Kenneth Hoehn, D Phil - Publications

Affiliations: 
Yale University, New Haven, CT 

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Csepregi L, Hoehn K, Neumeier D, Taft JM, Friedensohn S, Weber CR, Kummer A, Sesterhenn F, Correia BE, Reddy ST. The physiological landscape and specificity of antibody repertoires are consolidated by multiple immunizations. Elife. 13. PMID 39693231 DOI: 10.7554/eLife.92718  0.33
2024 McIntire KM, Meng H, Lin TH, Kim W, Moore NE, Han J, McMahon M, Wang M, Malladi SK, Mohammed BM, Zhou JQ, Schmitz AJ, Hoehn KB, Carreño JM, Yellin T, et al. Maturation of germinal center B cells after influenza virus vaccination in humans. The Journal of Experimental Medicine. 221. PMID 38935072 DOI: 10.1084/jem.20240668  0.616
2024 Jensen CG, Sumner JA, Kleinstein SH, Hoehn KB. Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. Journal of Immunology (Baltimore, Md. : 1950). PMID 38557795 DOI: 10.4049/jimmunol.2300851  0.55
2024 Ota M, Hoehn KB, Fernandes-Braga W, Ota T, Aranda CJ, Friedman S, Miranda-Waldetario MGC, Redes J, Suprun M, Grishina G, Sampson HA, Malbari A, Kleinstein SH, Sicherer SH, Curotto de Lafaille MA. CD23IgG1 memory B cells are poised to switch to pathogenic IgE production in food allergy. Science Translational Medicine. 16: eadi0673. PMID 38324641 DOI: 10.1126/scitranslmed.adi0673  0.643
2024 Callahan D, Smita S, Joachim S, Hoehn K, Kleinstein S, Weisel F, Chikina M, Shlomchik M. Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states. Nature Immunology. PMID 38200277 DOI: 10.1038/s41590-023-01721-9  0.615
2023 Hoehn KB, Kleinstein SH. B cell phylogenetics in the single cell era. Trends in Immunology. 45: 62-74. PMID 38151443 DOI: 10.1016/j.it.2023.11.004  0.671
2023 Jensen CG, Sumner JA, Kleinstein SH, Hoehn KB. Inferring B cell phylogenies from paired heavy and light chain BCR sequences with Dowser. Biorxiv : the Preprint Server For Biology. PMID 37873135 DOI: 10.1101/2023.09.29.560187  0.569
2023 Lopes de Assis F, Hoehn KB, Zhang X, Kardava L, Smith CD, El Merhebi O, Buckner CM, Trihemasava K, Wang W, Seamon CA, Chen V, Schaughency P, Cheung F, Martins AJ, Chiang CI, et al. Tracking B cell responses to the SARS-CoV-2 mRNA-1273 vaccine. Cell Reports. 42: 112780. PMID 37440409 DOI: 10.1016/j.celrep.2023.112780  0.619
2023 Nickerson KM, Smita S, Hoehn KB, Marinov AD, Thomas KB, Kos JT, Yang Y, Bastacky SI, Watson CT, Kleinstein SH, Shlomchik MJ. Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice. The Journal of Experimental Medicine. 220. PMID 36828389 DOI: 10.1084/jem.20221346  0.658
2023 Ota M, Hoehn KB, Ota T, Aranda CJ, Friedman S, Braga WF, Malbari A, Kleinstein SH, Sicherer SH, Curotto de Lafaille MA. The memory of pathogenic IgE is contained within CD23 IgG1 memory B cells poised to switch to IgE in food allergy. Biorxiv : the Preprint Server For Biology. PMID 36747707 DOI: 10.1101/2023.01.25.525506  0.613
2023 Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic D, Papin A, Hoehn KB, Kots E, Ersching J, Bandyopadhyay A, Barin E, Poh HX, Evans CM, et al. mutation yields supercompetitive B cells primed for malignant transformation. Science (New York, N.Y.). 379: eabj7412. PMID 36656933 DOI: 10.1126/science.abj7412  0.46
2022 Asashima H, Mohanty S, Comi M, Ruff WE, Hoehn KB, Wong P, Klein J, Lucas C, Cohen I, Coffey S, Lele N, Greta L, Raddassi K, Chaudhary O, Unterman A, et al. PD-1CXCR5CD4 peripheral helper T cells promote CXCR3 plasmablasts in human acute viral infection. Cell Reports. 111895. PMID 36596303 DOI: 10.1016/j.celrep.2022.111895  0.635
2022 Xu Q, Milanez-Almeida P, Martins AJ, Radtke AJ, Hoehn KB, Oguz C, Chen J, Liu C, Tang J, Grubbs G, Stein S, Ramelli S, Kabat J, Behzadpour H, Karkanitsa M, et al. Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children. Nature Immunology. PMID 36536106 DOI: 10.1038/s41590-022-01367-z  0.599
2022 Fichtner ML, Hoehn KB, Ford EE, Mane-Damas M, Oh S, Waters P, Payne AS, Smith ML, Watson CT, Losen M, Martinez-Martinez P, Nowak RJ, Kleinstein SH, O'Connor KC. Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapy. Acta Neuropathologica Communications. 10: 154. PMID 36307868 DOI: 10.1186/s40478-022-01454-0  0.646
2022 Hoehn KB, Pybus OG, Kleinstein SH. Phylogenetic analysis of migration, differentiation, and class switching in B cells. Plos Computational Biology. 18: e1009885. PMID 35468128 DOI: 10.1371/journal.pcbi.1009885  0.615
2022 Manthiram K, Xu Q, Milanez-Almeida P, Martins A, Radtke A, Hoehn K, Chen J, Liu C, Tang J, Grubbs G, Stein S, Ramelli S, Kabat J, Behzadpour H, Karkanitsa M, et al. Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children. Research Square. PMID 35350206 DOI: 10.21203/rs.3.rs-1276578/v1  0.585
2022 Unterman A, Sumida TS, Nouri N, Yan X, Zhao AY, Gasque V, Schupp JC, Asashima H, Liu Y, Cosme C, Deng W, Chen M, Raredon MSB, Hoehn KB, Wang G, et al. Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19. Nature Communications. 13: 440. PMID 35064122 DOI: 10.1038/s41467-021-27716-4  0.626
2021 Hoehn KB, Turner JS, Miller FI, Jiang R, Pybus OG, Ali Ellebedy D, Kleinstein SH. Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving. Elife. 10. PMID 34787567 DOI: 10.7554/eLife.70873  0.54
2021 Ohm-Laursen L, Meng H, Hoehn KB, Nouri N, Jiang Y, Clouser C, Johnstone TG, Hause R, Sandhar BS, Upton NEG, Chevretton EB, Lakhani R, Corrigan CJ, Kleinstein SH, Gould HJ. B Cell Mobilization, Dissemination, Fine Tuning of Local Antigen Specificity and Isotype Selection in Asthma. Frontiers in Immunology. 12: 702074. PMID 34721376 DOI: 10.3389/fimmu.2021.702074  0.619
2021 Mandel-Brehm C, Fichtner ML, Jiang R, Winton VJ, Vazquez SE, Pham MC, Hoehn KB, Kelleher NL, Nowak RJ, Kleinstein SH, Wilson MR, DeRisi JL, O'Connor KC. Elevated N-Linked Glycosylation of IgG V Regions in Myasthenia Gravis Disease Subtypes. Journal of Immunology (Baltimore, Md. : 1950). PMID 34544801 DOI: 10.4049/jimmunol.2100225  0.552
2021 Jiang R, Meng H, Raddassi K, Fleming I, Hoehn KB, Dardick KR, Belperron AA, Montgomery RR, Shalek AK, Hafler DA, Kleinstein SH, Bockenstedt LK. Single cell immunophenotyping of the skin lesion erythema migrans Identifies IgM memory B cells. Jci Insight. PMID 34061047 DOI: 10.1172/jci.insight.148035  0.658
2021 Hoehn KB, Ramanathan P, Unterman A, Sumida TS, Asashima H, Hafler DA, Kaminski N, Dela Cruz CS, Sealfon SC, Bukreyev A, Kleinstein SH. Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19. Journal of Immunology (Baltimore, Md. : 1950). PMID 34049971 DOI: 10.4049/jimmunol.2100135  0.67
2021 Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, et al. Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children. Immunity. PMID 33891889 DOI: 10.1016/j.immuni.2021.04.003  0.548
2020 Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, et al. Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity. Medrxiv : the Preprint Server For Health Sciences. PMID 33300011 DOI: 10.1101/2020.12.01.20241364  0.549
2020 Jiang R, Hoehn KB, Lee CS, Pham MC, Homer RJ, Detterbeck FC, Aban I, Jacobson L, Vincent A, Nowak RJ, Kaminski HJ, Kleinstein SH, O'Connor KC. Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis. Proceedings of the National Academy of Sciences of the United States of America. PMID 33199596 DOI: 10.1073/pnas.2007206117  0.653
2020 Jiang R, Fichtner ML, Hoehn KB, Pham MC, Stathopoulos P, Nowak RJ, Kleinstein SH, O'Connor KC. Single-cell repertoire tracing identifies rituximab-resistant B cells during myasthenia gravis relapses. Jci Insight. PMID 32573488 DOI: 10.1172/Jci.Insight.136471  0.671
2020 Béguelin W, Teater M, Meydan C, Hoehn KB, Phillip JM, Soshnev AA, Venturutti L, Rivas MA, Calvo-Fernández MT, Gutierrez J, Camarillo JM, Takata K, Tarte K, Kelleher NL, Steidl C, et al. Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response. Cancer Cell. 37: 655-673.e11. PMID 32396861 DOI: 10.1016/J.Ccell.2020.04.004  0.625
2019 Austin JW, Buckner CM, Kardava L, Wang W, Zhang X, Melson VA, Swanson RG, Martins AJ, Zhou JQ, Hoehn KB, Fisk JN, Dimopoulos Y, Chassiakos A, O'Dell S, Smelkinson MG, et al. Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation. Science Translational Medicine. 11. PMID 31776286 DOI: 10.1126/Scitranslmed.Aax0904  0.601
2019 Hoehn KB, Vander Heiden JA, Zhou JQ, Lunter G, Pybus OG, Kleinstein SH. Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination. Proceedings of the National Academy of Sciences of the United States of America. PMID 31636219 DOI: 10.1073/Pnas.1906020116  0.591
2016 Hoehn KB, Fowler A, Lunter G, Pybus OG. The diversity and molecular evolution of B cell receptors during infection. Molecular Biology and Evolution. PMID 26802217 DOI: 10.1093/molbev/msw015  0.331
2015 Hoehn KB, Gall A, Bashford-Rogers R, Fidler SJ, Kaye S, Weber JN, McClure MO, Kellam P, Pybus OG. Dynamics of immunoglobulin sequence diversity in HIV-1 infected individuals. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26194755 DOI: 10.1098/Rstb.2014.0241  0.315
2014 Hoehn KB, Noor MA. How big is your Y? A genome sequence-based estimate of the size of the male-specific region in Megaselia scalaris. G3 (Bethesda, Md.). 5: 45-8. PMID 25380730 DOI: 10.1534/g3.114.015057  0.441
2012 Hoehn KB, McGaugh SE, Noor MA. Effects of premature termination codon polymorphisms in the Drosophila pseudoobscura subclade. Journal of Molecular Evolution. 75: 141-50. PMID 23132097 DOI: 10.1007/s00239-012-9528-x  0.463
2011 Stevison LS, Hoehn KB, Noor MA. Effects of inversions on within- and between-species recombination and divergence. Genome Biology and Evolution. 3: 830-41. PMID 21828374 DOI: 10.1093/gbe/evr081  0.45
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