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Chao-Kai Chou, Ph.D. - Publications

Affiliations: 
2009 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Oncology, Molecular Biology, Biomedical Engineering
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yang R, Sun L, Li CF, Wang YH, Yao J, Li H, Yan M, Chang WC, Hsu JM, Cha JH, Hsu JL, Chou CW, Sun X, Deng Y, Chou CK, et al. Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy. Nature Communications. 12: 832. PMID 33547304 DOI: 10.1038/s41467-021-21099-2  0.589
2020 Chou CK, Liu YL, Chen YI, Huang PJ, Tsou PH, Chen CT, Lee HH, Wang YN, Hsu JL, Lee JF, Yankeelov TE, Kameoka J, Yeh HC, Hung MC. Digital Receptor Occupancy Assay in Quantifying On- and Off-Target Binding Affinities of Therapeutic Antibodies. Acs Sensors. PMID 32073836 DOI: 10.1021/Acssensors.9B01736  0.434
2019 Lee HH, Wang YN, Xia W, Chen CH, Rau KM, Ye L, Wei Y, Chou CK, Wang SC, Yan M, Tu CY, Hsia TC, Chiang SF, Chao KSC, Wistuba II, et al. Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy. Cancer Cell. PMID 31327656 DOI: 10.1016/j.ccell.2019.06.008  0.319
2019 Liu YL, Chou CK, Kim M, Vasisht R, Kuo YA, Ang P, Liu C, Perillo EP, Chen YA, Blocher K, Horng H, Chen YI, Nguyen DT, Yankeelov TE, Hung MC, et al. Assessing metastatic potential of breast cancer cells based on EGFR dynamics. Scientific Reports. 9: 3395. PMID 30833579 DOI: 10.1038/S41598-018-37625-0  0.439
2018 Chou CK, Huang PJ, Tsou PH, Wei Y, Lee HH, Wang YN, Liu YL, Shi C, Yeh HC, Kameoka J, Hung MC. A flow-proteometric platform for analyzing protein concentration (FAP): Proof of concept for quantification of PD-L1 protein in cells and tissues. Biosensors & Bioelectronics. 117: 97-103. PMID 29890396 DOI: 10.1016/J.Bios.2018.05.053  0.405
2018 Wang YN, Lee HH, Chou CK, Yang WH, Wei Y, Chen CT, Yao J, Hsu JL, Zhu C, Ying H, Ye Y, Wang WJ, Lim SO, Xia W, Ko HW, et al. Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer. Cancer Cell. PMID 29606349 DOI: 10.1016/J.Ccell.2018.02.012  0.411
2018 Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, et al. Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1. Cancer Cell. 33: 187-201.e10. PMID 29438695 DOI: 10.1016/J.Ccell.2018.01.009  0.397
2018 Liu Y, Chou C, Kim M, Vasisht R, Liu C, Perillo EP, Horng H, Hung M, Dunn AK, Yeh T. Effect of Epithelial-Mesenchymal Transition on EGFR Dynamics Revealed by Single-Particle Tracking Biophysical Journal. 114: 534a. DOI: 10.1016/J.Bpj.2017.11.2920  0.414
2017 Korphaisarn K, Chou CK, Xia WY, Clarke CN, Katkhuda R, Davis JS, Raghav KP, Liao HW, Wu JY, Menter DG, Maru DM, Hung MC, Kopetz S. Arginine methylation of EGFR: a new biomarker for predicting resistance to anti-EGFR treatment. American Journal of Cancer Research. 7: 2587-2599. PMID 29312811  0.421
2017 Huang PJ, Chou CK, Chen CT, Yamaguchi H, Qu J, Muliana A, Hung MC, Kameoka J. Pneumatically Actuated Soft Micromold Device for Fabricating Collagen and Matrigel Microparticles. Soft Robotics. 4: 390-399. PMID 29251562 DOI: 10.1089/Soro.2016.0073  0.389
2017 Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Molecular Cell. 67: 733-743.e4. PMID 28844863 DOI: 10.1016/J.Molcel.2017.07.026  0.421
2017 Jiao S, Xia W, Yamaguchi H, Wei Y, Chen MK, Hsu JM, Hsu JL, Yu WH, Du Y, Lee HH, Li CW, Chou CK, Lim SO, Chang SS, Litton JK, et al. PARP inhibitor upregulates PD-L1 expression and enhances cancer-associated immunosuppression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28167507 DOI: 10.1158/1078-0432.CCR-16-3215  0.359
2017 Korphaisarn K, Chou C, Xia W, Clarke C, Davis JS, Liao H, Crosby S, Manuel S, Wu J, Menter D, Hung M, Kopetz S. Arginine methylation of EGFR in circulating tumor cells: A new biomarker for predicting resistance to anti-EGFR agents. Journal of Clinical Oncology. 35: 3590-3590. DOI: 10.1200/Jco.2017.35.15_Suppl.3590  0.494
2016 Liu YL, Perillo EP, Liu C, Yu P, Chou CK, Hung MC, Dunn AK, Yeh HC. Segmentation of 3D Trajectories Acquired by TSUNAMI Microscope: An Application to EGFR Trafficking. Biophysical Journal. 111: 2214-2227. PMID 27851944 DOI: 10.1016/J.Bpj.2016.09.041  0.34
2016 Wang Y, Hsu JM, Kang Y, Wei Y, Lee PC, Chang SJ, Hsu YH, Hsu JL, Wang HL, Chang WC, Li CW, Liao HW, Chang SS, Xia W, Ko HW, ... Chou CK, et al. Oncogenic functions of Gli in pancreatic adenocarcinoma are supported by its PRMT1-mediated methylation. Cancer Research. PMID 27758883 DOI: 10.1158/0008-5472.CAN-16-0715  0.468
2016 Chou CK, Tsou PH, Hsu JL, Lee HH, Wang YN, Kameoka J, Hung MC. Analysis of Individual Signaling Complexes by mMAPS, a Flow-Proteometric System. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 114: 20.11.1-20.11.22. PMID 27038387 DOI: 10.1002/0471142727.Mb2011S114  0.418
2016 Chou CK, Fan CC, Lin PS, Liao PY, Tung JC, Hsieh CH, Hung MC, Chen CH, Chang WC. Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis. Oncotarget. PMID 27013588 DOI: 10.18632/oncotarget.8264  0.474
2016 Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, ... ... Chou CK, et al. AKT1 inhibits epithelial-to-mesenchymal transition in breast cancer through phosphorylation-dependent Twist1 degradation. Cancer Research. PMID 26759241 DOI: 10.1158/0008-5472.CAN-15-1941  0.778
2016 Liu Y, Perillo EP, Liu C, Yu PM, Chou C, Hung M, Dunn AK, Yeh T. Dynamics of EGFR Trafficking from Membrane into Deep Cytoplasm Revealed by a Spatiotemporally Multiplexed 3D Tracking Microscope Biophysical Journal. 110: 638a. DOI: 10.1016/J.Bpj.2015.11.3416  0.423
2015 Liao HW, Hsu JM, Xia W, Wang HL, Wang YN, Chang WC, Arold ST, Chou CK, Tsou PH, Yamaguchi H, Fang YF, Lee HJ, Lee HH, Tai SK, Yang MH, et al. PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response. The Journal of Clinical Investigation. PMID 26571401 DOI: 10.1172/Jci82826  0.451
2015 Perillo EP, Liu YL, Huynh K, Liu C, Chou CK, Hung MC, Yeh HC, Dunn AK. Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination. Nature Communications. 6: 7874. PMID 26219252 DOI: 10.1038/Ncomms8874  0.353
2015 Chou C, Lee H, Tsou P, Chen C, Hsu J, Yamaguchi H, Wang Y, Hsu JL, Lee J, Kameoka J, Hung M. Abstract 5120: Using flow-proteometric platform to analyze individual signaling complexes in tumor tissue Cancer Research. 75: 5120-5120. DOI: 10.1158/1538-7445.Am2015-5120  0.532
2014 Chou CK, Lee HH, Tsou PH, Chen CT, Hsu JM, Yamaguchi H, Wang YN, Lee HJ, Hsu JL, Lee JF, Kameoka J, Hung MC. mMAPS: a flow-proteometric technique to analyze protein-protein interactions in individual signaling complexes. Science Signaling. 7: rs1. PMID 24595109 DOI: 10.1126/Scisignal.2004620  0.458
2014 Zhang K, Chou CK, Xia X, Hung MC, Qin L. Block-Cell-Printing for live single-cell printing. Proceedings of the National Academy of Sciences of the United States of America. 111: 2948-53. PMID 24516129 DOI: 10.1073/Pnas.1313661111  0.385
2013 Saldana SM, Lee HH, Lowery FJ, Khotskaya YB, Xia W, Zhang C, Chang SS, Chou CK, Steeg PS, Yu D, Hung MC. Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis. Plos One. 8: e73406. PMID 24039934 DOI: 10.1371/Journal.Pone.0073406  0.609
2013 Chou C, Lee H, Tsou P, Yamaguchi H, Wang Y, Lee H, Kameoka J, Hung M. Abstract 5169: Flow-proteometric analysis of single signaling complex. Cancer Research. 73: 5169-5169. DOI: 10.1158/1538-7445.Am2013-5169  0.532
2012 Hong S, Tsou PH, Chou CK, Yamaguchi H, Su CB, Hung MC, Kameoka J. Microfluidic three-dimensional hydrodynamic flow focusing for the rapid protein concentration analysis. Biomicrofluidics. 6: 24132. PMID 23785388 DOI: 10.1063/1.4730332  0.325
2012 Liu M, Lee DF, Chen CT, Yen CJ, Li LY, Lee HJ, Chang CJ, Chang WC, Hsu JM, Kuo HP, Xia W, Wei Y, Chiu PC, Chou CK, Du Y, et al. IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression. Molecular Cell. 45: 171-84. PMID 22196886 DOI: 10.1016/J.Molcel.2011.11.018  0.803
2011 Chen YJ, Huang WC, Wei YL, Hsu SC, Yuan P, Lin HY, Wistuba II, Lee JJ, Yen CJ, Su WC, Chang KY, Chang WC, Chou TC, Chou CK, Tsai CH, et al. Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells. Plos One. 6: e21428. PMID 21731744 DOI: 10.1371/Journal.Pone.0021428  0.502
2011 Hsu JM, Chen CT, Chou CK, Kuo HP, Li LY, Lin CY, Lee HJ, Wang YN, Liu M, Liao HW, Shi B, Lai CC, Bedford MT, Tsai CH, Hung MC. Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nature Cell Biology. 13: 174-81. PMID 21258366 DOI: 10.1038/Ncb2158  0.732
2010 Hong S, Wang YN, Yamaguchi H, Sreenivasappa H, Chou CK, Tsou PH, Hung MC, Kameoka J. MEASUREMENT of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS). Journal of Biomaterials and Nanobiotechnology. 1: 31-36. PMID 21804949 DOI: 10.4236/Jbnb.2010.11004  0.443
2010 Cheng X, Xia W, Yang JY, Hsu JL, Chou CK, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of p21(CIP1/WAF1) in mammary epithelium accelerates mammary tumorigenesis and promotes lung metastasis. Biochemical and Biophysical Research Communications. 403: 103-7. PMID 21040707 DOI: 10.1016/J.Bbrc.2010.10.126  0.767
2010 Chou CK, Jing N, Yamaguchi H, Tsou PH, Lee HH, Chen CT, Wang YN, Hong S, Su C, Kameoka J, Hung MC. Rapid detection of two-protein interaction with a single fluorophore by using a microfluidic device. The Analyst. 135: 2907-12. PMID 20877860 DOI: 10.1039/C0An00229A  0.366
2010 Cheng X, Xia W, Yang JY, Hsu JL, Lang JY, Chou CK, Du Y, Sun HL, Wyszomierski SL, Mills GB, Muller WJ, Yu D, Hung MC. Activation of murine double minute 2 by Akt in mammary epithelium delays mammary involution and accelerates mammary tumorigenesis. Cancer Research. 70: 7684-9. PMID 20841468 DOI: 10.1158/0008-5472.Can-09-3231  0.785
2010 Yamaguchi H, Chen CT, Chou CK, Pal A, Bornmann W, Hortobagyi GN, Hung MC. Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation Oncogene. 29: 5619-5629. PMID 20676141 DOI: 10.1038/Onc.2010.295  0.493
2010 Chou CK, Jing N, Yamaguchi H, Tsou PH, Lee HH, Chen CT, Wang YN, Hong S, Su C, Kameoka J, Hung MC. High speed digital protein interaction analysis using microfluidic single molecule detection system. Lab On a Chip. 10: 1793-8. PMID 20498894 DOI: 10.1039/C002937H  0.408
2010 Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Science Signaling. 3: ra9. PMID 20145209 DOI: 10.1126/Scisignal.2000590  0.763
2010 Chou C, Jing N, Yamaguchi H, Tsou P, Kameoka J, Hung M. Abstract 4017: Identifying Protein-Protein Interactions in Single Protein Complex level by Microchannel Device Cancer Research. 70: 4017-4017. DOI: 10.1158/1538-7445.Am10-4017  0.507
2010 Hong S, Sreenivasappa H, Yamaguchi H, Wang Y, Chou C, Hung M, Kameoka J. Raster Image Correlation Spectroscopy for Anti-Cancer Drug Screening Based on the Identification of Molecular Dynamics Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.2185  0.498
2009 Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Chen CT, Huo L, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, et al. KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Molecular Cell. 36: 131-40. PMID 19818716 DOI: 10.1016/J.Molcel.2009.07.025  0.784
2009 Chou CK, Lee DF, Sun HL, Li LY, Lin CY, Huang WC, Hsu JM, Kuo HP, Yamaguchi H, Wang YN, Liu M, Wu HY, Liao PC, Yen CJ, Hung MC. The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription. Molecular Carcinogenesis. 48: 1048-58. PMID 19526459 DOI: 10.1002/Mc.20557  0.773
2008 Tsou PH, Chou CK, Saldana S, Hung MC, Kameoka J. The fabrication and testing of electrospun silica nanofiber membranes for the detection of proteins. Nanotechnology. 19: 445714. PMID 19081800 DOI: 10.1088/0957-4484/19/44/445714  0.387
2008 Lee DF, Kuo HP, Chen CT, Wei Y, Chou CK, Hung JY, Yen CJ, Hung MC. IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance. International Journal of Molecular Medicine. 22: 633-8. PMID 18949383 DOI: 10.3892/ijmm_00000065  0.757
2008 Yen CJ, Izzo JG, Lee DF, Guha S, Wei Y, Wu TT, Chen CT, Kuo HP, Hsu JM, Sun HL, Chou CK, Buttar NS, Wang KK, Huang P, Ajani J, et al. Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. Cancer Research. 68: 2632-40. PMID 18413730 DOI: 10.1158/0008-5472.Can-07-5460  0.775
2007 Lee DF, Kuo HP, Chen CT, Hsu JM, Chou CK, Wei Y, Sun HL, Li LY, Ping B, Huang WC, He X, Hung JY, Lai CC, Ding Q, Su JL, et al. IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway. Cell. 130: 440-55. PMID 17693255 DOI: 10.1016/j.cell.2007.05.058  0.768
2007 Chen CH, Lu PJ, Chen YC, Fu SL, Wu KJ, Tsou AP, Lee YC, Lin TC, Hsu SL, Lin WJ, Huang CY, Chou CK. FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway. Oncogene. 26: 4272-83. PMID 17237822 DOI: 10.1038/sj.onc.1210207  0.359
2006 Chou CK, Hung JY, Liu JC, Chen CT, Hung MC. An attenuated Salmonella oral DNA vaccine prevents the growth of hepatocellular carcinoma and colon cancer that express alpha-fetoprotein. Cancer Gene Therapy. 13: 746-52. PMID 16410824 DOI: 10.1038/Sj.Cgt.7700927  0.399
2006 Ou-Yang F, Lan KL, Chen CT, Liu JC, Weng CL, Chou CK, Xie X, Hung JY, Wei Y, Hortobagyi GN, Hung MC. Endostatin-cytosine deaminase fusion protein suppresses tumor growth by targeting neovascular endothelial cells. Cancer Research. 66: 378-84. PMID 16397252 DOI: 10.1158/0008-5472.CAN-05-1578  0.506
2005 Yu CT, Hsu JM, Lee YC, Tsou AP, Chou CK, Huang CY. Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A. Molecular and Cellular Biology. 25: 5789-800. PMID 15987997 DOI: 10.1128/MCB.25.14.5789-5800.2005  0.315
2003 Liu WK, Chien CY, Chou CK, Su JY. An LKB1-interacting protein negatively regulates TNFalpha-induced NF-kappaB activation. Journal of Biomedical Science. 10: 242-52. PMID 12595760 DOI: 10.1007/BF02256059  0.348
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