☰

Kilannin Krysiak, Ph.D. - Publications

Affiliations: 
2002-2006 Molecular and Cellular Biology University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2006-2008 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2008- Genetics Washington University School of Medicine, St. Louis, MO, United States 
Tree Info Similar researchers PubMed Report error

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wagner AH, Walsh B, Mayfield G, Tamborero D, Sonkin D, Krysiak K, Deu-Pons J, Duren RP, Gao J, McMurry J, Patterson S, Del Vecchio Fitz C, Pitel BA, Sezerman OU, Ellrott K, et al. A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer. Nature Genetics. PMID 32246132 DOI: 10.1038/S41588-020-0603-8  0.376
2020 Kanagal-Shamanna R, Rao S, Terraf P, Raca G, Saliba J, Danos A, Mani C, Williams H, Jiang N, Vavra KC, Zhang L, Shi Z, Li P, Li Y, Ouseph MM, ... ... Krysiak K, et al. Expert Curation of Somatic Variants in Hematological Malignancies By the Clingen Somatic Hematological Cancer Taskforce (ClinGen HCT) Blood. 136: 23-23. DOI: 10.1182/BLOOD-2020-143028  0.306
2020 Rao S, Ritter D, Danos A, Raca G, Roy A, Krysiak K, Lin W, Barnell E, McCoy M, Pitel B, Sonkin D, Wang J, Hosseini SA, Selvarajah S, King I, et al. 46. ClinGen somatic cancer working group: Enhancing standardized interpretation of cancer genetic data for clinical use Cancer Genetics. 244: 17-18. DOI: 10.1016/J.Cancergen.2020.04.050  0.343
2020 Lin W, Roy A, Church A, Rao S, Ritter D, Danos A, Krysiak K, Corson L, Fisher K, Williams H, Hiemenz M, Janeway K, Ji J, Kesserwan C, Laetsch T, et al. 30. Curation of genetic variants in childhood cancers within the Clinical Genome Resource (ClinGen) Cancer Genetics. 244: 11-12. DOI: 10.1016/J.Cancergen.2020.04.034  0.353
2020 Danos A, Krysiak K, Saliba J, Guerra J, Wagner A, McMichael J, Kiwala S, Coffman A, Barnell E, Spies N, Sheta L, Pema S, Kujan L, Clark K, Griffith M, et al. 9. Expansion of the CIViC data model for functional annotation of cancer variants Cancer Genetics. 244: 4. DOI: 10.1016/J.Cancergen.2020.04.013  0.328
2019 Lever J, Jones MR, Danos AM, Krysiak K, Bonakdar M, Grewal JK, Culibrk L, Griffith OL, Griffith M, Jones SJM. Text-mining clinically relevant cancer biomarkers for curation into the CIViC database. Genome Medicine. 11: 78. PMID 31796060 DOI: 10.1186/S13073-019-0686-Y  0.372
2019 Danos AM, Krysiak K, Barnell EK, Coffman AC, McMichael JF, Kiwala S, Spies NC, Sheta LM, Pema SP, Kujan L, Clark KA, Wollam AZ, Rao S, Ritter DI, Sonkin D, et al. Standard operating procedure for curation and clinical interpretation of variants in cancer. Genome Medicine. 11: 76. PMID 31779674 DOI: 10.1186/S13073-019-0687-X  0.368
2019 Campbell KM, O'Leary KA, Rugowski DE, Mulligan WA, Barnell EK, Skidmore ZL, Krysiak K, Griffith M, Schuler LA, Griffith OL. A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation. Cell Reports. 28: 1526-1537.e4. PMID 31390566 DOI: 10.1016/J.Celrep.2019.06.098  0.367
2019 Griffith OL, Krysiak K, Danos A, Barnell E, Spies N, Ainscough B, Kujan L, Clark K, Pema S, Sheta L, Coffman A, Kiwala S, McMichael J, Wagner A, Griffith M. Solving The Interpretation Bottleneck for Cancer Precision Medicine Pathology. 51: S34. DOI: 10.1016/J.Pathol.2018.12.078  0.304
2019 Raca G, Rao S, Ritter D, Danos A, Krysiak K, Church AJ, Corson L, Fisher K, Hiemenz M, Janeway KA, Ji J, Kesserwan CA, Laetsch TW, Parsons DW, Schmidt R, et al. 34. Curation of variants associated with pediatric tumors within the Clinical Genome Resource (ClinGen) Cancer Genetics and Cytogenetics. DOI: 10.1016/J.Cancergen.2019.04.040  0.323
2019 Krysiak K, Danos A, Wagner A, McMichael J, Kiwala S, Coffman A, Spies N, Kujan L, Barnell E, Sheta L, Pema S, Clark K, Feng Y, Ainscough B, Skidmore Z, et al. 33. Aggregating evidence to determine the clinical significance of cancer variants in the CIViC knowledgebase Cancer Genetics and Cytogenetics. DOI: 10.1016/J.Cancergen.2019.04.039  0.345
2019 Gomez F, Skidmore Z, Schmidt A, Rodrigues-Martins F, Krysiak K, Ramirez C, Mosior M, Duncavage E, Triska G, Trani L, Bartlett N, Cashen A, Mehta-Shah N, Kahl B, Kreisel F, et al. 23. Ultra-deep sequencing of classical Hodgkin lymphoma (cHL) reveals novel somatic mutations and exemplifies the utility of deep sequencing in the characterization of rare malignant cells Cancer Genetics and Cytogenetics. DOI: 10.1016/J.Cancergen.2019.04.029  0.351
2018 Griffith OL, Spies NC, Anurag M, Griffith M, Luo J, Tu D, Yeo B, Kunisaki J, Miller CA, Krysiak K, Hundal J, Ainscough BJ, Skidmore ZL, Campbell K, Kumar R, et al. Author Correction: The prognostic effects of somatic mutations in ER-positive breast cancer. Nature Communications. 9: 4850. PMID 30429476 DOI: 10.1038/S41467-018-07407-3  0.31
2018 Danos AM, Ritter DI, Wagner AH, Krysiak K, Sonkin D, Micheel C, McCoy M, Rao S, Raca G, Boca SM, Roy A, Barnell EK, McMichael JF, Kiwala S, Coffman AC, et al. Adapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community-driven standards. Human Mutation. 39: 1721-1732. PMID 30311370 DOI: 10.1002/Humu.23651  0.385
2018 Barnell EK, Ronning P, Campbell KM, Krysiak K, Ainscough BJ, Sheta LM, Pema SP, Schmidt AD, Richters M, Cotto KC, Danos AM, Ramirez C, Skidmore ZL, Spies NC, Hundal J, et al. Standard operating procedure for somatic variant refinement of sequencing data with paired tumor and normal samples. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 30287923 DOI: 10.1038/S41436-018-0278-Z  0.309
2018 Wagner AH, Devarakonda S, Skidmore ZL, Krysiak K, Ramu A, Trani L, Kunisaki J, Masood A, Waqar SN, Spies NC, Morgensztern D, Waligorski J, Ponce J, Fulton RS, Maggi LB, et al. Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer. Nature Communications. 9: 3787. PMID 30224629 DOI: 10.1038/S41467-018-06162-9  0.358
2018 Griffith OL, Spies NC, Anurag M, Griffith M, Luo J, Tu D, Yeo B, Kunisaki J, Miller CA, Krysiak K, Hundal J, Ainscough BJ, Skidmore ZL, Campbell K, Kumar R, et al. The prognostic effects of somatic mutations in ER-positive breast cancer. Nature Communications. 9: 3476. PMID 30181556 DOI: 10.1038/S41467-018-05914-X  0.382
2018 O'Leary KA, Campbell KM, Rugowski DE, Krysiak K, Mulligan WA, Griffith M, Griffith OL, Schuler LA. Abstract 5104: Prolactin-induced mammary tumors: A preclinical model of luminal B breast cancer which exhibits mutations in the RAS pathway Cancer Research. 78: 5104-5104. DOI: 10.1158/1538-7445.Am2018-5104  0.402
2018 Danos A, Ritter D, Krysiak K, Sonkin D, Micheel C, McCoy M, Rao S, Raca G, Boca S, Roy A, Sidiropoulos N, Aisner D, Leon A, Wagner A, Li XS, et al. 29. Integrating ClinGen somatic cancer variant description standards into crowdsourced curation technology via CIViC database for ClinVar submission Cancer Genetics and Cytogenetics. 47. DOI: 10.1016/J.Cancergen.2018.04.090  0.319
2017 Bartlett NL, Costello BA, LaPlant BR, Ansell SM, Kuruvilla JG, Reeder CB, Thye LS, Anderson DM, Krysiak K, Ramirez C, Qi J, Siegel BA, Griffith M, Griffith OL, Gomez F, et al. Single-Agent Ibrutinib in Relapsed or Refractory Follicular Lymphoma: A Phase 2 Consortium Trial. Blood. PMID 29074501 DOI: 10.1182/Blood-2017-09-804641  0.318
2017 Ma CX, Suman V, Goetz MP, Northfelt DW, Burkard ME, Ademuyiwa F, Naughton MJ, Margenthaler J, Aft R, Gray RJ, Tevaarwerk AJ, Wilke LG, Haddad TC, Moynihan T, Loprenzi C, ... ... Krysiak K, et al. A Phase II trial of neoadjuvant MK2206, an AKT inhibitor, with anastrozole in clinical stage 2 or 3 PIK3CA mutant ER positive and HER2 negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28874413 DOI: 10.1158/1078-0432.Ccr-17-1260  0.31
2017 Whyte MP, Griffith M, Trani L, Mumm S, Gottesman GS, McAlister WH, Krysiak K, Lesurf R, Skidmore ZL, Campbell KM, Rosman IS, Bayliss S, Bijanki VN, Nenninger A, Van Tine BA, et al. Melorheostosis: Exome sequencing of an associated dermatosis implicates postzygotic mosaicism of mutated KRAS. Bone. PMID 28434888 DOI: 10.1016/J.Bone.2017.04.010  0.329
2017 Liu T, Krysiak K, Shirai CL, Kim S, Shao J, Ndonwi M, Walter MJ. Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells. Plos One. 12: e0170470. PMID 28178280 DOI: 10.1371/Journal.Pone.0170470  0.324
2017 Griffith M, Spies NC, Krysiak K, McMichael JF, Coffman AC, Danos AM, Ainscough BJ, Ramirez CA, Rieke DT, Kujan L, Barnell EK, Wagner AH, Skidmore ZL, Wollam A, Liu CJ, et al. CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer. Nature Genetics. 49: 170-174. PMID 28138153 DOI: 10.1038/Ng.3774  0.361
2017 Griffith O, Griffith M, Tamborero D, Wagner A, Krysiak K, Fitz CDV, Chakravarty D, Cerami E, Elemento O, Schultz N, Margolin A, Lopez-Bigas N. Global integration of knowledgebases for clinical interpretation of cancer variants F1000research. 6. DOI: 10.7490/F1000Research.1113918.1  0.355
2017 Gomez F, Krysiak K, Ramirez C, Duncavage EJ, Skidmore Z, Triska G, Trani L, Bartlett NL, Cashen AF, Mehta-Shah N, Kahl BS, Kreisel F, Griffith M, Fehniger TA, Griffith O. Ultra Deep Whole Exome Sequencing of Classical Hodgkin Lymphoma (cHL) Reveals Novel Recurrent Somatic Mutations Blood. 130: 2733-2733. DOI: 10.1182/Blood.V130.Suppl_1.2733.2733  0.342
2017 Griffith OL, Griffith M, Tamborero D, Wagner AH, Krysiak K, Fitz CDV, Chakravarty D, Cerami E, Elemento O, Schultz N, Margolin A, Lopez-Bigas N. Abstract 2608: Global integration of knowledgebases for clinical interpretation of cancer variants Cancer Research. 77: 2608-2608. DOI: 10.1158/1538-7445.Am2017-2608  0.356
2017 Gomez F, Krysiak K, Ramirez C, Bartlett N, Cashen A, Kreisel F, Duncavage E, Griffith M, Fehniger T, Griffith O. Abstract 2448: Deep exome sequencing reveals recurrent somatic mutations in Hodgkin's lymphoma Cancer Research. 77: 2448-2448. DOI: 10.1158/1538-7445.Am2017-2448  0.328
2017 Krysiak K, Ramirez C, Gomez F, Miller CA, Fulton RS, Kreisel F, Cashen AF, Bartlett NL, Ruano A, Hsi ED, Griffith M, Griffith OL, Fehniger TA. Abstract 2444: Recurrent mutations and clinical outcomes in patients with follicular lymphoma Cancer Research. 77: 2444-2444. DOI: 10.1158/1538-7445.Am2017-2444  0.312
2016 Krysiak K, Gomez F, White BS, Matlock M, Miller CA, Trani L, Fronick CC, Fulton RS, Kreisel F, Cashen AF, Carson KR, Berrien-Elliott MM, Bartlett NL, Griffith M, Griffith OL, et al. Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma. Blood. PMID 28064239 DOI: 10.1182/Blood-2016-07-729954  0.377
2016 Griffith OL, Chan SR, Griffith M, Krysiak K, Skidmore ZL, Hundal J, Allen JA, Arthur CD, Runci D, Bugatti M, Miceli AP, Schmidt H, Trani L, Kanchi KL, Miller CA, et al. Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas. Cell Reports. 17: 249-60. PMID 27681435 DOI: 10.1016/J.Celrep.2016.08.076  0.367
2016 Griffith M, Griffith OL, Krysiak K, Skidmore ZL, Christopher MJ, Klco JM, Ramu A, Lamprecht TL, Wagner AH, Campbell KM, Lesurf R, Hundal J, Zhang J, Spies NC, Ainscough BJ, et al. Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B lymphoblastic leukemia. Experimental Hematology. PMID 27181063 DOI: 10.1016/J.Exphem.2016.04.011  0.375
2016 Gomez F, Matlock M, Krysiak K, Lee Y, Duncavage EJ, O'Laughlin M, Griffith M, Fehniger TA, Wartman LD, Griffith OL. Exome Sequencing of Hodgkin's and Non-Hodgkin Composite Lymphomas Identifies Shared Somatic Mutations Indicative of Common Founding Precursors Blood. 128: 5285-5285. DOI: 10.1182/Blood.V128.22.5285.5285  0.353
2016 Krysiak K, Jacoby MA, Skidmore ZL, Danos AM, O'Laughlin M, Duncavage EJ, Walter MJ, Griffith M, Griffith OL, Wartman LD. Deleterious Germline Mutations in Telomere Maintenance Genes Identified in a Subset of Patients with Myelodysplastic Syndrome and Idiopathic Pulmonary Fibrosis Blood. 128: 4306-4306. DOI: 10.1182/Blood.V128.22.4306.4306  0.379
2016 Mardis E, Griffith OL, Szeman RC, Griffith M, Krysiak K, Skidmore Z, Hundal J, Allen JA, Cora A, Miceli AP, Schmidt H, Trani L, Kanchi K, Miller CA, Larson DE, et al. Abstract IA20: Genomics of a STAT1 knockout mouse model of human ER+ breast cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-Ia20  0.386
2016 Krysiak K, Gomez F, White BS, Matlock M, Miller CA, Fulton RS, Kreisel F, Cashen AF, Carson KR, Berrien-Elliott MM, Bartlett NL, Wilson RK, Mardis ER, Griffith M, Griffith OL, et al. Abstract LB-326: Identification of novel recurrent mutations in follicular lymphoma Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-326  0.392
2015 Griffith M, Miller CA, Griffith OL, Krysiak K, Skidmore ZL, Ramu A, Walker JR, Dang HX, Trani L, Larson DE, Demeter RT, Wendl MC, McMichael JF, Austin RE, Magrini V, et al. Optimizing cancer genome sequencing and analysis. Cell Systems. 1: 210-223. PMID 26645048 DOI: 10.7490/F1000Research.1110088.1  0.327
2015 Griffith M, Spies N, Krysiak K, McMichael J, Coffman A, Ainscough B, Bilski R, Eldred J, Larson D, Walker J, Wilson R, Mardis E, Griffith O. CIViC: Crowdsourcing the Clinical Interpretation of Variants in Cancer F1000research. 4. DOI: 10.7490/F1000Research.1110019.1  0.366
2015 Fehniger TA, Krysiak K, White BS, Matlock M, Miller C, Fulton R, Kreisel F, Fronick C, Cook L, Veizer J, Cashen AF, Carson KR, Berrien-Elliott MM, Bartlett NL, Wilson RK, et al. Recurrent Somatic Genomic Alterations in Follicular NHL (FL) Revealed By Exome and Custom-Capture Next Generation Sequencing Blood. 126: 574-574. DOI: 10.1182/Blood.V126.23.574.574  0.37
2015 Griffith M, Griffith OL, Ramu A, Ainscough JB, Krysiak K, Choudhary M, Skidmore Z, Tan B, Ramaswamy G, Tine BV, Ellis MJ, Ley TJ, Wilson RK, Mardis ER. Abstract A1-44: Clinical cancer sequencing and integrated analysis of whole genomes, exomes and transcriptomes Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-44  0.348
2014 Liu T, Krysiak K, Shirai CL, Ndonwi M, Walter MJ. Knockdown of HSPA9 Induces Apoptosis and Increases TP53 Levels in Human CD34+ Hematopoietic Progenitor Cells Blood. 124: 526-526. DOI: 10.1182/Blood.V124.21.526.526  0.306
2012 Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nature Genetics. 44: 53-7. PMID 22158538 DOI: 10.1038/Ng.1031  0.337
2011 Chen TH, Kambal A, Krysiak K, Walshauser MA, Raju G, Tibbitts JF, Walter MJ. Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice. Blood. 117: 1530-9. PMID 21123823 DOI: 10.1182/Blood-2010-06-293167  0.32
2010 Zhang Y, Cao R, Yin F, Lin FY, Wang H, Krysiak K, No JH, Mukkamala D, Houlihan K, Li J, Morita CT, Oldfield E. Lipophilic pyridinium bisphosphonates: potent gammadelta T cell stimulators. Angewandte Chemie (International Ed. in English). 49: 1136-8. PMID 20039246 DOI: 10.1002/Anie.200905933  0.482
2009 Zhang Y, Cao R, Yin F, Hudock MP, Guo RT, Krysiak K, Mukherjee S, Gao YG, Robinson H, Song Y, No JH, Bergan K, Leon A, Cass L, Goddard A, et al. Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. Journal of the American Chemical Society. 131: 5153-62. PMID 19309137 DOI: 10.1021/Ja808285E  0.449
2009 Zhang Y, Cao R, Yin F, Lin F, Wang H, Krysiak K, No J, Mukkamala D, Houlihan K, Li J, Morita C, Oldfield E. Lipophilic Pyridinium Bisphosphonates: Potent γδ T Cell Stimulators Angewandte Chemie. 122: 1154-1156. DOI: 10.1002/ange.200905933  0.343
2008 Song Y, Chan JM, Tovian Z, Secrest A, Nagy E, Krysiak K, Bergan K, Parniak MA, Oldfield E. Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3'-azido, 3'-deoxythymidine: a QSAR investigation. Bioorganic & Medicinal Chemistry. 16: 8959-67. PMID 18789701 DOI: 10.1016/J.Bmc.2008.08.047  0.4
2007 Zhang Y, Hudock MP, Krysiak K, Cao R, Bergan K, Yin F, Leon A, Oldfield E. Activity of sulfonium bisphosphonates on tumor cell lines. Journal of Medicinal Chemistry. 50: 6067-79. PMID 17963374 DOI: 10.1021/Jm700991K  0.434
Show low-probability matches.