Guy Sella - Publications

Affiliations: 
Biological Sciences Columbia University, New York, NY 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fuller ZL, Berg JJ, Mostafavi H, Sella G, Przeworski M. Measuring intolerance to mutation in human genetics. Nature Genetics. PMID 30962618 DOI: 10.1038/S41588-019-0383-1  0.32
2016 Elyashiv E, Sattath S, Hu TT, Strutsovsky A, McVicker G, Andolfatto P, Coop G, Sella G. A Genomic Map of the Effects of Linked Selection in Drosophila. Plos Genetics. 12: e1006130. PMID 27536991 DOI: 10.1371/Journal.Pgen.1006130  0.32
2016 Hwang IY, Koh E, Kim HR, Yew WS, Chang MW. Reprogrammable microbial cell-based therapeutics against antibiotic-resistant bacteria. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 27: 59-71. PMID 27449598 DOI: 10.1016/j.drup.2016.06.002  0.4
2016 Tay SB, Chow JY, Go MK, Yew WS. Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases. Journal of Visualized Experiments : Jove. PMID 26779961 DOI: 10.3791/53243  0.48
2016 Gao Z, Wyman MJ, Sella G, Przeworski M. Interpreting the Dependence of Mutation Rates on Age and Time. Plos Biology. 14: e1002355. PMID 26761240 DOI: 10.1371/Journal.Pbio.1002355  0.32
2015 Gao Z, Przeworski M, Sella G. Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species. Evolution; International Journal of Organic Evolution. 69: 431-46. PMID 25403856 DOI: 10.1111/Evo.12567  0.32
2014 Cheung VW, Xue B, Hernandez-Valladares M, Go MK, Tung A, Aguda AH, Robinson RC, Yew WS. Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis. Plos One. 9: e103598. PMID 25072253 DOI: 10.1371/journal.pone.0103598  0.4
2014 Odokonyero D, Sakai A, Patskovsky Y, Malashkevich VN, Fedorov AA, Bonanno JB, Fedorov EV, Toro R, Agarwal R, Wang C, Ozerova ND, Yew WS, Sauder JM, Swaminathan S, Burley SK, et al. Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family. Proceedings of the National Academy of Sciences of the United States of America. 111: 8535-40. PMID 24872444 DOI: 10.1073/Pnas.1318703111  0.4
2014 Simons YB, Turchin MC, Pritchard JK, Sella G. The deleterious mutation load is insensitive to recent population history. Nature Genetics. 46: 220-4. PMID 24509481 DOI: 10.1038/Ng.2896  0.32
2014 Chow JY, Yang Y, Tay SB, Chua KL, Yew WS. Disruption of biofilm formation by the human pathogen Acinetobacter baumannii using engineered quorum-quenching lactonases. Antimicrobial Agents and Chemotherapy. 58: 1802-5. PMID 24379199 DOI: 10.1128/AAC.02410-13  0.4
2013 Tay SB, Yew WS. Development of quorum-based anti-virulence therapeutics targeting Gram-negative bacterial pathogens. International Journal of Molecular Sciences. 14: 16570-99. PMID 23939429 DOI: 10.3390/ijms140816570  0.72
2013 Xue B, Chow JY, Baldansuren A, Yap LL, Gan YH, Dikanov SA, Robinson RC, Yew WS. Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry. 52: 2359-70. PMID 23461395 DOI: 10.1021/Bi4000904  0.4
2013 Leffler EM, Gao Z, Pfeifer S, Ségurel L, Auton A, Venn O, Bowden R, Bontrop R, Wall JD, Sella G, Donnelly P, McVean G, Przeworski M. Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science (New York, N.Y.). 339: 1578-82. PMID 23413192 DOI: 10.1126/Science.1234070  0.32
2012 Ségurel L, Thompson EE, Flutre T, Lovstad J, Venkat A, Margulis SW, Moyse J, Ross S, Gamble K, Sella G, Ober C, Przeworski M. The ABO blood group is a trans-species polymorphism in primates. Proceedings of the National Academy of Sciences of the United States of America. 109: 18493-8. PMID 23091028 DOI: 10.1073/Pnas.1210603109  0.32
2012 Go MK, Chow JY, Cheung VW, Lim YP, Yew WS. Establishing a toolkit for precursor-directed polyketide biosynthesis: exploring substrate promiscuities of acid-CoA ligases. Biochemistry. 51: 4568-79. PMID 22587726 DOI: 10.1021/bi300425j  0.4
2011 Sattath S, Elyashiv E, Kolodny O, Rinott Y, Sella G. Pervasive adaptive protein evolution apparent in diversity patterns around amino acid substitutions in Drosophila simulans. Plos Genetics. 7: e1001302. PMID 21347283 DOI: 10.1371/Journal.Pgen.1001302  0.32
2011 Hernandez RD, Kelley JL, Elyashiv E, Melton SC, Auton A, McVean G, Sella G, Przeworski M. Classic selective sweeps were rare in recent human evolution. Science (New York, N.Y.). 331: 920-4. PMID 21330547 DOI: 10.1126/Science.1198878  0.32
2010 Chow JY, Xue B, Lee KH, Tung A, Wu L, Robinson RC, Yew WS. Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily. The Journal of Biological Chemistry. 285: 40911-20. PMID 20980257 DOI: 10.1074/jbc.M110.177139  0.4
2010 Elyashiv E, Bullaughey K, Sattath S, Rinott Y, Przeworski M, Sella G. Shifts in the intensity of purifying selection: an analysis of genome-wide polymorphism data from two closely related yeast species. Genome Research. 20: 1558-73. PMID 20817943 DOI: 10.1101/Gr.108993.110  0.32
2010 Huang S, Chua JH, Yew WS, Sivaraman J, Moore PK, Tan CH, Deng LW. Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production. Journal of Molecular Biology. 396: 708-18. PMID 19961860 DOI: 10.1016/J.Jmb.2009.11.058  0.4
2009 Sella G, Petrov DA, Przeworski M, Andolfatto P. Pervasive natural selection in the Drosophila genome? Plos Genetics. 5: e1000495. PMID 19503600 DOI: 10.1371/Journal.Pgen.1000495  0.32
2009 Cai JJ, Macpherson JM, Sella G, Petrov DA. Pervasive hitchhiking at coding and regulatory sites in humans. Plos Genetics. 5: e1000336. PMID 19148272 DOI: 10.1371/Journal.Pgen.1000336  0.32
2007 Macpherson JM, Sella G, Davis JC, Petrov DA. Genomewide spatial correspondence between nonsynonymous divergence and neutral polymorphism reveals extensive adaptation in Drosophila. Genetics. 177: 2083-99. PMID 18073425 DOI: 10.1534/Genetics.107.080226  0.32
2006 Yew WS, Fedorov AA, Fedorov EV, Wood BM, Almo SC, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: D-tartrate dehydratase from Bradyrhizobium japonicum Biochemistry. 45: 14598-14608. PMID 17144653 DOI: 10.1021/Bi061688G  0.44
2006 Yew WS, Fedorov AA, Fedorov EV, Rakus JF, Pierce RW, Almo SC, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: L-fuconate dehydratase from Xanthomonas campestris Biochemistry. 45: 14582-14597. PMID 17144652 DOI: 10.1021/Bi061687O  0.4
2006 Sella G, Ardell DH. The coevolution of genes and genetic codes: Crick's frozen accident revisited. Journal of Molecular Evolution. 63: 297-313. PMID 16838217 DOI: 10.1007/S00239-004-0176-7  0.32
2006 Sakai A, Xiang DF, Xu C, Song L, Yew WS, Raushel FM, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: N-succinylamino acid racemase and a new pathway for the irreversible conversion of D- to L-amino acids. Biochemistry. 45: 4455-62. PMID 16584181 DOI: 10.1021/Bi060230B  0.4
2005 Sella G, Hirsh AE. The application of statistical physics to evolutionary biology. Proceedings of the National Academy of Sciences of the United States of America. 102: 9541-6. PMID 15980155 DOI: 10.1073/Pnas.0501865102  0.32
2005 Wise EL, Yew WS, Akana J, Gerlt JA, Rayment I. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry. 44: 1816-23. PMID 15697207 DOI: 10.1021/Bi0478143  0.52
2005 Yew WS, Akana J, Wise EL, Rayment I, Gerlt JA. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry. 44: 1807-15. PMID 15697206 DOI: 10.1021/Bi047815V  0.64
2004 Wise EL, Yew WS, Gerlt JA, Rayment I. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: crystallographic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry. 43: 6438-46. PMID 15157078 DOI: 10.1021/bi0497392  0.4
2004 Yew WS, Wise EL, Rayment I, Gerlt JA. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: mechanistic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase. Biochemistry. 43: 6427-37. PMID 15157077 DOI: 10.1021/Bi049741T  0.6
2003 Wise EL, Yew WS, Gerlt JA, Rayment I. Structural evidence for a 1,2-enediolate intermediate in the reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase, a member of the orotidine 5'-monophosphate decarboxylase suprafamily. Biochemistry. 42: 12133-42. PMID 14567674 DOI: 10.1021/Bi0348819  0.44
2002 Ardell DH, Sella G. No accident: genetic codes freeze in error-correcting patterns of the standard genetic code. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 357: 1625-42. PMID 12495519 DOI: 10.1098/Rstb.2002.1071  0.32
2002 Sella G, Ardell DH. The impact of message mutation on the fitness of a genetic code. Journal of Molecular Evolution. 54: 638-51. PMID 11965436 DOI: 10.1007/S00239-001-0060-7  0.32
1999 Kurup A, San LM, Yew WS. Acute hepatitis A in a traveler who had received preexposure inactivated hepatitis A virus vaccine. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 28: 1324-5. PMID 10451178 DOI: 10.1086/517784  0.32
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