William M. Miller - Publications

Affiliations: 
Chemical and Biological Engineering Northwestern University, Evanston, IL 

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Martinez AF, Miller WM. Enabling Large-Scale ex vivo Production of Megakaryocytes from CD34 Cells Using Gas-Permeable Surfaces. Stem Cells Translational Medicine. PMID 30848565 DOI: 10.1002/Sctm.18-0160  0.435
2017 Uzarski JS, DiVito MD, Wertheim JA, Miller WM. Essential design considerations for the resazurin reduction assay to noninvasively quantify cell expansion within perfused extracellular matrix scaffolds. Biomaterials. 129: 163-175. PMID 28343003 DOI: 10.1016/J.Biomaterials.2017.02.015  0.399
2016 Schlinker AC, Duncan MT, DeLuca TA, Whitehead DC, Miller WM. Megakaryocyte Polyploidization and Proplatelet Formation in Low-Attachment Conditions. Biochemical Engineering Journal. 111: 24-33. PMID 27087780 DOI: 10.1016/J.Bej.2016.03.001  0.785
2016 Duncan MT, DeLuca TA, Kuo HY, Yi M, Mrksich M, Miller WM. SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation. Experimental Cell Research. PMID 27086164 DOI: 10.1016/J.Yexcr.2016.04.010  0.395
2016 Martinez A, McMahon R, Jenkins K, Miller WM. Using Computational Fluid Dynamics (CFD) to Enhance Ex Vivo Platelet Production Via Shear Forces within Microfluidic Bioreactors Blood. 128: 1352-1352. DOI: 10.1182/Blood.V128.22.1352.1352  0.334
2015 Uzarski JS, Su J, Xie Y, Zhang ZJ, Ward HH, Wandinger-Ness A, Miller WM, Wertheim JA. Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development. Journal of Visualized Experiments : Jove. PMID 26327609 DOI: 10.3791/53271  0.308
2015 Uzarski JS, Bijonowski BM, Wang B, Ward HH, Wandinger-Ness A, Miller WM, Wertheim JA. Dual-purpose bioreactors to monitor non-invasive physical and biochemical markers of kidney and liver scaffold recellularization. Tissue Engineering. Part C, Methods. PMID 25929317 DOI: 10.1089/Ten.Tec.2014.0665  0.377
2015 Finkielsztein A, Schlinker AC, Zhang L, Miller WM, Datta SK. Human megakaryocyte progenitors derived from hematopoietic stem cells of normal individuals are MHC class II-expressing professional APC that enhance Th17 and Th1/Th17 responses. Immunology Letters. 163: 84-95. PMID 25454068 DOI: 10.1016/J.Imlet.2014.11.013  0.78
2015 Caralt M, Uzarski JS, Iacob S, Obergfell KP, Berg N, Bijonowski BM, Kiefer KM, Ward HH, Wandinger-Ness A, Miller WM, Zhang ZJ, Abecassis MM, Wertheim JA. Optimization and critical evaluation of decellularization strategies to develop renal extracellular matrix scaffolds as biological templates for organ engineering and transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15: 64-75. PMID 25403742 DOI: 10.1111/Ajt.12999  0.367
2015 Schlinker AC, Radwanski K, Wegener C, Min K, Miller WM. Separation of in-vitro-derived megakaryocytes and platelets using spinning-membrane filtration. Biotechnology and Bioengineering. 112: 788-800. PMID 25312394 DOI: 10.1002/Bit.25477  0.784
2015 Koguchi Y, Meeuwsen T, Gonzalez I, Miller W, Bahjat KS. A scalable platform for clinical immunophenotyping: assay design and quality control for high complexity flow cytometry Journal For Immunotherapy of Cancer. 3: 251. DOI: 10.1186/2051-1426-3-S2-P251  0.311
2014 Duncan MT, Shin S, Wu JJ, Mays Z, Weng S, Bagheri N, Miller WM, Shea LD. Dynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiation. Biotechnology and Bioengineering. 111: 2082-94. PMID 24853077 DOI: 10.1002/Bit.25262  0.613
2014 Miller W, Schlinker A, Radwanski K, Wegener C, Min KA. Producing and harvesting culture-derived platelets with functional activity from blood stem cells New Biotechnology. 31: S12. DOI: 10.1016/J.Nbt.2014.05.1638  0.784
2013 Kuo HY, Deluca TA, Miller WM, Mrksich M. Profiling deacetylase activities in cell lysates with peptide arrays and SAMDI mass spectrometry Analytical Chemistry. 85: 10635-10642. PMID 24088168 DOI: 10.1021/Ac402614X  0.358
2013 Ojima Y, Duncan MT, Nurhayati RW, Taya M, Miller WM. Synergistic effect of hydrogen peroxide on polyploidization during the megakaryocytic differentiation of K562 leukemia cells by PMA. Experimental Cell Research. 319: 2205-15. PMID 23770036 DOI: 10.1016/J.Yexcr.2013.06.002  0.413
2013 Konieczna IM, Panuganti S, DeLuca TA, Papoutsakis ET, Eklund EA, Miller WM. Administration of nicotinamide does not increase platelet levels in mice. Blood Cells, Molecules & Diseases. 50: 171-6. PMID 23265740 DOI: 10.1016/J.Bcmd.2012.11.007  0.356
2013 Panuganti S, Schlinker AC, Lindholm PF, Papoutsakis ET, Miller WM. Three-stage ex vivo expansion of high-ploidy megakaryocytic cells: toward large-scale platelet production. Tissue Engineering. Part A. 19: 998-1014. PMID 23190353 DOI: 10.1089/Ten.Tea.2011.0111  0.787
2013 Radwanski K, Wegener C, Miller WM, Min K. Separation Of In Vitro-Derived Megakaryocytes and Platelets Using Spinning Membrane Filtration Blood. 122: 3654-3654. DOI: 10.1182/Blood.V122.21.3654.3654  0.38
2013 Konieczna IM, He J, Mathew JM, Miller WM, Leventhal JR. 35-OR Human Immunology. 74: 27. DOI: 10.1016/J.Humimm.2013.08.046  0.359
2012 Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET. Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation. Physiological Genomics. 44: 638-50. PMID 22548738 DOI: 10.1152/Physiolgenomics.00028.2012  0.326
2012 McAdams TA, Sandstrom CE, Miller WM, Bender JG, Papoutsakis ET. Ex vivo expansion of primitive hematopoietic cells for cellular therapies: An overview. Cytotechnology. 18: 133-46. PMID 22358646 DOI: 10.1007/Bf00744329  0.444
2012 Grammatikos S, Harvey M, Subbaiah P, Victor T, Miller W. Loss of Fatty-Acid delta(6) desaturating ability in human mammary epithelial-cells that express an activated C-ha-ras oncogene. International Journal of Oncology. 6: 1039-46. PMID 21556637 DOI: 10.3892/Ijo.6.5.1039  0.419
2012 Collins PC, Nielsen LK, Wong CK, Papoutsakis ET, Miller WM. Real-time method for determining the colony-forming cell content of human hematopoietic cell cultures. Biotechnology and Bioengineering. 55: 693-700. PMID 18636579 DOI: 10.1002/(Sici)1097-0290(19970820)55:4<693::Aid-Bit11>3.0.Co;2-D  0.409
2012 Pasternak AS, Miller WM. Measurement of trans-epithelial electrical resistance in perfusion: potential application for in vitro ocular toxicity testing. Biotechnology and Bioengineering. 50: 568-79. PMID 18627020 DOI: 10.1002/(Sici)1097-0290(19960605)50:5<568::Aid-Bit12>3.0.Co;2-F  0.325
2010 Panuganti S, Papoutsakis ET, Miller WM. Bone marrow niche-inspired, multiphase expansion of megakaryocytic progenitors with high polyploidization potential. Cytotherapy. 12: 767-82. PMID 20482285 DOI: 10.3109/14653241003786148  0.39
2010 Lin AA, Kimura R, Miller WM. Production of tPA in recombinant CHO cells under oxygen-limited conditions. Biotechnology and Bioengineering. 42: 339-50. PMID 18613018 DOI: 10.1002/Bit.260420311  0.405
2010 Reddy S, Bauer KD, Miller WM. Determination of antibody content in live versus dead hybridoma cells: analysis of antibody production in osmotically stressed cultures. Biotechnology and Bioengineering. 40: 947-64. PMID 18601202 DOI: 10.1002/Bit.260400811  0.377
2009 Chen Y, Ott CJ, Townsend K, Subbaiah P, Aiyar A, Miller WM. Cholesterol Supplementation During Production Increases the Infectivity of Retroviral and Lentiviral Vectors Pseudotyped with the Vesicular Stomatitis Virus Glycoprotein (VSV-G). Biochemical Engineering Journal. 44: 199-207. PMID 20160854 DOI: 10.1016/J.Bej.2008.12.004  0.706
2009 Giammona LM, Panuganti S, Kemper JM, Apostolidis PA, Lindsey S, Papoutsakis ET, Miller WM. Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition. Experimental Hematology. 37: 1340-1352.e3. PMID 19715739 DOI: 10.1016/J.Exphem.2009.08.004  0.424
2009 Garcia AS, Dellatore SM, Messersmith PB, Miller WM. Effects of supported lipid monolayer fluidity on the adhesion of hematopoietic progenitor cell lines to fibronectin-derived peptide ligands for alpha5beta1 and alpha4beta1 integrins. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 2994-3002. PMID 19437769 DOI: 10.1021/La802772Y  0.795
2009 Sandstrom CE, Miller WM, Papoutsakis ET. Serum-free media for cultures of primitive and mature hematopoietic cells. Biotechnology and Bioengineering. 43: 706-33. PMID 18615795 DOI: 10.1002/Bit.260430806  0.415
2009 Lin AA, Miller WM. CHO cell responses to low oxygen: regulation of oxygen consumption and sensitization to oxidative stress. Biotechnology and Bioengineering. 40: 505-16. PMID 18601145 DOI: 10.1002/Bit.260400409  0.345
2008 Dellatore SM, Garcia AS, Miller WM. Mimicking stem cell niches to increase stem cell expansion. Current Opinion in Biotechnology. 19: 534-40. PMID 18725291 DOI: 10.1016/J.Copbio.2008.07.010  0.799
2008 Fuhrken PG, Apostolidis PA, Lindsey S, Miller WM, Papoutsakis ET. Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis. The Journal of Biological Chemistry. 283: 15589-600. PMID 18397889 DOI: 10.1074/Jbc.M801923200  0.376
2008 Fuhrken PG, Chen C, Apostolidis PA, Wang M, Miller WM, Papoutsakis ET. Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis. Physiological Genomics. 33: 159-69. PMID 18252802 DOI: 10.1152/Physiolgenomics.00127.2007  0.303
2008 Panuganti S, Papoutsakis ET, Miller WM. Nicotinamide increases the megakaryocytic maturation of human hematopoietic stem cells primarily due to sirtuin inhibition Aiche Annual Meeting, Conference Proceedings. DOI: 10.1182/Blood.V112.11.2445.2445  0.421
2007 Lee H, Dellatore SM, Miller WM, Messersmith PB. Mussel-inspired surface chemistry for multifunctional coatings. Science (New York, N.Y.). 318: 426-30. PMID 17947576 DOI: 10.1126/Science.1147241  0.738
2007 Gunawan RC, King JA, Lee BP, Messersmith PB, Miller WM. Surface presentation of bioactive ligands in a nonadhesive background using DOPA-tethered biotinylated poly(ethylene glycol). Langmuir : the Acs Journal of Surfaces and Colloids. 23: 10635-43. PMID 17803326 DOI: 10.1021/La701415Z  0.307
2007 King JA, Miller WM. Bioreactor development for stem cell expansion and controlled differentiation. Current Opinion in Chemical Biology. 11: 394-8. PMID 17656148 DOI: 10.1016/J.Cbpa.2007.05.034  0.41
2007 Huang LT, Paredes CJ, Papoutsakis ET, Miller WM. Gene expression analysis illuminates the transcriptional programs underlying the functional activity of ex vivo-expanded granulocytes. Physiological Genomics. 31: 114-25. PMID 17550995 DOI: 10.1152/Physiolgenomics.00053.2007  0.306
2007 Pascoe DE, Arnott D, Papoutsakis ET, Miller WM, Andersen DC. Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles. Biotechnology and Bioengineering. 98: 391-410. PMID 17461427 DOI: 10.1002/Bit.21460  0.403
2007 Fuhrken PG, Chen C, Miller WM, Papoutsakis ET. Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation. Experimental Hematology. 35: 476-489. PMID 17309828 DOI: 10.1016/J.Exphem.2006.10.017  0.347
2006 Giammona LM, Fuhrken PG, Papoutsakis ET, Miller WM. Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes. British Journal of Haematology. 135: 554-66. PMID 17054670 DOI: 10.1111/J.1365-2141.2006.06341.X  0.438
2005 Chen Y, Miller WM, Aiyar A. Transduction efficiency of pantropic retroviral vectors is controlled by the envelope plasmid to vector plasmid ratio. Biotechnology Progress. 21: 274-82. PMID 15903266 DOI: 10.1021/Bp049865X  0.732
2005 Abston LR, Miller WM. Effects of NHE1 expression level on CHO cell responses to environmental stress. Biotechnology Progress. 21: 562-7. PMID 15801799 DOI: 10.1021/Bp049680Q  0.779
2005 Miller WM, Huang LT, Chen C, Papoutsakis ET. Developmental Plasticity Revealed by Lineage Switch from Committed Megakaryocytic Cells to Granulocytic Cells. Blood. 106: 3610-3610. DOI: 10.1182/Blood.V106.11.3610.3610  0.393
2005 Dellatore SM, King JA, Jensen TW, Hu B, Messersmith PB, Miller WM. Immobilized Thrombopoietin (TPO) Lipopeptide Mimic Supports Similar Signaling and CD34+ Cell Differentiation as Soluble TPO. Blood. 106: 3150-3150. DOI: 10.1182/Blood.V106.11.3150.3150  0.796
2005 Giammona LM, Papoutsakis E, Miller WM. Nicotinamide Enhances the Polyploidization of Primary Megakaryocytes. Blood. 106: 1366-1366. DOI: 10.1182/Blood.V106.11.1366.1366  0.484
2004 Jensen TW, Hu BH, Delatore SM, Garcia AS, Messersmith PB, Miller WM. Lipopeptides incorporated into supported phospholipid monolayers have high specific activity at low incorporation levels. Journal of the American Chemical Society. 126: 15223-30. PMID 15548019 DOI: 10.1021/Ja048684O  0.354
2004 Walker EB, Haley D, Miller W, Floyd K, Wisner KP, Sanjuan N, Maecker H, Romero P, Hu HM, Alvord WG, Smith JW, Fox BA, Urba WJ. gp100(209-2M) peptide immunization of human lymphocyte antigen-A2+ stage I-III melanoma patients induces significant increase in antigen-specific effector and long-term memory CD8+ T cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 668-80. PMID 14760090 DOI: 10.1158/1078-0432.Ccr-0095-03  0.324
2004 Townsend K, Chen Y, Dayao J, Farson D, Miller WM, Lin A. 82. Adaptation of a lentiviral vector producer cell line to reduced-serum, suspension culture for large scale production Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.017  0.411
2003 Jensen TW, Chen Y, Miller WM. Small increases in pH enhance retroviral vector transduction efficiency of NIH-3T3 cells. Biotechnology Progress. 19: 216-23. PMID 12573028 DOI: 10.1021/Bp025604G  0.35
2002 Chapman KE, Waters CM, Miller WM. Continuous exposure of airway epithelial cells to hydrogen peroxide: Protection by KGF Journal of Cellular Physiology. 192: 71-80. PMID 12115738 DOI: 10.1002/Jcp.10115  0.344
2002 Yang H, Miller WM, Papoutsakis ET. Higher pH promotes megakaryocytic maturation and apoptosis Stem Cells. 20: 320-328. PMID 12110701 DOI: 10.1634/Stemcells.20-4-320  0.446
2002 deZengotita VM, Abston LR, Schmelzer AE, Shaw S, Miller WM. Selected amino acids protect hybridoma and CHO cells from elevated carbon dioxide and osmolality. Biotechnology and Bioengineering. 78: 741-52. PMID 12001166 DOI: 10.1002/Bit.10255  0.756
2002 Schmelzer AE, Miller WM. Hyperosmotic stress and elevated pCO2 alter monoclonal antibody charge distribution and monosaccharide content. Biotechnology Progress. 18: 346-53. PMID 11934306 DOI: 10.1021/Bp010187D  0.768
2002 Hevehan DL, Miller WM, Papoutsakis ET. Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation. Blood. 99: 1627-37. PMID 11861277 DOI: 10.1182/Blood.V99.5.1627  0.312
2002 deZengotita VM, Schmelzer AE, Miller WM. Characterization of hybridoma cell responses to elevated pCO(2) and osmolality: intracellular pH, cell size, apoptosis, and metabolism. Biotechnology and Bioengineering. 77: 369-80. PMID 11787010 DOI: 10.1002/Bit.10176  0.807
2002 Schmelzer AE, Miller WM. Effects of osmoprotectant compounds on NCAM polysialylation under hyperosmotic stress and elevated pCO(2). Biotechnology and Bioengineering. 77: 359-68. PMID 11787009 DOI: 10.1002/Bit.10175  0.789
2001 Chow DC, Wenning LA, Miller WM, Papoutsakis ET. Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models. Biophysical Journal. 81: 685-96. PMID 11463617 DOI: 10.1016/S0006-3495(01)75733-5  0.344
2001 Chow DC, Wenning LA, Miller WM, Papoutsakis ET. Modeling pO(2) distributions in the bone marrow hematopoietic compartment. I. Krogh's model. Biophysical Journal. 81: 675-84. PMID 11463616 DOI: 10.1016/S0006-3495(01)75732-3  0.353
2001 Yang H, Papoutsakis ET, Miller WM. Model-based estimation of myeloid hematopoietic progenitor cells in ex vivo cultures for cell and gene therapies Biotechnology and Bioengineering. 72: 144-155. PMID 11114652 DOI: 10.1002/1097-0290(20000120)72:2<144::Aid-Bit3>3.0.Co;2-4  0.475
2000 Sandstrom CE, Bender JG, Miller WM, Papoutsakis ET. Development of novel perfusion chamber to retain nonadherent cells and its use for comparison of human “mobilized” peripheral blood mononuclear cell cultures with and without irradiated bone marrow stroma Biotechnology and Bioengineering. 50: 493-504. PMID 18627011 DOI: 10.1002/(Sici)1097-0290(19960605)50:5<493::Aid-Bit3>3.0.Co;2-A  0.414
2000 Patel SD, Guo R, Miller WM, Papoutsakis ET, Minster NI, Baum CM, Winter JN. Clinical-scale production of granulocyte progenitor and post-progenitor cells using daniplestim, leridistim, Progenipoietin, Promegapoietin and autologous plasma. Cytotherapy. 2: 85-94. PMID 12042045 DOI: 10.1080/146532400539080  0.332
2000 Patel SD, Miller WM, Winter JN, Papoutsakis ET. Cell density-dependent proliferation in frequently-fed peripheral blood mononuclear cell cultures Cytotherapy. 2: 267-280. PMID 12042036 DOI: 10.1080/146532400539206  0.464
2000 Patel SD, Papoutsakis ET, Winter JN, Miller WM. The lactate issue revisited: novel feeding protocols to examine inhibition of cell proliferation and glucose metabolism in hematopoietic cell cultures. Biotechnology Progress. 16: 885-92. PMID 11027185 DOI: 10.1021/Bp000080A  0.476
2000 Hevehan DL, Wenning LA, Miller WM, Papoutsakis ET. Dynamic model of ex vivo granulocytic kinetics to examine the effects of oxygen tension, pH, and interleukin-3. Experimental Hematology. 28: 1016-28. PMID 11008014 DOI: 10.1016/S0301-472X(00)00505-1  0.415
2000 deZengotita VM, Miller WM, Aunins JG, Zhou W. Phosphate feeding improves high-cell-concentration NS0 myeloma culture performance for monoclonal antibody production. Biotechnology and Bioengineering. 69: 566-76. PMID 10898866 DOI: 10.1002/1097-0290(20000905)69:5<566::Aid-Bit11>3.0.Co;2-4  0.459
2000 Hevehan DL, Papoutsakis ET, Miller WM. Physiologically significant effects of pH and oxygen tension on granulopoiesis Experimental Hematology. 28: 267-275. PMID 10720691 DOI: 10.1016/S0301-472X(99)00150-2  0.405
2000 Miller WM, Blanch HW, Wilke CR. A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH. Reprinted from Biotechnology and Bioengineering, Vol. 32, Pp 947-965 (1988). Biotechnology and Bioengineering. 67: 853-71. PMID 10699863 DOI: 10.1002/(SICI)1097-0290(20000320)67:6<853::AID-BIT20>3.0.CO;2-4  0.706
2000 Schmelzer AE, deZengotita VM, Miller WM. Considerations for osmolality measurement under elevated pCO(2): comparison of vapor pressure and freezing point osmometry. Biotechnology and Bioengineering. 67: 189-96. PMID 10592516 DOI: 10.1002/(Sici)1097-0290(20000120)67:2<189::Aid-Bit8>3.0.Co;2-U  0.762
2000 Mostafa SS, Miller WM, Papoutsakis ET. Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes British Journal of Haematology. 111: 879-889. DOI: 10.1111/J.1365-2141.2000.02457.X  0.353
2000 Hevehan DL, Wenning LA, Papoutsakis E, Miller WM. A dynamic model of ex vivo granulopoiesis Experimental Hematology. 28: 1498. DOI: 10.1016/S0301-472X(00)00661-5  0.416
2000 Mostafa S, Papoutsakis E, Miller W. Oxygen tension has significant effects on human megakaryocyte maturation Experimental Hematology. 28: 1498. DOI: 10.1016/S0301-472X(00)00631-7  0.341
1999 Collins PC, Patel SD, Miller WM, Papoutsakis ET. Initiation, maintenance, and quantification of human hematopoietic cell cultures. Methods in Molecular Medicine. 18: 271-92. PMID 21370184 DOI: 10.1385/0-89603-516-6:271  0.444
1999 Collins PC, Patel SD, Papoutsakis ET, Miller WM. Nuclei-size distributions as predictive tools of hematopoietic cell proliferation Cytotherapy. 1: 99-110. PMID 19746586 DOI: 10.1080/0032472031000141247  0.457
1999 Guo M, Miller WM, Papoutsakis ET, Patel S, James C, Goolsby C, Winter JN. Ex-vivo expansion of CFU-GM and BFU-E in unselected PBMC cultures with Flt3L is enhanced by autologous plasma. Cytotherapy. 1: 183-94. PMID 12881174 DOI: 10.1080/14653249910001591266  0.364
1999 Zanghi JA, Schmelzer AE, Mendoza TP, Knop RH, Miller WM. Bicarbonate concentration and osmolality are key determinants in the inhibition of CHO cell polysialylation under elevated pCO(2) or pH. Biotechnology and Bioengineering. 65: 182-91. PMID 10458739 DOI: 10.1002/(Sici)1097-0290(19991020)65:2<182::Aid-Bit8>3.0.Co;2-D  0.79
1999 Zanghi JA, Mendoza TP, Schmelzer AE, Knop RH, Miller WM. Role of nucleotide sugar pools in the inhibition of NCAM polysialylation by ammonia. Biotechnology Progress. 14: 834-44. PMID 9841644 DOI: 10.1021/Bp9800945  0.796
1999 Kimura R, Miller WM. Erratum: Effects of elevated pCO2 and/or osmolality on the growth and recombinant tPA production of CHO cells (Biotechnology and Bioengineering 52 (152-160)) Biotechnology and Bioengineering. 63. DOI: 10.1002/(Sici)1097-0290(19990420)63:2<253::Aid-Bit15>3.0.Co;2-D  0.403
1998 Dezengotita VM, Kimura R, Miller WM. Effects of CO2 and osmolality on hybridoma cells: growth, metabolism and monoclonal antibody production. Cytotechnology. 28: 213-27. PMID 19003422 DOI: 10.1023/A:1008010605287  0.465
1998 Collins PC, Miller WM, Papoutsakis ET. Stirred culture of peripheral and cord blood hematopoietic cells offers advantages over traditional static systems for clinically relevant applications Biotechnology and Bioengineering. 59: 534-543. PMID 10099369 DOI: 10.1002/(Sici)1097-0290(19980905)59:5<534::Aid-Bit2>3.0.Co;2-B  0.42
1998 Mcadams TA, Miller WM, Papoutsakis ET. pH is a potent modulator of erythroid differentiation British Journal of Haematology. 103: 317-325. PMID 9827900 DOI: 10.1046/J.1365-2141.1998.00975.X  0.416
1998 Zanghi JA, Mendoza TP, Knop RH, Miller WM. Ammonia inhibits neural cell adhesion molecule polysialylation in Chinese hamster ovary and small cell lung cancer cells. Journal of Cellular Physiology. 177: 248-63. PMID 9766522 DOI: 10.1002/(Sici)1097-4652(199811)177:2<248::Aid-Jcp7>3.0.Co;2-N  0.459
1998 Horner M, Miller WM, Ottino JM, Papoutsakis ET. Transport in a grooved perfusion flat-bed bioreactor for cell therapy applications. Biotechnology Progress. 14: 689-98. PMID 9758657 DOI: 10.1021/Bp980067E  0.402
1998 Collins PC, Nielsen LK, Patel SD, Papoutsakis ET, Miller WM. Characterization of hematopoietic cell expansion, oxygen uptake, and glycolysis in a controlled, stirred-tank bioreactor system. Biotechnology Progress. 14: 466-72. PMID 9622528 DOI: 10.1021/Bp980032E  0.477
1997 Laluppa JA, McAdams TA, Papoutsakis ET, Miller WM. Culture materials affect ex vivo expansion of hematopoietic progenitor cells Journal of Biomedical Materials Research. 36: 347-359. PMID 9260106 DOI: 10.1002/(Sici)1097-4636(19970905)36:3<347::Aid-Jbm10>3.0.Co;2-B  0.425
1997 Mcadams TA, Miller WM, Papoutsakis ET. Variations in culture pH affect the cloning efficiency and differentiation of progenitor cells in ex vivo haemopoiesis British Journal of Haematology. 97: 889-895. PMID 9217193 DOI: 10.1046/J.1365-2141.1997.1372951.X  0.432
1997 Kimura R, Miller WM. Glycosylation of CHO-derived recombinant tPA produced under elevated pCO2. Biotechnology Progress. 13: 311-7. PMID 9190082 DOI: 10.1021/Bp9700162  0.483
1997 Laiuppa JA, Papoutsakis ET, Miller WM. Evaluation of cytokines for expansion of the megakaryocyte and granulocyte lineages Stem Cells. 15: 198-206. PMID 9170211 DOI: 10.1002/Stem.150198  0.364
1997 LaIuppa JA, Papoutsakis ET, Miller WM. Ex vivo expansion of hematopoietic stem and progenitor cells for transplantation Cancer Treatment and Research. 77: 159-186. PMID 9071503 DOI: 10.1007/978-1-4615-6349-5_8  0.414
1997 Sandstrom CE, Collins PC, McAdams TA, Bender JG, Papoutsakis ET, Miller WM. Comparison of whole serum-deprived media for ex vivo expansion of hematopoietic progenitor cells from cord blood and mobilized peripheral blood mononuclear cells. Journal of Hematotherapy. 5: 461-73. PMID 8938518 DOI: 10.1089/Scd.1.1996.5.461  0.449
1996 Kimura R, Miller WM. Effects of elevated pCO(2) and/or osmolality on the growth and recombinant tPA production of CHO cells. Biotechnology and Bioengineering. 52: 152-60. PMID 18629861 DOI: 10.1002/(Sici)1097-0290(19961005)52:1<152::Aid-Bit15>3.0.Co;2-Q  0.442
1996 McAdams TA, Winter JN, Miller WM, Papoutsakis ET. Hematopoietic cell culture therapies (Part II): Clinical aspects and applications Trends in Biotechnology. 14: 388-396. PMID 8987637 DOI: 10.1016/0167-7799(96)10054-8  0.425
1996 McAdams TA, Miller WM, Papoutsakis ET. Hematopoietic cell culture therapies (Part I): Cell culture considerations Trends in Biotechnology. 14: 341-349. PMID 8818288 DOI: 10.1016/0167-7799(96)10047-0  0.467
1996 Collins PC, Papoutsakis ET, Miller WM. Ex vivo culture systems for hematopoietic cells Current Opinion in Biotechnology. 7: 223-230. PMID 8791333 DOI: 10.1016/S0958-1669(96)80017-6  0.366
1995 Grammatikos SI, Subbaiah PV, Victor TA, Miller WM. Diversity in the ability of cultured cells to elongate and desaturate essential (n-6 and n-3) fatty acids. Annals of the New York Academy of Sciences. 745: 92-105. PMID 7832535 DOI: 10.1111/J.1749-6632.1994.Tb44366.X  0.424
1995 Grammatikos SI, Subbaiah PV, Victor TA, Miller WM. Diverse effects of essential (n-6 and n-3) fatty acids on cultured cells. Cytotechnology. 15: 31-50. PMID 7765945 DOI: 10.1007/Bf00762377  0.435
1995 Pasternak AS, Miller WM. First-order toxicity assays for eye irritation using cell lines: parameters that affect in vitro evaluation. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 25: 253-63. PMID 7665009 DOI: 10.1006/Faat.1995.1061  0.324
1995 Sandstrom C, Bender J, Papoutsakis E, Miller W. Effects of CD34+ cell selection and perfusion on ex vivo expansion of peripheral blood mononuclear cells Blood. 86: 958-970. DOI: 10.1182/Blood.V86.3.958.Bloodjournal863958  0.417
1994 Pederson NV, Zanghi JA, Miller WM, Knop RH. Discrimination of fluorinated uridine metabolites in N‐417 small cell lung cancer cell extracts via 19F‐ and 31P‐NMR Magnetic Resonance in Medicine. 31: 224-228. PMID 8133759 DOI: 10.1002/Mrm.1910310217  0.314
1994 Grammatikos SI, Subbaiah PV, Victor TA, Miller WM. n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines. British Journal of Cancer. 70: 219-27. PMID 8054269 DOI: 10.1038/Bjc.1994.283  0.376
1994 Reddy S, Miller WM. Effects of abrupt and gradual osmotic stress on antibody production and content in hybridoma cells that differ in production kinetics. Biotechnology Progress. 10: 165-73. PMID 7764674 DOI: 10.1021/Bp00026A006  0.376
1993 Koller MR, Bender JG, Miller WM, Papoutsakis ET. Expansion of primitive human hematopoietic progenitors in a perfusion bioreactor system with IL-3, IL-6, and stem cell factor Nature Biotechnology. 11: 358-363. DOI: 10.1038/Nbt0393-358  0.35
1992 Lin AA, Miller WM. Modulation of glutathione level in CHO cells. Effects of oxygen concentration and prior exposure to hypoxia. Annals of the New York Academy of Sciences. 665: 117-26. PMID 1416597 DOI: 10.1111/J.1749-6632.1992.Tb42579.X  0.378
1992 Koller MR, Bender JG, Papoutsakis ET, Miller WM. Beneficial effects of reduced oxygen tension and perfusion in long-term hematopoietic cultures Annals of the New York Academy of Sciences. 665: 105-116. PMID 1416596 DOI: 10.1111/J.1749-6632.1992.Tb42578.X  0.439
1992 Reddy S, Miller WM. Hybridoma antibody content and production rate in continuous culture: Effect of dilution rate Biotechnology Letters. 14: 1007-1012. DOI: 10.1007/Bf01021049  0.309
1991 Miller WM, Blanch HW. Regulation of animal cell metabolism in bioreactors. Biotechnology (Reading, Mass.). 17: 119-61. PMID 2049537 DOI: 10.1016/B978-0-409-90123-8.50012-4  0.54
1991 Lin AA, Nguyen T, Miller WM. A rapid method for counting cell nuclei using a particle sizer/counter Biotechnology Techniques. 5: 153-156. DOI: 10.1007/Bf00159989  0.31
1989 Miller WM, Wilke CR, Blanch HW. The transient responses of hybridoma cells to nutrient additions in continuous culture: II. Glutamine pulse and step changes. Biotechnology and Bioengineering. 33: 487-99. PMID 18587940 DOI: 10.1002/bit.260330414  0.68
1989 Miller WM, Wilke CR, Blanch HW. Transient responses of hybridoma cells to nutrient additions in continuous culture: I. Glucose pulse and step changes. Biotechnology and Bioengineering. 33: 477-86. PMID 18587939 DOI: 10.1002/Bit.260330413  0.709
1988 Miller WM, Blanch HW, Wilke CR. A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH. Biotechnology and Bioengineering. 32: 947-65. PMID 18587813 DOI: 10.1002/Bit.260320803  0.725
1988 Miller WM, Wilke CR, Blanch HW. Transient responses of hybridoma cells to lactate and ammonia pulse and step changes in continuous culture Bioprocess Engineering. 3: 113-122. DOI: 10.1007/Bf00373474  0.737
1988 Miller WM, Wilke CR, Blanch HW. Transient responses of hybridoma metabolism to changes in the oxygen supply rate in continuous culture Bioprocess Engineering. 3: 103-111. DOI: 10.1007/Bf00373473  0.713
1987 Miller WM, Wilke CR, Blanch HW. Effects of dissolved oxygen concentration on hybridoma growth and metabolism in continuous culture. Journal of Cellular Physiology. 132: 524-30. PMID 3654764 DOI: 10.1002/Jcp.1041320315  0.725
1986 Miller WM, Lin AA, Wilke CR, Blanch HW. Polymer biocompatibility?effect on hybridoma growth and metabolism Biotechnology Letters. 8: 463-468. DOI: 10.1007/Bf01025202  0.704
1985 Trevisan M, Cooper R, Ostrow D, Sempos C, Sparks S, Nanas S, Miller W, Stamler J. Red cell cation transport: differences between black and white school children. Journal of Hypertension. 1: 245-9. PMID 6681042 DOI: 10.1097/00004872-198310000-00008  0.313
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