| Year |
Citation |
Score |
| 2021 |
Cheng J, Tsuda M, Okolotowicz K, Dwyer M, Bushway PJ, Colas AR, Lancman JJ, Schade D, Perea-Gil I, Bruyneel AAN, Lee J, Vadgama N, Quach J, McKeithan WL, Biechele TL, ... ... Mercola M, et al. Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness. Cell Chemical Biology. PMID 33503403 DOI: 10.1016/j.chembiol.2021.01.001 |
0.721 |
|
| 2020 |
McKeithan WL, Feyen DAM, Bruyneel AAN, Okolotowicz KJ, Ryan DA, Sampson KJ, Potet F, Savchenko A, Gómez-Galeno J, Vu M, Serrano R, George AL, Kass RS, Cashman JR, Mercola M. Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity. Cell Stem Cell. PMID 32931730 DOI: 10.1016/J.Stem.2020.08.003 |
0.339 |
|
| 2020 |
Levitas A, Muhammad E, Zhang Y, Perea Gil I, Serrano R, Diaz N, Arafat M, Gavidia AA, Kapiloff MS, Mercola M, Etzion Y, Parvari R, Karakikes I. A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy. Plos Genetics. 16: e1009000. PMID 32925938 DOI: 10.1371/Journal.Pgen.1009000 |
0.323 |
|
| 2020 |
Briganti F, Sun H, Wei W, Wu J, Zhu C, Liss M, Karakikes I, Rego S, Cipriano A, Snyder M, Meder B, Xu Z, Millat G, Gotthardt M, Mercola M, et al. iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy. Cell Reports. 32: 108117. PMID 32905764 DOI: 10.1016/J.Celrep.2020.108117 |
0.341 |
|
| 2020 |
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, ... ... Mercola M, et al. Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes. Cell Reports. 32: 107925. PMID 32697997 DOI: 10.1016/J.Celrep.2020.107925 |
0.343 |
|
| 2019 |
Bruyneel AAN, Colas AR, Karakikes I, Mercola M. AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes. Plos One. 14: e0226694. PMID 31877162 DOI: 10.1371/Journal.Pone.0226694 |
0.696 |
|
| 2019 |
Halver J, Wenzel K, Sendker J, Carrillo García C, Erdelmeier CAJ, Willems E, Mercola M, Symma N, Könemann S, Koch E, Hensel A, Schade D. Extract WS®1442 Stimulates Cardiomyogenesis and Angiogenesis From Stem Cells: A Possible New Pharmacology for Hawthorn? Frontiers in Pharmacology. 10: 1357. PMID 31849643 DOI: 10.3389/Fphar.2019.01357 |
0.436 |
|
| 2019 |
Hurtado C, Safarova A, Smith M, Chung R, Bruyneel AAN, Gomez-Galeno J, Oswald F, Larson CJ, Cashman JR, Ruiz-Lozano P, Janiak P, Suzuki T, Mercola M. Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ. Scientific Reports. 9: 10811. PMID 31346210 DOI: 10.1038/S41598-019-46948-5 |
0.388 |
|
| 2019 |
Hnatiuk A, Mercola M. Stars in the Night Sky: iPSC-Cardiomyocytes Return the Patient Context to Drug Screening. Cell Stem Cell. 24: 506-507. PMID 30951657 DOI: 10.1016/J.Stem.2019.03.013 |
0.359 |
|
| 2018 |
Sharma A, McKeithan WL, Serrano R, Kitani T, Burridge PW, Del Álamo JC, Mercola M, Wu JC. Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity. Nature Protocols. PMID 30413796 DOI: 10.1038/S41596-018-0076-8 |
0.34 |
|
| 2018 |
Gómez-Galeno JE, Hurtado C, Cheng J, Yardimci C, Mercola M, Cashman JR. b-Annulated 1,4-dihydropyridines as Notch inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 30201292 DOI: 10.1016/J.Bmcl.2018.09.002 |
0.319 |
|
| 2018 |
Bruyneel AA, McKeithan WL, Feyen DA, Mercola M. Will iPSC-cardiomyocytes revolutionize the discovery of drugs for heart disease? Current Opinion in Pharmacology. 42: 55-61. PMID 30081259 DOI: 10.1016/J.Coph.2018.07.003 |
0.332 |
|
| 2018 |
Cheng J, Dwyer M, Okolotowicz KJ, Mercola M, Cashman JR. A novel inhibitor targets both Wnt signaling and ATM/p53 in colorectal cancer. Cancer Research. PMID 30032112 DOI: 10.1158/0008-5472.Can-17-2642 |
0.317 |
|
| 2018 |
Bruyneel AAN, McKeithan WL, Feyen DAM, Mercola M. Using iPSC Models to Probe Regulation of Cardiac Ion Channel Function. Current Cardiology Reports. 20: 57. PMID 29802473 DOI: 10.1007/S11886-018-1000-0 |
0.308 |
|
| 2018 |
Diez-Cuñado M, Wei K, Bushway PJ, Maurya MR, Perera R, Subramaniam S, Ruiz-Lozano P, Mercola M. miRNAs that Induce Human Cardiomyocyte Proliferation Converge on the Hippo Pathway. Cell Reports. 23: 2168-2174. PMID 29768213 DOI: 10.1016/J.Celrep.2018.04.049 |
0.534 |
|
| 2018 |
Jung JH, Tada Y, Bornstaedt D, Wahlquist C, Mercola M, Woo Y, Yang P. EXOSOMAL MIR-106A-363 CLUSTER FROM THE HYPOXIC HUMAN IPSC-DERIVED CARDIOMYOCYTES RESTORE THE ISCHEMIC MYOCARDIUM Journal of the American College of Cardiology. 71: A14. DOI: 10.1016/S0735-1097(18)30555-2 |
0.354 |
|
| 2017 |
McKeithan WL, Savchenko A, Yu MS, Cerignoli F, Bruyneel AAN, Price JH, Colas AR, Miller EW, Cashman JR, Mercola M. An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. Frontiers in Physiology. 8: 766. PMID 29075196 DOI: 10.3389/Fphys.2017.00766 |
0.723 |
|
| 2017 |
Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, ... ... Mercola M, et al. Id genes are essential for early heart formation. Genes & Development. PMID 28794185 DOI: 10.1101/Gad.300400.117 |
0.775 |
|
| 2017 |
Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, ... ... Mercola M, et al. High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Science Translational Medicine. 9. PMID 28202772 DOI: 10.1126/Scitranslmed.Aaf2584 |
0.387 |
|
| 2017 |
Crespo R, Wei K, Rodenak-Kladniew B, Mercola M, Ruiz-Lozano P, Hurtado C. Effect of geraniol on rat cardiomyocytes and its potential use as a cardioprotective natural compound. Life Sciences. PMID 28131760 DOI: 10.1016/J.Lfs.2017.01.008 |
0.516 |
|
| 2016 |
Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, et al. miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification. Proceedings of the National Academy of Sciences of the United States of America. PMID 27512039 DOI: 10.1073/Pnas.1608256113 |
0.344 |
|
| 2016 |
Liu Y, Mercola M, Schwartz RJ. The All-Chemical Approach: A Solution for Converting Fibroblasts Into Myocytes. Circulation Research. 119: 505-7. PMID 27492839 DOI: 10.1161/Circresaha.116.309146 |
0.359 |
|
| 2016 |
Díaz-Trelles R, Scimia MC, Bushway P, Tran D, Monosov A, Monosov E, Peterson K, Rentschler S, Cabrales P, Ruiz-Lozano P, Mercola M. Notch-independent RBPJ controls angiogenesis in the adult heart. Nature Communications. 7: 12088. PMID 27357444 DOI: 10.1038/Ncomms12088 |
0.393 |
|
| 2016 |
Del Álamo JC, Lemons D, Serrano R, Savchenko A, Cerignoli F, Bodmer R, Mercola M. High throughput physiological screening of iPSC-derived cardiomyocytes for drug development. Biochimica Et Biophysica Acta. PMID 26952934 DOI: 10.1016/J.Bbamcr.2016.03.003 |
0.353 |
|
| 2015 |
Wei K, Serpooshan V, Hurtado C, Diez-Cuñado M, Zhao M, Maruyama S, Zhu W, Fajardo G, Noseda M, Nakamura K, Tian X, Liu Q, Wang A, Matsuura Y, Bushway P, ... ... Mercola M, et al. Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature. PMID 26375005 DOI: 10.1038/Nature15372 |
0.579 |
|
| 2015 |
Cunningham TJ, Brade T, Sandell LL, Lewandoski M, Trainor PA, Colas A, Mercola M, Duester G. Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis. Plos One. 10: e0137894. PMID 26368825 DOI: 10.1371/Journal.Pone.0137894 |
0.729 |
|
| 2015 |
Okolotowicz KJ, Bushway P, Lanier M, Gilley C, Mercola M, Cashman JR. 1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells. Bioorganic & Medicinal Chemistry. 23: 5282-92. PMID 26278027 DOI: 10.1016/J.Bmc.2015.07.073 |
0.437 |
|
| 2015 |
Wei K, Díaz-Trelles R, Liu Q, Diez-Cuñado M, Scimia MC, Cai W, Sawada J, Komatsu M, Boyle JJ, Zhou B, Ruiz-Lozano P, Mercola M. Developmental origin of age-related coronary artery disease. Cardiovascular Research. 107: 287-94. PMID 26054850 DOI: 10.1093/Cvr/Cvv167 |
0.5 |
|
| 2015 |
Cabral-Teixeira J, Martinez-Fernandez A, Cai W, Terzic A, Mercola M, Willems E. Cholesterol-derived glucocorticoids control early fate specification in embryonic stem cells. Stem Cell Research. 15: 88-95. PMID 26024790 DOI: 10.1016/J.Scr.2015.04.010 |
0.478 |
|
| 2015 |
Spiering S, Davidovics H, Bushway PJ, Mercola M, Willems E. High content screening for modulators of cardiac differentiation in human pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 1263: 43-61. PMID 25618335 DOI: 10.1007/978-1-4939-2269-7_4 |
0.396 |
|
| 2015 |
Banerjee I, Carrion K, Serrano R, Dyo J, Sasik R, Lund S, Willems E, Aceves S, Meili R, Mercola M, Chen J, Zambon A, Hardiman G, Doherty TA, Lange S, et al. Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling. Journal of Molecular and Cellular Cardiology. 79: 133-44. PMID 25446186 DOI: 10.1016/J.Yjmcc.2014.11.003 |
0.4 |
|
| 2014 |
Saccone V, Consalvi S, Giordani L, Mozzetta C, Barozzi I, Sandoná M, Ryan T, Rojas-Muñoz A, Madaro L, Fasanaro P, Borsellino G, De Bardi M, Frigè G, Termanini A, Sun X, ... ... Mercola M, et al. HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles. Genes & Development. 28: 841-57. PMID 24682306 DOI: 10.1101/Gad.234468.113 |
0.311 |
|
| 2014 |
Wahlquist C, Jeong D, Rojas-Muñoz A, Kho C, Lee A, Mitsuyama S, van Mil A, Park WJ, Sluijter JP, Doevendans PA, Hajjar RJ, Mercola M. Inhibition of miR-25 improves cardiac contractility in the failing heart. Nature. 508: 531-5. PMID 24670661 DOI: 10.1038/Nature13073 |
0.327 |
|
| 2014 |
Willems E, Mercola M. Reprogramming the cardiac field. Circulation Research. 114: 409-11. PMID 24481840 DOI: 10.1161/Circresaha.113.302946 |
0.416 |
|
| 2014 |
Savtchenko A, Ruidiaz M, Miller EW, McKeithan W, Heynen-Genel S, Mercola M. Multiparametric One-Color Assays for Functional Assessment of Cardiomyocytes Biophysical Journal. 106: 720a. DOI: 10.1016/J.Bpj.2013.11.3980 |
0.361 |
|
| 2013 |
Cai W, Albini S, Wei K, Willems E, Guzzo RM, Tsuda M, Giordani L, Spiering S, Kurian L, Yeo GW, Puri PL, Mercola M. Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment. Genes & Development. 27: 2332-44. PMID 24186978 DOI: 10.1101/Gad.225144.113 |
0.798 |
|
| 2013 |
Willems E, Mercola M. Jumonji and cardiac fate. Circulation Research. 113: 837-9. PMID 24030015 DOI: 10.1161/Circresaha.113.302202 |
0.368 |
|
| 2013 |
Bhargava V, Ko P, Willems E, Mercola M, Subramaniam S. Quantitative transcriptomics using designed primer-based amplification. Scientific Reports. 3: 1740. PMID 23624976 DOI: 10.1038/Srep01740 |
0.35 |
|
| 2013 |
Mercola M, Colas A, Willems E. Induced pluripotent stem cells in cardiovascular drug discovery. Circulation Research. 112: 534-48. PMID 23371902 DOI: 10.1161/Circresaha.111.250266 |
0.74 |
|
| 2013 |
Whittaker R, Cerignoli F, Ingermanson R, Towart R, Gallacher DJ, Mercola M, Price J. Simultaneous recording of action potentials and calcium transients from stem cell-derived cardiomyocytes: Applications for cardiotoxicity testing Journal of Pharmacological and Toxicological Methods. 68: e47. DOI: 10.1016/J.Vascn.2013.01.170 |
0.313 |
|
| 2012 |
Mercola M. Cardiovascular biology: A boost for heart regeneration. Nature. 492: 360-2. PMID 23222522 DOI: 10.1038/Nature11763 |
0.346 |
|
| 2012 |
Puri PL, Mercola M. BAF60 A, B, and Cs of muscle determination and renewal. Genes & Development. 26: 2673-83. PMID 23222103 DOI: 10.1101/Gad.207415.112 |
0.345 |
|
| 2012 |
McKeithan WL, Colas AR, Bushway PJ, Ray S, Mercola M. Serum-free generation of multipotent mesoderm (Kdr+) progenitor cells in mouse embryonic stem cells for functional genomics screening. Current Protocols in Stem Cell Biology. Unit 1F.13. PMID 23154934 DOI: 10.1002/9780470151808.Sc01F13S23 |
0.755 |
|
| 2012 |
Colas AR, McKeithan WL, Cunningham TJ, Bushway PJ, Garmire LX, Duester G, Subramaniam S, Mercola M. Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis. Genes & Development. 26: 2567-79. PMID 23152446 DOI: 10.1101/Gad.200758.112 |
0.729 |
|
| 2012 |
Schade D, Lanier M, Willems E, Okolotowicz K, Bushway P, Wahlquist C, Gilley C, Mercola M, Cashman JR. Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signaling. Journal of Medicinal Chemistry. 55: 9946-57. PMID 23130626 DOI: 10.1021/Jm301144G |
0.355 |
|
| 2012 |
Ruiz S, Diep D, Gore A, Panopoulos AD, Montserrat N, Plongthongkum N, Kumar S, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Kan NG, Schöler HR, Mercola M, et al. Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 16196-201. PMID 22991473 DOI: 10.1073/Pnas.1202352109 |
0.379 |
|
| 2012 |
Cerignoli F, Charlot D, Whittaker R, Ingermanson R, Gehalot P, Savchenko A, Gallacher DJ, Towart R, Price JH, McDonough PM, Mercola M. High throughput measurement of Ca²⺠dynamics for drug risk assessment in human stem cell-derived cardiomyocytes by kinetic image cytometry. Journal of Pharmacological and Toxicological Methods. 66: 246-56. PMID 22926323 DOI: 10.1016/J.Vascn.2012.08.167 |
0.354 |
|
| 2012 |
Cai W, Guzzo RM, Wei K, Willems E, Davidovics H, Mercola M. A Nodal-to-TGFβ cascade exerts biphasic control over cardiopoiesis. Circulation Research. 111: 876-81. PMID 22872153 DOI: 10.1161/Circresaha.112.270272 |
0.786 |
|
| 2012 |
Willems E, Cabral-Teixeira J, Schade D, Cai W, Reeves P, Bushway PJ, Lanier M, Walsh C, Kirchhausen T, Izpisua Belmonte JC, Cashman J, Mercola M. Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 11: 242-52. PMID 22862949 DOI: 10.1016/J.Stem.2012.04.025 |
0.435 |
|
| 2012 |
Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, ... ... Mercola M, et al. HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chemistry & Biology. 19: 806-18. PMID 22840769 DOI: 10.1016/J.Chembiol.2012.05.014 |
0.323 |
|
| 2012 |
Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima RG, Willerson JT, Potaman VN, Schwartz RJ. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proceedings of the National Academy of Sciences of the United States of America. 109: 13016-21. PMID 22826236 DOI: 10.1073/Pnas.1120299109 |
0.424 |
|
| 2012 |
Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, ... ... Mercola M, et al. APJ acts as a dual receptor in cardiac hypertrophy. Nature. 488: 394-8. PMID 22810587 DOI: 10.1038/Nature11263 |
0.581 |
|
| 2012 |
Forte E, Miraldi F, Chimenti I, Angelini F, Zeuner A, Giacomello A, Mercola M, Messina E. TGFβ-dependent epithelial-to-mesenchymal transition is required to generate cardiospheres from human adult heart biopsies. Stem Cells and Development. 21: 3081-90. PMID 22765842 DOI: 10.1089/Scd.2012.0277 |
0.433 |
|
| 2012 |
Hohenstein Elliott KA, Peterson C, Soundararajan A, Kan N, Nelson B, Spiering S, Mercola M, Bright GR. Laser-Based Propagation of Human iPS and ES Cells Generates Reproducible Cultures with Enhanced Differentiation Potential. Stem Cells International. 2012: 926463. PMID 22701128 DOI: 10.1155/2012/926463 |
0.355 |
|
| 2012 |
Lanier M, Schade D, Willems E, Tsuda M, Spiering S, Kalisiak J, Mercola M, Cashman JR. Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure-activity relationship study based on inhibitors for the Wnt response. Journal of Medicinal Chemistry. 55: 697-708. PMID 22191557 DOI: 10.1021/Jm2010223 |
0.395 |
|
| 2012 |
Mercola M, Doevendans P. Meeting review: cardiomyocyte regeneration and protection, La Jolla, California, June 2011. Journal of Cardiovascular Translational Research. 5: 100-5. PMID 22057688 DOI: 10.1007/S12265-011-9323-X |
0.393 |
|
| 2012 |
Schneider JW, Mercola M. Chemical genetics of cardiac regeneration Muscle. 1: 707-720. DOI: 10.1016/B978-0-12-381510-1.00049-1 |
0.363 |
|
| 2011 |
Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, Cashman J, Mercola M. Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. Circulation Research. 109: 360-4. PMID 21737789 DOI: 10.1161/Circresaha.111.249540 |
0.458 |
|
| 2011 |
Prigozhina NL, Heisel A, Wei K, Noberini R, Hunter EA, Calzolari D, Seldeen JR, Pasquale EB, Ruiz-Lozano P, Mercola M, Price JH. Characterization of a novel angiogenic model based on stable, fluorescently labelled endothelial cell lines amenable to scale-up for high content screening. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 103: 467-81. PMID 21732911 DOI: 10.1042/Bc20100146 |
0.561 |
|
| 2011 |
Willems E, Lanier M, Forte E, Lo F, Cashman J, Mercola M. A chemical biology approach to myocardial regeneration. Journal of Cardiovascular Translational Research. 4: 340-50. PMID 21424858 DOI: 10.1007/S12265-011-9270-6 |
0.423 |
|
| 2011 |
Willems E, Mercola M. What your heart doth know. Cell Stem Cell. 8: 124-6. PMID 21295266 DOI: 10.1016/J.Stem.2011.01.003 |
0.368 |
|
| 2011 |
Savtchenko A, Wei K, Cerignoli F, Price J, Mercola M. Kinetic Imaging Cytometry of Stem Cell-Derived Cardiomyocytes Paced by Electrical Field Stimulation Biophysical Journal. 100: 318a. DOI: 10.1016/J.Bpj.2010.12.1935 |
0.358 |
|
| 2010 |
Kiselyuk A, Farber-Katz S, Cohen T, Lee SH, Geron I, Azimi B, Heynen-Genel S, Singer O, Price J, Mercola M, Itkin-Ansari P, Levine F. Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen. Journal of Biomolecular Screening. 15: 663-70. PMID 20547533 DOI: 10.1177/1087057110372257 |
0.337 |
|
| 2010 |
Salomonis N, Schlieve CR, Pereira L, Wahlquist C, Colas A, Zambon AC, Vranizan K, Spindler MJ, Pico AR, Cline MS, Clark TA, Williams A, Blume JE, Samal E, Mercola M, et al. Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 107: 10514-9. PMID 20498046 DOI: 10.1073/Pnas.0912260107 |
0.768 |
|
| 2010 |
Jacot JG, Kita-Matsuo H, Wei KA, Chen HS, Omens JH, Mercola M, McCulloch AD. Cardiac myocyte force development during differentiation and maturation. Annals of the New York Academy of Sciences. 1188: 121-7. PMID 20201894 DOI: 10.1111/J.1749-6632.2009.05091.X |
0.395 |
|
| 2010 |
Kim C, Majdi M, Xia P, Wei KA, Talantova M, Spiering S, Nelson B, Mercola M, Chen HS. Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation. Stem Cells and Development. 19: 783-95. PMID 20001453 DOI: 10.1089/Scd.2009.0349 |
0.398 |
|
| 2010 |
Heisel A, Wei K, Hunter EA, Ruiz-Lozano P, Mercola M, Price JH, Prigozhina NL. Developing new angiogenic models based on a novel, stable, fluorescently labeled endothelial cell line F1000research. 1. DOI: 10.7490/F1000Research.102.1 |
0.517 |
|
| 2010 |
Katkov II, Nelson B, Mercola M. 46. Cryopreservation of human pluripotent stem cells: Basic cryobiology and practical implications Cryobiology. 61: 375-376. DOI: 10.1016/J.Cryobiol.2010.10.050 |
0.328 |
|
| 2010 |
Mercola M, Guzzo RM, Foley AC. Cardiac Development in the Frog Heart Development and Regeneration. 87-102. DOI: 10.1016/B978-0-12-381332-9.00003-7 |
0.763 |
|
| 2009 |
Chen HS, Kim C, Mercola M. Electrophysiological challenges of cell-based myocardial repair. Circulation. 120: 2496-508. PMID 20008740 DOI: 10.1161/Circulationaha.107.751412 |
0.34 |
|
| 2009 |
Salomonis N, Nelson B, Vranizan K, Pico AR, Hanspers K, Kuchinsky A, Ta L, Mercola M, Conklin BR. Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors. Plos Computational Biology. 5: e1000553. PMID 19893621 DOI: 10.1371/Journal.Pcbi.1000553 |
0.459 |
|
| 2009 |
Kita-Matsuo H, Barcova M, Prigozhina N, Salomonis N, Wei K, Jacot JG, Nelson B, Spiering S, Haverslag R, Kim C, Talantova M, Bajpai R, Calzolari D, Terskikh A, McCulloch AD, ... ... Mercola M, et al. Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. Plos One. 4: e5046. PMID 19352491 DOI: 10.1371/Journal.Pone.0005046 |
0.375 |
|
| 2009 |
Willems E, Bushway PJ, Mercola M. Natural and synthetic regulators of embryonic stem cell cardiogenesis. Pediatric Cardiology. 30: 635-42. PMID 19319460 DOI: 10.1007/S00246-009-9409-2 |
0.438 |
|
| 2009 |
Princen F, Bard E, Sheikh F, Zhang SS, Wang J, Zago WM, Wu D, Trelles RD, Bailly-Maitre B, Kahn CR, Chen Y, Reed JC, Tong GG, Mercola M, Chen J, et al. Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death. Molecular and Cellular Biology. 29: 378-88. PMID 19001090 DOI: 10.1128/Mcb.01661-08 |
0.302 |
|
| 2008 |
Maurer J, Nelson B, Ceceña G, Bajpai R, Mercola M, Terskikh A, Oshima RG. Contrasting expression of keratins in mouse and human embryonic stem cells. Plos One. 3: e3451. PMID 18941637 DOI: 10.1371/Journal.Pone.0003451 |
0.368 |
|
| 2008 |
Korol O, Gupta RW, Mercola M. A novel activity of the Dickkopf-1 amino terminal domain promotes axial and heart development independently of canonical Wnt inhibition. Developmental Biology. 324: 131-8. PMID 18840423 DOI: 10.1016/J.Ydbio.2008.09.012 |
0.404 |
|
| 2008 |
Campa VM, Gutiérrez-Lanza R, Cerignoli F, Díaz-Trelles R, Nelson B, Tsuji T, Barcova M, Jiang W, Mercola M. Notch activates cell cycle reentry and progression in quiescent cardiomyocytes. The Journal of Cell Biology. 183: 129-41. PMID 18838555 DOI: 10.1083/Jcb.200806104 |
0.418 |
|
| 2008 |
Bushway PJ, Mercola M, Price JH. A comparative analysis of standard microtiter plate reading versus imaging in cellular assays. Assay and Drug Development Technologies. 6: 557-67. PMID 18795873 DOI: 10.1089/Adt.2008.139 |
0.306 |
|
| 2008 |
Mercola M. Natural and small molecule regulators of stem cell cardiomyocyte differentiation Journal of Molecular and Cellular Cardiology. 44: 435. DOI: 10.1016/J.Yjmcc.2007.07.006 |
0.379 |
|
| 2007 |
Mercola M. Chemical probes of neural stem cell self-renewal. Nature Chemical Biology. 3: 246-7. PMID 17438546 DOI: 10.1038/Nchembio0507-246 |
0.336 |
|
| 2007 |
Foley AC, Korol O, Timmer AM, Mercola M. Multiple functions of Cerberus cooperate to induce heart downstream of Nodal. Developmental Biology. 303: 57-65. PMID 17123501 DOI: 10.1016/J.Ydbio.2006.10.033 |
0.751 |
|
| 2007 |
Guzzo RM, Foley AC, Ibarra YM, Mercola M. Signaling Pathways in Embryonic Heart Induction Advances in Developmental Biology. 18: 117-151. DOI: 10.1016/S1574-3349(07)18005-4 |
0.781 |
|
| 2007 |
Foley AC, Lakaduc AC, Mercola M. WITHDRAWN: Dkk-1 and Nodal function in parallel to induce both heart and endodermal organs such as liver and pancreas Developmental Biology. 306: 416-417. DOI: 10.1016/J.Ydbio.2007.03.295 |
0.675 |
|
| 2006 |
Foley AC, Gupta RW, Guzzo RM, Korol O, Mercola M. Embryonic heart induction. Annals of the New York Academy of Sciences. 1080: 85-96. PMID 17132777 DOI: 10.1196/Annals.1380.008 |
0.81 |
|
| 2006 |
Bushway PJ, Mercola M. High-throughput screening for modulators of stem cell differentiation. Methods in Enzymology. 414: 300-16. PMID 17110199 DOI: 10.1016/S0076-6879(06)14017-3 |
0.389 |
|
| 2006 |
Rutenberg JB, Fischer A, Jia H, Gessler M, Zhong TP, Mercola M. Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors. Development (Cambridge, England). 133: 4381-90. PMID 17021042 DOI: 10.1242/Dev.02607 |
0.418 |
|
| 2006 |
Hao E, Tyrberg B, Itkin-Ansari P, Lakey JR, Geron I, Monosov EZ, Barcova M, Mercola M, Levine F. Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nature Medicine. 12: 310-6. PMID 16491084 DOI: 10.1038/Nm1367 |
0.363 |
|
| 2005 |
Foley AC, Mercola M. Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex. Genes & Development. 19: 387-96. PMID 15687261 DOI: 10.1101/Gad.1279405 |
0.753 |
|
| 2005 |
Hernandez-Lagunas L, Choi IF, Kaji T, Simpson P, Hershey C, Zhou Y, Zon L, Mercola M, Artinger KB. Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification. Developmental Biology. 278: 347-57. PMID 15680355 DOI: 10.1016/J.Ydbio.2004.11.014 |
0.645 |
|
| 2004 |
Wei ZL, Petukhov PA, Bizik F, Teixeira JC, Mercola M, Volpe EA, Glazer RI, Willson TM, Kozikowski AP. Isoxazolyl-serine-based agonists of peroxisome proliferator-activated receptor: design, synthesis, and effects on cardiomyocyte differentiation. Journal of the American Chemical Society. 126: 16714-5. PMID 15612696 DOI: 10.1021/Ja046386L |
0.32 |
|
| 2004 |
Levine F, Mercola M. No pancreatic endocrine stem cells? The New England Journal of Medicine. 351: 1024-6. PMID 15342812 DOI: 10.1056/Nejmcibr041779 |
0.318 |
|
| 2004 |
Foley A, Mercola M. Heart induction: embryology to cardiomyocyte regeneration. Trends in Cardiovascular Medicine. 14: 121-5. PMID 15121161 DOI: 10.1016/J.Tcm.2004.01.003 |
0.749 |
|
| 2003 |
Mercola M. Left-right asymmetry: nodal points. Journal of Cell Science. 116: 3251-7. PMID 12857784 DOI: 10.1242/Jcs.00668 |
0.336 |
|
| 2003 |
Woda JM, Pastagia J, Mercola M, Artinger KB. Dlx proteins position the neural plate border and determine adjacent cell fates. Development (Cambridge, England). 130: 331-42. PMID 12466200 DOI: 10.1242/Dev.00212 |
0.672 |
|
| 2002 |
Rones MS, Woda J, Mercola M, McLaughlin KA. Isolation and characterization of Xenopus Hey-1: a downstream mediator of Notch signaling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 225: 554-60. PMID 12454931 DOI: 10.1002/Dvdy.10192 |
0.617 |
|
| 2002 |
Levin M, Thorlin T, Robinson KR, Nogi T, Mercola M. Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning. Cell. 111: 77-89. PMID 12372302 DOI: 10.1016/S0092-8674(02)00939-X |
0.401 |
|
| 2002 |
Roberson DW, Alosi JA, Mercola M, Cotanche DA. REST mRNA expression in normal and regenerating avian auditory epithelium. Hearing Research. 172: 62-72. PMID 12361867 DOI: 10.1016/S0378-5955(02)00512-9 |
0.35 |
|
| 2001 |
Mercola M, Levin M. Left-right asymmetry determination in vertebrates. Annual Review of Cell and Developmental Biology. 17: 779-805. PMID 11687504 DOI: 10.1146/Annurev.Cellbio.17.1.779 |
0.386 |
|
| 2001 |
Schneider VA, Mercola M. Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes & Development. 15: 304-15. PMID 11159911 DOI: 10.1101/Gad.855601 |
0.442 |
|
| 2000 |
McLaughlin KA, Rones MS, Mercola M. Notch regulates cell fate in the developing pronephros. Developmental Biology. 227: 567-80. PMID 11071775 DOI: 10.1006/Dbio.2000.9913 |
0.643 |
|
| 2000 |
Levin M, Mercola M. Expression of connexin 30 in Xenopus embryos and its involvement in hatching gland function. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 219: 96-101. PMID 10974676 DOI: 10.1002/1097-0177(200009)219:1<96::Aid-Dvdy1034>3.0.Co;2-0 |
0.473 |
|
| 2000 |
Raffin M, Leong LM, Rones MS, Sparrow D, Mohun T, Mercola M. Subdivision of the cardiac Nkx2.5 expression domain into myogenic and nonmyogenic compartments. Developmental Biology. 218: 326-40. PMID 10656773 DOI: 10.1006/Dbio.1999.9579 |
0.409 |
|
| 1999 |
Zhu L, Marvin MJ, Gardiner A, Lassar AB, Mercola M, Stern CD, Levin M. Cerberus regulates left-right asymmetry of the embryonic head and heart. Current Biology : Cb. 9: 931-8. PMID 10508582 DOI: 10.1016/S0960-9822(99)80419-9 |
0.706 |
|
| 1999 |
Schneider VA, Mercola M. Spatially distinct head and heart inducers within the Xenopus organizer region. Current Biology : Cb. 9: 800-9. PMID 10469564 DOI: 10.1016/S0960-9822(99)80363-7 |
0.372 |
|
| 1999 |
Mercola M. Embryological basis for cardiac left-right asymmetry. Seminars in Cell & Developmental Biology. 10: 109-16. PMID 10355035 DOI: 10.1006/Scdb.1998.0280 |
0.354 |
|
| 1998 |
Levin M, Mercola M. Evolutionary conservation of mechanisms upstream of asymmetric Nodal expression: reconciling chick and Xenopus. Developmental Genetics. 23: 185-93. PMID 9842713 DOI: 10.1002/(Sici)1520-6408(1998)23:3<185::Aid-Dvg4>3.0.Co;2-1 |
0.464 |
|
| 1998 |
Levin M, Mercola M. Gap junctions are involved in the early generation of left-right asymmetry. Developmental Biology. 203: 90-105. PMID 9806775 DOI: 10.1006/Dbio.1998.9024 |
0.471 |
|
| 1998 |
Levin M, Mercola M. The compulsion of chirality: toward an understanding of left-right asymmetry. Genes & Development. 12: 763-9. PMID 9512510 DOI: 10.1101/Gad.12.6.763 |
0.424 |
|
| 1998 |
Yang J, Symes K, Mercola M, Schreiber SL. Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment. Current Biology : Cb. 8: 11-8. PMID 9427627 DOI: 10.1016/S0960-9822(98)70015-6 |
0.745 |
|
| 1997 |
Nascone N, Mercola M. Organizer induction determines left-right asymmetry in Xenopus. Developmental Biology. 189: 68-78. PMID 9281338 DOI: 10.1006/Dbio.1997.8635 |
0.347 |
|
| 1997 |
Payne J, Shibasaki F, Mercola M. Spina bifida occulta in homozygous Patch mouse embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 209: 105-16. PMID 9142500 DOI: 10.1002/(Sici)1097-0177(199705)209:1<105::Aid-Aja10>3.0.Co;2-0 |
0.32 |
|
| 1997 |
Ataliotis P, Mercola M. Distribution and functions of platelet-derived growth factors and their receptors during embryogenesis. International Review of Cytology. 172: 95-127. PMID 9102395 DOI: 10.1016/S0074-7696(08)62359-1 |
0.783 |
|
| 1996 |
Nascone N, Mercola M. Endoderm and cardiogenesis new insights. Trends in Cardiovascular Medicine. 6: 211-6. PMID 21232299 DOI: 10.1016/S1050-1738(96)00086-2 |
0.408 |
|
| 1996 |
Dunn MK, Mercola M. Cloning and expression of Xenopus CCT gamma, a chaperonin subunit developmentally regulated in neural-derived and myogenic lineages. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 205: 387-94. PMID 8901050 DOI: 10.1002/(Sici)1097-0177(199604)205:4<387::Aid-Aja3>3.0.Co;2-E |
0.352 |
|
| 1996 |
Symes K, Mercola M. Embryonic mesoderm cells spread in response to platelet-derived growth factor and signaling by phosphatidylinositol 3-kinase. Proceedings of the National Academy of Sciences of the United States of America. 93: 9641-4. PMID 8790383 DOI: 10.1073/Pnas.93.18.9641 |
0.416 |
|
| 1995 |
Dunn MK, Mercola M, Moore DD. Cyclopamine, a steroidal alkaloid, disrupts development of cranial neural crest cells in Xenopus. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 202: 255-70. PMID 7780175 DOI: 10.1002/Aja.1002020305 |
0.363 |
|
| 1994 |
Ho L, Mercola M, Gudas LJ. Xenopus laevis cellular retinoic acid-binding protein: temporal and spatial expression pattern during early embryogenesis. Mechanisms of Development. 47: 53-64. PMID 7947321 DOI: 10.1016/0925-4773(94)90095-7 |
0.307 |
|
| 1994 |
Ho L, Symes K, Yordán C, Gudas LJ, Mercola M. Localization of PDGF A and PDGFR alpha mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells. Mechanisms of Development. 48: 165-74. PMID 7893600 DOI: 10.1016/0925-4773(94)90057-4 |
0.741 |
|
| 1993 |
Jones SD, Ho L, Smith JC, Yordan C, Stiles CD, Mercola M. The Xenopus platelet-derived growth factor alpha receptor: cDNA cloning and demonstration that mesoderm induction establishes the lineage-specific pattern of ligand and receptor gene expression. Developmental Genetics. 14: 185-93. PMID 8358864 DOI: 10.1002/Dvg.1020140305 |
0.582 |
|
| 1992 |
Palmieri SL, Payne J, Stiles CD, Biggers JD, Mercola M. Expression of mouse PDGF-A and PDGF alpha-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action. Mechanisms of Development. 39: 181-91. PMID 1292572 DOI: 10.1016/0925-4773(92)90045-L |
0.567 |
|
| 1991 |
Stephenson DA, Mercola M, Anderson E, Wang CY, Stiles CD, Bowen-Pope DF, Chapman VM. Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation. Proceedings of the National Academy of Sciences of the United States of America. 88: 6-10. PMID 1846043 DOI: 10.1073/Pnas.88.1.6 |
0.538 |
|
| 1990 |
Mercola M, Deininger PL, Shamah SM, Porter J, Wang CY, Stiles CD. Dominant-negative mutants of a platelet-derived growth factor gene. Genes & Development. 4: 2333-41. PMID 2279701 DOI: 10.1101/Gad.4.12B.2333 |
0.565 |
|
| 1990 |
Mercola M, Wang CY, Kelly J, Brownlee C, Jackson-Grusby L, Stiles C, Bowen-Pope D. Selective expression of PDGF A and its receptor during early mouse embryogenesis. Developmental Biology. 138: 114-22. PMID 2155144 DOI: 10.1016/0012-1606(90)90181-H |
0.582 |
|
| 1988 |
Mercola M, Melton DA, Stiles CD. Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos. Science (New York, N.Y.). 241: 1223-5. PMID 3413486 DOI: 10.1126/Science.3413486 |
0.558 |
|
| 1988 |
Kakkis E, Mercola M, Calame K. Strong transcriptional activation of translocated c-myc genes occurs without a strong nearby enhancer or promoter. Nucleic Acids Research. 16: 77-96. PMID 2829126 DOI: 10.1093/Nar/16.1.77 |
0.569 |
|
| 1987 |
Cochran BH, Zumstein P, Zullo J, Rollins B, Mercola M, Stiles CD. Differential colony hybridization: molecular cloning from a zero data base. Methods in Enzymology. 147: 64-85. PMID 2444861 DOI: 10.1016/0076-6879(87)47099-7 |
0.734 |
|
| 1985 |
Mercola M, Goverman J, Mirell C, Calame K. Immunoglobulin heavy-chain enhancer requires one or more tissue-specific factors. Science (New York, N.Y.). 227: 266-70. PMID 3917575 DOI: 10.1126/Science.3917575 |
0.596 |
|
| 1984 |
Prehn J, Mercola M, Calame K. Translocation affects normal c-myc promoter usage and activates fifteen cryptic c-myc transcription starts in plasmacytoma M603. Nucleic Acids Research. 12: 8987-9007. PMID 6096815 DOI: 10.1093/Nar/12.23.8987 |
0.557 |
|
| 1984 |
Prehn J, Mercola M, Calame K. Trasiocation affects normal c-myc promoter usage and activates fifteen cryptic c-myc transcription starts in plasmacytoma M603 Nucleic Acids Research. 12: 8987-9007. DOI: 10.1093/nar/12.23.8987 |
0.506 |
|
| 1983 |
Mercola M, Wang XF, Olsen J, Calame K. Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus Science. 221: 663-665. PMID 6306772 DOI: 10.1126/Science.6306772 |
0.565 |
|
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