Year |
Citation |
Score |
2023 |
Naguib S, Backstrom JR, Artis E, Ghose P, Stahl A, Hardin R, Haider AA, Ang J, Calkins DJ, Rex TS. NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells. Acta Neuropathologica Communications. 11: 171. PMID 37875948 DOI: 10.1186/s40478-023-01663-1 |
0.417 |
|
2022 |
Haider AA, Rex TS, Wareham LK. cGMP Signaling in the Neurovascular Unit-Implications for Retinal Ganglion Cell Survival in Glaucoma. Biomolecules. 12. PMID 36421684 DOI: 10.3390/biom12111671 |
0.361 |
|
2022 |
Holden JM, Al Hussein Al Awamlh S, Croteau LP, Boal AM, Rex TS, Risner ML, Calkins DJ, Wareham LK. Dysfunctional cGMP Signaling Leads to Age-Related Retinal Vascular Alterations and Astrocyte Remodeling in Mice. International Journal of Molecular Sciences. 23. PMID 35328488 DOI: 10.3390/ijms23063066 |
0.394 |
|
2021 |
Thomas CN, Bernardo-Colón A, Courtie E, Essex G, Rex TS, Blanch RJ, Ahmed Z. Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma. Scientific Reports. 11: 16839. PMID 34413361 DOI: 10.1038/s41598-021-96107-y |
0.383 |
|
2021 |
Naguib S, Backstrom JR, Gil M, Calkins DJ, Rex TS. Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension. Redox Biology. 101883. PMID 33579667 DOI: 10.1016/j.redox.2021.101883 |
0.354 |
|
2020 |
Backstrom JR, Sheng J, Wang MC, Bernardo-Colón A, Rex TS. Optimization of dCas9 and CRISPRi Elements for a Single Adeno-Associated Virus that Targets an Endogenous Gene. Molecular Therapy. Methods & Clinical Development. 19: 139-148. PMID 33024795 DOI: 10.1016/J.Omtm.2020.09.001 |
0.351 |
|
2020 |
Elenberger J, Kim B, de Castro-Abeger A, Rex TS. Connections between intrinsically photosensitive retinal ganglion cells and TBI symptomology. Neurology. PMID 32934170 DOI: 10.1212/Wnl.0000000000010830 |
0.354 |
|
2020 |
Thomas CN, Courtie E, Bernardo-Colón A, Essex G, Rex TS, Ahmed Z, Blanch RJ. Assessment of necroptosis in the retina in a repeated primary ocular blast injury mouse model. Experimental Eye Research. 108102. PMID 32522477 DOI: 10.1016/J.Exer.2020.108102 |
0.482 |
|
2019 |
Naguib S, Bernardo-Colón A, Cencer C, Gandra N, Rex TS. Galantamine protects against synaptic, axonal, and vision deficits in experimental neurotrauma. Neurobiology of Disease. 104695. PMID 31778813 DOI: 10.1016/J.Nbd.2019.104695 |
0.396 |
|
2019 |
Bernardo-Colón A, Vest V, Cooper ML, Naguib SA, Calkins DJ, Rex TS. Progression and Pathology of Traumatic Optic Neuropathy From Repeated Primary Blast Exposure. Frontiers in Neuroscience. 13: 719. PMID 31354422 DOI: 10.3389/Fnins.2019.00719 |
0.384 |
|
2019 |
Backstrom JR, Sheng J, Fischer RA, Sappington RM, Rex TS. Phenotypes of primary retinal macroglia: Implications for purification and culture conditions. Experimental Eye Research. 182: 85-92. PMID 30902621 DOI: 10.1016/J.Exer.2019.03.008 |
0.494 |
|
2018 |
Vest V, Bernardo-Colon A, Watkins D, Kim B, Rex TS. Rapid repeat exposure to sub-threshold trauma causes synergistic axonal damage and functional deficits in the visual pathway in a mouse model. Journal of Neurotrauma. PMID 30451083 DOI: 10.1089/Neu.2018.6046 |
0.328 |
|
2018 |
Bernardo-Colon A, Vest V, Clark A, Cooper ML, Calkins DJ, Harrison FE, Rex TS. Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma. Cell Death & Disease. 9: 1097. PMID 30367086 DOI: 10.1038/S41419-018-1061-4 |
0.356 |
|
2016 |
Bond WS, Hines-Beard J, GoldenMerry YL, Davis M, Farooque A, Sappington RM, Calkins DJ, Rex TS. Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 230-239. PMID 28135578 DOI: 10.1038/mt.2015.198 |
0.473 |
|
2016 |
Bricker-Anthony C, Rex TS. Correction: Neurodegeneration and Vision Loss after Mild Blunt Trauma in the C57Bl/6 and DBA/2J Mouse. Plos One. 11: e0165872. PMID 27788271 DOI: 10.1371/Journal.Pone.0165872 |
0.322 |
|
2016 |
Bricker-Anthony C, Hines-Beard J, D'Surney L, Rex TS. Erratum to: Exacerbation of blast-induced ocular trauma by an immune response. Journal of Neuroinflammation. 13: 220. PMID 27576346 DOI: 10.1186/S12974-016-0704-6 |
0.319 |
|
2016 |
Rex TS, Kasmala L, Bond WS, de Lucas Cerrillo AM, Wynn K, Lewin AS. Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa. Plos One. 11: e0157411. PMID 27299810 DOI: 10.1371/Journal.Pone.0157411 |
0.6 |
|
2016 |
Bricker-Anthony C, D'Surney L, Lunn B, Hines-Beard J, Jo M, Bernardo-Colon A, Rex TS. Erythropoietin either Prevents or Exacerbates Retinal Damage from Eye Trauma Depending on Treatment Timing. Optometry and Vision Science : Official Publication of the American Academy of Optometry. PMID 27281679 DOI: 10.1097/Opx.0000000000000898 |
0.372 |
|
2016 |
Bricker-Anthony C, Hines-Beard J, Rex TS. Eye-Directed Overpressure Airwave-Induced Trauma Causes Lasting Damage to the Anterior and Posterior Globe: A Model for Testing Cell-Based Therapies. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 26982447 DOI: 10.1089/Jop.2015.0104 |
0.506 |
|
2016 |
Hines-Beard J, Bond WS, Backstrom JR, Rex TS. Virus-mediated EpoR76E gene therapy preserves vision in a glaucoma model by modulating neuroinflammation and decreasing oxidative stress. Journal of Neuroinflammation. 13: 39. PMID 26876380 DOI: 10.1186/S12974-016-0499-5 |
0.5 |
|
2015 |
Bond WS, Hines-Beard JB, GoldenMerry YL, Davis M, Farooque A, Sappington RM, Calkins DJ, Rex TS. Virus-mediated EpoR76E therapy slows optic nerve axonopathy in experimental glaucoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26502777 DOI: 10.1038/Mt.2015.198 |
0.554 |
|
2015 |
Rex TS. Gene therapy to treat inherited and complex retinal degenerative diseases. Molecular Therapy. Methods & Clinical Development. 2: 15027. PMID 26251841 DOI: 10.1038/Mtm.2015.27 |
0.634 |
|
2015 |
Bricker-Anthony C, Rex TS. Neurodegeneration and Vision Loss after Mild Blunt Trauma in the C57Bl/6 and DBA/2J Mouse. Plos One. 10: e0131921. PMID 26148200 DOI: 10.1371/Journal.Pone.0131921 |
0.41 |
|
2015 |
Rex TS, Reilly MA, Sponsel WE. Elucidating the effects of primary blast on the eye. Clinical & Experimental Ophthalmology. 43: 197-9. PMID 25923380 DOI: 10.1111/Ceo.12502 |
0.312 |
|
2015 |
de Lucas Cerrillo AM, Bond WS, Rex TS. Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin. Gene Therapy. 22: 365-73. PMID 25716531 DOI: 10.1038/Gt.2015.12 |
0.579 |
|
2015 |
Bond WS, Chang YL, Davis MN, Sappington RM, Rex TS. 204. Treatment with Modified Erythropoietin Gene Therapy Is Neuroprotective in a Mouse Model of Induced Ocular Hypertension Molecular Therapy. 23: S81. DOI: 10.1016/S1525-0016(16)33809-6 |
0.436 |
|
2014 |
Rex TS. Delayed vision loss and therapeutic intervention after blast injury. Investigative Ophthalmology & Visual Science. 55: 8342. PMID 25525189 DOI: 10.1167/Iovs.14-16135 |
0.472 |
|
2014 |
Bricker-Anthony C, Hines-Beard J, D'Surney L, Rex TS. Exacerbation of blast-induced ocular trauma by an immune response. Journal of Neuroinflammation. 11: 192. PMID 25472427 DOI: 10.1186/S12974-014-0192-5 |
0.442 |
|
2014 |
Bond WS, Rex TS. Evidence That Erythropoietin Modulates Neuroinflammation through Differential Action on Neurons, Astrocytes, and Microglia. Frontiers in Immunology. 5: 523. PMID 25374571 DOI: 10.3389/Fimmu.2014.00523 |
0.316 |
|
2014 |
Bricker-Anthony C, Hines-Beard J, Rex TS. Molecular changes and vision loss in a mouse model of closed-globe blast trauma. Investigative Ophthalmology & Visual Science. 55: 4853-62. PMID 24994864 DOI: 10.1167/Iovs.14-14353 |
0.554 |
|
2013 |
Hines-Beard J, Desai S, Haag R, Esumi N, D'Surney L, Parker S, Richardson C, Rex TS. Identification of a therapeutic dose of continuously delivered erythropoietin in the eye using an inducible promoter system. Current Gene Therapy. 13: 275-81. PMID 23773177 DOI: 10.2174/15665232113139990024 |
0.495 |
|
2013 |
Templeton JP, Freeman NE, Nickerson JM, Jablonski MM, Rex TS, Williams RW, Geisert EE. Innate immune network in the retina activated by optic nerve crush. Investigative Ophthalmology & Visual Science. 54: 2599-606. PMID 23493296 DOI: 10.1167/Iovs.12-11175 |
0.389 |
|
2013 |
Dhanushkodi A, Akano EO, Roguski EE, Xue Y, Rao SK, Matta SG, Rex TS, McDonald MP. A single intramuscular injection of rAAV-mediated mutant erythropoietin protects against MPTP-induced parkinsonism. Genes, Brain, and Behavior. 12: 224-33. PMID 23190369 DOI: 10.1111/Gbb.12001 |
0.354 |
|
2012 |
Hines-Beard J, Marchetta J, Gordon S, Chaum E, Geisert EE, Rex TS. A mouse model of ocular blast injury that induces closed globe anterior and posterior pole damage. Experimental Eye Research. 99: 63-70. PMID 22504073 DOI: 10.1016/J.Exer.2012.03.013 |
0.378 |
|
2012 |
Sullivan TA, Geisert EE, Templeton JP, Rex TS. Dose-dependent treatment of optic nerve crush by exogenous systemic mutant erythropoietin. Experimental Eye Research. 96: 36-41. PMID 22306016 DOI: 10.1016/J.Exer.2012.01.006 |
0.67 |
|
2012 |
Sullivan T, Rex TS. Erratum to: Systemic Gene Delivery Protects the Photoreceptors in the Retinal Degeneration Slow Mouse Neurochemical Research. 37: 1598-1598. DOI: 10.1007/S11064-012-0785-2 |
0.726 |
|
2011 |
Sullivan TA, Geisert EE, Hines-Beard J, Rex TS. Systemic adeno-associated virus-mediated gene therapy preserves retinal ganglion cells and visual function in DBA/2J glaucomatous mice. Human Gene Therapy. 22: 1191-200. PMID 21542676 DOI: 10.1089/Hum.2011.052 |
0.734 |
|
2011 |
Sullivan T, Kodali K, Rex TS. Systemic gene delivery protects the photoreceptors in the retinal degeneration slow mouse. Neurochemical Research. 36: 613-8. PMID 20924671 DOI: 10.1007/S11064-010-0272-6 |
0.701 |
|
2009 |
Rex TS, Wong Y, Kodali K, Merry S. Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse. Experimental Eye Research. 89: 735-40. PMID 19591826 DOI: 10.1016/J.Exer.2009.06.017 |
0.535 |
|
2008 |
Allocca M, Doria M, Petrillo M, Colella P, Garcia-Hoyos M, Gibbs D, Kim SR, Maguire A, Rex TS, Di Vicino U, Cutillo L, Sparrow JR, Williams DS, Bennett J, Auricchio A. Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice. The Journal of Clinical Investigation. 118: 1955-64. PMID 18414684 DOI: 10.1172/Jci34316 |
0.638 |
|
2008 |
Bennicelli J, Wright JF, Komaromy A, Jacobs JB, Hauck B, Zelenaia O, Mingozzi F, Hui D, Chung D, Rex TS, Wei Z, Qu G, Zhou S, Zeiss C, Arruda VR, et al. Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 458-65. PMID 18209734 DOI: 10.1038/Sj.Mt.6300389 |
0.646 |
|
2008 |
Rex TS. Virus-mediated gene delivery to neuronal progenitors. Advances in Experimental Medicine and Biology. 613: 147-53. PMID 18188939 DOI: 10.1007/978-0-387-74904-4_16 |
0.345 |
|
2007 |
Rex TS. Rescue of sight by gene therapy - closer than it may appear. Ophthalmic Genetics. 28: 127-33. PMID 17896310 DOI: 10.1080/13816810701503707 |
0.484 |
|
2007 |
Shindler KS, Ventura E, Rex TS, Elliott P, Rostami A. SIRT1 activation confers neuroprotection in experimental optic neuritis. Investigative Ophthalmology & Visual Science. 48: 3602-9. PMID 17652729 DOI: 10.1167/Iovs.07-0131 |
0.401 |
|
2005 |
Rex TS, Peet JA, Surace EM, Calvert PD, Nikonov SS, Lyubarsky AL, Bendo E, Hughes T, Pugh EN, Bennett J. The distribution, concentration, and toxicity of enhanced green fluorescent protein in retinal cells after genomic or somatic (virus-mediated) gene transfer. Molecular Vision. 11: 1236-45. PMID 16402024 |
0.703 |
|
2005 |
Allocca M, Rex TS, Domenici L, Bennet J, Rivera VM, Auricchio A. 117. AAV-Mediated Erythropoietin Gene Transfer Protects from Genetic and Light-Induced Retinal Degeneration Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.122 |
0.614 |
|
2004 |
Rex TS, Tsui I, Hahn P, Maguire AM, Duan D, Bennett J, Dunaief JL. Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress. Human Gene Therapy. 15: 960-7. PMID 15585111 DOI: 10.1089/Hum.2004.15.960 |
0.582 |
|
2004 |
Wong WT, Rex TS, Auricchio A, Maguire AM, Chung D, Tang W, Bennett J. Effect of over-expression of pigment epithelium derived factor (PEDF) on developing retinal vasculature in the mouse. Molecular Vision. 10: 837-44. PMID 15547489 |
0.625 |
|
2004 |
Rex TS, Allocca M, Domenici L, Surace EM, Maguire AM, Lyubarsky A, Cellerino A, Bennett J, Auricchio A. Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 855-61. PMID 15509503 DOI: 10.1016/J.Ymthe.2004.07.027 |
0.78 |
|
2004 |
Dejneka NS, Surace EM, Aleman TS, Cideciyan AV, Lyubarsky A, Savchenko A, Redmond TM, Tang W, Wei Z, Rex TS, Glover E, Maguire AM, Pugh EN, Jacobson SG, Bennett J. In utero gene therapy rescues vision in a murine model of congenital blindness. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 182-8. PMID 14759802 DOI: 10.1016/J.Ymthe.2003.11.013 |
0.761 |
|
2003 |
Dejneka NS, Rex TS, Bennett J. Gene therapy and animal models for retinal disease. Developments in Ophthalmology. 37: 188-98. PMID 12876838 DOI: 10.1159/000072047 |
0.778 |
|
2003 |
Surace EM, Auricchio A, Reich SJ, Rex T, Glover E, Pineles S, Tang W, O'Connor E, Lyubarsky A, Savchenko A, Pugh EN, Maguire AM, Wilson JM, Bennett J. Delivery of adeno-associated virus vectors to the fetal retina: impact of viral capsid proteins on retinal neuronal progenitor transduction. Journal of Virology. 77: 7957-63. PMID 12829835 DOI: 10.1128/Jvi.77.14.7957-7963.2003 |
0.774 |
|
2002 |
Rex TS, Lewis GP, Geller SF, Fisher SK. Differential expression of cone opsin mRNA levels following experimental retinal detachment and reattachment. Molecular Vision. 8: 114-8. PMID 11979236 |
0.596 |
|
2002 |
Rex TS, Fariss RN, Lewis GP, Linberg KA, Sokal I, Fisher SK. A survey of molecular expression by photoreceptors after experimental retinal detachment. Investigative Ophthalmology & Visual Science. 43: 1234-47. PMID 11923271 |
0.621 |
|
2001 |
Fisher SK, Stone J, Rex TS, Linberg KA, Lewis GP. Experimental retinal detachment: a paradigm for understanding the effects of induced photoreceptor degeneration. Progress in Brain Research. 131: 679-98. PMID 11420980 DOI: 10.1016/S0079-6123(01)31053-1 |
0.688 |
|
2001 |
Linberg KA, Lewis GP, Shaaw C, Rex TS, Fisher SK. Distribution of S- and M-cones in normal and experimentally detached cat retina. The Journal of Comparative Neurology. 430: 343-56. PMID 11169472 DOI: 10.1002/1096-9861(20010212)430:3<343::Aid-Cne1035>3.0.Co;2-U |
0.622 |
|
1997 |
Rex TS. Rapid loss of blle and red/green cone opsin immunolabeling following experimental retinal detachment Investigative Ophthalmology and Visual Science. 38: S35. |
0.471 |
|
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