| Year |
Citation |
Score |
| 2023 |
Wang S, Niroula S, Hoffman A, Khorrami M, Khorrami M, Yuan F, Gasser GN, Choi S, Liu B, Li J, Metersky ML, Vincent M, Crum CP, Boucher RC, Karmouty-Quintana H, et al. Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lung Is Not Resolved by CFTR Modulators. American Journal of Respiratory and Critical Care Medicine. PMID 37695863 DOI: 10.1164/rccm.202305-0818OC |
0.311 |
|
| 2023 |
Mikami Y, Grubb BR, Rogers TD, Dang H, Asakura T, Kota P, Gilmore RC, Okuda K, Morton LC, Sun L, Chen G, Wykoff JA, Ehre C, Vilar J, van Heusden C, ... ... Boucher RC, et al. Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration. Science Translational Medicine. 15: eabo7728. PMID 37285404 DOI: 10.1126/scitranslmed.abo7728 |
0.344 |
|
| 2022 |
Batson B, Zorn B, Radicioni G, Livengood S, Kumagai T, Dang H, Ceppe A, Clapp P, Tunney M, Elborn S, McElvaney G, Muhlebach M, Boucher RC, Tiemeyer M, Wolfgang M, et al. Cystic Fibrosis Airway Mucus Hyperconcentration Produces a Vicious Cycle of Mucin, Pathogen, and Inflammatory Interactions that Promote Disease Persistence. American Journal of Respiratory Cell and Molecular Biology. PMID 35486871 DOI: 10.1165/rcmb.2021-0359OC |
0.327 |
|
| 2022 |
Markovetz MR, Garbarine IC, Morrison CB, Kissner WJ, Seim I, Forest MG, Papanikolas MJ, Freeman R, Ceppe A, Ghio A, Alexis NE, Stick SM, Ehre C, Boucher RC, Esther CR, et al. Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 35437233 DOI: 10.1016/j.jcf.2022.04.008 |
0.31 |
|
| 2022 |
Kato T, Radicioni G, Papanikolas MJ, Stoychev GV, Markovetz MR, Aoki K, Porterfield M, Okuda K, Barbosa Cardenas SM, Gilmore RC, Morrison CB, Ehre C, Burns KA, White KK, Brennan TA, ... ... Boucher RC, et al. Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis. Science Advances. 8: eabm9718. PMID 35363522 DOI: 10.1126/sciadv.abm9718 |
0.585 |
|
| 2022 |
Singanayagam A, Footitt J, Marczynski M, Radicioni G, Cross MT, Finney LJ, Trujillo-Torralbo MB, Calderazzo MA, Zhu J, Aniscenko J, Clarke TB, Molyneaux PL, Bartlett NW, Moffatt MF, Cookson WO, ... ... Boucher RC, et al. Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease. The Journal of Clinical Investigation. PMID 35239513 DOI: 10.1172/JCI120901 |
0.318 |
|
| 2022 |
Hill DB, Button B, Rubinstein M, Boucher RC. Physiology and Pathophysiology of Human Airway Mucus. Physiological Reviews. PMID 35001665 DOI: 10.1152/physrev.00004.2021 |
0.561 |
|
| 2020 |
Lazarowski ER, Boucher RC. Purinergic receptors in airway hydration. Biochemical Pharmacology. 114387. PMID 33358825 DOI: 10.1016/j.bcp.2020.114387 |
0.353 |
|
| 2020 |
Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, Kato T, Asakura T, Gilmore RC, Morton LC, Lee RE, Mascenik T, Yin WN, Barbosa Cardenas SM, O'Neal YK, ... ... Boucher RC, et al. Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia. American Journal of Respiratory and Critical Care Medicine. PMID 33321047 DOI: 10.1164/rccm.202008-3198OC |
0.344 |
|
| 2020 |
Xu J, Livraghi-Butrico A, Hou X, Rajagopalan C, Zhang J, Song J, Jiang H, Wei HG, Wang H, Bouhamdan M, Ruan J, Yang D, Qiu Y, Youming X, Barrett RP, ... ... Boucher RC, et al. Phenotypes of CF rabbits generated by CRISPR/Cas9-mediated disruption of the CFTR gene. Jci Insight. PMID 33232302 DOI: 10.1172/jci.insight.139813 |
0.323 |
|
| 2020 |
Miyashita N, Horie M, Suzuki HI, Saito M, Mikami Y, Okuda K, Boucher RC, Suzukawa M, Hebisawa A, Saito A, Nagase T. FOXL1 Regulates Lung Fibroblast Function via Multiple Mechanisms. American Journal of Respiratory Cell and Molecular Biology. PMID 32946266 DOI: 10.1165/Rcmb.2019-0396Oc |
0.399 |
|
| 2020 |
Lewis BW, Choudhary I, Paudel K, Mao Y, Sharma R, Wang Y, Deshane JS, Boucher RC, Patial S, Saini Y. The Innate Lymphoid System Is a Critical Player in the Manifestation of Mucoinflammatory Airway Disease in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32817334 DOI: 10.4049/Jimmunol.2000530 |
0.38 |
|
| 2020 |
Bennett WD, Henderson AG, Ceppe A, Zeman KL, Wu J, Gladman C, Fuller F, Gazda S, Button B, Boucher RC, Donaldson SH. Effect of hypertonic saline on mucociliary clearance and clinical outcomes in chronic bronchitis. Erj Open Research. 6. PMID 32802823 DOI: 10.1183/23120541.00269-2020 |
0.383 |
|
| 2020 |
Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon KH, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, ... ... Boucher RC, et al. SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract. Cell. PMID 32526206 DOI: 10.1016/J.Cell.2020.05.042 |
0.355 |
|
| 2020 |
Rao W, Wang S, Duleba M, Niroula S, Goller K, Xie J, Mahalingam R, Neupane R, Liew AA, Vincent M, Okuda K, O'Neal WK, Boucher RC, Dickey BF, Wechsler ME, et al. Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis. Cell. PMID 32298651 DOI: 10.1016/J.Cell.2020.03.047 |
0.422 |
|
| 2020 |
McCarron A, Cmielewski P, Reyne N, McIntyre C, Finnie J, Craig F, Rout-Pitt N, Delhove J, Schjenken JE, Chan HY, Boog B, Knight E, Gilmore RC, O'Neal WK, Boucher RC, et al. Phenotypic characterization and comparison of Phe508del and cystic fibrosis transmembrane conductance regulator (CFTR) knockout rat models of cystic fibrosis generated by CRISPR/Cas9 gene editing. The American Journal of Pathology. PMID 32084371 DOI: 10.1016/J.Ajpath.2020.01.009 |
0.418 |
|
| 2019 |
Goralski JL, Chung SH, Glass TM, Ceppe AS, Akinnagbe-Zusterzeel EO, Trimble AT, Boucher RC, Soher BJ, Charles HC, Donaldson SH, Lee YZ. Dynamic perfluorinated gas MRI reveals abnormal ventilation despite normal FEV1 in cystic fibrosis. Jci Insight. PMID 31855577 DOI: 10.1172/Jci.Insight.133400 |
0.321 |
|
| 2019 |
van Heusden C, Button B, Anderson WH, Ceppe A, Morton LC, O'Neal WK, Dang H, Alexis NE, Donaldson SH, Stephan H, Boucher RC, Lazarowski ER. Inhibition of ATP hydrolysis restores airway surface liquid production in cystic fibrosis airway epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31800264 DOI: 10.1152/Ajplung.00449.2019 |
0.471 |
|
| 2019 |
Ramsey KA, Chen ACH, Radicioni G, Lourie R, Martin M, Broomfield A, Sheng YH, Hasnain SZ, Radford-Smith G, Simms LA, Burr L, Thornton DJ, Bowler SD, Livengood S, Ceppe A, ... ... Boucher RC, et al. Airway Mucus Hyperconcentration in Non-Cystic Fibrosis Bronchiectasis. American Journal of Respiratory and Critical Care Medicine. PMID 31765597 DOI: 10.1164/Rccm.201906-1219Oc |
0.428 |
|
| 2019 |
Chen G, Sun L, Kato T, Okuda K, Martino MB, Abzhanova A, Lin JM, Gilmore RC, Batson BD, O'Neal YK, Volmer AS, Dang H, Deng Y, Randell SH, Button B, ... ... Boucher RC, et al. IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis. The Journal of Clinical Investigation. PMID 31524632 DOI: 10.1172/Jci125669 |
0.341 |
|
| 2019 |
Boucher RC. Muco-Obstructive Lung Diseases. Reply. The New England Journal of Medicine. 381: e20. PMID 31483986 DOI: 10.1056/Nejmc1907962 |
0.359 |
|
| 2019 |
Markovetz MR, Subramani DB, Kissner WJ, Morrison CB, Garbarine IC, Ghio AL, Ramsey KA, Arora H, Kumar PA, Nix DB, Kumagai T, Krunkosky TM, Krause DC, Radicioni G, Alexis NE, ... ... Boucher RC, et al. Endotracheal Tube Mucus as a Source of Airway Mucus for Rheological Study. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 31389736 DOI: 10.1152/Ajplung.00238.2019 |
0.387 |
|
| 2019 |
Boucher RC. Muco-Obstructive Lung Diseases. The New England Journal of Medicine. 380: 1941-1953. PMID 31091375 DOI: 10.1056/Nejmra1813799 |
0.408 |
|
| 2019 |
Chen G, Ribeiro CMP, Sun L, Okuda K, Kato T, Gilmore RC, Martino MB, Dang H, Abzhanova A, Lin JM, Hull-Ryde EA, Volmer AS, Randell SH, Livraghi-Butrico A, Deng Y, ... ... Boucher RC, et al. XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in IPF Airway Epithelia. American Journal of Respiratory and Critical Care Medicine. PMID 30973754 DOI: 10.1164/Rccm.201810-1972Oc |
0.329 |
|
| 2019 |
Esther CR, Muhlebach MS, Ehre C, Hill DB, Wolfgang MC, Kesimer M, Ramsey KA, Markovetz MR, Garbarine IC, Forest MG, Seim I, Zorn B, Morrison CB, Delion MF, Thelin WR, ... ... Boucher RC, et al. Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis. Science Translational Medicine. 11. PMID 30944166 DOI: 10.1126/Scitranslmed.Aav3488 |
0.439 |
|
| 2019 |
Sherrard LJ, Einarsson GG, Johnston E, O'Neill K, McIlreavey L, McGrath SJ, Gilpin DF, Downey DG, Reid A, McElvaney NG, Boucher RC, Muhlebach MS, Elborn JS, Tunney MM. Assessment of stability and fluctuations of cultured lower airway bacterial communities in people with cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 30905581 DOI: 10.1016/J.Jcf.2019.02.012 |
0.353 |
|
| 2019 |
Ramsey KA, Radicioni G, Livengood S, Hill D, Ehre C, Alexis NE, Knowles MR, Noone PG, Daniels LA, Donaldson SH, McGuckin M, Kesimer M, Boucher RC. Airways Mucus Pathogenesis in Patients with Non-Cystic Fibrosis Bronchiectasis and Primary Ciliary Dyskinesia American Journal of Respiratory and Critical Care Medicine. 199. DOI: 10.1164/Ajrccm-Conference.2019.199.1_Meetingabstracts.A5708 |
0.408 |
|
| 2019 |
Einarsson G, Sherrard L, Zorn B, Hatch J, McGettigan C, Bradbury I, Campbell C, Johnston E, O'Neill K, McIlreavey L, McGrath S, Gilpin D, Murray M, Lavelle G, McElvaney G, ... ... Boucher R, et al. P140 Microbial community composition in cystic fibrosis patients during treatment for pulmonary exacerbation Journal of Cystic Fibrosis. 18: S97. DOI: 10.1016/S1569-1993(19)30434-5 |
0.318 |
|
| 2018 |
Mall MA, Danahay H, Boucher RC. Emerging Concepts and Therapies for Mucoobstructive Lung Disease. Annals of the American Thoracic Society. 15: S216-S226. PMID 30431343 DOI: 10.1513/Annalsats.201806-368Aw |
0.396 |
|
| 2018 |
Button B, Goodell HP, Atieh E, Chen YC, Williams R, Shenoy S, Lackey E, Shenkute NT, Cai LH, Dennis RG, Boucher RC, Rubinstein M. Roles of mucus adhesion and cohesion in cough clearance. Proceedings of the National Academy of Sciences of the United States of America. PMID 30420506 DOI: 10.1073/Pnas.1811787115 |
0.686 |
|
| 2018 |
Christenson SA, van den Berge M, Faiz A, Imkamp K, Bhakta N, Bonser LR, Zlock LT, Barjaktarevic IZ, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Comellas AP, Curtis JL, Han MK, et al. An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup. The Journal of Clinical Investigation. PMID 30383540 DOI: 10.1172/Jci121087 |
0.329 |
|
| 2018 |
Hill DB, Long RF, Kissner WJ, Atieh E, Garbarine IC, Markovetz MR, Fontana NC, Christy M, Habibpour M, Tarran R, Gregory Forest M, Boucher RC, Button B. Pathological Mucus and Impaired Mucus Clearance in Cystic Fibrosis Patients Results from Increased Concentration, not altered pH. The European Respiratory Journal. PMID 30361244 DOI: 10.1183/13993003.01297-2018 |
0.448 |
|
| 2018 |
Okuda K, Chen G, Subramani DB, Wolf M, Gilmore RC, Kato T, Radicioni G, Kesimer M, Chua M, Dang H, Livraghi-Butrico A, Ehre C, Doerschuk CM, Randell SH, Matsui H, ... ... Boucher RC, et al. Localization of Secretory Mucins MUC5AC and MUC5B in Normal/Healthy Human Airways. American Journal of Respiratory and Critical Care Medicine. PMID 30352166 DOI: 10.1164/Rccm.201804-0734Oc |
0.366 |
|
| 2018 |
Ehre C, Rushton ZL, Wang B, Hothem LN, Morrison CB, Fontana NC, Markovetz MR, Delion MF, Kato T, Villalon D, Thelin WR, Esther CR, Hill DB, Grubb BR, Livraghi-Butrico A, ... ... Boucher RC, et al. An Improved Inhaled Mucolytic to Treat Airway Muco-Obstructive Diseases. American Journal of Respiratory and Critical Care Medicine. PMID 30212240 DOI: 10.1164/Rccm.201802-0245Oc |
0.392 |
|
| 2018 |
Duncan GA, Kim N, Colon-Cortes Y, Rodriguez J, Mazur M, Birket SE, Rowe SM, West NE, Livraghi-Butrico A, Boucher RC, Hanes J, Aslanidi G, Suk JS. An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy. Molecular Therapy. Methods & Clinical Development. 9: 296-304. PMID 30038933 DOI: 10.1016/J.Omtm.2018.03.006 |
0.433 |
|
| 2018 |
Muhlebach MS, Hatch JE, Einarsson GG, McGrath SJ, Gilipin DF, Lavelle G, Mirkovic B, Murray MA, McNally P, Gotman N, Davis Thomas S, Wolfgang MC, Gilligan PH, McElvaney NG, Elborn JS, ... Boucher RC, et al. Anaerobic bacteria cultured from CF airways correlate to milder disease-a multisite study. The European Respiratory Journal. PMID 29946004 DOI: 10.1183/13993003.00242-2018 |
0.369 |
|
| 2018 |
Saini Y, Lewis BW, Yu D, Dang H, Livraghi-Butrico A, Del Piero F, O'Neal WK, Boucher RC. Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis. Physiological Reports. 6: e13677. PMID 29667749 DOI: 10.14814/Phy2.13677 |
0.37 |
|
| 2018 |
Goralski JL, Wu D, Thelin WR, Boucher RC, Button B. TheEffect of Nebulised Hypertonic Saline on Human Bronchial Epithelium. The European Respiratory Journal. PMID 29599187 DOI: 10.1183/13993003.02652-2017 |
0.379 |
|
| 2018 |
Chen G, Volmer AS, Wilkinson KJ, Deng Y, Jones LC, Yu D, Bustamante-Marin XM, Burns KA, Grubb BR, O'Neal WK, Livraghi-Butrico A, Boucher RC. Role of Spdef in the Regulation of Muc5b Expression in the Airways of Naïve and Muco-obstructed Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 29579396 DOI: 10.1165/Rcmb.2017-0127Oc |
0.374 |
|
| 2018 |
Martinez FJ, Han MK, Allinson JP, Barr RG, Boucher RC, Calverley P, Celli BR, Christenson SA, Crystal RG, Fagerås M, Freeman CM, Groenke L, Hoffman EA, Kesimer M, Kostikas K, et al. At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 29406779 DOI: 10.1164/Rccm.201710-2028Pp |
0.381 |
|
| 2018 |
Muhlebach MS, Zorn BT, Esther CR, Hatch JE, Murray CP, Turkovic L, Ranganathan SC, Boucher RC, Stick SM, Wolfgang MC. Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children. Plos Pathogens. 14: e1006798. PMID 29346420 DOI: 10.1371/Journal.Ppat.1006798 |
0.433 |
|
| 2018 |
Ramsey K, Radicioni G, Hill D, Ehre C, Button B, Alexis NE, Knowles M, Donaldson S, Kesimer M, Mcguckin M, Boucher R. Airways mucus pathogenesis in patients with non-cystic fibrosis bronchiectasis European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa5049 |
0.388 |
|
| 2018 |
Kady M, Christenson S, Stolberg V, Bates M, Labaki W, Alexis N, Barjaktarevic I, Barr G, Bleecker E, Boucher R, Bowler R, Cooper C, Couper D, Doerschuk C, Han M, et al. Lung dendritic cells correlate to small airway abnormality & lung CD4+ T cells: SPIROMICS bronchoscopy study European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Oa4925 |
0.325 |
|
| 2018 |
MCGettigan C, Spence C, Lee A, Sherrard L, Johnston E, Einarsson G, Elborn J, Downey D, Muhlebach M, Boucher R, MCElvaney G, Michelle M, Lavelle G, Tunney M, Gilpin D. P073 Use of qPCR to analyse changes in total bacterial and Pseudomonas aeruginosa load in cystic fibrosis patients when clinically stable and during exacerbations Journal of Cystic Fibrosis. 17: S80. DOI: 10.1016/S1569-1993(18)30370-9 |
0.303 |
|
| 2018 |
Einarsson G, Sherrard L, Johnston E, O'Neill K, McIlreavey L, MCGrath S, Gilpin D, Murray M, Lavelle G, MCElvaney G, Boucher R, Muhlebach M, Elborn J, Tunney M. P070 Longitudinal analysis of the lower airway microbiota in cystic fibrosis patients during clinical stability compared to those experiencing episodes of pulmonary exacerbation Journal of Cystic Fibrosis. 17: S79. DOI: 10.1016/S1569-1993(18)30367-9 |
0.372 |
|
| 2017 |
Kamei S, Fujikawa H, Nohara H, Ueno-Shuto K, Maruta K, Nakashima R, Kawakami T, Matsumoto C, Sakaguchi Y, Ono T, Suico MA, Boucher RC, Gruenert DC, Takeo T, Nakagata N, et al. Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells. Ebiomedicine. PMID 29289532 DOI: 10.1016/J.Ebiom.2017.12.025 |
0.474 |
|
| 2017 |
Wu D, Boucher RC, Button B, Elston T, Lin CL. An Integrated Mathematical Epithelial Cell Model for Airway Surface Liquid Regulation by Mechanical Forces. Journal of Theoretical Biology. PMID 29154907 DOI: 10.1016/J.Jtbi.2017.11.010 |
0.452 |
|
| 2017 |
Abdullah LH, Coakley R, Webster MJ, Zhu Y, Tarran R, Radicioni G, Kesimer M, Boucher RC, Davis CW, Ribeiro CMP. Mucin Production and Hydration Responses to Mucopurulent Materials in Normal vs. CF Airway Epithelia. American Journal of Respiratory and Critical Care Medicine. PMID 29099608 DOI: 10.1164/Rccm.201706-1139Oc |
0.474 |
|
| 2017 |
Livraghi-Butrico A, Wilkinson KJ, Volmer AS, Gilmore RC, Rogers TD, Caldwell RA, Burns KA, Esther CR, Mall MA, Boucher RC, O'Neal WK, Grubb BR. Lung disease phenotypes caused by over-expression of combinations of alpha, beta, and gamma subunits of the epithelial sodium channel in mouse airways. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00382.2017. PMID 29074490 DOI: 10.1152/Ajplung.00382.2017 |
0.388 |
|
| 2017 |
Kesimer M, Ford AA, Ceppe A, Radicioni G, Cao R, Davis CW, Doerschuk CM, Alexis NE, Anderson WH, Henderson AG, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, ... ... Boucher RC, et al. Airway Mucin Concentration as a Marker of Chronic Bronchitis. The New England Journal of Medicine. 377: 911-922. PMID 28877023 DOI: 10.1056/Nejmoa1701632 |
0.338 |
|
| 2017 |
Donoghue LJ, Livraghi-Butrico A, McFadden KM, Thomas JM, Chen G, Grubb BR, O'Neal WK, Boucher RC, Kelada SNP. Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1. Genetics. PMID 28851744 DOI: 10.1534/Genetics.117.300211 |
0.324 |
|
| 2017 |
Sandefur CI, Boucher RC, Elston TC. Mathematical model reveals role of nucleotide signaling in airway surface liquid homeostasis and its dysregulation in cystic fibrosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808008 DOI: 10.1073/Pnas.1617383114 |
0.447 |
|
| 2017 |
Woodruff PG, van den Berge M, Boucher RC, Brightling C, Burchard EG, Christenson SA, Han MK, Holtzman MJ, Kraft M, Lynch DA, Martinez FD, Reddel HK, Sin DD, Washko GR, Wenzel SE, et al. ATS-NHLBI Asthma COPD Overlap (ACO) Workshop Report. American Journal of Respiratory and Critical Care Medicine. PMID 28636425 DOI: 10.1164/Rccm.201705-0973Ws |
0.338 |
|
| 2017 |
Zeman KL, Rojas Balcazar J, Fuller F, Donn KH, Boucher RC, Bennett WD, Donaldson SH. A Trans-Nasal Aerosol Delivery Device for Efficient Pulmonary Deposition. Journal of Aerosol Medicine and Pulmonary Drug Delivery. PMID 28157412 DOI: 10.1089/Jamp.2016.1333 |
0.319 |
|
| 2017 |
Esther CR, Hill DB, Button B, Shi S, Jania CM, Duncan EA, Doerschuk CM, Chen G, Ranganathan S, Stick SM, Boucher RC. The sialic acid to urea ratio as a measure of airway surface hydration. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00398.2016. PMID 28062483 DOI: 10.1152/Ajplung.00398.2016 |
0.385 |
|
| 2016 |
Esther CR, Turkovic L, Rosenow T, Muhlebach MS, Boucher RC, Ranganathan S, Stick SM. Metabolomic biomarkers predictive of early structural lung disease in cystic fibrosis. The European Respiratory Journal. PMID 27836957 DOI: 10.1183/13993003.00524-2016 |
0.386 |
|
| 2016 |
Dickey BF, Fahy JV, Kesimer M, Boucher RC, Evans CM, Thornton D. Measuring Airway Mucin 2 in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization. Annals of the American Thoracic Society. 13: 2103-2104. PMID 27831803 DOI: 10.1513/Annalsats.201607-532Le |
0.363 |
|
| 2016 |
Cho JL, Ling MF, Adams DC, Faustino L, Islam SA, Afshar R, Griffith JW, Harris RS, Ng A, Radicioni G, Ford AA, Han AK, Xavier R, Kwok WW, Boucher R, et al. Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation. Science Translational Medicine. 8: 359ra132. PMID 27708065 DOI: 10.1126/Scitranslmed.Aag1370 |
0.34 |
|
| 2016 |
Stahr CS, Samarage CR, Donnelley M, Farrow N, Morgan KS, Zosky G, Boucher RC, Siu KK, Mall MA, Parsons DW, Dubsky S, Fouras A. Quantification of heterogeneity in lung disease with image-based pulmonary function testing. Scientific Reports. 6: 29438. PMID 27461961 DOI: 10.1038/Srep29438 |
0.38 |
|
| 2016 |
Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O'Neal WK, Boucher RC. Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunology. PMID 27435107 DOI: 10.1038/Mi.2016.63 |
0.374 |
|
| 2016 |
Button B, Anderson WH, Boucher RC. Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic Phenotype. Annals of the American Thoracic Society. 13: S156-62. PMID 27115951 DOI: 10.1513/Annalsats.201507-455Kv |
0.401 |
|
| 2016 |
Pattison S, Oram L, Johnston E, Lavelle G, Murray M, McElvaney N, Muhlebach M, Boucher R, Crockard M, Tunney M, Elborn J. 115 Prevalence of respiratory viruses in CF patients when clinically stable and during pulmonary exacerbation Journal of Cystic Fibrosis. 15: S80. DOI: 10.1016/S1569-1993(16)30353-8 |
0.365 |
|
| 2015 |
Boucher RC. On the Pathogenesis of Acute Exacerbations of Mucoobstructive Lung Diseases. Annals of the American Thoracic Society. 12: S160-3. PMID 26595733 DOI: 10.1513/Annalsats.201507-460Aw |
0.378 |
|
| 2015 |
Lubamba BA, Jones LC, O'Neal WK, Boucher RC, Ribeiro CM. X-Box Binding Protein 1 Modulates Innate Immune Responses of Cystic Fibrosis Alveolar Macrophages. American Journal of Respiratory and Critical Care Medicine. PMID 26331676 DOI: 10.1164/Rccm.201504-0657Oc |
0.358 |
|
| 2015 |
Saini Y, Wilkinson KJ, Terrell KA, Burns KA, Livraghi-Butrico A, Doerschuk CM, O'Neal WK, Boucher RC. Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses. American Journal of Respiratory Cell and Molecular Biology. PMID 26121027 DOI: 10.1165/Rcmb.2014-0111Oc |
0.391 |
|
| 2015 |
Ghosh A, Boucher RC, Tarran R. Airway hydration and COPD. Cellular and Molecular Life Sciences : Cmls. 72: 3637-52. PMID 26068443 DOI: 10.1007/S00018-015-1946-7 |
0.378 |
|
| 2015 |
Bennett WD, Wu J, Fuller F, Balcazar JR, Zeman KL, Duckworth H, Donn KH, O'Riordan TG, Boucher RC, Donaldson SH. Duration of action of hypertonic saline on mucociliary clearance in the normal lung. Journal of Applied Physiology (Bethesda, Md. : 1985). 118: 1483-90. PMID 25911685 DOI: 10.1152/Japplphysiol.00404.2014 |
0.374 |
|
| 2015 |
Anderson WH, Coakley RD, Button B, Henderson AG, Zeman KL, Alexis NE, Peden DB, Lazarowski ER, Davis CW, Bailey S, Fuller F, Almond M, Qaqish B, Bordonali E, Rubinstein M, ... ... Boucher RC, et al. The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis. American Journal of Respiratory and Critical Care Medicine. 192: 182-90. PMID 25909230 DOI: 10.1164/Rccm.201412-2230Oc |
0.499 |
|
| 2015 |
Esther CR, Coakley RD, Henderson AG, Zhou YH, Wright FA, Boucher RC. Metabolomic evaluation of neutrophilic airway inflammation in cystic fibrosis. Chest. PMID 25611918 DOI: 10.1378/Chest.14-1800 |
0.401 |
|
| 2014 |
Saini Y, Dang H, Livraghi-Butrico A, Kelly EJ, Jones LC, O'Neal WK, Boucher RC. Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration. Bmc Genomics. 15: 726. PMID 25204199 DOI: 10.1186/1471-2164-15-726 |
0.419 |
|
| 2014 |
Schwab U, Abdullah LH, Perlmutt OS, Albert D, Davis CW, Arnold RR, Yankaskas JR, Gilligan P, Neubauer H, Randell SH, Boucher RC. Localization of Burkholderia cepacia complex bacteria in cystic fibrosis lungs and interactions with Pseudomonas aeruginosa in hypoxic mucus. Infection and Immunity. 82: 4729-45. PMID 25156735 DOI: 10.1128/Iai.01876-14 |
0.403 |
|
| 2014 |
Morgan KS, Donnelley M, Farrow N, Fouras A, Yagi N, Suzuki Y, Takeuchi A, Uesugi K, Boucher RC, Siu KKW, Parsons DW. In vivo x-ray imaging reveals improved airway surface hydration after a therapy designed for cystic fibrosis American Journal of Respiratory and Critical Care Medicine. 190: 469-471. PMID 25127306 DOI: 10.1164/Rccm.201405-0855Le |
0.304 |
|
| 2014 |
Cholon DM, Quinney NL, Fulcher ML, Esther CR, Das J, Dokholyan NV, Randell SH, Boucher RC, Gentzsch M. Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis. Science Translational Medicine. 6: 246ra96. PMID 25101886 DOI: 10.1126/Scitranslmed.3008680 |
0.393 |
|
| 2014 |
Henderson AG, Ehre C, Button B, Abdullah LH, Cai LH, Leigh MW, DeMaria GC, Matsui H, Donaldson SH, Davis CW, Sheehan JK, Boucher RC, Kesimer M. Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure. The Journal of Clinical Investigation. 124: 3047-60. PMID 24892808 DOI: 10.1172/Jci73469 |
0.64 |
|
| 2014 |
Hill DB, Vasquez PA, Mellnik J, McKinley SA, Vose A, Mu F, Henderson AG, Donaldson SH, Alexis NE, Boucher RC, Forest MG. A biophysical basis for mucus solids concentration as a candidate biomarker for airways disease. Plos One. 9: e87681. PMID 24558372 DOI: 10.1371/Journal.Pone.0087681 |
0.402 |
|
| 2014 |
Donnelley M, Morgan KS, Siu KK, Farrow NR, Stahr CS, Boucher RC, Fouras A, Parsons DW. Non-invasive airway health assessment: synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo. Scientific Reports. 4: 3689. PMID 24418935 DOI: 10.1038/Srep03689 |
0.336 |
|
| 2014 |
Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, ... ... Boucher RC, et al. Muc5b is required for airway defence. Nature. 505: 412-6. PMID 24317696 DOI: 10.1038/Nature12807 |
0.423 |
|
| 2014 |
Bove PF, Dang H, Cheluvaraju C, Jones LC, Liu X, O'Neal WK, Randell SH, Schlegel R, Boucher RC. Breaking the in vitro alveolar type II cell proliferation barrier while retaining ion transport properties. American Journal of Respiratory Cell and Molecular Biology. 50: 767-76. PMID 24191670 DOI: 10.1165/Rcmb.2013-0071Oc |
0.387 |
|
| 2014 |
Esther CR, Boucher RC, Johnson MR, Ansede JH, Donn KH, O'Riordan TG, Ghio AJ, Hirsh AJ. Airway drug pharmacokinetics via analysis of exhaled breath condensate. Pulmonary Pharmacology & Therapeutics. 27: 76-82. PMID 23932897 DOI: 10.1016/J.Pupt.2013.07.009 |
0.329 |
|
| 2014 |
O'Riordan TG, Donn KH, Hodsman P, Ansede JH, Newcomb T, Lewis SA, Flitter WD, White VS, Johnson MR, Montgomery AB, Warnock DG, Boucher RC. Acute hyperkalemia associated with inhalation of a potent ENaC antagonist: Phase 1 trial of GS-9411. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 27: 200-8. PMID 23905576 DOI: 10.1089/Jamp.2013.1037 |
0.347 |
|
| 2014 |
Mall MA, Boucher RC. Pathophysiology of cystic fibrosis lung disease European Respiratory Monograph. 64: 1-13. DOI: 10.1183/1025448X.10008513 |
0.394 |
|
| 2014 |
Donnelley M, Morgan KS, Siu KKW, Farrow NR, Stahr CS, Boucher RC, Fouras A, Parsons DW. Erratum: CORRIGENDUM: Non-invasive airway health assessment: Synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo Scientific Reports. 4. DOI: 10.1038/Srep05361 |
0.336 |
|
| 2014 |
Henderson A, Button B, Boucher R, Kesimer M. WS12.2 Mucins are abnormally concentrated in CF respiratory secretions: role in disease pathogenesis Journal of Cystic Fibrosis. 13: S25. DOI: 10.1016/S1569-1993(14)60077-1 |
0.378 |
|
| 2013 |
Okada SF, Ribeiro CM, Sesma JI, Seminario-Vidal L, Abdullah LH, van Heusden C, Lazarowski ER, Boucher RC. Inflammation promotes airway epithelial ATP release via calcium-dependent vesicular pathways. American Journal of Respiratory Cell and Molecular Biology. 49: 814-20. PMID 23763446 DOI: 10.1165/Rcmb.2012-0493Oc |
0.478 |
|
| 2013 |
Button B, Okada SF, Frederick CB, Thelin WR, Boucher RC. Mechanosensitive ATP release maintains proper mucus hydration of airways. Science Signaling. 6: ra46. PMID 23757023 DOI: 10.1126/Scisignal.2003755 |
0.483 |
|
| 2013 |
Graeber SY, Zhou-Suckow Z, Schatterny J, Hirtz S, Boucher RC, Mall MA. Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease. American Journal of Respiratory Cell and Molecular Biology. 49: 410-7. PMID 23590312 DOI: 10.1165/Rcmb.2013-0050Oc |
0.424 |
|
| 2013 |
Garcia GJ, Boucher RC, Elston TC. Biophysical model of ion transport across human respiratory epithelia allows quantification of ion permeabilities. Biophysical Journal. 104: 716-26. PMID 23442922 DOI: 10.1016/J.Bpj.2012.12.040 |
0.379 |
|
| 2013 |
Morgan KS, Donnelley M, Paganin DM, Fouras A, Yagi N, Suzuki Y, Takeuchi A, Uesugi K, Boucher RC, Parsons DW, Siu KK. Measuring airway surface liquid depth in ex vivo mouse airways by x-ray imaging for the assessment of cystic fibrosis airway therapies. Plos One. 8: e55822. PMID 23383288 DOI: 10.1371/Journal.Pone.0055822 |
0.425 |
|
| 2013 |
Livraghi-Butrico A, Kelly EJ, Wilkinson KJ, Rogers TD, Gilmore RC, Harkema JR, Randell SH, Boucher RC, O'Neal WK, Grubb BR. Loss of Cftr function exacerbates the phenotype of Na(+) hyperabsorption in murine airways. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L469-80. PMID 23377346 DOI: 10.1152/Ajplung.00150.2012 |
0.452 |
|
| 2013 |
Esther CR, Olsen BM, Lin FC, Fine J, Boucher RC. Exhaled breath condensate adenosine tracks lung function changes in cystic fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L504-9. PMID 23355385 DOI: 10.1152/Ajplung.00344.2012 |
0.387 |
|
| 2013 |
Tunney MM, Einarsson GG, Wei L, Drain M, Klem ER, Cardwell C, Ennis M, Boucher RC, Wolfgang MC, Elborn JS. Lung microbiota and bacterial abundance in patients with bronchiectasis when clinically stable and during exacerbation. American Journal of Respiratory and Critical Care Medicine. 187: 1118-26. PMID 23348972 DOI: 10.1164/Rccm.201210-1937Oc |
0.355 |
|
| 2012 |
Fodor AA, Klem ER, Gilpin DF, Elborn JS, Boucher RC, Tunney MM, Wolfgang MC. The adult cystic fibrosis airway microbiota is stable over time and infection type, and highly resilient to antibiotic treatment of exacerbations. Plos One. 7: e45001. PMID 23049765 DOI: 10.1371/Journal.Pone.0045001 |
0.415 |
|
| 2012 |
Ehre C, Worthington EN, Liesman RM, Grubb BR, Barbier D, O'Neal WK, Sallenave JM, Pickles RJ, Boucher RC. Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs Proceedings of the National Academy of Sciences of the United States of America. 109: 16528-16533. PMID 23012413 DOI: 10.1073/Pnas.1206552109 |
0.435 |
|
| 2012 |
Button B, Cai LH, Ehre C, Kesimer M, Hill DB, Sheehan JK, Boucher RC, Rubinstein M. A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science (New York, N.Y.). 337: 937-41. PMID 22923574 DOI: 10.1126/Science.1223012 |
0.65 |
|
| 2012 |
Yu D, Thelin WR, Rogers TD, Jackson Stutts M, Randell SH, Grubb BR, Boucher RC. Regional differences in rat conjunctival ion transport activities American Journal of Physiology - Cell Physiology. 303: C767-C780. PMID 22814399 DOI: 10.1152/Ajpcell.00195.2012 |
0.354 |
|
| 2012 |
Livraghi-Butrico A, Kelly EJ, Klem ER, Dang H, Wolfgang MC, Boucher RC, Randell SH, O'Neal WK. Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation. Mucosal Immunology. 5: 397-408. PMID 22419116 DOI: 10.1038/Mi.2012.17 |
0.383 |
|
| 2012 |
Livraghi-Butrico A, Grubb BR, Kelly EJ, Wilkinson KJ, Yang H, Geiser M, Randell SH, Boucher RC, O'Neal WK. Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction. Physiological Genomics. 44: 470-84. PMID 22395316 DOI: 10.1152/Physiolgenomics.00185.2011 |
0.417 |
|
| 2012 |
Han MK, Huang YJ, Lipuma JJ, Boushey HA, Boucher RC, Cookson WO, Curtis JL, Erb-Downward J, Lynch SV, Sethi S, Toews GB, Young VB, Wolfgang MC, Huffnagle GB, Martinez FJ. Significance of the microbiome in obstructive lung disease. Thorax. 67: 456-63. PMID 22318161 DOI: 10.1136/Thoraxjnl-2011-201183 |
0.411 |
|
| 2012 |
Ramsey BW, Banks-Schlegel S, Accurso FJ, Boucher RC, Cutting GR, Engelhardt JF, Guggino WB, Karp CL, Knowles MR, Kolls JK, LiPuma JJ, Lynch S, McCray PB, Rubenstein RC, Singh PK, et al. Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. American Journal of Respiratory and Critical Care Medicine. 185: 887-92. PMID 22312017 DOI: 10.1164/Rccm.201111-2068Ws |
0.43 |
|
| 2012 |
Jones LC, Moussa L, Fulcher ML, Zhu Y, Hudson EJ, O'Neal WK, Randell SH, Lazarowski ER, Boucher RC, Kreda SM. VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cells. The Journal of Physiology. 590: 545-62. PMID 22144578 DOI: 10.1113/Jphysiol.2011.222091 |
0.476 |
|
| 2012 |
Grubb BR, O'Neal WK, Ostrowski LE, Kreda SM, Button B, Boucher RC. Transgenic hCFTR expression fails to correct β -ENaC mouse lung disease American Journal of Physiology - Lung Cellular and Molecular Physiology. 302: 238-247. PMID 22003093 DOI: 10.1152/Ajplung.00083.2011 |
0.415 |
|
| 2012 |
Clunes LA, Davies CM, Coakley RD, Aleksandrov AA, Henderson AG, Zeman KL, Worthington EN, Gentzsch M, Kreda SM, Cholon D, Bennett WD, Riordan JR, Boucher RC, Tarran R. Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 533-45. PMID 21990373 DOI: 10.1096/Fj.11-192377 |
0.399 |
|
| 2012 |
Oldenburg AL, Chhetri RK, Button BM, Hill DB, Boucher RC. Dynamic imaging of in vitro human airway epithelium using optical coherence tomography Biomedical Optics, Biomed 2012. DOI: 10.1364/Biomed.2012.Btu4B.6 |
0.38 |
|
| 2011 |
Seminario-Vidal L, Okada SF, Sesma JI, Kreda SM, van Heusden CA, Zhu Y, Jones LC, O'Neal WK, Penuela S, Laird DW, Boucher RC, Lazarowski ER. Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia. The Journal of Biological Chemistry. 286: 26277-86. PMID 21606493 DOI: 10.1074/Jbc.M111.260562 |
0.382 |
|
| 2011 |
Garcia GJ, Picher M, Zuo P, Okada SF, Lazarowski ER, Button B, Boucher RC, Elston TC. Computational model for the regulation of extracellular ATP and adenosine in airway epithelia. Sub-Cellular Biochemistry. 55: 51-74. PMID 21560044 DOI: 10.1007/978-94-007-1217-1_3 |
0.415 |
|
| 2011 |
Clunes MT, Boucher RC. Introduction to section I: overview of approaches to study cystic fibrosis pathophysiology. Methods in Molecular Biology (Clifton, N.J.). 742: 3-14. PMID 21547723 DOI: 10.1007/978-1-61779-120-8_1 |
0.427 |
|
| 2011 |
Boucher RC. Idiopathic pulmonary fibrosis--a sticky business. The New England Journal of Medicine. 364: 1560-1. PMID 21506745 DOI: 10.1056/Nejme1014191 |
0.393 |
|
| 2011 |
Esther CR, Lazaar AL, Bordonali E, Qaqish B, Boucher RC. Elevated airway purines in COPD. Chest. 140: 954-60. PMID 21454402 DOI: 10.1378/Chest.10-2471 |
0.387 |
|
| 2011 |
Tunney MM, Klem ER, Fodor AA, Gilpin DF, Moriarty TF, McGrath SJ, Muhlebach MS, Boucher RC, Cardwell C, Doering G, Elborn JS, Wolfgang MC. Use of culture and molecular analysis to determine the effect of antibiotic treatment on microbial community diversity and abundance during exacerbation in patients with cystic fibrosis. Thorax. 66: 579-84. PMID 21270069 DOI: 10.1136/Thx.2010.137281 |
0.357 |
|
| 2011 |
Stressmann FA, Rogers GB, Klem ER, Lilley AK, Donaldson SH, Daniels TW, Carroll MP, Patel N, Forbes B, Boucher RC, Wolfgang MC, Bruce KD. Analysis of the bacterial communities present in lungs of patients with cystic fibrosis from American and British centers. Journal of Clinical Microbiology. 49: 281-91. PMID 21068277 DOI: 10.1128/Jcm.01650-10 |
0.344 |
|
| 2011 |
Okada SF, Zhang L, Kreda SM, Abdullah LH, Davis CW, Pickles RJ, Lazarowski ER, Boucher RC. Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 45: 253-60. PMID 20935191 DOI: 10.1165/Rcmb.2010-0253Oc |
0.38 |
|
| 2010 |
Bove PF, Grubb BR, Okada SF, Ribeiro CMP, Rogers TD, Randell SH, O'Neal WK, Boucher RC. Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling Journal of Biological Chemistry. 285: 34939-34949. PMID 20801871 DOI: 10.1074/Jbc.M110.162933 |
0.421 |
|
| 2010 |
Gentzsch M, Dang H, Dang Y, Garcia-Caballero A, Suchindran H, Boucher RC, Stutts MJ. The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel. The Journal of Biological Chemistry. 285: 32227-32. PMID 20709758 DOI: 10.1074/Jbc.M110.155259 |
0.485 |
|
| 2010 |
Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA, Schubert SC, Schultz C, O'Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC. Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice. The Journal of Biological Chemistry. 285: 26945-55. PMID 20566636 DOI: 10.1074/Jbc.M110.151803 |
0.452 |
|
| 2010 |
Goralski JL, Boucher RC, Button B. Osmolytes and ion transport modulators: new strategies for airway surface rehydration. Current Opinion in Pharmacology. 10: 294-9. PMID 20439165 DOI: 10.1016/J.Coph.2010.04.003 |
0.405 |
|
| 2010 |
Kreda SM, Seminario-Vidal L, van Heusden CA, O'Neal W, Jones L, Boucher RC, Lazarowski ER. Receptor-promoted exocytosis of airway epithelial mucin granules containing a spectrum of adenine nucleotides. The Journal of Physiology. 588: 2255-67. PMID 20421285 DOI: 10.1113/Jphysiol.2009.186643 |
0.352 |
|
| 2009 |
Zhang L, Button B, Gabriel SE, Burkett S, Yan Y, Skiadopoulos MH, Dang YL, Vogel LN, McKay T, Mengos A, Boucher RC, Collins PL, Pickles RJ. CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium. Plos Biology. 7: e1000155. PMID 19621064 DOI: 10.1371/Journal.Pbio.1000155 |
0.493 |
|
| 2009 |
Ribeiro CM, Hurd H, Wu Y, Martino ME, Jones L, Brighton B, Boucher RC, O'Neal WK. Azithromycin treatment alters gene expression in inflammatory, lipid metabolism, and cell cycle pathways in well-differentiated human airway epithelia. Plos One. 4: e5806. PMID 19503797 DOI: 10.1371/Journal.Pone.0005806 |
0.346 |
|
| 2009 |
Seminario-Vidal L, Kreda S, Jones L, O'Neal W, Trejo J, Boucher RC, Lazarowski ER. Thrombin promotes release of ATP from lung epithelial cells through coordinated activation of rho- and Ca2+-dependent signaling pathways. The Journal of Biological Chemistry. 284: 20638-48. PMID 19439413 DOI: 10.1074/Jbc.M109.004762 |
0.355 |
|
| 2009 |
Rock JR, O'Neal WK, Gabriel SE, Randell SH, Harfe BD, Boucher RC, Grubb BR. Transmembrane protein 16A (TMEM16A) is a Ca2+ -regulated Cl- secretory channel in mouse airways Journal of Biological Chemistry. 284: 14875-14880. PMID 19363029 DOI: 10.1074/Jbc.C109.000869 |
0.424 |
|
| 2009 |
Grubb BR, Rogers TD, Boucher RC, Ostrowski LE. Ion transport across CF and normal murine olfactory and ciliated epithelium American Journal of Physiology - Cell Physiology. 296: C1301-C1309. PMID 19321738 DOI: 10.1152/Ajpcell.00578.2008 |
0.439 |
|
| 2009 |
Esther CR, Boysen G, Olsen BM, Collins LB, Ghio AJ, Swenberg JW, Boucher RC. Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L987-93. PMID 19304910 DOI: 10.1152/Ajplung.90512.2008 |
0.383 |
|
| 2009 |
Livraghi A, Grubb BR, Hudson EJ, Wilkinson KJ, Sheehan JK, Mall MA, O'Neal WK, Boucher RC, Randell SH. Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment. Journal of Immunology (Baltimore, Md. : 1950). 182: 4357-67. PMID 19299736 DOI: 10.4049/Jimmunol.0802557 |
0.359 |
|
| 2009 |
Zhou Z, Harm M, Treis D, Schubert S, Schatterny J, Hirtz S, Duerr J, Hirsh A, Ross Johnson M, Boucher R, Mall M. The novel long acting ENaC blocker P643 has therapeutic effects in chronic cystic fibrosis-like lung disease in mice Journal of Cystic Fibrosis. 8: S26. DOI: 10.1016/S1569-1993(09)60106-5 |
0.372 |
|
| 2008 |
Zhou Z, Treis D, Schubert SC, Harm M, Schatterny J, Hirtz S, Duerr J, Boucher RC, Mall MA. Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice. American Journal of Respiratory and Critical Care Medicine. 178: 1245-56. PMID 18849497 DOI: 10.1164/Rccm.200803-442Oc |
0.447 |
|
| 2008 |
Zuo P, Picher M, Okada SF, Lazarowski ER, Button B, Boucher RC, Elston TC. Mathematical model of nucleotide regulation on airway epithelia. Implications for airway homeostasis. The Journal of Biological Chemistry. 283: 26805-19. PMID 18662982 DOI: 10.1074/Jbc.M801516200 |
0.376 |
|
| 2008 |
Siu KKW, Morgan KS, Paganin DM, Boucher RC, Uesugi K, Yagi N, Parsons DW. Phase contrast X-ray imaging for the non-invasive detection of airway surfaces and lumen characteristics in mouse models of airway disease European Journal of Radiology. 68: 22-26. PMID 18599234 DOI: 10.1016/J.Ejrad.2008.04.029 |
0.398 |
|
| 2008 |
Button B, Boucher RC. Role of mechanical stress in regulating airway surface hydration and mucus clearance rates. Respiratory Physiology & Neurobiology. 163: 189-201. PMID 18585484 DOI: 10.1016/J.Resp.2008.04.020 |
0.414 |
|
| 2008 |
Clunes MT, Boucher RC. Front-runners for pharmacotherapeutic correction of the airway ion transport defect in cystic fibrosis Current Opinion in Pharmacology. 8: 292-299. PMID 18468487 DOI: 10.1016/J.Coph.2008.04.006 |
0.475 |
|
| 2008 |
Tunney MM, Field TR, Moriarty TF, Patrick S, Doering G, Muhlebach MS, Wolfgang MC, Boucher R, Gilpin DF, McDowell A, Elborn JS. Detection of anaerobic bacteria in high numbers in sputum from patients with cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 177: 995-1001. PMID 18263800 DOI: 10.1164/Rccm.200708-1151Oc |
0.381 |
|
| 2008 |
Esther CR, Alexis NE, Clas ML, Lazarowski ER, Donaldson SH, Ribeiro CM, Moore CG, Davis SD, Boucher RC. Extracellular purines are biomarkers of neutrophilic airway inflammation. The European Respiratory Journal. 31: 949-56. PMID 18256064 DOI: 10.1183/09031936.00089807 |
0.346 |
|
| 2008 |
Hirsh AJ, Zhang J, Zamurs A, Fleegle J, Thelin WR, Caldwell RA, Sabater JR, Abraham WM, Donowitz M, Cha B, Johnson KB, St George JA, Johnson MR, Boucher RC. Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease. The Journal of Pharmacology and Experimental Therapeutics. 325: 77-88. PMID 18218832 DOI: 10.1124/Jpet.107.130443 |
0.433 |
|
| 2008 |
Mall MA, Harkema JR, Trojanek JB, Treis D, Livraghi A, Schubert S, Zhou Z, Kreda SM, Tilley SL, Hudson EJ, O'Neal WK, Boucher RC. Development of chronic bronchitis and emphysema in beta-epithelial Na+ channel-overexpressing mice. American Journal of Respiratory and Critical Care Medicine. 177: 730-42. PMID 18079494 DOI: 10.1164/Rccm.200708-1233Oc |
0.355 |
|
| 2008 |
Livraghi A, Mall M, Paradiso AM, Boucher RC, Ribeiro CM. Modelling dysregulated Na+ absorption in airway epithelial cells with mucosal nystatin treatment. American Journal of Respiratory Cell and Molecular Biology. 38: 423-34. PMID 17989361 DOI: 10.1165/Rcmb.2007-0177Oc |
0.402 |
|
| 2008 |
Tunney M, Klem E, Moriarty T, Gilpin D, Boucher R, Elborn J, Doring G, Wolfgang M. Comparison of culture and molecular methods for detection and quantitation of aerobic and anaerobic bacteria in sputum from cystic fibrosis patients Journal of Cystic Fibrosis. 7: S41. DOI: 10.1016/S1569-1993(08)60156-3 |
0.313 |
|
| 2008 |
Treis D, Zhou Z, Schubert S, Harm M, Schatterny J, Hirtz S, Duerr J, Boucher R, Mall M. Preventive but not late amiloride therapy reduces morbidity and mortality of cystic fibrosis-like lung disease in mice Journal of Cystic Fibrosis. 7: S23. DOI: 10.1016/S1569-1993(08)60088-0 |
0.322 |
|
| 2007 |
Clunes MT, Boucher RC. Cystic Fibrosis: The Mechanisms of Pathogenesis of an Inherited Lung Disorder. Drug Discovery Today. Disease Mechanisms. 4: 63-72. PMID 18560471 DOI: 10.1016/J.Ddmec.2007.09.001 |
0.453 |
|
| 2007 |
Donaldson SH, Boucher RC. Sodium channels and cystic fibrosis. Chest. 132: 1631-6. PMID 17998363 DOI: 10.1378/chest.07-0288 |
0.333 |
|
| 2007 |
Hirsh AJ, Stonebraker JR, van Heusden CA, Lazarowski ER, Boucher RC, Picher M. Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases. Biochemistry. 46: 10373-83. PMID 17696452 DOI: 10.1021/Bi7009647 |
0.438 |
|
| 2007 |
Tarran R, Donaldson S, Boucher RC. Rationale for hypertonic saline therapy for cystic fibrosis lung disease. Seminars in Respiratory and Critical Care Medicine. 28: 295-302. PMID 17562499 DOI: 10.1055/S-2007-981650 |
0.476 |
|
| 2007 |
Boucher RC. Cystic fibrosis: a disease of vulnerability to airway surface dehydration. Trends in Molecular Medicine. 13: 231-40. PMID 17524805 DOI: 10.1016/j.molmed.2007.05.001 |
0.399 |
|
| 2007 |
Thelin WR, Boucher RC. The epithelium as a target for therapy in cystic fibrosis. Current Opinion in Pharmacology. 7: 290-5. PMID 17475561 DOI: 10.1016/J.Coph.2007.01.004 |
0.453 |
|
| 2007 |
Button B, Picher M, Boucher RC. Differential effects of cyclic and constant stress on ATP release and mucociliary transport by human airway epithelia. The Journal of Physiology. 580: 577-92. PMID 17317749 DOI: 10.1113/Jphysiol.2006.126086 |
0.478 |
|
| 2007 |
Boucher RC. Evidence for airway surface dehydration as the initiating event in CF airway disease. Journal of Internal Medicine. 261: 5-16. PMID 17222164 DOI: 10.1111/J.1365-2796.2006.01744.X |
0.457 |
|
| 2007 |
Boucher RC. Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annual Review of Medicine. 58: 157-70. PMID 17217330 DOI: 10.1146/Annurev.Med.58.071905.105316 |
0.481 |
|
| 2007 |
Winters SL, Davis CW, Boucher RC. Mechanosensitivity of mouse tracheal ciliary beat frequency: roles for Ca2+, purinergic signaling, tonicity, and viscosity. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L614-24. PMID 16963528 DOI: 10.1152/Ajplung.00288.2005 |
0.302 |
|
| 2006 |
Dejima K, Randell SH, Stutts MJ, Senior BA, Boucher RC. Potential role of abnormal ion transport in the pathogenesis of chronic sinusitis. Archives of Otolaryngology--Head & Neck Surgery. 132: 1352-62. PMID 17178948 DOI: 10.1001/Archotol.132.12.1352 |
0.377 |
|
| 2006 |
Matsui H, Wagner VE, Hill DB, Schwab UE, Rogers TD, Button B, Taylor RM, Superfine R, Rubinstein M, Iglewski BH, Boucher RC. A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms. Proceedings of the National Academy of Sciences of the United States of America. 103: 18131-6. PMID 17116883 DOI: 10.1073/Pnas.0606428103 |
0.578 |
|
| 2006 |
Muhlebach MS, MacDonald SL, Button B, Hubbard JJ, Turner ML, Boucher RC, Kilpatrick DC. Association between mannan-binding lectin and impaired lung function in cystic fibrosis may be age-dependent. Clinical and Experimental Immunology. 145: 302-7. PMID 16879250 DOI: 10.1111/J.1365-2249.2006.03151.X |
0.362 |
|
| 2006 |
Hirsh AJ, Molino BF, Zhang J, Astakhova N, Geiss WB, Sargent BJ, Swenson BD, Usyatinsky A, Wyle MJ, Boucher RC, Smith RT, Zamurs A, Johnson MR. Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis. Journal of Medicinal Chemistry. 49: 4098-115. PMID 16821771 DOI: 10.1021/Jm051134W |
0.301 |
|
| 2006 |
Okada SF, Nicholas RA, Kreda SM, Lazarowski ER, Boucher RC. Physiological regulation of ATP release at the apical surface of human airway epithelia. The Journal of Biological Chemistry. 281: 22992-3002. PMID 16754672 DOI: 10.1074/Jbc.M603019200 |
0.4 |
|
| 2006 |
Blouquit S, Regnier A, Dannhoffer L, Fermanian C, Naline E, Boucher R, Chinet T. Ion and Fluid Transport Properties of Small Airways in Cystic Fibrosis American Journal of Respiratory and Critical Care Medicine. 174: 299-305. PMID 16645176 DOI: 10.1164/Rccm.200506-987Oc |
0.462 |
|
| 2006 |
Tarran R, Trout L, Donaldson SH, Boucher RC. Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia. The Journal of General Physiology. 127: 591-604. PMID 16636206 DOI: 10.1085/Jgp.200509468 |
0.453 |
|
| 2006 |
Douillet CD, Robinson WP, Milano PM, Boucher RC, Rich PB. Nucleotides induce IL-6 release from human airway epithelia via P2Y2 and p38 MAPK-dependent pathways. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L734-46. PMID 16632518 DOI: 10.1152/Ajplung.00389.2005 |
0.319 |
|
| 2006 |
Randell SH, Boucher RC. Effective mucus clearance is essential for respiratory health. American Journal of Respiratory Cell and Molecular Biology. 35: 20-8. PMID 16528010 DOI: 10.1165/Rcmb.2006-0082Sf |
0.46 |
|
| 2006 |
Tarran R, Button B, Boucher RC. Regulation of normal and cystic fibrosis airway surface liquid volume by phasic shear stress. Annual Review of Physiology. 68: 543-61. PMID 16460283 DOI: 10.1146/Annurev.Physiol.68.072304.112754 |
0.46 |
|
| 2006 |
Yoon SS, Coakley R, Lau GW, Lymar SV, Gaston B, Karabulut AC, Hennigan RF, Hwang SH, Buettner G, Schurr MJ, Mortensen JE, Burns JL, Speert D, Boucher RC, Hassett DJ. Anaerobic killing of mucoid Pseudomonas aeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions. The Journal of Clinical Investigation. 116: 436-46. PMID 16440061 DOI: 10.1172/Jci24684 |
0.446 |
|
| 2006 |
Donaldson SH, Bennett WD, Zeman KL, Knowles MR, Tarran R, Boucher RC. Mucus clearance and lung function in cystic fibrosis with hypertonic saline. The New England Journal of Medicine. 354: 241-50. PMID 16421365 DOI: 10.1056/Nejmoa043891 |
0.43 |
|
| 2006 |
Grubb BR, Gabriel SE, Mengos A, Gentzsch M, Randell SH, Van Heeckeren AM, Knowles MR, Drumm ML, Riordan JR, Boucher RC. SERCA pump inhibitors do not correct biosynthetic arrest of ΔF508 CFTR in cystic fibrosis American Journal of Respiratory Cell and Molecular Biology. 34: 355-363. PMID 16284361 DOI: 10.1165/Rcmb.2005-0286Oc |
0.45 |
|
| 2006 |
Grubb BR, Rogers TD, Diggs PC, Boucher RC, Ostrowski LE. Culture of murine nasal epithelia: model for cystic fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L270-7. PMID 16155086 DOI: 10.1152/Ajplung.00249.2005 |
0.465 |
|
| 2006 |
Muhlebach M, Button B, Leigh M, Boucher R. 205 Serum biomarkers in CF lung disease Journal of Cystic Fibrosis. 5: S48. DOI: 10.1016/S1569-1993(06)80187-6 |
0.375 |
|
| 2006 |
Stressmann A, Rogers G, Carroll M, Donaldson S, Boucher R, Bruce K. 66 Bacterial diversity in the Cystic Fibrosis lung: geographical differences in community composition and distribution Journal of Cystic Fibrosis. 5: S15. DOI: 10.1016/S1569-1993(06)80057-3 |
0.336 |
|
| 2005 |
Tarran R, Button B, Picher M, Paradiso AM, Ribeiro CM, Lazarowski ER, Zhang L, Collins PL, Pickles RJ, Fredberg JJ, Boucher RC. Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections. The Journal of Biological Chemistry. 280: 35751-9. PMID 16087672 DOI: 10.1074/Jbc.M505832200 |
0.632 |
|
| 2005 |
Geary C, Akinbi H, Korfhagen T, Fabre JE, Boucher R, Rice W. Increased susceptibility of purinergic receptor-deficient mice to lung infection with Pseudomonas aeruginosa. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L890-5. PMID 16024720 DOI: 10.1152/Ajplung.00428.2004 |
0.367 |
|
| 2005 |
Matsui H, Verghese MW, Kesimer M, Schwab UE, Randell SH, Sheehan JK, Grubb BR, Boucher RC. Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces Journal of Immunology. 175: 1090-1099. PMID 16002710 DOI: 10.4049/Jimmunol.175.2.1090 |
0.468 |
|
| 2005 |
Highsmith WE, Friedman KJ, Burch LH, Spock A, Silverman LM, Boucher RC, Knowles MR. A CFTR mutation (D1152H) in a family with mild lung disease and normal sweat chlorides. Clinical Genetics. 68: 88-90. PMID 15952991 DOI: 10.1111/J.1399-0004.2005.00459.X |
0.698 |
|
| 2005 |
Ribeiro CM, Paradiso AM, Schwab U, Perez-Vilar J, Jones L, O'neal W, Boucher RC. Chronic airway infection/inflammation induces a Ca2+i-dependent hyperinflammatory response in human cystic fibrosis airway epithelia. The Journal of Biological Chemistry. 280: 17798-806. PMID 15746099 DOI: 10.1074/Jbc.M410618200 |
0.422 |
|
| 2005 |
Kreda SM, Mall M, Mengos A, Rochelle L, Yankaskas J, Riordan JR, Boucher RC. Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. Molecular Biology of the Cell. 16: 2154-67. PMID 15716351 DOI: 10.1091/Mbc.E04-11-1010 |
0.462 |
|
| 2005 |
Ribeiro CM, Paradiso AM, Carew MA, Shears SB, Boucher RC. Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia. The Journal of Biological Chemistry. 280: 10202-9. PMID 15647273 DOI: 10.1074/Jbc.M410617200 |
0.387 |
|
| 2005 |
Caldwell RA, Boucher RC, Stutts MJ. Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport American Journal of Physiology - Lung Cellular and Molecular Physiology. 288: L813-L819. PMID 15640288 DOI: 10.1152/Ajplung.00435.2004 |
0.414 |
|
| 2005 |
Tilley SL, Boucher RC. A1 antagonism in asthma: better than coffee? The Journal of Clinical Investigation. 115: 13-6. PMID 15630434 DOI: 10.1172/Jci24009 |
0.328 |
|
| 2005 |
Perez-Vilar J, Boucher RC. Reevaluating gel-forming mucins' roles in cystic fibrosis lung disease. Free Radical Biology & Medicine. 37: 1564-77. PMID 15477008 DOI: 10.1016/J.Freeradbiomed.2004.07.027 |
0.435 |
|
| 2005 |
Douillet CD, Robinson WP, Zarzaur BL, Lazarowski ER, Boucher RC, Rich PB. Mechanical ventilation alters airway nucleotides and purinoceptors in lung and extrapulmonary organs. American Journal of Respiratory Cell and Molecular Biology. 32: 52-8. PMID 15388514 DOI: 10.1165/Rcmb.2004-0177Oc |
0.37 |
|
| 2004 |
Stonebraker JR, Wagner D, Lefensty RW, Burns K, Gendler SJ, Bergelson JM, Boucher RC, O'Neal WK, Pickles RJ. Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: role for tethered mucins as barriers to lumenal infection. Journal of Virology. 78: 13755-68. PMID 15564484 DOI: 10.1128/Jvi.78.24.13755-13768.2004 |
0.382 |
|
| 2004 |
Okada SF, O'Neal WK, Huang P, Nicholas RA, Ostrowski LE, Craigen WJ, Lazarowski ER, Boucher RC. Voltage-dependent anion channel-1 (VDAC-1) contributes to ATP release and cell volume regulation in murine cells. The Journal of General Physiology. 124: 513-26. PMID 15477379 DOI: 10.1085/Jgp.200409154 |
0.374 |
|
| 2004 |
Hirsh AJ, Sabater JR, Zamurs A, Smith RT, Paradiso AM, Hopkins S, Abraham WM, Boucher RC. Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease. The Journal of Pharmacology and Experimental Therapeutics. 311: 929-38. PMID 15273255 DOI: 10.1124/Jpet.104.071886 |
0.463 |
|
| 2004 |
Lazarowski ER, Tarran R, Grubb BR, Van Heusden CA, Okada S, Boucher RC. Nucleotide release provides a mechanism for airway surface liquid homeostasis Journal of Biological Chemistry. 279: 36855-36864. PMID 15210701 DOI: 10.1074/Jbc.M405367200 |
0.306 |
|
| 2004 |
Mall M, Grubb BR, Harkema JR, O'Neal WK, Boucher RC. Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice Nature Medicine. 10: 487-493. PMID 15077107 DOI: 10.1038/Nm1028 |
0.495 |
|
| 2004 |
Picher M, Burch LH, Boucher RC. Metabolism of P2 receptor agonists in human airways: implications for mucociliary clearance and cystic fibrosis. The Journal of Biological Chemistry. 279: 20234-41. PMID 14993227 DOI: 10.1074/Jbc.M400305200 |
0.766 |
|
| 2004 |
Boucher RC. New concepts of the pathogenesis of cystic fibrosis lung disease. The European Respiratory Journal. 23: 146-58. PMID 14738247 DOI: 10.1183/09031936.03.00057003 |
0.49 |
|
| 2004 |
Mall M, Kreda SM, Mengos A, Jensen TJ, Hirtz S, Seydewitz HH, Yankaskas J, Kunzelmann K, Riordan JR, Boucher RC. The DeltaF508 mutation results in loss of CFTR function and mature protein in native human colon. Gastroenterology. 126: 32-41. PMID 14699484 DOI: 10.1053/J.Gastro.2003.10.049 |
0.349 |
|
| 2004 |
Grubb BR, Jones JH, Boucher RC. Mucociliary transport determined by in vivo microdialysis in the airways of normal and CF mice American Journal of Physiology - Lung Cellular and Molecular Physiology. 286: L588-L595. PMID 14633516 DOI: 10.1152/Ajplung.00302.2003 |
0.392 |
|
| 2004 |
Donaldson SH, Boucher RC. Update on pathogenesis of cystic fibrosis lung disease. Current Opinion in Pulmonary Medicine. 9: 486-91. PMID 14534400 DOI: 10.1097/00063198-200311000-00007 |
0.423 |
|
| 2004 |
Gray T, Coakley R, Hirsh A, Thornton D, Kirkham S, Koo JS, Burch L, Boucher R, Nettesheim P. Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1beta in human bronchial epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L320-30. PMID 14527933 DOI: 10.1152/Ajplung.00440.2002 |
0.699 |
|
| 2003 |
Coakley RD, Grubb BR, Paradiso AM, Gatzy JT, Johnson LG, Kreda SM, O'Neal WK, Boucher RC. Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium. Proceedings of the National Academy of Sciences of the United States of America. 100: 16083-8. PMID 14668433 DOI: 10.1073/Pnas.2634339100 |
0.714 |
|
| 2003 |
Rich PB, Douillet CD, Hurd H, Boucher RC. Effect of ventilatory rate on airway cytokine levels and lung injury. The Journal of Surgical Research. 113: 139-45. PMID 12943823 DOI: 10.1016/S0022-4804(03)00195-1 |
0.367 |
|
| 2003 |
Rich PB, Douillet CD, Mahler SA, Husain SA, Boucher RC. Adenosine triphosphate is released during injurious mechanical ventilation and contributes to lung edema. The Journal of Trauma. 55: 290-7. PMID 12913640 DOI: 10.1097/01.Ta.0000078882.11919.Af |
0.359 |
|
| 2003 |
Coyne CB, Gambling TM, Boucher RC, Carson JL, Johnson LG. Role of claudin interactions in airway tight junctional permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1166-78. PMID 12909588 DOI: 10.1152/Ajplung.00182.2003 |
0.69 |
|
| 2003 |
Coyne CB, Ribeiro CM, Boucher RC, Johnson LG. Acute mechanism of medium chain fatty acid-induced enhancement of airway epithelial permeability. The Journal of Pharmacology and Experimental Therapeutics. 305: 440-50. PMID 12606647 DOI: 10.1124/Jpet.102.047654 |
0.642 |
|
| 2003 |
Paradiso AM, Coakley RD, Boucher RC. Polarized distribution of HCO3- transport in human normal and cystic fibrosis nasal epithelia. The Journal of Physiology. 548: 203-18. PMID 12562898 DOI: 10.1113/Jphysiol.2002.034447 |
0.449 |
|
| 2003 |
Picher M, Burch LH, Hirsh AJ, Spychala J, Boucher RC. Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways. The Journal of Biological Chemistry. 278: 13468-79. PMID 12560324 DOI: 10.1074/Jbc.M300569200 |
0.731 |
|
| 2003 |
Picher M, Boucher RC. Human airway ecto-adenylate kinase. A mechanism to propagate ATP signaling on airway surfaces. The Journal of Biological Chemistry. 278: 11256-64. PMID 12551890 DOI: 10.1074/Jbc.M208071200 |
0.396 |
|
| 2003 |
Boucher RC. An overview of the pathogenesis of cystic fibrosis lung disease. Advanced Drug Delivery Reviews. 54: 1359-71. PMID 12458149 DOI: 10.1016/S0169-409X(02)00144-8 |
0.382 |
|
| 2003 |
Sood N, Bennett WD, Zeman K, Brown J, Foy C, Boucher RC, Knowles MR. Increasing concentration of inhaled saline with or without amiloride: effect on mucociliary clearance in normal subjects. American Journal of Respiratory and Critical Care Medicine. 167: 158-63. PMID 12411282 DOI: 10.1164/Rccm.200204-293Oc |
0.381 |
|
| 2002 |
Yoon SS, Hennigan RF, Hilliard GM, Ochsner UA, Parvatiyar K, Kamani MC, Allen HL, DeKievit TR, Gardner PR, Schwab U, Rowe JJ, Iglewski BH, McDermott TR, Mason RP, Wozniak DJ, ... ... Boucher RC, et al. Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Developmental Cell. 3: 593-603. PMID 12408810 DOI: 10.1016/S1534-5807(02)00295-2 |
0.374 |
|
| 2002 |
Collier DN, Anderson L, McKnight SL, Noah TL, Knowles M, Boucher R, Schwab U, Gilligan P, Pesci EC. A bacterial cell to cell signal in the lungs of cystic fibrosis patients. Fems Microbiology Letters. 215: 41-6. PMID 12393198 DOI: 10.1111/J.1574-6968.2002.Tb11367.X |
0.405 |
|
| 2002 |
Coyne CB, Vanhook MK, Gambling TM, Carson JL, Boucher RC, Johnson LG. Regulation of airway tight junctions by proinflammatory cytokines. Molecular Biology of the Cell. 13: 3218-34. PMID 12221127 DOI: 10.1091/Mbc.E02-03-0134 |
0.675 |
|
| 2002 |
Tarran R, Loewen ME, Paradiso AM, Olsen JC, Gray MA, Argent BE, Boucher RC, Gabriel SE. Regulation of murine airway surface liquid volume by CFTR and Ca2+-activated Cl- conductances. The Journal of General Physiology. 120: 407-18. PMID 12198094 DOI: 10.1085/Jgp.20028599 |
0.447 |
|
| 2002 |
Yerxa BR, Sabater JR, Davis CW, Stutts MJ, Lang-Furr M, Picher M, Jones AC, Cowlen M, Dougherty R, Boyer J, Abraham WM, Boucher RC. Pharmacology of INS37217 [P(1)-(uridine 5')-P(4)- (2'-deoxycytidine 5')tetraphosphate, tetrasodium salt], a next-generation P2Y(2) receptor agonist for the treatment of cystic fibrosis. The Journal of Pharmacology and Experimental Therapeutics. 302: 871-80. PMID 12183642 DOI: 10.1124/Jpet.102.035485 |
0.379 |
|
| 2002 |
Schwab U, Leigh M, Ribeiro C, Yankaskas J, Burns K, Gilligan P, Sokol P, Boucher R. Patterns of epithelial cell invasion by different species of the Burkholderia cepacia complex in well-differentiated human airway epithelia. Infection and Immunity. 70: 4547-55. PMID 12117967 DOI: 10.1128/Iai.70.8.4547-4555.2002 |
0.345 |
|
| 2002 |
Grubb BR, Chadburn JL, Boucher RC. In vivo microdialysis for determination of nasal liquid ion composition American Journal of Physiology - Cell Physiology. 282: C1423-C1431. PMID 11997257 DOI: 10.1152/Ajpcell.00612.2001 |
0.413 |
|
| 2002 |
Zhang L, Peeples ME, Boucher RC, Collins PL, Pickles RJ. Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. Journal of Virology. 76: 5654-66. PMID 11991994 DOI: 10.1128/Jvi.76.11.5654-5666.2002 |
0.42 |
|
| 2002 |
Tarran R, Boucher RC. Thin-film measurements of airway surface liquid volume/composition and mucus transport rates in vitro. Methods in Molecular Medicine. 70: 479-92. PMID 11917544 DOI: 10.1385/1-59259-187-6:479 |
0.318 |
|
| 2002 |
Knowles MR, Boucher RC. Mucus clearance as a primary innate defense mechanism for mammalian airways. The Journal of Clinical Investigation. 109: 571-7. PMID 11877463 DOI: 10.1172/Jci15217 |
0.445 |
|
| 2002 |
Zhang YJ, O'Neal WK, Randell SH, Blackburn K, Moyer MB, Boucher RC, Ostrowski LE. Identification of dynein heavy chain 7 as an inner arm component of human cilia that is synthesized but not assembled in a case of primary ciliary dyskinesia. The Journal of Biological Chemistry. 277: 17906-15. PMID 11877439 DOI: 10.1074/Jbc.M200348200 |
0.347 |
|
| 2002 |
Worlitzsch D, Tarran R, Ulrich M, Schwab U, Cekici A, Meyer KC, Birrer P, Bellon G, Berger J, Weiss T, Botzenhart K, Yankaskas JR, Randell S, Boucher RC, Döring G. Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. The Journal of Clinical Investigation. 109: 317-25. PMID 11827991 DOI: 10.1172/Jci13870 |
0.44 |
|
| 2002 |
Donaldson SH, Picher M, Boucher RC. Secreted and cell-associated adenylate kinase and nucleoside diphosphokinase contribute to extracellular nucleotide metabolism on human airway surfaces. American Journal of Respiratory Cell and Molecular Biology. 26: 209-15. PMID 11804872 DOI: 10.1165/Ajrcmb.26.2.4650 |
0.395 |
|
| 2002 |
Caldwell RA, Grubb BR, Tarran R, Boucher RC, Knowles MR, Barker PM. In vivo airway surface liquid Cl- analysis with solid-state electrodes. The Journal of General Physiology. 119: 3-14. PMID 11773234 DOI: 10.1085/Jgp.119.1.3 |
0.4 |
|
| 2002 |
Donaldson SH, Hirsh A, Li DC, Holloway G, Chao J, Boucher RC, Gabriel SE. Regulation of the epithelial sodium channel by serine proteases in human airways. The Journal of Biological Chemistry. 277: 8338-45. PMID 11756432 DOI: 10.1074/Jbc.M105044200 |
0.408 |
|
| 2002 |
Rich PB, Douillet C, Hurd H, Boucher RC. RESPIRATORY RATE AFFECTS PRO-INFLAMMATORY PULMONARY CYTOKINES AND LUNG EDEMA DURING LARGE-VOLUME VENTILATION Critical Care Medicine. 30: A31. DOI: 10.1097/00003246-200212001-00108 |
0.369 |
|
| 2001 |
Huang P, Lazarowski ER, Tarran R, Milgram SL, Boucher RC, Stutts MJ. Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 14120-5. PMID 11707576 DOI: 10.1073/Pnas.241318498 |
0.399 |
|
| 2001 |
Tarran R, Grubb BR, Parsons D, Picher M, Hirsh AJ, Davis CW, Boucher RC. The CF salt controversy: in vivo observations and therapeutic approaches. Molecular Cell. 8: 149-58. PMID 11511368 DOI: 10.1016/S1097-2765(01)00286-6 |
0.338 |
|
| 2001 |
Tarran R, Grubb BR, Gatzy JT, Davis CW, Boucher RC. The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition. The Journal of General Physiology. 118: 223-36. PMID 11479349 DOI: 10.1085/Jgp.118.2.223 |
0.362 |
|
| 2001 |
Grubb BR, Pace AJ, Lee E, Koller BH, Boucher RC. Alterations in airway ion transport in NKCC1-deficient mice. American Journal of Physiology. Cell Physiology. 281: C615-23. PMID 11443061 DOI: 10.1152/Ajpcell.2001.281.2.C615 |
0.329 |
|
| 2001 |
Kreda SM, Gynn MC, Fenstermacher DA, Boucher RC, Gabriel SE. Expression and localization of epithelial aquaporins in the adult human lung American Journal of Respiratory Cell and Molecular Biology. 24: 224-234. PMID 11245621 DOI: 10.1165/Ajrcmb.24.3.4367 |
0.399 |
|
| 2001 |
Paradiso AM, Ribeiro CM, Boucher RC. Polarized signaling via purinoceptors in normal and cystic fibrosis airway epithelia. The Journal of General Physiology. 117: 53-67. PMID 11134231 DOI: 10.1085/Jgp.117.1.53 |
0.385 |
|
| 2001 |
Lazarowski ER, Boucher RC, Harden TK. Interplay of constitutively released nucleotides, nucleotide metabolism, and activity of P2Y receptors Drug Development Research. 53: 66-71. DOI: 10.1002/Ddr.1172 |
0.321 |
|
| 2001 |
Picher M, Boucher RC. Metabolism of extracellular nucleotides in human airways by a multienzyme system Drug Development Research. 52: 66-75. DOI: 10.1002/Ddr.1099 |
0.367 |
|
| 2000 |
Parsons DW, Hopkins PJ, Bourne AJ, Boucher RC, Martin AJ. Airway gene transfer in mouse nasal-airways: importance of identification of epithelial type for assessment of gene transfer. Gene Therapy. 7: 1810-5. PMID 11110412 DOI: 10.1038/Sj.Gt.3301317 |
0.382 |
|
| 2000 |
Coyne CB, Kelly MM, Boucher RC, Johnson LG. Enhanced epithelial gene transfer by modulation of tight junctions with sodium caprate. American Journal of Respiratory Cell and Molecular Biology. 23: 602-9. PMID 11062138 DOI: 10.1165/Ajrcmb.23.5.4164 |
0.676 |
|
| 2000 |
Grubb BR, Lee E, Pace AJ, Koller BH, Boucher RC. Intestinal ion transport in NKCC1-deficient mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G707-18. PMID 11005757 DOI: 10.1152/Ajpgi.2000.279.4.G707 |
0.353 |
|
| 2000 |
Homolya L, Steinberg TH, Boucher RC. Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia. The Journal of Cell Biology. 150: 1349-60. PMID 10995440 DOI: 10.1083/Jcb.150.6.1349 |
0.362 |
|
| 2000 |
Gabriel SE, Makhlina M, Martsen E, Thomas EJ, Lethem MI, Boucher RC. Permeabilization via the P2X7 purinoreceptor reveals the presence of a Ca2+ -activated Cl- conductance in the apical membrane of murine tracheal epithelial cells Journal of Biological Chemistry. 275: 35028-35033. PMID 10944530 DOI: 10.1074/Jbc.M004953200 |
0.406 |
|
| 2000 |
Noone PG, Hohneker KW, Zhou Z, Johnson LG, Foy C, Gipson C, Jones K, Noah TL, Leigh MW, Schwartzbach C, Efthimiou J, Pearlman R, Boucher RC, Knowles MR. Safety and biological efficacy of a lipid-CFTR complex for gene transfer in the nasal epithelium of adult patients with cystic fibrosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 105-14. PMID 10933918 DOI: 10.1006/Mthe.1999.0009 |
0.673 |
|
| 2000 |
Picher M, Boucher RC. Biochemical evidence for an ecto alkaline phosphodiesterase I in human airways. American Journal of Respiratory Cell and Molecular Biology. 23: 255-61. PMID 10919994 DOI: 10.1165/Ajrcmb.23.2.4088 |
0.366 |
|
| 2000 |
Lazarowski ER, Boucher RC, Harden TK. Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations. The Journal of Biological Chemistry. 275: 31061-8. PMID 10913128 DOI: 10.1074/Jbc.M003255200 |
0.311 |
|
| 2000 |
Rochelle LG, Li DC, Ye H, Lee E, Talbot CR, Boucher RC. Distribution of ion transport mRNAs throughout murine nose and lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L14-24. PMID 10893198 DOI: 10.1152/Ajplung.2000.279.1.L14 |
0.393 |
|
| 2000 |
Pickles RJ, Fahrner JA, Petrella JM, Boucher RC, Bergelson JM. Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer Journal of Virology. 74: 6050-6057. PMID 10846088 DOI: 10.1128/Jvi.74.13.6050-6057.2000 |
0.381 |
|
| 2000 |
Kreda SM, Pickles RJ, Lazarowski ER, Boucher RC. G-protein-coupled receptors as targets for gene transfer vectors using natural small-molecule ligands. Nature Biotechnology. 18: 635-40. PMID 10835601 DOI: 10.1038/76479 |
0.355 |
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| 2000 |
Johnson LG, Olsen JC, Naldini L, Boucher RC. Pseudotyped human lentiviral vector-mediated gene transfer to airway epithelia in vivo. Gene Therapy. 7: 568-74. PMID 10819571 DOI: 10.1038/Sj.Gt.3301138 |
0.657 |
|
| 2000 |
Matsui H, Davis CW, Tarran R, Boucher RC. Osmotic water permeabilities of cultured, well-differentiated normal and cystic fibrosis airway epithelia. The Journal of Clinical Investigation. 105: 1419-27. PMID 10811849 DOI: 10.1172/Jci4546 |
0.42 |
|
| 2000 |
Huang P, Trotter K, Boucher RC, Milgram SL, Stutts MJ. PKA holoenzyme is functionally coupled to CFTR by AKAPs. American Journal of Physiology. Cell Physiology. 278: C417-22. PMID 10666038 DOI: 10.1152/Ajpcell.2000.278.2.C417 |
0.358 |
|
| 2000 |
Donaldson SH, Lazarowski ER, Picher M, Knowles MR, Stutts MJ, Boucher RC. Basal Nucleotide Levels, Release, and Metabolism in Normal and Cystic Fibrosis Airways Molecular Medicine. 6: 969-982. DOI: 10.1007/Bf03401831 |
0.444 |
|
| 1999 |
Mohler PJ, Kreda SM, Boucher RC, Sudol M, Stutts MJ, Milgram SL. Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50. The Journal of Cell Biology. 147: 879-90. PMID 10562288 DOI: 10.1083/Jcb.147.4.879 |
0.353 |
|
| 1999 |
Cressman VL, Lazarowski E, Homolya L, Boucher RC, Koller BH, Grubb BR. Effect of loss of P2Y(2) receptor gene expression on nucleotide regulation of murine epithelial Cl(-) transport. The Journal of Biological Chemistry. 274: 26461-8. PMID 10473606 DOI: 10.1074/Jbc.274.37.26461 |
0.327 |
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| 1999 |
Homolya L, Watt WC, Lazarowski ER, Koller BH, Boucher RC. Nucleotide-regulated calcium signaling in lung fibroblasts and epithelial cells from normal and P2Y(2) receptor (-/-) mice. The Journal of Biological Chemistry. 274: 26454-60. PMID 10473605 DOI: 10.1074/Jbc.274.37.26454 |
0.362 |
|
| 1999 |
Kerem E, Bistritzer T, Hanukoglu A, Hofmann T, Zhou Z, Bennett W, MacLaughlin E, Barker P, Nash M, Quittell L, Boucher R, Knowles MR. Pulmonary epithelial sodium-channel dysfunction and excess airway liquid in pseudohypoaldosteronism. The New England Journal of Medicine. 341: 156-62. PMID 10403853 DOI: 10.1056/Nejm199907153410304 |
0.423 |
|
| 1999 |
Noone PG, Bennett WD, Regnis JA, Zeman KL, Carson JL, King M, Boucher RC, Knowles MR. Effect of aerosolized uridine-5'-triphosphate on airway clearance with cough in patients with primary ciliary dyskinesia. American Journal of Respiratory and Critical Care Medicine. 160: 144-9. PMID 10390392 DOI: 10.1164/Ajrccm.160.1.9806146 |
0.391 |
|
| 1999 |
Paradiso AM, Brown HA, Ye H, Harden TK, Boucher RC. Heterogeneous responses of cell Ca2+ in human airway epithelium. Experimental Lung Research. 25: 277-90. PMID 10378100 DOI: 10.1080/019021499270196 |
0.3 |
|
| 1999 |
Boucher RC. Molecular insights into the physiology of the 'thin film' of airway surface liquid. The Journal of Physiology. 631-8. PMID 10200413 DOI: 10.1111/J.1469-7793.1999.0631U.X |
0.386 |
|
| 1999 |
Talbot CL, Bosworth DG, Briley EL, Fenstermacher DA, Boucher RC, Gabriel SE, Barker PM. Quantitation and localization of ENaC subunit expression in fetal, newborn, and adult mouse lung. American Journal of Respiratory Cell and Molecular Biology. 20: 398-406. PMID 10030837 DOI: 10.1165/Ajrcmb.20.3.3283 |
0.387 |
|
| 1999 |
Boucher RC. Status of gene therapy for cystic fibrosis lung disease. The Journal of Clinical Investigation. 103: 441-5. PMID 10021450 DOI: 10.1172/Jci6330 |
0.489 |
|
| 1999 |
Noone PG, Bali D, Carson JL, Sannuti A, Gipson CL, Ostrowski LE, Bromberg PA, Boucher RC, Knowles MR. Discordant organ laterality in monozygotic twins with primary ciliary dyskinesia American Journal of Medical Genetics. 82: 155-160. PMID 9934981 DOI: 10.1002/(Sici)1096-8628(19990115)82:2<155::Aid-Ajmg11>3.0.Co;2-T |
0.311 |
|
| 1999 |
Grubb BR, Boucher RC. Pathophysiology of gene-targeted mouse models for cystic fibrosis. Physiological Reviews. 79: S193-214. PMID 9922382 DOI: 10.1152/Physrev.1999.79.1.S193 |
0.413 |
|
| 1999 |
Verghese MW, Boucher RC. Effects of ion composition and tonicity on human neutrophil antibacterial activity. American Journal of Respiratory Cell and Molecular Biology. 19: 920-8. PMID 9843926 DOI: 10.1165/Ajrcmb.19.6.3290 |
0.429 |
|
| 1998 |
Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, Davis CW, Boucher RC. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell. 95: 1005-15. PMID 9875854 DOI: 10.1016/S0092-8674(00)81724-9 |
0.484 |
|
| 1998 |
Parsons DW, Grubb BR, Johnson LG, Boucher RC. Enhanced in vivo airway gene transfer via transient modification of host barrier properties with a surface-active agent. Human Gene Therapy. 9: 2661-72. PMID 9874264 DOI: 10.1089/Hum.1998.9.18-2661 |
0.678 |
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| 1998 |
Barker PM, Nguyen MS, Gatzy JT, Grubb B, Norman H, Hummler E, Rossier B, Boucher RC, Koller B. Role of gammaENaC subunit in lung liquid clearance and electrolyte balance in newborn mice. Insights into perinatal adaptation and pseudohypoaldosteronism. The Journal of Clinical Investigation. 102: 1634-40. PMID 9788978 DOI: 10.1172/Jci3971 |
0.386 |
|
| 1998 |
Teramoto S, Bartlett JS, Mccarty D, Xiao X, Samulski RJ, Boucher RC. Factors influencing adeno-associated virus-mediated gene transfer to human cystic fibrosis airway epithelial cells: Comparison with adenovirus vectors Journal of Virology. 72: 8904-8912. PMID 9765435 DOI: 10.1128/Jvi.72.11.8904-8912.1998 |
0.421 |
|
| 1998 |
Johnson LG, Mewshaw JP, Ni H, Friedmann T, Boucher RC, Olsen JC. Effect of host modification and age on airway epithelial gene transfer mediated by a murine leukemia virus-derived vector. Journal of Virology. 72: 8861-72. PMID 9765431 DOI: 10.1128/Jvi.72.11.8861-8872.1998 |
0.701 |
|
| 1998 |
Matsui H, Randell SH, Peretti SW, Davis CW, Boucher RC. Coordinated clearance of periciliary liquid and mucus from airway surfaces. The Journal of Clinical Investigation. 102: 1125-31. PMID 9739046 DOI: 10.1172/Jci2687 |
0.373 |
|
| 1998 |
Grubb BR, Boucher RC. Effect of in vivo corticosteroids on Na+ transport across airway epithelia. The American Journal of Physiology. 275: C303-8. PMID 9688862 DOI: 10.1152/Ajpcell.1998.275.1.C303 |
0.379 |
|
| 1998 |
Short DB, Trotter KW, Reczek D, Kreda SM, Bretscher A, Boucher RC, Stutts MJ, Milgram SL. An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton. The Journal of Biological Chemistry. 273: 19797-801. PMID 9677412 DOI: 10.1074/Jbc.273.31.19797 |
0.391 |
|
| 1998 |
Hoganson DK, Matsui H, Batra RK, Boucher RC. Toxin gene-mediated growth inhibition of lung adenocarcinoma in an animal model of pleural malignancy. Human Gene Therapy. 9: 1143-56. PMID 9625253 DOI: 10.1089/Hum.1998.9.8-1143 |
0.362 |
|
| 1998 |
Pickles RJ, McCarty D, Matsui H, Hart PJ, Randell SH, Boucher RC. Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer Journal of Virology. 72: 6014-6023. PMID 9621064 DOI: 10.1128/Jvi.72.7.6014-6023.1998 |
0.462 |
|
| 1998 |
Hofmann T, Stutts MJ, Ziersch A, Ruckes C, Weber WM, Knowles MR, Lindemann H, Boucher RC. Effects of topically delivered benzamil and amiloride on nasal potential difference in cystic fibrosis American Journal of Respiratory and Critical Care Medicine. 157: 1844-1849. PMID 9620916 DOI: 10.1164/Ajrccm.157.6.9709043 |
0.316 |
|
| 1998 |
Watt WC, Lazarowski ER, Boucher RC. Cystic fibrosis transmembrane regulator-independent release of ATP. Its implications for the regulation of P2Y2 receptors in airway epithelia. The Journal of Biological Chemistry. 273: 14053-8. PMID 9593757 DOI: 10.1074/Jbc.273.22.14053 |
0.416 |
|
| 1998 |
Batra RK, Olsen JC, Pickles RJ, Hoganson DK, Boucher RC. Transduction of non-small cell lung cancer cells by adenoviral and retroviral vectors. American Journal of Respiratory Cell and Molecular Biology. 18: 402-10. PMID 9490658 DOI: 10.1165/Ajrcmb.18.3.2784 |
0.334 |
|
| 1998 |
Knowles MR, Noone PG, Hohneker K, Johnson LG, Boucher RC, Efthimiou J, Crawford C, Brown R, Schwartzbach C, Pearlman R. A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis. Human Gene Therapy. 9: 249-69. PMID 9472784 DOI: 10.1089/Hum.1998.9.2-249 |
0.615 |
|
| 1998 |
Hill WG, Harper GS, Rozaklis T, Boucher RC, Hopwood JJ. Organ-specific over-sulfation of glycosaminoglycans and altered extracellular matrix in a mouse model of cystic fibrosis. Biochemical and Molecular Medicine. 62: 113-22. PMID 9367807 DOI: 10.1006/Bmme.1997.2630 |
0.401 |
|
| 1998 |
Teramoto S, Bartlett JS, McCarty D, Xiao X, Samulski RJ, Boucher RC. Factors Influencing Adeno-Associated Virus-Mediated Gene Transfer to Human Cystic Fibrosis Airway Epithelial Cells: Comparison with Adenovirus Vectors Journal of Virology. 72: 8904-8912. DOI: 10.1128/jvi.72.11.8904-8912.1998 |
0.307 |
|
| 1997 |
Knowles MR, Robinson JM, Wood RE, Pue CA, Mentz WM, Wager GC, Gatzy JT, Boucher RC. Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects. The Journal of Clinical Investigation. 100: 2588-95. PMID 9366574 DOI: 10.1172/Jci119802 |
0.419 |
|
| 1997 |
Hummler E, Barker P, Talbot C, Wang Q, Verdumo C, Grubb B, Gatzy J, Burnier M, Horisberger JD, Beermann F, Boucher R, Rossier BC. A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism. Proceedings of the National Academy of Sciences of the United States of America. 94: 11710-5. PMID 9326675 DOI: 10.1073/Pnas.94.21.11710 |
0.34 |
|
| 1997 |
Lazarowski ER, Homolya L, Boucher RC, Harden TK. Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. The Journal of Biological Chemistry. 272: 24348-54. PMID 9305892 DOI: 10.1074/Jbc.272.39.24348 |
0.33 |
|
| 1997 |
Grubb BR, Schiretz FR, Boucher RC. Volume transport across tracheal and bronchial airway epithelia in a tubular culture system. The American Journal of Physiology. 273: C21-9. PMID 9252438 DOI: 10.1152/Ajpcell.1997.273.1.C21 |
0.386 |
|
| 1997 |
Lazarowski ER, Homolya L, Boucher RC, Harden TK. Identification of an ecto-nucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists. The Journal of Biological Chemistry. 272: 20402-7. PMID 9252347 DOI: 10.1074/Jbc.272.33.20402 |
0.345 |
|
| 1997 |
Hummler E, Barker P, Beermann F, Gatzy J, Verdumo C, Boucher R, Rossier BC. Role of the epithelial sodium channel in lung liquid clearance. Chest. 111: 113S. PMID 9184555 DOI: 10.1378/Chest.111.6_Supplement.113S |
0.317 |
|
| 1997 |
Stutts MJ, Rossier BC, Boucher RC. Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics. The Journal of Biological Chemistry. 272: 14037-40. PMID 9162024 DOI: 10.1074/Jbc.272.22.14037 |
0.352 |
|
| 1997 |
Lazarowski ER, Paradiso AM, Watt WC, Harden TK, Boucher RC. UDP activates a mucosal-restricted receptor on human nasal epithelial cells that is distinct from the P2Y2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 94: 2599-603. PMID 9122241 DOI: 10.1073/Pnas.94.6.2599 |
0.367 |
|
| 1997 |
Batra RK, Olsen JC, Hoganson DK, Caterson B, Boucher RC. Retroviral gene transfer is inhibited by chondroitin sulfate proteoglycans/glycosaminoglycans in malignant pleural effusions. The Journal of Biological Chemistry. 272: 11736-43. PMID 9115227 DOI: 10.1074/Jbc.272.18.11736 |
0.322 |
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| 1997 |
Highsmith WE, Burch LH, Zhou Z, Olsen JC, Strong TV, Smith T, Friedman KJ, Silverman LM, Boucher RC, Collins FS, Knowles MR. Identification of a splice site mutation (2789 +5 G > A) associated with small amounts of normal CFTR mRNA and mild cystic fibrosis. Human Mutation. 9: 332-8. PMID 9101293 DOI: 10.1002/(Sici)1098-1004(1997)9:4<332::Aid-Humu5>3.0.Co;2-7 |
0.694 |
|
| 1997 |
Piedimonte G, Pickles RJ, Lehmann JR, McCarty D, Costa DL, Boucher RC. Replication-deficient adenoviral vector for gene transfer potentiates airway neurogenic inflammation. American Journal of Respiratory Cell and Molecular Biology. 16: 250-8. PMID 9070609 DOI: 10.1165/Ajrcmb.16.3.9070609 |
0.381 |
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| 1997 |
Chinet TC, Gabriel SE, Penland CM, Sato M, Stutts MJ, Boucher RC, Van Scott MR. CFTR-like chloride channels in non-ciliated bronchiolar epithelial (Clara) cells. Biochemical and Biophysical Research Communications. 230: 470-5. PMID 9016805 DOI: 10.1006/Bbrc.1996.5939 |
0.342 |
|
| 1997 |
Matsui H, Johnson LG, Randell SH, Boucher RC. Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells. The Journal of Biological Chemistry. 272: 1117-26. PMID 8995411 DOI: 10.1074/Jbc.272.2.1117 |
0.658 |
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| 1997 |
Davenport SE, Mergey M, Cherqui G, Boucher RC, Gespach C, Gabriel SE. Deregulated expression and function of CFTR and Cl- secretion after activation of the Ras and Src/PyMT pathways in Caco-2 cells. Biochemical and Biophysical Research Communications. 229: 663-72. PMID 8954955 DOI: 10.1006/Bbrc.1996.1861 |
0.393 |
|
| 1996 |
Boucher RC. Current status of CF gene therapy. Trends in Genetics : Tig. 12: 81-4. PMID 8868343 DOI: 10.1016/0168-9525(96)81410-7 |
0.421 |
|
| 1996 |
Johnson LG, Pickles RJ, Boyles SE, Morris JC, Ye H, Zhou Z, Olsen JC, Boucher RC. In vitro assessment of variables affecting the efficiency and efficacy of adenovirus-mediated gene transfer to cystic fibrosis airway epithelia. Human Gene Therapy. 7: 51-9. PMID 8825868 DOI: 10.1089/Hum.1996.7.1-51 |
0.667 |
|
| 1996 |
Lazarowski ER, Watt WC, Stutts MJ, Brown HA, Boucher RC, Harden TK. Enzymatic synthesis of UTP gamma S, a potent hydrolysis resistant agonist of P2U-purinoceptors. British Journal of Pharmacology. 117: 203-9. PMID 8825364 DOI: 10.1111/J.1476-5381.1996.Tb15175.X |
0.332 |
|
| 1996 |
Larsen EH, Gabriei SE, Stutts MJ, Fullton J, Price EM, Boucher RC. Endogenous chloride channels of insect sf9 cells. Evidence for coordinated activity of small elementary channel units. The Journal of General Physiology. 107: 695-714. PMID 8783071 DOI: 10.1085/Jgp.107.6.695 |
0.305 |
|
| 1996 |
Pickles RJ, Barker PM, Ye H, Boucher RC. Efficient adenovirus-mediated gene transfer to basal but not columnar cells of cartilaginous airway epithelia. Human Gene Therapy. 7: 921-31. PMID 8727506 DOI: 10.1089/Hum.1996.7.8-921 |
0.433 |
|
| 1996 |
Olivier KN, Bennett WD, Hohneker KW, Zeman KL, Edwards LJ, Boucher RC, Knowles MR. Acute safety and effects on mucociliary clearance of aerosolized uridine 5'-triphosphate +/- amiloride in normal human adults. American Journal of Respiratory and Critical Care Medicine. 154: 217-23. PMID 8680683 DOI: 10.1164/Ajrccm.154.1.8680683 |
0.305 |
|
| 1996 |
Bennett WD, Olivier KN, Zeman KL, Hohneker KW, Boucher RC, Knowles MR. Effect of uridine 5'-triphosphate plus amiloride on mucociliary clearance in adult cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 153: 1796-801. PMID 8665037 DOI: 10.1164/Ajrccm.153.6.8665037 |
0.468 |
|
| 1996 |
Noah TL, Wortman IA, Hu PC, Leigh MW, Boucher RC. Cytokine production by cultured human bronchial epithelial cells infected with a replication-deficient adenoviral gene transfer vector or wild-type adenovirus type 5. American Journal of Respiratory Cell and Molecular Biology. 14: 417-24. PMID 8624246 DOI: 10.1165/Ajrcmb.14.5.8624246 |
0.366 |
|
| 1996 |
Hummler E, Barker P, Gatzy J, Beermann F, Verdumo C, Schmidt A, Boucher R, Rossier BC. Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice Nature Genetics. 12: 325-328. PMID 8589728 DOI: 10.1038/Ng0396-325 |
0.365 |
|
| 1995 |
Lazarowski ER, Watt WC, Stutts MJ, Boucher RC, Harden TK. Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate. British Journal of Pharmacology. 116: 1619-27. PMID 8564228 DOI: 10.1111/J.1476-5381.1995.Tb16382.X |
0.331 |
|
| 1995 |
Knowles MR, Olivier KN, Hohneker KW, Robinson J, Bennett WD, Boucher RC. Pharmacologic treatment of abnormal ion transport in the airway epithelium in cystic fibrosis. Chest. 107: 71S-76S. PMID 7842817 DOI: 10.1378/Chest.107.2_Supplement.71S |
0.481 |
|
| 1995 |
Leigh MW, Kylander JE, Yankaskas JR, Boucher RC. Cell proliferation in bronchial epithelium and submucosal glands of cystic fibrosis patients. American Journal of Respiratory Cell and Molecular Biology. 12: 605-12. PMID 7766425 DOI: 10.1165/Ajrcmb.12.6.7766425 |
0.475 |
|
| 1995 |
Burch LH, Talbot CR, Knowles MR, Canessa CM, Rossier BC, Boucher RC. Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways. The American Journal of Physiology. 269: C511-8. PMID 7653534 DOI: 10.1152/Ajpcell.1995.269.2.C511 |
0.731 |
|
| 1995 |
Geary CA, Davis CW, Paradiso AM, Boucher RC. Role of CNP in human airways: cGMP-mediated stimulation of ciliary beat frequency. The American Journal of Physiology. 268: L1021-8. PMID 7611424 DOI: 10.1152/Ajplung.1995.268.6.L1021 |
0.362 |
|
| 1995 |
Boucher RC, Gilbert IA, Hogg JC, King M, Knowles MR, Nadel J. Nonmuscular airway obstruction and asthma. American Journal of Respiratory and Critical Care Medicine. 152: 408-10. PMID 7599857 DOI: 10.1164/Ajrccm.152.1.7599857 |
0.312 |
|
| 1995 |
Teramoto S, Johnson LG, Huang W, Leigh MW, Boucher RC. Effect of adenoviral vector infection on cell proliferation in cultured primary human airway epithelial cells. Human Gene Therapy. 6: 1045-53. PMID 7578417 DOI: 10.1089/Hum.1995.6.8-1045 |
0.681 |
|
| 1995 |
Paradiso AM, Mason SJ, Lazarowski ER, Boucher RC. Membrane-restricted regulation of Ca2+ release and influx in polarized epithelia. Nature. 377: 643-6. PMID 7566178 DOI: 10.1038/377643A0 |
0.311 |
|
| 1995 |
Friedman KJ, Teichtahl H, De Kretser DM, Temple-Smith P, Southwick GJ, Silverman LM, Highsmith WE, Boucher RC, Knowles MR. Screening Young syndrome patients for CFTR mutations. American Journal of Respiratory and Critical Care Medicine. 152: 1353-7. PMID 7551394 DOI: 10.1164/Ajrccm.152.4.7551394 |
0.334 |
|
| 1995 |
Barker PM, Brigman KK, Paradiso AM, Boucher RC, Gatzy JT. Cl- secretion by trachea of CFTR (+/-) and (-/-) fetal mouse. American Journal of Respiratory Cell and Molecular Biology. 13: 307-13. PMID 7544595 DOI: 10.1165/Ajrcmb.13.3.7544595 |
0.37 |
|
| 1995 |
Stutts MJ, Canessa CM, Olsen JC, Hamrick M, Cohn JA, Rossier BC, Boucher RC. CFTR as a cAMP-dependent regulator of sodium channels. Science (New York, N.Y.). 269: 847-50. PMID 7543698 DOI: 10.1126/Science.7543698 |
0.331 |
|
| 1995 |
Knowles MR, Paradiso AM, Boucher RC. In vivo nasal potential difference: techniques and protocols for assessing efficacy of gene transfer in cystic fibrosis. Human Gene Therapy. 6: 445-55. PMID 7542031 DOI: 10.1089/Hum.1995.6.4-445 |
0.456 |
|
| 1995 |
Leung AY, Wong PY, Gabriel SE, Yankaskas JR, Boucher RC. cAMP- but not Ca(2+)-regulated Cl- conductance in the oviduct is defective in mouse model of cystic fibrosis. The American Journal of Physiology. 268: C708-12. PMID 7534985 DOI: 10.1152/ajpcell.1995.268.3.C708 |
0.341 |
|
| 1995 |
Johnson LG, Boyles SE, Wilson J, Boucher RC. Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells. The Journal of Clinical Investigation. 95: 1377-82. PMID 7533790 DOI: 10.1172/Jci117789 |
0.715 |
|
| 1995 |
Knowles MR, Olivier K, Noone P, Boucher RC. Pharmacologic modulation of salt and water in the airway epithelium in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 151: S65-9. PMID 7533608 DOI: 10.1164/Ajrccm/151.3_Pt_2.S65 |
0.481 |
|
| 1995 |
Barker PM, Boucher RC, Yankaskas JR. Bioelectric properties of cultured monolayers from epithelium of distal human fetal lung. The American Journal of Physiology. 268: L270-7. PMID 7532370 DOI: 10.1152/Ajplung.1995.268.2.L270 |
0.425 |
|
| 1995 |
Stutts MJ, Lazarowski ER, Paradiso AM, Boucher RC. Activation of CFTR Cl- conductance in polarized T84 cells by luminal extracellular ATP. The American Journal of Physiology. 268: C425-33. PMID 7532359 DOI: 10.1152/Ajpcell.1995.268.2.C425 |
0.369 |
|
| 1995 |
Boucher RC. The genetics of cystic fibrosis: a paradigm for uncovering new drug targets. Current Opinion in Biotechnology. 5: 639-42. PMID 7531034 DOI: 10.1016/0958-1669(94)90087-6 |
0.398 |
|
| 1995 |
Mohapatra NK, Cheng PW, Parker JC, Paradiso AM, Yankaskas JR, Boucher RC, Boat TF. Alteration of sulfation of glycoconjugates, but not sulfate transport and intracellular inorganic sulfate content in cystic fibrosis airway epithelial cells. Pediatric Research. 38: 42-8. PMID 7478795 DOI: 10.1203/00006450-199507000-00008 |
0.465 |
|
| 1994 |
Parr CE, Sullivan DM, Paradiso AM, Lazarowski ER, Burch LH, Olsen JC, Erb L, Weisman GA, Boucher RC, Turner JT. Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy. Proceedings of the National Academy of Sciences of the United States of America. 91: 3275-9. PMID 8159738 DOI: 10.1073/Pnas.91.8.3275 |
0.728 |
|
| 1994 |
Lazarowski ER, Boucher RC, Harden TK. Calcium-dependent release of arachidonic acid in response to purinergic receptor activation in airway epithelium. The American Journal of Physiology. 266: C406-15. PMID 8141254 DOI: 10.1152/Ajpcell.1994.266.2.C406 |
0.329 |
|
| 1994 |
Grubb BR, Paradiso AM, Boucher RC. Anomalies in ion transport in CF mouse tracheal epithelium. The American Journal of Physiology. 267: C293-300. PMID 8048488 DOI: 10.1152/Ajpcell.1994.267.1.C293 |
0.421 |
|
| 1994 |
Willumsen NJ, Davis CW, Boucher RC. Selective response of human airway epithelia to luminal but not serosal solution hypertonicity. Possible role for proximal airway epithelia as an osmolality transducer. The Journal of Clinical Investigation. 94: 779-87. PMID 8040333 DOI: 10.1172/Jci117397 |
0.368 |
|
| 1994 |
Parr CE, Sullivan DM, Paradiso AM, Lazarowski ER, Burch LH, Olsen JC, Erb L, Weisman GA, Boucher RC, Turner JT. Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy. Proceedings of the National Academy of Sciences of the United States of America. 91: 13067. PMID 7809171 DOI: 10.1073/Pnas.91.26.13067 |
0.693 |
|
| 1994 |
Stutts MJ, Fitz JG, Paradiso AM, Boucher RC. Multiple modes of regulation of airway epithelial chloride secretion by extracellular ATP. The American Journal of Physiology. 267: C1442-51. PMID 7526700 DOI: 10.1152/Ajpcell.1994.267.5.C1442 |
0.403 |
|
| 1994 |
Gabriel SE, Brigman KN, Koller BH, Boucher RC, Stutts MJ. Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model. Science (New York, N.Y.). 266: 107-9. PMID 7524148 DOI: 10.1126/Science.7524148 |
0.408 |
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| 1994 |
Grubb BR, Pickles RJ, Ye H, Yankaskas JR, Vick RN, Engelhardt JF, Wilson JM, Johnson LG, Boucher RC. Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans. Nature. 371: 802-6. PMID 7523956 DOI: 10.1038/371802A0 |
0.722 |
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| 1994 |
Boucher RC, Knowles MR, Johnson LG, Olsen JC, Pickles R, Wilson JM, Engelhardt J, Yang Y, Grossman M. Gene therapy for cystic fibrosis using E1-deleted adenovirus: a phase I trial in the nasal cavity. The University of North Carolina at Chapel Hill. Human Gene Therapy. 5: 615-39. PMID 7519885 DOI: 10.1089/Hum.1994.5.5-615 |
0.722 |
|
| 1994 |
Grubb BR, Vick RN, Boucher RC. Hyperabsorption of Na+ and raised Ca(2+)-mediated Cl- secretion in nasal epithelia of CF mice. The American Journal of Physiology. 266: C1478-83. PMID 7515571 DOI: 10.1152/Ajpcell.1994.266.5.C1478 |
0.413 |
|
| 1994 |
Chinet TC, Fullton JM, Yankaskas JR, Boucher RC, Stutts MJ. Mechanism of sodium hyperabsorption in cultured cystic fibrosis nasal epithelium: a patch-clamp study. The American Journal of Physiology. 266: C1061-8. PMID 7513953 DOI: 10.1152/Ajpcell.1994.266.4.C1061 |
0.367 |
|
| 1994 |
Clarke LL, Grubb BR, Yankaskas JR, Cotton CU, McKenzie A, Boucher RC. Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr(-/-) mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 479-83. PMID 7507247 DOI: 10.1073/Pnas.91.2.479 |
0.417 |
|
| 1994 |
Geary CA, Goy MF, Boucher RC. Synthesis and vectorial export of cGMP in airway epithelium: expression of soluble and CNP-specific guanylate cyclases. The American Journal of Physiology. 265: L598-605. PMID 7506495 DOI: 10.1152/Ajplung.1993.265.6.L598 |
0.348 |
|
| 1993 |
Mohapatra NK, Cheng PW, Parker JC, Paradiso AM, Yankaskas JR, Boucher RC, Boat TF. Sulfate concentrations and transport in human bronchial epithelial cells. The American Journal of Physiology. 264: C1231-7. PMID 8498482 DOI: 10.1152/Ajpcell.1993.264.5.C1231 |
0.357 |
|
| 1993 |
Bayle JY, Johnson LG, St George JA, Boucher RC, Olsen JC. High-efficiency gene transfer to primary monkey airway epithelial cells with retrovirus vectors using the gibbon ape leukemia virus receptor. Human Gene Therapy. 4: 161-70. PMID 8494925 DOI: 10.1089/Hum.1993.4.2-161 |
0.675 |
|
| 1993 |
Lethem MI, Dowell ML, Van Scott M, Yankaskas JR, Egan T, Boucher RC, Davis CW. Nucleotide regulation of goblet cells in human airway epithelial explants: normal exocytosis in cystic fibrosis. American Journal of Respiratory Cell and Molecular Biology. 9: 315-22. PMID 8398169 DOI: 10.1165/Ajrcmb/9.3.315 |
0.43 |
|
| 1993 |
Johnson LG, Dickman KG, Moore KL, Mandel LJ, Boucher RC. Enhanced Na+ transport in an air-liquid interface culture system. The American Journal of Physiology. 264: L560-5. PMID 8333549 DOI: 10.1152/Ajplung.1993.264.6.L560 |
0.644 |
|
| 1993 |
Yankaskas JR, Haizlip JE, Conrad M, Koval D, Lazarowski E, Paradiso AM, Rinehart CA, Sarkadi B, Schlegel R, Boucher RC. Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype. The American Journal of Physiology. 264: C1219-30. PMID 7684560 DOI: 10.1152/Ajpcell.1993.264.5.C1219 |
0.386 |
|
| 1993 |
Gabriel SE, Clarke LL, Boucher RC, Stutts MJ. CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship. Nature. 363: 263-8. PMID 7683773 DOI: 10.1038/363263A0 |
0.414 |
|
| 1993 |
Grubb B, Lazarowski E, Knowles M, Boucher R. Isobutylmethylxanthine fails to stimulate chloride secretion in cystic fibrosis airway epithelia American Journal of Respiratory Cell and Molecular Biology. 8: 454-460. PMID 7682824 DOI: 10.1165/Ajrcmb/8.4.454 |
0.427 |
|
| 1993 |
Olsen JC, Johnson LG, Wong-Sun ML, Moore KL, Swanstrom R, Boucher RC. Retrovirus-mediated gene transfer to cystic fibrosis airway epithelial cells: effect of selectable marker sequences on long-term expression. Nucleic Acids Research. 21: 663-9. PMID 7680124 DOI: 10.1093/Nar/21.3.663 |
0.653 |
|
| 1993 |
Clarke LL, Paradiso AM, Boucher RC. Histamine-induced Cl- secretion in human nasal epithelium: responses of apical and basolateral membranes. The American Journal of Physiology. 263: C1190-9. PMID 1335687 DOI: 10.1152/Ajpcell.1992.263.6.C1190 |
0.339 |
|
| 1992 |
Barker PM, Stiles AD, Boucher RC, Gatzy JT. Bioelectric properties of cultured epithelial monolayers from distal lung of 18-day fetal rat. The American Journal of Physiology. 262: L628-36. PMID 1590412 DOI: 10.1152/Ajplung.1992.262.5.L628 |
0.402 |
|
| 1992 |
Clarke LL, Paradiso AM, Mason SJ, Boucher RC. Effects of bradykinin on Na+ and Cl- transport in human nasal epithelium. The American Journal of Physiology. 262: C644-55. PMID 1550208 DOI: 10.1152/Ajpcell.1992.262.3.C644 |
0.351 |
|
| 1992 |
Knowles MR, Clarke LL, Boucher RC. Extracellular ATP and UTP induce chloride secretion in nasal epithelia of cystic fibrosis patients and normal subjects in vivo. Chest. 101: 60S-63S. PMID 1541209 DOI: 10.1378/Chest.101.3_Supplement.60S |
0.402 |
|
| 1992 |
Curiel DT, Agarwal S, Rømer MU, Wagner E, Cotten M, Birnstiel ML, Boucher RC. Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway. American Journal of Respiratory Cell and Molecular Biology. 6: 247-252. PMID 1540389 DOI: 10.1165/Ajrcmb/6.3.247 |
0.359 |
|
| 1992 |
Clarke LL, Boucher RC. Chloride secretory response to extracellular ATP in human normal and cystic fibrosis nasal epithelia. The American Journal of Physiology. 263: C348-56. PMID 1514583 DOI: 10.1152/Ajpcell.1992.263.2.C348 |
0.443 |
|
| 1992 |
Clarke LL, Burns KA, Bayle JY, Boucher RC, Van Scott MR. Sodium- and chloride-conductive pathways in cultured mouse tracheal epithelium. The American Journal of Physiology. 263: L519-25. PMID 1443155 DOI: 10.1152/Ajplung.1992.263.5.L519 |
0.416 |
|
| 1992 |
Gabriel SE, Price EM, Boucher RC, Stutts MJ. Small linear chloride channels are endogenous to nonepithelial cells. The American Journal of Physiology. 263: C708-13. PMID 1384347 DOI: 10.1152/Ajpcell.1992.263.3.C708 |
0.301 |
|
| 1992 |
Clarke LL, Grubb BR, Gabriel SE, Smithies O, Koller BH, Boucher RC. Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis. Science (New York, N.Y.). 257: 1125-8. PMID 1380724 DOI: 10.1126/Science.257.5073.1125 |
0.459 |
|
| 1992 |
Olsen JC, Johnson LG, Stutts MJ, Sarkadi B, Yankaskas JR, Swanstrom R, Boucher RC. Correction of the apical membrane chloride permeability defect in polarized cystic fibrosis airway epithelia following retroviral-mediated gene transfer. Human Gene Therapy. 3: 253-66. PMID 1379473 DOI: 10.1089/Hum.1992.3.3-253 |
0.734 |
|
| 1992 |
Stutts MJ, Chinet TC, Mason SJ, Fullton JM, Clarke LL, Boucher RC. Regulation of Cl- channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP. Proceedings of the National Academy of Sciences of the United States of America. 89: 1621-5. PMID 1371880 DOI: 10.1073/Pnas.89.5.1621 |
0.445 |
|
| 1992 |
Lazarowski ER, Mason SJ, Clarke L, Harden TK, Boucher RC. Adenosine receptors on human airway epithelia and their relationship to chloride secretion. British Journal of Pharmacology. 106: 774-82. PMID 1327386 DOI: 10.1111/J.1476-5381.1992.Tb14412.X |
0.428 |
|
| 1992 |
Engelhardt JF, Yankaskas JR, Ernst SA, Yang Y, Marino CR, Boucher RC, Cohn JA, Wilson JM. Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nature Genetics. 2: 240-8. PMID 1285365 DOI: 10.1038/Ng1192-240 |
0.42 |
|
| 1992 |
Johnson LG, Olsen JC, Sarkadi B, Moore KL, Swanstrom R, Boucher RC. Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis. Nature Genetics. 2: 21-5. PMID 1284642 DOI: 10.1038/Ng0992-21 |
0.715 |
|
| 1991 |
Yankaskas JR, Boucher RC. Transformation of airway epithelial cells with persistence of cystic fibrosis or normal ion transport phenotypes. Methods in Enzymology. 192: 565-71. PMID 1963667 DOI: 10.1016/0076-6879(90)92094-T |
0.379 |
|
| 1991 |
Knowles MR, Church NL, Waltner WE, Yankaskas JR, Gilligan P, King M, Edwards LJ, Helms RW, Boucher RC. Aerosolized amiloride as treatment of cystic fibrosis lung disease: a pilot study. Advances in Experimental Medicine and Biology. 290: 119-28; discussion 1. PMID 1950741 DOI: 10.1007/978-1-4684-5934-0_14 |
0.488 |
|
| 1991 |
Willumsen NJ, Boucher RC. Transcellular sodium transport in cultured cystic fibrosis human nasal epithelium. The American Journal of Physiology. 261: C332-41. PMID 1872375 DOI: 10.1152/Ajpcell.1991.261.2.C332 |
0.399 |
|
| 1991 |
Willumsen NJ, Boucher RC. Sodium transport and intracellular sodium activity in cultured human nasal epithelium. The American Journal of Physiology. 261: C319-31. PMID 1872374 DOI: 10.1152/Ajpcell.1991.261.2.C319 |
0.339 |
|
| 1991 |
Knowles MR, Clarke LL, Boucher RC. Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis. The New England Journal of Medicine. 325: 533-8. PMID 1857389 DOI: 10.1056/Nejm199108223250802 |
0.473 |
|
| 1991 |
Koller BH, Kim HS, Latour AM, Brigman K, Boucher RC, Scambler P, Wainwright B, Smithies O. Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10730-4. PMID 1720548 DOI: 10.1073/Pnas.88.23.10730 |
0.335 |
|
| 1991 |
Boucher RC, Chinet T, Willumsen N, Knowles MR, Stutts MJ. Ion transport in normal and CF airway epithelia. Advances in Experimental Medicine and Biology. 290: 105-15; discussion 1. PMID 1719753 DOI: 10.1007/978-1-4684-5934-0_13 |
0.461 |
|
| 1991 |
Mason SJ, Paradiso AM, Boucher RC. Regulation of transepithelial ion transport and intracellular calcium by extracellular ATP in human normal and cystic fibrosis airway epithelium. British Journal of Pharmacology. 103: 1649-56. PMID 1718521 DOI: 10.1111/J.1476-5381.1991.Tb09842.X |
0.411 |
|
| 1990 |
Gallo RL, Henkin J, Knowles MR, Church NL, Waltner WE, Yankaskas JR, Gilligan P, King M, Edwards LJ, Helms RW, Boucher RC. Aerosolized amiloride for the treatment of lung disease in cystic fibrosis (Reply) The New England Journal of Medicine. 323: 996-998. PMID 2402269 DOI: 10.1056/Nejm199010043231416 |
0.383 |
|
| 1990 |
Carson JL, Collier AM, Gambling TM, Knowles MR, Boucher RC. Ultrastructure of airway epithelial cell membranes among patients with cystic fibrosis. Human Pathology. 21: 640-7. PMID 2351392 DOI: 10.1016/S0046-8177(96)90011-8 |
0.433 |
|
| 1990 |
Haas M, Johnson LG, Boucher RC. Regulation of Na-K-Cl cotransport in cultured canine airway epithelia: a [3H]bumetanide binding study. The American Journal of Physiology. 259: C557-69. PMID 2221037 DOI: 10.1152/Ajpcell.1990.259.4.C557 |
0.641 |
|
| 1990 |
Knowles MR, Church NL, Waltner WE, Yankaskas JR, Gilligan P, King M, Edwards LJ, Helms RW, Boucher RC. A pilot study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis. The New England Journal of Medicine. 322: 1189-94. PMID 2157983 DOI: 10.1056/Nejm199004263221704 |
0.415 |
|
| 1989 |
Boucher RC, Cotton CU, Gatzy JT, Knowles MR, Yankaskas JR. Evidence for reduced Cl- and increased Na+ permeability in cystic fibrosis human primary cell cultures. The Journal of Physiology. 405: 77-103. PMID 3255805 DOI: 10.1113/Jphysiol.1988.Sp017322 |
0.423 |
|
| 1989 |
Cotton CU, Boucher RC, Gatzy JT. Paths of ion transport across canine fetal tracheal epithelium. Journal of Applied Physiology (Bethesda, Md. : 1985). 65: 2376-82. PMID 3215837 DOI: 10.1152/Jappl.1988.65.6.2376 |
0.367 |
|
| 1989 |
Cotton CU, Boucher RC, Gatzy JT. Bioelectric properties and ion transport across excised canine fetal and neonatal airways. Journal of Applied Physiology (Bethesda, Md. : 1985). 65: 2367-75. PMID 3215836 DOI: 10.1152/Jappl.1988.65.6.2367 |
0.39 |
|
| 1989 |
Henke D, Danilowicz RM, Curtis JF, Boucher RC, Eling TE. Metabolism of arachidonic acid by human nasal and bronchial epithelial cells. Archives of Biochemistry and Biophysics. 267: 426-36. PMID 3145716 DOI: 10.1016/0003-9861(88)90048-3 |
0.314 |
|
| 1989 |
Orlando RC, Powell DW, Croom RD, Berschneider HM, Boucher RC, Knowles MR. Colonic and esophageal transepithelial potential difference in cystic fibrosis. Gastroenterology. 96: 1041-8. PMID 2925051 DOI: 10.1016/0016-5085(89)91621-1 |
0.382 |
|
| 1989 |
Iannuzzi MC, Weber JL, Yankaskas J, Boucher R, Collins FS. The introduction of biologically active foreign genes into human respiratory epithelial cells using electroporation. The American Review of Respiratory Disease. 138: 965-8. PMID 2849346 DOI: 10.1164/Ajrccm/138.4.965 |
0.371 |
|
| 1989 |
Johnson LG, Cheng PW, Boucher RC. Albumin absorption by canine bronchial epithelium. Journal of Applied Physiology (Bethesda, Md. : 1985). 66: 2772-7. PMID 2745340 DOI: 10.1152/Jappl.1989.66.6.2772 |
0.641 |
|
| 1989 |
Cheng PW, Boat TF, Cranfill K, Yankaskas JR, Boucher RC. Increased sulfation of glycoconjugates by cultured nasal epithelial cells from patients with cystic fibrosis. The Journal of Clinical Investigation. 84: 68-72. PMID 2738159 DOI: 10.1172/Jci114171 |
0.47 |
|
| 1989 |
Willumsen NJ, Boucher RC. Shunt resistance and ion permeabilities in normal and cystic fibrosis airway epithelia. The American Journal of Physiology. 256: C1054-63. PMID 2719095 DOI: 10.1152/Ajpcell.1989.256.5.C1054 |
0.344 |
|
| 1989 |
Willumsen NJ, Davis CW, Boucher RC. Cellular Cl- transport in cultured cystic fibrosis airway epithelium. The American Journal of Physiology. 256: C1045-53. PMID 2719094 DOI: 10.1152/ajpcell.1989.256.5.C1045 |
0.315 |
|
| 1989 |
Willumsen NJ, Davis CW, Boucher RC. Intracellular Cl- activity and cellular Cl- pathways in cultured human airway epithelium. The American Journal of Physiology. 256: C1033-44. PMID 2719093 DOI: 10.1152/Ajpcell.1989.256.5.C1033 |
0.406 |
|
| 1989 |
Van Scott MR, Davis CW, Boucher RC. Na+ and Cl- transport across rabbit nonciliated bronchiolar epithelial (Clara) cells. The American Journal of Physiology. 256: C893-901. PMID 2705518 DOI: 10.1152/Ajpcell.1989.256.4.C893 |
0.35 |
|
| 1989 |
Boucher RC, Cheng EH, Paradiso AM, Stutts MJ, Knowles MR, Earp HS. Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms. The Journal of Clinical Investigation. 84: 1424-31. PMID 2478586 DOI: 10.1172/Jci114316 |
0.412 |
|
| 1989 |
Willumsen NJ, Boucher RC. Activation of an apical Cl- conductance by Ca2+ ionophores in cystic fibrosis airway epithelia. The American Journal of Physiology. 256: C226-33. PMID 2465689 DOI: 10.1152/Ajpcell.1989.256.2.C226 |
0.394 |
|
| 1988 |
Stutts MJ, Gatzy JT, Boucher RC. Activation of chloride conductance induced by potassium in tracheal epithelium. Pflugers Archiv : European Journal of Physiology. 411: 252-8. PMID 3380641 DOI: 10.1007/Bf00585111 |
0.306 |
|
| 1988 |
Stutts MJ, Gatzy JT, Boucher RC. Effects of metabolic inhibition on ion transport by dog bronchial epithelium. Journal of Applied Physiology (Bethesda, Md. : 1985). 64: 253-8. PMID 3356643 DOI: 10.1152/Jappl.1988.64.1.253 |
0.338 |
|
| 1988 |
Carson JL, Collier AM, Gambling TM, Leigh MW, Boucher RC, Hu SC, Boat TF. Development, organization, and function of tight junctional complexes in the tracheal epithelium of infant ferrets. The American Review of Respiratory Disease. 138: 666-74. PMID 3202419 DOI: 10.1164/Ajrccm/138.3.666 |
0.309 |
|
| 1988 |
Van Scott MR, Lee NP, Yankaskas JR, Boucher RC. Effect of hormones on growth and function of cultured canine tracheal epithelial cells. The American Journal of Physiology. 255: C237-45. PMID 3044136 DOI: 10.1152/Ajpcell.1988.255.2.C237 |
0.32 |
|
| 1988 |
Murphy E, Cheng E, Yankaskas J, Stutts MJ, Boucher RC. Cell calcium levels of normal and cystic fibrosis nasal epithelium. Pediatric Research. 24: 79-84. PMID 2842726 DOI: 10.1203/00006450-198807000-00019 |
0.426 |
|
| 1988 |
Willumsen N, Boucher R. Cl transport in normal (NL) and cystic fibrosis (CF) cultured human nasal epithelium (HNE) Comparative Biochemistry and Physiology Part a: Physiology. 90: 836. DOI: 10.1016/0300-9629(88)90806-7 |
0.433 |
|
| 1987 |
Boucher RC, James MK, Friedman M, Fullton J, Pimmel R, Gatzy JT. Acute cardiovascular and pulmonary effects of intravenous and aerosolized amiloride in the dog Toxicology and Applied Pharmacology. 87: 264-275. PMID 3824385 DOI: 10.1016/0041-008X(87)90288-2 |
0.426 |
|
| 1987 |
Cotton CU, Stutts MJ, Knowles MR, Gatzy JT, Boucher RC. Abnormal apical cell membrane in cystic fibrosis respiratory epithelium. An in vitro electrophysiologic analysis. The Journal of Clinical Investigation. 79: 80-5. PMID 3793933 DOI: 10.1172/Jci112812 |
0.426 |
|
| 1987 |
Van Scott MR, Hester S, Boucher RC. Ion transport by rabbit nonciliated bronchiolar epithelial cells (Clara cells) in culture. Proceedings of the National Academy of Sciences of the United States of America. 84: 5496-500. PMID 3474666 DOI: 10.1073/Pnas.84.15.5496 |
0.428 |
|
| 1987 |
Yankaskas JR, Gatzy JT, Boucher RC. Effects of raised osmolarity on canine tracheal epithelial ion transport function. Journal of Applied Physiology (Bethesda, Md. : 1985). 62: 2241-5. PMID 3112105 DOI: 10.1152/Jappl.1987.62.6.2241 |
0.363 |
|
| 1987 |
Stutts MJ, Knowles MR, Gatzy JT, Boucher RC. Oxygen consumption and ouabain binding sites in cystic fibrosis nasal epithelium. Pediatric Research. 20: 1316-20. PMID 2432456 DOI: 10.1203/00006450-198612000-00026 |
0.439 |
|
| 1987 |
Waltner WE, Boucher RC, Gatzy JT, Knowles MR. Pharmacotherapy of airway disease in cystic fibrosis Trends in Pharmacological Sciences. 8: 316-320. DOI: 10.1016/0165-6147(87)90127-1 |
0.461 |
|
| 1986 |
Yankaskas JR, Cotton CU, Knowles MR, Gatzy JT, Boucher RC. Culture of human nasal epithelial cells on collagen matrix supports. A comparison of bioelectric properties of normal and cystic fibrosis epithelia. The American Review of Respiratory Disease. 132: 1281-7. PMID 4073668 DOI: 10.1164/Arrd.1985.132.6.1281 |
0.352 |
|
| 1986 |
Gowen CW, Lawson EE, Gingras-Leatherman J, Gatzy JT, Boucher RC, Knowles MR. Increased nasal potential difference and amiloride sensitivity in neonates with cystic fibrosis. The Journal of Pediatrics. 108: 517-21. PMID 3958823 DOI: 10.1016/S0022-3476(86)80825-3 |
0.369 |
|
| 1986 |
Stutts MJ, Gatzy JT, Knowles MR, Cotton CU, Boucher RC. Effects of formaldehyde on bronchial ion transport. Toxicology and Applied Pharmacology. 82: 360-7. PMID 3945962 DOI: 10.1016/0041-008X(86)90213-9 |
0.343 |
|
| 1986 |
Boucher RC, Stutts MJ, Knowles MR, Cantley L, Gatzy JT. Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation. The Journal of Clinical Investigation. 78: 1245-52. PMID 3771796 DOI: 10.1172/Jci112708 |
0.428 |
|
| 1986 |
Van Scott MR, Yankaskas JR, Boucher RC. Culture of airway epithelial cells: research techniques. Experimental Lung Research. 11: 75-94. PMID 3530735 DOI: 10.3109/01902148609063272 |
0.321 |
|
| 1986 |
Stutts MJ, Schwab JH, Chen MG, Knowles MR, Boucher RC. Effects of Pseudomonas aeruginosa on bronchial epithelial ion transport. The American Review of Respiratory Disease. 134: 17-21. PMID 2425672 DOI: 10.1164/Arrd.1986.134.1.17 |
0.393 |
|
| 1985 |
Carson JL, Collier AM, Knowles MR, Boucher RC. Ultrastructural characterization of epithelial cell membranes in normal human conducting airway epithelium: A freeze-fracture study. The American Journal of Anatomy. 173: 257-68. PMID 20726125 DOI: 10.1002/Aja.1001730403 |
0.341 |
|
| 1985 |
Boucher RC, Ross DW, Knowles MR, Gatzy JT, Parker JC. Cl- permeabilities in red blood cells and peripheral blood lymphocytes from cystic fibrosis and control subjects. Pediatric Research. 18: 1336-9. PMID 6522149 DOI: 10.1203/00006450-198412000-00024 |
0.364 |
|
| 1985 |
Knowles MR, Gatzy JT, Boucher RC. Aldosterone metabolism and transepithelial potential difference in normal and cystic fibrosis subjects. Pediatric Research. 19: 676-9. PMID 4022674 DOI: 10.1203/00006450-198507000-00008 |
0.347 |
|
| 1985 |
Wu R, Yankaskas J, Cheng E, Knowles MR, Boucher R. Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis. The American Review of Respiratory Disease. 132: 311-20. PMID 3896079 DOI: 10.1164/Arrd.1985.132.2.311 |
0.315 |
|
| 1985 |
Stutts MJ, Cotton CU, Yankaskas JR, Cheng E, Knowles MR, Gatzy JT, Boucher RC. Chloride uptake into cultured airway epithelial cells from cystic fibrosis patients and normal individuals. Proceedings of the National Academy of Sciences of the United States of America. 82: 6677-81. PMID 3863120 DOI: 10.1073/Pnas.82.19.6677 |
0.459 |
|
| 1985 |
Yankaskas JR, Gatzy JT, Knowles MR, Boucher RC. Persistence Of Abnormal Chloride Ion Permeability In Cystic Fibrosis Nasal Epithelial Cells In Heterologous Culture The Lancet. 325: 954-956. PMID 2859414 DOI: 10.1016/S0140-6736(85)91728-3 |
0.428 |
|
| 1985 |
Gowen CW, Lawson EE, Gingras-Leatherman J, Boucher RC, Knowleg MR. 1767 INCREASED NASAL POTENTIAL DIFFERENCE AND AMILORIDE SENSITIVITY IN NEONATES WITH CYSTIC FIBROSIS Pediatric Research. 19: 405A-405A. DOI: 10.1203/00006450-198504000-01785 |
0.342 |
|
| 1984 |
Cotton CU, Lawson EE, Boucher RC, Gatzy JT. Bioelectric properties and ion transport of airways excised from adult and fetal sheep. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 55: 1542-9. PMID 6643190 DOI: 10.1152/Jappl.1983.55.5.1542 |
0.337 |
|
| 1983 |
Jarnigan F, Davis JD, Bromberg PA, Gatzy JT, Boucher RC. Bioelectric properties and ion transport of excised rabbit trachea. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 55: 1884-92. PMID 6319342 DOI: 10.1152/Jappl.1983.55.6.1884 |
0.306 |
|
| 1983 |
Boucher RC, Knowles MR, Stutts MJ, Gatzy JT. Epithelial dysfunction in cystic fibrosis lung disease Lung. 161: 1-17. DOI: 10.1007/Bf02713837 |
0.445 |
|
| 1982 |
Boucher RC, Stutts MJ, Gatzy JT. Regional differences in bioelectric properties and ion flow in excised canine airways. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 51: 706-14. PMID 7327972 DOI: 10.1152/Jappl.1981.51.3.706 |
0.337 |
|
| 1982 |
Knowles M, Gatzy J, Boucher R. Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis. The New England Journal of Medicine. 305: 1489-95. PMID 7300874 DOI: 10.1056/Nejm198112173052502 |
0.448 |
|
| 1982 |
Ally AI, Boucher RC, Knowles MR, Eling TE. Metabolism of prostaglandin endoperoxide by microsomes from human lung parenchyma and comparison with metabolites produced by pig, bovine, rat, mouse and guinea-pig. Prostaglandins. 24: 575-584. PMID 6758042 DOI: 10.1016/0090-6980(82)90015-6 |
0.316 |
|
| 1981 |
Stutts MJ, Boucher RC, Bromberg PA, Gatzy JT. Effects of ammonium and nitrate salts on lon transport across the excised canine trachea. Toxicology and Applied Pharmacology. 60: 91-105. PMID 7281180 DOI: 10.1016/0041-008X(81)90139-3 |
0.319 |
|
| 1981 |
Carson JL, Collier AM, Knowles MR, Boucher RC, Rose JG. Morphometric aspects of ciliary distribution and ciliogenesis in human nasal epithelium. Proceedings of the National Academy of Sciences of the United States of America. 78: 6996-9. PMID 6947271 DOI: 10.1073/Pnas.78.11.6996 |
0.335 |
|
| 1981 |
Stempel DA, Boucher RC. Respiratory infection and airway reactivity. The Medical Clinics of North America. 65: 1045-53. PMID 6270475 DOI: 10.1016/S0025-7125(16)31488-2 |
0.325 |
|
| 1979 |
Paré PD, Michoud MC, Boucher RC, Hogg JC. Pulmonary effects of acute and chronic antigen exposure of immunized guinea pigs. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 46: 346-53. PMID 422452 DOI: 10.1152/Jappl.1979.46.2.346 |
0.345 |
|
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