Raghu Kalluri - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Cell Biology

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, ... Kalluri R, et al. Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 38017076 DOI: 10.1038/s41591-023-02694-w  0.624
2023 Kugeratski FG, LeBleu VS, Dowlatshahi DP, Sugimoto H, Arian KA, Fan Y, Huang L, Wells D, Lilla S, Hodge K, Zanivan S, McAndrews KM, Kalluri R. Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity. Biorxiv : the Preprint Server For Biology. PMID 37961535 DOI: 10.1101/2023.11.02.565371  0.632
2023 Thorlacius-Ussing J, Jensen C, Nissen NI, Cox TR, Kalluri R, Karsdal M, Willumsen N. The collagen landscape in cancer: profiling collagens in tumors and in circulation reveals novel markers of cancer-associated fibroblast subtypes. The Journal of Pathology. PMID 37728068 DOI: 10.1002/path.6207  0.318
2023 Mahadevan KK, LeBleu VS, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M, Ying H, Jain AK, DePinho RA, Maitra A, ... ... Kalluri R, et al. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8 T cells. Developmental Cell. PMID 37625403 DOI: 10.1016/j.devcel.2023.07.025  0.641
2023 Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, ... ... Kalluri R, et al. KRAS inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8 T cells. Cancer Cell. PMID 37625401 DOI: 10.1016/j.ccell.2023.07.002  0.648
2023 LeBleu VS, Dai J, Tsutakawa S, MacDonald BA, Alge JL, Sund M, Xie L, Sugimoto H, Tainer J, Zon LI, Kalluri R. Identification of unique α4 chain structure and conserved antiangiogenic activity of α3NC1 type IV collagen in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 37002899 DOI: 10.1002/dvdy.590  0.578
2023 Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Sugimoto H, ... ... Kalluri R, et al. Oncogenic Kras specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 T cells dependent manner. Biorxiv : the Preprint Server For Biology. PMID 36824971 DOI: 10.1101/2023.02.15.528757  0.655
2022 Haltom AR, Hassen WE, Hensel J, Kim J, Sugimoto H, Li B, McAndrews KM, Conner MR, Kirtley ML, Luo X, Xie B, Volpert OV, Olalekan S, Maltsev N, Basu A, ... ... Kalluri R, et al. Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma. Extracellular Vesicle. 1. PMID 37503329 DOI: 10.1016/j.vesic.2022.100014  0.649
2022 Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Author Correction: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. PMID 36198804 DOI: 10.1038/s41586-022-05062-9  0.616
2022 Chen Y, Yang S, Tavormina J, Tampe D, Zeisberg M, Wang H, Mahadevan KK, Wu CJ, Sugimoto H, Chang CC, Jenq RR, McAndrews KM, Kalluri R. Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer. Cancer Cell. PMID 35868307 DOI: 10.1016/j.ccell.2022.06.011  0.326
2022 McAndrews KM, Chen Y, Darpolor JK, Zheng X, Yang S, Carstens JL, Li B, Wang H, Miyake T, Correa de Sampaio P, Kirtley ML, Natale M, Wu CC, Sugimoto H, LeBleu VS, ... Kalluri R, et al. Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL-6 Mediated Therapy Resistance in Pancreatic Cancer. Cancer Discovery. PMID 35348629 DOI: 10.1158/2159-8290.CD-20-1484  0.658
2022 McAndrews KM, Miyake T, Ehsanipour EA, Kelly PJ, Becker LM, McGrail DJ, Sugimoto H, LeBleu VS, Ge Y, Kalluri R. Dermal αSMA myofibroblasts orchestrate skin wound repair via β1 integrin and independent of type I collagen production. The Embo Journal. e109470. PMID 35212000 DOI: 10.15252/embj.2021109470  0.592
2022 El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, ... ... Kalluri R, et al. Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2. Nature Communications. 13: 405. PMID 35058437 DOI: 10.1038/s41467-021-27893-2  0.594
2021 Zhou X, Kurywchak P, Wolf-Dennen K, Che SPY, Sulakhe D, D'Souza M, Xie B, Maltsev N, Gilliam TC, Wu CC, McAndrews KM, LeBleu VS, McConkey DJ, Volpert OV, Pretzsch SM, ... ... Kalluri R, et al. Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer. Molecular Therapy. Methods & Clinical Development. 22: 360-376. PMID 34514028 DOI: 10.1016/j.omtm.2021.05.010  0.636
2021 McAndrews KM, Xiao F, Chronopoulos A, LeBleu VS, Kugeratski FG, Kalluri R. Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic Kras in pancreatic cancer. Life Science Alliance. 4. PMID 34282051 DOI: 10.26508/lsa.202000875  0.639
2021 McAndrews KM, Vázquez-Arreguín K, Kwak C, Sugimoto H, Zheng X, Li B, Kirtley ML, LeBleu VS, Kalluri R. αSMA fibroblasts suppress Lgr5 cancer stem cells and restrain colorectal cancer progression. Oncogene. PMID 34108617 DOI: 10.1038/s41388-021-01866-7  0.684
2021 Tang M, Chen Y, Li B, Sugimoto H, Yang S, Yang C, LeBleu VS, McAndrews KM, Kalluri R. Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21557. PMID 33855751 DOI: 10.1096/fj.202002777RR  0.618
2021 Carstens JL, Yang S, Correa de Sampaio P, Zheng X, Barua S, McAndrews KM, Rao A, Burks JK, Rhim AD, Kalluri R. Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer. Cell Reports. 35: 108990. PMID 33852841 DOI: 10.1016/j.celrep.2021.108990  0.325
2021 McAndrews KM, Che SPY, LeBleu VS, Kalluri R. Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances anti-tumor immunity. The Journal of Biological Chemistry. 100523. PMID 33711340 DOI: 10.1016/j.jbc.2021.100523  0.658
2021 Chen Y, Kim J, Yang S, Wang H, Wu CJ, Sugimoto H, LeBleu VS, Kalluri R. Type I collagen deletion in αSMA myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer. Cancer Cell. PMID 33667385 DOI: 10.1016/j.ccell.2021.02.007  0.682
2020 Hensel J, McAndrews KM, McGrail DJ, Dowlatshahi DP, LeBleu VS, Kalluri R. Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses. Scientific Reports. 10: 18377. PMID 33110184 DOI: 10.1038/s41598-020-75491-x  0.545
2020 Kugeratski FG, Kalluri R. Exosomes as Mediators of Immune Regulation and Immunotherapy in Cancer. The Febs Journal. PMID 32910536 DOI: 10.1111/febs.15558  0.313
2020 McAndrews KM, Dowlatshahi DP, Dai J, Becker LM, Hensel J, Snowden LM, Leveille JM, Brunner MR, Holden K, Hopkins NS, Harris A, Kumpati JJ, Whitt MA, Lee JJ, Ostrosky-Zeichner L, ... ... Kalluri R, et al. Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications on COVID-19 immunity. Jci Insight. PMID 32796155 DOI: 10.1172/Jci.Insight.142386  0.562
2020 Lovisa S, Fletcher-Sananikone E, Sugimoto H, Hensel J, Lahiri S, Hertig A, Taduri G, Lawson E, Dewar R, Revuelta I, Kato N, Wu CJ, Bassett RL, Putluri N, Zeisberg M, ... ... Kalluri R, et al. Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Science Signaling. 13. PMID 32518142 DOI: 10.1126/Scisignal.Aaz2597  0.673
2020 Becker LM, O'Connell JT, Vo AP, Cain MP, Tampe D, Bizarro L, Sugimoto H, McGow AK, Asara JM, Lovisa S, McAndrews KM, Zielinski R, Lorenzi PL, Zeisberg M, Raza S, ... ... Kalluri R, et al. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Reports. 31: 107701. PMID 32492417 DOI: 10.1016/J.Celrep.2020.107701  0.668
2020 LeBleu VS, Kalluri R. Exosomes as a Multicomponent Biomarker Platform in Cancer. Trends in Cancer. PMID 32307267 DOI: 10.1016/J.Trecan.2020.03.007  0.661
2020 Kalluri R, LeBleu VS. The biology function and biomedical applications of exosomes. Science (New York, N.Y.). 367. PMID 32029601 DOI: 10.1126/science.aau6977  0.6
2020 Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, ... ... Kalluri R, et al. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. PMID 31942075 DOI: 10.1038/S41586-019-1922-8  0.62
2019 McAndrews KM, LeBleu VS, Kalluri R. SIRT1 Regulates Lysosome Function and Exosome Secretion. Developmental Cell. 49: 302-303. PMID 31063745 DOI: 10.1016/J.Devcel.2019.04.024  0.64
2019 McAndrews KM, Kalluri R. Nischarin Regulates Secretion of Exosomes and Cancer Progression. Cancer Research. 79: 2099-2101. PMID 31043427 DOI: 10.1158/0008-5472.CAN-19-0387  0.342
2019 LeBleu VS, Kalluri R. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 50: 547-549. PMID 30893584 DOI: 10.1016/J.Immuni.2019.02.019  0.621
2018 Chen Y, Keskin D, Sugimoto H, Kanasaki K, Phillips PE, Bizarro L, Sharpe A, LeBleu VS, Kalluri R. Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. Plos Biology. 16: e2005907. PMID 30592710 DOI: 10.1371/Journal.Pbio.2005907  0.672
2018 Parchem JG, Kanasaki K, Kanasaki M, Sugimoto H, Xie L, Hamano Y, Lee SB, Gattone VH, Parry S, Strauss JF, Garovic VD, McElrath TF, Lu KH, Sibai BM, LeBleu VS, ... ... Kalluri R, et al. Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice. The Journal of Clinical Investigation. PMID 30179860 DOI: 10.1172/Jci99026  0.632
2018 Chen Y, LeBleu VS, Carstens JL, Sugimoto H, Zheng X, Malasi S, Saur D, Kalluri R. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. Embo Molecular Medicine. PMID 30120146 DOI: 10.15252/emmm.201809085  0.662
2018 Eikesdal HP, Becker LM, Teng Y, Kizu A, Carstens JL, Kanasaki K, Sugimoto H, LeBleu VS, Kalluri R. BMP7 Signaling in TGFBR2-deficient Stromal Cells Provokes Epithelial Carcinogenesis. Molecular Cancer Research : McR. PMID 29934328 DOI: 10.1158/1541-7786.Mcr-18-0120  0.699
2018 LeBleu VS, Kalluri R. A peek into cancer-associated fibroblasts: origins, functions and translational impact. Disease Models & Mechanisms. 11. PMID 29686035 DOI: 10.1242/Dmm.029447  0.701
2018 Mendt M, Kamerkar S, Sugimoto H, McAndrews KM, Wu CC, Gagea M, Yang S, Blanko EVR, Peng Q, Ma X, Marszalek JR, Maitra A, Yee C, Rezvani K, Shpall E, ... ... Kalluri R, et al. Generation and testing of clinical-grade exosomes for pancreatic cancer. Jci Insight. 3. PMID 29669940 DOI: 10.1172/Jci.Insight.99263  0.653
2017 Kamerkar S, LeBleu VS, Sugimoto H, Yang S, Ruivo CF, Melo SA, Lee JJ, Kalluri R. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. PMID 28607485 DOI: 10.1038/nature22341  0.651
2017 Carstens JL, Correa de Sampaio P, Yang D, Barua S, Wang H, Rao A, Allison JP, LeBleu VS, Kalluri R. Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer. Nature Communications. 8: 15095. PMID 28447602 DOI: 10.1038/Ncomms15095  0.613
2017 Kalluri R, LeBleu VS. Discovery of Double-Stranded Genomic DNA in Circulating Exosomes. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28424339 DOI: 10.1101/sqb.2016.81.030932  0.644
2017 Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, Melo SA, LeBleu VS, Kalluri R. Detection of Mutant KRAS and TP53 DNA in Circulating Exosomes from Healthy Individuals and Patients with Pancreatic Cancer. Cancer Biology & Therapy. 0. PMID 28121262 DOI: 10.1080/15384047.2017.1281499  0.593
2016 Kalluri R. The biology and function of fibroblasts in cancer. Nature Reviews. Cancer. 16: 582-98. PMID 27550820 DOI: 10.1038/Nrc.2016.73  0.399
2016 Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, ... Kalluri R, et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 27089513 DOI: 10.1038/Nm.4082  0.676
2016 Kalluri R. The biology and function of exosomes in cancer. The Journal of Clinical Investigation. 126: 1208-15. PMID 27035812 DOI: 10.1172/Jci81135  0.408
2015 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... Kalluri R, et al. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 28: 831-833. PMID 28843279 DOI: 10.1016/J.Ccell.2015.11.002  0.663
2015 Cleland TP, Schroeter ER, Zamdborg L, Zheng W, Lee JE, Tran JC, Bern M, Duncan MB, Lebleu VS, Ahlf DR, Thomas PM, Kalluri R, Kelleher NL, Schweitzer MH. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. Journal of Proteome Research. PMID 26595531 DOI: 10.1021/Acs.Jproteome.5B00675  0.612
2015 Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature. PMID 26560028 DOI: 10.1038/Nature16064  0.705
2015 Lovisa S, LeBleu VS, Tampe B, Sugimoto H, Vadnagara K, Carstens JL, Wu CC, Hagos Y, Burckhardt BC, Pentcheva-Hoang T, Nischal H, Allison JP, Zeisberg M, Kalluri R. Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis. Nature Medicine. PMID 26236991 DOI: 10.1038/Nm.3902  0.668
2015 Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. PMID 26106858 DOI: 10.1038/Nature14581  0.64
2015 Keskin D, Kim J, Cooke VG, Wu CC, Sugimoto H, Gu C, De Palma M, Kalluri R, LeBleu VS. Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. Cell Reports. 10: 1066-81. PMID 25704811 DOI: 10.1016/j.celrep.2015.01.035  0.659
2014 LeBleu VS, O'Connell JT, Gonzalez Herrera KN, Wikman H, Pantel K, Haigis MC, de Carvalho FM, Damascena A, Domingos Chinen LT, Rocha RM, Asara JM, Kalluri R. PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis. Nature Cell Biology. 16: 992-1003, 1-15. PMID 25241037 DOI: 10.1038/Ncb3039  0.689
2014 Zeisberg M, Tampe B, LeBleu V, Tampe D, Zeisberg EM, Kalluri R. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. The American Journal of Pathology. 184: 2687-98. PMID 25111226 DOI: 10.1016/j.ajpath.2014.06.014  0.617
2014 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... Kalluri R, et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 25: 719-34. PMID 24856586 DOI: 10.1016/J.Ccr.2014.04.005  0.68
2014 Ayala de la Peña F, Kanasaki K, Kanasaki M, Vong S, Rovira C, Kalluri R. Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects. Plos One. 9: e95888. PMID 24760005 DOI: 10.1371/journal.pone.0095888  0.556
2014 Carstens JL, Lovisa S, Kalluri R. Microenvironment-dependent cues trigger miRNA-regulated feedback loop to facilitate the EMT/MET switch. The Journal of Clinical Investigation. 124: 1458-60. PMID 24642461 DOI: 10.1172/Jci75239  0.369
2014 Tampe B, Tampe D, Müller CA, Sugimoto H, LeBleu V, Xu X, Müller GA, Zeisberg EM, Kalluri R, Zeisberg M. Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. Journal of the American Society of Nephrology : Jasn. 25: 905-12. PMID 24480825 DOI: 10.1681/ASN.2013070723  0.628
2014 LeBleu VS, O'Connell JT, Herrera KNG, Wikman H, Pantel K, Haigis MC, de Carvalho FM, Damascena A, Chinen LTD, Rocha RM, Asara JM, Kalluri R. Erratum: Corrigendum: PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis Nature Cell Biology. 16: 1125-1125. DOI: 10.1038/Ncb3056  0.645
2013 Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nature Medicine. 19: 810-1. PMID 23836214 DOI: 10.1038/Nm.3081  0.595
2013 LeBleu VS, Taduri G, O'Connell J, Teng Y, Cooke VG, Woda C, Sugimoto H, Kalluri R. Origin and function of myofibroblasts in kidney fibrosis. Nature Medicine. 19: 1047-53. PMID 23817022 DOI: 10.1038/Nm.3218  0.677
2013 Kahlert C, Kalluri R. Exosomes in tumor microenvironment influence cancer progression and metastasis. Journal of Molecular Medicine (Berlin, Germany). 91: 431-7. PMID 23519402 DOI: 10.1007/s00109-013-1020-6  0.333
2013 Melo SA, Kalluri R. miR-29b moulds the tumour microenvironment to repress metastasis. Nature Cell Biology. 15: 139-40. PMID 23377028 DOI: 10.1038/Ncb2684  0.335
2013 LeBleu VS, Teng Y, O'Connell JT, Charytan D, Müller GA, Müller CA, Sugimoto H, Kalluri R. Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. Nature Medicine. 19: 227-31. PMID 23353556 DOI: 10.1038/Nm.2989  0.661
2013 Borges FT, Melo SA, Özdemir BC, Kato N, Revuelta I, Miller CA, Gattone VH, LeBleu VS, Kalluri R. TGF-β1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. Journal of the American Society of Nephrology : Jasn. 24: 385-92. PMID 23274427 DOI: 10.1681/Asn.2012101031  0.66
2012 Kieran MW, Kalluri R, Cho YJ. The VEGF pathway in cancer and disease: responses, resistance, and the path forward. Cold Spring Harbor Perspectives in Medicine. 2: a006593. PMID 23209176 DOI: 10.1101/Cshperspect.A006593  0.35
2012 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W. Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Reports. 2: 52-61. PMID 22840396 DOI: 10.1016/J.Celrep.2012.06.002  0.322
2012 Medici D, Kalluri R. Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype. Seminars in Cancer Biology. 22: 379-84. PMID 22554794 DOI: 10.1016/J.Semcancer.2012.04.004  0.365
2012 Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nature Medicine. 18: 396-404. PMID 22306733 DOI: 10.1038/Nm.2629  0.662
2012 Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 21: 66-81. PMID 22264789 DOI: 10.1016/J.Ccr.2011.11.024  0.784
2012 Laklai H, Kalluri R, Moses H, Weaver V, Ijichi H, Lakins J, Miroshnikova Y, Acerbi I, Lopez J, Kassianidou E, Gorska A, Novitskiy S. Abstract A47: Reciprocal dialogue between cellular and extracellular matrix tension and tissue inflammation in pancreatic tumor progression. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A47  0.424
2011 Vong S, Kalluri R. The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis. Genes & Cancer. 2: 1139-45. PMID 22866205 DOI: 10.1177/1947601911423940  0.638
2011 LeBleu VS, Kalluri R. Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney International. 80: 1119-21. PMID 22083636 DOI: 10.1038/ki.2011.300  0.616
2011 O'Connell JT, Sugimoto H, Cooke VG, MacDonald BA, Mehta AI, LeBleu VS, Dewar R, Rocha RM, Brentani RR, Resnick MB, Neilson EG, Zeisberg M, Kalluri R. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proceedings of the National Academy of Sciences of the United States of America. 108: 16002-7. PMID 21911392 DOI: 10.1073/Pnas.1109493108  0.704
2011 De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, et al. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 20: 400-13. PMID 21907929 DOI: 10.1016/J.Ccr.2011.08.014  0.628
2011 Tse JC, Kalluri R. Waking up dormant tumors. Breast Cancer Research : Bcr. 13: 310. PMID 21672272 DOI: 10.1186/Bcr2872  0.802
2011 Xie L, Duncan MB, Pahler J, Sugimoto H, Martino M, Lively J, Mundel T, Soubasakos M, Rubin K, Takeda T, Inoue M, Lawler J, Hynes RO, Hanahan D, Kalluri R. Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 9939-44. PMID 21622854 DOI: 10.1073/Pnas.1105041108  0.418
2011 Medici D, Potenta S, Kalluri R. Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling. The Biochemical Journal. 437: 515-20. PMID 21585337 DOI: 10.1042/Bj20101500  0.768
2011 Ayala de la Peña F, Kanasaki K, Kanasaki M, Tangirala N, Maeda G, Kalluri R. Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma. The Journal of Biological Chemistry. 286: 20778-87. PMID 21388952 DOI: 10.1074/Jbc.M110.198069  0.38
2011 Teng Y, Kanasaki K, Bardeesy N, Sugimoto H, Kalluri R. Deletion of Smad4 in fibroblasts leads to defective chondrocyte maturation and cartilage production in a TGFβ type II receptor independent manner. Biochemical and Biophysical Research Communications. 407: 633-9. PMID 21376704 DOI: 10.1016/J.Bbrc.2011.02.142  0.331
2011 Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, ... ... Kalluri R, et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proceedings of the National Academy of Sciences of the United States of America. 108: 4394-9. PMID 21368194 DOI: 10.1073/Pnas.1014720108  0.302
2011 Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR. Erratum: Corrigendum: Conversion of vascular endothelial cells into multipotent stem-like cells Nature Medicine. 17: 514-514. DOI: 10.1038/Nm0411-514D  0.304
2010 LeBleu V, Sund M, Sugimoto H, Birrane G, Kanasaki K, Finan E, Miller CA, Gattone VH, McLaughlin H, Shield CF, Kalluri R. Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly. The Journal of Biological Chemistry. 285: 41874-85. PMID 20847057 DOI: 10.1074/Jbc.M110.149534  0.609
2010 Wiig H, Keskin D, Kalluri R. Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 645-56. PMID 20727409 DOI: 10.1016/J.Matbio.2010.08.001  0.35
2010 Wiig H, Tenstad O, Iversen PO, Kalluri R, Bjerkvig R. Interstitial fluid: the overlooked component of the tumor microenvironment? Fibrogenesis & Tissue Repair. 3: 12. PMID 20653943 DOI: 10.1186/1755-1536-3-12  0.327
2010 Hamano Y, Okude T, Shirai R, Sato I, Kimura R, Ogawa M, Ueda Y, Yokosuka O, Kalluri R, Ueda S. Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis. Journal of the American Society of Nephrology : Jasn. 21: 1445-55. PMID 20616167 DOI: 10.1681/Asn.2009050492  0.356
2010 Polyak K, Kalluri R. The role of the microenvironment in mammary gland development and cancer. Cold Spring Harbor Perspectives in Biology. 2: a003244. PMID 20591988 DOI: 10.1101/cshperspect.a003244  0.311
2010 Bechtel W, McGoohan S, Zeisberg EM, Müller GA, Kalbacher H, Salant DJ, Müller CA, Kalluri R, Zeisberg M. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nature Medicine. 16: 544-50. PMID 20418885 DOI: 10.1038/Nm.2135  0.336
2010 Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. The Journal of Biological Chemistry. 285: 20202-12. PMID 20363741 DOI: 10.1074/Jbc.M110.102012  0.38
2009 LeBleu V, Sugimoto H, Mundel TM, Gerami-Naini B, Finan E, Miller CA, Gattone VH, Lu L, Shield CF, Folkman J, Kalluri R. Stem cell therapies benefit Alport syndrome. Journal of the American Society of Nephrology : Jasn. 20: 2359-70. PMID 19833902 DOI: 10.1681/Asn.2009010123  0.658
2009 Ayala F, Dewar R, Kieran M, Kalluri R. Contribution of bone microenvironment to leukemogenesis and leukemia progression. Leukemia. 23: 2233-41. PMID 19727127 DOI: 10.1038/Leu.2009.175  0.364
2009 Duncan MB, Kalluri R. Parstatin, a novel protease-activated receptor 1-derived inhibitor of angiogenesis. Molecular Interventions. 9: 168-70. PMID 19720748 DOI: 10.1124/Mi.9.4.4  0.304
2009 Romagnani P, Kalluri R. Possible mechanisms of kidney repair. Fibrogenesis & Tissue Repair. 2: 3. PMID 19558670 DOI: 10.1186/1755-1536-2-3  0.339
2009 Eikesdal HP, Kalluri R. Drug resistance associated with antiangiogenesis therapy. Seminars in Cancer Biology. 19: 310-7. PMID 19524042 DOI: 10.1016/J.Semcancer.2009.05.006  0.308
2009 Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. The Journal of Clinical Investigation. 119: 1420-8. PMID 19487818 DOI: 10.1172/Jci39104  0.371
2009 Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. The Journal of Clinical Investigation. 119: 1417-9. PMID 19487817 DOI: 10.1172/Jci39675  0.4
2009 Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Research. 69: 4537-44. PMID 19435903 DOI: 10.1158/0008-5472.Can-08-4539  0.361
2009 Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, et al. Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Science (New York, N.Y.). 324: 626-31. PMID 19407199 DOI: 10.1126/Science.1165069  0.618
2009 Sund M, Kalluri R. Tumor stroma derived biomarkers in cancer. Cancer Metastasis Reviews. 28: 177-83. PMID 19259624 DOI: 10.1007/S10555-008-9175-2  0.437
2009 Tse JC, Sugimoto H, Cooke VG, MacDonald BA, Mehta AI, Neilson EG, Zeisberg M, Kalluri R. Abstract B23: Distinct roles for cancer‐associated fibroblasts in breast cancer progression and metastasis Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B23  0.775
2009 Vong S, Sugimoto H, Teng Y, Xie L, Dewar R, Kalluri R. Abstract B22: Oncogene activation of K‐ras in resident myofibroblasts leads to development of spontaneous bronchioalveolar carcinoma in mice Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-B22  0.589
2009 Bleicher M, LeBleu V, Doyle A, Kearns J, Bloom R, Tomaszewski J, Kalluri R, Kamoun M. 263-P: Acute AMR associated with anti-GBM antibodies in a kidney transplant recipient with Alport's syndrome Human Immunology. 70: S144. DOI: 10.1016/J.Humimm.2009.09.296  0.56
2008 Zavadil J, Haley J, Kalluri R, Muthuswamy SK, Thompson E. Epithelial-mesenchymal transition. Cancer Research. 68: 9574-7. PMID 19047131 DOI: 10.1158/0008-5472.Can-08-2316  0.347
2008 Cooke VG, Kalluri R. Chapter 1. Molecular mechanism of type IV collagen-derived endogenous inhibitors of angiogenesis. Methods in Enzymology. 444: 1-19. PMID 19007658 DOI: 10.1016/S0076-6879(08)02801-2  0.357
2008 Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. Journal of the American Society of Nephrology : Jasn. 19: 2282-7. PMID 18987304 DOI: 10.1681/Asn.2008050513  0.794
2008 Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R. Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity. Proceedings of the National Academy of Sciences of the United States of America. 105: 15040-5. PMID 18818312 DOI: 10.1073/Pnas.0807055105  0.347
2008 Potenta S, Zeisberg E, Kalluri R. The role of endothelial-to-mesenchymal transition in cancer progression. British Journal of Cancer. 99: 1375-9. PMID 18797460 DOI: 10.1038/Sj.Bjc.6604662  0.8
2008 Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R. Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor. Experimental Cell Research. 314: 3292-305. PMID 18775695 DOI: 10.1016/J.Yexcr.2008.08.011  0.396
2008 LeBleu VS, Kalluri R. Stem cell-based therapy for glomerular diseases: an evolving concept. Journal of the American Society of Nephrology : Jasn. 19: 1621-3. PMID 18701605 DOI: 10.1681/Asn.2008070735  0.634
2008 Zeisberg M, Kalluri R. Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis. Frontiers in Bioscience : a Journal and Virtual Library. 13: 6991-8. PMID 18508710 DOI: 10.2741/3204  0.331
2008 Zeisberg M, Kalluri R. Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease. Pediatric Nephrology (Berlin, Germany). 23: 1395-8. PMID 18446379 DOI: 10.1007/S00467-008-0818-X  0.309
2008 Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. Experimental Biology and Medicine (Maywood, N.J.). 233: 155-62. PMID 18222970 DOI: 10.3181/0706-Rm-167  0.788
2008 Lebleu VS, Sugimoto H, Miller CA, Gattone VH, Kalluri R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 284-92. PMID 18180701 DOI: 10.1038/Labinvest.3700715  0.657
2008 Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, ... ... Kalluri R, et al. Modification of kidney barrier function by the urokinase receptor. Nature Medicine. 14: 55-63. PMID 18084301 DOI: 10.1038/Nm1696  0.363
2008 Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH, Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Developmental Biology. 313: 584-93. PMID 18082680 DOI: 10.1016/J.Ydbio.2007.10.047  0.638
2008 Mundel TM, Yliniemi AM, Maeshima Y, Sugimoto H, Kieran M, Kalluri R. Type IV collagen alpha6 chain-derived noncollagenous domain 1 (alpha6(IV)NC1) inhibits angiogenesis and tumor growth. International Journal of Cancer. Journal International Du Cancer. 122: 1738-44. PMID 18074349 DOI: 10.1002/Ijc.23269  0.369
2007 Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Research. 67: 10123-8. PMID 17974953 DOI: 10.1158/0008-5472.Can-07-3127  0.82
2007 LeBleu VS, Macdonald B, Kalluri R. Structure and function of basement membranes. Experimental Biology and Medicine (Maywood, N.J.). 232: 1121-9. PMID 17895520 DOI: 10.3181/0703-Mr-72  0.647
2007 Mundel TM, Kalluri R. Type IV collagen-derived angiogenesis inhibitors. Microvascular Research. 74: 85-9. PMID 17602710 DOI: 10.1016/J.Mvr.2007.05.005  0.337
2007 Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. The Journal of Biological Chemistry. 282: 23337-47. PMID 17562716 DOI: 10.1074/Jbc.M700194200  0.341
2007 Teng Y, Zeisberg M, Kalluri R. Transcriptional regulation of epithelial-mesenchymal transition. The Journal of Clinical Investigation. 117: 304-6. PMID 17273552 DOI: 10.1172/Jci31200  0.33
2007 Tse JC, Kalluri R. Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. Journal of Cellular Biochemistry. 101: 816-29. PMID 17243120 DOI: 10.1002/Jcb.21215  0.805
2007 Sugimoto H, Yang C, LeBleu VS, Soubasakos MA, Giraldo M, Zeisberg M, Kalluri R. BMP-7 functions as a novel hormone to facilitate liver regeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 256-64. PMID 17116741 DOI: 10.1096/Fj.06-6837Com  0.622
2007 Thompson EW, Savagner P, Dedhar S, Kalluri R. Epithelial-mesenchymal transitions - New insights into signaling, development and pathogenesis Cells Tissues Organs. 185: 5-6. DOI: 10.1159/000104413  0.389
2006 Sugimoto H, Mundel TM, Kieran MW, Kalluri R. Identification of fibroblast heterogeneity in the tumor microenvironment. Cancer Biology & Therapy. 5: 1640-6. PMID 17106243 DOI: 10.4161/Cbt.5.12.3354  0.442
2006 Kalluri R. Proteinuria with and without renal glomerular podocyte effacement. Journal of the American Society of Nephrology : Jasn. 17: 2383-9. PMID 16914535 DOI: 10.1681/Asn.2006060628  0.334
2006 Farazi PA, Zeisberg M, Glickman J, Zhang Y, Kalluri R, DePinho RA. Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice. Cancer Research. 66: 6622-7. PMID 16818635 DOI: 10.1158/0008-5472.Can-05-4609  0.345
2006 Kalluri R, Zeisberg M. Fibroblasts in cancer. Nature Reviews. Cancer. 6: 392-401. PMID 16572188 DOI: 10.1038/Nrc1877  0.428
2006 Tanjore H, Kalluri R. The role of type IV collagen and basement membranes in cancer progression and metastasis. The American Journal of Pathology. 168: 715-7. PMID 16507886 DOI: 10.2353/Ajpath.2006.051321  0.378
2006 Zeisberg M, Kramer K, Sindhi N, Sarkar P, Upton M, Kalluri R. De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane. Molecular and Cellular Biochemistry. 283: 181-9. PMID 16444601 DOI: 10.1007/S11010-006-2677-8  0.303
2006 Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP. Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. The Journal of Biological Chemistry. 281: 6020-9. PMID 16365041 DOI: 10.1074/Jbc.M509134200  0.373
2005 Okada H, Kalluri R. Cellular and molecular pathways that lead to progression and regression of renal fibrogenesis. Current Molecular Medicine. 5: 467-74. PMID 16101477 DOI: 10.2174/1566524054553478  0.357
2005 Hamano Y, Kalluri R. Tumstatin, the NC1 domain of alpha3 chain of type IV collagen, is an endogenous inhibitor of pathological angiogenesis and suppresses tumor growth. Biochemical and Biophysical Research Communications. 333: 292-8. PMID 15979458 DOI: 10.1016/J.Bbrc.2005.05.130  0.42
2005 Nyberg P, Xie L, Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Research. 65: 3967-79. PMID 15899784 DOI: 10.1158/0008-5472.Can-04-2427  0.365
2005 Sund M, Hamano Y, Sugimoto H, Sudhakar A, Soubasakos M, Yerramalla U, Benjamin LE, Lawler J, Kieran M, Shah A, Kalluri R. Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors. Proceedings of the National Academy of Sciences of the United States of America. 102: 2934-9. PMID 15710885 DOI: 10.1073/Pnas.0500180102  0.409
2005 Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. The Journal of Biological Chemistry. 280: 8094-100. PMID 15591043 DOI: 10.1074/Jbc.M413102200  0.323
2005 Kalluri R. Cardiac and renal cell lineage derived from stem cells: Implication for organ regeneration Kidney International. 68: 1965. DOI: 10.1038/Ki.2005.18  0.336
2004 Sund M, Xie L, Kalluri R. The contribution of vascular basement membranes and extracellular matrix to the mechanics of tumor angiogenesis. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 112: 450-62. PMID 15563309 DOI: 10.1111/J.1600-0463.2004.T01-1-Apm11207-0806.X  0.34
2004 Hamano Y, Sugimoto H, Soubasakos MA, Kieran M, Olsen BR, Lawler J, Sudhakar A, Kalluri R. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Research. 64: 1570-4. PMID 14996710 DOI: 10.1158/0008-5472.Can-03-3126  0.406
2004 Folkman J, Kalluri R. Cancer without disease. Nature. 427: 787. PMID 14985739 DOI: 10.1038/427787A  0.339
2003 Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. The Journal of Clinical Investigation. 112: 1776-84. PMID 14679171 DOI: 10.1172/Jci20530  0.354
2003 Salama AD, Chaudhry AN, Holthaus KA, Mosley K, Kalluri R, Sayegh MH, Lechler RI, Pusey CD, Lightstone L. Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease. Kidney International. 64: 1685-94. PMID 14531801 DOI: 10.1046/J.1523-1755.2003.00259.X  0.327
2003 Zeisberg M, Bottiglio C, Kumar N, Maeshima Y, Strutz F, Müller GA, Kalluri R. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. American Journal of Physiology. Renal Physiology. 285: F1060-7. PMID 12915382 DOI: 10.1152/Ajprenal.00191.2002  0.3
2003 Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R. Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer Cell. 3: 589-601. PMID 12842087 DOI: 10.1016/S1535-6108(03)00133-8  0.388
2003 McDonald GA, Sarkar P, Rennke H, Unemori E, Kalluri R, Sukhatme VP. Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo. American Journal of Physiology. Renal Physiology. 285: F59-67. PMID 12820641 DOI: 10.1152/Ajprenal.00157.2002  0.306
2003 Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nature Medicine. 9: 964-8. PMID 12808448 DOI: 10.1038/Nm888  0.338
2003 Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nature Reviews. Cancer. 3: 422-33. PMID 12778132 DOI: 10.1038/Nrc1094  0.369
2003 Sugimoto H, Hamano Y, Charytan D, Cosgrove D, Kieran M, Sudhakar A, Kalluri R. Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. The Journal of Biological Chemistry. 278: 12605-8. PMID 12538598 DOI: 10.1074/Jbc.C300012200  0.328
2002 Natoli TA, Liu J, Eremina V, Hodgens K, Li C, Hamano Y, Mundel P, Kalluri R, Miner JH, Quaggin SE, Kreidberg JA. A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development. Journal of the American Society of Nephrology : Jasn. 13: 2058-67. PMID 12138137 DOI: 10.1097/01.Asn.0000022420.48110.4B  0.371
2002 Zeisberg M, Maeshima Y, Mosterman B, Kalluri R. Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. The American Journal of Pathology. 160: 2001-8. PMID 12057905 DOI: 10.1016/S0002-9440(10)61150-9  0.352
2002 Strutz F, Zeisberg M, Ziyadeh FN, Yang CQ, Kalluri R, Müller GA, Neilson EG. Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney International. 61: 1714-28. PMID 11967021 DOI: 10.1046/J.1523-1755.2002.00333.X  0.36
2002 Maeshima Y, Sudhakar A, Lively JC, Ueki K, Kharbanda S, Kahn CR, Sonenberg N, Hynes RO, Kalluri R. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science (New York, N.Y.). 295: 140-3. PMID 11778052 DOI: 10.1126/Science.1065298  0.312
2001 Zeisberg M, Bonner G, Maeshima Y, Colorado P, Müller GA, Strutz F, Kalluri R. Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation. The American Journal of Pathology. 159: 1313-21. PMID 11583959 DOI: 10.1016/S0002-9440(10)62518-7  0.354
2001 Maeshima Y, Manfredi M, Reimer C, Holthaus KA, Hopfer H, Chandamuri BR, Kharbanda S, Kalluri R. Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin. The Journal of Biological Chemistry. 276: 15240-8. PMID 11278365 DOI: 10.1074/Jbc.M007764200  0.406
2000 Cosgrove D, Rodgers K, Meehan D, Miller C, Bovard K, Gilroy A, Gardner H, Kotelianski V, Gotwals P, Amatucci A, Kalluri R. Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy. The American Journal of Pathology. 157: 1649-59. PMID 11073824 DOI: 10.1016/S0002-9440(10)64802-X  0.331
2000 Maeshima Y, Colorado PC, Kalluri R. Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties. The Journal of Biological Chemistry. 275: 23745-50. PMID 10837460 DOI: 10.1074/Jbc.C000186200  0.362
2000 Maeshima Y, Colorado PC, Torre A, Holthaus KA, Grunkemeyer JA, Ericksen MB, Hopfer H, Xiao Y, Stillman IE, Kalluri R. Distinct antitumor properties of a type IV collagen domain derived from basement membrane. The Journal of Biological Chemistry. 275: 21340-8. PMID 10766752 DOI: 10.1074/Jbc.M001956200  0.345
2000 Kalluri R, Cantley LG, Kerjaschki D, Neilson EG. Reactive oxygen species expose cryptic epitopes associated with autoimmune goodpasture syndrome. The Journal of Biological Chemistry. 275: 20027-32. PMID 10748075 DOI: 10.1074/Jbc.M904549199  0.306
2000 Kamphaus GD, Colorado PC, Panka DJ, Hopfer H, Ramchandran R, Torre A, Maeshima Y, Mier JW, Sukhatme VP, Kalluri R. Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. The Journal of Biological Chemistry. 275: 1209-15. PMID 10625665 DOI: 10.1074/Jbc.275.2.1209  0.401
1996 Lei H, Furth EE, Kalluri R, Chiou T, Tilly KI, Tilly JL, Elkon KB, Jeffrey JJ, Strauss JF. A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor. The Journal of Clinical Investigation. 98: 1971-8. PMID 8903315 DOI: 10.1172/Jci119001  0.31
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