Michael J. Grusby - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Immunology, Molecular Biology, Cell Biology

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, et al. ZBTB20 is required for anterior pituitary development and lactotrope specification. Nature Communications. 7: 11121. PMID 27079169 DOI: 10.1038/Ncomms11121  0.382
2014 Lajoie S, Lewkowich I, Herman NS, Sproles A, Pesce JT, Wynn TA, Grusby MJ, Hamid Q, Wills-Karp M. IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses Clinical and Experimental Allergy. 44: 976-985. PMID 24807637 DOI: 10.1111/Cea.12341  0.549
2013 Sutherland AP, Joller N, Michaud M, Liu SM, Kuchroo VK, Grusby MJ. IL-21 promotes CD8+ CTL activity via the transcription factor T-bet. Journal of Immunology (Baltimore, Md. : 1950). 190: 3977-84. PMID 23479229 DOI: 10.4049/Jimmunol.1201730  0.558
2012 Qu Z, Fu J, Ma H, Zhou J, Jin M, Mapara MY, Grusby MJ, Xiao G. PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease. Cell & Bioscience. 2: 23. PMID 22731402 DOI: 10.1186/2045-3701-2-23  0.378
2012 Zhang Y, Xie Z, Zhou L, Li L, Zhang H, Zhou G, Ma X, Herrera PL, Liu Z, Grusby MJ, Zhang WJ. The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice. Gastroenterology. 142: 1571-1580.e6. PMID 22374165 DOI: 10.1053/J.Gastro.2012.02.043  0.347
2011 Tanaka T, Yamamoto Y, Muromoto R, Ikeda O, Sekine Y, Grusby MJ, Kaisho T, Matsuda T. PDLIM2 inhibits T helper 17 cell development and granulomatous inflammation through degradation of STAT3. Science Signaling. 4: ra85. PMID 22155789 DOI: 10.1126/Scisignal.2001637  0.508
2010 Qu Z, Yan P, Fu J, Jiang J, Grusby MJ, Smithgall TE, Xiao G. DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target. Cancer Research. 70: 1766-72. PMID 20145149 DOI: 10.1158/0008-5472.Can-09-3263  0.336
2010 Fathman JW, Gurish MF, Hemmers S, Bonham K, Friend DS, Grusby MJ, Glimcher LH, Mowen KA. NIP45 controls the magnitude of the type 2 T helper cell response. Proceedings of the National Academy of Sciences of the United States of America. 107: 3663-8. PMID 20133688 DOI: 10.1073/Pnas.0914700107  0.563
2010 Hiramatsu Y, Suto A, Kashiwakuma D, Kanari H, Kagami S, Ikeda K, Hirose K, Watanabe N, Grusby MJ, Iwamoto I, Nakajima H. c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-beta inhibits c-Maf-induced IL-21 production in CD4+ T cells. Journal of Leukocyte Biology. 87: 703-12. PMID 20042469 DOI: 10.1189/Jlb.0909639  0.523
2009 Sutherland AP, Zhang H, Zhang Y, Michaud M, Xie Z, Patti ME, Grusby MJ, Zhang WJ. Zinc finger protein Zbtb20 is essential for postnatal survival and glucose homeostasis. Molecular and Cellular Biology. 29: 2804-15. PMID 19273596 DOI: 10.1128/Mcb.01667-08  0.333
2009 Zullo AJ, Michaud M, Zhang W, Grusby MJ. Identification of the small protein rich in arginine and glycine (SRAG): a newly identified nucleolar protein that can regulate cell proliferation. The Journal of Biological Chemistry. 284: 12504-11. PMID 19254951 DOI: 10.1074/Jbc.M809436200  0.338
2009 Sutherland AP, Van Belle T, Wurster AL, Suto A, Michaud M, Zhang D, Grusby MJ, von Herrath M. Interleukin-21 is required for the development of type 1 diabetes in NOD mice. Diabetes. 58: 1144-55. PMID 19208913 DOI: 10.2337/Db08-0882  0.355
2009 Yan P, Fu J, Qu Z, Li S, Tanaka T, Grusby MJ, Xiao G. PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation. Blood. 113: 4370-80. PMID 19131544 DOI: 10.1182/Blood-2008-10-185660  0.38
2009 Jin H, Oyoshi MK, Le Y, Bianchi T, Koduru S, Mathias CB, Kumar L, Le Bras S, Young D, Collins M, Grusby MJ, Wenzel J, Bieber T, Boes M, Silberstein LE, et al. IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. The Journal of Clinical Investigation. 119: 47-60. PMID 19075398 DOI: 10.1172/Jci32310  0.449
2008 Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ. Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver Proceedings of the National Academy of Sciences of the United States of America. 105: 10859-10864. PMID 18669658 DOI: 10.1073/Pnas.0800647105  0.309
2008 Suto A, Kashiwakuma D, Kagami S, Hirose K, Watanabe N, Yokote K, Saito Y, Nakayama T, Grusby MJ, Iwamoto I, Nakajima H. Development and characterization of IL-21-producing CD4+ T cells. The Journal of Experimental Medicine. 205: 1369-79. PMID 18474630 DOI: 10.1084/Jem.20072057  0.529
2008 Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA. IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung. Journal of Immunology (Baltimore, Md. : 1950). 180: 522-9. PMID 18097054 DOI: 10.4049/Jimmunol.180.1.522  0.494
2008 LAJOIE S, HERMAN N, DIENGER K, SPROLES A, PESCE J, WYNN T, GRUSBY M, WILLSKARP M. IL-21 Receptor Signaling Partially Mediates Th2-mediated Allergic Airway Responses Journal of Allergy and Clinical Immunology. 121: S145-S145. DOI: 10.1016/j.jaci.2007.12.1115  0.371
2007 Becskei A, Grusby MJ. Contribution of IL-12R mediated feedback loop to Th1 cell differentiation. Febs Letters. 581: 5199-206. PMID 17950290 DOI: 10.1016/J.Febslet.2007.10.007  0.546
2007 Touma M, Antonini V, Kumar M, Osborn SL, Bobenchik AM, Keskin DB, Connolly JE, Grusby MJ, Reinherz EL, Clayton LK. Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption. Journal of Immunology (Baltimore, Md. : 1950). 179: 1681-92. PMID 17641034 DOI: 10.4049/Jimmunol.179.3.1681  0.569
2007 Tanaka T, Grusby MJ, Kaisho T. PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit. Nature Immunology. 8: 584-91. PMID 17468759 DOI: 10.1038/Ni1464  0.314
2007 Nakahira M, Tanaka T, Robson BE, Mizgerd JP, Grusby MJ. Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL. Immunity. 26: 163-76. PMID 17306571 DOI: 10.1016/J.Immuni.2007.01.010  0.484
2007 Gao C, Guo H, Mi Z, Grusby MJ, Kuo PC. Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages. Journal of Immunology (Baltimore, Md. : 1950). 178: 1870-81. PMID 17237438 DOI: 10.4049/Jimmunol.178.3.1870  0.381
2007 Keane MP, Gomperts BN, Weigt S, Xue YY, Burdick MD, Nakamura H, Zisman DA, Ardehali A, Saggar R, Lynch JP, Hogaboam C, Kunkel SL, Lukacs NW, Ross DJ, Grusby MJ, et al. IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome. Journal of Immunology (Baltimore, Md. : 1950). 178: 511-9. PMID 17182591 DOI: 10.4049/Jimmunol.178.1.511  0.498
2007 Jin H, Mathias C, Young D, Collins M, Grusby M, Oettgen H, Geha R. An Essential Role For Il-21R In The Immune Response To Epicutaneous Sensitization In A Mouse Model Of Atopic Dermatitis Journal of Allergy and Clinical Immunology. 119: 523-524. DOI: 10.1016/J.Jaci.2006.12.628  0.429
2006 Suto A, Wurster AL, Reiner SL, Grusby MJ. IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression. Journal of Immunology (Baltimore, Md. : 1950). 177: 3721-7. PMID 16951332 DOI: 10.4049/Jimmunol.177.6.3721  0.548
2006 Pesce J, Kaviratne M, Ramalingam TR, Thompson RW, Urban JF, Cheever AW, Young DA, Collins M, Grusby MJ, Wynn TA. The IL-21 receptor augments Th2 effector function and alternative macrophage activation. The Journal of Clinical Investigation. 116: 2044-55. PMID 16778988 DOI: 10.1172/Jci27727  0.502
2006 Huang H, Kearney JF, Grusby MJ, Benoist C, Mathis D. Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen. Proceedings of the National Academy of Sciences of the United States of America. 103: 3734-9. PMID 16505356 DOI: 10.1073/Pnas.0600214103  0.37
2006 Panoskaltsis-Mortari A, Price A, Tram K, McFadden R, Ehrhardt MJ, Grusby MJ, Blazar BR. Amelioration of Idiopathic Pneumonia Syndrome (IPS) and GVHD by KGF-Pretreatment Is Partly Mediated Via a STAT-6-Dependent Pathway in the Host. Blood. 108: 3189-3189. DOI: 10.1182/Blood.V108.11.3189.3189  0.406
2005 Tanaka T, Soriano MA, Grusby MJ. SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling. Immunity. 22: 729-36. PMID 15963787 DOI: 10.1016/J.Immuni.2005.04.008  0.686
2005 Mehta DS, Wurster AL, Weinmann AS, Grusby MJ. NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 2016-21. PMID 15684054 DOI: 10.1073/Pnas.0409512102  0.785
2004 Mehta DS, Wurster AL, Grusby MJ. Biology of IL-21 and the IL-21 receptor. Immunological Reviews. 202: 84-95. PMID 15546387 DOI: 10.1111/J.0105-2896.2004.00201.X  0.768
2004 Liu Q, Arseculeratne C, Liu Z, Whitmire J, Grusby MJ, Finkelman FD, Darling TN, Cheever AW, Swearengen J, Urban JF, Gause WC. Simultaneous deficiency in CD28 and STAT6 results in chronic ectoparasite-induced inflammatory skin disease. Infection and Immunity. 72: 3706-15. PMID 15213110 DOI: 10.1128/Iai.72.7.3706-3715.2004  0.507
2004 Chitnis T, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo. Journal of Immunology (Baltimore, Md. : 1950). 172: 4260-5. PMID 15034039 DOI: 10.4049/Jimmunol.172.7.4260  0.436
2004 Satake Y, Diaz BL, Balestrieri B, Lam BK, Kanaoka Y, Grusby MJ, Arm JP. Role of group V phospholipase A2 in zymosan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption. The Journal of Biological Chemistry. 279: 16488-94. PMID 14761945 DOI: 10.1074/Jbc.M313748200  0.331
2004 Mentink-Kane MM, Cheever AW, Thompson RW, Hari DM, Kabatereine NB, Vennervald BJ, Ouma JH, Mwatha JK, Jones FM, Donaldson DD, Grusby MJ, Dunne DW, Wynn TA. IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis. Proceedings of the National Academy of Sciences of the United States of America. 101: 586-90. PMID 14699044 DOI: 10.1073/Pnas.0305064101  0.462
2003 Ma HL, Whitters MJ, Konz RF, Senices M, Young DA, Grusby MJ, Collins M, Dunussi-Joannopoulos K. IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 171: 608-15. PMID 12847225 DOI: 10.4049/Jimmunol.171.2.608  0.54
2003 Mehta DS, Wurster AL, Whitters MJ, Young DA, Collins M, Grusby MJ. IL-21 induces the apoptosis of resting and activated primary B cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4111-8. PMID 12682241 DOI: 10.4049/Jimmunol.170.8.4111  0.768
2003 Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, Taniguchi M, Grusby MJ, DeKruyff RH, Umetsu DT. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nature Medicine. 9: 582-8. PMID 12669034 DOI: 10.1038/Nm851  0.515
2003 Wood N, Whitters MJ, Jacobson BA, Witek J, Sypek JP, Kasaian M, Eppihimer MJ, Unger M, Tanaka T, Goldman SJ, Collins M, Donaldson DD, Grusby MJ. Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2. The Journal of Experimental Medicine. 197: 703-9. PMID 12642602 DOI: 10.1084/Jem.20020906  0.515
2003 Chiaramonte MG, Mentink-Kane M, Jacobson BA, Cheever AW, Whitters MJ, Goad ME, Wong A, Collins M, Donaldson DD, Grusby MJ, Wynn TA. Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response. The Journal of Experimental Medicine. 197: 687-701. PMID 12642601 DOI: 10.1084/Jem.20020903  0.543
2003 Bream JH, Curiel RE, Yu CR, Egwuagu CE, Grusby MJ, Aune TM, Young HA. IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells. Blood. 102: 207-14. PMID 12637316 DOI: 10.1182/Blood-2002-08-2602  0.544
2003 Chung DR, Kasper DL, Panzo RJ, Chitnis T, Grusby MJ, Sayegh MH, Tzianabos AO, Chtinis T. CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 170: 1958-63. PMID 12574364 DOI: 10.4049/Jimmunol.170.4.1958  0.503
2002 Wurster AL, Rodgers VL, Satoskar AR, Whitters MJ, Young DA, Collins M, Grusby MJ. Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells. The Journal of Experimental Medicine. 196: 969-77. PMID 12370258 DOI: 10.1084/Jem.20020620  0.539
2002 Eyles JL, Metcalf D, Grusby MJ, Hilton DJ, Starr R. Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1. The Journal of Biological Chemistry. 277: 43735-40. PMID 12221108 DOI: 10.1074/Jbc.M208586200  0.538
2002 Finnegan A, Grusby MJ, Kaplan CD, O'Neill SK, Eibel H, Koreny T, Czipri M, Mikecz K, Zhang J. IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 169: 3345-52. PMID 12218156 DOI: 10.4049/Jimmunol.169.6.3345  0.535
2002 Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ. Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. The Journal of Biological Chemistry. 277: 27169-75. PMID 12023955 DOI: 10.1074/Jbc.M201207200  0.541
2002 Kasaian MT, Whitters MJ, Carter LL, Lowe LD, Jussif JM, Deng B, Johnson KA, Witek JS, Senices M, Konz RF, Wurster AL, Donaldson DD, Collins M, Young DA, Grusby MJ. IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Immunity. 16: 559-69. PMID 11970879 DOI: 10.1016/S1074-7613(02)00295-9  0.556
2002 Wurster AL, Withers DJ, Uchida T, White MF, Grusby MJ. Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis. Molecular and Cellular Biology. 22: 117-26. PMID 11739727 DOI: 10.1128/Mcb.22.1.117-126.2002  0.588
2001 Lim YC, Xie H, Come CE, Alexander SI, Grusby MJ, Lichtman AH, Luscinskas FW. IL-12, STAT4-dependent up-regulation of CD4(+) T cell core 2 beta-1,6-n-acetylglucosaminyltransferase, an enzyme essential for biosynthesis of P-selectin ligands. Journal of Immunology (Baltimore, Md. : 1950). 167: 4476-84. PMID 11591774 DOI: 10.4049/Jimmunol.167.8.4476  0.511
2001 Chitnis T, Najafian N, Benou C, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. 108: 739-47. PMID 11544280 DOI: 10.1172/Jci12563  0.511
2001 Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, Gravallese EM, Friend D, Grusby MJ, Alt F, Glimcher LH. Plasma cell differentiation requires the transcription factor XBP-1. Nature. 412: 300-7. PMID 11460154 DOI: 10.1038/35085509  0.358
2001 Daheshia M, Friend DS, Grusby MJ, Austen KF, Katz HR. Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice. The Journal of Experimental Medicine. 194: 227-34. PMID 11457897 DOI: 10.1084/Jem.194.2.227  0.391
2001 Zhou P, Szot G, Guo Z, Kim O, He G, Wang J, Grusby M, Newell K, Thistlethwaite J, Bluestone J, Alegre M. Role of STAT6 signaling in the induction and long-term maintenance of tolerance mediated by CTLA4-Ig. Transplantation Proceedings. 33: 214-6. PMID 11266784 DOI: 10.1016/S0041-1345(00)01979-5  0.313
2001 Exley MA, Bigley NJ, Cheng O, Tahir SMA, Smiley ST, Carter QL, Stills HF, Grusby MJ, Koezuka Y, Taniguchi M, Balk SP. CD1d-reactive T-cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus Journal of Leukocyte Biology. 69: 713-718. DOI: 10.1189/Jlb.69.5.713  0.416
2000 Lawless VA, Zhang S, Ozes ON, Bruns HA, Oldham I, Hoey T, Grusby MJ, Kaplan MH. Stat4 regulates multiple components of IFN-gamma-inducing signaling pathways. Journal of Immunology (Baltimore, Md. : 1950). 165: 6803-8. PMID 11120802 DOI: 10.4049/Jimmunol.165.12.6803  0.56
2000 Ostrand-Rosenberg S, Grusby MJ, Clements VK. Cutting edge: Stat6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma Journal of Immunology. 165: 6015-6019. PMID 11086031 DOI: 10.4049/Jimmunol.165.11.6015  0.42
2000 Zhou P, Szot GL, Guo Z, Kim O, He G, Wang J, Grusby MJ, Newell KA, Thistlethwaite JR, Bluestone JA, Alegre ML. Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. Journal of Immunology (Baltimore, Md. : 1950). 165: 5580-7. PMID 11067913 DOI: 10.4049/Jimmunol.165.10.5580  0.428
2000 Tarleton RL, Grusby MJ, Zhang L. Increased susceptibility of Stat4-deficient and enhanced resistance in Stat6-deficient mice to infection with Trypanosoma cruzi. Journal of Immunology (Baltimore, Md. : 1950). 165: 1520-5. PMID 10903759 DOI: 10.4049/Jimmunol.165.3.1520  0.416
2000 Kishimoto K, Dong VM, Issazadeh S, Fedoseyeva EV, Waaga AM, Yamada A, Sho M, Benichou G, Auchincloss H, Grusby MJ, Khoury SJ, Sayegh MH. The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo. The Journal of Clinical Investigation. 106: 63-72. PMID 10880049 DOI: 10.1172/Jci9586  0.427
2000 Wurster AL, Tanaka T, Grusby MJ. The biology of Stat4 and Stat6. Oncogene. 19: 2577-84. PMID 10851056 DOI: 10.1038/Sj.Onc.1203485  0.566
2000 Nikolic B, Lee S, Bronson RT, Grusby MJ, Sykes M. Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets Journal of Clinical Investigation. 105: 1289-1298. PMID 10792004 DOI: 10.1172/Jci7894  0.49
2000 Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, Grusby MJ, Glimcher LH. An essential role in liver development for transcription factor XBP-1. Genes & Development. 14: 152-7. PMID 10652269 DOI: 10.1101/Gad.14.2.152  0.327
2000 Shimamura M, Huang YY, Suda Y, Kusumoto S, Sato K, Grusby MJ, Sato H, Nakayama T, Taniguchi M. Positive selection of NKT cells by CD1(+), CD11c(+) non-lymphoid cells residing in the extrathymic organs. European Journal of Immunology. 29: 3962-70. PMID 10602005 DOI: 10.1002/(Sici)1521-4141(199912)29:12<3962::Aid-Immu3962>3.0.Co;2-1  0.342
2000 Dong VM, Kishimoto K, Exeni A, Yamada A, Waaga AM, Briscoe DM, Auchincloss H, Grusby MJ, Khoury SJ, Sayegh MH. THE DIFFERENTIAL ROLE OF CD28-B7 VERSUS CD40L-CD40 IN REGULATING ALLOIMMUNE RESPONSES IN STAT 4 VERSUS STAT 6 GENE KNOCKOUT MICE. Transplantation. 69: S379. DOI: 10.1097/00007890-200004271-01027  0.375
1999 Kriebel P, Patel BKR, Nelson SA, Grusby MJ, LaRochelle WJ. Consequences of Stat6 deletion on Sis/PDGF- and IL-4-induced proliferation and transcriptional activation in murine fibroblasts Oncogene. 18: 7294-7302. PMID 10602484 DOI: 10.1038/Sj.Onc.1203148  0.547
1999 Homann D, Holz A, Bot A, Coon B, Wolfe T, Petersen J, Dyrberg TP, Grusby MJ, von Herrath MG. Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway. Immunity. 11: 463-72. PMID 10549628 DOI: 10.1016/S1074-7613(00)80121-1  0.521
1999 Ong CJ, Ip S, Teh SJ, Wong C, Jirik FR, Grusby MJ, Teh HS. A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice Cellular Immunology. 196: 60-68. PMID 10486156 DOI: 10.1006/Cimm.1999.1537  0.482
1999 Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines Immunity. 10: 745-751. PMID 10403649 DOI: 10.1016/S1074-7613(00)80073-4  0.549
1999 Morse HC, McCarty T, Giese NA, Taddesse-Heath L, Grusby MJ. STAT6-deficient mice exhibit normal induction of murine AIDS and expression of immunoglobulin E following infection with LP-BM5 murine leukemia viruses. Journal of Virology. 73: 7093-5. PMID 10400816 DOI: 10.1128/Jvi.73.8.7093-7095.1999  0.538
1999 Behar SM, Dascher CC, Grusby MJ, Wang CR, Brenner MB. Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis. The Journal of Experimental Medicine. 189: 1973-80. PMID 10377193 DOI: 10.1084/Jem.189.12.1973  0.397
1999 Kim JI, Li T, Ho IC, Grusby MJ, Glimcher LH. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development Proceedings of the National Academy of Sciences of the United States of America. 96: 3781-3785. PMID 10097114 DOI: 10.1073/Pnas.96.7.3781  0.332
1999 Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ. Marking IL-4-producing cells by knock-in of the IL-4 gene. International Immunology. 11: 243-7. PMID 10069422 DOI: 10.1093/Intimm/11.2.243  0.561
1999 Hoey T, Grusby MJ. STATs as mediators of cytokine-induced responses. Advances in Immunology. 71: 145-62. PMID 9917912 DOI: 10.1016/S0065-2776(08)60401-0  0.307
1998 Lowe ME, Kaplan MH, Jackson-Grusby L, D'Agostino D, Grusby MJ. Decreased neonatal dietary fat absorption and T cell cytotoxicity in pancreatic lipase-related protein 2-deficient mice. The Journal of Biological Chemistry. 273: 31215-21. PMID 9813028 DOI: 10.1074/Jbc.273.47.31215  0.384
1998 Oukka M, Ho IC, de la Brousse FC, Hoey T, Grusby MJ, Glimcher LH. The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity. 9: 295-304. PMID 9768749 DOI: 10.1016/S1074-7613(00)80612-3  0.468
1998 Kaplan MH, Wurster AL, Grusby MJ. A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells. The Journal of Experimental Medicine. 188: 1191-6. PMID 9743537 DOI: 10.1084/Jem.188.6.1191  0.562
1998 Kaplan MH, Grusby MJ. Regulation of T helper cell differentiation by STAT molecules. Journal of Leukocyte Biology. 64: 2-5. PMID 9665267 DOI: 10.1002/Jlb.64.1.2  0.538
1998 Kaplan MH, Daniel C, Schindler U, Grusby MJ. Stat proteins control lymphocyte proliferation by regulating p27Kip1 expression. Molecular and Cellular Biology. 18: 1996-2003. PMID 9528771 DOI: 10.1128/Mcb.18.4.1996  0.578
1998 Ranger AM, Grusby MJ, Hodge MR, Gravallese EM, de la Brousse FC, Hoey T, Mickanin C, Baldwin HS, Glimcher LH. The transcription factor NF-ATc is essential for cardiac valve formation. Nature. 392: 186-90. PMID 9515964 DOI: 10.1038/32426  0.35
1998 Kuperman D, Schofield B, Wills-Karp M, Grusby MJ. Signal transducer and activator of transcription factor 6 (Stat6)- deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production Journal of Experimental Medicine. 187: 939-948. PMID 9500796 DOI: 10.1084/Jem.187.6.939  0.53
1998 Ranger AM, Hodge MR, Gravallese EM, Oukka M, Davidson L, Alt FW, de la Brousse FC, Hoey T, Grusby M, Glimcher LH. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity. 8: 125-34. PMID 9462518 DOI: 10.1016/S1074-7613(00)80465-3  0.525
1997 Croy BA, Ashkar AA, Foster RA, DiSanto JP, Magram J, Carson D, Gendler SJ, Grusby MJ, Wagner N, Muller W, Guimond MJ. Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy. Journal of Reproductive Immunology. 35: 111-33. PMID 9421796 DOI: 10.1016/S0165-0378(97)00054-5  0.458
1997 Smiley ST, Stitt TN, Grusby MJ. Cross-linking of protein S bound to lymphocytes promotes aggregation and inhibits proliferation. Cellular Immunology. 181: 120-6. PMID 9398399 DOI: 10.1006/Cimm.1997.1210  0.445
1997 Smiley ST, Boyer SN, Heeb MJ, Griffin JH, Grusby MJ. Protein S is inducible by interleukin 4 in T cells and inhibits lymphoid cell procoagulant activity. Proceedings of the National Academy of Sciences of the United States of America. 94: 11484-9. PMID 9326636 DOI: 10.1073/Pnas.94.21.11484  0.513
1997 Smiley ST, Grusby MJ. Dual-receptor T cells expressing one self-restricted TCR. Scandinavian Journal of Immunology. 45: 726-30. PMID 9201314 DOI: 10.1046/J.1365-3083.1997.D01-445.X  0.39
1997 Grusby MJ. Stat4- and Stat6-deficient mice as models for manipulating T helper cell responses. Biochemical Society Transactions. 25: 359-60. PMID 9191117 DOI: 10.1042/Bst0250359  0.44
1997 Lee RS, Grusby MJ, Laufer TM, Colvin R, Glimcher LH, Auchincloss H. CD8+ effector cells responding to residual class I antigens, with help from CD4+ cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts. Transplantation. 63: 1123-33. PMID 9133474 DOI: 10.1097/00007890-199704270-00012  0.337
1997 Smiley ST, Kaplan MH, Grusby MJ. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells. Science (New York, N.Y.). 275: 977-9. PMID 9020080 DOI: 10.1126/Science.275.5302.977  0.513
1996 Kaplan MH, Boyer SN, Grusby MJ. Genomic organization of the murine CTL lipase gene. Genomics. 35: 606-9. PMID 8812501 DOI: 10.1006/Geno.1996.0407  0.413
1996 Kaplan MH, Sun YL, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature. 382: 174-7. PMID 8700209 DOI: 10.1038/382174A0  0.603
1996 Tarleton RL, Grusby MJ, Postan M, Glimcher LH. Trypanosoma cruzi infection in MHC-deficient mice: Further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease International Immunology. 8: 13-22. PMID 8671585 DOI: 10.1093/Intimm/8.1.13  0.362
1996 Steele DJ, Laufer TM, Smiley ST, Ando Y, Grusby MJ, Glimcher LH, Auchincloss H. Two levels of help for B cell alloantibody production. The Journal of Experimental Medicine. 183: 699-703. PMID 8627185 DOI: 10.1084/Jem.183.2.699  0.364
1996 Kaplan MH, Schindler U, Smiley ST, Grusby MJ. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity. 4: 313-9. PMID 8624821 DOI: 10.1016/S1074-7613(00)80439-2  0.443
1996 Hodge MR, Ranger AM, Charles de la Brousse F, Hoey T, Grusby MJ, Glimcher LH. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity. 4: 397-405. PMID 8612134 DOI: 10.1016/S1074-7613(00)80253-8  0.573
1996 Smiley ST, Rudensky AY, Glimcher LH, Grusby MJ. Truncation of the class II beta-chain cytoplasmic domain influences the level of class II/invariant chain-derived peptide complexes. Proceedings of the National Academy of Sciences of the United States of America. 93: 241-4. PMID 8552613 DOI: 10.1073/Pnas.93.1.241  0.305
1996 Reimold AM, Grusby MJ, Kosaras B, Fries JW, Mori R, Maniwa S, Clauss IM, Collins T, Sidman RL, Glimcher MJ, Glimcher LH. Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature. 379: 262-5. PMID 8538792 DOI: 10.1038/379262A0  0.355
1995 Linette GP, Grusby MJ, Hedrick SM, Hansen TH, Glimcher LH, Korsmeyer SJ. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity. 1: 197-205. PMID 7889408 DOI: 10.1016/1074-7613(94)90098-1  0.338
1995 Chakkalath HR, Theodos CM, Markowitz JS, Grusby MJ, Glimcher LH, Titus RG. Class II major histocompatibility complex-deficient mice initially control an infection with leishmania major but succumb to the disease Journal of Infectious Diseases. 171: 1302-1308. PMID 7751707 DOI: 10.1093/Infdis/171.5.1302  0.345
1995 Grusby MJ, Glimcher LH. Immune responses in MHC class II-deficient mice Annual Review of Immunology. 13: 417-435. PMID 7612230 DOI: 10.1146/Annurev.Iy.13.040195.002221  0.353
1995 Smiley ST, Laufer TM, Lo D, Glimcher LH, Grusby MJ. Transgenic mice expressing MHC class II molecules with truncated A beta cytoplasmic domains reveal signaling-independent defects in antigen presentation. International Immunology. 7: 665-77. PMID 7547694 DOI: 10.1093/Intimm/7.4.665  0.407
1994 Lee RS, Grusby MJ, Glimcher LH, Winn HJ, Auchincloss H. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo Journal of Experimental Medicine. 179: 865-872. PMID 8113680 DOI: 10.1084/Jem.179.3.865  0.37
1994 Matsushima GK, Taniike M, Glimcher LH, Grusby MJ, Frelinger JA, Suzuki K, Ting JP. Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy. Cell. 78: 645-56. PMID 8069913 DOI: 10.1016/0092-8674(94)90529-0  0.377
1994 Mombaerts P, Mizoguchi E, Ljunggren HG, Iacomini J, Ishikawa H, Wang L, Grusby MJ, Glimcher LH, Winn HJ, Bhan AK. Peripheral lymphoid development and function in TCR mutant mice. International Immunology. 6: 1061-70. PMID 7947457 DOI: 10.1093/Intimm/6.7.1061  0.361
1994 Takahama Y, Suzuki H, Katz KS, Grusby MJ, Singer A. Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC. Nature. 371: 67-70. PMID 7915400 DOI: 10.1038/371067A0  0.367
1994 Jevnikar AM, Grusby MJ, Glimcher LH. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-1pr mice Journal of Experimental Medicine. 179: 1137-1143. PMID 7908320 DOI: 10.1084/Jem.179.4.1137  0.37
1993 Todd MD, Grusby MJ, Lederer JA, Lacy E, Lichtman AH, Glimcher LH. Transcription of the interleukin 4 gene is regulated by multiple promoter elements. The Journal of Experimental Medicine. 177: 1663-74. PMID 8496684 DOI: 10.1084/Jem.177.6.1663  0.532
1993 Cantor H, Crump AL, Raman VK, Liu H, Markowitz JS, Grusby MJ, Glimcher LH. Immunoregulatory effects of superantigens: interactions of staphylococcal enterotoxins with host MHC and non-MHC products. Immunological Reviews. 131: 27-42. PMID 8486393 DOI: 10.1111/J.1600-065X.1993.Tb01528.X  0.357
1993 Grusby MJ, Auchincloss H, Lee R, Johnson RS, Spencer JP, Zijlstra M, Jaenisch R, Papaioannou VE, Glimcher LH. Mice lacking major histocompatibility complex class I and class II molecules. Proceedings of the National Academy of Sciences of the United States of America. 90: 3913-7. PMID 8483910 DOI: 10.1073/Pnas.90.9.3913  0.38
1993 Auchincloss H, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 3373-7. PMID 8475083 DOI: 10.1073/Pnas.90.8.3373  0.332
1993 Markowitz JS, Auchincloss H, Grusby MJ, Glimcher LH. Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 90: 2779-2783. PMID 8464889 DOI: 10.1073/Pnas.90.7.2779  0.372
1993 Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, Tonegawa S. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell. 75: 274-82. PMID 8104709 DOI: 10.1016/0092-8674(93)80069-Q  0.367
1993 Laufer TM, von Herrath MG, Grusby MJ, Oldstone MB, Glimcher LH. Autoimmune diabetes can be induced in transgenic major histocompatibility complex class II-deficient mice. The Journal of Experimental Medicine. 178: 589-96. PMID 8101862 DOI: 10.1084/Jem.178.2.589  0.348
1993 Crump AL, Grusby MJ, Glimcher LH, Cantor H. Thymocyte development in major histocompatibility complex-deficient mice: Evidence for stochastic commitment to the CD4 and CD8 lineages Proceedings of the National Academy of Sciences of the United States of America. 90: 10739-10743. PMID 7902569 DOI: 10.1073/Pnas.90.22.10739  0.367
1991 Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH. Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice Science. 253: 1417-1420. PMID 1910207 DOI: 10.1126/Science.1910207  0.395
1990 Grusby MJ, Mitchell SC, Nabavi N, Glimcher LH. Casein expression in cytotoxic T lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 87: 6897-6901. PMID 2395885 DOI: 10.1073/Pnas.87.17.6897  0.306
1990 Grusby MJ, Nabavi N, Wong H, Dick RF, Bluestone JA, Schotz MC, Glimcher LH. Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase Cell. 60: 451-459. PMID 2302735 DOI: 10.1016/0092-8674(90)90596-7  0.532
1990 Nabavi N, Grusby MJ, Finn PW, Wolgemuth DJ, Glimcher LH. Identification of an Il-4-Inducible Gene Expressed in Differentiating Lymphocytes and Male Germ Cells Developmental Immunology. 1: 19-30. PMID 2136202 DOI: 10.1155/1990/94056  0.472
1988 Pierce SK, Morris JF, Grusby MJ, Kaumaya P, van Buskirk A, Srinivasan M, Crump B, Smolenski LA. Antigen-presenting function of B lymphocytes. Immunological Reviews. 106: 149-80. PMID 3075588 DOI: 10.1111/J.1600-065X.1988.Tb00778.X  0.337
1986 Grusby MJ, Pierce SK. Induction of antigen-specific antibody responses by nonspecific T cell-derived helper factors Immunologic Research. 5: 201-209. PMID 2952746 DOI: 10.1007/Bf02919201  0.331
1984 Jelachich ML, Grusby MJ, Clark D, Tasch D, Margoliash E, Pierce SK. Synergistic effects of antigen and soluble T-cell factors in B-lymphocyte activation Proceedings of the National Academy of Sciences of the United States of America. 81: 5537-5541. PMID 6089211 DOI: 10.1073/Pnas.81.17.5537  0.361
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