Masahiro Akiyama - Publications

Affiliations: 
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 
 Nara Institute of Science and Technology, Ikoma-shi, Nara-ken, Japan 

21/66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Le LAT, Chang PY, Ando S, Conrad TM, Nunose S, Sakai A, Uefune H, Furukohri A, Akiyama MT, Maki H. Nutritional conditions and oxygen concentration affect spontaneous occurrence of homologous recombination events but not spontaneous mutagenesis in Escherichia coli. Genes & Genetic Systems. PMID 32389919 DOI: 10.1266/ggs.19-00008  0.317
2016 Akiyama MT, Oshima T, Chumsakul O, Ishikawa S, Maki H. Replication fork progression is paused in two large chromosomal zones flanking the DNA replication origin in Escherichia coli. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 27353572 DOI: 10.1111/gtc.12388  0.516
2015 Tan KW, Pham TM, Furukohri A, Maki H, Akiyama MT. Recombinase and translesion DNA polymerase decrease the speed of replication fork progression during the DNA damage response in Escherichia coli cells. Nucleic Acids Research. 43: 1714-25. PMID 25628359 DOI: 10.1093/nar/gkv044  0.504
2014 Ikeda M, Furukohri A, Philippin G, Loechler E, Akiyama MT, Katayama T, Fuchs RP, Maki H. DNA polymerase IV mediates efficient and quick recovery of replication forks stalled at N2-dG adducts. Nucleic Acids Research. 42: 8461-72. PMID 24957605 DOI: 10.1093/Nar/Gku547  0.481
2013 Pham TM, Tan KW, Sakumura Y, Okumura K, Maki H, Akiyama MT. A single-molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerase III is a major determinant of fork speed Molecular Microbiology. 90: 584-596. PMID 23998701 DOI: 10.1111/mmi.12386  0.496
2012 Ikeda M, Shinozaki Y, Uchida K, Ohshika Y, Furukohri A, Maki H, Akiyama MT. Quick replication fork stop by overproduction of Escherichia coli DinB produces non-proliferative cells with an aberrant chromosome. Genes & Genetic Systems. 87: 221-31. PMID 23229309 DOI: DN/JST.JSTAGE/ggs/87.221  0.474
2012 Mori T, Nakamura T, Okazaki N, Furukohri A, Maki H, Akiyama MT. Escherichia coli DinB inhibits replication fork progression without significantly inducing the SOS response. Genes & Genetic Systems. 87: 75-87. PMID 22820381 DOI: 10.1266/GGS.87.75  0.539
2012 Furukohri A, Nishikawa Y, Akiyama MT, Maki H. Interaction between Escherichia coli DNA polymerase IV and single-stranded DNA-binding protein is required for DNA synthesis on SSB-coated DNA. Nucleic Acids Research. 40: 6039-48. PMID 22447448 DOI: 10.1093/nar/gks264  0.511
2010 Ogawara D, Muroya T, Yamauchi K, Iwamoto TA, Yagi Y, Yamashita Y, Waga S, Akiyama M, Maki H. Near-full-length REV3L appears to be a scarce maternal factor in Xenopus laevis eggs that changes qualitatively in early embryonic development. Dna Repair. 9: 90-5. PMID 19896909 DOI: 10.1016/J.Dnarep.2009.10.004  0.641
2009 Yu S, Smirnova JB, Friedberg EC, Stillman B, Akiyama M, Owen-Hughes T, Waters R, Reed SH. ABF1-binding sites promote efficient global genome nucleotide excision repair. The Journal of Biological Chemistry. 284: 966-73. PMID 18996839 DOI: 10.1074/Jbc.M806830200  0.651
2008 Uchida K, Furukohri A, Shinozaki Y, Mori T, Ogawara D, Kanaya S, Nohmi T, Maki H, Akiyama M. Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal. Molecular Microbiology. 70: 608-22. PMID 18761688 DOI: 10.1111/J.1365-2958.2008.06423.X  0.527
2005 Yagi Y, Ogawara D, Iwai S, Hanaoka F, Akiyama M, Maki H. DNA polymerases eta and kappa are responsible for error-free translesion DNA synthesis activity over a cis-syn thymine dimer in Xenopus laevis oocyte extracts. Dna Repair. 4: 1252-69. PMID 16055392 DOI: 10.1016/J.Dnarep.2005.06.010  0.581
2005 Moritoh S, Miki D, Akiyama M, Kawahara M, Izawa T, Maki H, Shimamoto K. RNAi-mediated silencing of OsGEN-L (OsGEN-like), a new member of the RAD2/XPG nuclease family, causes male sterility by defect of microspore development in rice. Plant & Cell Physiology. 46: 699-715. PMID 15792960 DOI: 10.1093/Pcp/Pci090  0.308
2004 Fukui T, Yamauchi K, Muroya T, Akiyama M, Maki H, Sugino A, Waga S. Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 9: 179-91. PMID 15005706 DOI: 10.1111/J.1356-9597.2004.00716.X  0.686
2000 Reed SH, Akiyama M, Stillman B, Friedberg EC. Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair. Genes & Development. 13: 3052-8. PMID 10601031 DOI: 10.1101/Gad.13.23.3052  0.666
1999 Seki M, Akiyama M, Sugaya Y, Ohtsubo E, Maki H. Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli. Journal of Biological Chemistry. 274: 33313-33319. PMID 10559208 DOI: 10.1074/Jbc.274.47.33313  0.547
1990 Maki H, Akiyama M, Horiuchi T, Sekiguchi M. Molecular mechanisms of replicational fidelity in Escherichia coli. Basic Life Sciences. 52: 299-308. PMID 2158294 DOI: 10.1007/978-1-4615-9561-8_25  0.492
1989 Akiyama M, Maki H, Sekiguchi M, Horiuchi T. A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 86: 3949-3952. PMID 2657730 DOI: 10.1073/Pnas.86.11.3949  0.476
1988 Hidaka M, Akiyama M, Horiuchi T. A consensus sequence of three DNA replication terminus sites on the E. coli chromosome is highly homologous to the terR sites of the R6K plasmid. Cell. 55: 467-475. PMID 3052852 DOI: 10.1016/0092-8674(88)90033-5  0.67
1987 Horiuchi T, Hidaka M, Akiyama M, Nishitani H, Sekiguchi M. Replication intermediate of a hybrid plasmid carrying the replication terminus ( ter ) site of R6K as revealed by agarose gel electrophoresis Molecular Genetics and Genomics. 210: 394-398. PMID 3323842 DOI: 10.1007/Bf00327188  0.694
1987 Akiyama M, Horiuchi T, Sekiguchi M. Molecular cloning and nucleotide sequence of the mutT mutator of Escherichia coli that causes A:T to C:G transversion. Molecular Genetics and Genomics. 206: 9-16. PMID 3033442 DOI: 10.1007/Bf00326530  0.453
Low-probability matches (unlikely to be authored by this person)
2022 Shinkai Y, Onose Y, Akiyama M, Hirose R, Kumagai Y. Capture of Electrophilic Quinones in the Extracellular Space: Evidence for a Phase Zero Reaction. Chemical Research in Toxicology. 36: 23-31. PMID 36525601 DOI: 10.1021/acs.chemrestox.2c00223  0.201
2021 Abiko Y, Katayama Y, Akiyama M, Kumagai Y. Lipophilic compounds in garlic decrease the toxicity of methylmercury by forming sulfur adducts. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 150: 112061. PMID 33587975 DOI: 10.1016/j.fct.2021.112061  0.149
2024 Akiyama M, Uchiyama J, Kumagai Y, Kim YG. [Supersulfides to Regulate Electrophilic Stress]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 144: 47-50. PMID 38171794 DOI: 10.1248/yakushi.23-00162-2  0.137
2020 Unoki T, Akiyama M, Kumagai Y. Nrf2 Activation and Its Coordination with the Protective Defense Systems in Response to Electrophilic Stress. International Journal of Molecular Sciences. 21. PMID 31952233 DOI: 10.3390/ijms21020545  0.125
2022 Yakabe K, Higashi S, Akiyama M, Mori H, Murakami T, Toyoda A, Sugiyama Y, Kishino S, Okano K, Hirayama A, Gotoh A, Li S, Mori T, Katayama T, Ogawa J, et al. Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota. Cell Reports. 40: 111332. PMID 36103838 DOI: 10.1016/j.celrep.2022.111332  0.123
2024 Kodera H, Hirano R, Akiyama M, Matsumoto Y. Clinical utility of anti-Ro52 antibody confirmation in anti-MDA5 antibody-positive dermatomyositis: A Case Report. Modern Rheumatology Case Reports. PMID 38753322 DOI: 10.1093/mrcr/rxae027  0.12
2024 Aoki H, Shinkai Y, Akiyama M, Yamazaki S, Nishida M, Kumagai Y. Extracellularly secreted cysteine derived from cystine regulates oxidative and electrophilic stress in HepG2 cells. Free Radical Research. 1-10. PMID 38733204 DOI: 10.1080/10715762.2024.2350524  0.12
2021 Seki N, Akiyama M, Yamakawa H, Hase K, Kumagai Y, Kim YG. Adverse effects of methylmercury on gut bacteria and accelerated accumulation of mercury in organs due to disruption of gut microbiota. The Journal of Toxicological Sciences. 46: 91-97. PMID 33536393 DOI: 10.2131/jts.46.91  0.118
2020 Henderson CF, Bica I, Long F, Irwin D, Stull CH, Baker BW, Suarez Vega V, Taugher ZM, Fletes ED, Bartleson JM, Humphrey ML, Álvarez L, Akiyama M, Kumagai Y, Fukuto JM, et al. Cysteine Trisulfide Protects from Electrophile-Induced Death Through the Generation of Cysteine Hydropersulfide. Chemical Research in Toxicology. PMID 31977195 DOI: 10.1021/acs.chemrestox.9b00494  0.116
2019 Kumagai Y, Akiyama M, Unoki T. Adaptive Responses to Electrophilic Stress and Reactive Sulfur Species as their Regulator Molecules. Toxicological Research. 35: 303-310. PMID 31636841 DOI: 10.5487/TR.2019.35.4.303  0.114
2019 Lin J, Akiyama M, Bica I, Long FT, Henderson CF, Goddu RN, Suarez V, Baker B, Ida T, Shinkai Y, Nagy P, Akaike T, Fukuto JM, Kumagai Y. The Uptake and Release of Polysulfur Cysteine Species by Cells: Physiological and Toxicological Implications. Chemical Research in Toxicology. PMID 30681327 DOI: 10.1021/acs.chemrestox.8b00340  0.11
2022 Horai S, Abiko Y, Unoki T, Shinkai Y, Akiyama M, Nakata K, Kunisue T, Kumagai Y. Concentrations of nucleophilic sulfur species in small Indian mongoose (Herpestes auropunctatus) in Okinawa, Japan. Chemosphere. 295: 133833. PMID 35120952 DOI: 10.1016/j.chemosphere.2022.133833  0.107
2017 Shinkai Y, Masuda A, Akiyama M, Xian M, Kumagai Y. Cadmium-mediated activation of the HSP90/HSF1 pathway regulated by reactive persulfides/polysulfides. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28115653 DOI: 10.1093/Toxsci/Kfw268  0.105
2010 TAMAI Y, AKIYAMA M, OKAMURA A, MIYANO S. ChemInform Abstract: A Highly Efficient Asymmetric Synthesis of a 4,4-Disubstituted Butan-4- olide by the 1,7-Asymmetric Inductive Addition of Grignard Reagents to γ-Keto Esters. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199239172  0.101
2018 Unoki T, Akiyama M, Kumagai Y, Gonçalves FM, Farina M, da Rocha JBT, Aschner M. Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation. Frontiers in Genetics. 9: 373. PMID 30271424 DOI: 10.3389/Fgene.2018.00373  0.097
2019 Akiyama M, Unoki T, Shinkai Y, Ishii I, Ida T, Akaike T, Yamamoto M, Kumagai Y. Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both. Environmental Health Perspectives. 127: 67002. PMID 31166132 DOI: 10.1289/Ehp4949  0.096
2022 Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y. Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress. Redox Biology. 57: 102514. PMID 36279630 DOI: 10.1016/j.redox.2022.102514  0.096
2022 Tomioka S, Seki N, Sugiura Y, Akiyama M, Uchiyama J, Yamaguchi G, Yakabe K, Ejima R, Hattori K, Kimizuka T, Fujimura Y, Sato H, Gondo M, Ozaki S, Honme Y, et al. Cooperative action of gut-microbiota-accessible carbohydrates improves host metabolic function. Cell Reports. 40: 111087. PMID 35858544 DOI: 10.1016/j.celrep.2022.111087  0.089
1984 TAKANO S, AKIYAMA M, OGASAWARA K. ChemInform Abstract: A NEW α-AMINO ACID SYNTHESIS VIA AN ACETIMIDATE REARRANGEMENT Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198445147  0.086
2022 Uchiyama J, Akiyama M, Hase K, Kumagai Y, Kim YG. Gut microbiota reinforce host antioxidant capacity via the generation of reactive sulfur species. Cell Reports. 38: 110479. PMID 35263581 DOI: 10.1016/j.celrep.2022.110479  0.085
2010 Akiyama M, Zhou M, Sugimoto R, Hongu T, Furuya M, Funakoshi Y, Kato M, Hasegawa H, Kanaho Y. Tissue- and development-dependent expression of the small GTPase Arf6 in mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 3416-35. PMID 21069828 DOI: 10.1002/Dvdy.22481  0.084
2020 Akiyama M, Unoki T, Yoshida E, Ding Y, Yamakawa H, Shinkai Y, Ishii I, Kumagai Y. Repression of mercury accumulation and adverse effects of methylmercury exposure is mediated by cystathionine γ-lyase to produce reactive sulfur species in mouse brain. Toxicology Letters. PMID 32413476 DOI: 10.1016/J.Toxlet.2020.05.007  0.08
2022 Seki N, Kimizuka T, Gondo M, Yamaguchi G, Sugiura Y, Akiyama M, Yakabe K, Uchiyama J, Higashi S, Haneda T, Suematsu M, Hase K, Kim YG. -Tryptophan suppresses enteric pathogen and pathobionts and prevents colitis by modulating microbial tryptophan metabolism. Iscience. 25: 104838. PMID 35996581 DOI: 10.1016/j.isci.2022.104838  0.08
2014 Akiyama M, Hasegawa H, Hongu T, Frohman MA, Harada A, Sakagami H, Kanaho Y. Trans-regulation of oligodendrocyte myelination by neurons through small GTPase Arf6-regulated secretion of fibroblast growth factor-2. Nature Communications. 5: 4744. PMID 25144208 DOI: 10.1038/Ncomms5744  0.074
2022 Unoki T, Akiyama M, Shinkai Y, Kumagai Y, Fujimura M. Spatio-temporal distribution of reactive sulfur species during methylmercury exposure in the rat brain. The Journal of Toxicological Sciences. 47: 31-37. PMID 34987139 DOI: 10.2131/jts.47.31  0.068
2004 Akiyama M, Kaneko Y, Taniguchi Y, Nakajima T, Manita M, Ito T, Saito A, Kurabayashi M. Coronary sinus recordings of double potentials associated with retrograde conduction through left atrioventricular accessory pathways. Journal of Cardiovascular Electrophysiology. 15: 1371-6. PMID 15610281 DOI: 10.1046/j.1540-8167.2004.04422.x  0.063
2015 Akiyama M, Kanaho Y. Physiological functions of the small GTPase Arf6 in the nervous system. Small Gtpases. 6: 160-4. PMID 26291245 DOI: 10.1080/21541248.2015.1043041  0.058
2021 Kimizuka T, Seki N, Yamaguchi G, Akiyama M, Higashi S, Hase K, Kim YG. Amino Acid-Based Diet Prevents Lethal Infectious Diarrhea by Maintaining Body Water Balance in a Murine Infection Model. Nutrients. 13. PMID 34072947 DOI: 10.3390/nu13061896  0.057
2010 Tamai Y, Hattori T, Date M, Koike S, Kamikubo Y, Akiyama M, Seino K, Takayama H, Oyama T, Miyano S. ChemInform Abstract: Pseudo-Macrocyclic Chelation Control in Remote Asymmetric Induction. Highly Efficient 1,7-Asymmetric Inductive Hydride Reduction and Grignard Reaction of γ-Keto Esters of 1,1′-Binaphthalen-2-ols Bearing an Appropriate Oligoether Group Cheminform. 30: no-no. DOI: 10.1002/CHIN.199944041  0.056
2019 Aizawa S, Okada T, Keino-Masu K, Doan TH, Koganezawa T, Akiyama M, Tamaoka A, Masu M. Abnormal Pyramidal Decussation and Bilateral Projection of the Corticospinal Tract Axons in Mice Lacking the Heparan Sulfate Endosulfatases, Sulf1 and Sulf2. Frontiers in Molecular Neuroscience. 12: 333. PMID 32038163 DOI: 10.3389/fnmol.2019.00333  0.056
2010 TAKANO S, AKIYAMA M, SUGIHARA T, OGASAWARA K. ChemInform Abstract: An Efficient Synthesis of Optically Active 4-Benzyloxy-3-hydroxy-1- butyne and Its Cross-Coupling Reaction. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199249130  0.054
2017 Akiyama M, Shinkai Y, Unoki T, Shim I, Ishii I, Kumagai Y. Capture of cadmium by reactive polysulfides attenuates cadmium-induced adaptive responses and hepatotoxicity. Chemical Research in Toxicology. PMID 29116755 DOI: 10.1021/Acs.Chemrestox.7B00278  0.05
2022 Akiyama M, Shinkai Y, Yamakawa H, Kim YG, Kumagai Y. Potentiation of methylmercury toxicity by combined metal exposure: In vitro and in vivo models of a restricted metal exposome. Chemosphere. 134374. PMID 35318019 DOI: 10.1016/j.chemosphere.2022.134374  0.049
2021 Ejima R, Akiyama M, Sato H, Tomioka S, Yakabe K, Kimizuka T, Seki N, Fujimura Y, Hirayama A, Fukuda S, Hase K, Kim YG. Seaweed Dietary Fiber Sodium Alginate Suppresses the Migration of Colonic Inflammatory Monocytes and Diet-Induced Metabolic Syndrome via the Gut Microbiota. Nutrients. 13. PMID 34444972 DOI: 10.3390/nu13082812  0.045
2021 Hattori K, Akiyama M, Seki N, Yakabe K, Hase K, Kim YG. Gut Microbiota Prevents Sugar Alcohol-Induced Diarrhea. Nutrients. 13. PMID 34204751 DOI: 10.3390/nu13062029  0.044
2023 Shinoda Y, Akiyama M, Toyama T. Potential Association between Methylmercury Neurotoxicity and Inflammation. Biological & Pharmaceutical Bulletin. 46: 1162-1168. PMID 37661394 DOI: 10.1248/bpb.b23-00075  0.038
2009 Kaneko Y, Nakajima T, Saito A, Irie T, Ota M, Kato T, Iijima T, Manita M, Ito T, Akiyama M, Taniguchi Y, Kurabayashi M. Discrimination between His-bundle and the right bundle branch during electrophysiologic studies. Pacing and Clinical Electrophysiology : Pace. 32: S72-5. PMID 19250116 DOI: 10.1111/j.1540-8159.2008.02231.x  0.036
2004 Kaneko Y, Taniguchi Y, Nakajima T, Manita M, Ito T, Akiyama M, Kurabayashi M. Myocardial bundles with slow conduction properties are present on the left interventricular septal surface of normal human hearts. Journal of Cardiovascular Electrophysiology. 15: 1010-8. PMID 15363072 DOI: 10.1046/j.1540-8167.2004.04059.x  0.028
2021 Yakabe K, Uchiyama J, Akiyama M, Kim YG. Understanding Host Immunity and the Gut Microbiota Inspires the New Development of Vaccines and Adjuvants. Pharmaceutics. 13. PMID 33530627 DOI: 10.3390/pharmaceutics13020163  0.026
2013 Sakurai K, Akiyama M, Cai B, Scott A, Han BX, Takatoh J, Sigrist M, Arber S, Wang F. The organization of submodality-specific touch afferent inputs in the vibrissa column. Cell Reports. 5: 87-98. PMID 24120861 DOI: 10.1016/j.celrep.2013.08.051  0.025
2020 Akiyama M, Unoki T, Shinkai Y, Ishii I, Ida T, Akaike T, Yamamoto M, Kumagai Y. Erratum: Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both. Environmental Health Perspectives. 128: 69002. PMID 32543884 DOI: 10.1289/EHP7480  0.02
2010 Saito A, Kaneko Y, Nakajima T, Irie T, Ota M, Kato T, Iijima T, Akiyama M, Ito T, Manita M, Kurabayashi M. Left-sided ICD implantation via right-sided venous access in a patient with left hemodialysis fistula. Internal Medicine (Tokyo, Japan). 49: 221-2. PMID 20118598 DOI: JST.JSTAGE/internalmedicine/49.2787  0.014
2022 Osa S, Enoki Y, Miyajima T, Akiyama M, Fujiwara Y, Taguchi K, Kim YG, Matsumoto K. Sciatic denervation-induced skeletal muscle atrophy is associated with persistent inflammation and increased mortality during sepsis. Shock (Augusta, Ga.). PMID 36427072 DOI: 10.1097/SHK.0000000000002053  0.014
2020 Akiyama M, Unoki T, Kumagai Y. Combined exposure to environmental electrophiles enhances cytotoxicity and consumption of persulfide Fundamental Toxicological Sciences. 7: 161-166. DOI: 10.2131/fts.7.161  0.01
2002 Akiyama M, Kaneko Y, Taniguchi Y, Kurabayashi M. Pacemaker syndrome associated with a biventricular pacing system. Journal of Cardiovascular Electrophysiology. 13: 1061-2. PMID 12435200  0.01
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