Laurence Hurst, Ph.D - Publications

Biology and Biochemistry Bath 
Genetics, Genomics

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Hurst LD, Batada NN. Depletion of somatic mutations in splicing-associated sequences in cancer genomes. Genome Biology. 18: 213. PMID 29115978 DOI: 10.1186/s13059-017-1337-5  0.56
2015 Hurst LD, Ghanbarian AT, Forrest AR, Huminiecki L. The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome. Plos Biology. 13: e1002315. PMID 26685068 DOI: 10.1371/journal.pbio.1002315  1
2015 Yang S, Wang L, Huang J, Zhang X, Yuan Y, Chen JQ, Hurst LD, Tian D. Parent-progeny sequencing indicates higher mutation rates in heterozygotes. Nature. PMID 26176923 DOI: 10.1038/nature14649  1
2015 Wu X, Hurst LD. Why Selection Might Be Stronger When Populations Are Small: Intron Size and Density Predict within and between-Species Usage of Exonic Splice Associated cis-Motifs. Molecular Biology and Evolution. 32: 1847-61. PMID 25771198 DOI: 10.1093/molbev/msv069  1
2015 Ghanbarian AT, Hurst LD. Neighboring Genes Show Correlated Evolution in Gene Expression. Molecular Biology and Evolution. 32: 1748-66. PMID 25743543 DOI: 10.1093/molbev/msv053  1
2015 Liu H, Zhang X, Huang J, Chen JQ, Tian D, Hurst LD, Yang S. Causes and consequences of crossing-over evidenced via a high-resolution recombinational landscape of the honey bee. Genome Biology. 16: 15. PMID 25651211 DOI: 10.1186/s13059-014-0566-0  1
2015 Sealey KL, Harris SR, Fry NK, Hurst LD, Gorringe AR, Parkhill J, Preston A. Genomic Analysis of Isolates From the United Kingdom 2012 Pertussis Outbreak Reveals That Vaccine Antigen Genes Are Unusually Fast Evolving. The Journal of Infectious Diseases. 212: 294-301. PMID 25489002 DOI: 10.1093/infdis/jiu665  1
2014 Wang J, Xie G, Singh M, Ghanbarian AT, Raskó T, Szvetnik A, Cai H, Besser D, Prigione A, Fuchs NV, Schumann GG, Chen W, Lorincz MC, Ivics Z, Hurst LD, et al. Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells. Nature. 516: 405-9. PMID 25317556 DOI: 10.1038/nature13804  1
2014 Jiang C, Mithani A, Belfield EJ, Mott R, Hurst LD, Harberd NP. Environmentally responsive genome-wide accumulation of de novo Arabidopsis thaliana mutations and epimutations. Genome Research. 24: 1821-9. PMID 25314969 DOI: 10.1101/gr.177659.114  1
2014 Schüler A, Ghanbarian AT, Hurst LD. Purifying selection on splice-related motifs, not expression level nor RNA folding, explains nearly all constraint on human lincRNAs. Molecular Biology and Evolution. 31: 3164-83. PMID 25158797 DOI: 10.1093/molbev/msu249  0.6
2014 Yin S, Yang J, Lin B, Deng W, Zhang Y, Yi X, Shi Y, Tao Y, Cai J, Wu CI, Zhao G, Hurst LD, Zhang J, Hu L, Kong X. Exome sequencing identifies frequent mutation of MLL2 in non-small cell lung carcinoma from Chinese patients. Scientific Reports. 4: 6036. PMID 25112956 DOI: 10.1038/srep06036  1
2014 Hurst LD, Sachenkova O, Daub C, Forrest AR, Huminiecki L. A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators. Genome Biology. 15: 413. PMID 25079787 DOI: 10.1186/s13059-014-0413-3  1
2014 Laabei M, Recker M, Rudkin JK, Aldeljawi M, Gulay Z, Sloan TJ, Williams P, Endres JL, Bayles KW, Fey PD, Yajjala VK, Widhelm T, Hawkins E, Lewis K, Parfett S, ... ... Hurst LD, et al. Predicting the virulence of MRSA from its genome sequence. Genome Research. 24: 839-49. PMID 24717264 DOI: 10.1101/gr.165415.113  1
2014 Charneski CA, Hurst LD. Positive charge loading at protein termini is due to membrane protein topology, not a translational ramp. Molecular Biology and Evolution. 31: 70-84. PMID 24077849 DOI: 10.1093/molbev/mst169  1
2013 Cáceres EF, Hurst LD. The evolution, impact and properties of exonic splice enhancers. Genome Biology. 14: R143. PMID 24359918 DOI: 10.1186/gb-2013-14-12-r143  1
2013 Zhang Y, Castillo-Morales A, Jiang M, Zhu Y, Hu L, Urrutia AO, Kong X, Hurst LD. Genes that escape X-inactivation in humans have high intraspecific variability in expression, are associated with mental impairment but are not slow evolving. Molecular Biology and Evolution. 30: 2588-601. PMID 24023392 DOI: 10.1093/molbev/mst148  1
2013 Wu X, Tronholm A, Cáceres EF, Tovar-Corona JM, Chen L, Urrutia AO, Hurst LD. Evidence for deep phylogenetic conservation of exonic splice-related constraints: splice-related skews at exonic ends in the brown alga Ectocarpus are common and resemble those seen in humans. Genome Biology and Evolution. 5: 1731-45. PMID 23902749 DOI: 10.1093/gbe/evt115  1
2013 Maharjan R, Nilsson S, Sung J, Haynes K, Beardmore RE, Hurst LD, Ferenci T, Gudelj I. The form of a trade-off determines the response to competition. Ecology Letters. 16: 1267-76. PMID 23902419 DOI: 10.1111/ele.12159  1
2013 Liu Y, Zhang L, Xu S, Hu L, Hurst LD, Kong X. Identification of two maternal transmission ratio distortion loci in pedigrees of the Framingham heart study. Scientific Reports. 3: 2147. PMID 23828458 DOI: 10.1038/srep02147  1
2013 Hurst LD. Open questions: a logic (or lack thereof) of genome organization. Bmc Biology. 11: 58. PMID 23714162 DOI: 10.1186/1741-7007-11-58  1
2013 Woods S, Coghlan A, Rivers D, Warnecke T, Jeffries SJ, Kwon T, Rogers A, Hurst LD, Ahringer J. Duplication and retention biases of essential and non-essential genes revealed by systematic knockdown analyses. Plos Genetics. 9: e1003330. PMID 23675306 DOI: 10.1371/journal.pgen.1003330  1
2013 Charneski CA, Hurst LD. Positively charged residues are the major determinants of ribosomal velocity. Plos Biology. 11: e1001508. PMID 23554576 DOI: 10.1371/journal.pbio.1001508  1
2012 Yang S, Yuan Y, Wang L, Li J, Wang W, Liu H, Chen JQ, Hurst LD, Tian D. Great majority of recombination events in Arabidopsis are gene conversion events. Proceedings of the National Academy of Sciences of the United States of America. 109: 20992-7. PMID 23213238 DOI: 10.1073/pnas.1211827110  1
2012 Fehér T, Bogos B, Méhi O, Fekete G, Csörgo B, Kovács K, Pósfai G, Papp B, Hurst LD, Pál C. Competition between transposable elements and mutator genes in bacteria. Molecular Biology and Evolution. 29: 3153-9. PMID 22527906 DOI: 10.1093/molbev/mss122  1
2012 He C, Li Z, Chen P, Huang H, Hurst LD, Chen J. Young intragenic miRNAs are less coexpressed with host genes than old ones: implications of miRNA-host gene coevolution. Nucleic Acids Research. 40: 4002-12. PMID 22238379 DOI: 10.1093/nar/gkr1312  1
2012 Webster MT, Hurst LD. Direct and indirect consequences of meiotic recombination: implications for genome evolution. Trends in Genetics : Tig. 28: 101-9. PMID 22154475 DOI: 10.1016/j.tig.2011.11.002  1
2012 Weber CC, Pink CJ, Hurst LD. Late-replicating domains have higher divergence and diversity in Drosophila melanogaster. Molecular Biology and Evolution. 29: 873-82. PMID 22046001 DOI: 10.1093/molbev/msr265  1
2011 Warnecke T, Hurst LD. Error prevention and mitigation as forces in the evolution of genes and genomes. Nature Reviews. Genetics. 12: 875-81. PMID 22094950 DOI: 10.1038/nrg3092  1
2011 Pink CJ, Hurst LD. Late replicating domains are highly recombining in females but have low male recombination rates: implications for isochore evolution. Plos One. 6: e24480. PMID 21949720 DOI: 10.1371/journal.pone.0024480  1
2011 Charneski CA, Honti F, Bryant JM, Hurst LD, Feil EJ. Atypical at skew in Firmicute genomes results from selection and not from mutation. Plos Genetics. 7: e1002283. PMID 21935355 DOI: 10.1371/journal.pgen.1002283  1
2011 Nahorski MS, Reiman A, Lim DH, Nookala RK, Seabra L, Lu X, Fenton J, Boora U, Nordenskjöld M, Latif F, Hurst LD, Maher ER. Birt Hogg-Dubé syndrome-associated FLCN mutations disrupt protein stability. Human Mutation. 32: 921-9. PMID 21538689 DOI: 10.1002/humu.21519  1
2011 Hurst LD. Molecular genetics: The sound of silence. Nature. 471: 582-3. PMID 21455166 DOI: 10.1038/471582a  1
2011 Beardmore RE, Gudelj I, Lipson DA, Hurst LD. Metabolic trade-offs and the maintenance of the fittest and the flattest. Nature. 472: 342-6. PMID 21441905 DOI: 10.1038/nature09905  1
2011 Weber CC, Hurst LD. Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation. Genome Biology. 12: R23. PMID 21414197 DOI: 10.1186/gb-2011-12-3-r23  1
2011 Wang GZ, Lercher MJ, Hurst LD. Transcriptional coupling of neighboring genes and gene expression noise: evidence that gene orientation and noncoding transcripts are modulators of noise. Genome Biology and Evolution. 3: 320-31. PMID 21402863 DOI: 10.1093/gbe/evr025  1
2011 Garfield AS, Cowley M, Smith FM, Moorwood K, Stewart-Cox JE, Gilroy K, Baker S, Xia J, Dalley JW, Hurst LD, Wilkinson LS, Isles AR, Ward A. Distinct physiological and behavioural functions for parental alleles of imprinted Grb10. Nature. 469: 534-8. PMID 21270893 DOI: 10.1038/nature09651  1
2010 Zhang Z, Zhou L, Hu L, Zhu Y, Xu H, Liu Y, Chen X, Yi X, Kong X, Hurst LD. Nonsense-mediated decay targets have multiple sequence-related features that can inhibit translation. Molecular Systems Biology. 6: 442. PMID 21179015 DOI: 10.1038/msb.2010.101  1
2010 Weber CC, Hurst LD. Intronic AT skew is a defendable proxy for germline transcription but does not predict crossing-over or protein evolution rates in Drosophila melanogaster. Journal of Molecular Evolution. 71: 415-26. PMID 20938653 DOI: 10.1007/s00239-010-9395-2  1
2010 MaClean RC, Fuentes-Hernandez A, Greig D, Hurst LD, Gudelj I. A mixture of "cheats" and "co-operators" can enable maximal group benefit. Plos Biology. 8. PMID 20856906 DOI: 10.1371/journal.pbio.1000486  1
2010 Warnecke T, Huang Y, Przytycka TM, Hurst LD. Unique cost dynamics elucidate the role of frameshifting errors in promoting translational robustness. Genome Biology and Evolution. 2: 636-45. PMID 20688751 DOI: 10.1093/gbe/evq049  1
2010 McDonald LA, Gerrelli D, Fok Y, Hurst LD, Tickle C. Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos. Journal of Anatomy. 216: 683-91. PMID 20408909 DOI: 10.1111/j.1469-7580.2010.01233.x  1
2010 Warnecke T, Hurst LD. GroEL dependency affects codon usage--support for a critical role of misfolding in gene evolution. Molecular Systems Biology. 6: 340. PMID 20087338 DOI: 10.1038/msb.2009.94  1
2010 Pink CJ, Hurst LD. Timing of replication is a determinant of neutral substitution rates but does not explain slow Y chromosome evolution in rodents. Molecular Biology and Evolution. 27: 1077-86. PMID 20026481 DOI: 10.1093/molbev/msp314  1
2010 Charalambous M, Cowley M, Geoghegan F, Smith FM, Radford EJ, Marlow BP, Graham CF, Hurst LD, Ward A. Maternally-inherited Grb10 reduces placental size and efficiency. Developmental Biology. 337: 1-8. PMID 19833122 DOI: 10.1016/j.ydbio.2009.10.011  1
2009 Weber CC, Hurst LD. Protein rates of evolution are predicted by double-strand break events, independent of crossing-over rates. Genome Biology and Evolution. 1: 340-9. PMID 20333203 DOI: 10.1093/gbe/evp033  0.96
2009 Pink CJ, Swaminathan SK, Dunham I, Rogers J, Ward A, Hurst LD. Evidence that replication-associated mutation alone does not explain between-chromosome differences in substitution rates. Genome Biology and Evolution. 1: 13-22. PMID 20333173 DOI: 10.1093/gbe/evp001  0.32
2009 Necsulea A, Sémon M, Duret L, Hurst LD. Monoallelic expression and tissue specificity are associated with high crossover rates. Trends in Genetics : Tig. 25: 519-22. PMID 19850368 DOI: 10.1016/j.tig.2009.10.001  1
2009 Warnecke T, Wang GZ, Lercher MJ, Hurst LD. Does negative auto-regulation increase gene duplicability? Bmc Evolutionary Biology. 9: 193. PMID 19664220 DOI: 10.1186/1471-2148-9-193  1
2009 Warnecke T, Weber CC, Hurst LD. Why there is more to protein evolution than protein function: splicing, nucleosomes and dual-coding sequence. Biochemical Society Transactions. 37: 756-61. PMID 19614589 DOI: 10.1042/BST0370756  1
2009 Yin S, Wang P, Deng W, Zheng H, Hu L, Hurst LD, Kong X. Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals. Genome Biology. 10: R74. PMID 19594925 DOI: 10.1186/gb-2009-10-7-r74  1
2009 Kovács K, Hurst LD, Papp B. Stochasticity in protein levels drives colinearity of gene order in metabolic operons of Escherichia coli. Plos Biology. 7: e1000115. PMID 19492041 DOI: 10.1371/journal.pbio.1000115  1
2009 Chamary JV, Hurst LD. The price of silent mutations. Scientific American. 300: 46-53. PMID 19485088 DOI: 10.1038/scientificamerican0609-46  1
2009 Zhang Z, Xin D, Wang P, Zhou L, Hu L, Kong X, Hurst LD. Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay. Bmc Biology. 7: 23. PMID 19442261 DOI: 10.1186/1741-7007-7-23  1
2009 Hurst LD. Evolutionary genomics and the reach of selection. Journal of Biology. 8: 12. PMID 19291255 DOI: 10.1186/jbiol113  1
2009 Hurst LD. Evolutionary genomics: A positive becomes a negative. Nature. 457: 543-4. PMID 19177117 DOI: 10.1038/457543a  1
2009 Hurst LD. Fundamental concepts in genetics: genetics and the understanding of selection. Nature Reviews. Genetics. 10: 83-93. PMID 19119264 DOI: 10.1038/nrg2506  1
2009 Chamary JV, Hurst LD. Clarifications Scientific American. 301: 12.  1
2008 Wang P, Yin S, Zhang Z, Xin D, Hu L, Kong X, Hurst LD. Evidence for common short natural trans sense-antisense pairing between transcripts from protein coding genes. Genome Biology. 9: R169. PMID 19055728 DOI: 10.1186/gb-2008-9-12-r169  1
2008 Warnecke T, Batada NN, Hurst LD. The impact of the nucleosome code on protein-coding sequence evolution in yeast. Plos Genetics. 4: e1000250. PMID 18989456 DOI: 10.1371/journal.pgen.1000250  1
2008 Forde SE, Beardmore RE, Gudelj I, Arkin SS, Thompson JN, Hurst LD. Understanding the limits to generalizability of experimental evolutionary models. Nature. 455: 220-3. PMID 18784724 DOI: 10.1038/nature07152  1
2008 Lopes SS, Yang X, Müller J, Carney TJ, McAdow AR, Rauch GJ, Jacoby AS, Hurst LD, Delfino-Machín M, Haffter P, Geisler R, Johnson SL, Ward A, Kelsh RN. Leukocyte tyrosine kinase functions in pigment cell development. Plos Genetics. 4: e1000026. PMID 18369445 DOI: 10.1371/journal.pgen.1000026  1
2008 Reuter M, Engelstädter J, Fontanillas P, Hurst LD. A test of the null model for 5' UTR evolution based on GC content. Molecular Biology and Evolution. 25: 801-4. PMID 18296414 DOI: 10.1093/molbev/msn044  1
2008 Warnecke T, Parmley JL, Hurst LD. Finding exonic islands in a sea of non-coding sequence: splicing related constraints on protein composition and evolution are common in intron-rich genomes. Genome Biology. 9: R29. PMID 18257921 DOI: 10.1186/gb-2008-9-2-r29  1
2008 Urrutia AO, Ocaña LB, Hurst LD. Do Alu repeats drive the evolution of the primate transcriptome? Genome Biology. 9: R25. PMID 18241332 DOI: 10.1186/gb-2008-9-2-r25  1
2008 Champion de Crespigny FE, Hurst LD, Wedell N. Do Wolbachia-associated incompatibilities promote polyandry? Evolution; International Journal of Organic Evolution. 62: 107-22. PMID 18067571 DOI: 10.1111/j.1558-5646.2007.00274.x  1
2007 Poyatos JF, Hurst LD. The determinants of gene order conservation in yeasts. Genome Biology. 8: R233. PMID 17983469 DOI: 10.1186/gb-2007-8-11-r233  1
2007 Warnecke T, Hurst LD. Evidence for a trade-off between translational efficiency and splicing regulation in determining synonymous codon usage in Drosophila melanogaster. Molecular Biology and Evolution. 24: 2755-62. PMID 17905999 DOI: 10.1093/molbev/msm210  1
2007 Batada NN, Urrutia AO, Hurst LD. Chromatin remodelling is a major source of coexpression of linked genes in yeast. Trends in Genetics : Tig. 23: 480-4. PMID 17822800 DOI: 10.1016/j.tig.2007.08.003  1
2007 Batada NN, Hurst LD. Evolution of chromosome organization driven by selection for reduced gene expression noise. Nature Genetics. 39: 945-9. PMID 17660811 DOI: 10.1038/ng2071  1
2007 Batada NN, Reguly T, Breitkreutz A, Boucher L, Breitkreutz BJ, Hurst LD, Tyers M. Still stratus not altocumulus: further evidence against the date/party hub distinction. Plos Biology. 5: e154. PMID 17564494 DOI: 10.1371/journal.pbio.0050154  1
2007 Parmley JL, Hurst LD. How common are intragene windows with KA > KS owing to purifying selection on synonymous mutations? Journal of Molecular Evolution. 64: 646-55. PMID 17557167 DOI: 10.1007/s00239-006-0207-7  1
2007 Parmley JL, Hurst LD. Exonic splicing regulatory elements skew synonymous codon usage near intron-exon boundaries in mammals. Molecular Biology and Evolution. 24: 1600-3. PMID 17525472 DOI: 10.1093/molbev/msm104  1
2007 Parmley JL, Hurst LD. How do synonymous mutations affect fitness? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 29: 515-9. PMID 17508390 DOI: 10.1002/bies.20592  1
2007 Parmley JL, Urrutia AO, Potrzebowski L, Kaessmann H, Hurst LD. Splicing and the evolution of proteins in mammals. Plos Biology. 5: e14. PMID 17298171 DOI: 10.1371/journal.pbio.0050014  1
2006 Simões B, Conceição N, Viegas CS, Pinto JP, Gavaia PJ, Hurst LD, Kelsh RN, Cancela ML. Identification of a promoter element within the zebrafish colXalpha1 gene responsive to runx2 isoforms Osf2/Cbfa1 and til-1 but not to pebp2alphaA2. Calcified Tissue International. 79: 230-44. PMID 17033725 DOI: 10.1007/s00223-006-0111-6  1
2006 Batada NN, Reguly T, Breitkreutz A, Boucher L, Breitkreutz BJ, Hurst LD, Tyers M. Stratus not altocumulus: a new view of the yeast protein interaction network. Plos Biology. 4: e317. PMID 16984220 DOI: 10.1371/journal.pbio.0040317  1
2006 Hurst LD, Feil EJ, Rocha EP. Protein evolution: causes of trends in amino-acid gain and loss. Nature. 442: E11-2; discussion E1. PMID 16929253 DOI: 10.1038/nature05137  1
2006 Batada NN, Hurst LD, Tyers M. Evolutionary and physiological importance of hub proteins. Plos Computational Biology. 2: e88. PMID 16839197 DOI: 10.1371/journal.pcbi.0020088  1
2006 Poyatos JF, Hurst LD. Is optimal gene order impossible? Trends in Genetics : Tig. 22: 420-3. PMID 16806566 DOI: 10.1016/j.tig.2006.06.003  1
2006 Hurst LD. Preliminary assessment of the impact of microRNA-mediated regulation on coding sequence evolution in mammals. Journal of Molecular Evolution. 63: 174-82. PMID 16786435 DOI: 10.1007/s00239-005-0273-2  1
2006 Sun M, Hurst LD, Carmichael GG, Chen J. Evidence for variation in abundance of antisense transcripts between multicellular animals but no relationship between antisense transcriptionand organismic complexity. Genome Research. 16: 922-33. PMID 16769979 DOI: 10.1101/gr.5210006  1
2006 Lercher MJ, Hurst LD. Co-expressed yeast genes cluster over a long range but are not regularly spaced. Journal of Molecular Biology. 359: 825-31. PMID 16631793 DOI: 10.1016/j.jmb.2006.03.051  1
2006 Pál C, Papp B, Lercher MJ, Csermely P, Oliver SG, Hurst LD. Chance and necessity in the evolution of minimal metabolic networks. Nature. 440: 667-70. PMID 16572170 DOI: 10.1038/nature04568  1
2006 Chamary JV, Parmley JL, Hurst LD. Hearing silence: non-neutral evolution at synonymous sites in mammals. Nature Reviews. Genetics. 7: 98-108. PMID 16418745 DOI: 10.1038/nrg1770  1
2006 Rocha EP, Smith JM, Hurst LD, Holden MT, Cooper JE, Smith NH, Feil EJ. Comparisons of dN/dS are time dependent for closely related bacterial genomes. Journal of Theoretical Biology. 239: 226-35. PMID 16239014 DOI: 10.1016/j.jtbi.2005.08.037  1
2006 Parmley JL, Chamary JV, Hurst LD. Evidence for purifying selection against synonymous mutations in mammalian exonic splicing enhancers. Molecular Biology and Evolution. 23: 301-9. PMID 16221894 DOI: 10.1093/molbev/msj035  1
2005 Hurst LD, Lercher MJ. Unusual linkage patterns of ligands and their cognate receptors indicate a novel reason for non-random gene order in the human genome. Bmc Evolutionary Biology. 5: 62. PMID 16277660 DOI: 10.1186/1471-2148-5-62  1
2005 Hurst LD, Duret L. Bioinformatics with a French accent. Genome Biology. 6: 349. PMID 16207367 DOI: 10.1186/gb-2005-6-10-349  1
2005 Sun M, Hurst LD, Carmichael GG, Chen J. Evidence for a preferential targeting of 3'-UTRs by cis-encoded natural antisense transcripts. Nucleic Acids Research. 33: 5533-43. PMID 16204454 DOI: 10.1093/nar/gki852  1
2005 Chamary JV, Hurst LD. Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals. Genome Biology. 6: R75. PMID 16168082 DOI: 10.1186/gb-2005-6-9-r75  1
2005 Chen J, Sun M, Rowley JD, Hurst LD. The small introns of antisense genes are better explained by selection for rapid transcription than by "genomic design". Genetics. 171: 2151-5. PMID 16143605 DOI: 10.1534/genetics.105.048066  1
2005 Seoighe C, Gehring C, Hurst LD. Gametophytic selection in Arabidopsis thaliana supports the selective model of intron length reduction. Plos Genetics. 1: e13. PMID 16110339 DOI: 10.1371/journal.pgen.0010013  1
2005 Pinto JP, Conceição NM, Viegas CS, Leite RB, Hurst LD, Kelsh RN, Cancela ML. Identification of a new pebp2alphaA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1440-53. PMID 16007341 DOI: 10.1359/JBMR.050318  1
2005 Chen J, Sun M, Hurst LD, Carmichael GG, Rowley JD. Genome-wide analysis of coordinate expression and evolution of human cis-encoded sense-antisense transcripts. Trends in Genetics : Tig. 21: 326-9. PMID 15922830 DOI: 10.1016/j.tig.2005.04.006  1
2005 Chamary JV, Hurst LD. Biased codon usage near intron-exon junctions: selection on splicing enhancers, splice-site recognition or something else? Trends in Genetics : Tig. 21: 256-9. PMID 15851058 DOI: 10.1016/j.tig.2005.03.001  1
2005 Chen J, Sun M, Hurst LD, Carmichael GG, Rowley JD. Human antisense genes have unusually short introns: evidence for selection for rapid transcription. Trends in Genetics : Tig. 21: 203-7. PMID 15797613 DOI: 10.1016/j.tig.2005.02.003  1
2005 Gissen P, Johnson CA, Gentle D, Hurst LD, Doherty AJ, O'Kane CJ, Kelly DA, Maher ER. Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights. Human Molecular Genetics. 14: 1261-70. PMID 15790593 DOI: 10.1093/hmg/ddi137  1
2005 Hurst LD, Pál C. Dissecting dispensability. Nature Genetics. 37: 214-5. PMID 15731753 DOI: 10.1038/ng0305-214  1
2005 Ruvinsky A, Eskesen ST, Eskesen FN, Hurst LD. Can codon usage bias explain intron phase distributions and exon symmetry? Journal of Molecular Evolution. 60: 99-104. PMID 15696372 DOI: 10.1007/s00239-004-0032-9  1
2004 Poyatos JF, Hurst LD. How biologically relevant are interaction-based modules in protein networks? Genome Biology. 5: R93. PMID 15535869 DOI: 10.1186/gb-2004-5-11-r93  1
2004 Holden MT, Feil EJ, Lindsay JA, Peacock SJ, Day NP, Enright MC, Foster TJ, Moore CE, Hurst L, Atkin R, Barron A, Bason N, Bentley SD, Chillingworth C, Chillingworth T, et al. Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proceedings of the National Academy of Sciences of the United States of America. 101: 9786-91. PMID 15213324 DOI: 10.1073/pnas.0402521101  1
2004 Lercher MJ, Chamary JV, Hurst LD. Genomic regionality in rates of evolution is not explained by clustering of genes of comparable expression profile. Genome Research. 14: 1002-13. PMID 15173108 DOI: 10.1101/gr.1597404  1
2004 Hurst LD, Pál C, Lercher MJ. The evolutionary dynamics of eukaryotic gene order. Nature Reviews. Genetics. 5: 299-310. PMID 15131653 DOI: 10.1038/nrg1319  1
2004 Chamary JV, Hurst LD. Similar rates but different modes of sequence evolution in introns and at exonic silent sites in rodents: evidence for selectively driven codon usage. Molecular Biology and Evolution. 21: 1014-23. PMID 15014158 DOI: 10.1093/molbev/msh087  1
2003 Lercher MJ, Hurst LD. Imprinted chromosomal regions of the human genome have unusually high recombination rates. Genetics. 165: 1629-32. PMID 14733198  1
2003 Lercher MJ, Urrutia AO, Pavlícek A, Hurst LD. A unification of mosaic structures in the human genome. Human Molecular Genetics. 12: 2411-5. PMID 12915446 DOI: 10.1093/hmg/ddg251  1
2003 Lercher MJ, Urrutia AO, Hurst LD. Evidence that the human X chromosome is enriched for male-specific but not female-specific genes. Molecular Biology and Evolution. 20: 1113-6. PMID 12777530 DOI: 10.1093/molbev/msg131  1
1993 Hurst LD, Grafen A. Unusual mutational mechanisms and evolution. Science (New York, N.Y.). 260: 1959; author reply 1. PMID 8316838  1
1992 Hurst LD, Hamilton WD, Ladle RJ. Covert sex. Trends in Ecology & Evolution. 7: 144-5. PMID 21235987 DOI: 10.1016/0169-5347(92)90205-P  1
1990 Hurst L, Grafen A. Sex and flagellation. Trends in Ecology & Evolution. 5: 419-22. PMID 21232406 DOI: 10.1016/0169-5347(90)90029-D  1
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