| Year |
Citation |
Score |
| 2023 |
Lareau CA, Yin Y, Maurer K, Sandor KD, Daniel B, Yagnik G, Peña J, Crawford JC, Spanjaart AM, Gutierrez JC, Haradhvala NJ, Riberdy JM, Abay T, Stickels RR, Verboon JM, ... ... Roth TL, et al. Latent human herpesvirus 6 is reactivated in CAR T cells. Nature. PMID 37938768 DOI: 10.1038/s41586-023-06704-2 |
0.456 |
|
| 2023 |
Blaeschke F, Chen YY, Apathy R, Daniel B, Chen AY, Chen PA, Sandor K, Zhang W, Li Z, Mowery CT, Yamamoto TN, Nyberg WA, To A, Yu R, Bueno R, ... ... Roth TL, et al. Modular pooled discovery of synthetic knockin sequences to program durable cell therapies. Cell. 186: 4216-4234.e33. PMID 37714135 DOI: 10.1016/j.cell.2023.08.013 |
0.798 |
|
| 2022 |
Shy BR, Vykunta VS, Ha A, Talbot A, Roth TL, Nguyen DN, Pfeifer WG, Chen YY, Blaeschke F, Shifrut E, Vedova S, Mamedov MR, Chung JJ, Li H, Yu R, et al. High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails. Nature Biotechnology. PMID 36008610 DOI: 10.1038/s41587-022-01418-8 |
0.675 |
|
| 2022 |
Carnevale J, Shifrut E, Kale N, Nyberg WA, Blaeschke F, Chen YY, Li Z, Bapat SP, Diolaiti ME, O'Leary P, Vedova S, Belk J, Daniel B, Roth TL, Bachl S, et al. RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature. PMID 36002574 DOI: 10.1038/s41586-022-05126-w |
0.815 |
|
| 2022 |
Hiatt J, Hultquist JF, McGregor MJ, Bouhaddou M, Leenay RT, Simons LM, Young JM, Haas P, Roth TL, Tobin V, Wojcechowskyj JA, Woo JM, Rathore U, Cavero DA, Shifrut E, et al. A functional map of HIV-host interactions in primary human T cells. Nature Communications. 13: 1752. PMID 35365639 DOI: 10.1038/s41467-022-29346-w |
0.756 |
|
| 2021 |
DeSilva D, Ferguson L, Chin GH, Smith BE, Apathy RA, Roth TL, Blaeschke F, Kudla M, Marson A, Ingolia NT, Cate JH. Robust T cell activation requires an eIF3-driven burst in T cell receptor translation. Elife. 10. PMID 34970966 DOI: 10.7554/eLife.74272 |
0.706 |
|
| 2021 |
Hiatt J, Cavero DA, McGregor MJ, Zheng W, Budzik JM, Roth TL, Haas KM, Wu D, Rathore U, Meyer-Franke A, Bouzidi MS, Shifrut E, Lee Y, Kumar VE, Dang EV, et al. Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins. Cell Reports. 35: 109105. PMID 33979618 DOI: 10.1016/j.celrep.2021.109105 |
0.791 |
|
| 2021 |
Lee Y, Bogdanoff D, Wang Y, Hartoularos GC, Woo JM, Mowery CT, Nisonoff HM, Lee DS, Sun Y, Lee J, Mehdizadeh S, Cantlon J, Shifrut E, Ngyuen DN, Roth TL, et al. XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment. Science Advances. 7. PMID 33883145 DOI: 10.1126/sciadv.abg4755 |
0.627 |
|
| 2021 |
Muller YD, Nguyen DP, Ferreira LMR, Ho P, Raffin C, Valencia RVB, Congrave-Wilson Z, Roth TL, Eyquem J, Van Gool F, Marson A, Perez L, Wells JA, Bluestone JA, Tang Q. The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28. Frontiers in Immunology. 12: 639818. PMID 33833759 DOI: 10.3389/fimmu.2021.639818 |
0.565 |
|
| 2021 |
Siddiqui S, Johansson K, Joo A, Bonser LR, Koh KD, Le Tonqueze O, Bolourchi S, Bautista RA, Zlock L, Roth TL, Marson A, Bhakta NR, Ansel KM, Finkbeiner WE, Erle DJ, et al. Epithelial miR-141 regulates IL-13-induced airway mucus production. Jci Insight. 6. PMID 33682796 DOI: 10.1172/jci.insight.139019 |
0.581 |
|
| 2021 |
Roth TL, Marson A. Genetic Disease and Therapy. Annual Review of Pathology. 16: 145-166. PMID 33497260 DOI: 10.1146/annurev-pathmechdis-012419-032626 |
0.581 |
|
| 2020 |
Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin CP, Matus-Nicodemos R, Hoh R, Krone MR, Hecht FM, et al. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. Jci Insight. PMID 33351785 DOI: 10.1172/jci.insight.136648 |
0.777 |
|
| 2020 |
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, ... ... Roth TL, et al. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science (New York, N.Y.). PMID 33060197 DOI: 10.1126/science.abe9403 |
0.635 |
|
| 2020 |
Schumann K, Raju SS, Lauber M, Kolb S, Shifrut E, Cortez JT, Skartsis N, Nguyen VQ, Woo JM, Roth TL, Yu R, Nguyen MLT, Simeonov DR, Nguyen DN, Targ S, et al. Functional CRISPR dissection of gene networks controlling human regulatory T cell identity. Nature Immunology. PMID 32989329 DOI: 10.1038/s41590-020-0784-4 |
0.709 |
|
| 2020 |
Cortez JT, Montauti E, Shifrut E, Gatchalian J, Zhang Y, Shaked O, Xu Y, Roth TL, Simeonov DR, Zhang Y, Chen S, Li Z, Woo JM, Ho J, Vogel IA, et al. CRISPR screen in regulatory T cells reveals modulators of Foxp3. Nature. PMID 32499641 DOI: 10.1038/S41586-020-2246-4 |
0.716 |
|
| 2020 |
Roth TL. Editing of Endogenous Genes in Cellular Immunotherapies. Current Hematologic Malignancy Reports. PMID 32415407 DOI: 10.1007/S11899-020-00587-0 |
0.424 |
|
| 2020 |
Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, ... ... Roth TL, et al. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. PMID 32353859 DOI: 10.1038/S41586-020-2286-9 |
0.669 |
|
| 2020 |
Roth TL, Li PJ, Blaeschke F, Nies JF, Apathy R, Mowery C, Yu R, Nguyen MLT, Lee Y, Truong A, Hiatt J, Wu D, Nguyen DN, Goodman D, Bluestone JA, et al. Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies. Cell. PMID 32302591 DOI: 10.1016/J.Cell.2020.03.039 |
0.807 |
|
| 2020 |
Carnevale J, Shifrut E, Tobin V, Roth T, Woo J, Bui C, Li J, Diolaiti M, Ashworth A, Marson A. Abstract PR08: Discovery of immune regulators in primary human T cells using genome-wide CRISPR screens Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-Pr08 |
0.744 |
|
| 2019 |
Nguyen DN, Roth TL, Li PJ, Chen PA, Apathy R, Mamedov MR, Vo LT, Tobin VR, Goodman D, Shifrut E, Bluestone JA, Puck JM, Szoka FC, Marson A. Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency. Nature Biotechnology. PMID 31819258 DOI: 10.1038/S41587-019-0325-6 |
0.805 |
|
| 2019 |
Ng MSF, Roth TL, Mendoza VF, Marson A, Burt TD. Helios enhances the preferential differentiation of human fetal CD4 naïve T cells into regulatory T cells. Science Immunology. 4. PMID 31757834 DOI: 10.1126/Sciimmunol.Aav5947 |
0.722 |
|
| 2019 |
Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, et al. Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells. Nature Biotechnology. PMID 31359007 DOI: 10.1038/S41587-019-0203-2 |
0.776 |
|
| 2019 |
Schober K, Müller TR, Gökmen F, Grassmann S, Effenberger M, Poltorak M, Stemberger C, Schumann K, Roth TL, Marson A, Busch DH. Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function. Nature Biomedical Engineering. PMID 31182835 DOI: 10.1038/S41551-019-0409-0 |
0.711 |
|
| 2019 |
Simeonov DR, Brandt AJ, Chan AY, Cortez JT, Li Z, Woo JM, Lee Y, Carvalho CMB, Indart AC, Roth TL, Zou J, May AP, Lupski JR, Anderson MS, Buaas FW, et al. A large CRISPR-induced bystander mutation causes immune dysregulation. Communications Biology. 2: 70. PMID 30793048 DOI: 10.1038/s42003-019-0321-x |
0.595 |
|
| 2019 |
Hultquist JF, Hiatt J, Schumann K, McGregor MJ, Roth TL, Haas P, Doudna JA, Marson A, Krogan NJ. CRISPR-Cas9 genome engineering of primary CD4 T cells for the interrogation of HIV-host factor interactions. Nature Protocols. 14: 1-27. PMID 30559373 DOI: 10.1038/S41596-018-0069-7 |
0.796 |
|
| 2019 |
Hegde B, Roth T, Nguyen D, Chheda Z, Apathy R, Marson A, Okada H. Immu-38. Crispr Based Genome Editing Of Human T Cells To Target H3.3K27M Mutation In Gliomas Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.530 |
0.464 |
|
| 2018 |
Shifrut E, Carnevale J, Tobin V, Roth TL, Woo JM, Bui CT, Li PJ, Diolaiti ME, Ashworth A, Marson A. Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function. Cell. PMID 30449619 DOI: 10.1016/J.Cell.2018.10.024 |
0.755 |
|
| 2018 |
Mocciaro A, Roth TL, Bennett HM, Soumillon M, Shah A, Hiatt J, Chapman K, Marson A, Lavieu G. Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device. Communications Biology. 1: 41. PMID 30271925 DOI: 10.1038/s42003-018-0034-6 |
0.786 |
|
| 2018 |
Roth TL, Puig-Saus C, Yu R, Shifrut E, Carnevale J, Li PJ, Hiatt J, Saco J, Krystofinski P, Li H, Tobin V, Nguyen DN, Lee MR, Putnam AL, Ferris AL, et al. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature. PMID 29995861 DOI: 10.1038/S41586-018-0326-5 |
0.819 |
|
| 2018 |
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, et al. Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 29899441 DOI: 10.1038/S41586-018-0227-7 |
0.63 |
|
| 2018 |
Farboud B, Jarvis E, Roth TL, Shin J, Corn JE, Marson A, Meyer BJ, Patel NH, Hochstrasser ML. Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms. Journal of Visualized Experiments : Jove. PMID 29889198 DOI: 10.3791/57350 |
0.7 |
|
| 2018 |
Wu CM, Roth TL, Baglaenko Y, Ferri DM, Brauer P, Zuniga-Pflucker JC, Rosbe KW, Wither JE, Marson A, Allen CDC. Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins. Journal of Immunological Methods. PMID 29614266 DOI: 10.1016/J.Jim.2018.03.009 |
0.686 |
|
| 2017 |
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/Nature23875 |
0.699 |
|
| 2016 |
Zhang Y, Roth TL, Gray EE, Chen H, Rodda LB, Liang Y, Ventura P, Villeda S, Crocker PR, Cyster JG. Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node. Elife. 5. PMID 27487469 DOI: 10.7554/Elife.18156 |
0.316 |
|
| 2015 |
Corps KN, Roth TL, McGavern DB. Inflammation and neuroprotection in traumatic brain injury. Jama Neurology. 72: 355-62. PMID 25599342 DOI: 10.1001/Jamaneurol.2014.3558 |
0.509 |
|
| 2014 |
Nayak D, Roth TL, McGavern DB. Microglia development and function. Annual Review of Immunology. 32: 367-402. PMID 24471431 DOI: 10.1146/Annurev-Immunol-032713-120240 |
0.557 |
|
| 2014 |
Roth TL, Nayak D, Atanasijevic T, Koretsky AP, Latour LL, McGavern DB. Transcranial amelioration of inflammation and cell death after brain injury. Nature. 505: 223-8. PMID 24317693 DOI: 10.1038/Nature12808 |
0.542 |
|
| 2014 |
Weiss LE, Milenkovic L, Sahl SJ, Roth TL, Scott MP, Moerner W. Single-Molecule Tracking of Smoothened in the Primary Cilium Biophysical Journal. 106: 20a. DOI: 10.1016/J.Bpj.2013.11.166 |
0.329 |
|
| 2013 |
Nayak D, Johnson KR, Heydari S, Roth TL, Zinselmeyer BH, McGavern DB. Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system. Plos Pathogens. 9: e1003395. PMID 23737750 DOI: 10.1371/Journal.Ppat.1003395 |
0.609 |
|
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