Year |
Citation |
Score |
2024 |
Lin Z, Agarwal V, Cong Y, Pomponi SA, Schmidt EW. Short macrocyclic peptides in sponge genomes. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314383121. PMID 38442178 DOI: 10.1073/pnas.2314383121 |
0.309 |
|
2023 |
Li F, Lin Z, Krug PJ, Catrow JL, Cox JE, Schmidt EW. Animal FAS-like polyketide synthases produce diverse polypropionates. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305575120. PMID 37695909 DOI: 10.1073/pnas.2305575120 |
0.307 |
|
2022 |
Nguyen NA, Cong Y, Hurrell RC, Arias N, Garg N, Puri AW, Schmidt EW, Agarwal V. A Silent Biosynthetic Gene Cluster from a Methanotrophic Bacterium Potentiates Discovery of a Substrate Promiscuous Proteusin Cyclodehydratase. Acs Chemical Biology. PMID 35666841 DOI: 10.1021/acschembio.2c00251 |
0.36 |
|
2022 |
Li F, Lin Z, Torres JP, Hill EA, Li D, Townsend CA, Schmidt EW. Sea Urchin Polyketide Synthase SpPks1 Produces the Naphthalene Precursor to Echinoderm Pigments. Journal of the American Chemical Society. 144: 9363-9371. PMID 35588530 DOI: 10.1021/jacs.2c01416 |
0.713 |
|
2022 |
Zheng Y, Cong Y, Schmidt EW, Nair SK. Catalysts for the Enzymatic Lipidation of Peptides. Accounts of Chemical Research. PMID 35442036 DOI: 10.1021/acs.accounts.2c00108 |
0.31 |
|
2021 |
Nguyen NA, Lin Z, Mohanty I, Garg N, Schmidt EW, Agarwal V. An Obligate Peptidyl Brominase Underlies the Discovery of Highly Distributed Biosynthetic Gene Clusters in Marine Sponge Microbiomes. Journal of the American Chemical Society. PMID 34213321 DOI: 10.1021/jacs.1c03474 |
0.403 |
|
2021 |
Lin Z, Torres JP, Watkins M, Paguigan N, Niu C, Imperial JS, Tun J, Safavi-Hemami H, Finol-Urdaneta RK, Neves JLB, Espino S, Karthikeyan M, Olivera BM, Schmidt EW. Non-Peptidic Small Molecule Components from Cone Snail Venoms. Frontiers in Pharmacology. 12: 655981. PMID 34054536 DOI: 10.3389/fphar.2021.655981 |
0.313 |
|
2021 |
Morinaka BI, Schmidt EW, Purushothaman M, Sarkar S, Morita M, Gugger M. Genome mining based discovery of the cyclic peptide tolypamide and TolF, a Ser/Thr forward O-prenyltransferase. Angewandte Chemie (International Ed. in English). PMID 33586286 DOI: 10.1002/anie.202015975 |
0.355 |
|
2020 |
Sarkar S, Gu W, Schmidt EW. Expanding the chemical space of synthetic cyclic peptides using a promiscuous macrocyclase from prenylagaramide biosynthesis. Acs Catalysis. 10: 7146-7153. PMID 33457065 DOI: 10.1021/Acscatal.0C00623 |
0.463 |
|
2020 |
Montalbán-López M, Scott TA, Ramesh S, Rahman IR, van Heel AJ, Viel JH, Bandarian V, Dittmann E, Genilloud O, Goto Y, Grande Burgos MJ, Hill C, Kim S, Koehnke J, Latham JA, ... ... Schmidt EW, et al. New developments in RiPP discovery, enzymology and engineering. Natural Product Reports. PMID 32935693 DOI: 10.1039/D0Np00027B |
0.429 |
|
2020 |
Altamia MA, Lin Z, Trindade-Silva AE, Uy ID, Shipway JR, Wilke DV, Concepcion GP, Distel DL, Schmidt EW, Haygood MG. Secondary Metabolism in the Gill Microbiota of Shipworms (Teredinidae) as Revealed by Comparison of Metagenomes and Nearly Complete Symbiont Genomes. Msystems. 5. PMID 32606027 DOI: 10.1128/mSystems.00261-20 |
0.347 |
|
2020 |
Youssef DTA, Almagthali H, Shaala LA, Schmidt EW. Secondary Metabolites of the Genus : A Comprehensive Review of Chemical Diversity and Pharmacological Properties. Marine Drugs. 18. PMID 32545321 DOI: 10.3390/Md18060307 |
0.411 |
|
2020 |
Torres JP, Lin Z, Winter JM, Krug PJ, Schmidt EW. Animal biosynthesis of complex polyketides in a photosynthetic partnership. Nature Communications. 11: 2882. PMID 32513940 DOI: 10.1038/S41467-020-16376-5 |
0.39 |
|
2020 |
Larson EC, Lim AL, Pond CD, Craft M, Čavužić M, Waldrop GL, Schmidt EW, Barrows LR. Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase. Plos One. 15: e0233485. PMID 32470050 DOI: 10.1371/Journal.Pone.0233485 |
0.352 |
|
2020 |
Thapa HR, Lin Z, Yi D, Smith JE, Schmidt EW, Agarwal V. Genetic and biochemical reconstitution of bromoform biosynthesis in Asparagopsis lends insights into seaweed ROS enzymology. Acs Chemical Biology. PMID 32453942 DOI: 10.1021/Acschembio.0C00299 |
0.408 |
|
2020 |
O'Connor RM, Nepveux V FJ, Abenoja J, Bowden G, Reis P, Beaushaw J, Bone Relat RM, Driskell I, Gimenez F, Riggs MW, Schaefer DA, Schmidt EW, Lin Z, Distel DL, Clardy J, et al. A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity. Plos Pathogens. 16: e1008600. PMID 32453775 DOI: 10.1371/Journal.Ppat.1008600 |
0.336 |
|
2020 |
Torres JP, Lin Z, Fenton DS, Leavitt LU, Niu C, Lam PY, Robes JM, Peterson RT, Concepcion GP, Haygood MG, Olivera BM, Schmidt EW. Boholamide A, an APD-Class, Hypoxia-Selective Cyclodepsipeptide. Journal of Natural Products. PMID 32186874 DOI: 10.1021/Acs.Jnatprod.0C00038 |
0.373 |
|
2020 |
Miller BW, Torres JP, Tun JO, Flores MS, Forteza I, Rosenberg G, Haygood MG, Schmidt EW, Concepcion GP. Synergistic anti-methicillin-resistant Staphylococcus aureus (MRSA) activity and absolute stereochemistry of 7,8-dideoxygriseorhodin C. The Journal of Antibiotics. PMID 31992865 DOI: 10.1038/S41429-019-0275-8 |
0.315 |
|
2019 |
Torres JP, Schmidt EW. The biosynthetic diversity of the animal world. The Journal of Biological Chemistry. PMID 31604818 DOI: 10.1074/Jbc.Rev119.006130 |
0.452 |
|
2019 |
Lin Z, Kakule TB, Reilly CA, Beyhan S, Schmidt EW. Secondary Metabolites of Onygenales Fungi Exemplified by Aioliomyces pyridodomos. Journal of Natural Products. PMID 31155876 DOI: 10.1021/Acs.Jnatprod.9B00121 |
0.418 |
|
2018 |
Lin Z, Phadke S, Lu Z, Beyhan S, Abdel Aziz MH, Reilly C, Schmidt EW. Onydecalins, Fungal Polyketides with Anti- Histoplasma and Anti-TRP Activity. Journal of Natural Products. PMID 30507122 DOI: 10.1021/Acs.Jnatprod.7B01067 |
0.36 |
|
2018 |
Gu W, Sardar D, Pierce E, Schmidt EW. Roads to Rome: Role of Multiple Cassettes in Cyanobactin RiPP Biosynthesis. Journal of the American Chemical Society. PMID 30387998 DOI: 10.1021/Jacs.8B09328 |
0.454 |
|
2018 |
Wozniak CE, Lin Z, Schmidt EW, Hughes KT, Liou TG. Thailandamide: a fatty acid synthesis antibiotic that is co-expressed with a resistant target gene. Antimicrobial Agents and Chemotherapy. PMID 29914944 DOI: 10.1128/Aac.00463-18 |
0.347 |
|
2018 |
Gu W, Dong SH, Sarkar S, Nair SK, Schmidt EW. The Biochemistry and Structural Biology of Cyanobactin Pathways: Enabling Combinatorial Biosynthesis. Methods in Enzymology. 604: 113-163. PMID 29779651 DOI: 10.1016/Bs.Mie.2018.03.002 |
0.431 |
|
2018 |
Morita M, Hao Y, Jokela J, Sardar D, Lin Z, Sivonen K, Nair SK, Schmidt EW. Posttranslational Tyrosine Geranylation in Cyanobactin Biosynthesis. Journal of the American Chemical Society. PMID 29701961 DOI: 10.1021/Jacs.8B03137 |
0.432 |
|
2018 |
Morita M, Schmidt EW. Parallel lives of symbionts and hosts: chemical mutualism in marine animals. Natural Product Reports. 35: 357-378. PMID 29441375 DOI: 10.1039/C7Np00053G |
0.405 |
|
2018 |
Smith TE, Pond CD, Pierce E, Harmer ZP, Kwan J, Zachariah MM, Harper MK, Wyche TP, Matainaho TK, Bugni TS, Barrows LR, Ireland CM, Schmidt EW. Accessing chemical diversity from the uncultivated symbionts of small marine animals. Nature Chemical Biology. PMID 29291350 DOI: 10.1038/Nchembio.2537 |
0.744 |
|
2018 |
Estrada P, Morita M, Hao Y, Schmidt EW, Nair SK. A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases Journal of the American Chemical Society. 140: 8124-8127. DOI: 10.2210/Pdb6Pgm/Pdb |
0.34 |
|
2017 |
Torres JP, Tianero MD, Robes JMD, Kwan JC, Biggs JS, Concepcion GP, Olivera BM, Haygood MG, Schmidt EW. Stenotrophomonas-like bacteria are widespread symbionts in cone snail venom ducts. Applied and Environmental Microbiology. PMID 28986377 DOI: 10.1128/Aem.01418-17 |
0.727 |
|
2017 |
Gu W, Schmidt EW. Three Principles of Diversity-Generating Biosynthesis. Accounts of Chemical Research. PMID 28891639 DOI: 10.1021/Acs.Accounts.7B00330 |
0.511 |
|
2017 |
Olivera BM, Raghuraman S, Schmidt EW, Safavi-Hemami H. Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. PMID 28551870 DOI: 10.1007/S00359-017-1183-7 |
0.443 |
|
2017 |
Distel DL, Altamia MA, Lin Z, Shipway JR, Han A, Forteza I, Antemano R, Limbaco MGJP, Tebo AG, Dechavez R, Albano J, Rosenberg G, Concepcion GP, Schmidt EW, Haygood MG. Discovery of chemoautotrophic symbiosis in the giant shipworm Kuphus polythalamia (Bivalvia: Teredinidae) extends wooden-steps theory. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416684 DOI: 10.1073/Pnas.1620470114 |
0.313 |
|
2017 |
Agarwal V, Blanton JM, Podell S, Taton A, Schorn MA, Busch J, Lin Z, Schmidt EW, Jensen PR, Paul VJ, Biggs JS, Golden JW, Allen EE, Moore BS. Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges. Nature Chemical Biology. PMID 28319100 DOI: 10.1038/Nchembio.2330 |
0.411 |
|
2017 |
Sardar D, Hao Y, Lin Z, Morita M, Nair SK, Schmidt EW. Enzymatic N- and C-protection in cyanobactin RiPP natural products. Journal of the American Chemical Society. PMID 28195477 DOI: 10.1021/Jacs.6B12872 |
0.446 |
|
2017 |
Zhang S, Qiu Y, Kakule TB, Lu Z, Xu F, Lamb JG, Reilly CA, Zheng Y, Sham SW, Wang W, Xuan L, Schmidt EW, Zhan J. Identification of Cyclic Depsipeptides and Their Dedicated Synthetase from Hapsidospora irregularis. Journal of Natural Products. PMID 28106998 DOI: 10.1021/Acs.Jnatprod.6B00808 |
0.317 |
|
2017 |
Aihara K, Inokuma T, Jichu T, Lin Z, Fu F, Yamaoka K, Shigenaga A, Hutchins DA, Schmidt EW, Otaka A. Cysteine-Free Intramolecular Ligation of N-Sulfanylethylanilide Peptide Using 4-Mercaptobenzylphosphonic Acid: Synthesis of Cyclic Peptide Trichamide Synlett. 28: 1944-1949. DOI: 10.1055/S-0036-1589055 |
0.366 |
|
2016 |
Hao Y, Pierce E, Roe D, Morita M, McIntosh JA, Agarwal V, Cheatham TE, Schmidt EW, Nair SK. Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872314 DOI: 10.1073/Pnas.1609869113 |
0.399 |
|
2016 |
Sardar D, Tianero MD, Schmidt EW. Directing Biosynthesis: Practical Supply of Natural and Unnatural Cyanobactins. Methods in Enzymology. 575: 1-20. PMID 27417922 DOI: 10.1016/Bs.Mie.2016.02.012 |
0.46 |
|
2016 |
Lin Z, Torres JP, Tianero MD, Kwan JC, Schmidt EW. Origin of chemical diversity in the Prochloron-tunicate symbiosis. Applied and Environmental Microbiology. PMID 27037119 DOI: 10.1128/AEM.00860-16 |
0.654 |
|
2016 |
Tianero MD, Pierce E, Raghuraman S, Sardar D, McIntosh JA, Heemstra JR, Schonrock Z, Covington BC, Maschek JA, Cox JE, Bachmann BO, Olivera BM, Ruffner DE, Schmidt EW. Metabolic model for diversity-generating biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831074 DOI: 10.1073/Pnas.1525438113 |
0.631 |
|
2016 |
Sardar D, Schmidt EW. Combinatorial biosynthesis of RiPPs: docking with marine life. Current Opinion in Chemical Biology. 31: 15-21. PMID 26709871 DOI: 10.1016/J.Cbpa.2015.11.016 |
0.466 |
|
2015 |
Neves JL, Lin Z, Imperial JS, Antunes A, Vasconcelos V, Olivera BM, Schmidt EW. Small Molecules in the Cone Snail Arsenal. Organic Letters. PMID 26421741 DOI: 10.1021/Acs.Orglett.5B02389 |
0.349 |
|
2015 |
Sardar D, Lin Z, Schmidt EW. Modularity of RiPP Enzymes Enables Designed Synthesis of Decorated Peptides. Chemistry & Biology. PMID 26165156 DOI: 10.1016/J.Chembiol.2015.06.014 |
0.427 |
|
2015 |
Schmidt EW. The secret to a successful relationship: lasting chemistry between ascidians and their symbiotic bacteria. Invertebrate Biology : a Quarterly Journal of the American Microscopical Society and the Division of Invertebrate Zoology/Asz. 134: 88-102. PMID 25937788 DOI: 10.1111/Ivb.12071 |
0.429 |
|
2015 |
Schmidt EW. Natural products: Hunting microbial metabolites. Nature Chemistry. 7: 375-6. PMID 25901811 DOI: 10.1038/Nchem.2252 |
0.42 |
|
2015 |
Kakule TB, Zhang S, Zhan J, Schmidt EW. Biosynthesis of the tetramic acids Sch210971 and Sch210972. Organic Letters. 17: 2295-7. PMID 25885659 DOI: 10.1021/Acs.Orglett.5B00715 |
0.375 |
|
2015 |
Teichert RW, Schmidt EW, Olivera BM. Constellation pharmacology: a new paradigm for drug discovery. Annual Review of Pharmacology and Toxicology. 55: 573-89. PMID 25562646 DOI: 10.1146/Annurev-Pharmtox-010814-124551 |
0.34 |
|
2015 |
Kakule TB, Jadulco RC, Koch M, Janso JE, Barrows LR, Schmidt EW. Native promoter strategy for high-yielding synthesis and engineering of fungal secondary metabolites. Acs Synthetic Biology. 4: 625-33. PMID 25226362 DOI: 10.1021/Sb500296P |
0.374 |
|
2015 |
Tianero MD, Kwan JC, Wyche TP, Presson AP, Koch M, Barrows LR, Bugni TS, Schmidt EW. Species specificity of symbiosis and secondary metabolism in ascidians. The Isme Journal. 9: 615-28. PMID 25171330 DOI: 10.1038/Ismej.2014.152 |
0.679 |
|
2015 |
Ruffner DE, Schmidt EW, Heemstra JR. Assessing the combinatorial potential of the RiPP cyanobactin tru pathway. Acs Synthetic Biology. 4: 482-92. PMID 25140729 DOI: 10.1021/Sb500267D |
0.409 |
|
2015 |
Sardar D, Pierce E, McIntosh JA, Schmidt EW. Recognition sequences and substrate evolution in cyanobactin biosynthesis. Acs Synthetic Biology. 4: 167-76. PMID 24625112 DOI: 10.1021/Sb500019B |
0.444 |
|
2015 |
Haygood M, Altamia M, Elshahawi S, Han A, Lin Z, Betcher M, O'Connor R, Sandy M, Trinidade-Silva A, Butler A, Schmidt E, Concepcion G, Distel D. Versatile bacterial symbionts of shipworms contribute to wood digestion, fix nitrogen and produce secondary metabolites Planta Medica. 81. DOI: 10.1055/S-0035-1556140 |
0.39 |
|
2014 |
Kakule TB, Lin Z, Schmidt EW. Combinatorialization of fungal polyketide synthase-peptide synthetase hybrid proteins. Journal of the American Chemical Society. 136: 17882-90. PMID 25436464 DOI: 10.1021/Ja511087P |
0.463 |
|
2014 |
Jadulco RC, Koch M, Kakule TB, Schmidt EW, Orendt A, He H, Janso JE, Carter GT, Larson EC, Pond C, Matainaho TK, Barrows LR. Isolation of pyrrolocins A-C: cis- and trans-decalin tetramic acid antibiotics from an endophytic fungal-derived pathway. Journal of Natural Products. 77: 2537-44. PMID 25351193 DOI: 10.1021/Np500617U |
0.383 |
|
2014 |
Lin Z, Koch M, Abdel Aziz MH, Galindo-Murillo R, Tianero MD, Cheatham TE, Barrows LR, Reilly CA, Schmidt EW. Oxazinin A, a pseudodimeric natural product of mixed biosynthetic origin from a filamentous fungus. Organic Letters. 16: 4774-7. PMID 25188821 DOI: 10.1021/Ol502227X |
0.347 |
|
2014 |
Kwan JC, Tianero MD, Donia MS, Wyche TP, Bugni TS, Schmidt EW. Host control of symbiont natural product chemistry in cryptic populations of the tunicate Lissoclinum patella. Plos One. 9: e95850. PMID 24788869 DOI: 10.1371/Journal.Pone.0095850 |
0.799 |
|
2014 |
Lin Z, Zachariah MM, Marett L, Hughen RW, Teichert RW, Concepcion GP, Haygood MG, Olivera BM, Light AR, Schmidt EW. Griseorhodins D-F, neuroactive intermediates and end products of post-PKS tailoring modification in Griseorhodin biosynthesis. Journal of Natural Products. 77: 1224-30. PMID 24786728 DOI: 10.1021/Np500155D |
0.356 |
|
2014 |
Lin Z, Koch M, Pond CD, Mabeza G, Seronay RA, Concepcion GP, Barrows LR, Olivera BM, Schmidt EW. Structure and activity of lobophorins from a turrid mollusk-associated Streptomyces sp. The Journal of Antibiotics. 67: 121-6. PMID 24220110 DOI: 10.1038/Ja.2013.115 |
0.331 |
|
2014 |
Adnani N, Ellis GA, Wyche TP, Bugni TS, Kwan JC, Schmidt EW. Emerging Trends for Stimulating the Discovery of Natural Products Natural Products Analysis: Instrumentation, Methods, and Applications. 115-161. DOI: 10.1002/9781118876015.ch5 |
0.627 |
|
2013 |
Kwan JC, Schmidt EW. Bacterial endosymbiosis in a chordate host: long-term co-evolution and conservation of secondary metabolism. Plos One. 8: e80822. PMID 24324632 DOI: 10.1371/Journal.Pone.0080822 |
0.68 |
|
2013 |
Lin Z, Marett L, Hughen RW, Flores M, Forteza I, Ammon MA, Concepcion GP, Espino S, Olivera BM, Rosenberg G, Haygood MG, Light AR, Schmidt EW. Neuroactive diol and acyloin metabolites from cone snail-associated bacteria. Bioorganic & Medicinal Chemistry Letters. 23: 4867-9. PMID 23880542 DOI: 10.1016/J.Bmcl.2013.06.088 |
0.331 |
|
2013 |
Kakule TB, Sardar D, Lin Z, Schmidt EW. Two related pyrrolidinedione synthetase loci in Fusarium heterosporum ATCC 74349 produce divergent metabolites. Acs Chemical Biology. 8: 1549-57. PMID 23614392 DOI: 10.1021/Cb400159F |
0.383 |
|
2013 |
McIntosh JA, Lin Z, Tianero MD, Schmidt EW. Aestuaramides, a natural library of cyanobactin cyclic peptides resulting from isoprene-derived Claisen rearrangements. Acs Chemical Biology. 8: 877-83. PMID 23411099 DOI: 10.1021/Cb300614C |
0.442 |
|
2013 |
Lin Z, Torres JP, Ammon MA, Marett L, Teichert RW, Reilly CA, Kwan JC, Hughen RW, Flores M, Tianero MD, Peraud O, Cox JE, Light AR, Villaraza AJ, Haygood MG, ... ... Schmidt EW, et al. A bacterial source for mollusk pyrone polyketides. Chemistry & Biology. 20: 73-81. PMID 23352141 DOI: 10.1016/J.Chembiol.2012.10.019 |
0.697 |
|
2013 |
Elshahawi SI, Trindade-Silva AE, Hanora A, Han AW, Flores MS, Vizzoni V, Schrago CG, Soares CA, Concepcion GP, Distel DL, Schmidt EW, Haygood MG. Boronated tartrolon antibiotic produced by symbiotic cellulose-degrading bacteria in shipworm gills. Proceedings of the National Academy of Sciences of the United States of America. 110: E295-304. PMID 23288898 DOI: 10.1073/Pnas.1213892110 |
0.408 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Schmidt EW, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F |
0.77 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Schmidt EW, et al. Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) Natural Product Reports. 30: 1568-1568. DOI: 10.1039/C3Np90040A |
0.646 |
|
2012 |
Schmidt EW. Decoding and recoding the ribosomal peptide universe. Chemistry & Biology. 19: 1501-2. PMID 23261594 DOI: 10.1016/J.Chembiol.2012.12.002 |
0.441 |
|
2012 |
Kwan JC, Donia MS, Han AW, Hirose E, Haygood MG, Schmidt EW. Genome streamlining and chemical defense in a coral reef symbiosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 20655-60. PMID 23185008 DOI: 10.1073/Pnas.1213820109 |
0.786 |
|
2012 |
Agarwal V, Pierce E, McIntosh J, Schmidt EW, Nair SK. Structures of cyanobactin maturation enzymes define a family of transamidating proteases. Chemistry & Biology. 19: 1411-22. PMID 23177196 DOI: 10.1016/J.Chembiol.2012.09.012 |
0.39 |
|
2012 |
Lin Z, Falkinham JO, Tawfik KA, Jeffs P, Bray B, Dubay G, Cox JE, Schmidt EW. Burkholdines from Burkholderia ambifaria: antifungal agents and possible virulence factors. Journal of Natural Products. 75: 1518-23. PMID 22988812 DOI: 10.1021/Np300108U |
0.347 |
|
2012 |
Hou Y, Tianero MD, Kwan JC, Wyche TP, Michel CR, Ellis GA, Vazquez-Rivera E, Braun DR, Rose WE, Schmidt EW, Bugni TS. Structure and biosynthesis of the antibiotic bottromycin D. Organic Letters. 14: 5050-3. PMID 22984777 DOI: 10.1021/Ol3022758 |
0.648 |
|
2012 |
Kwan JC, Schmidt EW. Cleaning up polyketide synthases Chemistry and Biology. 19: 309-311. PMID 22444584 DOI: 10.1016/J.Chembiol.2012.03.003 |
0.641 |
|
2012 |
Lin Z, Flores M, Forteza I, Henriksen NM, Concepcion GP, Rosenberg G, Haygood MG, Olivera BM, Light AR, Cheatham TE, Schmidt EW. Totopotensamides, polyketide-cyclic peptide hybrids from a mollusk-associated bacterium Streptomyces sp. Journal of Natural Products. 75: 644-9. PMID 22439622 DOI: 10.1021/Np200886X |
0.397 |
|
2012 |
Schmidt EW, Donia MS, McIntosh JA, Fricke WF, Ravel J. Origin and variation of tunicate secondary metabolites. Journal of Natural Products. 75: 295-304. PMID 22233390 DOI: 10.1021/Np200665K |
0.719 |
|
2012 |
Tianero MD, Donia MS, Young TS, Schultz PG, Schmidt EW. Ribosomal route to small-molecule diversity. Journal of the American Chemical Society. 134: 418-25. PMID 22107593 DOI: 10.1021/Ja208278K |
0.733 |
|
2011 |
Donia MS, Fricke WF, Partensky F, Cox J, Elshahawi SI, White JR, Phillippy AM, Schatz MC, Piel J, Haygood MG, Ravel J, Schmidt EW. Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis. Proceedings of the National Academy of Sciences of the United States of America. 108: E1423-32. PMID 22123943 DOI: 10.1073/Pnas.1111712108 |
0.727 |
|
2011 |
McIntosh JA, Donia MS, Nair SK, Schmidt EW. Enzymatic basis of ribosomal peptide prenylation in cyanobacteria. Journal of the American Chemical Society. 133: 13698-705. PMID 21766822 DOI: 10.1021/Ja205458H |
0.742 |
|
2011 |
Donia MS, Ruffner DE, Cao S, Schmidt EW. Accessing the hidden majority of marine natural products through metagenomics. Chembiochem : a European Journal of Chemical Biology. 12: 1230-6. PMID 21542088 DOI: 10.1002/Cbic.201000780 |
0.765 |
|
2011 |
Donia MS, Schmidt EW. Linking chemistry and genetics in the growing cyanobactin natural products family. Chemistry & Biology. 18: 508-19. PMID 21513887 DOI: 10.1016/J.Chembiol.2011.01.019 |
0.764 |
|
2011 |
Donia MS, Fricke WF, Ravel J, Schmidt EW. Variation in tropical reef symbiont metagenomes defined by secondary metabolism. Plos One. 6: e17897. PMID 21445351 DOI: 10.1371/Journal.Pone.0017897 |
0.731 |
|
2010 |
Schmidt EW, Donia MS. Life in cellulose houses: symbiotic bacterial biosynthesis of ascidian drugs and drug leads. Current Opinion in Biotechnology. 21: 827-33. PMID 21050742 DOI: 10.1016/J.Copbio.2010.10.006 |
0.709 |
|
2010 |
Lin Z, Antemano RR, Hughen RW, Tianero MD, Peraud O, Haygood MG, Concepcion GP, Olivera BM, Light A, Schmidt EW. Pulicatins A-E, neuroactive thiazoline metabolites from cone snail-associated bacteria. Journal of Natural Products. 73: 1922-6. PMID 21028889 DOI: 10.1021/Np100588C |
0.351 |
|
2010 |
McIntosh JA, Robertson CR, Agarwal V, Nair SK, Bulaj GW, Schmidt EW. Circular logic: nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst. Journal of the American Chemical Society. 132: 15499-501. PMID 20961047 DOI: 10.1021/Ja1067806 |
0.389 |
|
2010 |
Schmidt EW. The hidden diversity of ribosomal peptide natural products. Bmc Biology. 8: 83. PMID 20594290 DOI: 10.1186/1741-7007-8-83 |
0.499 |
|
2010 |
McIntosh JA, Schmidt EW. Marine molecular machines: heterocyclization in cyanobactin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 11: 1413-21. PMID 20540059 DOI: 10.1002/Cbic.201000196 |
0.454 |
|
2010 |
McIntosh JA, Donia MS, Schmidt EW. Insights into heterocyclization from two highly similar enzymes. Journal of the American Chemical Society. 132: 4089-91. PMID 20210311 DOI: 10.1021/Ja9107116 |
0.711 |
|
2010 |
SCHMIDT EW, FAULKNER DJ. ChemInform Abstract: Microsclerodermins C-E, Antifungal Cyclic Peptides from the Lithistid Marine Sponges Theonella sp. and Microscleroderma sp. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199826240 |
0.457 |
|
2009 |
Brady SF, Simmons L, Kim JH, Schmidt EW. Metagenomic approaches to natural products from free-living and symbiotic organisms. Natural Product Reports. 26: 1488-503. PMID 19844642 DOI: 10.1039/B817078A |
0.438 |
|
2009 |
Peraud O, Biggs JS, Hughen RW, Light AR, Concepcion GP, Olivera BM, Schmidt EW. Microhabitats within venomous cone snails contain diverse actinobacteria. Applied and Environmental Microbiology. 75: 6820-6. PMID 19749071 DOI: 10.1128/Aem.01238-09 |
0.435 |
|
2009 |
McIntosh JA, Donia MS, Schmidt EW. Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds. Natural Product Reports. 26: 537-59. PMID 19642421 DOI: 10.1039/B714132G |
0.756 |
|
2009 |
Yang JC, Madupu R, Durkin AS, Ekborg NA, Pedamallu CS, Hostetler JB, Radune D, Toms BS, Henrissat B, Coutinho PM, Schwarz S, Field L, Trindade-Silva AE, Soares CA, Elshahawi S, ... ... Schmidt EW, et al. The complete genome of Teredinibacter turnerae T7901: an intracellular endosymbiont of marine wood-boring bivalves (shipworms). Plos One. 4: e6085. PMID 19568419 DOI: 10.1371/Journal.Pone.0006085 |
0.348 |
|
2009 |
Schmidt EW, Donia MS. Chapter 23. Cyanobactin ribosomally synthesized peptides--a case of deep metagenome mining. Methods in Enzymology. 458: 575-96. PMID 19374999 DOI: 10.1016/S0076-6879(09)04823-X |
0.757 |
|
2009 |
Lee J, McIntosh J, Hathaway BJ, Schmidt EW. Using marine natural products to discover a protease that catalyzes peptide macrocyclization of diverse substrates. Journal of the American Chemical Society. 131: 2122-4. PMID 19166292 DOI: 10.1021/Ja8092168 |
0.436 |
|
2008 |
Schmidt EW. Trading molecules and tracking targets in symbiotic interactions. Nature Chemical Biology. 4: 466-73. PMID 18641627 DOI: 10.1038/Nchembio.101 |
0.376 |
|
2008 |
Donia MS, Ravel J, Schmidt EW. A global assembly line for cyanobactins. Nature Chemical Biology. 4: 341-3. PMID 18425112 DOI: 10.1038/Nchembio.84 |
0.717 |
|
2006 |
Donia MS, Hathaway BJ, Sudek S, Haygood MG, Rosovitz MJ, Ravel J, Schmidt EW. Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians. Nature Chemical Biology. 2: 729-35. PMID 17086177 DOI: 10.1038/Nchembio829 |
0.765 |
|
2006 |
Sudek S, Haygood MG, Youssef DT, Schmidt EW. Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence. Applied and Environmental Microbiology. 72: 4382-7. PMID 16751554 DOI: 10.1128/Aem.00380-06 |
0.426 |
|
2005 |
Schmidt EW. From chemical structure to environmental biosynthetic pathways: navigating marine invertebrate-bacteria associations. Trends in Biotechnology. 23: 437-40. PMID 16038996 DOI: 10.1016/J.Tibtech.2005.07.002 |
0.441 |
|
2005 |
Schmidt EW, Nelson JT, Rasko DA, Sudek S, Eisen JA, Haygood MG, Ravel J. Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella. Proceedings of the National Academy of Sciences of the United States of America. 102: 7315-20. PMID 15883371 DOI: 10.1073/Pnas.0501424102 |
0.462 |
|
2005 |
Sims JW, Fillmore JP, Warner DD, Schmidt EW. Equisetin biosynthesis in Fusarium heterosporum. Chemical Communications (Cambridge, England). 186-8. PMID 15724180 DOI: 10.1039/B413523G |
0.316 |
|
2004 |
Schmidt EW, Sudek S, Haygood MG. Genetic evidence supports secondary metabolic diversity in Prochloron spp., the cyanobacterial symbiont of a tropical ascidian. Journal of Natural Products. 67: 1341-5. PMID 15332852 DOI: 10.1021/Np049948N |
0.438 |
|
2004 |
Schmidt EW, Raventos-Suarez C, Bifano M, Menendez AT, Fairchild CR, Faulkner DJ. Scleritodermin A, a cytotoxic cyclic peptide from the lithistid sponge Scleritoderma nodosum. Journal of Natural Products. 67: 475-8. PMID 15043437 DOI: 10.1021/Np034035Z |
0.53 |
|
2004 |
Schmidt EW, Nelson JT, Fillmore JP. Synthesis of tyrosine derivatives for saframycin MX1 biosynthetic studies Tetrahedron Letters. 45: 3921-3924. DOI: 10.1016/J.Tetlet.2004.03.112 |
0.39 |
|
2001 |
Hitchman TS, Schmidt EW, Trail F, Rarick MD, Linz JE, Townsend CA. Hexanoate synthase, a specialized type I fatty acid synthase in aflatoxin B1 biosynthesis. Bioorganic Chemistry. 29: 293-307. PMID 16256699 DOI: 10.1006/Bioo.2001.1216 |
0.551 |
|
2000 |
Schmidt EW, Obraztsova AY, Davidson SK, Faulkner DJ, Haygood MG. Identification of the antifungal peptide-containing symbiont of the marine sponge Theonella swinhoei as a novel δ-proteobacterium, "Candidatus Entotheonella palauensis" Marine Biology. 136: 969-977. DOI: 10.1007/S002270000273 |
0.387 |
|
1998 |
Schmidt EW, Bewley CA, Faulkner DJ. Theopalauamide, a Bicyclic Glycopeptide from Filamentous Bacterial Symbionts of the Lithistid Sponge Theonella swinhoei from Palau and Mozambique Journal of Organic Chemistry. 63: 1254-1258. DOI: 10.1021/Jo9718455 |
0.578 |
|
1998 |
Schmidt EW, Faulkner DJ. Microsclerodermins C-E, antifungal cyclic peptides from the lithistid marine sponges Theonella sp. and Microscleroderma sp Tetrahedron. 54: 3043-3056. DOI: 10.1016/S0040-4020(98)00054-4 |
0.389 |
|
1997 |
Schmidt EW, Harper MK, Faulkner DJ. Mozamides A and B, cyclic peptides from a theonellid sponge from Mozambique Journal of Natural Products. 60: 779-782. DOI: 10.1021/Np970195X |
0.367 |
|
1995 |
Schmidt EW, Harper MK, Faulkner DJ. Makaluvamines H-M and damirone C from the pohnpeian sponge Zyzzya fuliginosa. Journal of Natural Products. 58: 1861-7. PMID 8691207 |
0.346 |
|
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