Year |
Citation |
Score |
2024 |
Martin MF, Bonaventure B, McCray NE, Peersen OB, Rozen-Gagnon K, Stapleford KA. Distinct chikungunya virus polymerase palm subdomains contribute to virus replication and virion assembly. Biorxiv : the Preprint Server For Biology. PMID 38293111 DOI: 10.1101/2024.01.15.575630 |
0.402 |
|
2023 |
Decombe A, Peersen O, Sutto-Ortiz P, Chamontin C, Piorkowski G, Canard B, Nisole S, Decroly E. Internal RNA 2'-O-methylation on the HIV-1 genome impairs reverse transcription. Nucleic Acids Research. PMID 38015463 DOI: 10.1093/nar/gkad1134 |
0.313 |
|
2023 |
Campagnola G, Peersen O. Co-folding and RNA activation of poliovirus 3C polyprotein precursors. The Journal of Biological Chemistry. 299: 105258. PMID 37717698 DOI: 10.1016/j.jbc.2023.105258 |
0.496 |
|
2022 |
Campagnola G, Govindarajan V, Pelletier A, Canard B, Peersen OB. The SARS-CoV nsp12 Polymerase Active Site Is Tuned for Large-Genome Replication. Journal of Virology. 96: e0067122. PMID 35924919 DOI: 10.1128/jvi.00671-22 |
0.441 |
|
2020 |
Shannon A, Selisko B, Le NT, Huchting J, Touret F, Piorkowski G, Fattorini V, Ferron F, Decroly E, Meier C, Coutard B, Peersen O, Canard B. Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis. Nature Communications. 11: 4682. PMID 32943628 DOI: 10.1038/S41467-020-18463-Z |
0.493 |
|
2020 |
Kempf BJ, Watkins CL, Peersen OB, Barton DJ. An Extended Primer Grip of Picornavirus Polymerase Facilitates Sexual RNA Replication Mechanisms. Journal of Virology. PMID 32522851 DOI: 10.1128/Jvi.00835-20 |
0.476 |
|
2020 |
Watkins CL, Kempf BJ, Beaucourt S, Barton DJ, Peersen OB. Picornaviral polymerase domain exchanges reveal a modular basis for distinct biochemical activities of viral RNA-dependent RNA polymerases. The Journal of Biological Chemistry. PMID 32493771 DOI: 10.1074/Jbc.Ra120.013906 |
0.536 |
|
2020 |
Shannon A, Le NT, Selisko B, Eydoux C, Alvarez K, Guillemot JC, Decroly E, Peersen O, Ferron F, Canard B. Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites. Antiviral Research. 178: 104793. PMID 32283108 DOI: 10.1016/J.Antiviral.2020.104793 |
0.498 |
|
2019 |
Peersen OB. A Comprehensive Superposition of Viral Polymerase Structures. Viruses. 11. PMID 31412589 DOI: 10.3390/V11080745 |
0.472 |
|
2019 |
Kempf BJ, Watkins CL, Peersen OB, Barton DJ. Picornavirus RNA Recombination Counteracts Error Catastrophe. Journal of Virology. PMID 31068422 DOI: 10.1128/Jvi.00652-19 |
0.495 |
|
2018 |
Martínez-Sobrido L, Peersen O, Nogales A. Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine. Viruses. 10. PMID 30326610 DOI: 10.3390/V10100560 |
0.336 |
|
2017 |
Farrell KB, McDonald S, Lamb AK, Worcester C, Peersen OB, Di Pietro SM. Novel function of a dynein light chain in actin assembly during clathrin-mediated endocytosis. The Journal of Cell Biology. PMID 28706108 DOI: 10.1083/Jcb.201604123 |
0.324 |
|
2017 |
Rai DK, Diaz-San Segundo F, Campagnola G, Keith A, Schafer EA, Kloc A, de Los Santos T, Peersen O, Rieder E. Attenuation of Foot-and-Mouth Disease Virus by Engineering Viral Polymerase Fidelity. Journal of Virology. PMID 28515297 DOI: 10.1128/Jvi.00081-17 |
0.438 |
|
2017 |
Peersen OB. Picornaviral Polymerase Structure, Function, and Fidelity Modulation. Virus Research. PMID 28163093 DOI: 10.1016/J.Virusres.2017.01.026 |
0.568 |
|
2016 |
Kempf BJ, Peersen OB, Barton DJ. Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance. Journal of Virology. PMID 27412593 DOI: 10.1128/Jvi.00078-16 |
0.533 |
|
2016 |
Svensen N, Peersen OB, Jaffrey SR. Peptide Synthesis on a Next-Generation DNA Sequencing Platform. Chembiochem : a European Journal of Chemical Biology. PMID 27385640 DOI: 10.1002/Cbic.201600298 |
0.354 |
|
2016 |
Karr JP, Peersen OB. ATP is an allosteric inhibitor of Coxsackievirus B3 Polymerase. Biochemistry. PMID 27319576 DOI: 10.1021/Acs.Biochem.6B00467 |
0.524 |
|
2016 |
Sexton NR, Smith EC, Blanc H, Vignuzzi M, Peersen O, Denison MR. Homology-based identification of a mutation in the coronavirus RNA-dependent RNA polymerase that confers resistance to multiple mutagens. Journal of Virology. PMID 27279608 DOI: 10.1128/Jvi.00080-16 |
0.524 |
|
2016 |
McDonald S, Block A, Beaucourt S, Moratorio G, Vignuzzi M, Peersen OB. Design of a Genetically Stable High-Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in vivo. The Journal of Biological Chemistry. PMID 27137934 DOI: 10.1074/Jbc.M116.726596 |
0.489 |
|
2015 |
Campagnola G, Nepal K, Schroder BW, Peersen OB, Krapf D. Superdiffusive motion of membrane-targeting C2 domains. Scientific Reports. 5: 17721. PMID 26639944 DOI: 10.1038/Srep17721 |
0.305 |
|
2015 |
Campagnola G, McDonald S, Beaucourt S, Vignuzzi M, Peersen OB. Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases. Journal of Virology. 89: 275-86. PMID 25320316 DOI: 10.1128/Jvi.01574-14 |
0.528 |
|
2014 |
Sholders AJ, Peersen OB. Distinct conformations of a putative translocation element in poliovirus polymerase. Journal of Molecular Biology. 426: 1407-19. PMID 24424421 DOI: 10.1016/J.Jmb.2013.12.031 |
0.745 |
|
2013 |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB. Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One. 8: e60272. PMID 23667424 DOI: 10.1371/Journal.Pone.0060272 |
0.554 |
|
2013 |
Springer CL, Huntoon HP, Peersen OB. Polyprotein context regulates the activity of poliovirus 2CATPase bound to bilayer nanodiscs. Journal of Virology. 87: 5994-6004. PMID 23514879 DOI: 10.1128/Jvi.03491-12 |
0.707 |
|
2013 |
Kempf BJ, Kelly MM, Springer CL, Peersen OB, Barton DJ. Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA. Journal of Virology. 87: 5629-44. PMID 23468507 DOI: 10.1128/Jvi.02590-12 |
0.732 |
|
2013 |
Nayak RK, Faulkner R, Peersen OB, Orden AKV. Loop Length and Counter Ion Dependent Folding Kinetics and Thermodynamic Stability of Nucleic Acid Hairpin Biophysical Journal. 104: 412a. DOI: 10.1016/J.Bpj.2012.11.2298 |
0.338 |
|
2012 |
Gnädig NF, Beaucourt S, Campagnola G, Bordería AV, Sanz-Ramos M, Gong P, Blanc H, Peersen OB, Vignuzzi M. Coxsackievirus B3 mutator strains are attenuated in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: E2294-303. PMID 22853955 DOI: 10.1073/Pnas.1204022109 |
0.401 |
|
2012 |
Kortus MG, Kempf BJ, Haworth KG, Barton DJ, Peersen OB. A template RNA entry channel in the fingers domain of the poliovirus polymerase. Journal of Molecular Biology. 417: 263-78. PMID 22321798 DOI: 10.1016/J.Jmb.2012.01.049 |
0.559 |
|
2011 |
Campagnola G, Gong P, Peersen OB. High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. Antiviral Research. 91: 241-51. PMID 21722674 DOI: 10.1016/J.Antiviral.2011.06.006 |
0.543 |
|
2010 |
Gong P, Peersen OB. Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 107: 22505-10. PMID 21148772 DOI: 10.1073/Pnas.1007626107 |
0.571 |
|
2010 |
Hobdey SE, Kempf BJ, Steil BP, Barton DJ, Peersen OB. Poliovirus polymerase residue 5 plays a critical role in elongation complex stability. Journal of Virology. 84: 8072-84. PMID 20534858 DOI: 10.1128/Jvi.02147-09 |
0.789 |
|
2009 |
Gong P, Campagnola G, Peersen OB. A quantitative stopped-flow fluorescence assay for measuring polymerase elongation rates. Analytical Biochemistry. 391: 45-55. PMID 19406094 DOI: 10.1016/J.Ab.2009.04.035 |
0.452 |
|
2009 |
Geiss BJ, Thompson AA, Andrews AJ, Sons RL, Gari HH, Keenan SM, Peersen OB. Analysis of flavivirus NS5 methyltransferase cap binding. Journal of Molecular Biology. 385: 1643-54. PMID 19101564 DOI: 10.1016/J.Jmb.2008.11.058 |
0.653 |
|
2008 |
Campagnola G, Weygandt M, Scoggin K, Peersen O. Crystal structure of coxsackievirus B3 3Dpol highlights the functional importance of residue 5 in picornavirus polymerases Journal of Virology. 82: 9458-9464. PMID 18632862 DOI: 10.1128/Jvi.00647-08 |
0.423 |
|
2007 |
Mestas SP, Sholders AJ, Peersen OB. A fluorescence polarization-based screening assay for nucleic acid polymerase elongation activity. Analytical Biochemistry. 365: 194-200. PMID 17475199 DOI: 10.1016/J.Ab.2007.03.039 |
0.713 |
|
2007 |
Thompson AA, Albertini RA, Peersen OB. Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions. Journal of Molecular Biology. 366: 1459-74. PMID 17223130 DOI: 10.1016/J.Jmb.2006.11.070 |
0.632 |
|
2006 |
Tellez AB, Crowder S, Spagnolo JF, Thompson AA, Peersen OB, Brutlag DL, Kirkegaard K. Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer. Journal of Molecular Biology. 357: 665-75. PMID 16427083 DOI: 10.1016/J.Jmb.2005.12.044 |
0.674 |
|
2004 |
Thompson AA, Peersen OB. Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase. The Embo Journal. 23: 3462-71. PMID 15306852 DOI: 10.1038/Sj.Emboj.7600357 |
0.671 |
|
2004 |
Nyborg JK, Peersen OB. That zincing feeling: the effects of EDTA on the behaviour of zinc-binding transcriptional regulators. The Biochemical Journal. 381: e3-4. PMID 15270700 DOI: 10.1042/Bj20041096 |
0.349 |
|
2002 |
Smith SO, Smith C, Shekar S, Peersen O, Ziliox M, Aimoto S. Transmembrane interactions in the activation of the Neu receptor tyrosine kinase Biochemistry. 41: 9321-9332. PMID 12135353 DOI: 10.1021/Bi012117L |
0.325 |
|
2002 |
Peersen OB, Ruggles JA, Schultz SC. Dimeric structure of the Oxytricha nova telomere end-binding protein alpha-subunit bound to ssDNA. Nature Structural Biology. 9: 182-7. PMID 11836536 DOI: 10.1038/Nsb761 |
0.655 |
|
1997 |
Peersen OB, Madsen TS, Falke JJ. Intermolecular tuning of calmodulin by target peptides and proteins: differential effects on Ca2+ binding and implications for kinase activation. Protein Science : a Publication of the Protein Society. 6: 794-807. PMID 9098889 DOI: 10.1002/Pro.5560060406 |
0.549 |
|
1994 |
Falke JJ, Drake SK, Hazard AL, Peersen OB. Molecular tuning of ion binding to calcium signaling proteins. Quarterly Reviews of Biophysics. 27: 219-90. PMID 7899550 DOI: 10.1017/S0033583500003012 |
0.706 |
|
1992 |
Smith SO, Peersen OB. Solid-state NMR approaches for studying membrane protein structure. Annual Review of Biophysics and Biomolecular Structure. 21: 25-47. PMID 1525470 DOI: 10.1146/Annurev.Bb.21.060192.000325 |
0.318 |
|
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