Year |
Citation |
Score |
2024 |
Downs JA, Gasser SM. Chromatin remodeling and spatial concerns in DNA double-strand break repair. Current Opinion in Cell Biology. 90: 102405. PMID 39083951 DOI: 10.1016/j.ceb.2024.102405 |
0.495 |
|
2023 |
Gasser SM, Stutz F. SUMO in the regulation of DNA repair and transcription at nuclear pores. Febs Letters. PMID 37805446 DOI: 10.1002/1873-3468.14751 |
0.441 |
|
2023 |
Gasser SM. Transient chromatin compaction in fork restart. Nature Cell Biology. PMID 37414848 DOI: 10.1038/s41556-023-01181-1 |
0.313 |
|
2021 |
Hurst V, Challa K, Jonas F, Forey R, Sack R, Seebacher J, Schmid CD, Barkai N, Shimada K, Gasser SM, Poli J. A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress. The Embo Journal. e108439. PMID 34569643 DOI: 10.15252/embj.2021108439 |
0.328 |
|
2021 |
Challa K, Seebacher J, Gasser SM. Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast. Star Protocols. 2: 100825. PMID 34568845 DOI: 10.1016/j.xpro.2021.100825 |
0.323 |
|
2021 |
Hurst V, Challa K, Shimada K, Gasser SM. Cytoskeleton integrity influences XRCC1 and PCNA dynamics at DNA damage. Molecular Biology of the Cell. mbcE20100680. PMID 34379448 DOI: 10.1091/mbc.E20-10-0680 |
0.351 |
|
2021 |
Shimada K, Tsai-Pflugfelder M, Vijeh Motlagh ND, Delgoshaie N, Fuchs J, Gut H, Gasser SM. The stabilized Pol31-Pol3 interface counteracts Pol32 ablation with differential effects on repair. Life Science Alliance. 4. PMID 34226278 DOI: 10.26508/lsa.202101138 |
0.418 |
|
2021 |
Fuchs J, Cheblal A, Gasser SM. Underappreciated Roles of DNA Polymerase δ in Replication Stress Survival. Trends in Genetics : Tig. PMID 33608117 DOI: 10.1016/j.tig.2020.12.003 |
0.403 |
|
2021 |
Challa K, Schmid CD, Kitagawa S, Cheblal A, Iesmantavicius V, Seeber A, Amitai A, Seebacher J, Hauer MH, Shimada K, Gasser SM. Damage-induced chromatome dynamics link Ubiquitin ligase and proteasome recruitment to histone loss and efficient DNA repair. Molecular Cell. PMID 33529595 DOI: 10.1016/j.molcel.2020.12.021 |
0.799 |
|
2020 |
Padeken J, Methot S, Zeller P, Delaney CE, Kalck V, Gasser SM. Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression. Genes & Development. PMID 33303642 DOI: 10.1101/gad.344234.120 |
0.306 |
|
2020 |
Forey R, Barthe A, Tittel-Elmer M, Wery M, Barrault MB, Ducrot C, Seeber A, Krietenstein N, Szachnowski U, Skrzypczak M, Ginalski K, Rowicka M, Cobb JA, Rando OJ, Soutourina J, ... ... Gasser SM, et al. A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization. Molecular Cell. PMID 33278361 DOI: 10.1016/j.molcel.2020.11.010 |
0.78 |
|
2020 |
Cheblal A, Challa K, Seeber A, Shimada K, Yoshida H, Ferreira HC, Amitai A, Gasser SM. DNA Damage-Induced Nucleosome Depletion Enhances Homology Search Independently of Local Break Movement. Molecular Cell. PMID 32970994 DOI: 10.1016/j.molcel.2020.09.002 |
0.765 |
|
2020 |
Falquet B, Ölmezer G, Enkner F, Klein D, Challa K, Appanah R, Gasser SM, Rass U. Disease-associated DNA2 nuclease-helicase protects cells from lethal chromosome under-replication. Nucleic Acids Research. PMID 32544229 DOI: 10.1093/nar/gkaa524 |
0.472 |
|
2019 |
Sasanuma H, Sakurai HSM, Furihata Y, Challa K, Palmer L, Gasser SM, Shinohara M, Shinohara A. Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis. Chromosoma. PMID 31168653 DOI: 10.1007/s00412-019-00709-5 |
0.476 |
|
2019 |
Cabianca DS, Muñoz-Jiménez C, Kalck V, Gaidatzis D, Padeken J, Seeber A, Askjaer P, Gasser SM. Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei. Nature. 569: 734-739. PMID 31118512 DOI: 10.1038/S41586-019-1243-Y |
0.742 |
|
2019 |
Hurst V, Shimada K, Gasser SM. Nuclear Actin and Actin-Binding Proteins in DNA Repair. Trends in Cell Biology. PMID 30954333 DOI: 10.1016/j.tcb.2019.02.010 |
0.41 |
|
2019 |
Gasser S. Once and Only Once. Cell. 177: 495-498. PMID 30952443 DOI: 10.1016/J.Cell.2019.03.034 |
0.404 |
|
2019 |
Hurst V, Gasser SM. The study of protein recruitment to laser-induced DNA lesions can be distorted by photoconversion of the DNA binding dye Hoechst. F1000research. 8: 104. PMID 30828443 DOI: 10.12688/f1000research.17865.2 |
0.353 |
|
2019 |
Padeken J, Zeller P, Towbin B, Katic I, Kalck V, Methot SP, Gasser SM. Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression. Genes & Development. PMID 30804228 DOI: 10.1101/gad.322495.118 |
0.379 |
|
2019 |
Hurst V, Gasser SM. The study of protein recruitment to UV-induced DNA lesions can be distorted by photoconversion of DNA dyes like Hoechst or DAPI F1000research. 8: 104. DOI: 10.12688/f1000research.17865.1 |
0.396 |
|
2018 |
Seeber A, Hauer MH, Gasser SM. Chromosome Dynamics in Response to DNA Damage. Annual Review of Genetics. PMID 30208290 DOI: 10.1146/Annurev-Genet-120417-031334 |
0.787 |
|
2018 |
Marcomini I, Shimada K, Delgoshaie N, Yamamoto I, Seeber A, Cheblal A, Horigome C, Naumann U, Gasser SM. Asymmetric Processing of DNA Ends at a Double-Strand Break Leads to Unconstrained Dynamics and Ectopic Translocation. Cell Reports. 24: 2614-2628.e4. PMID 30184497 DOI: 10.1016/J.Celrep.2018.07.102 |
0.773 |
|
2018 |
Ahringer J, Gasser SM. Repressive Chromatin in Caenorhabditis elegans: Establishment, Composition, and Function. Genetics. 208: 491-511. PMID 29378810 DOI: 10.1534/genetics.117.300386 |
0.327 |
|
2017 |
Hauer MH, Gasser SM. Chromatin and nucleosome dynamics in DNA damage and repair. Genes & Development. 31: 2204-2221. PMID 29284710 DOI: 10.1101/gad.307702.117 |
0.437 |
|
2017 |
Zeller P, Gasser SM. The Importance of Satellite Sequence Repression for Genome Stability. Cold Spring Harbor Symposia On Quantitative Biology. 82: 15-24. PMID 29133300 DOI: 10.1101/sqb.2017.82.033662 |
0.35 |
|
2017 |
Deshpande I, Seeber A, Shimada K, Keusch JJ, Gut H, Gasser SM. Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. Molecular Cell. PMID 29033322 DOI: 10.1016/J.Molcel.2017.09.019 |
0.773 |
|
2017 |
Poli J, Gasser SM, Papamichos-Chronakis M. The INO80 remodeller in transcription, replication and repair. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28847827 DOI: 10.1098/rstb.2016.0290 |
0.496 |
|
2017 |
Jeggo PA, Downs JA, Gasser SM. Chromatin modifiers and remodellers in DNA repair and signalling. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28847816 DOI: 10.1098/Rstb.2016.0279 |
0.481 |
|
2017 |
Shimada K, Gasser SM. A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage. The Journal of Cell Biology. PMID 28235945 DOI: 10.1083/jcb.201701038 |
0.364 |
|
2017 |
Amitai A, Seeber A, Gasser SM, Holcman D. Visualization of Chromatin Decompaction and Break Site Extrusion as Predicted by Statistical Polymer Modeling of Single-Locus Trajectories. Cell Reports. 18: 1200-1214. PMID 28147275 DOI: 10.1016/J.Celrep.2017.01.018 |
0.748 |
|
2017 |
Hauer MH, Seeber A, Singh V, Thierry R, Sack R, Amitai A, Kryzhanovska M, Eglinger J, Holcman D, Owen-Hughes T, Gasser SM. Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates. Nature Structural & Molecular Biology. PMID 28067915 DOI: 10.1038/Nsmb.3347 |
0.793 |
|
2016 |
Gasser SM. Selfish DNA and Epigenetic Repression Revisited. Genetics. 204: 837-839. PMID 28114097 DOI: 10.1534/genetics.116.196287 |
0.423 |
|
2016 |
Seeber A, Hegnauer AM, Hustedt N, Deshpande I, Poli J, Eglinger J, Pasero P, Gut H, Shinohara M, Hopfner KP, Shimada K, Gasser SM. RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together. Molecular Cell. PMID 27889450 DOI: 10.1016/J.Molcel.2016.10.032 |
0.755 |
|
2016 |
Seeber A, Gasser SM. Chromatin organization and dynamics in double-strand break repair. Current Opinion in Genetics & Development. 43: 9-16. PMID 27810555 DOI: 10.1016/J.Gde.2016.10.005 |
0.792 |
|
2016 |
Zeller P, Padeken J, van Schendel R, Kalck V, Tijsterman M, Gasser SM. Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability. Nature Genetics. 48: 1385-1395. PMID 27668659 DOI: 10.1038/ng.3672 |
0.385 |
|
2016 |
Gonzalez-Sandoval A, Gasser SM. On TADs and LADs: Spatial Control Over Gene Expression. Trends in Genetics : Tig. PMID 27312344 DOI: 10.1016/j.tig.2016.05.004 |
0.36 |
|
2016 |
Gasser SM. Nuclear Architecture: Past and Future Tense. Trends in Cell Biology. PMID 27177990 DOI: 10.1016/j.tcb.2016.04.011 |
0.359 |
|
2016 |
Horigome C, Bustard DE, Marcomini I, Delgoshaie N, Tsai-Pflugfelder M, Cobb JA, Gasser SM. PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL. Genes & Development. PMID 27056668 DOI: 10.1101/gad.277665.116 |
0.437 |
|
2016 |
Iwasaki D, Hayashihara K, Shima H, Higashide M, Terasawa M, Gasser SM, Shinohara M. The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation. Plos Genetics. 12: e1005942. PMID 26990569 DOI: 10.1371/journal.pgen.1005942 |
0.404 |
|
2016 |
Poli J, Gerhold CB, Tosi A, Hustedt N, Seeber A, Sack R, Herzog F, Pasero P, Shimada K, Hopfner KP, Gasser SM. Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress. Genes & Development. 30: 337-54. PMID 26798134 DOI: 10.1101/Gad.273813.115 |
0.753 |
|
2016 |
Harr JC, Gonzalez-Sandoval A, Gasser SM. Histones and histone modifications in perinuclear chromatin anchoring: from yeast to man. Embo Reports. 17: 139-55. PMID 26792937 DOI: 10.15252/embr.201541809 |
0.314 |
|
2015 |
Marcomini I, Gasser SM. Nuclear organization in DNA end processing: Telomeres vs double-strand breaks. Dna Repair. 32: 134-40. PMID 26004856 DOI: 10.1016/j.dnarep.2015.04.024 |
0.442 |
|
2015 |
Su XA, Dion V, Gasser SM, Freudenreich CH. Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability. Genes & Development. 29: 1006-17. PMID 25940904 DOI: 10.1101/gad.256404.114 |
0.462 |
|
2015 |
Horigome C, Dion V, Seeber A, Gehlen LR, Gasser SM. Visualizing the spatiotemporal dynamics of DNA damage in budding yeast. Methods in Molecular Biology (Clifton, N.J.). 1292: 77-96. PMID 25804749 DOI: 10.1007/978-1-4939-2522-3_6 |
0.773 |
|
2015 |
Hustedt N, Seeber A, Sack R, Tsai-Pflugfelder M, Bhullar B, Vlaming H, van Leeuwen F, Guénolé A, van Attikum H, Srivas R, Ideker T, Shimada K, Gasser SM. Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling. Molecular Cell. 57: 273-89. PMID 25533186 DOI: 10.1016/J.Molcel.2014.11.016 |
0.75 |
|
2015 |
Gerhold CB, Hauer MH, Gasser SM. INO80-C and SWR-C: guardians of the genome. Journal of Molecular Biology. 427: 637-51. PMID 25451604 DOI: 10.1016/j.jmb.2014.10.015 |
0.427 |
|
2014 |
Gerhold CB, Gasser SM. INO80 and SWR complexes: relating structure to function in chromatin remodeling. Trends in Cell Biology. 24: 619-31. PMID 25088669 DOI: 10.1016/j.tcb.2014.06.004 |
0.369 |
|
2014 |
Horigome C, Oma Y, Konishi T, Schmid R, Marcomini I, Hauer MH, Dion V, Harata M, Gasser SM. SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice. Molecular Cell. 55: 626-39. PMID 25066231 DOI: 10.1016/j.molcel.2014.06.027 |
0.38 |
|
2014 |
Weisman R, Cohen A, Gasser SM. TORC2-a new player in genome stability. Embo Molecular Medicine. 6: 995-1002. PMID 24992933 DOI: 10.15252/Emmm.201403959 |
0.31 |
|
2014 |
Seeber A, Dion V, Gasser SM. Remodelers move chromatin in response to DNA damage. Cell Cycle (Georgetown, Tex.). 13: 877-8. PMID 24552812 DOI: 10.4161/Cc.28200 |
0.806 |
|
2013 |
Hustedt N, Gasser SM, Shimada K. Replication checkpoint: tuning and coordination of replication forks in s phase. Genes. 4: 388-434. PMID 24705211 DOI: 10.3390/genes4030388 |
0.426 |
|
2013 |
Ferreira HC, Towbin BD, Jegou T, Gasser SM. The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery. The Journal of Cell Biology. 203: 727-35. PMID 24297748 DOI: 10.1083/jcb.201307181 |
0.347 |
|
2013 |
Nielsen I, Bentsen IB, Andersen AH, Gasser SM, Bjergbaek L. A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1. Plos One. 8: e81015. PMID 24278365 DOI: 10.1371/journal.pone.0081015 |
0.404 |
|
2013 |
Shimada K, Filipuzzi I, Stahl M, Helliwell SB, Studer C, Hoepfner D, Seeber A, Loewith R, Movva NR, Gasser SM. TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Molecular Cell. 51: 829-39. PMID 24035500 DOI: 10.1016/J.Molcel.2013.08.019 |
0.752 |
|
2013 |
Seeber A, Dion V, Gasser SM. Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage. Genes & Development. 27: 1999-2008. PMID 24029917 DOI: 10.1101/Gad.222992.113 |
0.804 |
|
2013 |
Dion V, Kalck V, Seeber A, Schleker T, Gasser SM. Cohesin and the nucleolus constrain the mobility of spontaneous repair foci. Embo Reports. 14: 984-91. PMID 24018421 DOI: 10.1038/Embor.2013.142 |
0.77 |
|
2013 |
Kueng S, Oppikofer M, Gasser SM. SIR proteins and the assembly of silent chromatin in budding yeast. Annual Review of Genetics. 47: 275-306. PMID 24016189 DOI: 10.1146/annurev-genet-021313-173730 |
0.33 |
|
2013 |
Oppikofer M, Kueng S, Gasser SM. SIR-nucleosome interactions: structure-function relationships in yeast silent chromatin. Gene. 527: 10-25. PMID 23791651 DOI: 10.1016/j.gene.2013.05.088 |
0.341 |
|
2013 |
Gonzalez-Sandoval A, Towbin BD, Gasser SM. The formation and sequestration of heterochromatin during development: delivered on 7 September 2012 at the 37th FEBS Congress in Sevilla, Spain. The Febs Journal. 280: 3212-9. PMID 23648132 DOI: 10.1111/febs.12319 |
0.323 |
|
2013 |
Dion V, Gasser SM. Chromatin movement in the maintenance of genome stability. Cell. 152: 1355-64. PMID 23498942 DOI: 10.1016/j.cell.2013.02.010 |
0.395 |
|
2013 |
Seeber A, Hauer M, Gasser SM. Nucleosome remodelers in double-strand break repair. Current Opinion in Genetics & Development. 23: 174-84. PMID 23352131 DOI: 10.1016/J.Gde.2012.12.008 |
0.77 |
|
2012 |
Taddei A, Gasser SM. Structure and function in the budding yeast nucleus. Genetics. 192: 107-29. PMID 22964839 DOI: 10.1534/genetics.112.140608 |
0.315 |
|
2012 |
Hegnauer AM, Hustedt N, Shimada K, Pike BL, Vogel M, Amsler P, Rubin SM, van Leeuwen F, Guénolé A, van Attikum H, Thomä NH, Gasser SM. An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks. The Embo Journal. 31: 3768-83. PMID 22820947 DOI: 10.1038/emboj.2012.195 |
0.346 |
|
2012 |
Kueng S, Tsai-Pflugfelder M, Oppikofer M, Ferreira HC, Roberts E, Tsai C, Roloff TC, Sack R, Gasser SM. Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic states. Plos Genetics. 8: e1002727. PMID 22654676 DOI: 10.1371/journal.pgen.1002727 |
0.356 |
|
2012 |
Shimada K, Gasser SM. DNA replication: Pif1 pulls the plug on stalled replication forks. Current Biology : Cb. 22: R404-5. PMID 22625857 DOI: 10.1016/j.cub.2012.04.015 |
0.372 |
|
2012 |
Dion V, Kalck V, Horigome C, Towbin BD, Gasser SM. Increased mobility of double-strand breaks requires Mec1, Rad9 and the homologous recombination machinery. Nature Cell Biology. 14: 502-9. PMID 22484486 DOI: 10.1038/ncb2465 |
0.493 |
|
2012 |
Neumann FR, Dion V, Gehlen LR, Tsai-Pflugfelder M, Schmid R, Taddei A, Gasser SM. Targeted INO80 enhances subnuclear chromatin movement and ectopic homologous recombination. Genes & Development. 26: 369-83. PMID 22345518 DOI: 10.1101/gad.176156.111 |
0.383 |
|
2011 |
Oppikofer M, Kueng S, Martino F, Soeroes S, Hancock SM, Chin JW, Fischle W, Gasser SM. A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. The Embo Journal. 30: 2610-21. PMID 21666601 DOI: 10.1038/Emboj.2011.170 |
0.322 |
|
2011 |
Meister P, Mango SE, Gasser SM. Locking the genome: nuclear organization and cell fate. Current Opinion in Genetics & Development. 21: 167-74. PMID 21345665 DOI: 10.1016/j.gde.2011.01.023 |
0.302 |
|
2011 |
Nagai S, Davoodi N, Gasser SM. Nuclear organization in genome stability: SUMO connections. Cell Research. 21: 474-85. PMID 21321608 DOI: 10.1038/cr.2011.31 |
0.386 |
|
2011 |
Kitada T, Schleker T, Sperling AS, Xie W, Gasser SM, Grunstein M. γH2A is a component of yeast heterochromatin required for telomere elongation. Cell Cycle (Georgetown, Tex.). 10: 293-300. PMID 21212735 DOI: 10.4161/Cc.10.2.14536 |
0.322 |
|
2011 |
Gehlen LR, Gasser SM, Dion V. How Broken DNA Finds Its Template for Repair: A Computational Approach Progress of Theoretical Physics Supplement. 191: 20-29. DOI: 10.1143/PTPS.191.20 |
0.347 |
|
2010 |
Nagai S, Heun P, Gasser SM. Roles for nuclear organization in the maintenance of genome stability. Epigenomics. 2: 289-305. PMID 22121875 DOI: 10.2217/epi.09.49 |
0.406 |
|
2010 |
Meister P, Gehlen LR, Varela E, Kalck V, Gasser SM. Visualizing yeast chromosomes and nuclear architecture. Methods in Enzymology. 470: 535-67. PMID 20946824 DOI: 10.1016/S0076-6879(10)70021-5 |
0.363 |
|
2010 |
Taddei A, Schober H, Gasser SM. The budding yeast nucleus. Cold Spring Harbor Perspectives in Biology. 2: a000612. PMID 20554704 DOI: 10.1101/cshperspect.a000612 |
0.417 |
|
2010 |
Dion V, Shimada K, Gasser SM. Actin-related proteins in the nucleus: life beyond chromatin remodelers. Current Opinion in Cell Biology. 22: 383-91. PMID 20303249 DOI: 10.1016/j.ceb.2010.02.006 |
0.452 |
|
2009 |
Bühler M, Gasser SM. Silent chromatin at the middle and ends: lessons from yeasts. The Embo Journal. 28: 2149-61. PMID 19629038 DOI: 10.1038/emboj.2009.185 |
0.41 |
|
2009 |
Schleker T, Nagai S, Gasser SM. Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. Dna Repair. 8: 1089-100. PMID 19482523 DOI: 10.1016/j.dnarep.2009.04.010 |
0.456 |
|
2009 |
Schober H, Ferreira H, Kalck V, Gehlen LR, Gasser SM. Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes & Development. 23: 928-38. PMID 19390087 DOI: 10.1101/gad.1787509 |
0.375 |
|
2009 |
van Attikum H, Gasser SM. Crosstalk between histone modifications during the DNA damage response. Trends in Cell Biology. 19: 207-17. PMID 19342239 DOI: 10.1016/j.tcb.2009.03.001 |
0.516 |
|
2009 |
Towbin BD, Meister P, Gasser SM. The nuclear envelope--a scaffold for silencing? Current Opinion in Genetics & Development. 19: 180-6. PMID 19303765 DOI: 10.1016/j.gde.2009.01.006 |
0.313 |
|
2009 |
Friedel AM, Pike BL, Gasser SM. ATR/Mec1: coordinating fork stability and repair. Current Opinion in Cell Biology. 21: 237-44. PMID 19230642 DOI: 10.1016/j.ceb.2009.01.017 |
0.44 |
|
2009 |
Martino F, Kueng S, Robinson P, Tsai-Pflugfelder M, van Leeuwen F, Ziegler M, Cubizolles F, Cockell MM, Rhodes D, Gasser SM. Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Molecular Cell. 33: 323-34. PMID 19217406 DOI: 10.1016/J.Molcel.2009.01.009 |
0.344 |
|
2009 |
Taddei A, Van Houwe G, Nagai S, Erb I, van Nimwegen E, Gasser SM. The functional importance of telomere clustering: global changes in gene expression result from SIR factor dispersion. Genome Research. 19: 611-25. PMID 19179643 DOI: 10.1101/gr.083881.108 |
0.311 |
|
2008 |
Nagai S, Dubrana K, Tsai-Pflugfelder M, Davidson MB, Roberts TM, Brown GW, Varela E, Hediger F, Gasser SM, Krogan NJ. Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (New York, N.Y.). 322: 597-602. PMID 18948542 DOI: 10.1126/Science.1162790 |
0.464 |
|
2008 |
Shimada K, Oma Y, Schleker T, Kugou K, Ohta K, Harata M, Gasser SM. Ino80 chromatin remodeling complex promotes recovery of stalled replication forks. Current Biology : Cb. 18: 566-75. PMID 18406137 DOI: 10.1016/j.cub.2008.03.049 |
0.491 |
|
2007 |
Dubrana K, van Attikum H, Hediger F, Gasser SM. The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast. Journal of Cell Science. 120: 4209-20. PMID 18003698 DOI: 10.1242/jcs.018366 |
0.386 |
|
2007 |
van Attikum H, Fritsch O, Gasser SM. Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. The Embo Journal. 26: 4113-25. PMID 17762868 DOI: 10.1038/sj.emboj.7601835 |
0.416 |
|
2007 |
Meister P, Taddei A, Ponti A, Baldacci G, Gasser SM. Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast. The Embo Journal. 26: 1315-26. PMID 17304223 DOI: 10.1038/sj.emboj.7601538 |
0.331 |
|
2007 |
Shimada K, Gasser SM. The origin recognition complex functions in sister-chromatid cohesion in Saccharomyces cerevisiae. Cell. 128: 85-99. PMID 17218257 DOI: 10.1016/j.cell.2006.11.045 |
0.368 |
|
2006 |
Meister P, Taddei A, Gasser SM. In and out of the replication factory. Cell. 125: 1233-5. PMID 16814710 DOI: 10.1016/j.cell.2006.06.014 |
0.328 |
|
2006 |
Taddei A, Gasser SM. Repairing subtelomeric DSBs at the nuclear periphery. Trends in Cell Biology. 16: 225-8. PMID 16621562 DOI: 10.1016/j.tcb.2006.03.005 |
0.404 |
|
2006 |
Cubizolles F, Martino F, Perrod S, Gasser SM. A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing. Molecular Cell. 21: 825-36. PMID 16543151 DOI: 10.1016/j.molcel.2006.02.006 |
0.301 |
|
2006 |
Rosa A, Maddocks JH, Neumann FR, Gasser SM, Stasiak A. Measuring limits of telomere movement on nuclear envelope. Biophysical Journal. 90: L24-6. PMID 16339888 DOI: 10.1529/biophysj.105.077974 |
0.314 |
|
2005 |
Cobb JA, Schleker T, Rojas V, Bjergbaek L, Tercero JA, Gasser SM. Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Genes & Development. 19: 3055-69. PMID 16357221 DOI: 10.1101/gad.361805 |
0.38 |
|
2005 |
van Attikum H, Gasser SM. The histone code at DNA breaks: a guide to repair? Nature Reviews. Molecular Cell Biology. 6: 757-65. PMID 16167054 DOI: 10.1038/nrm1737 |
0.483 |
|
2005 |
van Attikum H, Gasser SM. ATP-dependent chromatin remodeling and DNA double-strand break repair. Cell Cycle (Georgetown, Tex.). 4: 1011-4. PMID 16082209 DOI: 10.4161/cc.4.8.1887 |
0.513 |
|
2005 |
Taddei A, Gartenberg MR, Neumann FR, Hediger F, Gasser SM. Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. Novartis Foundation Symposium. 264: 140-56; discussion 1. PMID 15773752 DOI: 10.1002/0470093765.Ch10 |
0.368 |
|
2005 |
Meister P, Taddei A, Vernis L, Poidevin M, Gasser SM, Baldacci G. Temporal separation of replication and recombination requires the intra-S checkpoint. The Journal of Cell Biology. 168: 537-44. PMID 15716375 DOI: 10.1083/jcb.200410006 |
0.396 |
|
2005 |
Bjergbaek L, Cobb JA, Tsai-Pflugfelder M, Gasser SM. Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. The Embo Journal. 24: 405-17. PMID 15616582 DOI: 10.1038/sj.emboj.7600511 |
0.357 |
|
2004 |
Gartenberg MR, Neumann FR, Laroche T, Blaszczyk M, Gasser SM. Sir-mediated repression can occur independently of chromosomal and subnuclear contexts. Cell. 119: 955-67. PMID 15620354 DOI: 10.1016/J.Cell.2004.11.008 |
0.402 |
|
2004 |
van Attikum H, Fritsch O, Hohn B, Gasser SM. Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell. 119: 777-88. PMID 15607975 DOI: 10.1016/J.Cell.2004.11.033 |
0.494 |
|
2004 |
Taddei A, Hediger F, Neumann FR, Gasser SM. The function of nuclear architecture: a genetic approach. Annual Review of Genetics. 38: 305-45. PMID 15568979 DOI: 10.1146/annurev.genet.37.110801.142705 |
0.342 |
|
2004 |
Bystricky K, Heun P, Gehlen L, Langowski J, Gasser SM. Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques Proceedings of the National Academy of Sciences of the United States of America. 101: 16495-16500. PMID 15545610 DOI: 10.1073/pnas.0402766101 |
0.306 |
|
2004 |
Cobb JA, Shimada K, Gasser SM. Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response. Current Opinion in Genetics & Development. 14: 292-300. PMID 15172673 DOI: 10.1016/j.gde.2004.04.001 |
0.396 |
|
2004 |
Taddei A, Hediger F, Neumann FR, Bauer C, Gasser SM. Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. The Embo Journal. 23: 1301-12. PMID 15014445 DOI: 10.1038/sj.emboj.7600144 |
0.322 |
|
2004 |
Gilson E, Laroche T, Gasser SM. Telomeres and the functional architecture of the nucleus. Trends in Cell Biology. 3: 128-34. PMID 14731767 DOI: 10.1016/0962-8924(93)90175-Z |
0.432 |
|
2003 |
Perrod S, Gasser SM. Long-range silencing and position effects at telomeres and centromeres: parallels and differences. Cellular and Molecular Life Sciences : Cmls. 60: 2303-18. PMID 14625677 DOI: 10.1007/s00018-003-3246-x |
0.479 |
|
2003 |
Khakhar RR, Cobb JA, Bjergbaek L, Hickson ID, Gasser SM. RecQ helicases: multiple roles in genome maintenance. Trends in Cell Biology. 13: 493-501. PMID 12946629 DOI: 10.1016/S0962-8924(03)00171-5 |
0.328 |
|
2003 |
Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM. DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. The Embo Journal. 22: 4325-36. PMID 12912929 DOI: 10.1093/emboj/cdg391 |
0.465 |
|
2002 |
Shimada K, Pasero P, Gasser SM. ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes & Development. 16: 3236-52. PMID 12502744 DOI: 10.1101/gad.239802 |
0.383 |
|
2002 |
Hediger F, Dubrana K, Gasser SM. Myosin-like proteins 1 and 2 are not required for silencing or telomere anchoring, but act in the Tel1 pathway of telomere length control. Journal of Structural Biology. 140: 79-91. PMID 12490156 |
0.315 |
|
2002 |
Bjergbaek L, Cobb JA, Gasser SM. RecQ helicases and genome stability: lessons from model organisms and human disease. Swiss Medical Weekly. 132: 433-42. PMID 12457301 |
0.435 |
|
2002 |
Duncker BP, Shimada K, Tsai-Pflugfelder M, Pasero P, Gasser SM. An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing. Proceedings of the National Academy of Sciences of the United States of America. 99: 16087-92. PMID 12441400 DOI: 10.1073/pnas.252093999 |
0.321 |
|
2002 |
Cobb JA, Bjergbaek L, Gasser SM. RecQ helicases: at the heart of genetic stability. Febs Letters. 529: 43-8. PMID 12354611 DOI: 10.1016/S0014-5793(02)03269-6 |
0.325 |
|
2002 |
Pasero P, Gasser SM. In vitro DNA replication assays in yeast extracts. Methods in Enzymology. 351: 184-99. PMID 12073345 DOI: 10.1016/S0076-6879(02)51848-6 |
0.346 |
|
2001 |
Heun P, Laroche T, Shimada K, Furrer P, Gasser SM. Chromosome dynamics in the yeast interphase nucleus. Science (New York, N.Y.). 294: 2181-6. PMID 11739961 DOI: 10.1126/science.1065366 |
0.337 |
|
2001 |
Gasser SM, Cockell MM. The molecular biology of the SIR proteins. Gene. 279: 1-16. PMID 11722841 DOI: 10.1016/s0378-1119(01)00741-7 |
0.388 |
|
2001 |
Heun P, Taddei A, Gasser SM. From snapshots to moving pictures: new perspectives on nuclear organization. Trends in Cell Biology. 11: 519-25. PMID 11719059 |
0.32 |
|
2001 |
Dubrana K, Perrod S, Gasser SM. Turning telomeres off and on. Current Opinion in Cell Biology. 13: 281-9. PMID 11343898 |
0.36 |
|
2001 |
Heun P, Laroche T, Raghuraman MK, Gasser SM. The positioning and dynamics of origins of replication in the budding yeast nucleus. The Journal of Cell Biology. 152: 385-400. PMID 11266454 DOI: 10.1083/jcb.152.2.385 |
0.322 |
|
2001 |
Perrod S, Cockell MM, Laroche T, Renauld H, Ducrest AL, Bonnard C, Gasser SM. A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. The Embo Journal. 20: 197-209. PMID 11226170 DOI: 10.1093/emboj/20.1.197 |
0.307 |
|
2000 |
Frei C, Gasser SM. RecQ-like helicases: the DNA replication checkpoint connection. Journal of Cell Science. 113: 2641-6. PMID 10893179 |
0.381 |
|
2000 |
Laroche T, Martin SG, Tsai-Pflugfelder M, Gasser SM. The dynamics of yeast telomeres and silencing proteins through the cell cycle. Journal of Structural Biology. 129: 159-74. PMID 10806066 DOI: 10.1006/Jsbi.2000.4240 |
0.318 |
|
2000 |
Frei C, Gasser SM. The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci. Genes & Development. 14: 81-96. PMID 10640278 |
0.418 |
|
1999 |
Pasero P, Duncker BP, Gasser SM. In vitro DNA replication in yeast nuclear extracts. Methods (San Diego, Calif.). 18: 368-76, 323. PMID 10454998 DOI: 10.1006/METH.1999.0794 |
0.414 |
|
1999 |
Martin SG, Laroche T, Suka N, Grunstein M, Gasser SM. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell. 97: 621-33. PMID 10367891 DOI: 10.1016/S0092-8674(00)80773-4 |
0.481 |
|
1998 |
Akhmedov AT, Frei C, Tsai-Pflugfelder M, Kemper B, Gasser SM, Jessberger R. Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure. The Journal of Biological Chemistry. 273: 24088-94. PMID 9727028 DOI: 10.1074/jbc.273.37.24088 |
0.438 |
|
1998 |
Cockell M, Renauld H, Watt P, Gasser SM. Sif2p interacts with Sir4p amino-terminal domain and antagonizes telomeric silencing in yeast. Current Biology : Cb. 8: 787-90. PMID 9651685 DOI: 10.1016/S0960-9822(98)70304-5 |
0.333 |
|
1998 |
Pasero P, Gasser SM. New systems for replicating DNA in vitro. Current Opinion in Cell Biology. 10: 304-10. PMID 9640529 DOI: 10.1016/S0955-0674(98)80004-5 |
0.418 |
|
1998 |
Laroche T, Martin SG, Gotta M, Gorham HC, Pryde FE, Louis EJ, Gasser SM. Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Current Biology : Cb. 8: 653-6. PMID 9635192 DOI: 10.1016/S0960-9822(98)70252-0 |
0.408 |
|
1998 |
Jessberger R, Frei C, Gasser SM. Chromosome dynamics: the SMC protein family. Current Opinion in Genetics & Development. 8: 254-9. PMID 9610418 DOI: 10.1016/S0959-437X(98)80149-4 |
0.344 |
|
1998 |
Gasser SM, Gotta M, Renauld H, Laroche T, Cockell M. Nuclear organization and silencing: trafficking of Sir proteins. Novartis Foundation Symposium. 214: 114-26; discussion 1. PMID 9601014 DOI: 10.1002/9780470515501.CH7 |
0.327 |
|
1998 |
Gasser SM, Paro R, Stewart F, Aasland R. The genetics of epigenetics. Cellular and Molecular Life Sciences : Cmls. 54: 1-5. PMID 9487382 |
0.35 |
|
1998 |
Pasero P, Heu P, Duncker B, Braguglia D, Gasser S. In vitro DNA synthesis: Subnuclear targeting of cell-cycle regulated kinases regulate ORC-dependent replication in isolated yeast nuclei Biology of the Cell. 90: 88-107. DOI: 10.1016/S0248-4900(98)80235-9 |
0.346 |
|
1998 |
Braguglia D, Heun P, Pasero P, Duncker B, Gasser S. Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template 1 1Edited by M. Yaniv Journal of Molecular Biology. 281: 631-649. DOI: 10.1006/JMBI.1998.1973 |
0.359 |
|
1997 |
Pasero P, Braguglia D, Gasser SM. ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei. Genes & Development. 11: 1504-18. PMID 9203578 DOI: 10.1101/GAD.11.12.1504 |
0.398 |
|
1997 |
Gotta M, Gasser SM. Nuclear organization and transcriptional silencing in yeast. Experientia. 52: 1136-47. PMID 8988257 DOI: 10.1007/BF01952113 |
0.355 |
|
1996 |
Gotta M, Laroche T, Formenton A, Maillet L, Scherthan H, Gasser SM. The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae. The Journal of Cell Biology. 134: 1349-63. PMID 8830766 DOI: 10.1083/Jcb.134.6.1349 |
0.382 |
|
1995 |
Grunstein M, Hecht A, Fisher-Adams G, Wan J, Mann RK, Strahl-Bolsinger S, Laroche T, Gasser S. The regulation of euchromatin and heterochromatin by histones in yeast. Journal of Cell Science. Supplement. 19: 29-36. PMID 8655644 DOI: 10.1242/Jcs.1995.Supplement_19.4 |
0.363 |
|
1995 |
Müller T, Gilson E, Schmidt R, Giraldo R, Sogo J, Gross H, Gasser SM. Imaging the asymmetrical DNA bend induced by repressor activator protein 1 with scanning tunneling microscopy. Journal of Structural Biology. 113: 1-12. PMID 7880649 DOI: 10.1006/JSBI.1994.1027 |
0.392 |
|
1995 |
Gilson E, Müller T, Sogo J, Laroche T, Gasser SM. RAP1 stimulates single- to double-strand association of yeast telomeric DNA: implications for telomere-telomere interactions. Nucleic Acids Research. 22: 5310-20. PMID 7816621 DOI: 10.1093/NAR/22.24.5310 |
0.426 |
|
1994 |
Dang Q, Alghisi GC, Gasser SM. Phosphorylation of the C-terminal domain of yeast topoisomerase II by casein kinase II affects DNA-protein interaction Journal of Molecular Biology. 243: 10-24. PMID 7932731 DOI: 10.1006/jmbi.1994.1626 |
0.327 |
|
1993 |
Gilson E, Roberge M, Giraldo R, Rhodes D, Gasser SM. Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites. Journal of Molecular Biology. 231: 293-310. PMID 8510148 DOI: 10.1006/Jmbi.1993.1283 |
0.436 |
|
1992 |
Roberge M, Gasser SM. DNA loops: structural and functional properties of scaffold-attached regions. Molecular Microbiology. 6: 419-23. PMID 1560771 DOI: 10.1111/j.1365-2958.1992.tb01485.x |
0.478 |
|
1991 |
Gasser SM. Replication origins, factors and attachment sites. Current Opinion in Cell Biology. 3: 407-13. PMID 1892651 |
0.379 |
|
1991 |
Raska I, Michel LS, Jarnik M, Dundr M, Fakan S, Gasser S, Gassmann M, Hubscher U, Izaurralde E, Martinez E, Richter A, Dubochet J. Ultrastructural cryoimmunocytochemistry is a convenient tool for the study of DNA replication in cultured cells Journal of Electron Microscopy Technique. 18: 91-105. PMID 1886006 DOI: 10.1002/Jemt.1060180202 |
0.469 |
|
1990 |
Amati B, Pick L, Laroche T, Gasser SM. Nuclear scaffold attachment stimulates, but is not essential for ARS activity in Saccharomyces cerevisiae: analysis of the Drosophila ftz SAR. The Embo Journal. 9: 4007-16. PMID 2123454 DOI: 10.1002/J.1460-2075.1990.Tb07622.X |
0.399 |
|
1990 |
Amati B, Gasser SM. Drosophila scaffold-attached regions bind nuclear scaffolds and can function as ARS elements in both budding and fission yeasts. Molecular and Cellular Biology. 10: 5442-54. PMID 2118998 DOI: 10.1128/mcb.10.10.5442-5454.1990 |
0.346 |
|
1989 |
Hofmann JF, Laroche T, Brand AH, Gasser SM. RAP-1 factor is necessary for DNA loop formation in vitro at the silent mating type locus HML. Cell. 57: 725-37. PMID 2655930 DOI: 10.1016/0092-8674(89)90788-5 |
0.351 |
|
1988 |
Mirkovitch J, Gasser SM, Laemmli UK. Scaffold attachment of DNA loops in metaphase chromosomes. Journal of Molecular Biology. 200: 101-9. PMID 3132557 DOI: 10.1016/0022-2836(88)90336-1 |
0.687 |
|
1988 |
Amati BB, Gasser SM. Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold. Cell. 54: 967-78. PMID 2843296 DOI: 10.1016/0092-8674(88)90111-0 |
0.332 |
|
1987 |
Gasser SM, Laemmli UK. Improved methods for the isolation of individual and clustered mitotic chromosomes. Experimental Cell Research. 173: 85-98. PMID 3678386 DOI: 10.1016/0014-4827(87)90334-X |
0.614 |
|
1987 |
Mirkovitch J, Gasser SM, Laemmli UK. Relation of chromosome structure and gene expression. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 317: 563-74. PMID 2894689 DOI: 10.1098/Rstb.1987.0081 |
0.634 |
|
1987 |
Gasser S, Laemmli U. A glimpse at chromosomal order Trends in Genetics. 3: 16-22. DOI: 10.1016/0168-9525(87)90156-9 |
0.666 |
|
1986 |
Gasser SM, Laemmli UK. The organisation of chromatin loops: characterization of a scaffold attachment site. The Embo Journal. 5: 511-8. PMID 16453673 DOI: 10.1002/J.1460-2075.1986.Tb04240.X |
0.648 |
|
1986 |
Gasser SM, Laroche T, Falquet J, Boy de la Tour E, Laemmli UK. Metaphase chromosome structure. Involvement of topoisomerase II. Journal of Molecular Biology. 188: 613-29. PMID 3016287 DOI: 10.1016/S0022-2836(86)80010-9 |
0.663 |
|
1986 |
Gasser SM, Laemmli UK. Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster. Cell. 46: 521-30. PMID 3015418 DOI: 10.1016/0092-8674(86)90877-9 |
0.624 |
|
1983 |
Riezman H, Hay R, Gasser S, Daum G, Schneider G, Witte C, Schatz G. The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles. The Embo Journal. 2: 1105-11. PMID 16453466 DOI: 10.1002/J.1460-2075.1983.Tb01553.X |
0.579 |
|
1983 |
Gasser SM, Schatz G. Import of proteins into mitochondria. In vitro studies on the biogenesis of the outer membrane. The Journal of Biological Chemistry. 258: 3427-30. PMID 6339485 |
0.431 |
|
1982 |
Gasser SM, Ohashi A, Daum G, Böhni PC, Gibson J, Reid GA, Yonetani T, Schatz G. Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps Proceedings of the National Academy of Sciences of the United States of America. 79: 267-271. PMID 7043457 DOI: 10.1073/Pnas.79.2.267 |
0.401 |
|
1982 |
Daum G, Gasser SM, Schatz G. Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. The Journal of Biological Chemistry. 257: 13075-80. PMID 6752147 |
0.394 |
|
1982 |
Gasser SM, Daum G, Schatz G. Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria. The Journal of Biological Chemistry. 257: 13034-41. PMID 6215405 |
0.385 |
|
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