Year |
Citation |
Score |
2022 |
Cabera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H, Haynes KA, Morsut L, Chen YY, et al. The sound of silence: Transgene silencing in mammalian cell engineering. Cell Systems. 13: 950-973. PMID 36549273 DOI: 10.1016/j.cels.2022.11.005 |
0.547 |
|
2020 |
Li JH, Chen YY. A Fresh Approach to Targeting Aging Cells: CAR-T Cells Enhance Senolytic Specificity. Cell Stem Cell. 27: 192-194. PMID 32763179 DOI: 10.1016/J.Stem.2020.07.010 |
0.358 |
|
2020 |
Jayaraman J, Mellody MP, Hou AJ, Desai RP, Fung AW, Pham AHT, Chen YY, Zhao W. CAR-T design: Elements and their synergistic function. Ebiomedicine. 58: 102931. PMID 32739874 DOI: 10.1016/J.Ebiom.2020.102931 |
0.401 |
|
2020 |
Hong M, Clubb JD, Chen YY. Engineering CAR-T Cells for Next-Generation Cancer Therapy. Cancer Cell. PMID 32735779 DOI: 10.1016/J.Ccell.2020.07.005 |
0.383 |
|
2020 |
Zah E, Nam E, Bhuvan V, Tran U, Ji BY, Gosliner SB, Wang X, Brown CE, Chen YY. Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma. Nature Communications. 11: 2283. PMID 32385241 DOI: 10.1038/S41467-020-16160-5 |
0.378 |
|
2020 |
Chang ZL, Hou AJ, Chen YY. Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands. Nature Protocols. PMID 32103205 DOI: 10.1038/S41596-020-0294-8 |
0.389 |
|
2019 |
Chen YY, Van Deventer JA. Editorial overview: Pharmaceutical biotechnology: new frontiers in protein, gene, and cell therapies. Current Opinion in Biotechnology. PMID 31690473 DOI: 10.1016/J.Copbio.2019.09.022 |
0.306 |
|
2019 |
Chen LC, Chen YY. Outsmarting and outmuscling cancer cells with synthetic and systems immunology. Current Opinion in Biotechnology. 60: 111-118. PMID 30822698 DOI: 10.1016/J.Copbio.2019.01.016 |
0.387 |
|
2018 |
Chen YY. Increasing T Cell Versatility with SUPRA CARs. Cell. 173: 1316-1317. PMID 29856949 DOI: 10.1016/J.Cell.2018.05.030 |
0.356 |
|
2018 |
Chang ZL, Lorenzini MH, Chen X, Tran U, Bangayan NJ, Chen YY. Rewiring T-cell responses to soluble factors with chimeric antigen receptors. Nature Chemical Biology. PMID 29377003 DOI: 10.1038/Nchembio.2565 |
0.354 |
|
2018 |
Chang ZL, Lorenzini MH, Chen YY. Abstract IA08: Engineering T cells to resist and convert immunosuppressive tumor microenvironments Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Ia08 |
0.325 |
|
2017 |
Wong RS, Chen YY, Smolke CD. Regulation of T cell proliferation with drug-responsive microRNA switches. Nucleic Acids Research. PMID 29244152 DOI: 10.1093/Nar/Gkx1228 |
0.701 |
|
2017 |
Ho P, Chen YY. Mammalian synthetic biology in the age of genome editing and personalized medicine. Current Opinion in Chemical Biology. 40: 57-64. PMID 28628856 DOI: 10.1016/J.Cbpa.2017.06.003 |
0.346 |
|
2017 |
Ho P, Ede C, Chen YY. Modularly Constructed Synthetic Granzyme B Molecule Enables Interrogation of Intracellular Proteases for Targeted Cytotoxicity. Acs Synthetic Biology. PMID 28510446 DOI: 10.1021/Acssynbio.6B00392 |
0.395 |
|
2017 |
Chang ZL, Chen YY. CARs: Synthetic Immunoreceptors for Cancer Therapy and Beyond. Trends in Molecular Medicine. PMID 28416139 DOI: 10.1016/J.Molmed.2017.03.002 |
0.391 |
|
2017 |
Zah E, Lin M, Jensen MC, Silva-Benedict A, Chen YY. Abstract IA12: Combating antigen escape with CD19/CD20 bispecific CAR-T cell therapy Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-Ia12 |
0.32 |
|
2016 |
Zah E, Lin MY, Silva-Benedict A, Jensen MC, Chen YY. T cells expressing CD19/CD20 bi-specific chimeric antigen receptors prevent antigen escape by malignant B cells. Cancer Immunology Research. PMID 27059623 DOI: 10.1158/2326-6066.Cir-15-0231 |
0.323 |
|
2016 |
Ede C, Chen X, Lin MY, Chen YY. Quantitative Analyses of Core Promoters Enable Precise Engineering of Regulated Gene Expression in Mammalian Cells. Acs Synthetic Biology. PMID 26883397 DOI: 10.1021/Acssynbio.5B00266 |
0.36 |
|
2016 |
Chang ZL, Silver PA, Chen YY. Abstract B022: Functional bifurcation in T cells expressing chimeric antigen receptors Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B022 |
0.368 |
|
2015 |
Liang JH, Gao R, Xia Y, Gale RP, Chen RZ, Yang YQ, Wang L, Qu XY, Qiu HR, Cao L, Hong M, Wang R, Wang Y, Fan L, Chen YY, et al. Prognostic impact of Epstein-Barr Virus (EBV)-DNA copy number at diagnosis in chronic lymphocytic leukemia. Oncotarget. PMID 26539641 DOI: 10.18632/oncotarget.6281 |
0.365 |
|
2015 |
Chen YY. Efficient Gene Editing in Primary Human T Cells. Trends in Immunology. PMID 26440702 DOI: 10.1016/J.It.2015.09.001 |
0.376 |
|
2015 |
Chang ZL, Silver PA, Chen YY. Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors. Journal of Translational Medicine. 13: 161. PMID 25990251 DOI: 10.1186/S12967-015-0519-8 |
0.363 |
|
2013 |
Wei KY, Chen YY, Smolke CD. A yeast-based rapid prototype platform for gene control elements in mammalian cells. Biotechnology and Bioengineering. 110: 1201-10. PMID 23184812 DOI: 10.1002/Bit.24792 |
0.667 |
|
2012 |
Chen YY, Galloway KE, Smolke CD. Synthetic biology: advancing biological frontiers by building synthetic systems. Genome Biology. 13: 240. PMID 22348749 DOI: 10.1186/Gb-2012-13-2-240 |
0.653 |
|
2011 |
Chen YY, Smolke CD. From DNA to targeted therapeutics: bringing synthetic biology to the clinic. Science Translational Medicine. 3: 106ps42. PMID 22030748 DOI: 10.1126/Scitranslmed.3002944 |
0.606 |
|
2011 |
Beisel CL, Chen YY, Culler SJ, Hoff KG, Smolke CD. Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing. Nucleic Acids Research. 39: 2981-94. PMID 21149259 DOI: 10.1093/Nar/Gkq954 |
0.646 |
|
2010 |
Chen YY, Jensen MC, Smolke CD. Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems. Proceedings of the National Academy of Sciences of the United States of America. 107: 8531-6. PMID 20421500 DOI: 10.1073/Pnas.1001721107 |
0.644 |
|
2008 |
Chen YY, Brown CE, Jensen MC, Smolke CD. T cell proliferation control with small molecule-responsive RNA-based regulatory systems Aiche Annual Meeting, Conference Proceedings. |
0.591 |
|
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