| Year |
Citation |
Score |
| 2021 |
Franz A, Valledor P, Ubieto-Capella P, Pilger D, Galarreta A, Lafarga V, Fernández-Llorente A, de la Vega-Barranco G, den Brave F, Hoppe T, Fernandez-Capetillo O, Lecona E. USP7 and VCP define the SUMO/Ubiquitin landscape at the DNA replication fork. Cell Reports. 37: 109819. PMID 34644576 DOI: 10.1016/j.celrep.2021.109819 |
0.535 |
|
| 2021 |
Galarreta A, Valledor P, Fernandez-Capetillo O, Lecona E. Coordinating DNA Replication and Mitosis through Ubiquitin/SUMO and CDK1. International Journal of Molecular Sciences. 22. PMID 34445496 DOI: 10.3390/ijms22168796 |
0.56 |
|
| 2021 |
Galindo-Campos MA, Lutfi N, Bonnin S, Martínez C, Velasco-Hernandez T, García-Hernández V, Martin-Caballero J, Ampurdanés C, Gimeno R, Colomo L, Roue G, Guilbaud G, Dantzer F, Navarro P, Murga M, ... Fernandez-Capetillo O, et al. Distinct roles for PARP-1 and PARP-2 in c-Myc-driven B-cell lymphoma in mice. Blood. PMID 34359075 DOI: 10.1182/blood.2021012805 |
0.333 |
|
| 2021 |
Lafarga V, Sirozh O, Díaz-López I, Galarreta A, Hisaoka M, Zarzuela E, Boskovic J, Jovanovic B, Fernandez-Leiro R, Muñoz J, Stoecklin G, Ventoso I, Fernandez-Capetillo O. Widespread displacement of DNA- and RNA-binding factors underlies toxicity of arginine-rich cell-penetrating peptides. The Embo Journal. e103311. PMID 33978236 DOI: 10.15252/embj.2019103311 |
0.336 |
|
| 2021 |
Galarreta A, Valledor P, Ubieto-Capella P, Lafarga V, Zarzuela E, Muñoz J, Malumbres M, Lecona E, Fernandez-Capetillo O. USP7 limits CDK1 activity throughout the cell cycle. The Embo Journal. e99692. PMID 33856059 DOI: 10.15252/embj.201899692 |
0.386 |
|
| 2020 |
Atashpaz S, Samadi Shams S, Gonzalez JM, Sebestyén E, Arghavanifard N, Gnocchi A, Albers E, Minardi S, Faga G, Soffientini P, Allievi E, Cancila V, Bachi A, Fernández-Capetillo Ó, Tripodo C, et al. ATR expands embryonic stem cell fate potential in response to replication stress. Elife. 9. PMID 32163370 DOI: 10.7554/Elife.54756 |
0.423 |
|
| 2018 |
Lafarga V, Sung HM, Haneke K, Roessig L, Pauleau AL, Bruer M, Rodriguez-Acebes S, Lopez-Contreras AJ, Gruss OJ, Erhardt S, Mendez J, Fernandez-Capetillo O, Stoecklin G. TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress. Embo Reports. PMID 30538118 DOI: 10.15252/Embr.201846224 |
0.441 |
|
| 2018 |
Pacheco S, Maldonado-Linares A, Marcet-Ortega M, Rojas C, Martínez-Marchal A, Fuentes-Lazaro J, Lange J, Jasin M, Keeney S, Fernández-Capetillo O, Garcia-Caldés M, Roig I. ATR is required to complete meiotic recombination in mice. Nature Communications. 9: 2622. PMID 29977027 DOI: 10.1038/S41467-018-04851-Z |
0.578 |
|
| 2018 |
Lecona E, Fernandez-Capetillo O. Targeting ATR in cancer. Nature Reviews. Cancer. 18: 586-595. PMID 29899559 DOI: 10.1038/S41568-018-0034-3 |
0.435 |
|
| 2017 |
Olbrich T, Mayor-Ruiz C, Vega-Sendino M, Gomez C, Ortega S, Ruiz S, Fernandez-Capetillo O. A p53-dependent response limits the viability of mammalian haploid cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808015 DOI: 10.1073/Pnas.1705133114 |
0.342 |
|
| 2017 |
Ruiz S, Mayor-Ruiz C, Lafarga V, Murga M, Vega M, Ortega S, Fernandez-Capetillo O. Abstract PR15: Cas9/RNA-based forward genetic screenings in mouse embryonic stem cells uncovered the role of genes mediating resistance to ATR inhibitors Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-Pr15 |
0.378 |
|
| 2017 |
Chaudhuri AR, Callen E, Ding X, Gogola E, Duarte AA, Lee J, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, ... ... Fernandez-Capetillo O, et al. Abstract IA09: Replication fork stability confers chemoresistance in BRCA-deficient cells Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-Ia09 |
0.731 |
|
| 2016 |
Chaudhuri AR, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, ... ... Fernandez-Capetillo O, et al. Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature. PMID 27680696 DOI: 10.1038/nature19826 |
0.554 |
|
| 2016 |
Lecona E, Fernandez-Capetillo O. A SUMO and ubiquitin code coordinates protein traffic at replication factories. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 38: 1209-1217. PMID 27667742 DOI: 10.1002/Bies.201600129 |
0.521 |
|
| 2016 |
Morgado-Palacin I, Day A, Murga M, Lafarga V, Anton ME, Tubbs A, Chen HT, Ergan A, Anderson R, Bhandoola A, Pike KG, Barlaam B, Cadogan E, Wang X, Pierce AJ, ... ... Fernandez-Capetillo O, et al. Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML. Science Signaling. 9: ra91. PMID 27625305 DOI: 10.1126/Scisignal.Aad8243 |
0.708 |
|
| 2016 |
Nieto-Soler M, Morgado-Palacin I, Lafarga V, Lecona E, Murga M, Callen E, Azorin D, Alonso J, Lopez-Contreras AJ, Nussenzweig A, Fernandez-Capetillo O. Efficacy of ATR inhibitors as single agents in Ewing sarcoma. Oncotarget. 7: 58759-58767. PMID 27577084 DOI: 10.18632/Oncotarget.11643 |
0.634 |
|
| 2016 |
Murga M, Lecona E, Kamileri I, Díaz M, Lugli N, Sotiriou SK, Anton ME, Méndez J, Halazonetis TD, Fernandez-Capetillo O. POLD3 Is Haploinsufficient for DNA Replication in Mice. Molecular Cell. PMID 27524497 DOI: 10.1016/J.Molcel.2016.07.007 |
0.607 |
|
| 2016 |
Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, ... ... Fernandez-Capetillo O, et al. Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature. 535: 382-7. PMID 27443740 DOI: 10.1038/Nature18325 |
0.735 |
|
| 2016 |
Ruiz S, Mayor-Ruiz C, Lafarga V, Murga M, Vega-Sendino M, Ortega S, Fernandez-Capetillo O. A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors. Molecular Cell. 62: 307-13. PMID 27067599 DOI: 10.1016/J.Molcel.2016.03.006 |
0.4 |
|
| 2016 |
Lecona E, Rodriguez-Acebes S, Specks J, Lopez-Contreras AJ, Ruppen I, Murga M, Muñoz J, Mendez J, Fernandez-Capetillo O. USP7 is a SUMO deubiquitinase essential for DNA replication. Nature Structural & Molecular Biology. 23: 270-7. PMID 26950370 DOI: 10.1038/Nsmb.3185 |
0.618 |
|
| 2015 |
Ruiz S, Fernandez-Capetillo O. Reducing genomic instability in iPSCs. Oncotarget. 6: 34045-6. PMID 26550804 DOI: 10.18632/Oncotarget.6212 |
0.38 |
|
| 2015 |
Alvarez S, Díaz M, Flach J, Rodriguez-Acebes S, López-Contreras AJ, Martínez D, Cañamero M, Fernández-Capetillo O, Isern J, Passegué E, Méndez J. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nature Communications. 6: 8548. PMID 26456157 DOI: 10.1038/Ncomms9548 |
0.428 |
|
| 2015 |
Ruiz S, Lopez-Contreras AJ, Gabut M, Marion RM, Gutierrez-Martinez P, Bua S, Ramirez O, Olalde I, Rodrigo-Perez S, Li H, Marques-Bonet T, Serrano M, Blasco MA, Batada NN, Fernandez-Capetillo O. Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells. Nature Communications. 6: 8036. PMID 26292731 DOI: 10.1038/Ncomms9036 |
0.424 |
|
| 2015 |
Specks J, Lecona E, Lopez-Contreras AJ, Fernandez-Capetillo O. A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development. Molecular and Cellular Biology. 35: 2910-7. PMID 26077802 DOI: 10.1128/Mcb.00475-15 |
0.356 |
|
| 2015 |
Lopez-Contreras AJ, Specks J, Barlow JH, Ambrogio C, Desler C, Vikingsson S, Rodrigo-Perez S, Green H, Rasmussen LJ, Murga M, Nussenzweig A, Fernandez-Capetillo O. Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice. Genes & Development. 29: 690-5. PMID 25838540 DOI: 10.1101/Gad.256958.114 |
0.582 |
|
| 2015 |
Specks J, Nieto-Soler M, Lopez-Contreras AJ, Fernandez-Capetillo O. Modeling the study of DNA damage responses in mice. Methods in Molecular Biology (Clifton, N.J.). 1267: 413-37. PMID 25636482 DOI: 10.1007/978-1-4939-2297-0_21 |
0.521 |
|
| 2014 |
Lecona E, Fernández-Capetillo O. Replication stress and cancer: it takes two to tango. Experimental Cell Research. 329: 26-34. PMID 25257608 DOI: 10.1016/J.Yexcr.2014.09.019 |
0.424 |
|
| 2014 |
Ruiz S, Fernandez-Capetillo O. The maternal side of Fanconi Anemia. Molecular Cell. 55: 803-804. PMID 25238193 DOI: 10.1016/J.Molcel.2014.08.029 |
0.371 |
|
| 2014 |
Winter GE, Radic B, Mayor-Ruiz C, Blomen VA, Trefzer C, Kandasamy RK, Huber KV, Gridling M, Chen D, Klampfl T, Kralovics R, Kubicek S, Fernandez-Capetillo O, Brummelkamp TR, Superti-Furga G. The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity. Nature Chemical Biology. 10: 768-73. PMID 25064833 DOI: 10.1038/Nchembio.1590 |
0.508 |
|
| 2014 |
Schulze J, Lopez-Contreras AJ, Uluçkan Ö, Graña-Castro O, Fernandez-Capetillo O, Wagner EF. Fos-dependent induction of Chk1 protects osteoblasts from replication stress. Cell Cycle (Georgetown, Tex.). 13: 1980-6. PMID 24762558 DOI: 10.4161/Cc.28923 |
0.422 |
|
| 2014 |
Juan D, Rico D, Marques-Bonet T, Fernández-Capetillo O, Valencia A. Late-replicating CNVs as a source of new genes. Biology Open. 3. PMID 24596403 DOI: 10.1242/Bio.20147815 |
0.39 |
|
| 2014 |
Eguren M, Ãlvarez-Fernández M, GarcÃa F, López-Contreras AJ, Fujimitsu K, Yaguchi H, Luque-GarcÃa JL, Fernández-Capetillo O, Muñoz J, Yamano H, Malumbres M. A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens. Cell Reports. 6: 670-83. PMID 24508461 DOI: 10.1016/J.Celrep.2014.01.017 |
0.425 |
|
| 2014 |
Arcas A, Fernández-Capetillo O, Cases I, Rojas AM. Emergence and evolutionary analysis of the human DDR network: implications in comparative genomics and downstream analyses. Molecular Biology and Evolution. 31: 940-61. PMID 24441036 DOI: 10.1093/Molbev/Msu046 |
0.358 |
|
| 2014 |
Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM. p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia. Oncogene. 33: 4599-612. PMID 24121270 DOI: 10.1038/Onc.2013.417 |
0.379 |
|
| 2013 |
Lecona E, Rojas LA, Bonasio R, Johnston A, Fernández-Capetillo O, Reinberg D. Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes. Plos Biology. 11: e1001737. PMID 24358021 DOI: 10.1371/Journal.Pbio.1001737 |
0.356 |
|
| 2013 |
Fernandez-Capetillo O, Nussenzweig A. Naked replication forks break apRPArt. Cell. 155: 979-80. PMID 24267882 DOI: 10.1016/J.Cell.2013.10.049 |
0.693 |
|
| 2013 |
Callen E, Di Virgilio M, Kruhlak MJ, Nieto-Soler M, Wong N, Chen HT, Faryabi RB, Polato F, Santos M, Starnes LM, Wesemann DR, Lee JE, Tubbs A, Sleckman BP, Daniel JA, ... ... Fernandez-Capetillo O, et al. 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions. Cell. 153: 1266-80. PMID 23727112 DOI: 10.1016/J.Cell.2013.05.023 |
0.816 |
|
| 2013 |
Monasor A, Murga M, Lopez-Contreras AJ, Navas C, Gomez G, Pisano DG, Fernandez-Capetillo O. INK4a/ARF limits the expansion of cells suffering from replication stress. Cell Cycle (Georgetown, Tex.). 12: 1948-54. PMID 23676215 DOI: 10.4161/Cc.25017 |
0.423 |
|
| 2013 |
Lopez-Contreras AJ, Ruppen I, Nieto-Soler M, Murga M, Rodriguez-Acebes S, Remeseiro S, Rodrigo-Perez S, Rojas AM, Mendez J, Muñoz J, Fernandez-Capetillo O. A proteomic characterization of factors enriched at nascent DNA molecules. Cell Reports. 3: 1105-16. PMID 23545495 DOI: 10.1016/J.Celrep.2013.03.009 |
0.557 |
|
| 2013 |
Barlow JH, Faryabi RB, Callén E, Wong N, Malhowski A, Chen HT, Gutierrez-Cruz G, Sun HW, McKinnon P, Wright G, Casellas R, Robbiani DF, Staudt L, Fernandez-Capetillo O, Nussenzweig A. Identification of early replicating fragile sites that contribute to genome instability. Cell. 152: 620-32. PMID 23352430 DOI: 10.1016/J.Cell.2013.01.006 |
0.815 |
|
| 2013 |
Marqués-Torrejón MÁ, Porlan E, Banito A, Gómez-Ibarlucea E, Lopez-Contreras AJ, Fernández-Capetillo O, Vidal A, Gil J, Torres J, Fariñas I. Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression. Cell Stem Cell. 12: 88-100. PMID 23260487 DOI: 10.1016/J.Stem.2012.12.001 |
0.358 |
|
| 2012 |
Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A. BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. Molecular Cell. 46: 125-35. PMID 22445484 DOI: 10.1016/J.Molcel.2012.02.015 |
0.835 |
|
| 2012 |
López-Contreras AJ, Gutierrez-Martinez P, Specks J, Rodrigo-Perez S, Fernandez-Capetillo O. An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation. The Journal of Experimental Medicine. 209: 455-61. PMID 22370720 DOI: 10.1084/Jem.20112147 |
0.425 |
|
| 2012 |
Schoppy DW, Ragland RL, Gilad O, Shastri N, Peters AA, Murga M, Fernandez-Capetillo O, Diehl JA, Brown EJ. Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR. The Journal of Clinical Investigation. 122: 241-52. PMID 22133876 DOI: 10.1172/Jci58928 |
0.396 |
|
| 2012 |
Fernandez-Capetillo O. Abstract SY23-03: Exploiting oncogene-induced replicative stress for the targeting of cancer cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy23-03 |
0.316 |
|
| 2011 |
Murga M, Campaner S, Lopez-Contreras AJ, Toledo LI, Soria R, Montaña MF, D'Artista L, Schleker T, Guerra C, Garcia E, Barbacid M, Hidalgo M, Amati B, Fernandez-Capetillo O. Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors. Nature Structural & Molecular Biology. 18: 1331-5. PMID 22120667 DOI: 10.1038/Nsmb.2189 |
0.351 |
|
| 2011 |
Choi S, Toledo LI, Fernandez-Capetillo O, Bakkenist CJ. CGK733 does not inhibit ATM or ATR kinase activity in H460 human lung cancer cells. Dna Repair. 10: 1000-1; author reply. PMID 21865098 DOI: 10.1016/J.Dnarep.2011.07.013 |
0.368 |
|
| 2011 |
Toledo LI, Murga M, Fernandez-Capetillo O. Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs. Molecular Oncology. 5: 368-73. PMID 21820372 DOI: 10.1016/J.Molonc.2011.07.002 |
0.442 |
|
| 2011 |
Toledo LI, Murga M, Zur R, Soria R, Rodriguez A, Martinez S, Oyarzabal J, Pastor J, Bischoff JR, Fernandez-Capetillo O. A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. Nature Structural & Molecular Biology. 18: 721-7. PMID 21552262 DOI: 10.1038/Nsmb.2076 |
0.486 |
|
| 2011 |
Blasco MA, Serrano M, Fernandez-Capetillo O. Genomic instability in iPS: time for a break. The Embo Journal. 30: 991-3. PMID 21407252 DOI: 10.1038/Emboj.2011.50 |
0.31 |
|
| 2010 |
Vogler C, Huber C, Waldmann T, Ettig R, Braun L, Izzo A, Daujat S, Chassignet I, Lopez-Contreras AJ, Fernandez-Capetillo O, Dundr M, Rippe K, Längst G, Schneider R. Histone H2A C-terminus regulates chromatin dynamics, remodeling, and histone H1 binding. Plos Genetics. 6: e1001234. PMID 21170357 DOI: 10.1371/Journal.Pgen.1001234 |
0.313 |
|
| 2010 |
López-Contreras AJ, Fernandez-Capetillo O. The ATR barrier to replication-born DNA damage. Dna Repair. 9: 1249-55. PMID 21036674 DOI: 10.1016/J.Dnarep.2010.09.012 |
0.601 |
|
| 2010 |
Herranz D, Muñoz-Martin M, Cañamero M, Mulero F, Martinez-Pastor B, Fernandez-Capetillo O, Serrano M. Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nature Communications. 1: 3. PMID 20975665 DOI: 10.1038/Ncomms1001 |
0.366 |
|
| 2010 |
Santos MA, Huen MS, Jankovic M, Chen HT, López-Contreras AJ, Klein IA, Wong N, Barbancho JL, Fernandez-Capetillo O, Nussenzweig MC, Chen J, Nussenzweig A. Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8. The Journal of Experimental Medicine. 207: 973-81. PMID 20385748 DOI: 10.1084/Jem.20092308 |
0.697 |
|
| 2010 |
Kumar A, Fernandez-Capetillo O, Fernadez-Capetillo O, Carrera AC. Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair. Proceedings of the National Academy of Sciences of the United States of America. 107: 7491-6. PMID 20368419 DOI: 10.1073/Pnas.0914242107 |
0.584 |
|
| 2010 |
Bunting SF, Callén E, Wong N, Chen HT, Polato F, Gunn A, Bothmer A, Feldhahn N, Fernandez-Capetillo O, Cao L, Xu X, Deng CX, Finkel T, Nussenzweig M, Stark JM, et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell. 141: 243-54. PMID 20362325 DOI: 10.1016/J.Cell.2010.03.012 |
0.75 |
|
| 2010 |
McNees CJ, Tejera AM, Martínez P, Murga M, Mulero F, Fernandez-Capetillo O, Blasco MA. ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase. The Journal of Cell Biology. 188: 639-52. PMID 20212315 DOI: 10.1083/Jcb.200908136 |
0.521 |
|
| 2010 |
Campaner S, Doni M, Hydbring P, Verrecchia A, Bianchi L, Sardella D, Schleker T, Perna D, Tronnersjö S, Murga M, Fernandez-Capetillo O, Barbacid M, Larsson LG, Amati B. Cdk2 suppresses cellular senescence induced by the c-myc oncogene. Nature Cell Biology. 12: 54-9; sup pp 1-14. PMID 20010815 DOI: 10.1038/Ncb2004 |
0.443 |
|
| 2010 |
Fernandez-Capetillo O. Intrauterine programming of ageing. Embo Reports. 11: 32-6. PMID 20010800 DOI: 10.1038/embor.2009.262 |
0.375 |
|
| 2009 |
Cerqueira A, SantamarÃa D, MartÃnez-Pastor B, Cuadrado M, Fernández-Capetillo O, Barbacid M. Overall Cdk activity modulates the DNA damage response in mammalian cells. The Journal of Cell Biology. 187: 773-80. PMID 19995934 DOI: 10.1083/Jcb.200903033 |
0.569 |
|
| 2009 |
Cuadrado M, Gutierrez-Martinez P, Swat A, Nebreda AR, Fernandez-Capetillo O. p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage. Cancer Research. 69: 8726-32. PMID 19843869 DOI: 10.1158/0008-5472.Can-09-0729 |
0.584 |
|
| 2009 |
Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, McNees C, Flores JM, Fernández-Capetillo O, Tarsounas M, Blasco MA. Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes & Development. 23: 2060-75. PMID 19679647 DOI: 10.1101/Gad.543509 |
0.519 |
|
| 2009 |
Marión RM, Strati K, Li H, Murga M, Blanco R, Ortega S, Fernandez-Capetillo O, Serrano M, Blasco MA. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature. 460: 1149-53. PMID 19668189 DOI: 10.1038/Nature08287 |
0.61 |
|
| 2009 |
Murga M, Bunting S, Montaña MF, Soria R, Mulero F, Cañamero M, Lee Y, McKinnon PJ, Nussenzweig A, Fernandez-Capetillo O. A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. Nature Genetics. 41: 891-8. PMID 19620979 DOI: 10.1038/Ng.420 |
0.641 |
|
| 2009 |
Lafarga V, Cuadrado A, Lopez de Silanes I, Bengoechea R, Fernandez-Capetillo O, Nebreda AR. p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint. Molecular and Cellular Biology. 29: 4341-51. PMID 19528229 DOI: 10.1128/Mcb.00210-09 |
0.403 |
|
| 2009 |
Efeyan A, Murga M, Martinez-Pastor B, Ortega-Molina A, Soria R, Collado M, Fernandez-Capetillo O, Serrano M. Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression. Plos One. 4: e5475. PMID 19421407 DOI: 10.1371/Journal.Pone.0005475 |
0.539 |
|
| 2008 |
Fernandez-Capetillo O, Nussenzweig A. ATM breaks into heterochromatin. Molecular Cell. 31: 303-4. PMID 18691960 DOI: 10.1016/J.Molcel.2008.07.004 |
0.721 |
|
| 2008 |
Fernandez-Capetillo O, Murga M. Why cells respond differently to DNA damage: a chromatin perspective. Cell Cycle (Georgetown, Tex.). 7: 980-3. PMID 18414020 DOI: 10.4161/Cc.7.8.5646 |
0.579 |
|
| 2008 |
Toledo LI, Murga M, Gutierrez-Martinez P, Soria R, Fernandez-Capetillo O. ATR signaling can drive cells into senescence in the absence of DNA breaks. Genes & Development. 22: 297-302. PMID 18245444 DOI: 10.1101/Gad.452308 |
0.593 |
|
| 2007 |
Murga M, Jaco I, Fan Y, Soria R, Martinez-Pastor B, Cuadrado M, Yang SM, Blasco MA, Skoultchi AI, Fernandez-Capetillo O. Global chromatin compaction limits the strength of the DNA damage response. The Journal of Cell Biology. 178: 1101-8. PMID 17893239 DOI: 10.1083/Jcb.200704140 |
0.6 |
|
| 2007 |
Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, West SC, Donovan PJ, Nussenzweig A, Sharan SK. RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females. The Journal of Cell Biology. 176: 581-92. PMID 17312021 DOI: 10.1083/Jcb.200608130 |
0.725 |
|
| 2006 |
Cuadrado M, Martinez-Pastor B, Fernandez-Capetillo O. "ATR activation in response to ionizing radiation: still ATM territory". Cell Division. 1: 7. PMID 16759429 DOI: 10.1186/1747-1028-1-7 |
0.641 |
|
| 2006 |
Kruhlak MJ, Celeste A, Dellaire G, Fernandez-Capetillo O, Müller WG, McNally JG, Bazett-Jones DP, Nussenzweig A. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. The Journal of Cell Biology. 172: 823-34. PMID 16520385 DOI: 10.1083/Jcb.200510015 |
0.737 |
|
| 2006 |
Cuadrado M, Martinez-Pastor B, Murga M, Toledo LI, Gutierrez-Martinez P, Lopez E, Fernandez-Capetillo O. ATM regulates ATR chromatin loading in response to DNA double-strand breaks. The Journal of Experimental Medicine. 203: 297-303. PMID 16461339 DOI: 10.1084/Jem.20051923 |
0.566 |
|
| 2005 |
Difilippantonio S, Celeste A, Fernandez-Capetillo O, Chen HT, Reina San Martin B, Van Laethem F, Yang YP, Petukhova GV, Eckhaus M, Feigenbaum L, Manova K, Kruhlak M, Camerini-Otero RD, Sharan S, Nussenzweig M, et al. Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models. Nature Cell Biology. 7: 675-85. PMID 15965469 DOI: 10.1038/Ncb1270 |
0.692 |
|
| 2005 |
Lee AC, Fernandez-Capetillo O, Pisupati V, Jackson SP, Nussenzweig A. Specific association of mouse MDC1/NFBD1 with NBS1 at sites of DNA-damage. Cell Cycle (Georgetown, Tex.). 4: 177-82. PMID 15611643 DOI: 10.4161/Cc.4.1.1354 |
0.822 |
|
| 2005 |
Turner JM, Mahadevaiah SK, Fernandez-Capetillo O, Nussenzweig A, Xu X, Deng CX, Burgoyne PS. Silencing of unsynapsed meiotic chromosomes in the mouse. Nature Genetics. 37: 41-7. PMID 15580272 DOI: 10.1038/Ng1484 |
0.668 |
|
| 2004 |
Fernandez-Capetillo O, Lee A, Nussenzweig M, Nussenzweig A. H2AX: the histone guardian of the genome. Dna Repair. 3: 959-67. PMID 15279782 DOI: 10.1016/J.Dnarep.2004.03.024 |
0.819 |
|
| 2004 |
Fernandez-Capetillo O, Nussenzweig A. Aging counts on chromosomes. Nature Genetics. 36: 672-4. PMID 15226747 DOI: 10.1038/Ng0704-672 |
0.549 |
|
| 2004 |
Fernandez-Capetillo O, Allis CD, Nussenzweig A. Phosphorylation of histone H2B at DNA double-strand breaks Journal of Experimental Medicine. 199: 1671-1677. PMID 15197225 DOI: 10.1084/Jem.20032247 |
0.719 |
|
| 2004 |
Fernandez-Capetillo O, Nussenzweig A. Linking histone deacetylation with the repair of DNA breaks. Proceedings of the National Academy of Sciences of the United States of America. 101: 1427-8. PMID 14757822 DOI: 10.1073/Pnas.0307342101 |
0.744 |
|
| 2003 |
Fernandez-Capetillo O, Liebe B, Scherthan H, Nussenzweig A. H2AX regulates meiotic telomere clustering. The Journal of Cell Biology. 163: 15-20. PMID 14530383 DOI: 10.1083/Jcb.200305124 |
0.67 |
|
| 2003 |
Fernandez-Capetillo O, Celeste A, Nussenzweig A. Focusing on foci: H2AX and the recruitment of DNA-damage response factors. Cell Cycle (Georgetown, Tex.). 2: 426-7. PMID 12963833 DOI: 10.4161/Cc.2.5.509 |
0.699 |
|
| 2003 |
Celeste A, Difilippantonio S, Difilippantonio MJ, Fernandez-Capetillo O, Pilch DR, Sedelnikova OA, Eckhaus M, Ried T, Bonner WM, Nussenzweig A. H2AX haploinsufficiency modifies genomic stability and tumor susceptibility Cell. 114: 371-383. PMID 12914701 DOI: 10.1016/S0092-8674(03)00567-1 |
0.651 |
|
| 2003 |
Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, Bonner RF, Bonner WM, Nussenzweig A. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nature Cell Biology. 5: 675-9. PMID 12792649 DOI: 10.1038/Ncb1004 |
0.831 |
|
| 2003 |
Fernandez-Capetillo O, Mahadevaiah SK, Celeste A, Romanienko PJ, Camerini-Otero RD, Bonner WM, Manova K, Burgoyne P, Nussenzweig A. H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. Developmental Cell. 4: 497-508. PMID 12689589 DOI: 10.1016/S1534-5807(03)00093-5 |
0.594 |
|
| 2002 |
Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nature Cell Biology. 4: 993-7. PMID 12447390 DOI: 10.1038/Ncb884 |
0.728 |
|
| 2002 |
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, et al. Genomic instability in mice lacking histone H2AX. Science (New York, N.Y.). 296: 922-7. PMID 11934988 DOI: 10.1126/Science.1069398 |
0.75 |
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