Mauro Giacca - Publications

Affiliations: 
Molecular Medicine University of Trieste, Trieste, TS, Italy 

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Roy R, Cannata A, Al-Agil M, Ferone E, Jordan A, To-Dang B, Sadler M, Shamsi A, Albarjas M, Piper S, Giacca M, Shah AM, McDonagh T, Bromage DI, Scott PA. Diagnostic accuracy, clinical characteristics, and prognostic differences of patients with acute myocarditis according to inclusion criteria. European Heart Journal. Quality of Care & Clinical Outcomes. PMID 37930743 DOI: 10.1093/ehjqcco/qcad061  0.505
2023 Gortan Cappellari G, Aleksova A, Dal Ferro M, Cannatà A, Semolic A, Guarnaccia A, Zanetti M, Giacca M, Sinagra G, Barazzoni R. -3 PUFA-Enriched Diet Preserves Skeletal Muscle Mitochondrial Function and Redox State and Prevents Muscle Mass Loss in Mice with Chronic Heart Failure. Nutrients. 15. PMID 37513526 DOI: 10.3390/nu15143108  0.537
2022 Paldino A, Dal Ferro M, Stolfo D, Gandin I, Medo K, Graw S, Gigli M, Gagno G, Zaffalon D, Castrichini M, Masè M, Cannatà A, Brun F, Storm G, Severini GM, ... ... Giacca M, et al. Prognostic Prediction of Genotype vs Phenotype in Genetic Cardiomyopathies. Journal of the American College of Cardiology. 80: 1981-1994. PMID 36396199 DOI: 10.1016/j.jacc.2022.08.804  0.508
2022 Cannata A, Bhatti P, Roy R, Al-Agil M, Daniel A, Ferone E, Jordan A, Cassimon B, Bradwell S, Khawaja A, Sadler M, Shamsi A, Huntington J, Birkinshaw A, Rind I, ... ... Giacca M, et al. Prognostic relevance of demographic factors in cardiac magnetic resonance-proven acute myocarditis: A cohort study. Frontiers in Cardiovascular Medicine. 9: 1037837. PMID 36312271 DOI: 10.3389/fcvm.2022.1037837  0.52
2022 Ruozi G, Bortolotti F, Mura A, Tomczyk M, Falcione A, Martinelli V, Vodret S, Braga L, Dal Ferro M, Cannatà A, Zentilin L, Sinagra G, Zacchigna S, Giacca M. Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library. Science Translational Medicine. 14: eabo0699. PMID 36044596 DOI: 10.1126/scitranslmed.abo0699  0.569
2022 Nuzzi V, Del Mestre E, Degrassi A, Bromage DI, Manca P, Piper S, Artico J, Gentile P, Scott PA, Chiatto M, Merlo M, Pareek N, Giacca M, Sinagra G, McDonagh TA, et al. Cardiovascular Damage in COVID-19: What We Know Two Years Later. Current Cardiology Reports. PMID 35751835 DOI: 10.1007/s11886-022-01730-4  0.527
2021 Cannata A, Watson SA, Daniel A, Giacca M, Shah AM, McDonagh TA, Scott PA, Bromage DI. Impact of the COVID-19 pandemic on in-hospital mortality in cardiovascular disease: a meta-analysis. European Journal of Preventive Cardiology. PMID 34297822 DOI: 10.1093/eurjpc/zwab119  0.498
2021 Tini G, Cannatà A, Canepa M, Masci PG, Pardini M, Giacca M, Sinagra G, Marchionni N, Del Monte F, Udelson JE, Olivotto I. Is heart failure with preserved ejection fraction a 'dementia' of the heart? Heart Failure Reviews. PMID 33907929 DOI: 10.1007/s10741-021-10114-9  0.544
2021 Braga L, Ali H, Secco I, Chiavacci E, Neves G, Goldhill D, Penn R, Jimenez-Guardeño JM, Ortega-Prieto AM, Bussani R, Cannatà A, Rizzari G, Collesi C, Schneider E, Arosio D, ... ... Giacca M, et al. Drugs that inhibit TMEM16 proteins block SARS-CoV-2 Spike-induced syncytia. Nature. PMID 33827113 DOI: 10.1038/s41586-021-03491-6  0.54
2020 Gortan Cappellari G, Aleksova A, Dal Ferro M, Cannatà A, Semolic A, Zanetti M, Springer J, Anker SD, Giacca M, Sinagra G, Barazzoni R. Preserved Skeletal Muscle Mitochondrial Function, Redox State, Inflammation and Mass in Obese Mice with Chronic Heart Failure. Nutrients. 12. PMID 33158222 DOI: 10.3390/nu12113393  0.522
2020 Tocchetti CG, Ameri P, de Boer RA, D'Alessandra Y, Russo M, Sorriento D, Ciccarelli M, Kiss B, Bertrand L, Dawson D, Falcao-Pires I, Giacca M, Hamdani N, Linke WA, Mayr M, et al. Cardiac dysfunction in cancer patients: beyond direct cardiomyocyte damage of anticancer drugs. Novel cardio-oncology insights from the joint 2019 meeting of the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart. Cardiovascular Research. PMID 32683451 DOI: 10.1093/Cvr/Cvaa222  0.305
2020 Merlo M, Cannatà A, Pio Loco C, Stolfo D, Barbati G, Artico J, Gentile P, De Paris V, Ramani F, Zecchin M, Gigli M, Pinamonti B, Korcova R, Di Lenarda A, Giacca M, et al. Contemporary Survival Trends and etiological characterization in non-ischemic Dilated Cardiomyopathy. European Journal of Heart Failure. PMID 32452075 DOI: 10.1002/Ejhf.1914  0.554
2020 Cannatà A, Ali H, Sinagra G, Giacca M. Gene Therapy for the Heart Lessons Learned and Future Perspectives. Circulation Research. 126: 1394-1414. PMID 32379579 DOI: 10.1161/Circresaha.120.315855  0.607
2020 Zacchigna S, Paldino A, Falcão-Pires I, Daskalopoulos EP, Dal Ferro M, Vodret S, Lesizza P, Cannatà A, Miranda-Silva D, Lourenço AP, Pinamonti B, Sinagra G, Weinberger F, Eschenhagen T, Carrier L, ... ... Giacca M, et al. Toward standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function. Cardiovascular Research. PMID 32365197 DOI: 10.1093/Cvr/Cvaa110  0.584
2020 Kocijan T, Rehman M, Colliva A, Groppa E, Leban M, Vodret S, Volf N, Zucca G, Cappelletto A, Piperno GM, Zentilin L, Giacca M, Benvenuti F, Bin Z, Adams R, et al. Genetic lineage tracing reveals poor angiogenic potential of cardiac endothelial cells. Cardiovascular Research. PMID 31999325 DOI: 10.1093/Cvr/Cvaa012  0.323
2019 Ali H, Braga L, Giacca M. Cardiac regeneration and remodelling of the cardiomyocyte cytoarchitecture. The Febs Journal. PMID 31743572 DOI: 10.1111/Febs.15146  0.313
2019 Gabisonia K, Prosdocimo G, Aquaro GD, Carlucci L, Zentilin L, Secco I, Ali H, Braga L, Gorgodze N, Bernini F, Burchielli S, Collesi C, Zandonà L, Sinagra G, Piacenti M, ... ... Giacca M, et al. MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs. Nature. PMID 31068698 DOI: 10.1038/S41586-019-1191-6  0.328
2019 Balbi C, Lodder K, Costa A, Moimas S, Moccia F, van Herwaarden T, Rosti V, Campagnoli F, Palmeri A, De Biasio P, Santini F, Giacca M, Goumans MJ, Barile L, Smits AM, et al. Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome. International Journal of Cardiology. PMID 30987834 DOI: 10.1016/J.Ijcard.2019.04.011  0.302
2019 Paradies P, Carlucci L, Woitek F, Staffieri F, Lacitignola L, Ceci L, Romano D, Sasanelli M, Zentilin L, Giacca M, Salvadori S, Crovace A, Recchia FA. Intracoronary Gene Delivery of the Cytoprotective Factor Vascular Endothelial Growth Factor-B in Canine Patients with Dilated Cardiomyopathy: A Short-Term Feasibility Study. Veterinary Sciences. 6. PMID 30845635 DOI: 10.3390/Vetsci6010023  0.316
2019 Colliva A, Braga L, Giacca M, Zacchigna S. Endothelial-cardiomyocyte cross-talk in heart development and disease. The Journal of Physiology. PMID 30816576 DOI: 10.1113/Jp276758  0.325
2019 Ali H, Mano M, Braga L, Naseem A, Marini B, Vu DM, Collesi C, Meroni G, Lusic M, Giacca M. Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation. Nature Communications. 10: 926. PMID 30804369 DOI: 10.1038/S41467-019-08810-0  0.311
2018 Montagna C, Petris G, Casini A, Maule G, Franceschini GM, Zanella I, Conti L, Arnoldi F, Burrone OR, Zentilin L, Zacchigna S, Giacca M, Cereseto A. VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9. Molecular Therapy. Nucleic Acids. 12: 453-462. PMID 30195783 DOI: 10.1016/J.Omtn.2018.05.010  0.302
2018 Secco I, Barile L, Torrini C, Zentilin L, Vassalli G, Giacca M, Collesi C. Notch pathway activation enhances cardiosphere in vitro expansion. Journal of Cellular and Molecular Medicine. PMID 30138533 DOI: 10.1111/Jcmm.13832  0.325
2018 van den Hoogenhof MMG, van der Made I, de Groot NE, Damanafshan A, van Amersfoorth SCM, Zentilin L, Giacca M, Pinto YM, Creemers EE. AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart. Scientific Reports. 8: 11696. PMID 30076363 DOI: 10.1038/S41598-018-29552-X  0.34
2018 Braga L, Ferro MD, Mano M, Eulalio A, Ali H, Cannata A, Torrini C, Zentilin L, Zacchigna S, Giacca M. 232Administration of miR-665 modulates cardiomiocyte mechanotransduction and prevents pathological cardiac remodelling after pressure overload Cardiovascular Research. 114. DOI: 10.1093/Cvr/Cvy060.163  0.56
2018 Cappellari GG, Aleksova A, Ferro MD, Cannatà A, Semolic A, Zanetti M, Springer J, Anker SD, Giacca M, Sinagra G, Barazzoni R. Preserved skeletal muscle mitochondrial function, redox state and mass in obese mice with chronic heart failure Clinical Nutrition. 37. DOI: 10.1016/J.Clnu.2018.06.1373  0.566
2017 Johansen AK, Molenaar B, Versteeg D, Leitoguinho AR, Demkes CJ, Spanjaard B, de Ruiter H, Akbari Moqadam FA, Kooijman L, Zentilin L, Giacca M, van Rooij E. Postnatal Cardiac Gene-Editing Using CRISPR/Cas9 with AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption. Circulation Research. PMID 28851809 DOI: 10.1161/Circresaha.116.310370  0.339
2017 Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, et al. Id genes are essential for early heart formation. Genes & Development. PMID 28794185 DOI: 10.1101/Gad.300400.117  0.325
2017 Bortolotti F, Ruozi G, Falcione A, Doimo S, Dal Ferro M, Lesizza P, Zentilin L, Banks L, Zacchigna S, Giacca M. In Vivo Functional Selection Identifies Cardiotrophin-1 as a Cardiac Engraftment Factor for Mesenchymal Stromal Cells. Circulation. PMID 28754835 DOI: 10.1161/Circulationaha.117.029003  0.338
2017 Eschenhagen T, Bolli R, Braun T, Field LJ, Fleischmann BK, Frisén J, Giacca M, Hare JM, Houser SR, Lee RT, Marbán E, Martin JF, Molkentin JD, Murry CE, Riley PR, et al. Cardiomyocyte Regeneration: A Consensus Statement. Circulation. PMID 28684531 DOI: 10.1161/Circulationaha.117.029343  0.309
2017 Agostini S, Ali H, Vardabasso C, Fittipaldi A, Tasciotti E, Cereseto A, Bugatti A, Rusnati M, Lusic M, Giacca M. Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na(+),K(+)-ATPase Blocks HIV-1 Infection. Ebiomedicine. PMID 28645727 DOI: 10.1016/J.Ebiom.2017.06.011  0.303
2017 Prosdocimo G, Giacca M. Manipulating the Proliferative Potential of Cardiomyocytes by Gene Transfer. Methods in Molecular Biology (Clifton, N.J.). 1553: 41-53. PMID 28229406 DOI: 10.1007/978-1-4939-6756-8_4  0.355
2016 Cannatà A, Camparini L, Sinagra G, Giacca M, Loffredo FS. Pathways for salvage and protection of the heart under stress: novel routes for cardiac rejuvenation. Cardiovascular Research. 111: 142-53. PMID 27371745 DOI: 10.1093/Cvr/Cvw106  0.564
2016 Collesi C, Giacca M. Gene transfer to promote cardiac regeneration. Critical Reviews in Clinical Laboratory Sciences. 53: 359-69. PMID 27075546 DOI: 10.1080/10408363.2016.1176987  0.349
2015 Carroll KJ, Makarewich CA, McAnally J, Anderson DM, Zentilin L, Liu N, Giacca M, Bassel-Duby R, Olson EN. A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9. Proceedings of the National Academy of Sciences of the United States of America. PMID 26719419 DOI: 10.1073/Pnas.1523918113  0.326
2015 Mano M, Ippodrino R, Zentilin L, Zacchigna S, Giacca M. Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction. Proceedings of the National Academy of Sciences of the United States of America. 112: 11276-81. PMID 26305933 DOI: 10.1073/Pnas.1503607112  0.322
2015 Ruozi G, Bortolotti F, Falcione A, Dal Ferro M, Ukovich L, Macedo A, Zentilin L, Filigheddu N, Gortan Cappellari G, Baldini G, Zweyer M, Barazzoni R, Graziani A, Zacchigna S, Giacca M. AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Nature Communications. 6: 7388. PMID 26066847 DOI: 10.1038/Ncomms8388  0.326
2015 Marini B, Kertesz-Farkas A, Ali H, Lucic B, Lisek K, Manganaro L, Pongor S, Luzzati R, Recchia A, Mavilio F, Giacca M, Lusic M. Nuclear architecture dictates HIV-1 integration site selection. Nature. 521: 227-31. PMID 25731161 DOI: 10.1038/Nature14226  0.324
2015 Puzzi L, Marchetti L, Peverali FA, Biamonti G, Giacca M. DNA-protein interaction dynamics at the Lamin B2 replication origin. Cell Cycle (Georgetown, Tex.). 14: 64-73. PMID 25483070 DOI: 10.4161/15384101.2014.973337  0.301
2015 Lusic M, Giacca M. Regulation of HIV-1 latency by chromatin structure and nuclear architecture. Journal of Molecular Biology. 427: 688-94. PMID 25073101 DOI: 10.1016/J.Jmb.2014.07.022  0.314
2015 Zentilin L, Ippodrino R, Mano M, Giacca M. 39. Modulation of Histone Dosage and Chromatin Dynamics Regulates AAV Transduction Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33644-9  0.316
2014 Aguirre A, Montserrat N, Zacchigna S, Nivet E, Hishida T, Krause MN, Kurian L, Ocampo A, Vazquez-Ferrer E, Rodriguez-Esteban C, Kumar S, Moresco JJ, Yates JR, Campistol JM, Sancho-Martinez I, ... Giacca M, et al. In vivo activation of a conserved microRNA program induces mammalian heart regeneration. Cell Stem Cell. 15: 589-604. PMID 25517466 DOI: 10.1016/J.Stem.2014.10.003  0.306
2014 Zacchigna S, Zentilin L, Giacca M. Adeno-associated virus vectors as therapeutic and investigational tools in the cardiovascular system. Circulation Research. 114: 1827-46. PMID 24855205 DOI: 10.1161/Circresaha.114.302331  0.343
2014 Zacchigna S, Giacca M. Extra- and intracellular factors regulating cardiomyocyte proliferation in postnatal life. Cardiovascular Research. 102: 312-20. PMID 24623280 DOI: 10.1093/Cvr/Cvu057  0.321
2014 Quy VC, Carnevale V, Manganaro L, Lusic M, Rossetti G, Leone V, Fenollar-Ferrer C, Raugei S, Del Sal G, Giacca M, Carloni P. HIV-1 integrase binding to its cellular partners: a perspective from computational biology. Current Pharmaceutical Design. 20: 3412-21. PMID 24001231 DOI: 10.2174/13816128113199990631  0.316
2014 Tarone G, Cimino J, Rubinetto C, Moiso E, Cristofani F, Zentilin L, Giacca M, Bonne G, Brancaccio M. P330Overexpression of the muscle specific chaperone Melusin delays heart failure and mortality in a mouse model of Emery Dreyfus cardiomyopathy Cardiovascular Research. 103. DOI: 10.1093/Cvr/Cvu091.17  0.317
2013 Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stöger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schürmann N, ... ... Giacca M, et al. Macrophage microRNA-155 promotes cardiac hypertrophy and failure. Circulation. 128: 1420-32. PMID 23956210 DOI: 10.1161/Circulationaha.112.001357  0.312
2013 Lusic M, Marini B, Ali H, Lucic B, Luzzati R, Giacca M. Proximity to PML nuclear bodies regulates HIV-1 latency in CD4+ T cells. Cell Host & Microbe. 13: 665-77. PMID 23768491 DOI: 10.1016/J.Chom.2013.05.006  0.313
2013 Agostini S, Lionetti V, Matteucci M, Chiuppesi F, Giacca M, Pistello M, Recchia FA. A new dual-promoter system for cardiomyocyte-specific conditional induction of apoptosis. Biomed Research International. 2013: 845816. PMID 23573514 DOI: 10.1155/2013/845816  0.308
2013 Roehrich M, Barile L, Spicher A, Giacca M, Vassalli G. Characterization of Cardiac-derived Myelo-monocytoid Progenitor Cells Journal of Stem Cell Research & Therapy. 2013: 1-7. DOI: 10.4172/2157-7633.S9-002  0.33
2013 Brancaccio M, Cimino J, Rubinetto C, Zentilin L, Giacca M, Tarone G. Melusin gene therapy: a novel approach to fight familial dilated cardiomyopathy European Heart Journal. 34: 3410-3410. DOI: 10.1093/Eurheartj/Eht309.3410  0.324
2013 Woitek F, Hurst M, Ring N, Kulczycki AM, Lam A, Powers JC, Sabri A, Giacca M, Recchia FA. TCT-822 Effective Antegrade Cardiac Gene Therapy with VEGF-B167 for Pacing-induced Dilated Cardiomyopathy in a Pre-clinical Large Animal Model of Heart Failure Journal of the American College of Cardiology. 62: 248-249. DOI: 10.1016/J.Jacc.2013.08.1575  0.305
2012 Lovric J, Mano M, Zentilin L, Eulalio A, Zacchigna S, Giacca M. Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2087-97. PMID 22850678 DOI: 10.1038/Mt.2012.144  0.373
2012 Giacca M, Zacchigna S. VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond. Gene Therapy. 19: 622-629. PMID 22378343 DOI: 10.1038/Gt.2012.17  0.318
2012 Macedo A, Moriggi M, Vasso M, De Palma S, Sturnega M, Friso G, Gelfi C, Giacca M, Zacchigna S. Enhanced athletic performance on multisite AAV-IGF1 gene transfer coincides with massive modification of the muscle proteome. Human Gene Therapy. 23: 146-57. PMID 22017471 DOI: 10.1089/Hum.2011.157  0.308
2011 Della Chiara G, Crotti A, Liboi E, Giacca M, Poli G, Lusic M. Negative regulation of HIV-1 transcription by a heterodimeric NF-κB1/p50 and C-terminally truncated STAT5 complex. Journal of Molecular Biology. 410: 933-43. PMID 21763497 DOI: 10.1016/J.Jmb.2011.03.044  0.317
2011 Giacca M, Baker AH. Heartening results: the CUPID gene therapy trial for heart failure. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1181-2. PMID 21720375 DOI: 10.1038/Mt.2011.123  0.306
2011 Allouch A, Di Primio C, Alpi E, Lusic M, Arosio D, Giacca M, Cereseto A. The TRIM family protein KAP1 inhibits HIV-1 integration. Cell Host & Microbe. 9: 484-95. PMID 21669397 DOI: 10.1016/J.Chom.2011.05.004  0.318
2011 Di Stefano V, Giacca M, Capogrossi MC, Crescenzi M, Martelli F. Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycle Journal of Biological Chemistry. 286: 8644-8654. PMID 21209082 DOI: 10.1074/Jbc.M110.184549  0.316
2010 Mendoza-Maldonado R, Paolinelli R, Galbiati L, Giadrossi S, Giacca M. Interaction of the retinoblastoma protein with Orc1 and its recruitment to human origins of DNA replication. Plos One. 5: e13720. PMID 21085491 DOI: 10.1371/Journal.Pone.0013720  0.314
2010 Manganaro L, Lusic M, Gutierrez MI, Cereseto A, Del Sal G, Giacca M. Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes. Nature Medicine. 16: 329-33. PMID 20173753 DOI: 10.1038/Nm.2102  0.318
2010 Zentilin L, Puligadda U, Lionetti V, Zacchigna S, Collesi C, Pattarini L, Ruozi G, Camporesi S, Sinagra G, Pepe M, Recchia FA, Giacca M. Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1467-78. PMID 20019242 DOI: 10.1096/Fj.09-143180  0.32
2010 Jablonski JA, Amelio AL, Giacca M, Caputi M. The transcriptional transactivator Tat selectively regulates viral splicing. Nucleic Acids Research. 38: 1249-60. PMID 19966273 DOI: 10.1093/Nar/Gkp1105  0.314
2009 Urbinati C, Nicoli S, Giacca M, David G, Fiorentini S, Caruso A, Alfano M, Cassetta L, Presta M, Rusnati M. HIV-1 Tat and heparan sulfate proteoglycan interaction: a novel mechanism of lymphocyte adhesion and migration across the endothelium. Blood. 114: 3335-42. PMID 19661268 DOI: 10.1182/Blood-2009-01-198945  0.309
2009 Nappi F, Chiozzini C, Bordignon V, Borsetti A, Bellino S, Cippitelli M, Barillari G, Caputo A, Tyagi M, Giacca M, Ensoli B. Immobilized HIV-1 Tat protein promotes gene transfer via a transactivation-independent mechanism which requires binding of Tat to viral particles. The Journal of Gene Medicine. 11: 955-65. PMID 19653251 DOI: 10.1002/Jgm.1381  0.327
2009 Vardabasso C, Lusic M, Proudfoot N, Giacca M. Gene looping between the viral LTRs is a hallmark of transcriptionally active HIV-1 and Mo-MLV proviral DNA Retrovirology. 6. DOI: 10.1186/1742-4690-6-S2-P90  0.337
2009 Lusic M, Manganaro L, Vardabasso C, Gutierrez MI, Giacca M. Spatial juxtaposition of HIV-1 provirus with PML and KAKA bodies as revealed by 3D Immuno DNA FISH. Retrovirology. 6: 52. DOI: 10.1186/1742-4690-6-S2-P52  0.326
2009 Chiara GD, Crotti A, Giacca M, Poli G, Lusic M. Naturally C-Terminally truncated STAT5 (STAT5Δ): a novel negative controller of HIV-1 transcription and expression Retrovirology. 6: 27. DOI: 10.1186/1742-4690-6-S2-P27  0.321
2009 Allouch A, Liverani V, Arosio D, Gutierrez MI, Lusic M, Galli A, Giacca M, Cereseto A. HIV-1 acetylated integrase is targeted by KAP1 (TRIM28) to inhibit viral integration Retrovirology. 6: 2. DOI: 10.1186/1742-4690-6-S2-P2  0.336
2009 Giacca M. Novel and unexpected cellular partners for HIV-1 integrase and Tat Retrovirology. 6: 1-1. DOI: 10.1186/1742-4690-6-S2-I8  0.328
2008 Collesi C, Zentilin L, Sinagra G, Giacca M. Notch1 signaling stimulates proliferation of immature cardiomyocytes Journal of Cell Biology. 183: 117-128. PMID 18824567 DOI: 10.1083/Jcb.200806091  0.321
2008 Perkins KJ, Lusic M, Mitar I, Giacca M, Proudfoot NJ. Transcription-Dependent Gene Looping of the HIV-1 Provirus Is Dictated by Recognition of Pre-mRNA Processing Signals Molecular Cell. 29: 56-68. PMID 18206969 DOI: 10.1016/J.Molcel.2007.11.030  0.309
2007 Schwartz RA, Palacios JA, Cassell GD, Adam S, Giacca M, Weitzman MD. The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication. Journal of Virology. 81: 12936-45. PMID 17898048 DOI: 10.1128/Jvi.01523-07  0.313
2007 Crotti A, Lusic M, Lupo R, Lievens PM, Liboi E, Della Chiara G, Tinelli M, Lazzarin A, Patterson BK, Giacca M, Bovolenta C, Poli G. Naturally occurring C-terminally truncated STAT5 is a negative regulator of HIV-1 expression. Blood. 109: 5380-9. PMID 17332243 DOI: 10.1182/Blood-2006-08-042556  0.309
2006 Pegoraro G, Marcello A, Myers MP, Giacca M. Regulation of adeno-associated virus DNA replication by the cellular TAF-I/set complex. Journal of Virology. 80: 6855-64. PMID 16809291 DOI: 10.1128/Jvi.00383-06  0.307
2006 Ferrarini M, Arsic N, Recchia FA, Zentilin L, Zacchigna S, Xu X, Linke A, Giacca M, Hintze TH. Adeno-associated virus-mediated transduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs. Circulation Research. 98: 954-61. PMID 16543500 DOI: 10.1161/01.Res.0000217342.83731.89  0.325
2005 Tasciotti E, Giacca M. Fusion of the human immunodeficiency virus type 1 tat protein transduction domain to thymidine kinase increases bystander effect and induces enhanced tumor killing in vivo. Human Gene Therapy. 16: 1389-1403. PMID 16390270 DOI: 10.1089/Hum.2005.16.1389  0.312
2005 Cereseto A, Manganaro L, Gutierrez MI, Terreni M, Fittipaldi A, Lusic M, Marcello A, Giacca M. Acetylation of HIV‐1 integrase by p300 regulates viral integration The Embo Journal. 24: 3070-3081. PMID 16096645 DOI: 10.1038/Sj.Emboj.7600770  0.324
2005 Camozzi M, Zacchigna S, Rusnati M, Coltrini D, Ramirez-Correa G, Bottazzi B, Mantovani A, Giacca M, Presta M. Pentraxin 3 Inhibits Fibroblast Growth Factor 2–Dependent Activation of Smooth Muscle Cells In Vitro and Neointima Formation In Vivo Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1837-1842. PMID 16020751 DOI: 10.1161/01.Atv.0000177807.54959.7D  0.3
2005 Fittipaldi A, Giacca M. Transcellular protein transduction using the Tat protein of HIV-1. Advanced Drug Delivery Reviews. 57: 597-608. PMID 15722166 DOI: 10.1016/J.Addr.2004.10.011  0.33
2005 Giacca M. HIV-1 Tat, apoptosis and the mitochondria: a tubulin link? Retrovirology. 2: 7-7. PMID 15698476 DOI: 10.1186/1742-4690-2-7  0.306
2005 Marchiò S, Alfano M, Primo L, Gramaglia D, Butini L, Gennero L, De Vivo E, Arap W, Giacca M, Pasqualini R, Bussolino F. Cell surface-associated Tat modulates HIV-1 infection and spreading through a specific interaction with gp120 viral envelope protein. Blood. 105: 2802-11. PMID 15591114 DOI: 10.1182/Blood-2004-06-2212  0.306
2005 Ferrarini M, Arsic N, Zacchigna S, Recchia F, Zentilin L, Giacca M, Hintze T. 1087. Adeno-Associated Virus-Mediated Transduction of VEGF165 Markedly Improves Functional Recovery of Infarcted Myocardium in Chronically Instrumented Dogs Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.634  0.308
2005 Pegoraro G, Marcello A, Myers MP, Giacca M. 852. Human ANP32B Protein Binds AAV-2 Rep and Increases Viral Replication and rAAV Production Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.395  0.302
2005 Tafuro S, Zacchigna S, Zentilin L, Dapas M, Giacca M. 126. The Formation of Stable and Mature Blood Vessels Requires the Proper Timing of VEGF Expression Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.131  0.323
2004 Giacca M. The HIV-1 Tat protein: a multifaceted target for novel therapeutic opportunities. Current Drug Targets - Immune, Endocrine & Metabolic Disorders. 4: 277-285. PMID 15578978 DOI: 10.2174/1568008043339767  0.338
2004 Arsic N, Zacchigna S, Zentilin L, Ramirez-Correa G, Pattarini L, Salvi A, Sinagra G, Giacca M. Vascular endothelial growth factor stimulates skeletal muscle regeneration in Vivo Molecular Therapy. 10: 844-854. PMID 15509502 DOI: 10.1016/J.Ymthe.2004.08.007  0.302
2004 Paixão S, Colaluca IN, Cubells M, Peverali FA, Destro A, Giadrossi S, Giacca M, Falaschi A, Riva S, Biamonti G. Modular structure of the human lamin B2 replicator. Molecular and Cellular Biology. 24: 2958-67. PMID 15024083 DOI: 10.1128/Mcb.24.7.2958-2967.2004  0.301
2004 Marcello A, Lusic M, Pegoraro G, Pellegrini V, Beltram F, Giacca M. Nuclear organization and the control of HIV-1 transcription. Gene. 326: 1-11. PMID 14729258 DOI: 10.1016/J.Gene.2003.10.018  0.324
2004 Di Leva F, Ferrante MI, Demarchi F, Caravelli A, Matarazzo MR, Giacca M, D'Urso M, D'Esposito M, Franzé A. Human synaptobrevin-like 1 gene basal transcription is regulated through the interaction of selenocysteine tRNA gene transcription activating factor-zinc finger 143 factors with evolutionary conserved cis-elements. The Journal of Biological Chemistry. 279: 7734-9. PMID 14672948 DOI: 10.1074/Jbc.M308140200  0.307
2004 Tasciotti E, Giacca M. 600. Fusion of HSV-1 thymidine kinase to an 11 aa-peptide from the HIV-1 tat protein promotes intercellular trafficking and enhances anti-tumoral activity in vivo Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.524  0.31
2004 Fittipaldi A, Agostini S, Ferrari A, Arcangeli C, Pellegrini V, Beltram F, Giacca M. 365. Cell Membrane Lipid Rafts Mediate Caveolar Endocytosis of HIV-1 Tat Fusion Proteins Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.300  0.309
2004 Arsic N, Zacchigna S, Zentilin L, Ramirez-Correa G, Salvi A, Sinagra G, Giacca M. 236. Delivery of VEGF Using AAV Vectors Stimulates Skeletal Muscle Regeneration In Vivo Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.167  0.317
2003 Lusic M, Marcello A, Cereseto A, Giacca M. Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. The Embo Journal. 22: 6550-6561. PMID 14657027 DOI: 10.1093/Emboj/Cdg631  0.313
2003 Arsic N, Zentilin L, Zacchigna S, Santoro D, Stanta G, Salvi A, Sinagra G, Giacca M. Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors Molecular Therapy. 7: 450-459. PMID 12727107 DOI: 10.1016/S1525-0016(03)00034-0  0.305
2003 Brigati C, Giacca M, Noonan DM, Albini A. HIV Tat, its TARgets and the control of viral gene expression. Fems Microbiology Letters. 220: 57-65. PMID 12644228 DOI: 10.1016/S0378-1097(03)00067-3  0.35
2003 Tasciotti E, Zoppè M, Giacca M. Transcellular transfer of active HSV-1 thymidine kinase mediated by an 11-amino-acid peptide from HIV-1 Tat. Cancer Gene Therapy. 10: 64-74. PMID 12489030 DOI: 10.1038/Sj.Cgt.7700526  0.335
2001 Zentilin L, Marcello A, Giacca M. Involvement of Cellular Double-Stranded DNA Break Binding Proteins in Processing of the Recombinant Adeno-Associated Virus Genome Journal of Virology. 75: 12279-12287. PMID 11711618 DOI: 10.1128/Jvi.75.24.12279-12287.2001  0.318
2001 Marcello A, Zoppé M, Giacca M. Multiple modes of transcriptional regulation by the HIV-1 Tat transactivator. Iubmb Life. 51: 175-181. PMID 11547919 DOI: 10.1080/152165401753544241  0.31
2001 Rusnati M, Urbinati C, Caputo A, Possati L, Lortat-Jacob H, Giacca M, Ribatti D, Presta M. Pentosan polysulfate as an inhibitor of extracellular HIV-1 Tat. Journal of Biological Chemistry. 276: 22420-22425. PMID 11304529 DOI: 10.1074/Jbc.M010779200  0.317
2001 Tyagi M, Rusnati M, Presta M, Giacca M. Internalization of HIV-1 Tat Requires Cell Surface Heparan Sulfate Proteoglycans Journal of Biological Chemistry. 276: 3254-3261. PMID 11024024 DOI: 10.1074/Jbc.M006701200  0.309
2000 Rusnati M, Taraboletti G, Urbinati C, Tulipano G, Giuliani R, Molinari-Tosatti MP, Sennino B, Giacca M, Tyagi M, Albini A, Noonan D, Giavazzi R, Presta M. Thrombospondin-1/HIV-1 Tat protein interaction: modulation of the biological activity of extracellular Tat The Faseb Journal. 14: 1917-1930. PMID 11023976 DOI: 10.1096/Fj.99-0902Com  0.325
2000 de Stanchina E, Gabellini D, Norio P, Giacca M, Peverali FA, Riva S, Falaschi A, Biamonti G. Selection of homeotic proteins for binding to a human DNA replication origin. Journal of Molecular Biology. 299: 667-80. PMID 10835276 DOI: 10.1006/Jmbi.2000.3782  0.318
2000 Zentilin L, Qin G, Tafuro S, Dinauer MC, Baum C, Giacca M. Variegation of retroviral vector gene expression in myeloid cells. Gene Therapy. 7: 153-66. PMID 10673720 DOI: 10.1038/Sj.Gt.3301057  0.313
2000 Mitola S, Soldi R, Zanon I, Barra L, Gutierrez MI, Berkhout B, Giacca M, Bussolino F. Identification of Specific Molecular Structures of Human Immunodeficiency Virus Type 1 Tat Relevant for Its Biological Effects on Vascular Endothelial Cells Journal of Virology. 74: 344-353. PMID 10590123 DOI: 10.1128/Jvi.74.1.344-353.2000  0.315
1999 Marzio G, Giacca M. Chromatin control of HIV‐1 gene expression Genetica. 106: 125-130. PMID 10710718 DOI: 10.1023/A:1003797332379  0.341
1999 Todorovic V, Falaschi A, Giacca M. Replication origins of mammalian chromosomes: the happy few. Frontiers in Bioscience : a Journal and Virtual Library. 4: D859-68. PMID 10577395 DOI: 10.2741/Todorovic  0.314
1999 Demarchi F, Gutierrez MI, Giacca M. Human Immunodeficiency Virus Type 1 Tat Protein Activates Transcription Factor NF-κB through the Cellular Interferon-Inducible, Double-Stranded RNA-Dependent Protein Kinase, PKR Journal of Virology. 73: 7080-7086. PMID 10400814 DOI: 10.1128/Jvi.73.8.7080-7086.1999  0.322
1999 Chirivi RGS, Taraboletti G, Bani MR, Barra L, Piccinini G, Giacca M, Bussolino F, Giavazzi R. Human immunodeficiency virus-1 (HIV-1)-Tat protein promotes migration of acquired immunodeficiency syndrome-related lymphoma cells and enhances their adhesion to endothelial cells. Blood. 94: 1747-1754. DOI: 10.1182/Blood.V94.5.1747  0.322
1998 Marzio G, Tyagi M, Gutierrez MI, Giacca M. HIV-1 Tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter Proceedings of the National Academy of Sciences of the United States of America. 95: 13519-13524. PMID 9811832 DOI: 10.1073/Pnas.95.23.13519  0.332
1997 Comar M, Simonelli C, Zanussi S, Paoli Pd, Vaccher E, Tirelli U, Giacca M. Dynamics of HIV-1 mRNA Expression in Patients with Long-term Nonprogressive HIV-1 Infection Journal of Clinical Investigation. 100: 893-903. PMID 9259589 DOI: 10.1172/Jci119605  0.32
1996 Comar M, Marzio G, D'agaro P, Giacca M. Quantitative dynamics of HIV type 1 expression. Aids Research and Human Retroviruses. 12: 117-126. PMID 8834461 DOI: 10.1089/Aid.1996.12.117  0.311
1996 Milasin J, Muntoni F, Severini GM, Bartoloni L, Vatta M, Krajinovic M, Mateddu A, Angelini C, Camerini F, Falaschi A, Mestroni L, Giacca M. A point mutation in the 5' splice site of the dystrophin gene first intron responsible for X-linked dilated cardiomyopathy. Human Molecular Genetics. 5: 73-9. PMID 8789442 DOI: 10.1093/Hmg/5.1.73  0.31
1996 Giacca M, Borella S, Calderazzo F, Bianchi LC, D'agaro P, Rampazzo C, Bianchi V, Reichard P. Synergistic antiviral action of ribonucleotide reductase inhibitors and 3'-azido-3'-deoxythymidine on HIV type 1 infection in vitro. Aids Research and Human Retroviruses. 12: 677-682. PMID 8744578 DOI: 10.1089/Aid.1996.12.677  0.305
1996 Mestroni L, Krajinovic M, Severini GM, Milasin J, Pinamonti B, Rocco C, Vatta M, Falaschi A, Giacca M, Camerini F. Molecular genetics of dilated cardiomyopathies. European Heart Journal. 5-9. PMID 8682101 DOI: 10.1093/Eurheartj/16.Suppl_O.5  0.303
1996 Demarchi F, d'Adda di Fagagna F, Falaschi A, Giacca M. Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1. Journal of Virology. 70: 4427-37. PMID 8676466 DOI: 10.1128/Jvi.70.7.4427-4437.1996  0.307
1996 Zentilin L, Tafuro S, Grassi G, Garcia R, Ventura A, Baralle F, Falaschi A, Giacca M. Functional reconstitution of oxidase activity in X-linked chronic granulomatous disease by retrovirus-mediated gene transfer Experimental Cell Research. 225: 257-267. PMID 8660913 DOI: 10.1006/Excr.1996.0175  0.326
1996 Giacca M, Zanussi S, Comar M, Simonelli C, Vaccher E, Paoli Pd, Tirelli U. Treatment of Human Immunodeficiency Virus Infection with Hydroxyurea: Virologic and Clinical Evaluation The Journal of Infectious Diseases. 174: 204-209. PMID 8655996 DOI: 10.1093/Infdis/174.1.204  0.302
1996 Dimitrova DS, Giacca M, Demarchi F, Biamonti G, Riva S, Falaschi A. In vivo protein-DNA interactions at human DNA replication origin. Proceedings of the National Academy of Sciences of the United States of America. 93: 1498-503. PMID 8643660 DOI: 10.1073/Pnas.93.4.1498  0.33
1995 Falaschi A, Giacca M. The quest for a human ori. Genetica. 94: 255-66. PMID 7896144 DOI: 10.1007/Bf01443439  0.304
1995 Mestroni L, Krajinovic M, Severini GM, Pinamonti B, Di Lenarda A, Giacca M, Falaschi A, Camerini F. Familial dilated cardiomyopathy. British Heart Journal. 72: S35-41. PMID 7873323 DOI: 10.1136/Hrt.72.6_Suppl.S35  0.307
1995 d'Adda di Fagagna F, Marzio G, Gutierrez MI, Kang LY, Falaschi A, Giacca M. Molecular and functional interactions of transcription factor USF with the long terminal repeat of human immunodeficiency virus type 1. Journal of Virology. 69: 2765-75. PMID 7707499 DOI: 10.1128/Jvi.69.5.2765-2775.1995  0.309
1993 Demarchi F, D'Agaro P, Falaschi A, Giacca M. In vivo footprinting analysis of constitutive and inducible protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1. Journal of Virology. 67: 7450-60. PMID 8230466 DOI: 10.1128/Jvi.67.12.7450-7460.1993  0.329
1993 Biamonti G, Perini G, Weighardt F, Riva S, Giacca M, Norio P, Zentilin L, Diviacco S, Dimitrova D, Falaschi A. A human DNA replication origin: localization and transcriptional characterization. Chromosoma. 102: S24-31. PMID 1291239 DOI: 10.1007/Bf02451782  0.301
1992 Giacca M, Gutierrez MI, Menzo S, d'Adda di Fagagna F, Falaschi A. A human binding site for transcription factor USF/MLTF mimics the negative regulatory element of human immunodeficiency virus type 1. Virology. 186: 133-47. PMID 1727595 DOI: 10.1016/0042-6822(92)90067-Y  0.312
1992 Menzo S, Bagnarelli P, Giacca M, Manzin A, Varaldo PE, Clementi M. Absolute quantitation of viremia in human immunodeficiency virus infection by competitive reverse transcription and polymerase chain reaction. Journal of Clinical Microbiology. 30: 1752-7. PMID 1629331 DOI: 10.1128/Jcm.30.7.1752-1757.1992  0.324
1992 Demarchi F, D'Agaro P, Falaschi A, Giacca M. Probing protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1 by in vivo footprinting. Journal of Virology. 66: 2514-8. PMID 1548776 DOI: 10.1128/Jvi.66.4.2514-2518.1992  0.3
1992 Bagnarelli P, Menzo S, Valenza A, Manzin A, Giacca M, Ancarani F, Scalise G, Varaldo PE, Clementi M. Molecular profile of human immunodeficiency virus type 1 infection in symptomless patients and in patients with AIDS. Journal of Virology. 66: 7328-35. PMID 1433521 DOI: 10.1128/Jvi.66.12.7328-7335.1992  0.313
1989 Falaschi A, Biamonti G, Cobianchi F, Csordas-Toth E, Faulkner G, Giacca M, Pedacchia D, Perini G, Riva S, Tribioli C. Presence of transcription signals in two putative DNA replication origins of human cells. Biochimica Et Biophysica Acta. 951: 430-42. PMID 3145020 DOI: 10.1016/0167-4781(88)90117-0  0.309
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