Volker H. Haase, M.D. - Publications

Affiliations: 
1996-2001 Whitehead Institute for Biomedical Research (MIT) 
 2001-2008 University of Pennsylvania School of Medicine, Philadelphia, PA, United States 
 2008- Vanderbilt University Medical Center, Nashville, TN, United States 

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Koury MJ, Haase VH. Deregulating iron-erythropoiesis regulation: transferrin receptor 2 as potential target for treating anemia in CKD. Kidney International. 104: 25-28. PMID 37349056 DOI: 10.1016/j.kint.2023.04.017  0.608
2023 Ku E, Del Vecchio L, Eckardt KU, Haase VH, Johansen KL, Nangaku M, Tangri N, Waikar SS, Więcek A, Cheung M, Jadoul M, Winkelmayer WC, Wheeler DC. Novel Anemia Therapies in Chronic Kidney Disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International. PMID 37236424 DOI: 10.1016/j.kint.2023.05.009  0.596
2022 Li J, Haase VH, Hao CM. Updates on Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors in the Treatment of Renal Anemia. Kidney Diseases (Basel, Switzerland). 9: 1-11. PMID 36756084 DOI: 10.1159/000527835  0.649
2022 Song W, Postoak JL, Yang G, Guo X, Pua HH, Bader J, Rathmell JC, Kobayashi H, Haase VH, Leaptrot KL, Schrimpe-Rutledge AC, Sherrod SD, McLean JA, Zhang J, Wu L, et al. Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases. Proceedings of the National Academy of Sciences of the United States of America. 120: e2214874120. PMID 36574710 DOI: 10.1073/pnas.2214874120  0.577
2022 Koury MJ, Agarwal R, Chertow GM, Eckardt KU, Fishbane S, Ganz T, Haase VH, Hanudel MR, Parfrey PS, Pergola PE, Roy-Chaudhury P, Tumlin JA, Anders R, Farag YMK, Luo W, et al. Erythropoietic effects of vadadustat in patients with anemia associated with chronic kidney disease. American Journal of Hematology. PMID 35751858 DOI: 10.1002/ajh.26644  0.568
2022 Clayton DB, Tong CMC, Li B, Taylor AS, De S, Mason MD, Dudley AG, Davidoff O, Kobayashi H, Haase VH. Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction. American Journal of Physiology. Renal Physiology. PMID 35499237 DOI: 10.1152/ajprenal.00344.2021  0.653
2022 Kobayashi H, Davidoff O, Pujari-Palmer S, Drevin M, Haase VH. EPO synthesis induced by HIF-PHD inhibition is dependent on myofibroblast transdifferentiation and colocalizes with non-injured nephron segments in murine kidney fibrosis. Acta Physiologica (Oxford, England). e13826. PMID 35491502 DOI: 10.1111/apha.13826  0.679
2022 Guan N, Kobayashi H, Ishii K, Davidoff O, Sha F, Ikizler TA, Hao CM, Chandel NS, Haase VH. Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency. Kidney International. PMID 35341793 DOI: 10.1016/j.kint.2022.02.030  0.636
2022 Haase VH. The ins and outs of ferric citrate. Kidney International. 101: 668-670. PMID 35314048 DOI: 10.1016/j.kint.2021.12.032  0.576
2021 Boothby MR, Raybuck A, Cho SH, Stengel KR, Haase VH, Hiebert S, Li J. Over-Generalizing About GC (Hypoxia): Pitfalls of Limiting Breadth of Experimental Systems and Analyses in Framing Informatics Conclusions. Frontiers in Immunology. 12: 664249. PMID 34040610 DOI: 10.3389/fimmu.2021.664249  0.555
2021 Burmakin M, Fasching A, Kobayashi H, Urrutia AA, Damdimopoulos A, Palm F, Haase VH. Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation. Acta Physiologica (Oxford, England). e13668. PMID 33900001 DOI: 10.1111/apha.13668  0.68
2021 Babitt JL, Eisenga MF, Haase VH, Kshirsagar AV, Levin A, Locatelli F, Małyszko J, Swinkels DW, Tarng DC, Cheung M, Jadoul M, Winkelmayer WC, Drüeke TB. Controversies in Optimal Anemia Management: Conclusions from a Kidney Disease Improving Global Outcomes (KDIGO) Conference. Kidney International. PMID 33839163 DOI: 10.1016/j.kint.2021.03.020  0.584
2021 Haase VH. Hypoxia-inducible factor-prolyl hydroxylase inhibitors in the treatment of anemia of chronic kidney disease. Kidney International Supplements. 11: 8-25. PMID 33777492 DOI: 10.1016/j.kisu.2020.12.002  0.644
2020 Ishii K, Kobayashi H, Taguchi K, Guan N, Li A, Tong C, Davidoff O, Tran PV, Sharma M, Chandel NS, Kapp ME, Fogo AB, Brooks CR, Haase VH. Kidney epithelial targeted mitochondrial transcription factor A deficiency results in progressive mitochondrial depletion associated with severe cystic disease. Kidney International. PMID 33159962 DOI: 10.1016/j.kint.2020.10.013  0.59
2020 Zou J, Yang J, Zhu X, Zhong J, Elshaer A, Matsusaka T, Pastan I, Haase VH, Yang HC, Fogo AB. Stabilization of Hypoxia-Inducible Factor Ameliorates Glomerular Injury Sensitization after Tubulointerstitial Injury. Kidney International. PMID 33137336 DOI: 10.1016/j.kint.2020.09.031  0.596
2020 Urrutia AA, Guan N, Mesa-Ciller C, Afzal A, Davidoff O, Haase VH. Inactivation of HIF-prolyl 4-hydroxylases 1, 2 and 3 in NG2-expressing cells induces HIF2-mediated neurovascular expansion independent of erythropoietin. Acta Physiologica (Oxford, England). PMID 32846048 DOI: 10.1111/Apha.13547  0.692
2020 Haase VH. Got glycogen? An energy resource in HIF-mediated prevention of ischemic kidney injury. Kidney International. 97: 645-647. PMID 32200856 DOI: 10.1016/J.Kint.2019.11.036  0.703
2019 Sanghani NS, Haase VH. Hypoxia-Inducible Factor Activators in Renal Anemia: Current Clinical Experience. Advances in Chronic Kidney Disease. 26: 253-266. PMID 31477256 DOI: 10.1053/J.Ackd.2019.04.004  0.675
2019 Cho SH, Raybuck AL, Blagih J, Kemboi E, Haase VH, Jones RG, Boothby MR. Hypoxia-inducible factors in CD4 T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30988188 DOI: 10.1073/Pnas.1811702116  0.628
2019 Buell KG, Trumbo SP, Haase VH. Diagnostic Dilemma: A Unilateral Facial Rash with Eye Involvement. The American Journal of Medicine. PMID 30849384 DOI: 10.1016/J.Amjmed.2019.02.007  0.528
2018 Haase VH. ARNT as a Novel Antifibrotic Target in CKD. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 30343956 DOI: 10.1053/J.Ajkd.2018.08.009  0.585
2018 Haase VH, Chertow GM, Block GA, Pergola PE, deGoma EM, Khawaja Z, Sharma A, Maroni BJ, McCullough PA. Effects of vadadustat on hemoglobin concentrations in patients receiving hemodialysis previously treated with erythropoiesis-stimulating agents. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 29672740 DOI: 10.1093/Ndt/Gfy055  0.627
2017 Stenvinkel P, Haase VH. Inflamed fat and mitochondrial dysfunction in end-stage renal disease links to hypoxia-could curcumin be of benefit? Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 32: 1263. PMID 28873972 DOI: 10.1093/Ndt/Gfx207  0.63
2017 Kobayashi H, Liu J, Urrutia AA, Burmakin M, Ishii K, Rajan M, Davidoff O, Saifudeen Z, Haase VH. Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development. Kidney International. PMID 28847650 DOI: 10.1016/J.Kint.2017.06.015  0.727
2017 Haase VH. Oxygen sensors as therapeutic targets in kidney disease. Nephrologie & Therapeutique. 13: S29-S34. PMID 28577740 DOI: 10.1016/J.Nephro.2017.01.015  0.684
2017 Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, ... ... Haase VH, et al. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. The Journal of Clinical Investigation. 127: 2438. PMID 28569735 DOI: 10.1172/JCI94890  0.578
2017 Haase VH. Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies. Experimental Cell Research. PMID 28483447 DOI: 10.1016/J.Yexcr.2017.05.004  0.691
2017 Stenvinkel P, Haase VH. Inflamed fat and mitochondrial dysfunction in end-stage renal disease links to hypoxia-could curcumin be of benefit? Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 28460128 DOI: 10.1093/ndt/gfx052  0.637
2017 Haase VH. HIF-prolyl hydroxylases as therapeutic targets in erythropoiesis and iron metabolism. Hemodialysis International. International Symposium On Home Hemodialysis. 21: S110-S124. PMID 28449418 DOI: 10.1111/Hdi.12567  0.667
2016 Urrutia AA, Afzal A, Nelson J, Davidoff O, Gross KW, Haase VH. Prolyl-4-hydroxylase 2 and 3 co-regulate murine erythropoietin in brain pericytes. Blood. PMID 27683416 DOI: 10.1182/Blood-2016-05-713545  0.672
2016 Pergola PE, Spinowitz BS, Hartman CS, Maroni BJ, Haase VH. Vadadustat, a novel oral HIF stabilizer, provides effective anemia treatment in nondialysis-dependent chronic kidney disease. Kidney International. PMID 27650732 DOI: 10.1016/J.Kint.2016.07.019  0.616
2016 Cho SH, Raybuck AL, Stengel K, Wei M, Beck TC, Volanakis E, Thomas JW, Hiebert S, Haase VH, Boothby MR. Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system. Nature. PMID 27501247 DOI: 10.1038/Nature19334  0.65
2016 Kobayashi H, Liu Q, Binns TC, Urrutia AA, Davidoff O, Kapitsinou PP, Pfaff AS, Olauson H, Wernerson A, Fogo AB, Fong GH, Gross KW, Haase VH. Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin. The Journal of Clinical Investigation. PMID 27088801 DOI: 10.1172/Jci83551  0.698
2016 Kapitsinou PP, Rajendran G, Astleford L, Michael M, Schonfeld MP, Fields T, Shay S, French JL, West J, Haase VH. The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice. Molecular and Cellular Biology. 36: 1584-94. PMID 26976644 DOI: 10.1128/Mcb.01055-15  0.659
2016 Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH. Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. The Journal of Clinical Investigation. 126: 1425-37. PMID 26927670 DOI: 10.1172/Jci74997  0.711
2016 Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH. Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin Journal of Clinical Investigation. 126: 1425-1437. DOI: 10.1172/JCI74997  0.683
2016 Kapitsinou P, Rajendran G, Astleford L, Schonfeld M, Michael M, Shay S, French J, West J, Haase V, Fields T. ID: 113: THE ENDOTHELIAL PHD2/HIF-2 AXIS REGULATES PULMONARY ARTERY PRESSURE IN MICE Journal of Investigative Medicine. 64: 961.2-962. DOI: 10.1136/Jim-2016-000120.103  0.668
2015 Bryant AJ, Carrick RP, McConaha ME, Jones BR, Shay SD, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, Tanjore H, Hemnes AR, Karwandyar AK, Polosukhin VV, Talati MA, ... ... Haase VH, et al. ENDOTHELIAL HIF SIGNALING REGULATES PULMONARY FIBROSIS-ASSOCIATED PULMONARY HYPERTENSION. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00258.2015. PMID 26637636 DOI: 10.1152/Ajplung.00258.2015  0.639
2015 Kapitsinou PP, Haase VH. Molecular mechanisms of ischemic preconditioning in the kidney. American Journal of Physiology. Renal Physiology. 309: F821-34. PMID 26311114 DOI: 10.1152/Ajprenal.00224.2015  0.685
2015 Haase VH. Inflammation and hypoxia in the kidney: friends or foes? Kidney International. 88: 213-5. PMID 26230196 DOI: 10.1038/Ki.2015.89  0.701
2015 Koury MJ, Haase VH. Anaemia in kidney disease: harnessing hypoxia responses for therapy. Nature Reviews. Nephrology. 11: 394-410. PMID 26055355 DOI: 10.1038/Nrneph.2015.82  0.701
2015 Pastor-Soler NM, Sutton TA, Mang HE, Kinlough CL, Gendler SJ, Madsen CS, Bastacky SI, Ho J, Al-Bataineh MM, Hallows KR, Singh S, Monga SP, Kobayashi H, Haase VH, Hughey RP. Muc1 is protective during kidney ischemia-reperfusion injury. American Journal of Physiology. Renal Physiology. 308: F1452-62. PMID 25925251 DOI: 10.1152/Ajprenal.00066.2015  0.721
2015 Haase VH. A breath of fresh air for diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 26: 239-41. PMID 25183808 DOI: 10.1681/Asn.2014080754  0.559
2015 Pergola PE, Spinowitz B, Haase VH, Hartman CS, Farmer TM, Polu KR, Maroni B, Shalwitz R. FO015AKB-6548, A NOVEL HYPOXIA-INDUCIBLE FACTOR PROLYL-HYDROXYLASE INHIBITOR (HIF-PHI) FOR THE TREATMENT OF ANEMIA IN PATIENTS WITH CHRONIC KIDNEY DISEASE NOT ON DIALYSIS (ND-CKD) Nephrology Dialysis Transplantation. 30: iii8-iii8. DOI: 10.1093/Ndt/Gfv138.02  0.67
2014 Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, ... ... Haase VH, et al. Erratum: Expression of concern: Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice (Journal of Clinical Investigation (2012) 122:2 (693-710) DOI: 10.1172/JCI60214)) Journal of Clinical Investigation. 124: 2807-2807. PMID 24812671 DOI: 10.1172/Jci76888  0.621
2014 Kapitsinou PP, Sano H, Michael M, Kobayashi H, Davidoff O, Bian A, Yao B, Zhang MZ, Harris RC, Duffy KJ, Erickson-Miller CL, Sutton TA, Haase VH. Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury. The Journal of Clinical Investigation. 124: 2396-409. PMID 24789906 DOI: 10.1172/Jci69073  0.703
2014 Tak E, Ridyard D, Kim JH, Zimmerman M, Werner T, Wang XX, Shabeka U, Seo SW, Christians U, Klawitter J, Moldovan R, Garcia G, Levi M, Haase V, Ravid K, et al. CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 25: 547-63. PMID 24262796 DOI: 10.1681/Asn.2012101014  0.599
2013 Lin Q, Huang Y, Booth CJ, Haase VH, Johnson RS, Celeste Simon M, Giordano FJ, Yun Z. Activation of hypoxia-inducible factor-2 in adipocytes results in pathological cardiac hypertrophy. Journal of the American Heart Association. 2: e000548. PMID 24326162 DOI: 10.1161/Jaha.113.000548  0.603
2013 Haase VH. Mechanisms of hypoxia responses in renal tissue. Journal of the American Society of Nephrology : Jasn. 24: 537-41. PMID 23334390 DOI: 10.1681/Asn.2012080855  0.681
2013 Haase VH. Regulation of erythropoiesis by hypoxia-inducible factors. Blood Reviews. 27: 41-53. PMID 23291219 DOI: 10.1016/J.Blre.2012.12.003  0.7
2012 Haase VH. Hypoxia-inducible factor signaling in the development of kidney fibrosis. Fibrogenesis & Tissue Repair. 5: S16. PMID 23259746 DOI: 10.1186/1755-1536-5-S1-S16  0.719
2012 Liu Q, Davidoff O, Niss K, Haase VH. Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis. The Journal of Clinical Investigation. 122: 4635-44. PMID 23114598 DOI: 10.1172/Jci63924  0.692
2012 Park SW, Kim M, Kim JY, Brown KM, Haase VH, D'Agati VD, Lee HT. Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia. Kidney International. 82: 878-91. PMID 22695326 DOI: 10.1038/Ki.2012.224  0.673
2012 Kobayashi H, Gilbert V, Liu Q, Kapitsinou PP, Unger TL, Rha J, Rivella S, Schlöndorff D, Haase VH. Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury. Journal of Immunology (Baltimore, Md. : 1950). 188: 5106-15. PMID 22490864 DOI: 10.4049/Jimmunol.1103377  0.721
2012 Haase VH. Renal cancer: oxygen meets metabolism. Experimental Cell Research. 318: 1057-67. PMID 22406000 DOI: 10.1016/J.Yexcr.2012.02.026  0.679
2012 Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, ... ... Haase VH, et al. Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice. The Journal of Clinical Investigation. 122: 693-710. PMID 22269324 DOI: 10.1172/Jci60214  0.68
2012 Kapitsinou PP, Jaffe J, Michael M, Swan CE, Duffy KJ, Erickson-Miller CL, Haase VH. Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury. American Journal of Physiology. Renal Physiology. 302: F1172-9. PMID 22262480 DOI: 10.1152/Ajprenal.00667.2011  0.712
2011 Gurley SB, Riquier-Brison AD, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM. AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metabolism. 13: 469-75. PMID 21459331 DOI: 10.1016/J.Cmet.2011.03.001  0.612
2011 Haase VH. Angiotensin II: breathtaking in the renal medulla. Kidney International. 79: 269-71. PMID 21228800 DOI: 10.1038/Ki.2010.434  0.64
2010 Bielesz B, Sirin Y, Si H, Niranjan T, Gruenwald A, Ahn S, Kato H, Pullman J, Gessler M, Haase VH, Susztak K. Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans. The Journal of Clinical Investigation. 120: 4040-54. PMID 20978353 DOI: 10.1172/Jci43025  0.672
2010 Kapitsinou PP, Haase VH. HO-1 in control of a self-eating kidney. Journal of the American Society of Nephrology : Jasn. 21: 1600-2. PMID 20829407 DOI: 10.1681/Asn.2010080876  0.685
2010 Welford SM, Dorie MJ, Li X, Haase VH, Giaccia AJ. Renal oxygenation suppresses VHL loss-induced senescence that is caused by increased sensitivity to oxidative stress. Molecular and Cellular Biology. 30: 4595-603. PMID 20679489 DOI: 10.1128/Mcb.01618-09  0.681
2010 Kapitsinou PP, Liu Q, Unger TL, Rha J, Davidoff O, Keith B, Epstein JA, Moores SL, Erickson-Miller CL, Haase VH. Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia. Blood. 116: 3039-48. PMID 20628150 DOI: 10.1182/Blood-2010-02-270322  0.726
2010 Hao CM, Haase VH. Sirtuins and their relevance to the kidney. Journal of the American Society of Nephrology : Jasn. 21: 1620-7. PMID 20595677 DOI: 10.1681/Asn.2010010046  0.647
2010 Haase VH. The sweet side of HIF. Kidney International. 78: 10-3. PMID 20551925 DOI: 10.1038/Ki.2010.112  0.718
2010 Weidemann A, Krohne TU, Aguilar E, Kurihara T, Takeda N, Dorrell MI, Simon MC, Haase VH, Friedlander M, Johnson RS. Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina. Glia. 58: 1177-85. PMID 20544853 DOI: 10.1002/Glia.20997  0.657
2010 Haase VH. Hypoxic regulation of erythropoiesis and iron metabolism. American Journal of Physiology. Renal Physiology. 299: F1-13. PMID 20444740 DOI: 10.1152/Ajprenal.00174.2010  0.714
2010 Seagroves TN, Peacock DL, Liao D, Schwab LP, Krueger R, Handorf CR, Haase VH, Johnson RS. VHL deletion impairs mammary alveologenesis but is not sufficient for mammary tumorigenesis. The American Journal of Pathology. 176: 2269-82. PMID 20382704 DOI: 10.2353/Ajpath.2010.090310  0.648
2010 Wei Q, Bhatt K, He HZ, Mi QS, Haase VH, Dong Z. Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury. Journal of the American Society of Nephrology : Jasn. 21: 756-61. PMID 20360310 DOI: 10.1681/Asn.2009070718  0.67
2010 Bajwa A, Jo SK, Ye H, Huang L, Dondeti KR, Rosin DL, Haase VH, Macdonald TL, Lynch KR, Okusa MD. Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury. Journal of the American Society of Nephrology : Jasn. 21: 955-65. PMID 20338995 DOI: 10.1681/Asn.2009060662  0.659
2010 Lee JJ, Natsuizaka M, Ohashi S, Wong GS, Takaoka M, Michaylira CZ, Budo D, Tobias JW, Kanai M, Shirakawa Y, Naomoto Y, Klein-Szanto AJ, Haase VH, Nakagawa H. Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis. Carcinogenesis. 31: 427-34. PMID 20042640 DOI: 10.1093/Carcin/Bgp326  0.662
2010 Bajwa A, Jo S, Ye H, Huang L, Dondeti KR, Rosin DL, Haase VH, Macdonald TL, Lynch KR, Okusa MD. 42: Activation of Proximal Tubule Sphingosine 1-Phosphate Receptor 1 Protects Kidneys From Ischemia Reperfusion Injury Independent of Lymphocytes American Journal of Kidney Diseases. 55: B42. DOI: 10.1053/J.Ajkd.2010.02.049  0.612
2009 Haase VH. Pathophysiological Consequences of HIF Activation: HIF as a modulator of fibrosis. Annals of the New York Academy of Sciences. 1177: 57-65. PMID 19845607 DOI: 10.1111/J.1749-6632.2009.05030.X  0.712
2009 Weidemann A, Kerdiles YM, Knaup KX, Rafie CA, Boutin AT, Stockmann C, Takeda N, Scadeng M, Shih AY, Haase VH, Simon MC, Kleinfeld D, Johnson RS. The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. The Journal of Clinical Investigation. 119: 3373-83. PMID 19809162 DOI: 10.1172/Jci39378  0.693
2009 Haase VH. The VHL tumor suppressor: master regulator of HIF. Current Pharmaceutical Design. 15: 3895-903. PMID 19671042 DOI: 10.2174/138161209789649394  0.71
2009 Haase VH. Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease. Kidney International. 76: 492-9. PMID 19536078 DOI: 10.1038/Ki.2009.222  0.656
2009 Rankin EB, Rha J, Selak MA, Unger TL, Keith B, Liu Q, Haase VH. Hypoxia-inducible factor 2 regulates hepatic lipid metabolism. Molecular and Cellular Biology. 29: 4527-38. PMID 19528226 DOI: 10.1128/Mcb.00200-09  0.771
2008 Kimura K, Iwano M, Higgins DF, Yamaguchi Y, Nakatani K, Harada K, Kubo A, Akai Y, Rankin EB, Neilson EG, Haase VH, Saito Y. Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis. American Journal of Physiology. Renal Physiology. 295: F1023-9. PMID 18667485 DOI: 10.1152/Ajprenal.90209.2008  0.8
2008 Haase VH. Hemoglobin in the kidney: breaking with traditional dogma. Journal of the American Society of Nephrology : Jasn. 19: 1440-1. PMID 18614770 DOI: 10.1681/Asn.2008060594  0.601
2008 Rankin EB, Rha J, Unger TL, Wu CH, Shutt HP, Johnson RS, Simon MC, Keith B, Haase VH. Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice. Oncogene. 27: 5354-8. PMID 18490920 DOI: 10.1038/Onc.2008.160  0.79
2008 Shah YM, Ito S, Morimura K, Chen C, Yim SH, Haase VH, Gonzalez FJ. Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade. Gastroenterology. 134: 2036-48, 2048.e1-3. PMID 18439915 DOI: 10.1053/J.Gastro.2008.03.009  0.66
2008 Peng M, Falk MJ, Haase VH, King R, Polyak E, Selak M, Yudkoff M, Hancock WW, Meade R, Saiki R, Lunceford AL, Clarke CF, Gasser DL. Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease. Plos Genetics. 4: e1000061. PMID 18437205 DOI: 10.1371/Journal.Pgen.1000061  0.651
2008 Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, et al. Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell. 133: 223-34. PMID 18423195 DOI: 10.1016/J.Cell.2008.02.038  0.685
2008 Higgins DF, Kimura K, Iwano M, Haase VH. Hypoxia-inducible factor signaling in the development of tissue fibrosis. Cell Cycle (Georgetown, Tex.). 7: 1128-32. PMID 18418042 DOI: 10.4161/Cc.7.9.5804  0.734
2008 Maltzman JS, Haase VH. Low oxygen stimulates the immune system. Kidney International. 73: 797-9. PMID 18340350 DOI: 10.1038/Ki.2008.15  0.657
2008 Kapitsinou PP, Haase VH. The VHL tumor suppressor and HIF: insights from genetic studies in mice. Cell Death and Differentiation. 15: 650-9. PMID 18219317 DOI: 10.1038/Sj.Cdd.4402313  0.695
2007 Higgins DF, Kimura K, Bernhardt WM, Shrimanker N, Akai Y, Hohenstein B, Saito Y, Johnson RS, Kretzler M, Cohen CD, Eckardt KU, Iwano M, Haase VH. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. The Journal of Clinical Investigation. 117: 3810-20. PMID 18037992 DOI: 10.1172/Jci30487  0.732
2007 Brukamp K, Jim B, Moeller MJ, Haase VH. Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease. American Journal of Physiology. Renal Physiology. 293: F1397-407. PMID 17609290 DOI: 10.1152/Ajprenal.00133.2007  0.713
2007 Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, Johnson RS. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). The Journal of Clinical Investigation. 117: 1926-32. PMID 17557118 DOI: 10.1172/Jci31370  0.757
2007 Wang Y, Wan C, Deng L, Liu X, Cao X, Gilbert SR, Bouxsein ML, Faugere MC, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E, Clemens TL. The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. The Journal of Clinical Investigation. 117: 1616-26. PMID 17549257 DOI: 10.1172/Jci31581  0.64
2007 Rankin EB, Biju MP, Liu Q, Unger TL, Rha J, Johnson RS, Simon MC, Keith B, Haase VH. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. The Journal of Clinical Investigation. 117: 1068-77. PMID 17404621 DOI: 10.1172/Jci30117  0.779
2007 Blouw B, Haase VH, Song H, Bergers G, Johnson RS. Loss of vascular endothelial growth factor expression reduces vascularization, but not growth, of tumors lacking the Von Hippel-Lindau tumor suppressor gene. Oncogene. 26: 4531-40. PMID 17297464 DOI: 10.1038/Sj.Onc.1210249  0.621
2007 Park SK, Haase VH, Johnson RS. von Hippel Lindau tumor suppressor regulates hepatic glucose metabolism by controlling expression of glucose transporter 2 and glucose 6-phosphatase. International Journal of Oncology. 30: 341-8. PMID 17203215 DOI: 10.3892/Ijo.30.2.341  0.644
2007 Brukamp K, Jim B, Moeller MJ, Holzman LB, Haase VH. Podocyte‐specific Vhlh loss demonstrates role for hypoxia‐inducible transcription factors (HIFs) in glomerular disease pathogenesis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A504-A  0.647
2006 Ding M, Cui S, Li C, Jothy S, Haase V, Steer BM, Marsden PA, Pippin J, Shankland S, Rastaldi MP, Cohen CD, Kretzler M, Quaggin SE. Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nature Medicine. 12: 1081-7. PMID 16906157 DOI: 10.1038/Nm1460  0.677
2006 Wang J, Biju MP, Wang MH, Haase VH, Dong Z. Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: involvement of mitochondrial inhibition and p53 suppression. Journal of the American Society of Nephrology : Jasn. 17: 1875-85. PMID 16762987 DOI: 10.1681/Asn.2005121371  0.676
2006 Haase VH. Hypoxia-inducible factors in the kidney. American Journal of Physiology. Renal Physiology. 291: F271-81. PMID 16554418 DOI: 10.1152/Ajprenal.00071.2006  0.718
2006 Tang N, Mack F, Haase VH, Simon MC, Johnson RS. pVHL function is essential for endothelial extracellular matrix deposition. Molecular and Cellular Biology. 26: 2519-30. PMID 16537898 DOI: 10.1128/Mcb.26.7.2519-2530.2006  0.657
2006 Haase VH. The VHL/HIF oxygen-sensing pathway and its relevance to kidney disease. Kidney International. 69: 1302-7. PMID 16531988 DOI: 10.1038/Sj.Ki.5000221  0.715
2006 Liu Y, Pop R, Sadegh C, Brugnara C, Haase VH, Socolovsky M. Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo. Blood. 108: 123-33. PMID 16527892 DOI: 10.1182/Blood-2005-11-4458  0.6
2006 Rankin EB, Tomaszewski JE, Haase VH. Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor. Cancer Research. 66: 2576-83. PMID 16510575 DOI: 10.1158/0008-5472.Can-05-3241  0.792
2006 Ding M, Cui S, Li C, Jothy S, Haase V, Steer B, Marsden P, Pippin J, Shankland S, Rastaldi M, Cohen C, Kretzler M, Quaggin S. Faulty Podocyte Hypoxia Sensing—A Novel Pathway for Rapidly Progressive Glomerulonephritis Journal of the American Society of Nephrology. 17: 3267-3272. DOI: 10.1681/Asn.2006101148  0.605
2005 Neumann AK, Yang J, Biju MP, Joseph SK, Johnson RS, Haase VH, Freedman BD, Turka LA. Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 102: 17071-6. PMID 16286658 DOI: 10.1073/Pnas.0506070102  0.642
2005 Biju MP, Akai Y, Shrimanker N, Haase VH. Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent. American Journal of Physiology. Renal Physiology. 289: F1217-26. PMID 16048903 DOI: 10.1152/Ajprenal.00233.2005  0.703
2005 Haase VH. The VHL tumor suppressor in development and disease: functional studies in mice by conditional gene targeting. Seminars in Cell & Developmental Biology. 16: 564-74. PMID 15908240 DOI: 10.1016/J.Semcdb.2005.03.006  0.692
2005 Mack FA, Patel JH, Biju MP, Haase VH, Simon MC. Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27. Molecular and Cellular Biology. 25: 4565-78. PMID 15899860 DOI: 10.1128/Mcb.25.11.4565-4578.2005  0.652
2005 Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH. Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. Molecular and Cellular Biology. 25: 3163-72. PMID 15798202 DOI: 10.1128/Mcb.25.8.3163-3172.2005  0.786
2005 Karhausen J, Haase VH, Colgan SP. Inflammatory hypoxia: role of hypoxia-inducible factor. Cell Cycle (Georgetown, Tex.). 4: 256-8. PMID 15655360 DOI: 10.4161/Cc.4.2.1407  0.661
2004 Karhausen J, Furuta GT, Tomaszewski JE, Johnson RS, Colgan SP, Haase VH. Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis. The Journal of Clinical Investigation. 114: 1098-106. PMID 15489957 DOI: 10.1172/Jci21086  0.687
2004 Biju MP, Neumann AK, Bensinger SJ, Johnson RS, Turka LA, Haase VH. Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes. Molecular and Cellular Biology. 24: 9038-47. PMID 15456877 DOI: 10.1128/Mcb.24.20.9038-9047.2004  0.688
2004 Higgins DF, Biju MP, Akai Y, Wutz A, Johnson RS, Haase VH. Hypoxic induction of Ctgf is directly mediated by Hif-1. American Journal of Physiology. Renal Physiology. 287: F1223-32. PMID 15315937 DOI: 10.1152/Ajprenal.00245.2004  0.72
2004 Pfander D, Kobayashi T, Knight MC, Zelzer E, Chan DA, Olsen BR, Giaccia AJ, Johnson RS, Haase VH, Schipani E. Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development (Cambridge, England). 131: 2497-508. PMID 15128677 DOI: 10.1242/Dev.01138  0.654
2003 Higgins DF, Lappin DW, Kieran NE, Anders HJ, Watson RW, Strutz F, Schlondorff D, Haase VH, Fitzpatrick JM, Godson C, Brady HR. DNA oligonucleotide microarray technology identifies fisp-12 among other potential fibrogenic genes following murine unilateral ureteral obstruction (UUO): modulation during epithelial-mesenchymal transition. Kidney International. 64: 2079-91. PMID 14633130 DOI: 10.1046/J.1523-1755.2003.00306.X  0.606
2003 Park SK, Dadak AM, Haase VH, Fontana L, Giaccia AJ, Johnson RS. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha. Molecular and Cellular Biology. 23: 4959-71. PMID 12832481 DOI: 10.1128/Mcb.23.14.4959-4971.2003  0.655
2003 Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 112: 645-57. PMID 12628185 DOI: 10.1016/S0092-8674(03)00154-5  0.722
2003 Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. Erratum: HIF-1α is essential for myeloid cell-mediated inflammation (Cell 112:5 (648)) Cell. 113. DOI: 10.1016/S0092-8674(03)00311-8  0.671
2001 Socolovsky M, Nam HS, Fleming MD, Haase VH, Brugnara C, Lodish HF. Ineffective erythropoiesis in Stat5a-/-5b-/- mice due to decreased survival of early erythroblasts Blood. 98: 3261-3273. PMID 11719363 DOI: 10.1182/Blood.V98.12.3261  0.609
2001 Haase VH, Glickman JN, Socolovsky M, Jaenisch R. Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 98: 1583-8. PMID 11171994 DOI: 10.1073/Pnas.98.4.1583  0.699
1997 Snijders AJ, Ho SC, Haase VH, Pillai S, Bernards A. A lymphocyte-specific Ltk tyrosine kinase isoform is retained in the endoplasmic reticulum in association with calnexin Journal of Biological Chemistry. 272: 1297-1301. PMID 8995435 DOI: 10.1074/Jbc.272.2.1297  0.597
1994 Haase VH, Trofatter JA, MacCollin M, Tarttelin E, Gusella JF, Ramesh V. The murine NF2 homologue encodes a highly conserved merlin protein with alternative forms. Human Molecular Genetics. 3: 407-11. PMID 8012352 DOI: 10.1093/Hmg/3.3.407  0.571
1993 Voigt M, Geißler U, Haase V, Voigt B, Hallensleben ML, Toppare L. Derivatives of poly(pyrrole) with deconjugated carbonyl substituents in β-position Synthetic Metals. 55: 1441-1446. DOI: 10.1016/0379-6779(93)90265-X  0.482
1992 Bernards A, Haase VH, Murthy AE, Menon A, Hannigan GE, Gusella JF. Complete human NF1 cDNA sequence: two alternatively spliced mRNAs and absence of expression in a neuroblastoma line. Dna and Cell Biology. 11: 727-34. PMID 1457041 DOI: 10.1089/Dna.1992.11.727  0.575
Show low-probability matches.