Gonçalo Bernardes - Publications

Affiliations: 
2013- University of Cambridge, Cambridge, England, United Kingdom 
Area:
Chemical biology
Website:
https://gbernardeslab.com/

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dal Forno GM, Latocheski E, Beatriz Machado A, Becher J, Dunsmore L, St John AL, Oliveira BL, Navo CD, Jiménez-Osés G, Fior R, Domingos JB, Bernardes GJL. Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C-C Bond Cleavage Reactions. Journal of the American Chemical Society. PMID 37133984 DOI: 10.1021/jacs.3c01960  0.74
2023 Nadendla K, Simpson GG, Becher J, Journeaux T, Cabeza-Cabrerizo M, Bernardes GJL. Strategies for Conditional Regulation of Proteins. Jacs Au. 3: 344-357. PMID 36873677 DOI: 10.1021/jacsau.2c00654  0.763
2022 Taylor RJ, Geeson MB, Journeaux T, Bernardes GJL. Chemical and Enzymatic Methods for Post-Translational Protein-Protein Conjugation. Journal of the American Chemical Society. PMID 35912579 DOI: 10.1021/jacs.2c00129  0.345
2022 Taylor RJ, Aguilar Rangel M, Geeson MB, Sormanni P, Vendruscolo M, Bernardes GJL. π-Clamp-Mediated Homo- and Heterodimerization of Single-Domain Antibodies via Site-Specific Homobifunctional Conjugation. Journal of the American Chemical Society. 144: 13026-13031. PMID 35834748 DOI: 10.1021/jacs.2c04747  0.33
2022 Istrate A, Geeson MB, Navo CD, Sousa BB, Marques MC, Taylor RJ, Journeaux T, Oehler SR, Mortensen MR, Deery MJ, Bond AD, Corzana F, Jiménez-Osés G, Bernardes GJL. Platform for Orthogonal -Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents. Journal of the American Chemical Society. PMID 35658467 DOI: 10.1021/jacs.2c02185  0.358
2021 Konč J, Sabatino V, Jiménez-Moreno E, Latocheski E, Pérez LR, Day J, Domingos JB, Bernardes GJL. Controlled In-Cell Generation of Active Palladium(0) Species for Bioorthogonal Decaging. Angewandte Chemie (International Ed. in English). PMID 34739737 DOI: 10.1002/anie.202113519  0.729
2021 Hakala TA, Yates EV, Challa PK, Toprakcioglu Z, Nadendla K, Matak-Vinkovic D, Dobson CM, Martínez R, Corzana F, Knowles TPJ, Bernardes GJL. Accelerating Reaction Rates of Biomolecules by Using Shear Stress in Artificial Capillary Systems. Journal of the American Chemical Society. PMID 34606279 DOI: 10.1021/jacs.1c03681  0.748
2021 Laserna V, Abegg D, Afonso C, Martin E, Adibekian A, Ravn P, Corzana F, Bernardes GJL. Dichloro Butendiamides as Irreversible Site-Selective Protein Conjugation Reagent. Angewandte Chemie (International Ed. in English). PMID 34472678 DOI: 10.1002/anie.202108791  0.39
2021 Laserna V, Istrate A, Kafuta K, Hakala TA, Knowles TPJ, Alcarazo M, Bernardes GJL. Protein Conjugation by Electrophilic Alkynylation Using 5-(Alkynyl)dibenzothiophenium Triflates. Bioconjugate Chemistry. PMID 34232618 DOI: 10.1021/acs.bioconjchem.1c00317  0.412
2020 Latocheski E, Dal Forno GM, Ferreira TM, Oliveira BL, Bernardes GJL, Domingos JB. Mechanistic insights into transition metal-mediated bioorthogonal uncaging reactions. Chemical Society Reviews. PMID 33026001 DOI: 10.1039/d0cs00630k  0.752
2020 Matos MJ, Brown L, Bernardim B, Guerreiro A, Jiménez-Osés G, Bernardes GJL. Sequential dual site-selective protein labelling enabled by lysine modification. Bioorganic & Medicinal Chemistry. 28: 115783. PMID 33007561 DOI: 10.1016/j.bmc.2020.115783  0.345
2020 Vantourout JC, Adusumalli SR, Knouse KW, Flood DT, Ramirez A, Padial NM, Istrate A, Maziarz K, deGruyter JN, Merchant RR, Qiao JX, Schmidt MA, Deery MJ, Eastgate MD, Dawson PE, ... Bernardes GJL, et al. Serine-Selective Bioconjugation. Journal of the American Chemical Society. PMID 32965106 DOI: 10.1021/jacs.0c05595  0.75
2020 Oliveira BL, Stenton BJ, V B U, de Almeida CR, Conde J, Negrão M, Schneider FSS, Cordeiro C, Godinho Ferreira M, Caramori GF, Domingos JB, Fior R, Bernardes GJL. Platinum-triggered Bond-cleavage of Pentynoyl amide and N-propargyl handles for Drug-Activation. Journal of the American Chemical Society. PMID 32456416 DOI: 10.1021/Jacs.0C01622  0.659
2020 McAulay K, Hoyt EA, Thomas M, Schimpl M, Bodnarchuk MS, Lewis HJ, Barratt D, Bhavsar D, Robinson DM, Deery MJ, Ogg D, Bernardes GJL, Ward RA, Waring MJ, Kettle JG. Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors. Journal of the American Chemical Society. PMID 32412754 DOI: 10.1021/Jacs.9B13391  0.305
2020 Bernardim B, Dunsmore L, Li H, Hocking B, Nuñez-Franco R, Navo CD, Jiménez-Osés G, Burtoloso ACB, Bernardes GJL. Precise installation of diazo-tagged side-chains on proteins to enable in vitro and in-cell site-specific labelling. Bioconjugate Chemistry. PMID 32375474 DOI: 10.1021/Acs.Bioconjchem.0C00232  0.352
2020 Gil de Montes E, Istrate A, Navo C, Jiménez-Moreno E, Hoyt E, Corzana F, Robina I, Jiménez-Osés G, Moreno-Vargas A, Bernardes GJL. Stable pyrrole-linked bioconjugates through tetrazine-triggered azanorbornadiene fragmentation. Angewandte Chemie (International Ed. in English). PMID 31981460 DOI: 10.1002/Anie.201914529  0.397
2019 Matos MJ, Jiménez-Osés G, Bernardes GJL. Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent. Methods in Molecular Biology (Clifton, N.J.). 2033: 25-37. PMID 31332745 DOI: 10.1007/978-1-4939-9654-4_3  0.343
2019 Gil de Montes E, Jiménez-Moreno E, Oliveira BL, Navo CD, Cal PMSD, Jiménez-Osés G, Robina I, Moreno-Vargas AJ, Bernardes GJL. Azabicyclic vinyl sulfones for residue-specific dual protein labelling. Chemical Science. 10: 4515-4522. PMID 31057781 DOI: 10.1039/C9Sc00125E  0.389
2019 Adusumalli SR, Bernardes GJL. Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation Chem. 5: 1932-1934. DOI: 10.1016/J.Chempr.2019.07.014  0.769
2018 Davies S, Stenton BJ, Bernardes GJL. Bioorthogonal Decaging Reactions for Targeted Drug Activation. Chimia. 72: 771-776. PMID 30514419 DOI: 10.2533/chimia.2018.771  0.311
2018 Bertoldo J, Terenzi H, Hüttelmaier S, Bernardes GJL. Posttranslational chemical mutagenesis: to reveal the role of non-catalytic cysteine residues in pathogenic bacterial phosphatases. Biochemistry. PMID 30280890 DOI: 10.1021/acs.biochem.8b00639  0.324
2018 Lee B, Sun S, Jiménez-Moreno E, Neves AA, Bernardes GJL. Site-selective installation of an electrophilic handle on proteins for bioconjugation. Bioorganic & Medicinal Chemistry. PMID 29482952 DOI: 10.1016/j.bmc.2018.02.028  0.393
2018 Matos M, Oliveira B, Martínez-Sáez N, Guerreiro A, Cal PMSD, Bertoldo J, Maneiro M, Perkins E, Howard J, Deery M, Chalker JM, Corzana F, Jiménez-Osés G, Bernardes GJL. Chemo and regioselective lysine modification on native proteins. Journal of the American Chemical Society. PMID 29473744 DOI: 10.1021/Jacs.7B12874  0.383
2017 Freedy AM, Matos MJ, Boutureira O, Corzana F, Guerreiro A, Akkapeddi P, Somovilla VJ, Rodrigues T, Nicholls K, Xie B, Jiménez-Osés G, Brindle KM, Neves AA, Bernardes GJL. Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation. Journal of the American Chemical Society. 139: 18365-18375. PMID 29206031 DOI: 10.1021/Jacs.7B10702  0.398
2017 Dadová J, Wu KJ, Isenegger PG, Errey JC, Bernardes GJL, Chalker JM, Raich L, Rovira C, Davis BG. Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites. Acs Central Science. 3: 1168-1173. PMID 29202018 DOI: 10.1021/Acscentsci.7B00341  0.725
2017 Kwan TT, Boutureira O, Frye EC, Walsh SJ, Gupta MK, Wallace S, Wu Y, Zhang F, Sore HF, Galloway WRJD, Chin JW, Welch M, Bernardes GJL, Spring DR. Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst. Chemical Science. 8: 3871-3878. PMID 28966779 DOI: 10.1039/C6Sc05313K  0.321
2017 Kitowski A, Jiménez-Moreno E, Salvadó M, Mestre J, Castillón S, Jiménez-Osés G, Boutureira O, Bernardes GJL. Oxidative Activation of C-S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides. Organic Letters. PMID 28956446 DOI: 10.1021/Acs.Orglett.7B02886  0.311
2017 Kim WG, Kang ME, Lee JB, Jeon MH, Lee S, Lee J, Choi B, Cal PMSD, Kang S, Kee JM, Bernardes GJL, Rohde JU, Choe W, Hong SY. Nickel-Catalyzed Azide-Alkyne Cycloaddition to Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water. Journal of the American Chemical Society. PMID 28814075 DOI: 10.1021/Jacs.7B06338  0.499
2017 Boutureira O, Martínez-Sáez N, Brindle KM, Neves AA, Corzana F, Bernardes GJ. Site-Selective Modification of Proteins with Oxetanes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28261889 DOI: 10.1002/Chem.201700745  0.363
2016 Jiménez-Moreno E, Guo Z, Oliveira BL, Albuquerque IS, Kitowski A, Guerreiro A, Boutureira O, Rodrigues T, Jiménez-Osés G, Bernardes GJ. Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells. Angewandte Chemie (International Ed. in English). PMID 27930843 DOI: 10.1002/anie.201609607  0.306
2016 Bernardim B, Cal PM, Matos MJ, Oliveira BL, Martínez-Sáez N, Albuquerque IS, Perkins E, Corzana F, Burtoloso AC, Jiménez-Osés G, Bernardes GJ. Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents. Nature Communications. 7: 13128. PMID 27782215 DOI: 10.1038/Ncomms13128  0.38
2016 Oliveira BL, Guo Z, Boutureira O, Guerreiro A, Jiménez-Osés G, Bernardes GJ. A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells. Angewandte Chemie (International Ed. in English). PMID 27763724 DOI: 10.1002/anie.201608438  0.307
2016 Wright TH, Bower BJ, Chalker JM, Bernardes GJ, Wiewiora R, Ng WL, Raj R, Faulkner S, Vallée MR, Phanumartwiwath A, Coleman OD, Thézénas ML, Khan M, Galan SR, Lercher L, et al. Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity. Science (New York, N.Y.). PMID 27708059 DOI: 10.1126/Science.Aag1465  0.774
2016 Krall N, da Cruz FP, Boutureira O, Bernardes GJ. Site-selective protein-modification chemistry for basic biology and drug development. Nature Chemistry. 8: 103-13. PMID 26791892 DOI: 10.1038/nchem.2393  0.381
2014 Cal PM, Bernardes GJ, Gois PM. Cysteine-selective reactions for antibody conjugation. Angewandte Chemie (International Ed. in English). 53: 10585-7. PMID 25070879 DOI: 10.1002/anie.201405702  0.332
2014 Liu F, Vijayakrishnan B, Faridmoayer A, Taylor TA, Parsons TB, Bernardes GJ, Kowarik M, Davis BG. Rationally designed short polyisoprenol-linked PglB substrates for engineered polypeptide and protein N-glycosylation. Journal of the American Chemical Society. 136: 566-9. PMID 24377322 DOI: 10.1021/Ja409409H  0.507
2012 Boutureira O, Bernardes GJ, Fernández-González M, Anthony DC, Davis BG. Selenenylsulfide-linked homogeneous glycopeptides and glycoproteins: synthesis of human "hepatic Se metabolite A". Angewandte Chemie (International Ed. in English). 51: 1432-6. PMID 22213253 DOI: 10.1002/Anie.201106658  0.411
2011 Boutureira O, Bernardes GJ, D'Hooge F, Davis BG. Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars. Chemical Communications (Cambridge, England). 47: 10010-2. PMID 21833430 DOI: 10.1039/C1Cc13524D  0.428
2011 Bernardes GJ, Linderoth L, Doores KJ, Boutureira O, Davis BG. Site-selective traceless Staudinger ligation for glycoprotein synthesis reveals scope and limitations. Chembiochem : a European Journal of Chemical Biology. 12: 1383-6. PMID 21598371 DOI: 10.1002/Cbic.201100125  0.478
2011 Chalker JM, Bernardes GJ, Davis BG. A "tag-and-modify" approach to site-selective protein modification. Accounts of Chemical Research. 44: 730-41. PMID 21563755 DOI: 10.1021/Ar200056Q  0.602
2011 Grayson EJ, Bernardes GJ, Chalker JM, Boutureira O, Koeppe JR, Davis BG. A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates. Angewandte Chemie (International Ed. in English). 50: 4127-32. PMID 21455919 DOI: 10.1002/Anie.201006327  0.384
2011 Chalker JM, Gunnoo SB, Boutureira O, Gerstberger SC, Fernández-González M, Bernardes GJL, Griffin L, Hailu H, Schofield CJ, Davis BG. Methods for converting cysteine to dehydroalanine on peptides and proteins Chemical Science. 2: 1666-1676. DOI: 10.1039/C1Sc00185J  0.546
2010 Bernardes GJ, Kikkeri R, Maglinao M, Laurino P, Collot M, Hong SY, Lepenies B, Seeberger PH. Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting. Organic & Biomolecular Chemistry. 8: 4987-96. PMID 20820666 DOI: 10.1039/C0Ob00372G  0.517
2010 Boutureira O, D'Hooge F, Fernández-González M, Bernardes GJ, Sánchez-Navarro M, Koeppe JR, Davis BG. Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins. Chemical Communications (Cambridge, England). 46: 8142-4. PMID 20714547 DOI: 10.1039/C0Cc01576H  0.535
2010 Fernández-González M, Boutureira O, Bernardes GJL, Chalker JM, Young MA, Errey JC, Davis BG. Site-selective chemoenzymatic construction of synthetic glycoproteins using endoglycosidases Chemical Science. 1: 709-715. DOI: 10.1039/C0Sc00265H  0.718
2010 Bernardes GJL, Chalker JM, Davis BG. Chemical Protein Modification Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life. 59-91. DOI: 10.1002/9783527630516.ch3  0.508
2009 Bernardes GJ, Castagner B, Seeberger PH. Combined approaches to the synthesis and study of glycoproteins. Acs Chemical Biology. 4: 703-13. PMID 19271728 DOI: 10.1021/Cb900014N  0.463
2009 Chalker JM, Bernardes GJ, Lin YA, Davis BG. Chemical modification of proteins at cysteine: opportunities in chemistry and biology. Chemistry, An Asian Journal. 4: 630-40. PMID 19235822 DOI: 10.1002/Asia.200800427  0.558
2008 Lin YA, Chalker JM, Floyd N, Bernardes GJ, Davis BG. Allyl sulfides are privileged substrates in aqueous cross-metathesis: application to site-selective protein modification. Journal of the American Chemical Society. 130: 9642-3. PMID 18593118 DOI: 10.1021/Ja8026168  0.524
2008 Gamblin DP, van Kasteren S, Bernardes GJ, Chalker JM, Oldham NJ, Fairbanks AJ, Davis BG. Chemical site-selective prenylation of proteins. Molecular Biosystems. 4: 558-61. PMID 18493653 DOI: 10.1039/B802199F  0.697
2008 Bernardes GJ, Chalker JM, Errey JC, Davis BG. Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins. Journal of the American Chemical Society. 130: 5052-3. PMID 18357986 DOI: 10.1021/Ja800800P  0.736
2008 Bernardes GJ, Grayson EJ, Thompson S, Chalker JM, Errey JC, El Oualid F, Claridge TD, Davis BG. From disulfide- to thioether-linked glycoproteins. Angewandte Chemie (International Ed. in English). 47: 2244-7. PMID 18275052 DOI: 10.1002/Anie.200704381  0.735
2007 Bernardes GJ, Marston JP, Batsanov AS, Howard JA, Davis BG. A trisulfide-linked glycoprotein. Chemical Communications (Cambridge, England). 3145-7. PMID 17653369 DOI: 10.1039/B706682A  0.537
2006 Bernardes GJ, Gamblin DP, Davis BG. The direct formation of glycosyl thiols from reducing sugars allows one-pot protein glycoconjugation. Angewandte Chemie (International Ed. in English). 45: 4007-11. PMID 16673441 DOI: 10.1002/Anie.200600685  0.525
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