Year |
Citation |
Score |
2023 |
Wang Y, McNeil P, Abdulazeez R, Pascual M, Johnston SE, Keightley PD, Obbard D. Variation in mutation, recombination, and transposition rates in and . Genome Research. PMID 37037625 DOI: 10.1101/gr.277383.122 |
0.486 |
|
2022 |
López-Cortegano E, Craig RJ, Chebib J, Balogun EJ, Keightley PD. Rates and spectra of de novo structural mutations in . Genome Research. PMID 36617667 DOI: 10.1101/gr.276957.122 |
0.827 |
|
2022 |
Böndel KB, Samuels T, Craig RJ, Ness RW, Colegrave N, Keightley PD. The distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii inferred using frequency changes under experimental evolution. Plos Genetics. 18: e1009840. PMID 35704655 DOI: 10.1371/journal.pgen.1009840 |
0.757 |
|
2021 |
López-Cortegano E, Craig RJ, Chebib J, Samuels T, Morgan AD, Kraemer SA, Böndel KB, Ness RW, Colegrave N, Keightley PD. De novo mutation rate variation and its determinants in Chlamydomonas. Molecular Biology and Evolution. PMID 33950243 DOI: 10.1093/molbev/msab140 |
0.839 |
|
2021 |
Craig RJ, Hasan AR, Ness RW, Keightley PD. Comparative genomics of Chlamydomonas. The Plant Cell. PMID 33793842 DOI: 10.1093/plcell/koab026 |
0.76 |
|
2020 |
Chebib J, Jackson BC, López-Cortegano E, Tautz D, Keightley PD. Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site. Heredity. PMID 32868871 DOI: 10.1038/s41437-020-00361-1 |
0.795 |
|
2019 |
Craig RJ, Böndel KB, Arakawa K, Nakada T, Ito T, Bell G, Colegrave N, Keightley PD, Ness RW. Patterns of population structure and complex haplotype sharing among field isolates of the green alga Chlamydomonas reinhardtii. Molecular Ecology. PMID 31338894 DOI: 10.1111/Mec.15193 |
0.694 |
|
2019 |
Böndel KB, Kraemer SA, Samuels T, McClean D, Lachapelle J, Ness RW, Colegrave N, Keightley PD. Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii. Plos Biology. 17: e3000192. PMID 31242179 DOI: 10.1371/Journal.Pbio.3000192 |
0.774 |
|
2018 |
Booker TR, Keightley PD. Understanding the factors that shape patterns of nucleotide diversity in the house mouse genome. Molecular Biology and Evolution. PMID 30295866 DOI: 10.1093/molbev/msy188 |
0.478 |
|
2018 |
Katju V, Packard LB, Keightley PD. Fitness decline under osmotic stress in Caenorhabditis elegans populations subjected to spontaneous mutation accumulation at varying population sizes. Evolution; International Journal of Organic Evolution. PMID 29513384 DOI: 10.1111/Evo.13463 |
0.349 |
|
2017 |
Booker TR, Jackson BC, Keightley PD. Detecting positive selection in the genome. Bmc Biology. 15: 98. PMID 29084517 DOI: 10.1186/s12915-017-0434-y |
0.334 |
|
2017 |
Kraemer S, Böndel KB, Ness RW, Keightley PD, Colegrave N. Fitness change in relation to mutation number in spontaneous mutation accumulation lines of Chlamydomonas reinhardtii. Evolution; International Journal of Organic Evolution. PMID 28884790 DOI: 10.1111/Evo.13360 |
0.472 |
|
2017 |
Booker TR, Ness RW, Keightley PD. The Recombination Landscape in Wild House Mice Inferred Using Population Genomic Data. Genetics. PMID 28751421 DOI: 10.1534/genetics.117.300063 |
0.703 |
|
2017 |
Konrad A, Thompson O, Waterston RH, Moerman DG, Keightley PD, Bergthorsson U, Katju V. Article: Discoveries. Molecular Biology and Evolution. PMID 28087770 DOI: 10.1093/Molbev/Msx051 |
0.503 |
|
2016 |
Keightley PD, Campos JL, Booker TR, Charlesworth B. Inferring the Frequency Spectrum of Derived Variants to Quantify Adaptive Molecular Evolution in Protein-Coding Genes of Drosophila melanogaster. Genetics. PMID 27098912 DOI: 10.1534/Genetics.116.188102 |
0.45 |
|
2015 |
Kraemer SA, Morgan AD, Ness RW, Keightley PD, Colegrave N. Fitness effects of new mutations in Chlamydomonas reinhardtii across two stress gradients. Journal of Evolutionary Biology. PMID 26663473 DOI: 10.1111/Jeb.12807 |
0.708 |
|
2015 |
Ness RW, Kraemer SA, Colegrave N, Keightley PD. Direct estimate of the spontaneous mutation rate uncovers the effects of drift and recombination in the Chlamydomonas reinhardtii plastid genome. Molecular Biology and Evolution. PMID 26615203 DOI: 10.1093/Molbev/Msv272 |
0.777 |
|
2015 |
Caballero A, Tenesa A, Keightley PD. The Nature of Genetic Variation for Complex Traits Revealed by GWAS and Regional Heritability Mapping Analyses. Genetics. PMID 26482794 DOI: 10.1534/genetics.115.177220 |
0.389 |
|
2015 |
Wiberg RA, Halligan DL, Ness RW, Necsulea A, Kaessmann H, Keightley PD. Assessing Recent Selection and Functionality at Long Noncoding RNA Loci in the Mouse Genome. Genome Biology and Evolution. 7: 2432-44. PMID 26272717 DOI: 10.1093/gbe/evv155 |
0.808 |
|
2015 |
Ness RW, Morgan AD, Vasanthakrishnan RB, Colegrave N, Keightley PD. Extensive de novo mutation rate variation between individuals and across the genome of Chlamydomonas reinhardtii. Genome Research. 25: 1739-49. PMID 26260971 DOI: 10.1101/Gr.191494.115 |
0.805 |
|
2015 |
Deinum EE, Halligan DL, Ness RW, Zhang YH, Cong L, Zhang JX, Keightley PD. Recent Evolution in Rattus norvegicus Is Shaped by Declining Effective Population Size. Molecular Biology and Evolution. PMID 26037536 DOI: 10.1093/molbev/msv126 |
0.826 |
|
2015 |
Keightley PD, Pinharanda A, Ness RW, Simpson F, Dasmahapatra KK, Mallet J, Davey JW, Jiggins CD. Estimation of the spontaneous mutation rate in Heliconius melpomene. Molecular Biology and Evolution. 32: 239-43. PMID 25371432 DOI: 10.1093/Molbev/Msu302 |
0.764 |
|
2015 |
Katju V, Packard LB, Bu L, Keightley PD, Bergthorsson U. Fitness decline in spontaneous mutation accumulation lines of Caenorhabditis elegans with varying effective population sizes. Evolution; International Journal of Organic Evolution. 69: 104-16. PMID 25338758 DOI: 10.1111/Evo.12554 |
0.4 |
|
2015 |
Keightley PD, Pinharanda A, Ness RW, Simpson F, Dasmahapatra KK, Mallet J, Davey JW, Jiggins CD. Estimation of the Spontaneous Mutation Rate in Heliconius melpomene Molecular Biology and Evolution. 32: 239-243. DOI: 10.1093/molbev/msu302 |
0.742 |
|
2014 |
Morgan AD, Ness RW, Keightley PD, Colegrave N. Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii. Evolution; International Journal of Organic Evolution. 68: 2589-602. PMID 24826801 DOI: 10.1111/evo.12448 |
0.777 |
|
2014 |
Kousathanas A, Halligan DL, Keightley PD. Faster-X adaptive protein evolution in house mice. Genetics. 196: 1131-43. PMID 24361937 DOI: 10.1534/Genetics.113.158246 |
0.788 |
|
2014 |
Keightley PD, Ness RW, Halligan DL, Haddrill PR. Estimation of the spontaneous mutation rate per nucleotide site in a Drosophila melanogaster full-sib family. Genetics. 196: 313-20. PMID 24214343 DOI: 10.1534/genetics.113.158758 |
0.839 |
|
2013 |
Halligan DL, Kousathanas A, Ness RW, Harr B, Eöry L, Keane TM, Adams DJ, Keightley PD. Contributions of protein-coding and regulatory change to adaptive molecular evolution in murid rodents. Plos Genetics. 9: e1003995. PMID 24339797 DOI: 10.1371/Journal.Pgen.1003995 |
0.8 |
|
2013 |
Kousathanas A, Keightley PD. A comparison of models to infer the distribution of fitness effects of new mutations. Genetics. 193: 1197-208. PMID 23341416 DOI: 10.1534/Genetics.112.148023 |
0.762 |
|
2012 |
Ness RW, Zhang YH, Cong L, Wang Y, Zhang JX, Keightley PD. Nuclear gene variation in wild brown rats. G3 (Bethesda, Md.). 2: 1661-4. PMID 23275888 DOI: 10.1534/g3.112.004713 |
0.697 |
|
2012 |
Hartfield M, Otto SP, Keightley PD. The maintenance of obligate sex in finite, structured populations subject to recurrent beneficial and deleterious mutation Evolution. 66: 3658-3669. PMID 23206126 DOI: 10.1111/J.1558-5646.2012.01733.X |
0.728 |
|
2012 |
Ness RW, Morgan AD, Colegrave N, Keightley PD. Estimate of the spontaneous mutation rate in Chlamydomonas reinhardtii. Genetics. 192: 1447-54. PMID 23051642 DOI: 10.1534/genetics.112.145078 |
0.773 |
|
2012 |
Hartfield M, Keightley PD. Current hypotheses for the evolution of sex and recombination. Integrative Zoology. 7: 192-209. PMID 22691203 DOI: 10.1111/J.1749-4877.2012.00284.X |
0.741 |
|
2012 |
Lesecque Y, Keightley PD, Eyre-Walker A. A resolution of the mutation load paradox in humans. Genetics. 191: 1321-30. PMID 22661324 DOI: 10.1534/Genetics.112.140343 |
0.464 |
|
2012 |
Gossmann TI, Keightley PD, Eyre-Walker A. The effect of variation in the effective population size on the rate of adaptive molecular evolution in eukaryotes. Genome Biology and Evolution. 4: 658-67. PMID 22436998 DOI: 10.1093/Gbe/Evs027 |
0.331 |
|
2012 |
Keightley PD. Rates and fitness consequences of new mutations in humans. Genetics. 190: 295-304. PMID 22345605 DOI: 10.1534/genetics.111.134668 |
0.36 |
|
2012 |
Keightley PD, Eyre-Walker A. Estimating the rate of adaptive molecular evolution when the evolutionary divergence between species is small. Journal of Molecular Evolution. 74: 61-8. PMID 22327123 DOI: 10.1007/S00239-012-9488-1 |
0.436 |
|
2011 |
Schneider A, Charlesworth B, Eyre-Walker A, Keightley PD. A method for inferring the rate of occurrence and fitness effects of advantageous mutations. Genetics. 189: 1427-37. PMID 21954160 DOI: 10.1534/Genetics.111.131730 |
0.486 |
|
2011 |
Keightley PD, Halligan DL. Inference of site frequency spectra from high-throughput sequence data: quantification of selection on nonsynonymous and synonymous sites in humans. Genetics. 188: 931-40. PMID 21596896 DOI: 10.1534/genetics.111.128355 |
0.762 |
|
2011 |
Halligan DL, Oliver F, Guthrie J, Stemshorn KC, Harr B, Keightley PD. Positive and negative selection in murine ultraconserved noncoding elements. Molecular Biology and Evolution. 28: 2651-60. PMID 21478460 DOI: 10.1093/molbev/msr093 |
0.787 |
|
2011 |
Keightley PD, Eöry L, Halligan DL, Kirkpatrick M. Inference of mutation parameters and selective constraint in mammalian coding sequences by approximate Bayesian computation. Genetics. 187: 1153-61. PMID 21288873 DOI: 10.1534/Genetics.110.124073 |
0.833 |
|
2011 |
Kousathanas A, Oliver F, Halligan DL, Keightley PD. Positive and negative selection on noncoding DNA close to protein-coding genes in wild house mice. Molecular Biology and Evolution. 28: 1183-91. PMID 21059791 DOI: 10.1093/Molbev/Msq299 |
0.812 |
|
2010 |
Keightley PD, Eyre-Walker A. What can we learn about the distribution of fitness effects of new mutations from DNA sequence data? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 1187-93. PMID 20308093 DOI: 10.1098/Rstb.2009.0266 |
0.462 |
|
2010 |
Hartfield M, Otto SP, Keightley PD. The role of advantageous mutations in enhancing the evolution of a recombination modifier Genetics. 184: 1153-1164. PMID 20139345 DOI: 10.1534/Genetics.109.112920 |
0.79 |
|
2010 |
Halligan DL, Oliver F, Eyre-Walker A, Harr B, Keightley PD. Evidence for pervasive adaptive protein evolution in wild mice. Plos Genetics. 6: e1000825. PMID 20107605 DOI: 10.1371/Journal.Pgen.1000825 |
0.739 |
|
2010 |
Eory L, Halligan DL, Keightley PD. Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes. Molecular Biology and Evolution. 27: 177-92. PMID 19759235 DOI: 10.1093/Molbev/Msp219 |
0.838 |
|
2009 |
Marion de Procé S, Halligan DL, Keightley PD, Charlesworth B. Patterns of DNA-sequence divergence between Drosophila miranda and D. pseudoobscura. Journal of Molecular Evolution. 69: 601-11. PMID 19859648 DOI: 10.1007/s00239-009-9298-2 |
0.735 |
|
2009 |
Eyre-Walker A, Keightley PD. Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change. Molecular Biology and Evolution. 26: 2097-108. PMID 19535738 DOI: 10.1093/Molbev/Msp119 |
0.436 |
|
2009 |
Keightley PD, Trivedi U, Thomson M, Oliver F, Kumar S, Blaxter ML. Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines. Genome Research. 19: 1195-201. PMID 19439516 DOI: 10.1101/Gr.091231.109 |
0.472 |
|
2009 |
Keightley PD, Halligan DL. Analysis and implications of mutational variation. Genetica. 136: 359-69. PMID 18663587 DOI: 10.1007/s10709-008-9304-4 |
0.789 |
|
2009 |
Halligan DL, Keightley PD. Spontaneous Mutation Accumulation Studies in Evolutionary Genetics Annual Review of Ecology, Evolution, and Systematics. 40: 151-172. DOI: 10.1146/ANNUREV.ECOLSYS.39.110707.173437 |
0.76 |
|
2008 |
Gaffney DJ, Keightley PD. Effect of the assignment of ancestral CpG state on the estimation of nucleotide substitution rates in mammals. Bmc Evolutionary Biology. 8: 265. PMID 18826599 DOI: 10.1186/1471-2148-8-265 |
0.679 |
|
2008 |
Haag-Liautard C, Coffey N, Houle D, Lynch M, Charlesworth B, Keightley PD. Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster. Plos Biology. 6: e204. PMID 18715119 DOI: 10.1371/Journal.Pbio.0060204 |
0.497 |
|
2008 |
Haag-Liautard C, Dorris M, Maside X, MacAskill S, Halligan DL, Houle D, Charlesworth B, Keightley PD. Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila (Nature (2007) 445, (82-85)) Nature. 453: 128. DOI: 10.1038/nature06946 |
0.786 |
|
2007 |
Keightley PD, Eyre-Walker A. Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequencies. Genetics. 177: 2251-61. PMID 18073430 DOI: 10.1534/Genetics.107.080663 |
0.409 |
|
2007 |
Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, ... ... Keightley PD, et al. Evolution of genes and genomes on the Drosophila phylogeny. Nature. 450: 203-18. PMID 17994087 DOI: 10.1038/Nature06341 |
0.741 |
|
2007 |
Wang J, Keightley PD, Halligan DL. Effect of divergence time and recombination rate on molecular evolution of Drosophila INE-1 transposable elements and other candidates for neutrally evolving sites. Journal of Molecular Evolution. 65: 627-39. PMID 17896069 DOI: 10.1007/s00239-007-9028-6 |
0.769 |
|
2007 |
Eyre-Walker A, Keightley PD. The distribution of fitness effects of new mutations. Nature Reviews. Genetics. 8: 610-8. PMID 17637733 DOI: 10.1038/Nrg2146 |
0.475 |
|
2007 |
Haag-Liautard C, Dorris M, Maside X, Macaskill S, Halligan DL, Houle D, Charlesworth B, Keightley PD. Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila. Nature. 445: 82-5. PMID 17203060 DOI: 10.1038/Nature05388 |
0.811 |
|
2006 |
Gaffney DJ, Keightley PD. Genomic selective constraints in murid noncoding DNA. Plos Genetics. 2: e204. PMID 17166057 DOI: 10.1371/journal.pgen.0020204 |
0.728 |
|
2006 |
Keightley PD, Otto SP. Interference among deleterious mutations favours sex and recombination in finite populations Nature. 443: 89-92. PMID 16957730 DOI: 10.1038/nature05049 |
0.415 |
|
2006 |
Halligan DL, Keightley PD. Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison. Genome Research. 16: 875-84. PMID 16751341 DOI: 10.1101/gr.5022906 |
0.757 |
|
2006 |
Keightley PD, Lercher MJ, Eyre-Walker A. Understanding the degradation of hominid gene control. Plos Computational Biology. 2: e19; author reply e2. PMID 16604186 DOI: 10.1371/Journal.Pcbi.0020019 |
0.366 |
|
2005 |
Keightley PD, Kryukov GV, Sunyaev S, Halligan DL, Gaffney DJ. Evolutionary constraints in conserved nongenic sequences of mammals. Genome Research. 15: 1373-8. PMID 16204190 DOI: 10.1101/Gr.3942005 |
0.856 |
|
2005 |
Gaffney DJ, Keightley PD. The scale of mutational variation in the murid genome. Genome Research. 15: 1086-94. PMID 16024822 DOI: 10.1101/gr.3895005 |
0.749 |
|
2005 |
Keightley PD, Lercher MJ, Eyre-Walker A. Evidence for widespread degradation of gene control regions in hominid genomes. Plos Biology. 3: e42. PMID 15678168 DOI: 10.1371/Journal.Pbio.0030042 |
0.426 |
|
2005 |
Keightley PD, Charlesworth B. Genetic instability of C. elegans comes naturally. Trends in Genetics : Tig. 21: 67-70. PMID 15661349 DOI: 10.1016/j.tig.2004.11.015 |
0.487 |
|
2004 |
Wesche PL, Gaffney DJ, Keightley PD. DNA sequence error rates in Genbank records estimated using the mouse genome as a reference. Dna Sequence : the Journal of Dna Sequencing and Mapping. 15: 362-4. PMID 15621661 DOI: 10.1080/10425170400008972 |
0.666 |
|
2004 |
Gantenbein B, Keightley PD. Rates of molecular evolution in nuclear genes of east Mediterranean scorpions. Evolution; International Journal of Organic Evolution. 58: 2486-97. PMID 15612292 |
0.353 |
|
2004 |
Gaffney DJ, Keightley PD. Unexpected conserved non-coding DNA blocks in mammals. Trends in Genetics : Tig. 20: 332-7. PMID 15262402 DOI: 10.1016/j.tig.2004.06.011 |
0.661 |
|
2004 |
Keightley PD. Comparing analysis methods for mutation-accumulation data. Genetics. 167: 551-3. PMID 15166177 |
0.314 |
|
2004 |
Halligan DL, Eyre-Walker A, Andolfatto P, Keightley PD. Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila. Genome Research. 14: 273-9. PMID 14762063 DOI: 10.1101/Gr.1329204 |
0.783 |
|
2003 |
Halligan DL, Peters AD, Keightley PD. Estimating numbers of EMS-induced mutations affecting life history traits in Caenorhabditis elegans in crosses between inbred sublines. Genetical Research. 82: 191-205. PMID 15134198 |
0.772 |
|
2003 |
Keightley PD, Gaffney DJ. Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents. Proceedings of the National Academy of Sciences of the United States of America. 100: 13402-6. PMID 14597721 DOI: 10.1073/pnas.2233252100 |
0.758 |
|
2003 |
Keightley PD, Lynch M. Toward a realistic model of mutations affecting fitness Evolution. 57: 683-685. PMID 12703958 DOI: 10.1111/J.0014-3820.2003.Tb01561.X |
0.377 |
|
2003 |
Halligan DL, Keightley PD. How many lethal alleles? Trends in Genetics : Tig. 19: 57-9. PMID 12547508 DOI: 10.1016/S0168-9525(02)00045-8 |
0.704 |
|
2002 |
Eyre-Walker A, Keightley PD, Smith NG, Gaffney D. Quantifying the slightly deleterious mutation model of molecular evolution. Molecular Biology and Evolution. 19: 2142-9. PMID 12446806 DOI: 10.1093/Oxfordjournals.Molbev.A004039 |
0.729 |
|
2002 |
Azevedo RB, Keightley PD, Laurén-Määttä C, Vassilieva LL, Lynch M, Leroi AM. Spontaneous mutational variation for body size in Caenorhabditis elegans. Genetics. 162: 755-65. PMID 12399386 |
0.438 |
|
2001 |
Keightley PD, Eyre-Walker A. Response to Kondrashov. Trends in Genetics : Tig. 17: 77-8. PMID 11173115 DOI: 10.1016/S0168-9525(00)02177-6 |
0.41 |
|
2000 |
Keightley PD, Eyre-Walker A. Deleterious mutations and the evolution of sex. Science (New York, N.Y.). 290: 331-3. PMID 11030650 DOI: 10.1126/Science.290.5490.331 |
0.481 |
|
1999 |
Davies EK, Peters AD, Keightley PD. High frequency of cryptic deleterious mutations in Caenorhabditis elegans. Science (New York, N.Y.). 285: 1748-51. PMID 10481013 DOI: 10.1126/SCIENCE.285.5434.1748 |
0.429 |
|
1999 |
Eyre-Walker A, Keightley PD. High genomic deleterious mutation rates in hominids. Nature. 397: 344-7. PMID 9950425 DOI: 10.1038/16915 |
0.536 |
|
1999 |
Fry JD, Keightley PD, Heinsohn SL, Nuzhdin SV. New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 96: 574-9. PMID 9892675 DOI: 10.1073/pnas.96.2.574 |
0.483 |
|
1999 |
KEIGHTLEY PD. Analysis of mutation accumulation experiments: response to
Deng, Li and Li Genetical Research. 74: 87-91. DOI: 10.1017/S0016672399003894 |
0.387 |
|
1998 |
Keightley PD, Caballero A, García-Dorado A. Population genetics: surviving under mutation pressure. Current Biology : Cb. 8: R235-7. PMID 9545191 DOI: 10.1016/S0960-9822(98)70148-4 |
0.377 |
|
1998 |
Rance KA, Hill WG, Keightley PD. Mapping quantitative trait loci for body weight on the X chromosome in mice. I. Analysis of a reciprocal F2 population. Genetical Research. 70: 117-24. PMID 9449188 DOI: 10.1017/S0016672397002917 |
0.466 |
|
1997 |
Keightley PD, Caballero A. Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 94: 3823-7. PMID 9108062 DOI: 10.1073/PNAS.94.8.3823 |
0.499 |
|
1995 |
Caballero A, Keightley PD, Hill WG. Accumulation of mutations affecting body weight in inbred mouse lines. Genetical Research. 65: 145-9. PMID 7781996 DOI: 10.1017/S0016672300033152 |
0.581 |
|
1993 |
Keightley PD, Mackay TF, Caballero A. Accounting for bias in estimates of the rate of polygenic mutation. Proceedings. Biological Sciences. 253: 291-6. PMID 8234366 DOI: 10.1098/rspb.1993.0116 |
0.448 |
|
1991 |
Keightley PD. Genetic variance and fixation probabilities at quantitative trait loci in mutation-selection balance Genetical Research. 58: 139-144. DOI: 10.1017/S0016672300029797 |
0.454 |
|
1991 |
Caballero A, Keightley PD, Hill WG. Strategies for increasing fixation probabilities of recessive mutations Genetical Research. 58: 129-138. DOI: 10.1017/S0016672300029785 |
0.551 |
|
1989 |
Keightley PD, Hill WG. Quantitative genetic variability maintained by mutation-stabilizing selection balance: sampling variation and response to subsequent directional selection. Genetical Research. 54: 45-57. PMID 2806906 DOI: 10.1017/S0016672300028366 |
0.541 |
|
1988 |
Keightley PD, Hill WG. Quantitative genetic variability maintained by mutation-stabilizing selection balance in finite populations. Genetical Research. 52: 33-43. PMID 3181758 DOI: 10.1017/S0016672300027282 |
0.593 |
|
1984 |
Keightley PD, Hill WG. Effects of linkage on response to directional selection from new mutations. Genetical Research. 42: 193-206. PMID 6667853 DOI: 10.1017/S0016672300021650 |
0.606 |
|
Low-probability matches (unlikely to be authored by this person) |
2022 |
Johri P, Aquadro CF, Beaumont M, Charlesworth B, Excoffier L, Eyre-Walker A, Keightley PD, Lynch M, McVean G, Payseur BA, Pfeifer SP, Stephan W, Jensen JD. Recommendations for improving statistical inference in population genomics. Plos Biology. 20: e3001669. PMID 35639797 DOI: 10.1371/journal.pbio.3001669 |
0.299 |
|
2005 |
Charlesworth B, Keightley P, Visscher P. Introduction: Population genetics, quantitative genetics and animal improvement: Papers in honour of William (Bill) Hill Philosophical Transactions of the Royal Society B: Biological Sciences. 360: 1365-1366. DOI: 10.1098/Rstb.2005.1678 |
0.282 |
|
2004 |
Keightley PD, Johnson T. MCALIGN: stochastic alignment of noncoding DNA sequences based on an evolutionary model of sequence evolution. Genome Research. 14: 442-50. PMID 14993209 DOI: 10.1101/gr.1571904 |
0.273 |
|
2005 |
Marais G, Nouvellet P, Keightley PD, Charlesworth B. Intron size and exon evolution in Drosophila. Genetics. 170: 481-5. PMID 15781704 DOI: 10.1534/genetics.104.037333 |
0.271 |
|
2007 |
Guo X, Wang Y, Keightley PD, Fan L. Patterns of selective constraints in noncoding DNA of rice. Bmc Evolutionary Biology. 7: 208. PMID 17976238 DOI: 10.1186/1471-2148-7-208 |
0.271 |
|
1994 |
Keightley PD, Bulfield G. Detection of quantitative trait loci from frequency changes of marker alleles under selection. Genetical Research. 62: 195-203. PMID 8157171 DOI: 10.1017/S0016672300031906 |
0.266 |
|
2018 |
Keightley PD, Jackson BC. Inferring the Probability of the Derived the Ancestral Allelic State at a Polymorphic Site. Genetics. PMID 29769282 DOI: 10.1534/genetics.118.301120 |
0.264 |
|
2002 |
Barton NH, Keightley PD. Understanding quantitative genetic variation. Nature Reviews. Genetics. 3: 11-21. PMID 11823787 DOI: 10.1038/Nrg700 |
0.258 |
|
2005 |
Oliver F, Christians JK, Liu X, Rhind S, Verma V, Davison C, Brown SD, Denny P, Keightley PD. Regulatory variation at glypican-3 underlies a major growth QTL in mice. Plos Biology. 3: e135. PMID 15799711 DOI: 10.1371/journal.pbio.0030135 |
0.247 |
|
1998 |
Nuzhdin SV, Keightley PD, Pasyukova EG, Morozova EA. Mapping quantitative trait loci affecting sternopleural bristle number in Drosophila melanogaster using changes of marker allele frequencies in divergently selected lines. Genetical Research. 72: 79-91. PMID 9883095 DOI: 10.1017/S001667239800336X |
0.243 |
|
1996 |
Heath SC, Bulfield G, Thompson R, Keightley PD. Rates of change of genetic parameters of body weight in selected mouse lines. Genetical Research. 66: 19-25. PMID 8575666 DOI: 10.1017/S0016672300034352 |
0.24 |
|
2006 |
Wang J, Keightley PD, Johnson T. MCALIGN2: faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution. Bmc Bioinformatics. 7: 292. PMID 16762073 DOI: 10.1186/1471-2105-7-292 |
0.238 |
|
2005 |
Christians JK, Keightley PD. Behavioural genetics: finding genes that cause complex trait variation. Current Biology : Cb. 15: R19-21. PMID 15649345 DOI: 10.1016/j.cub.2004.12.013 |
0.235 |
|
1993 |
Nuzhdin SV, Keightley PD, Pasyukova EG. The use of retrotransposons as markers for mapping genes responsible for fitness differences between related Drosophila melanogaster strains. Genetical Research. 62: 125-31. PMID 8276230 DOI: 10.1017/S0016672300031712 |
0.23 |
|
2002 |
Christians JK, Keightley PD. Genetic architecture: dissecting the genetic basis of phenotypic variation. Current Biology : Cb. 12: R415-6. PMID 12123589 |
0.218 |
|
1995 |
Keightley PD. Quantitative genetics. Loci with large effects. Current Biology : Cb. 5: 485-7. PMID 7583095 DOI: 10.1016/S0960-9822(95)00098-4 |
0.213 |
|
1996 |
Keightley PD. Metabolic models of selection response. Journal of Theoretical Biology. 182: 311-6. PMID 8944163 DOI: 10.1006/JTBI.1996.0169 |
0.212 |
|
1989 |
Keightley P. Life's formula Nature. 342: 490-491. DOI: 10.1038/342490A0 |
0.207 |
|
2006 |
Christians JK, Hoeflich A, Keightley PD. PAPPA2, an enzyme that cleaves an insulin-like growth-factor-binding protein, is a candidate gene for a quantitative trait locus affecting body size in mice. Genetics. 173: 1547-53. PMID 16702428 DOI: 10.1534/genetics.106.057513 |
0.204 |
|
2004 |
Christians JK, Keightley PD. Fine mapping of a murine growth locus to a 1.4-cM region and resolution of linked QTL. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 482-91. PMID 15181540 DOI: 10.1007/s00335-004-3046-0 |
0.198 |
|
1999 |
Keightley PD, Morris KH, Ishikawa A, Falconer VM, Oliver F. Test of candidate gene--quantitative trait locus association applied to fatness in mice. Heredity. 630-7. PMID 9885188 DOI: 10.1046/j.1365-2540.1998.00450.x |
0.192 |
|
2002 |
Millar CB, Guy J, Sansom OJ, Selfridge J, MacDougall E, Hendrich B, Keightley PD, Bishop SM, Clarke AR, Bird A. Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice. Science (New York, N.Y.). 297: 403-5. PMID 12130785 DOI: 10.1126/Science.1073354 |
0.192 |
|
2003 |
Christians JK, Bingham VK, Oliver FK, Heath TT, Keightley PD. Characterization of a QTL affecting skeletal size in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 175-83. PMID 12647240 DOI: 10.1007/s00335-002-3041-2 |
0.19 |
|
1999 |
Morris KH, Ishikawa A, Keightley PD. Quantitative trait loci for growth traits in C57BL/6J x DBA/2J mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 225-8. PMID 10051315 DOI: 10.1007/s003359900977 |
0.188 |
|
2001 |
Liu X, Oliver F, Brown SD, Denny P, Keightley PD. High-resolution quantitative trait locus mapping for body weight in mice by recombinant progeny testing. Genetical Research. 77: 191-7. PMID 11355574 DOI: 10.1017/S0016672301004943 |
0.186 |
|
2000 |
Johnson T, Keightley PD. Quantitative genetics: Resolving wing shape genes. Current Biology : Cb. 10: R113-5. PMID 10679319 DOI: 10.1016/S0960-9822(00)00306-7 |
0.178 |
|
2018 |
Bell D, Routley N, Whiteman G, Keightley P. The development of a smaller Asay foil diagnostic Bulletin of the American Physical Society. DOI: 10.1063/1.5044843 |
0.172 |
|
2001 |
Liu X, Bünger L, Keightley PD. Characterization of a major X-linked quantitative trait locus influencing body weight of mice. The Journal of Heredity. 92: 355-7. PMID 11535651 DOI: 10.1093/JHERED/92.4.355 |
0.164 |
|
1996 |
Kay SJ, Keightley PD. Low rates of proviral integration in SWR/J-RF/J hybrid mice. Genetical Research. 66: 45-52. PMID 8575669 DOI: 10.1017/S0016672300034388 |
0.161 |
|
1998 |
Rance KA, Heath SC, Keightley PD. Mapping quantitative trait loci for body weight on the X chromosome in mice. II. Analysis of congenic backcrosses. Genetical Research. 70: 125-33. PMID 9449189 DOI: 10.1017/S0016672397002929 |
0.146 |
|
2016 |
Puckett EE, Park J, Combs M, Blum MJ, Bryant JE, Caccone A, Costa F, Deinum EE, Esther A, Himsworth CG, Keightley PD, Ko A, Lundkvist Å, McElhinney LM, Morand S, et al. Global population divergence and admixture of the brown rat (Rattus norvegicus). Proceedings. Biological Sciences. 283. PMID 27798305 DOI: 10.1098/Rspb.2016.1762 |
0.141 |
|
2005 |
Stylianou IM, Clinton M, Keightley PD, Pritchard C, Tymowska-Lalanne Z, Bünger L, Horvat S. Microarray gene expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways. Physiological Genomics. 20: 224-32. PMID 15598878 DOI: 10.1152/physiolgenomics.00183.2004 |
0.133 |
|
2000 |
Keightley PD, Knott SA. Testing the correspondence between map positions of quantitative trait loci. Genetical Research. 74: 323-8. PMID 10689808 DOI: 10.1017/S0016672399004176 |
0.121 |
|
2004 |
Stylianou IM, Christians JK, Keightley PD, Bünger L, Clinton M, Bulfield G, Horvat S. Genetic complexity of an obesity QTL ( Fob3) revealed by detailed genetic mapping. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 472-81. PMID 15181539 DOI: 10.1007/s00335-004-3039-z |
0.113 |
|
2000 |
Horvat S, Bünger L, Falconer VM, Mackay P, Law A, Bulfield G, Keightley PD. Mapping of obesity QTLs in a cross between mouse lines divergently selected on fat content. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 2-7. PMID 10602985 DOI: 10.1007/s003350010002 |
0.09 |
|
2022 |
Keightley PD. William G. Hill (1940-2021). Nature Ecology & Evolution. 6: 344-345. PMID 35165393 DOI: 10.1038/s41559-022-01687-1 |
0.017 |
|
1995 |
Keightley PD. Chewing the fat. Nature Genetics. 10: 125-6. PMID 7663503 DOI: 10.1038/NG0695-125 |
0.012 |
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