Nelson Fausto - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Molecular Biology, Pathology, Oncology

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Irudayaswamy A, Muthiah M, Zhou L, Hung H, Jumat NHB, Haque J, Teoh N, Farrell G, Riehle KJ, Lin JS, Su LL, Chan JK, Choolani M, Wong PC, Wee A, ... ... Fausto N, et al. Long Term Fate of Human Fetal Liver Progenitor Cells Transplanted in Injured Mouse Livers. Stem Cells (Dayton, Ohio). PMID 28960647 DOI: 10.1002/Stem.2710  0.465
2014 Riehle KJ, Johnson MM, Johansson F, Bauer RL, Hayes BJ, Gilbertson DG, Haran AC, Fausto N, Campbell JS. Tissue-type plasminogen activator is not necessary for platelet-derived growth factor-c activation. Biochimica Et Biophysica Acta. 1842: 318-25. PMID 24269585 DOI: 10.1016/J.Bbadis.2013.11.013  0.447
2014 Wright JH, Johnson MM, Shimizu-Albergine M, Bauer RL, Hayes BJ, Surapisitchat J, Hudkins KL, Riehle KJ, Johnson SC, Yeh MM, Bammler TK, Beyer RP, Gilbertson DG, Alpers CE, Fausto N, et al. Paracrine activation of hepatic stellate cells in platelet-derived growth factor C transgenic mice: evidence for stromal induction of hepatocellular carcinoma. International Journal of Cancer. Journal International Du Cancer. 134: 778-88. PMID 23929039 DOI: 10.1002/Ijc.28421  0.504
2013 Riehle KJ, Haque J, McMahan RS, Kavanagh TJ, Fausto N, Campbell JS. Sustained Glutathione Deficiency Interferes with the Liver Response to TNF-α and Liver Regeneration after Partial Hepatectomy in Mice. Journal of Liver: Disease & Transplantation. 1. PMID 24611135  0.81
2013 Obayashi Y, Campbell JS, Fausto N, Yeung RS. Impaired lipid accumulation in the liver of Tsc2-heterozygous mice during liver regeneration. Biochemical and Biophysical Research Communications. 437: 146-50. PMID 23810393 DOI: 10.1016/J.Bbrc.2013.06.056  0.504
2013 McMahan RS, Riehle KJ, Fausto N, Campbell JS. A disintegrin and metalloproteinase 17 regulates TNF and TNFR1 levels in inflammation and liver regeneration in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G25-34. PMID 23639813 DOI: 10.1152/Ajpgi.00326.2012  0.819
2012 Okada H, Honda M, Campbell JS, Sakai Y, Yamashita T, Takebuchi Y, Hada K, Shirasaki T, Takabatake R, Nakamura M, Sunagozaka H, Tanaka T, Fausto N, Kaneko S. Acyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development. Cancer Research. 72: 4459-71. PMID 22651928 DOI: 10.1158/0008-5472.Can-12-0028  0.429
2012 Fausto N, Campbell JS, Riehle KJ. Liver regeneration. Journal of Hepatology. 57: 692-4. PMID 22613006 DOI: 10.1016/J.Jhep.2012.04.016  0.425
2012 Fernando J, Sancho P, Fernández-Rodriguez CM, Lledó JL, Caja L, Campbell JS, Fausto N, Fabregat I. Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli. Journal of Cellular Physiology. 227: 1319-25. PMID 21604268 DOI: 10.1002/Jcp.22843  0.408
2011 Vaquero J, Riehle KJ, Fausto N, Campbell JS. Liver Regeneration after Partial Hepatectomy Is Not Impaired in Mice with Double Deficiency of Myd88 and IFNAR Genes. Gastroenterology Research and Practice. 2011: 727403. PMID 22216024 DOI: 10.1155/2011/727403  0.488
2011 Caja L, Sancho P, Bertran E, Ortiz C, Campbell JS, Fausto N, Fabregat I. The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms. Biochemical Pharmacology. 82: 1583-92. PMID 21864510 DOI: 10.1016/J.Bcp.2011.08.011  0.426
2011 Lai KK, Shang S, Lohia N, Booth GC, Masse DJ, Fausto N, Campbell JS, Beretta L. Extracellular matrix dynamics in hepatocarcinogenesis: a comparative proteomics study of PDGFC transgenic and Pten null mouse models. Plos Genetics. 7: e1002147. PMID 21731504 DOI: 10.1371/Journal.Pgen.1002147  0.374
2011 Vaquero J, Campbell JS, Haque J, McMahan RS, Riehle KJ, Bauer RL, Fausto N. Toll-like receptor 4 and myeloid differentiation factor 88 provide mechanistic insights into the cause and effects of interleukin-6 activation in mouse liver regeneration. Hepatology (Baltimore, Md.). 54: 597-608. PMID 21574169 DOI: 10.1002/Hep.24420  0.776
2011 Riehle KJ, Dan YY, Campbell JS, Fausto N. New concepts in liver regeneration. Journal of Gastroenterology and Hepatology. 26: 203-12. PMID 21199532 DOI: 10.1111/J.1440-1746.2010.06539.X  0.389
2011 Caja L, Bertran E, Campbell J, Fausto N, Fabregat I. The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells. Journal of Cellular Physiology. 226: 1214-23. PMID 20945437 DOI: 10.1002/Jcp.22439  0.418
2011 Campbell JS, Argast GM, Yuen SY, Hayes B, Fausto N. Inactivation of p38 MAPK during liver regeneration. The International Journal of Biochemistry & Cell Biology. 43: 180-8. PMID 20708092 DOI: 10.1016/J.Biocel.2010.08.002  0.402
2011 Vaquero J, Campbell J, Haque J, McMahan R, Bauer R, Fausto N. 48 HEPATOCYTE PROLIFERATION AFTER PARTIAL HEPATECTOMY IS ACCELERATED IN MYD88 NULL MICE DESPITE THE ABROGATION OF EARLY CYTOKINE ACTIVATION Journal of Hepatology. 54: S21-S22. DOI: 10.1016/S0168-8278(11)60050-0  0.786
2010 Haque JA, McMahan RS, Campbell JS, Shimizu-Albergine M, Wilson AM, Botta D, Bammler TK, Beyer RP, Montine TJ, Yeh MM, Kavanagh TJ, Fausto N. Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1704-17. PMID 20548286 DOI: 10.1038/Labinvest.2010.112  0.792
2010 Baek JY, Morris SM, Campbell J, Fausto N, Yeh MM, Grady WM. TGF-β inactivation and TGF-α overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer International Journal of Cancer. 127: 1060-1071. PMID 20020490 DOI: 10.1002/Ijc.25127  0.428
2010 Teoh N, Pyakurel P, Dan YY, Swisshelm K, Hou J, Mitchell C, Fausto N, Gu Y, Farrell G. Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis. Gastroenterology. 138: 1155-65.e1-2. PMID 19919837 DOI: 10.1053/J.Gastro.2009.11.008  0.427
2010 Johansson F, Vaquero J, Bruix J, Fausto N, Campbell J. 340 Sorafenib Treatment Inhibits Non-Parenchymal Cells After 2/3 Partial Hepatectomy in Mice, but Does Not Impair Liver Regeneration Gastroenterology. 138: S-784. DOI: 10.1016/S0016-5085(10)63614-1  0.471
2009 Li J, Campbell JS, Mitchell C, McMahan RS, Yu X, Riehle KJ, Bumgarner RE, Fausto N. Relationships between deficits in tissue mass and transcriptional programs after partial hepatectomy in mice. The American Journal of Pathology. 175: 947-57. PMID 19700759 DOI: 10.2353/Ajpath.2009.090043  0.778
2009 Thompson JA, White CC, Cox DP, Chan JY, Kavanagh TJ, Fausto N, Franklin CC. Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes. Free Radical Biology & Medicine. 46: 1614-25. PMID 19328227 DOI: 10.1016/J.Freeradbiomed.2009.03.016  0.393
2009 Arias IM, Alter HJ, Boyer JL, Cohen DE, Fausto N, Shafritz DA, Wolkoff AW. The Liver: Biology and Pathobiology: Fifth Edition The Liver: Biology and Pathobiology: Fifth Edition. 1-1191. DOI: 10.1002/9780470747919  0.312
2008 Carmona-Cuenca I, Roncero C, Sancho P, Caja L, Fausto N, Fernández M, Fabregat I. Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity. Journal of Hepatology. 49: 965-76. PMID 18845355 DOI: 10.1016/J.Jhep.2008.07.021  0.347
2008 Lesnikov V, Gorden N, Fausto N, Spaulding E, Campbell J, Shulman H, Fleming RE, Deeg HJ. Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of functional transferrin-receptor type 2. Apoptosis : An International Journal On Programmed Cell Death. 13: 1005-12. PMID 18561026 DOI: 10.1007/S10495-008-0233-6  0.384
2008 Teoh NC, Dan YY, Swisshelm K, Lehman S, Wright JH, Haque J, Gu Y, Fausto N. Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. Hepatology (Baltimore, Md.). 47: 2078-88. PMID 18506893 DOI: 10.1002/Hep.22194  0.406
2008 Langdale LA, Hoagland V, Benz W, Riehle KJ, Campbell JS, Liggitt DH, Fausto N. Suppressor of cytokine signaling expression with increasing severity of murine hepatic ischemia-reperfusion injury. Journal of Hepatology. 49: 198-206. PMID 18471922 DOI: 10.1016/J.Jhep.2008.03.014  0.344
2008 Riehle KJ, Campbell JS, McMahan RS, Johnson MM, Beyer RP, Bammler TK, Fausto N. Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3. The Journal of Experimental Medicine. 205: 91-103. PMID 18158318 DOI: 10.1084/Jem.20070820  0.805
2007 Campbell JS, Johnson MM, Bauer RL, Hudkins KL, Gilbertson DG, Riehle KJ, Yeh MM, Alpers CE, Fausto N. Targeting stromal cells for the treatment of platelet-derived growth factor C-induced hepatocellular carcinogenesis. Differentiation; Research in Biological Diversity. 75: 843-52. PMID 17999742 DOI: 10.1111/J.1432-0436.2007.00235.X  0.425
2007 Tang W, Lázaro CA, Campbell JS, Parks WT, Katze MG, Fausto N. Responses of nontransformed human hepatocytes to conditional expression of full-length hepatitis C virus open reading frame. The American Journal of Pathology. 171: 1831-46. PMID 17991716 DOI: 10.2353/Ajpath.2007.070413  0.667
2007 Coe KJ, Jia Y, Ho HK, Rademacher P, Bammler TK, Beyer RP, Farin FM, Woodke L, Plymate SR, Fausto N, Nelson SD. Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening. Chemical Research in Toxicology. 20: 1277-90. PMID 17702527 DOI: 10.1021/Tx7001349  0.344
2007 Cheung RS, Brooling JT, Johnson MM, Riehle KJ, Campbell JS, Fausto N. Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells. Carcinogenesis. 28: 2624-31. PMID 17698969 DOI: 10.1093/Carcin/Bgm184  0.808
2007 Yeh MM, Larson AM, Campbell JS, Fausto N, Rulyak SJ, Swanson PE. The expression of transforming growth factor-alpha in cirrhosis, dysplastic nodules, and hepatocellular carcinoma: an immunohistochemical study of 70 cases. The American Journal of Surgical Pathology. 31: 681-9. PMID 17460450 DOI: 10.1097/Pas.0B013E31802Ff7Aa  0.367
2007 Lázaro CA, Chang M, Tang W, Campbell J, Sullivan DG, Gretch DR, Corey L, Coombs RW, Fausto N. Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes. The American Journal of Pathology. 170: 478-89. PMID 17255316 DOI: 10.2353/Ajpath.2007.060789  0.637
2007 Nguyen LN, Furuya MH, Wolfraim LA, Nguyen AP, Holdren MS, Campbell JS, Knight B, Yeoh GC, Fausto N, Parks WT. Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation. Hepatology (Baltimore, Md.). 45: 31-41. PMID 17187411 DOI: 10.1002/Hep.21466  0.387
2007 Stoick-Cooper CL, Weidinger G, Riehle KJ, Hubbert C, Major MB, Fausto N, Moon RT. Distinct Wnt signaling pathways have opposing roles in appendage regeneration. Development (Cambridge, England). 134: 479-89. PMID 17185322 DOI: 10.1242/Dev.001123  0.311
2007 Jablonski EM, Mattocks MA, Sokolov E, Koniaris LG, Hughes FM, Fausto N, Pierce RH, McKillop IH. Decreased aquaporin expression leads to increased resistance to apoptosis in hepatocellular carcinoma. Cancer Letters. 250: 36-46. PMID 17084522 DOI: 10.1016/J.Canlet.2006.09.013  0.382
2006 Lederer SL, Walters KA, Proll S, Paeper B, Robinzon S, Boix L, Fausto N, Bruix J, Katze MG. Distinct cellular responses differentiating alcohol- and hepatitis C virus-induced liver cirrhosis. Virology Journal. 3: 98. PMID 17121680 DOI: 10.1186/1743-422X-3-98  0.379
2006 Ueno S, Campbell J, Fausto N. Reactive oxygen species derived from NADPH oxidase system is not essential for liver regeneration after partial hepatectomy. The Journal of Surgical Research. 136: 260-5. PMID 17046793 DOI: 10.1016/J.Jss.2006.05.039  0.389
2006 Fausto N. Involvement of the innate immune system in liver regeneration and injury. Journal of Hepatology. 45: 347-9. PMID 16854494 DOI: 10.1016/J.Jhep.2006.06.009  0.329
2006 Botta D, Shi S, White CC, Dabrowski MJ, Keener CL, Srinouanprachanh SL, Farin FM, Ware CB, Ladiges WC, Pierce RH, Fausto N, Kavanagh TJ. Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice. The Journal of Biological Chemistry. 281: 28865-75. PMID 16840778 DOI: 10.1074/Jbc.M605143200  0.439
2006 Dan YY, Riehle KJ, Lazaro C, Teoh N, Haque J, Campbell JS, Fausto N. Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Proceedings of the National Academy of Sciences of the United States of America. 103: 9912-7. PMID 16782807 DOI: 10.1073/Pnas.0603824103  0.435
2006 Han CY, Chiba T, Campbell JS, Fausto N, Chaisson M, Orasanu G, Plutzky J, Chait A. Reciprocal and coordinate regulation of serum amyloid A versus apolipoprotein A-I and paraoxonase-1 by inflammation in murine hepatocytes. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 1806-13. PMID 16709944 DOI: 10.1161/01.Atv.0000227472.70734.Ad  0.766
2006 Walters KA, Smith MW, Pal S, Thompson JC, Thomas MJ, Yeh MM, Thomas DL, Fitzgibbon M, Proll S, Fausto N, Gretch DR, Carithers RL, Shuhart MC, Katze MG. Identification of a specific gene expression pattern associated with HCV-induced pathogenesis in HCV- and HCV/HIV-infected individuals. Virology. 350: 453-64. PMID 16574185 DOI: 10.1016/J.Virol.2006.02.030  0.306
2006 Campbell JS, Riehle KJ, Brooling JT, Bauer RL, Mitchell C, Fausto N. Proinflammatory cytokine production in liver regeneration is Myd88-dependent, but independent of Cd14, Tlr2, and Tlr4. Journal of Immunology (Baltimore, Md. : 1950). 176: 2522-8. PMID 16456013 DOI: 10.4049/Jimmunol.176.4.2522  0.398
2006 Fausto N, Campbell JS, Riehle KJ. Liver regeneration. Hepatology (Baltimore, Md.). 43: S45-53. PMID 16447274 DOI: 10.1002/hep.20969  0.36
2006 Smith MW, Walters KA, Korth MJ, Fitzgibbon M, Proll S, Thompson JC, Yeh MM, Shuhart MC, Furlong JC, Cox PP, Thomas DL, Phillips JD, Kushner JP, Fausto N, Carithers RL, et al. Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients. Gastroenterology. 130: 179-87. PMID 16401481 DOI: 10.1053/J.Gastro.2005.08.015  0.399
2006 Riehle KJ, Croker B, Campbell J, Fausto N. Regulation of liver regeneration by suppressors of cytokine signaling-3 Journal of the American College of Surgeons. 203: S12. DOI: 10.1016/J.Jamcollsurg.2006.05.027  0.309
2005 Plumlee CR, Lazaro CA, Fausto N, Polyak SJ. Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells. Virology Journal. 2: 89. PMID 16324217 DOI: 10.1186/1743-422X-2-89  0.369
2005 Fausto N. Tweaking liver progenitor cells. Nature Medicine. 11: 1053-4. PMID 16211039 DOI: 10.1038/Nm1005-1053  0.44
2005 Fausto N, Riehle KJ. Mechanisms of liver regeneration and their clinical implications. Journal of Hepato-Biliary-Pancreatic Surgery. 12: 181-9. PMID 15995805 DOI: 10.1007/S00534-005-0979-Y  0.398
2005 Ho HK, White CC, Fernandez C, Fausto N, Kavanagh TJ, Nelson SD, Bruschi SA. Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 86: 354-64. PMID 15901913 DOI: 10.1093/Toxsci/Kfi205  0.331
2005 Brooling JT, Campbell JS, Mitchell C, Yeoh GC, Fausto N. Differential regulation of rodent hepatocyte and oval cell proliferation by interferon gamma. Hepatology (Baltimore, Md.). 41: 906-15. PMID 15799032 DOI: 10.1002/Hep.20645  0.431
2005 Campbell JS, Hughes SD, Gilbertson DG, Palmer TE, Holdren MS, Haran AC, Odell MM, Bauer RL, Ren HP, Haugen HS, Yeh MM, Fausto N. Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 102: 3389-94. PMID 15728360 DOI: 10.1073/Pnas.0409722102  0.494
2005 Wang HC, Chang WT, Chang WW, Wu HC, Huang W, Lei HY, Lai MD, Fausto N, Su IJ. Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology (Baltimore, Md.). 41: 761-70. PMID 15726643 DOI: 10.1002/Hep.20615  0.436
2005 Ho HK, Hu ZH, Tzung SP, Hockenbery DM, Fausto N, Nelson SD, Bruschi SA. BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death. Biochemical Pharmacology. 69: 147-57. PMID 15588723 DOI: 10.1016/J.Bcp.2004.08.030  0.37
2005 Mitchell C, Nivison M, Jackson LF, Fox R, Lee DC, Campbell JS, Fausto N. Heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration. The Journal of Biological Chemistry. 280: 2562-8. PMID 15536070 DOI: 10.1074/Jbc.M412372200  0.447
2004 Botta D, Franklin CC, White CC, Krejsa CM, Dabrowski MJ, Pierce RH, Fausto N, Kavanagh TJ. Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis. Free Radical Biology & Medicine. 37: 632-42. PMID 15288121 DOI: 10.1016/J.Freeradbiomed.2004.05.027  0.414
2004 Yan W, Lee H, Deutsch EW, Lazaro CA, Tang W, Chen E, Fausto N, Katze MG, Aebersold R. A dataset of human liver proteins identified by protein profiling via isotope-coded affinity tag (ICAT) and tandem mass spectrometry. Molecular & Cellular Proteomics : McP. 3: 1039-41. PMID 15269248 DOI: 10.1074/Mcp.D400001-Mcp200  0.671
2004 Argast GM, Campbell JS, Brooling JT, Fausto N. Epidermal growth factor receptor transactivation mediates tumor necrosis factor-induced hepatocyte replication. The Journal of Biological Chemistry. 279: 34530-6. PMID 15199050 DOI: 10.1074/Jbc.M405703200  0.436
2004 Fausto N. Liver regeneration and repair: hepatocytes, progenitor cells, and stem cells. Hepatology (Baltimore, Md.). 39: 1477-87. PMID 15185286 DOI: 10.1002/Hep.20214  0.369
2003 Smith MW, Yue ZN, Korth MJ, Do HA, Boix L, Fausto N, Bruix J, Carithers RL, Katze MG. Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers. Hepatology (Baltimore, Md.). 38: 1458-67. PMID 14647057 DOI: 10.1016/J.Hep.2003.09.024  0.439
2003 Wang HC, Wu HC, Chen CF, Fausto N, Lei HY, Su IJ. Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress. The American Journal of Pathology. 163: 2441-9. PMID 14633616 DOI: 10.1016/S0002-9440(10)63599-7  0.325
2003 Franklin CC, Rosenfeld-Franklin ME, White C, Kavanagh TJ, Fausto N. TGFbeta1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1535-7. PMID 12824300 DOI: 10.1096/Fj.02-0867Fje  0.387
2003 Geiss GK, Carter VS, He Y, Kwieciszewski BK, Holzman T, Korth MJ, Lazaro CA, Fausto N, Bumgarner RE, Katze MG. Gene expression profiling of the cellular transcriptional network regulated by alpha/beta interferon and its partial attenuation by the hepatitis C virus nonstructural 5A protein Journal of Virology. 77: 6367-6375. PMID 12743294 DOI: 10.1128/Jvi.77.11.6367-6375.2003  0.35
2003 Fausto N, Campbell JS. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mechanisms of Development. 120: 117-30. PMID 12490302 DOI: 10.1016/S0925-4773(02)00338-6  0.458
2002 Mitchell C, Fausto N. Bone marrow-derived hepatocytes : rare but promising. The American Journal of Pathology. 161: 349-50. PMID 12163357 DOI: 10.1016/S0002-9440(10)64188-0  0.383
2002 Pierce RH, Franklin CC, Campbell JS, Tonge RP, Chen W, Fausto N, Nelson SD, Bruschi SA. Cell culture model for acetaminophen-induced hepatocyte death in vivo. Biochemical Pharmacology. 64: 413-24. PMID 12147292 DOI: 10.1016/S0006-2952(02)01180-2  0.416
2002 Chaisson ML, Brooling JT, Ladiges W, Tsai S, Fausto N. Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy. The Journal of Clinical Investigation. 110: 193-202. PMID 12122111 DOI: 10.1172/Jci15295  0.813
2002 Franklin CC, Krejsa CM, Pierce RH, White CC, Fausto N, Kavanagh TJ. Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death. The American Journal of Pathology. 160: 1887-94. PMID 12000740 DOI: 10.1016/S0002-9440(10)61135-2  0.319
2002 Pierce RH, Vail ME, Ralph L, Campbell JS, Fausto N. Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci. The American Journal of Pathology. 160: 1555-60. PMID 12000706 DOI: 10.1016/S0002-9440(10)61101-7  0.806
2002 Li ZY, Otto K, Richard RE, Ni S, Kirillova I, Fausto N, Blau CA, Lieber A. Dimerizer-induced proliferation of genetically modified hepatocytes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 420-6. PMID 11945069 DOI: 10.1006/Mthe.2002.0565  0.404
2002 Vail ME, Chaisson ML, Thompson J, Fausto N. Bcl-2 expression delays hepatocyte cell cycle progression during liver regeneration. Oncogene. 21: 1548-55. PMID 11896583 DOI: 10.1038/Sj.Onc.1205212  0.791
2002 Fausto N. Genetic engineering of liver cells for survival and proliferation Journal of Hepatology. 36: 858-859. DOI: 10.1016/S0168-8278(02)00130-7  0.361
2001 Adams ML, Pierce RH, Vail ME, White CC, Tonge RP, Kavanagh TJ, Fausto N, Nelson SD, Bruschi SA. Enhanced acetaminophen hepatotoxicity in transgenic mice overexpressing BCL-2. Molecular Pharmacology. 60: 907-15. PMID 11641418 DOI: 10.1124/Mol.60.5.907  0.766
2001 Fausto N. A mouse model for hepatitis C virus infection? Nature Medicine. 7: 890-1. PMID 11479615 DOI: 10.1038/90917  0.384
2001 Campbell JS, Prichard L, Schaper F, Schmitz J, Stephenson-Famy A, Rosenfeld ME, Argast GM, Heinrich PC, Fausto N. Expression of suppressors of cytokine signaling during liver regeneration. The Journal of Clinical Investigation. 107: 1285-92. PMID 11375418 DOI: 10.1172/Jci11867  0.389
2001 Vail ME, Pierce RH, Fausto N. Bcl-2 delays and alters hepatic carcinogenesis induced by transforming growth factor alpha. Cancer Research. 61: 594-601. PMID 11212255  0.769
2001 Knight B, Yeoh GC, Husk KL, Ly T, Abraham LJ, Yu C, Rhim JA, Fausto N. Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice. The Journal of Experimental Medicine. 192: 1809-18. PMID 11120777 DOI: 10.1084/Jem.192.12.1809  0.523
2000 Pierce RH, Campbell JS, Stephenson AB, Franklin CC, Chaisson M, Poot M, Kavanagh TJ, Rabinovitch PS, Fausto N. Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line. The American Journal of Pathology. 157: 221-36. PMID 10880392 DOI: 10.1016/S0002-9440(10)64533-6  0.782
2000 Rosenfeld ME, Prichard L, Shiojiri N, Fausto N. Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. The American Journal of Pathology. 156: 997-1007. PMID 10702415 DOI: 10.1016/S0002-9440(10)64967-X  0.545
1999 Fausto N. V. Knocking out genes to study liver regeneration: present and future. American Journal of Physiology. Gastrointestinal and Liver Physiology. 277: G917-G921. PMID 29591422 DOI: 10.1152/Ajpgi.1999.277.5.G917  0.464
1999 Fausto N. Mouse liver tumorigenesis: models, mechanisms, and relevance to human disease. Seminars in Liver Disease. 19: 243-52. PMID 10518304 DOI: 10.1055/S-2007-1007114  0.504
1999 Fausto N. Mechanisms of Liver Regeneration and Hepatocarcinogenesis Kanzo. 40: 66-66. DOI: 10.2957/Kanzo.40.Supl1_66  0.415
1999 Yamada Y, Webber EM, Kirillova I, Peschon JJ, Fausto N. Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor European Journal of Gastroenterology & Hepatology. 11: 51. DOI: 10.1097/00042737-199901000-00011  0.31
1998 Webber EM, Bruix J, Pierce RH, Fausto N. Tumor necrosis factor primes hepatocytes for DNA replication in the rat. Hepatology (Baltimore, Md.). 28: 1226-34. PMID 9794905 DOI: 10.1002/Hep.510280509  0.443
1998 Yamada Y, Webber EM, Kirillova I, Peschon JJ, Fausto N. Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: requirement for type 1 but not type 2 receptor. Hepatology (Baltimore, Md.). 28: 959-70. PMID 9755232 DOI: 10.1002/HEP.510280410  0.37
1998 Scatena M, Almeida M, Chaisson ML, Fausto N, Nicosia RF, Giachelli CM. NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival. The Journal of Cell Biology. 141: 1083-93. PMID 9585425 DOI: 10.1083/Jcb.141.4.1083  0.769
1997 Kay MA, Fausto N. Liver regeneration: prospects for therapy based on new technologies. Molecular Medicine Today. 3: 108-15. PMID 9095485 DOI: 10.1016/S1357-4310(96)10062-9  0.431
1997 Yamada Y, Kirillova I, Peschon JJ, Fausto N. Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proceedings of the National Academy of Sciences of the United States of America. 94: 1441-6. PMID 9037072 DOI: 10.1073/Pnas.94.4.1441  0.497
1996 Oguey D, Dumenco LL, Pierce RH, Fausto N. Analysis of the tumorigenicity of the X gene of hepatitis B virus in a nontransformed hepatocyte cell line and the effects of cotransfection with a murine p53 mutant equivalent to human codon 249. Hepatology (Baltimore, Md.). 24: 1024-33. PMID 8903370 DOI: 10.1002/Hep.510240508  0.372
1996 Fausto N, Laird AD, Webber EM. Liver regeneration. 2. Role of growth factors and cytokines in hepatic regeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1527-36. PMID 8529831 DOI: 10.1096/Fasebj.9.15.8529831  0.485
1995 Lieber A, Vrancken Peeters MJ, Meuse L, Fausto N, Perkins J, Kay MA. Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo. Proceedings of the National Academy of Sciences of the United States of America. 92: 6210-4. PMID 7597103 DOI: 10.1073/Pnas.92.13.6210  0.399
1995 Dumenco L, Oguey D, Wu J, Messier N, Fausto N. Introduction of a murine p53 mutation corresponding to human codon 249 into a murine hepatocyte cell line results in growth advantage, but not in transformation Hepatology. 22: 1279-1288. DOI: 10.1016/0270-9139(95)90640-1  0.348
1994 Wu JC, Merlino G, Fausto N. Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha. Proceedings of the National Academy of Sciences of the United States of America. 91: 674-8. PMID 7904757 DOI: 10.1073/Pnas.91.2.674  0.43
1993 Fausto N, Lemire JM, Shiojiri N. Cell lineages in hepatic development and the identification of progenitor cells in normal and injured liver. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 204: 237-41. PMID 7694302 DOI: 10.3181/00379727-204-43659  0.411
1993 Webber EM, Fitzgerald MJ, Brown PI, Bartlett MH, Fausto N. Transforming growth factor-α expression during liver regeneration after partial hepatectomy and toxic injury, and potential interactions between transforming growth factor-α and hepatocyte growth factor Hepatology. 18: 1422-1431. DOI: 10.1002/Hep.1840180622  0.344
1992 Fausto N. Growth factors in liver development, regeneration and carcinogenesis. Progress in Growth Factor Research. 3: 219-34. PMID 1667366 DOI: 10.1016/0955-2235(91)90008-R  0.502
1991 Fausto N. Protooncogenes and growth factors associated with normal and abnormal liver growth. Digestive Diseases and Sciences. 36: 653-8. PMID 2022167 DOI: 10.1007/Bf01297034  0.424
1991 Fausto N. Hepatocyte differentiation and liver progenitor cells. Current Opinion in Cell Biology. 2: 1036-42. PMID 1966006 DOI: 10.1016/0955-0674(90)90153-6  0.322
1991 Castilla A, Prieto J, Fausto N. Transforming growth factors beta 1 and alpha in chronic liver disease. Effects of interferon alfa therapy. The New England Journal of Medicine. 324: 933-40. PMID 1900574 DOI: 10.1056/Nejm199104043241401  0.435
1991 Jakowlew SB, Mead JE, Danielpour D, Wu J, Roberts AB, Fausto N. Transforming growth factor-beta (TGF-beta) isoforms in rat liver regeneration: messenger RNA expression and activation of latent TGF-beta Cell Regulation. 2: 535-548. PMID 1782214 DOI: 10.1091/Mbc.2.7.535  0.374
1991 Gruppuso PA, Curran TR, Mead JE, Fausto N, Oh W. Fetal growth factors as determinants of intrauterine hepatic growth Diabetes. 40: 51-55. PMID 1660827 DOI: 10.2337/Diab.40.2.S51  0.352
1991 Castilla A, Vázquez J, Simón M, Prieto J, Fausto N. Liver cell proliferation (LCP) in the natural history of chronic viral liver disease (CVLD) Journal of Hepatology. 13: S18. DOI: 10.1016/0168-8278(91)91062-L  0.428
1990 Jhappan C, Stahle C, Harkins RN, Fausto N, Smith GH, Merlino GT. TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell. 61: 1137-46. PMID 2350785 DOI: 10.1016/0092-8674(90)90076-Q  0.427
1990 Fausto N, Mead JE, Gruppuso PA, Braun L. TGF-β in liver development, regeneration, and carcinogenesis Annals of the New York Academy of Sciences. 593: 231-242. PMID 2165377 DOI: 10.1111/J.1749-6632.1990.Tb16115.X  0.368
1990 Fausto N, Mead JE. Regulation of liver growth: protooncogenes and transforming growth factors. Laboratory Investigation. 60: 4-13. DOI: 10.1007/978-1-4612-0485-5_1  0.479
1989 Mead JE, Fausto N. Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proceedings of the National Academy of Sciences of the United States of America. 86: 1558-62. PMID 2922399 DOI: 10.1073/Pnas.86.5.1558  0.38
1988 Braun L, Mead JE, Panzica M, Mikumo R, Bell GI, Fausto N. Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation. Proceedings of the National Academy of Sciences of the United States of America. 85: 1539-43. PMID 3422749 DOI: 10.1073/Pnas.85.5.1539  0.393
1988 Goyette M, Dolan M, Kaufmann W, Kaufman D, Shank PR, Fausto N. Transforming activity of DNA from rat liver tumors induced by the carcinogen methyl(acetoxymethyl)nitrosamine Molecular Carcinogenesis. 1: 26-32. PMID 2855600 DOI: 10.1002/Mc.2940010108  0.383
1986 Petropoulos CJ, Yaswen P, Panzica M, Fausto N. Methylation of the alphafetoprotein gene in cell populations isolated from rat livers during carcinogenesis. Nucleic Acids Research. 13: 8105-18. PMID 2415927 DOI: 10.1093/Nar/13.22.8105  0.345
1985 Yaswen P, Goyette M, Shank PR, Fausto N. Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis Molecular and Cellular Biology. 5: 780-786. PMID 2581126 DOI: 10.1128/Mcb.5.4.780  0.368
1984 Goyette M, Petropoulos CJ, Shank PR, Fausto N. Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver Molecular and Cellular Biology. 4: 1493-1498. PMID 6493228 DOI: 10.1128/Mcb.4.8.1493  0.354
1984 Fausto N. Messenger RNA in regenerating liver: implications for the understanding of regulated growth. Molecular and Cellular Biochemistry. 59: 131-47. PMID 6200760 DOI: 10.1007/Bf00231309  0.438
1983 Fausto N, Shank PR. Oncogene expression in liver regeneration and hepatocarcinogenesis Hepatology. 3: 1016-1023. PMID 6313506 DOI: 10.1002/Hep.1840030621  0.386
1983 Goyette M, Petropoulos CJ, Shank PR, Fausto N. Expression of a cellular oncogene during liver regeneration Science. 219: 510-512. PMID 6297003 DOI: 10.1126/Science.6297003  0.429
1981 Scholla CA, Petropoulos CJ, Becker FF, Fausto N. Alterations in polyadenylated messenger ribonucleic acid from free and total polysomes of a rat hepatoma. Biochemistry. 20: 3815-21. PMID 6115671 DOI: 10.1021/Bi00516A023  0.348
1979 Atryzek V, Fausto N. Accumulation of polyadenylated mRNA during liver regeneration. Biochemistry. 18: 1281-7. PMID 427113 DOI: 10.1021/Bi00574A025  0.362
1978 Tedeschi MV, Colbert DA, Fausto N. Transcription of the non-repetitive genome in liver hypertrophy and the homology between nuclear RNA of normal and 12 H-regenerating liver. Biochimica Et Biophysica Acta. 521: 641-9. PMID 737183 DOI: 10.1016/0005-2787(78)90305-2  0.364
1977 Colbert DA, Tedeschi MV, Atryzek V, Fausto N. Diversity of polyadenylated messenger RNA sequences in normal and 12-hr regenerating liver. Developmental Biology. 59: 111-23. PMID 892224 DOI: 10.1016/0012-1606(77)90246-9  0.392
1976 Fausto N, Butcher FR. Cyclic nucleotide levels in regenerating liver. Biochimica Et Biophysica Acta. 428: 702-6. PMID 179584 DOI: 10.1016/0304-4165(76)90200-2  0.356
1975 Greene RF, Fausto N. Studies on poly(A) sequences associated with regenerating liver RNA. Biochimica Et Biophysica Acta. 366: 23-34. PMID 4421170 DOI: 10.1016/0005-2787(74)90314-1  0.318
1974 Carlson GP, Fuller GC, Fausto N. Effects of spironolactone on carbon tetrachloride hepatotoxicity. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 145: 182-5. PMID 4149715 DOI: 10.3181/00379727-145-37773  0.371
1973 Levin S, Fausto N. Minor components of cytoplasmic ribonucleic acid from normal and regenerating rat livers. Biochemistry. 12: 1282-90. PMID 4696754 DOI: 10.1021/Bi00731A007  0.347
1973 Fausto N. The conversion of orotic acid into uridine 5'-monophosphate by isolated perfused normal and regenerating rat livers. The Biochemical Journal. 129: 811-20. PMID 4655818 DOI: 10.1042/Bj1290811  0.416
1973 Fausto N. RNA metabolism in isolated perfused normal and regenerating livers: polyamine effects. Biochimica Et Biophysica Acta. 281: 543-53. PMID 4653129 DOI: 10.1016/0005-2787(72)90155-4  0.339
1973 Brandt JT, Pierce DA, Fausto N. Ornithine decarboxylase activity and polyamine synthesis during kidney hypertrophy. Biochimica Et Biophysica Acta. 279: 184-93. PMID 4119904 DOI: 10.1016/0304-4165(72)90253-X  0.309
1972 Suarez KA, Carlson GP, Fuller GC, Fausto N. Differential acute effects of phenobarbital and 3-methylcholanthrene pretreatment on CCl4-induced hepatotoxicity in rats Toxicology and Applied Pharmacology. 23: 171-177. PMID 4403783 DOI: 10.1016/0041-008X(72)90180-9  0.311
1971 Fausto N. The control of ornithine decarboxylase activity during liver regeneration. Biochimica Et Biophysica Acta. 238: 116-28. PMID 5576616 DOI: 10.1016/0005-2787(71)90015-3  0.422
1970 Ariyama K, Fausto N, Tamvakopoulos E, van Lancker JL. Effects of X-Radiation on Amino Acid Incorporation into Regenerating Liver Proteins Radiation Research. 42: 528. DOI: 10.2307/3572968  0.36
1969 Fausto N. Studies on ornithine decarboxylase activity in normal and regenerating livers. Biochimica Et Biophysica Acta. 190: 193-201. PMID 5822849 DOI: 10.1016/0005-2787(69)90168-3  0.429
1969 Fausto N. The control of RNA synthesis during liver regeneration. OMP pyrophosphorylase and decarboxylase activities in normal and regenerating liver. Biochimica Et Biophysica Acta. 182: 66-75. PMID 5792859 DOI: 10.1016/0005-2787(69)90521-8  0.428
1964 Fausto N, Smoot AO, Lancker JLV. Early Effects of X-Irradiation on in Vitro DNA Synthesis in Mouse Spleen Radiation Research. 22: 288. DOI: 10.2307/3571660  0.332
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