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Michelle Krogsgaard - Publications

Affiliations: 
Basic Medical Science New York University, New York, NY, United States 
Area:
Oncology, Immunology, Molecular Biology
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58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Structural basis for self-discrimination by neoantigen-specific TCRs. Nature Communications. 15: 2140. PMID 38459027 DOI: 10.1038/s41467-024-46367-9  0.343
2023 Patskovsky Y, Natarajan A, Patskovska L, Nyovanie S, Joshi B, Morin B, Brittsan C, Huber O, Gordon S, Michelet X, Schmitzberger F, Stein RB, Findeis MA, Hurwitz A, Van Dijk M, ... ... Krogsgaard M, et al. Molecular mechanism of phosphopeptide neoantigen immunogenicity. Nature Communications. 14: 3763. PMID 37353482 DOI: 10.1038/s41467-023-39425-1  0.37
2023 Finnigan J, Newman J, Patskovsky Y, Patskovska L, Ishizuka A, Lynn G, Seder R, Krogsgaard M, Bhardwaj N. Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs. Research Square. PMID 36778273 DOI: 10.21203/rs.3.rs-2531184/v1  0.373
2020 Deng J, Thennavan A, Shah S, Bagdatlioglu E, Klar N, Heguy A, Marier C, Meyn P, Zhang Y, Labbe K, Almonte C, Krogsgaard M, Perou CM, Wong KK, Adams S. Serial single-cell profiling analysis of metastatic TNBC during Nab-paclitaxel and pembrolizumab treatment. Breast Cancer Research and Treatment. PMID 32949350 DOI: 10.1007/S10549-020-05936-4  0.389
2020 Yoshida T, Ichikawa J, Giuroiu I, Laino AS, Hao Y, Krogsgaard M, Vassallo M, Woods DM, Stephen Hodi F, Weber J. C reactive protein impairs adaptive immunity in immune cells of patients with melanoma. Journal For Immunotherapy of Cancer. 8. PMID 32303612 DOI: 10.1136/Jitc-2019-000234  0.439
2019 Krogsgaard M, Moogk D, Li K, Yuan Z, Osman I, Weber JS, Zhu C. Abstract PR08: Mechanisms of primary resistance to PD-1 checkpoint blockade Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Pr08  0.429
2019 Deng J, Shah S, Thennavan A, Krogsgaard M, Perou CM, Wong K, Adams S. Abstract 4044: The immune phenotype in serial biopsies from metastatic TNBC undergoing chemo-immunotherapy Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-4044  0.349
2019 Moogk D, Wang L, Li K, Yuan Z, Weber J, Osman I, Zhu C, Krogsgaard M. Abstract 3236: T-cell intrinsic mechanisms of resistance to PD-1 checkpoint blockade Immunology. DOI: 10.1158/1538-7445.Sabcs18-3236  0.372
2018 Natarajan A, Krogsgaard M. The myriad targets of a T cell. Nature Biotechnology. 36: 1152-1154. PMID 30520863 DOI: 10.1038/Nbt.4309  0.499
2018 Gowen MF, Giles KM, Simpson D, Tchack J, Zhou H, Moran U, Dawood Z, Pavlick AC, Hu S, Wilson MA, Zhong H, Krogsgaard M, Kirchhoff T, Osman I. Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors. Journal of Translational Medicine. 16: 82. PMID 29606147 DOI: 10.1186/S12967-018-1452-4  0.371
2018 Moogk D, Natarajan A, Krogsgaard M. T cell receptor signal transduction: affinity, force and conformational change Current Opinion in Chemical Engineering. 19: 43-50. DOI: 10.1016/J.Coche.2017.12.007  0.544
2017 Weiss SA, Han SW, Lui K, Tchack J, Shapiro R, Berman R, Zhong J, Krogsgaard M, Osman I, Darvishian F. Corrigendum to "Immunologic heterogeneity of tumor-infiltrating lymphocyte composition in primary melanoma" (Hum Pathol 2016;57:116-25). Human Pathology. PMID 28449825 DOI: 10.1016/J.Humpath.2017.03.001  0.343
2016 Weiss SA, Han J, Darvishian F, Tchack J, Han SW, Malecek K, Krogsgaard M, Osman I, Zhong J. Impact of aging on host immune response and survival in melanoma: an analysis of 3 patient cohorts. Journal of Translational Medicine. 14: 299. PMID 27760559 DOI: 10.1186/S12967-016-1026-2  0.732
2016 Weiss SA, Han SW, Lui K, Tchack J, Shapiro R, Berman R, Zhong J, Krogsgaard M, Osman I, Darvishian F. Immunologic heterogeneity of tumor infiltrating lymphocyte composition in primary melanoma. Human Pathology. PMID 27473267 DOI: 10.1016/J.Humpath.2016.07.008  0.397
2016 Moogk D, Zhong S, Yu Z, Liadi I, Rittase W, Fang V, Dougherty J, Perez-Garcia A, Osman I, Zhu C, Varadarajan N, Restifo NP, Frey AB, Krogsgaard M. Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets. Journal of Immunology (Baltimore, Md. : 1950). PMID 27271569 DOI: 10.4049/Jimmunol.1600178  0.438
2016 Natarajan A, Nadarajah V, Felsovalyi K, Wang W, Jeyachandran VR, Wasson RA, Cardozo T, Bracken C, Krogsgaard M. Structural Model of the Extracellular Assembly of the TCR-CD3 Complex. Cell Reports. PMID 26997265 DOI: 10.1016/J.Celrep.2016.02.081  0.397
2016 Vogelsang M, Martinez CN, Rendleman J, Bapodra AB, Malecek K, Romanchuk A, Kazlow E, Shapiro RL, Berman RS, Krogsgaard M, Osman I, Kirchhoff T. The expression quantitative trait loci in immune pathways and their effect on cutaneous melanoma prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26733611 DOI: 10.1158/1078-0432.Ccr-15-2066  0.726
2016 Weiss SA, Tchack J, Han J, Darvishian F, Shapiro RL, Krogsgaard M, Zhong J, Osman I. Impact of aging on immune response and survival in melanoma. Journal of Clinical Oncology. 34: e21079-e21079. DOI: 10.1200/Jco.2016.34.15_Suppl.E21079  0.371
2015 Rendleman J, Vogelsang M, Bapodra A, Adaniel C, Silva I, Moogk D, Martinez CN, Fleming N, Shields J, Shapiro R, Berman R, Pavlick A, Polsky D, Shao Y, Osman I, ... Krogsgaard M, et al. Genetic associations of the interleukin locus at 1q32.1 with clinical outcomes of cutaneous melanoma. Journal of Medical Genetics. 52: 231-9. PMID 25604082 DOI: 10.1136/Jmedgenet-2014-102832  0.31
2015 Moogk D, Li T, Lee C, Pires Da Silva IED, Ma MW, Friedman EB, Vega-Saenz de Miera E, Darvishian F, Scanlon P, Perez-Garcia A, Pavlick AC, Bhardwaj N, Christos PJ, Osman I, Krogsgaard M. Association of melanoma expression of matrix metalloproteinase-23 with blunted tumor immunity and poor responses to immunotherapy. Journal of Clinical Oncology. 33: e20057-e20057. DOI: 10.1200/Jco.2015.33.15_Suppl.E20057  0.45
2015 Weiss SA, Han SW, Vogelsang M, Krogsgaard M, Lui KP, Shapiro RL, Kirchhoff T, Darvishian F, Osman I. Tumor infiltrating lymphocyte (TIL) classifications and association with survival in primary melanomas. Journal of Clinical Oncology. 33: e20042-e20042. DOI: 10.1200/Jco.2015.33.15_Suppl.E20042  0.379
2014 Moogk D, da Silva IP, Ma MW, Friedman EB, de Miera EV, Darvishian F, Scanlon P, Perez-Garcia A, Pavlick AC, Bhardwaj N, Christos PJ, Osman I, Krogsgaard M. Melanoma expression of matrix metalloproteinase-23 is associated with blunted tumor immunity and poor responses to immunotherapy. Journal of Translational Medicine. 12: 342. PMID 25491880 DOI: 10.1186/S12967-014-0342-7  0.449
2014 Malecek K, Grigoryan A, Zhong S, Gu WJ, Johnson LA, Rosenberg SA, Cardozo T, Krogsgaard M. Specific increase in potency via structure-based design of a TCR. Journal of Immunology (Baltimore, Md. : 1950). 193: 2587-99. PMID 25070852 DOI: 10.4049/Jimmunol.1302344  0.801
2014 Wang W, Li T, Felsovalyi K, Chen C, Cardozo T, Krogsgaard M. Quantitative analysis of T cell receptor complex interaction sites using genetically encoded photo-cross-linkers. Acs Chemical Biology. 9: 2165-72. PMID 25061810 DOI: 10.1021/Cb500351S  0.408
2014 Crites TJ, Padhan K, Muller J, Krogsgaard M, Gudla PR, Lockett SJ, Varma R. TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction. Journal of Immunology (Baltimore, Md. : 1950). 193: 56-67. PMID 24860189 DOI: 10.4049/jimmunol.1400315  0.345
2014 Krogsgaard M. Imprinting of the mature T cell response by self. Trends in Immunology. 35: 141-3. PMID 24646828 DOI: 10.1016/J.It.2014.03.002  0.49
2014 Liu B, Zhong S, Malecek K, Johnson LA, Rosenberg SA, Zhu C, Krogsgaard M. 2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system. European Journal of Immunology. 44: 239-50. PMID 24114747 DOI: 10.1002/Eji.201343774  0.779
2014 Rendleman J, Adaniel C, Kern E, Fleming NH, Krogsgaard M, Polsky D, Berman RS, Shapiro RL, Pavlick AC, Shao Y, Osman I, Kirchhoff T. The genetic variants in interleukin locus at 1q32.1 as markers of melanoma survival. Journal of Clinical Oncology. 32: 9094-9094. DOI: 10.1200/Jco.2014.32.15_Suppl.9094  0.374
2014 Fleming NH, Lui KP, Shapiro RL, Berman RS, Pavlick AC, Zhong J, Krogsgaard M, Pires Da Silva IED, Osman I. Dissecting the effect of age on immune response in melanoma patients. Journal of Clinical Oncology. 32: 9058-9058. DOI: 10.1200/Jco.2014.32.15_Suppl.9058  0.342
2014 Malecek K, Grigoryan A, Zhong S, Gu WJ, Johnson LA, Rosenberg SA, Cardozo T, Krogsgaard M. Specific increase in T-cell potency via structure-based design of a T-cell receptor for adoptive immunotherapy. Journal of Clinical Oncology. 32: 3063-3063. DOI: 10.1200/Jco.2014.32.15_Suppl.3063  0.806
2014 Moogk D, Ma MW, Pires Da Silva IED, Friedman EB, Vega-Saenz de Miera E, Darvishian F, Perez-Garcia A, Scanlon P, Pavlick AC, Bhardwaj N, Christos PJ, Osman I, Krogsgaard M. Matrix metalloproteinase-23 as a new immunotherapeutic checkpoint target in melanoma. Journal of Clinical Oncology. 32: 3030-3030. DOI: 10.1200/Jco.2014.32.15_Suppl.3030  0.452
2014 Malecek K, Grigoryan A, Zhong S, Gu WJ, Johnson LA, Rosenberg SA, Cardozo T, Krogsgaard M. Specific increase in T cell potency via structure-based design of a T cell receptor for adoptive immunotherapy Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-P28  0.787
2014 Zhong S, Malecek K, Moogk D, Johnson LA, Yu Z, Grigoryan A, Vega-Saenz de Miera E, Darvishian F, Gu W, McGary K, Huang K, Boyer J, Corse E, Yongzhao S, Rosenberg SA, ... ... Krogsgaard M, et al. Engineering the immune response to "self" for effective cancer immunotherapy Journal For Immunotherapy of Cancer. 2: P22. DOI: 10.1186/2051-1426-2-S3-P22  0.775
2013 Havukainen H, Münch D, Baumann A, Zhong S, Halskau Ø, Krogsgaard M, Amdam GV. Vitellogenin recognizes cell damage through membrane binding and shields living cells from reactive oxygen species. The Journal of Biological Chemistry. 288: 28369-81. PMID 23897804 DOI: 10.1074/Jbc.M113.465021  0.322
2013 Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman GJ, Krogsgaard M, Riley JL. Strength of PD-1 signaling differentially affects T-cell effector functions. Proceedings of the National Academy of Sciences of the United States of America. 110: E2480-9. PMID 23610399 DOI: 10.1073/Pnas.1305394110  0.421
2013 Zhong S, Malecek K, Johnson LA, Yu Z, Vega-Saenz de Miera E, Darvishian F, McGary K, Huang K, Boyer J, Corse E, Shao Y, Rosenberg SA, Restifo NP, Osman I, Krogsgaard M. T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 110: 6973-8. PMID 23576742 DOI: 10.1073/pnas.1221609110  0.811
2013 Malecek K, Zhong S, McGary K, Yu C, Huang K, Johnson LA, Rosenberg SA, Krogsgaard M. Engineering improved T cell receptors using an alanine-scan guided T cell display selection system. Journal of Immunological Methods. 392: 1-11. PMID 23500145 DOI: 10.1016/J.Jim.2013.02.018  0.801
2013 Wan Q, Kozhaya L, Imberg K, Mercer F, Zhong S, Krogsgaard M, Unutmaz D. Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors. Plos One. 8: e56302. PMID 23437112 DOI: 10.1371/Journal.Pone.0056302  0.589
2013 Wan Q, Kozhaya L, Imberg K, Mercer F, Zhong S, Krogsgaard M, Unutmaz D. Correction: Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors Plos One. 8. DOI: 10.1371/annotation/cbc71d72-f1a2-45de-9d4a-cb0c8dc076b5  0.472
2012 Chandra S, Ding Y, Ma MW, Bannan M, Darvishian F, Berman RS, Shapiro R, Krogsgaard M, Osman I, Pavlick AC. TILs in metastatic melanoma tumors: A biomarker for immunotherapy? Journal of Clinical Oncology. 30: 8589-8589. DOI: 10.1200/Jco.2012.30.15_Suppl.8589  0.316
2012 Park J, Zhong S, Krogsgaard M, Mazumder A. MAGE-A3 Specific T-Cell Receptor Adoptive Cell Transfer of Multiple Myeloma Blood. 120: 1843-1843. DOI: 10.1182/Blood.V120.21.1843.1843  0.465
2011 Krogsgaard M, Ma MW, Friedman EB, Vega-Saenz de Miera E, Darvishian F, Perez-Garcia A, Berman RS, Shapiro RL, Christos PJ, Osman I, Pavlick AC. An analysis of altered melanoma matrix metalloproteinase-23 (MMP-23) expression and response to immune biologic therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 8541. PMID 28021075 DOI: 10.1200/Jco.2011.29.15_Suppl.8541  0.437
2010 Zhong S, Malecek K, Perez-Garcia A, Krogsgaard M. Retroviral transduction of T-cell receptors in mouse T-cells. Journal of Visualized Experiments : Jove. PMID 21048669 DOI: 10.3791/2307  0.802
2010 Corse E, Gottschalk RA, Krogsgaard M, Allison JP. Attenuated T cell responses to a high-potency ligand in vivo. Plos Biology. 8. PMID 20856903 DOI: 10.1371/Journal.Pbio.1000481  0.595
2010 Juang J, Ebert PJ, Feng D, Garcia KC, Krogsgaard M, Davis MM. Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection. The Journal of Experimental Medicine. 207: 1223-34. PMID 20457759 DOI: 10.1084/Jem.20092170  0.365
2009 Call MJ, Xing X, Cuny GD, Seth NP, Altmann DM, Fugger L, Krogsgaard M, Stein RL, Wucherpfennig KW. In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange. Journal of Immunology (Baltimore, Md. : 1950). 182: 6342-52. PMID 19414787 DOI: 10.4049/Jimmunol.0803464  0.306
2007 Krogsgaard M, Juang J, Davis MM. A role for "self" in T-cell activation. Seminars in Immunology. 19: 236-44. PMID 17548210 DOI: 10.1016/J.Smim.2007.04.003  0.563
2007 Davis MM, Krogsgaard M, Huse M, Huppa J, Lillemeier BF, Li QJ. T cells as a self-referential, sensory organ. Annual Review of Immunology. 25: 681-95. PMID 17291190 DOI: 10.1146/Annurev.Immunol.24.021605.090600  0.545
2006 Qi S, Krogsgaard M, Davis MM, Chakraborty AK. Molecular flexibility can influence the stimulatory ability of receptor-ligand interactions at cell-cell junctions. Proceedings of the National Academy of Sciences of the United States of America. 103: 4416-21. PMID 16537380 DOI: 10.1073/Pnas.0510991103  0.454
2005 Maynard J, Adams EJ, Krogsgaard M, Petersson K, Liu CW, Garcia KC. High-level bacterial secretion of single-chain αβ T-cell receptors Journal of Immunological Methods. 306: 51-67. PMID 16198365 DOI: 10.1016/J.Jim.2005.07.022  0.346
2005 Krogsgaard M, Li QJ, Sumen C, Huppa JB, Huse M, Davis MM. Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity. Nature. 434: 238-43. PMID 15724150 DOI: 10.1038/Nature03391  0.483
2005 Krogsgaard M, Davis MM. How T cells 'see' antigen. Nature Immunology. 6: 239-45. PMID 15716973 DOI: 10.1038/Ni1173  0.516
2004 Ranheim EA, Tarbell KV, Krogsgaard M, Mallet-Designe V, Teyton L, McDevitt HO, Weissman IL. Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene. Autoimmunity. 37: 555-67. PMID 15763918 DOI: 10.1080/08916930400020545  0.309
2003 Krogsgaard M, Huppa JB, Purbhoo MA, Davis MM. Linking molecular and cellular events in T-cell activation and synapse formation. Seminars in Immunology. 15: 307-15. PMID 15001169 DOI: 10.1016/J.Smim.2003.09.002  0.447
2003 Krogsgaard M, Prado N, Adams EJ, He XL, Chow DC, Wilson DB, Garcia KC, Davis MM. Evidence that Structural Rearrangements and/or Flexibility during TCR Binding Can Contribute to T Cell Activation Molecular Cell. 12: 1367-1378. PMID 14690592 DOI: 10.1016/S1097-2765(03)00474-X  0.38
2003 Davis MM, Krogsgaard M, Huppa JB, Sumen C, Purbhoo MA, Irvine DJ, Wu LC, Ehrlich L. Dynamics of cell surface molecules during T cell recognition. Annual Review of Biochemistry. 72: 717-42. PMID 14527326 DOI: 10.1146/Annurev.Biochem.72.121801.161625  0.483
2003 Anikeeva N, Lebedeva T, Krogsgaard M, Tetin SY, Martinez-Hackert E, Kalams SA, Davis MM, Sykulev Y. Distinct molecular mechanisms account for the specificity of two different T-cell receptors. Biochemistry. 42: 4709-16. PMID 12705834 DOI: 10.1021/BI026864+  0.312
2002 Irvine DJ, Purbhoo MA, Krogsgaard M, Davis MM. Direct observation of ligand recognition by T cells. Nature. 419: 845-9. PMID 12397360 DOI: 10.1038/Nature01076  0.489
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