X, et al. Beaver and Naked Mole Rat Genomes Reveal Common Paths to Longevity. Cell Reports. 32: 107949. PMID 32726638 DOI: 10.1016/J.Celrep.2020.107949  0.68
2020 Zhao J, Tian X, Zhu Y, Zhang Z, Rydkina E, Yuan Y, Zhang H, Roy B, Cornwell A, Nevo E, Shang X, Huang R, Kristiansen K, Seluanov A, Fang X, ... Gorbunova V, et al. Reply to: Transformation of naked mole-rat cells. Nature. 583: E8-E13. PMID 32612220 DOI: 10.1038/S41586-020-2411-9  0.657
2020 Takasugi M, Firsanov D, Tombline G, Ning H, Ablaeva J, Seluanov A, Gorbunova V. Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties. Nature Communications. 11: 2376. PMID 32398747 DOI: 10.1038/S41467-020-16050-W  0.336
2020 Kumar V, Agrawal R, Pandey A, Kopf S, Hoeffgen M, Kaymak S, Bandapalli OR, Gorbunova V, Seluanov A, Mall MA, Herzig S, Nawroth PP. Compromised DNA repair is responsible for diabetes-associated fibrosis. The Embo Journal. e103477. PMID 32338774 DOI: 10.15252/Embj.2019103477  0.313
2020 Chesnokova VM, Zonis S, Apostolou N, Hannah EQ, Knott S, Wawrowsky K, Ben-Shlomo A, Barrett R, Gorbunova V, Karalis K, Melmed S. OR16-06 Age-Associated Local GH Promotes Colon Neoplasia Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1474  0.417
2019 Tombline G, Gigas J, Macoretta N, Zacher M, Emmrich S, Zhao Y, Seluanov A, Gorbunova V. Proteomics of Long-Lived Mammals. Proteomics. e1800416. PMID 31737995 DOI: 10.1002/Pmic.201800416  0.444
2019 Chen Y, Zhang H, Xu Z, Tang H, Geng A, Cai B, Su T, Shi J, Jiang C, Tian X, Seluanov A, Huang J, Wan X, Jiang Y, Gorbunova V, et al. A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites. Nucleic Acids Research. PMID 31291457 DOI: 10.1093/Nar/Gkz592  0.76
2019 Katagi H, Louis N, Unruh D, Sasaki T, He X, Zhang A, Ma Q, Piunti A, Shimazu Y, Lamano JB, Carcaboso AM, Tian X, Seluanov A, Gorbunova V, Laurie KL, et al. Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31227500 DOI: 10.1158/1078-0432.Ccr-18-3890  0.624
2019 Bozek K, Khrameeva EE, Reznick J, Omerbašić D, Bennett NC, Lewin GR, Azpurua J, Gorbunova V, Seluanov A, Regnard P, Wanert F, Marchal J, Pifferi F, Aujard F, Liu Z, et al. Publisher Correction: Lipidome determinants of maximal lifespan in mammals. Scientific Reports. 9: 6972. PMID 31043659 DOI: 10.1038/S41598-019-43122-9  0.704
2019 Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, ... ... Gorbunova V, et al. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 177: 622-638.e22. PMID 31002797 DOI: 10.1016/J.Cell.2019.03.043  0.774
2019 Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, ... ... Gorbunova V, et al. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Science Translational Medicine. 11. PMID 30760578 DOI: 10.1126/Scitranslmed.Aaq1427  0.323
2019 Chesnokova V, Zonis S, Barrett R, Kameda H, Wawrowsky K, Ben-Shlomo A, Yamamoto M, Gleeson J, Bresee C, Gorbunova V, Melmed S. Excess growth hormone suppresses DNA damage repair in epithelial cells. Jci Insight. 4. PMID 30728323 DOI: 10.1172/Jci.Insight.125762  0.398
2019 Chesnokova V, Zonis S, Barrett R, Gleeson J, Gorbunova V, Melmed S. MON-475 Growth Hormone Induces Colon Tissue DNA Damage Independently of IGF-1 Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-475  0.307
2019 Gorbunova V. MECHANISMS OF LONGEVITY: LESSONS FROM LONG-LIVED MAMMALS Innovation in Aging. 3: S8-S8. DOI: 10.1093/Geroni/Igz038.026  0.407
2018 Seluanov A, Gladyshev VN, Vijg J, Gorbunova V. Mechanisms of cancer resistance in long-lived mammals. Nature Reviews. Cancer. PMID 29622806 DOI: 10.1038/S41568-018-0004-9  0.361
2018 Ghosh S, Wong SK, Jiang Z, Liu B, Wang Y, Hao Q, Gorbunova V, Liu X, Zhou Z. Haploinsufficiency ofdramatically extends the lifespan of Sirt6-deficient mice. Elife. 7. PMID 29474172 DOI: 10.7554/Elife.32127  0.322
2018 Zhao Y, Tyshkovskiy A, Muñoz-Espín D, Tian X, Serrano M, de Magalhaes JP, Nevo E, Gladyshev VN, Seluanov A, Gorbunova V. Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. PMID 29432174 DOI: 10.1073/Pnas.1721160115  0.717
2018 Tian X, Doerig K, Park R, Can Ran Qin A, Hwang C, Neary A, Gilbert M, Seluanov A, Gorbunova V. Evolution of telomere maintenance and tumour suppressor mechanisms across mammals. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29335367 DOI: 10.1098/Rstb.2016.0443  0.673
2018 Swovick K, Welle KA, Hryhorenko J, Seluanov A, Gorbunova V, Ghaemmaghami S. Cross-species comparison of proteome turnover kinetics. Molecular & Cellular Proteomics : McP. PMID 29321186 DOI: 10.1074/Mcp.Ra117.000574  0.303
2017 Tan L, Ke Z, Tombline G, Macoretta N, Hayes K, Tian X, Lv R, Ablaeva J, Gilbert M, Bhanu NV, Yuan ZF, Garcia BA, Shi YG, Shi Y, Seluanov A, ... Gorbunova V, et al. Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. Stem Cell Reports. PMID 29107597 DOI: 10.1016/J.Stemcr.2017.10.001  0.678
2017 Piscitello D, Varshney D, Lilla S, Vizioli MG, Reid C, Gorbunova V, Seluanov A, Gillespie DA, Adams PD. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11. Oncogene. PMID 28967905 DOI: 10.1038/Onc.2017.340  0.398
2017 Tian X, Seluanov A, Gorbunova V. Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species. Trends in Endocrinology and Metabolism: Tem. PMID 28888702 DOI: 10.1016/J.Tem.2017.07.004  0.676
2017 Nieborowska-Skorska M, Sullivan K, Dasgupta Y, Podszywalow-Bartnicka P, Hoser G, Maifrede S, Martinez E, Di Marcantonio D, Bolton-Gillespie E, Cramer-Morales K, Lee J, Li M, Slupianek A, Gritsyuk D, Cerny-Reiterer S, ... ... Gorbunova V, et al. Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells. The Journal of Clinical Investigation. PMID 28481221 DOI: 10.1172/Jci90825  0.411
2017 Tian X, Seluanov A, Gorbunova V. Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging. Cell Metabolism. 25: 991-992. PMID 28467943 DOI: 10.1016/J.Cmet.2017.04.022  0.673
2017 Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJ, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA. A conserved NAD(+) binding pocket that regulates protein-protein interactions during aging. Science (New York, N.Y.). 355: 1312-1317. PMID 28336669 DOI: 10.1126/Science.Aad8242  0.508
2017 Bozek K, Khrameeva EE, Reznick J, Omerbašić D, Bennett NC, Lewin GR, Azpurua J, Gorbunova V, Seluanov A, Regnard P, Wanert F, Marchal J, Pifferi F, Aujard F, Liu Z, et al. Lipidome determinants of maximal lifespan in mammals. Scientific Reports. 7: 5. PMID 28127055 DOI: 10.1038/S41598-017-00037-7  0.732
2017 Barzilai N, Gorbunova V, Sinclair D. LONG-LIVED ANIMAL MODELS AND HEALTH-SPAN EXTENSION IN STUDIES OF AGING Innovation in Aging. 1: 10-10. DOI: 10.1093/Geroni/Igx004.033  0.446
2016 Ma S, Upneja A, Galecki A, Tsai YM, Burant CF, Raskind S, Zhang Q, Zhang ZD, Seluanov A, Gorbunova V, Clish CB, Miller RA, Gladyshev VN. Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. Elife. 5. PMID 27874830 DOI: 10.7554/Elife.19130  0.359
2016 Van Meter M, Simon M, Tombline G, May A, Morello TD, Hubbard BP, Bredbenner K, Park R, Sinclair DA, Bohr VA, Gorbunova V, Seluanov A. JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks. Cell Reports. PMID 27568560 DOI: 10.1016/J.Celrep.2016.08.006  0.515
2016 Hewitt G, Carroll B, Sarallah R, Correia-Melo C, Ogrodnik M, Nelson G, Otten EG, Manni D, Antrobus R, Morgan BA, von Zglinicki T, Jurk D, Seluanov A, Gorbunova V, Johansen T, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 0. PMID 27391408 DOI: 10.1080/15548627.2016.1210368  0.39
2016 Patrick A, Seluanov M, Hwang C, Tam J, Khan T, Morgenstern A, Wiener L, Vazquez JM, Zafar H, Wen R, Muratkalyeva M, Doerig K, Zagorulya M, Cole L, Catalano S, ... ... Gorbunova V, et al. Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan. Aging. PMID 27163160  0.742
2016 Koschmann C, Calinescu AA, Nunez FJ, Mackay A, Fazal-Salom J, Thomas D, Mendez F, Kamran N, Dzaman M, Mulpuri L, Krasinkiewicz J, Doherty R, Lemons R, Brosnan-Cashman JA, Li Y, ... ... Gorbunova V, et al. ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma. Science Translational Medicine. 8: 328ra28. PMID 26936505 DOI: 10.1126/Scitranslmed.Aac8228  0.366
2016 Gorbunova V, Seluanov A. DNA double strand break repair, aging and the chromatin connection. Mutation Research. 788: 2-6. PMID 26923716 DOI: 10.1016/J.Mrfmmm.2016.02.004  0.375
2016 Ma S, Upneja A, Galecki A, Tsai Y, Burant CF, Raskind S, Zhang Q, Zhang ZD, Seluanov A, Gorbunova V, Clish CB, Miller RA, Gladyshev VN. Author response: Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity Elife. DOI: 10.7554/Elife.19130.019  0.36
2015 MacRae SL, Croken MM, Calder RB, Aliper A, Milholland B, White RR, Zhavoronkov A, Gladyshev VN, Seluanov A, Gorbunova V, Zhang ZD, Vijg J. DNA repair in species with extreme lifespan differences. Aging. PMID 26729707  0.318
2015 Brohus M, Gorbunova V, Faulkes CG, Overgaard MT, Conover CA. The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat. Plos One. 10: e0145587. PMID 26694858 DOI: 10.1371/Journal.Pone.0145587  0.351
2015 Fang X, Nevo E, Han L, Levanon EY, Zhao J, Avivi A, Larkin D, Jiang X, Feranchuk S, Zhu Y, Fishman A, Feng Y, Sher N, Xiong Z, Hankeln T, ... ... Gorbunova V, et al. Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax. Nature Communications. 6: 8051. PMID 26264976 DOI: 10.1038/Ncomms9051  0.74
2015 MacRae SL, Zhang Q, Lemetre C, Seim I, Calder RB, Hoeijmakers J, Suh Y, Gladyshev VN, Seluanov A, Gorbunova V, Vijg J, Zhang ZD. Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human. Aging Cell. 14: 288-91. PMID 25645816 DOI: 10.1111/Acel.12314  0.375
2015 Xu Z, Zhang L, Zhang W, Meng D, Zhang H, Jiang Y, Xu X, Van Meter M, Seluanov A, Gorbunova V, Mao Z. SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. Cell Cycle (Georgetown, Tex.). 14: 269-76. PMID 25607651 DOI: 10.4161/15384101.2014.980641  0.653
2015 Tian X, Azpurua J, Ke Z, Augereau A, Zhang ZD, Vijg J, Gladyshev VN, Gorbunova V, Seluanov A. INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform. Proceedings of the National Academy of Sciences of the United States of America. 112: 1053-8. PMID 25550505 DOI: 10.1073/Pnas.1418203112  0.784
2015 Koschmann C, Calinescu A, Nunez F, Mckay A, Salom JF, Thomas D, Mulpuri L, Kamran N, Mendez F, Dzaman M, Krasinkiewicz J, Lemons R, Zhao L, Appelman H, Ferguson D, ... Gorbunova V, et al. PTPS-15ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS NON-HOMOLOGOUS END JOINING DNA REPAIR IN GLIOMA Neuro-Oncology. 17: v182.2-v182. DOI: 10.1093/Neuonc/Nov228.15  0.367
2015 Koschmann C, Calinescu A, Thomas D, Nunez FJ, Dzaman M, Krasinkiewicz J, Kamran N, Lemons R, Mendez F, Li Y, Ferguson D, Gorbunova V, Roh S, Zhao L, Meeker A, et al. HG-02 * ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS GENETIC STABILITY IN GLIOBLASTOMA Neuro-Oncology. 17: iii10-iii11. DOI: 10.1093/Neuonc/Nov061.39  0.337
2014 Van Meter M, Kashyap M, Rezazadeh S, Geneva AJ, Morello TD, Seluanov A, Gorbunova V. SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. Nature Communications. 5: 5011. PMID 25247314 DOI: 10.1038/Ncomms6011  0.317
2014 Keane M, Craig T, Alföldi J, Berlin AM, Johnson J, Seluanov A, Gorbunova V, Di Palma F, Lindblad-Toh K, Church GM, de Magalhães JP. The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations. Bioinformatics (Oxford, England). 30: 3558-60. PMID 25172923 DOI: 10.1093/Bioinformatics/Btu579  0.356
2014 Vaidya A, Mao Z, Tian X, Spencer B, Seluanov A, Gorbunova V. Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age. Plos Genetics. 10: e1004511. PMID 25033455 DOI: 10.1371/Journal.Pgen.1004511  0.77
2014 Van Meter M, Gorbunova V, Seluanov A. SIRT6: a promising target for cancer prevention and therapy. Advances in Experimental Medicine and Biology. 818: 181-96. PMID 25001537 DOI: 10.1007/978-1-4471-6458-6_9  0.315
2014 Gorbunova V, Seluanov A, Zhang Z, Gladyshev VN, Vijg J. Comparative genetics of longevity and cancer: insights from long-lived rodents. Nature Reviews. Genetics. 15: 531-40. PMID 24981598 DOI: 10.1038/Nrg3728  0.366
2014 Fang X, Nevo E, Han L, Levanon EY, Zhao J, Avivi A, Larkin D, Jiang X, Feranchuk S, Zhu Y, Fishman A, Feng Y, Sher N, Xiong Z, Hankeln T, ... ... Gorbunova V, et al. Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax. Nature Communications. 5: 3966. PMID 24892994 DOI: 10.1038/Ncomms4966  0.754
2014 Hine CM, Li H, Xie L, Mao Z, Seluanov A, Gorbunova V. Regulation of Rad51 promoter. Cell Cycle (Georgetown, Tex.). 13: 2038-45. PMID 24781030 DOI: 10.4161/Cc.29016  0.778
2014 Cao Y, Xu Y, Zhang L, Li Z, Jiang Y, Tian X, Seluanov A, Gorbunova V, Mao Z. Utilization of Rad51C promoter for transcriptional targeting of cancer cells. Oncotarget. 5: 1805-11. PMID 24742710 DOI: 10.18632/Oncotarget.1792  0.765
2013 Yao H, Sundar IK, Gorbunova V, Rahman I. P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence. Plos One. 8: e80007. PMID 24244594 DOI: 10.1371/Journal.Pone.0080007  0.336
2013 Azpurua J, Ke Z, Chen IX, Zhang Q, Ermolenko DN, Zhang ZD, Gorbunova V, Seluanov A. Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage. Proceedings of the National Academy of Sciences of the United States of America. 110: 17350-5. PMID 24082110 DOI: 10.1073/Pnas.1313473110  0.754
2013 Tilgner K, Neganova I, Singhapol C, Saretzki G, Al-Aama JY, Evans J, Gorbunova V, Gennery A, Przyborski S, Stojkovic M, Armstrong L, Jeggo P, Lako M. Brief report: A human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors Stem Cells. 31: 2015-2023. PMID 23818183 DOI: 10.1002/Stem.1456  0.371
2013 Tian X, Azpurua J, Hine C, Vaidya A, Myakishev-Rempel M, Ablaeva J, Mao Z, Nevo E, Gorbunova V, Seluanov A. High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature. 499: 346-9. PMID 23783513 DOI: 10.1038/Nature12234  0.772
2013 Tilgner K, Neganova I, Moreno-Gimeno I, Al-Aama JY, Burks D, Yung S, Singhapol C, Saretzki G, Evans J, Gorbunova V, Gennery A, Przyborski S, Stojkovic M, Armstrong L, Jeggo P, et al. A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors Cell Death and Differentiation. 20: 1089-1100. PMID 23722522 DOI: 10.1038/Cdd.2013.44  0.411
2013 Azpurua J, Yang JN, Van Meter M, Liu Z, Kim J, Lobo Ladd AA, Coppi AA, Gorbunova V, Seluanov A. IGF1R levels in the brain negatively correlate with longevity in 16 rodent species. Aging. 5: 304-14. PMID 23651613  0.721
2013 Leu JD, Chiu YW, Lo CC, Chiang PH, Chiu SJ, Tsai CH, Hwang JJ, Chen RC, Gorbunova V, Lee YJ. Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity. International Journal of Radiation Biology. 89: 433-44. PMID 23362981 DOI: 10.3109/09553002.2013.767992  0.349
2012 Van Meter M, Seluanov A, Gorbunova V.  Forever young?  Exploring the link between rapamycin, longevity and cancer. Cell Cycle (Georgetown, Tex.). 11: 4296-7. PMID 23152185 DOI: 10.4161/Cc.22868  0.34
2012 Gorbunova V, Hine C, Tian X, Ablaeva J, Gudkov AV, Nevo E, Seluanov A. Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: 19392-6. PMID 23129611 DOI: 10.1073/Pnas.1217211109  0.79
2012 Mao Z, Tian X, Van Meter M, Ke Z, Gorbunova V, Seluanov A. Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence. Proceedings of the National Academy of Sciences of the United States of America. 109: 11800-5. PMID 22753495 DOI: 10.1073/Pnas.1200583109  0.791
2012 Mao Z, Ke Z, Gorbunova V, Seluanov A. Replicatively senescent cells are arrested in G1 and G2 phases. Aging. 4: 431-5. PMID 22745179  0.597
2012 Rahman I, Kinnula VL, Gorbunova V, Yao H. SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Preventive Medicine. 54: S20-8. PMID 22178470 DOI: 10.1016/J.Ypmed.2011.11.014  0.309
2012 Hine CM, Seluanov A, Gorbunova V. Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 347-55. PMID 22008909 DOI: 10.1038/Mt.2011.215  0.666
2011 Fong V, Osterbur M, Capella C, Kim YE, Hine C, Gorbunova V, Seluanov A, Dewhurst S. Adenoviral vector driven by a minimal Rad51 promoter is selective for p53-deficient tumor cells. Plos One. 6: e28714. PMID 22174876 DOI: 10.1371/Journal.Pone.0028714  0.687
2011 Van Meter M, Mao Z, Gorbunova V, Seluanov A. Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair. Aging. 3: 829-35. PMID 21946623  0.637
2011 Van Meter M, Mao Z, Gorbunova V, Seluanov A. SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells. Cell Cycle (Georgetown, Tex.). 10: 3153-8. PMID 21900744 DOI: 10.4161/Cc.10.18.17435  0.659
2011 Mao Z, Hine C, Tian X, Van Meter M, Au M, Vaidya A, Seluanov A, Gorbunova V. SIRT6 promotes DNA repair under stress by activating PARP1. Science (New York, N.Y.). 332: 1443-6. PMID 21680843 DOI: 10.1126/Science.1202723  0.779
2010 Seluanov A, Vaidya A, Gorbunova V. Establishing primary adult fibroblast cultures from rodents. Journal of Visualized Experiments : Jove. PMID 20972406 DOI: 10.3791/2033  0.347
2010 Seluanov A, Mao Z, Gorbunova V. Analysis of DNA double-strand break (DSB) repair in mammalian cells. Journal of Visualized Experiments : Jove. PMID 20864925 DOI: 10.3791/2002  0.668
2009 Seluanov A, Hine C, Azpurua J, Feigenson M, Bozzella M, Mao Z, Catania KC, Gorbunova V. Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America. 106: 19352-7. PMID 19858485 DOI: 10.1073/Pnas.0905252106  0.776
2009 Mao Z, Jiang Y, Liu X, Seluanov A, Gorbunova V. DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells. Neoplasia (New York, N.Y.). 11: 683-91. PMID 19568413 DOI: 10.1593/Neo.09312  0.655
2009 Gorbunova V, Seluanov A. Coevolution of telomerase activity and body mass in mammals: from mice to beavers. Mechanisms of Ageing and Development. 130: 3-9. PMID 18387652 DOI: 10.1016/J.Mad.2008.02.008  0.378
2008 Gorbunova V, Bozzella MJ, Seluanov A. Rodents for comparative aging studies: from mice to beavers. Age (Dordrecht, Netherlands). 30: 111-9. PMID 19424861 DOI: 10.1007/S11357-008-9053-4  0.373
2008 Hine CM, Seluanov A, Gorbunova V. Use of the Rad51 promoter for targeted anti-cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. 105: 20810-5. PMID 19106292 DOI: 10.1073/Pnas.0807990106  0.685
2008 Seluanov A, Hine C, Bozzella M, Hall A, Sasahara TH, Ribeiro AA, Catania KC, Presgraves DC, Gorbunova V. Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan. Aging Cell. 7: 813-23. PMID 18778411 DOI: 10.1111/J.1474-9726.2008.00431.X  0.788
2008 Mao Z, Bozzella M, Seluanov A, Gorbunova V. DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells. Cell Cycle (Georgetown, Tex.). 7: 2902-6. PMID 18769152 DOI: 10.4161/Cc.7.18.6679  0.663
2008 Mao Z, Bozzella M, Seluanov A, Gorbunova V. Comparison of nonhomologous end joining and homologous recombination in human cells. Dna Repair. 7: 1765-71. PMID 18675941 DOI: 10.1016/J.Dnarep.2008.06.018  0.665
2008 Dion V, Lin Y, Price BA, Fyffe SL, Seluanov A, Gorbunova V, Wilson JH. Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination. Dna Repair. 7: 313-20. PMID 18083071 DOI: 10.1016/J.Dnarep.2007.11.002  0.349
2007 Gorbunova V, Seluanov A, Mao Z, Hine C. Changes in DNA repair during aging. Nucleic Acids Research. 35: 7466-74. PMID 17913742 DOI: 10.1093/Nar/Gkm756  0.663
2007 Seluanov A, Danek J, Hause N, Gorbunova V. Changes in the level and distribution of Ku proteins during cellular senescence. Dna Repair. 6: 1740-8. PMID 17686666 DOI: 10.1016/J.Dnarep.2007.06.010  0.393
2007 Mao Z, Seluanov A, Jiang Y, Gorbunova V. TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 104: 13068-73. PMID 17670947 DOI: 10.1073/Pnas.0702410104  0.649
2007 Seluanov A, Chen Z, Hine C, Sasahara TH, Ribeiro AA, Catania KC, Presgraves DC, Gorbunova V. Telomerase activity coevolves with body mass not lifespan. Aging Cell. 6: 45-52. PMID 17173545 DOI: 10.1111/J.1474-9726.2006.00262.X  0.687
2007 Shi X, Seluanov A, Gorbunova V. Cell divisions are required for L1 retrotransposition. Molecular and Cellular Biology. 27: 1264-70. PMID 17145770 DOI: 10.1128/Mcb.01888-06  0.346
2005 Gorbunova V, Seluanov A. Making ends meet in old age: DSB repair and aging. Mechanisms of Ageing and Development. 126: 621-8. PMID 15888314 DOI: 10.1016/J.Mad.2005.02.008  0.384
2004 Gorbunova V, Seluanov A, Mittelman D, Wilson JH. Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells. Human Molecular Genetics. 13: 2979-89. PMID 15459182 DOI: 10.1093/Hmg/Ddh317  0.361
2004 Seluanov A, Mittelman D, Pereira-Smith OM, Wilson JH, Gorbunova V. DNA end joining becomes less efficient and more error-prone during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 101: 7624-9. PMID 15123826 DOI: 10.1073/Pnas.0400726101  0.443
2003 Gorbunova V, Seluanov A. Telomerase as a growth-promoting factor. Cell Cycle (Georgetown, Tex.). 2: 534-7. PMID 14504469 DOI: 10.4161/Cc.2.6.515  0.351
2003 Gorbunova V, Seluanov A, Dion V, Sandor Z, Meservy JL, Wilson JH. Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells. Molecular and Cellular Biology. 23: 4485-93. PMID 12808091 DOI: 10.1128/Mcb.23.13.4485-4493.2003  0.321
2003 Gorbunova V, Seluanov A, Pereira-Smith OM. Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts. The Journal of Biological Chemistry. 278: 7692-8. PMID 12496279 DOI: 10.1074/Jbc.M212944200  0.366
2002 Gorbunova V, Seluanov A, Pereira-Smith OM. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis. The Journal of Biological Chemistry. 277: 38540-9. PMID 12140282 DOI: 10.1074/Jbc.M202671200  0.376
2002 Gorbunova V, Seluanov A. CLK-1 protein has DNA binding activity specific to O(L) region of mitochondrial DNA. Febs Letters. 516: 279-84. PMID 11959146 DOI: 10.1016/S0014-5793(02)02568-1  0.33
2001 Seluanov A, Gorbunova V, Falcovitz A, Sigal A, Milyavsky M, Zurer I, Shohat G, Goldfinger N, Rotter V. Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53. Molecular and Cellular Biology. 21: 1552-64. PMID 11238892 DOI: 10.1128/Mcb.21.5.1552-1564.2001  0.355
2000 Gorbunova V, Avivi-Ragolski N, Shalev G, Kovalchuk I, Abbo S, Hohn B, Levy AA. A new hyperrecombinogenic mutant of Nicotiana tabacum Plant Journal. 24: 601-611. PMID 11123799 DOI: 10.1046/J.1365-313X.2000.00905.X  0.578
2000 Gorbunova V, Ramos C, Hohn B, Levy AA. A nuclear protein that binds specifically to several maize transposons is not essential for Ds1 excision Molecular and General Genetics. 263: 492-497. PMID 10821183 DOI: 10.1007/S004380051193  0.556
1999 Gorbunova V, Levy AA. How plants make ends meet: DNA double-strand break repair Trends in Plant Science. 4: 263-269. DOI: 10.1016/S1360-1385(99)01430-2  0.614
1997 Gorbunova V, Levy AA. Non-homologous DNA end joining in plant cells is associated with deletions and filler DNA insertions Nucleic Acids Research. 25: 4650-4657. PMID 9358178 DOI: 10.1093/Nar/25.22.4650  0.615
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