| Year |
Citation |
Score |
| 2022 |
Le TA, Chu VT, Lino AC, Schrezenmeier E, Kressler C, Hamo D, Rajewsky K, Dörner T, Dang VD. Efficient CRISPR-Cas9-mediated mutagenesis in primary human B cells for identifying plasma cell regulators. Molecular Therapy. Nucleic Acids. 30: 621-632. PMID 36514352 DOI: 10.1016/j.omtn.2022.11.016 |
0.339 |
|
| 2022 |
Hagen M, Chakraborty T, Olson WJ, Heitz M, Hermann-Kleiter N, Kimpel J, Jenewein B, Pertoll J, Labi V, Rajewsky K, Derudder E. miR-142 favors naïve B cell residence in peripheral lymph nodes. Frontiers in Immunology. 13: 847415. PMID 36439112 DOI: 10.3389/fimmu.2022.847415 |
0.37 |
|
| 2022 |
Schmid VK, Khadour A, Ahmed N, Brandl C, Nitschke L, Rajewsky K, Jumaa H, Hobeika E. B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia. Haematologica. PMID 35021605 DOI: 10.3324/haematol.2021.279924 |
0.369 |
|
| 2020 |
Schmidt K, Sack U, Graf R, Winkler W, Popp O, Mertins P, Sommermann T, Kocks C, Rajewsky K. B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS. Frontiers in Immunology. 11: 602868. PMID 33343574 DOI: 10.3389/fimmu.2020.602868 |
0.385 |
|
| 2020 |
Tran NT, Graf R, Wulf-Goldenberg A, Stecklum M, Strauß G, Kühn R, Kocks C, Rajewsky K, Chu VT. CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32822592 DOI: 10.1016/J.Ymthe.2020.08.004 |
0.342 |
|
| 2020 |
Sommermann T, Yasuda T, Ronen J, Wirtz T, Weber T, Sack U, Caeser R, Zhang J, Li X, Chu VT, Jauch A, Unger K, Hodson DJ, Akalin A, Rajewsky K. Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32522871 DOI: 10.1073/Pnas.1921139117 |
0.472 |
|
| 2020 |
Jumaa H, Caganova M, McAllister EJ, Hoenig L, He X, Saltukoglu D, Brenker K, Köhler M, Leben R, Hauser AE, Niesner R, Rajewsky K, Reth M, Jellusova J. Immunoglobulin expression in the endoplasmic reticulum shapes the metabolic fitness of B lymphocytes. Life Science Alliance. 3. PMID 32341085 DOI: 10.26508/lsa.202000700 |
0.353 |
|
| 2019 |
Labi V, Peng S, Klironomos F, Munschauer M, Kastelic N, Chakraborty T, Schoeler K, Derudder E, Martella M, Mastrobuoni G, Hernandez-Miranda LR, Lahmann I, Kocks C, Birchmeier C, Kempa S, ... ... Rajewsky K, et al. Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat. Genes & Development. PMID 31699777 DOI: 10.1101/Gad.330134.119 |
0.346 |
|
| 2019 |
Rajewsky K. The advent and rise of monoclonal antibodies. Nature. 575: 47-49. PMID 31686050 DOI: 10.1038/D41586-019-02840-W |
0.339 |
|
| 2019 |
Wong JB, Hewitt SL, Heltemes-Harris LM, Mandal M, Johnson K, Rajewsky K, Koralov SB, Clark MR, Farrar MA, Skok JA. B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage. Nature Communications. 10: 4768. PMID 31628339 DOI: 10.1038/S41467-019-12824-Z |
0.446 |
|
| 2019 |
Tran NT, Sommermann T, Graf R, Trombke J, Pempe J, Petsch K, Kühn R, Rajewsky K, Chu VT. Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells. Cell Reports. 28: 3510-3522.e5. PMID 31553918 DOI: 10.1016/J.Celrep.2019.08.065 |
0.415 |
|
| 2019 |
Le TTH, Tran NT, Dao TML, Nguyen DD, Do HD, Ha TL, Kühn R, Nguyen TL, Rajewsky K, Chu VT. Efficient and Precise CRISPR/Cas9-Mediated MECP2 Modifications in Human-Induced Pluripotent Stem Cells. Frontiers in Genetics. 10: 625. PMID 31333716 DOI: 10.3389/Fgene.2019.00625 |
0.355 |
|
| 2019 |
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A, Rajewsky K, Labi V. TET enzymes control antibody production and shape the mutational landscape in germinal center B cells. The Febs Journal. PMID 31120187 DOI: 10.1111/Febs.14934 |
0.517 |
|
| 2019 |
Tran NT, Bashir S, Li X, Rossius J, Chu VT, Rajewsky K, Kühn R. Enhancement of Precise Gene Editing by the Association of Cas9 With Homologous Recombination Factors. Frontiers in Genetics. 10: 365. PMID 31114605 DOI: 10.3389/Fgene.2019.00365 |
0.334 |
|
| 2019 |
Graf R, Seagal J, Otipoby KL, Lam KP, Ayoub S, Zhang B, Sander S, Chu VT, Rajewsky K. BCR-dependent lineage plasticity in mature B cells. Science (New York, N.Y.). 363: 748-753. PMID 30765568 DOI: 10.1126/Science.Aau8475 |
0.48 |
|
| 2019 |
Schoeler K, Mittermeier T, Villunger A, Rajewsky K, Labi V. Addiction of B Cell Lymphomas to microRNA-17-92 Is Mediated By a Single Target Gene Blood. 134: 1258-1258. DOI: 10.1182/Blood-2019-126483 |
0.44 |
|
| 2018 |
Benhamou D, Labi V, Getahun A, Benchetrit E, Dowery R, Rajewsky K, Cambier JC, Melamed D. The c-Myc/miR17-92/PTEN Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development. Frontiers in Immunology. 9: 2715. PMID 30524445 DOI: 10.3389/Fimmu.2018.02715 |
0.45 |
|
| 2018 |
Weber T, Seagal J, Winkler W, Wirtz T, Chu VT, Rajewsky K. A novel allele for inducible Cre expression in germinal center B cells. European Journal of Immunology. PMID 30359469 DOI: 10.1002/Eji.201847863 |
0.475 |
|
| 2018 |
Kabrani E, Chu VT, Tasouri E, Sommermann T, Baßler K, Ulas T, Zenz T, Bullinger L, Schultze J, Rajewsky K, Sander S. Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells. Blood. PMID 30333121 DOI: 10.1182/Blood-2018-06-856203 |
0.4 |
|
| 2018 |
Choi IK, Wang Z, Ke Q, Hong M, Qian Y, Zhao X, Liu Y, Kim HJ, Ritz J, Cantor H, Rajewsky K, Wucherpfennig KW, Zhang B. Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311309 DOI: 10.1073/Pnas.1713607115 |
0.396 |
|
| 2018 |
Casola S, Varano G, Perucho L, Ossorio M, Zanardi F, Sormani M, Petrocelli V, Zasada C, Kempa S, Rajewsky K, Ponzoni M, Facchetti F. Myc and the Warburg Effect Blood. 132: SCI-12-SCI-12. DOI: 10.1182/Blood-2018-99-109471 |
0.485 |
|
| 2017 |
Dobeš J, Edenhofer F, Vobořil M, Brabec T, Dobešová M, Čepková A, Klein L, Rajewsky K, Filipp D. A novel conditional Aire allele enables cell specific ablation of the immune tolerance regulator Aire. European Journal of Immunology. PMID 29193031 DOI: 10.1002/Eji.201747267 |
0.365 |
|
| 2017 |
Chu VT, Graf R, Rajewsky K. CRISPR/Cas9-Mediated In Vitro Mutagenesis in GC-Like B Cells. Methods in Molecular Biology (Clifton, N.J.). 1623: 135-145. PMID 28589354 DOI: 10.1007/978-1-4939-7095-7_12 |
0.504 |
|
| 2017 |
Varano G, Raffel S, Sormani M, Zanardi F, Lonardi S, Zasada C, Perucho L, Petrocelli V, Haake A, Lee AK, Bugatti M, Paul U, Van Anken E, Pasqualucci L, Rabadan R, ... ... Rajewsky K, et al. The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition. Nature. PMID 28562582 DOI: 10.1038/Nature22353 |
0.47 |
|
| 2017 |
Wanke F, Moos S, Croxford AL, Heinen AP, Gräf S, Kalt B, Tischner D, Zhang J, Christen I, Bruttger J, Yogev N, Tang Y, Zayoud M, Israel N, Karram K, ... ... Rajewsky K, et al. EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells. Cell Reports. 18: 1270-1284. PMID 28147280 DOI: 10.1016/J.Celrep.2017.01.020 |
0.377 |
|
| 2016 |
Coffre M, Benhamou D, Rieß D, Blumenberg L, Snetkova V, Hines MJ, Chakraborty T, Bajwa S, Jensen K, Chong MM, Getu L, Silverman GJ, Blelloch R, Littman DR, Calado D, ... ... Rajewsky K, et al. miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation. Cell Reports. 17: 2271-2285. PMID 27880903 DOI: 10.1016/J.Celrep.2016.11.006 |
0.615 |
|
| 2016 |
Wirtz T, Weber T, Kracker S, Sommermann T, Rajewsky K, Yasuda T. Mouse model for acute Epstein-Barr virus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 27856754 DOI: 10.1073/Pnas.1616574113 |
0.476 |
|
| 2016 |
Chu VT, Graf R, Wirtz T, Weber T, Favret J, Li X, Petsch K, Tran NT, Sieweke MH, Berek C, Kühn R, Rajewsky K. Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line. Proceedings of the National Academy of Sciences of the United States of America. PMID 27729526 DOI: 10.1073/Pnas.1613884113 |
0.47 |
|
| 2016 |
Benhamou D, Labi V, Novak R, Dai I, Shafir-Alon S, Weiss A, Gaujoux R, Arnold R, Shen-Orr SS, Rajewsky K, Melamed D. A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency. Cell Reports. PMID 27346348 DOI: 10.1016/J.Celrep.2016.05.084 |
0.431 |
|
| 2016 |
Xiao C, Calado DP, Galler G, Thai TH, Patterson HC, Wang J, Rajewsky N, Bender TP, Rajewsky K. MiR-150 Controls B Cell Differentiation by Targeting the Transcription Factor c-Myb. Cell. 165: 1027. PMID 27153500 DOI: 10.1016/J.Cell.2016.04.056 |
0.771 |
|
| 2016 |
Derudder E, Herzog S, Labi V, Yasuda T, Köchert K, Janz M, Villunger A, Schmidt-Supprian M, Rajewsky K. Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27099294 DOI: 10.1073/Pnas.1604529113 |
0.454 |
|
| 2016 |
Orlanski S, Labi V, Reizel Y, Spiro A, Lichtenstein M, Levin-Klein R, Koralov SB, Skversky Y, Rajewsky K, Cedar H, Bergman Y. Tissue-specific DNA demethylation is required for proper B-cell differentiation and function. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091986 DOI: 10.1073/Pnas.1604365113 |
0.453 |
|
| 2016 |
Levit-Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity PC, Rajewsky K, Reth M, Hobeika E. Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26843325 DOI: 10.4049/Jimmunol.1501707 |
0.499 |
|
| 2016 |
Cho S, Wu CJ, Yasuda T, Cruz LO, Khan AA, Lin LL, Nguyen DT, Miller M, Lee HM, Kuo ML, Broide DH, Rajewsky K, Rudensky AY, Lu LF. miR-23∼27∼24 clusters control effector T cell differentiation and function. The Journal of Experimental Medicine. PMID 26834155 DOI: 10.1084/Jem.20150990 |
0.304 |
|
| 2016 |
Farber DL, Netea MG, Radbruch A, Rajewsky K, Zinkernagel RM. Immunological memory: lessons from the past and a look to the future. Nature Reviews. Immunology. 16: 124-8. PMID 26831526 DOI: 10.1038/Nri.2016.13 |
0.433 |
|
| 2016 |
Chu VT, Weber T, Graf R, Sommermann T, Petsch K, Sack U, Volchkov P, Rajewsky K, Kühn R. Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes. Bmc Biotechnology. 16: 4. PMID 26772810 DOI: 10.1186/S12896-016-0234-4 |
0.715 |
|
| 2015 |
Sander S, Chu VT, Yasuda T, Franklin A, Graf R, Calado DP, Li S, Imami K, Selbach M, Di Virgilio M, Bullinger L, Rajewsky K. PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones. Immunity. PMID 26620760 DOI: 10.1016/J.Immuni.2015.10.021 |
0.422 |
|
| 2015 |
Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, Browning JL, Goossens N, Nakagawa S, Gunasekaran G, Schwartz ME, Kobayashi M, Kumada H, Berger M, Pappo O, ... Rajewsky K, et al. Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. Nature Immunology. PMID 26502405 DOI: 10.1038/Ni.3290 |
0.317 |
|
| 2015 |
Akilli Öztürk Ö, Pakula H, Chmielowiec J, Qi J, Stein S, Lan L, Sasaki Y, Rajewsky K, Birchmeier W. Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence. Cell Reports. 13: 561-72. PMID 26456821 DOI: 10.1016/J.Celrep.2015.09.015 |
0.332 |
|
| 2015 |
Otipoby KL, Waisman A, Derudder E, Srinivasan L, Franklin A, Rajewsky K. The B-cell antigen receptor integrates adaptive and innate immune signals. Proceedings of the National Academy of Sciences of the United States of America. 112: 12145-50. PMID 26371314 DOI: 10.1073/Pnas.1516428112 |
0.428 |
|
| 2015 |
Ba Z, Meng FL, Gostissa M, Huang PY, Ke Q, Wang Z, Dao MN, Fujiwara Y, Rajewsky K, Zhang B, Alt FW. A Rapid Embryonic Stem Cell-Based Mouse Model for B-cell Lymphomas Driven by Epstein-Barr Virus Protein LMP1. Cancer Immunology Research. 3: 641-9. PMID 25934172 DOI: 10.1158/2326-6066.Cir-15-0058 |
0.51 |
|
| 2015 |
Zhang B, Calado DP, Wang Z, Fröhler S, Köchert K, Qian Y, Koralov SB, Schmidt-Supprian M, Sasaki Y, Unitt C, Rodig S, Chen W, Dalla-Favera R, Alt FW, Pasqualucci L, ... Rajewsky K, et al. An oncogenic role for alternative NF-κB signaling in DLBCL revealed upon deregulated BCL6 expression. Cell Reports. 11: 715-26. PMID 25921526 DOI: 10.1016/J.Celrep.2015.03.059 |
0.331 |
|
| 2015 |
Rajewsky K. The Herzenberg lecture: how to make a B-1 cell? Annals of the New York Academy of Sciences. PMID 25912787 DOI: 10.1111/Nyas.12767 |
0.441 |
|
| 2015 |
Chu VT, Weber T, Wefers B, Wurst W, Sander S, Rajewsky K, Kühn R. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nature Biotechnology. 33: 543-8. PMID 25803306 DOI: 10.1038/Nbt.3198 |
0.342 |
|
| 2015 |
Rajewsky K. The DNA deamination model of somatic antibody diversification Journal of Immunology. 194: 2041-2042. PMID 25710956 DOI: 10.4049/Jimmunol.1403252 |
0.414 |
|
| 2015 |
Sun A, Novobrantseva TI, Coffre M, Hewitt SL, Jensen K, Skok JA, Rajewsky K, Koralov SB. VH replacement in primary immunoglobulin repertoire diversification. Proceedings of the National Academy of Sciences of the United States of America. 112: E458-66. PMID 25609670 DOI: 10.1073/Pnas.1418001112 |
0.42 |
|
| 2015 |
Rajewsky K. The Herzenberg lecture: How to make a B-1 cell? Annals of the New York Academy of Sciences. DOI: 10.1111/nyas.12767 |
0.339 |
|
| 2014 |
Kreher S, Bouhlel MA, Cauchy P, Lamprecht B, Li S, Grau M, Hummel F, Köchert K, Anagnostopoulos I, Jöhrens K, Hummel M, Hiscott J, Wenzel SS, Lenz P, Schneider M, ... ... Rajewsky K, et al. Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 111: E4513-22. PMID 25288773 DOI: 10.1073/Pnas.1406985111 |
0.392 |
|
| 2014 |
Backert I, Koralov SB, Wirtz S, Kitowski V, Billmeier U, Martini E, Hofmann K, Hildner K, Wittkopf N, Brecht K, Waldner M, Rajewsky K, Neurath MF, Becker C, Neufert C. STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis. Journal of Immunology (Baltimore, Md. : 1950). 193: 3779-91. PMID 25187663 DOI: 10.4049/Jimmunol.1303076 |
0.354 |
|
| 2014 |
Hojer C, Frankenberger S, Strobl LJ, Feicht S, Djermanovic K, Jagdhuber F, Hömig-Hölzel C, Ferch U, Ruland J, Rajewsky K, Zimber-Strobl U. B-cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19. Cancer Research. 74: 4318-28. PMID 24938766 DOI: 10.1158/0008-5472.Can-13-3274 |
0.349 |
|
| 2014 |
Takemori T, Kaji T, Takahashi Y, Shimoda M, Rajewsky K. Generation of memory B cells inside and outside germinal centers European Journal of Immunology. 44: 1258-1264. PMID 24610726 DOI: 10.1002/Eji.201343716 |
0.641 |
|
| 2014 |
Heuberger J, Kosel F, Qi J, Grossmann KS, Rajewsky K, Birchmeier W. Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine Proceedings of the National Academy of Sciences of the United States of America. 111: 3472-3477. PMID 24550486 DOI: 10.1073/Pnas.1309342111 |
0.377 |
|
| 2014 |
Colombo E, Tentorio P, Musio S, Rajewsky K, Pedotti R, Casola S, Farina C. Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity. Clinical and Experimental Immunology. 176: 58-65. PMID 24325711 DOI: 10.1111/Cei.12250 |
0.49 |
|
| 2013 |
Yasuda T, Wirtz T, Zhang B, Wunderlich T, Schmidt-Supprian M, Sommermann T, Rajewsky K. Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice Cold Spring Harbor Symposia On Quantitative Biology. 78: 259-263. PMID 24241423 DOI: 10.1101/Sqb.2013.78.020222 |
0.387 |
|
| 2013 |
Kreslavsky T, Kim HJ, Koralov SB, Ghitza D, Buch T, Cantor H, Rajewsky K, Von Boehmer H. Negative selection, not receptor editing, is a physiological response of autoreactive thymocytes Journal of Experimental Medicine. 210: 1911-1918. PMID 23980099 DOI: 10.1084/Jem.20130876 |
0.42 |
|
| 2013 |
Jin HY, Oda H, Lai M, Skalsky RL, Bethel K, Shepherd J, Kang SG, Liu WH, Sabouri-Ghomi M, Cullen BR, Rajewsky K, Xiao C. MicroRNA-17∼92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways Embo Journal. 32: 2377-2391. PMID 23921550 DOI: 10.1038/Emboj.2013.178 |
0.319 |
|
| 2013 |
Gu H, Zou YR, Rajewsky K. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Journal of Immunology (Baltimore, Md. : 1950). 191: 7-16. PMID 23794701 DOI: 10.1016/0092-8674(93)90644-6 |
0.336 |
|
| 2013 |
Wang D, Höing S, Patterson HC, Ahmad UM, Rathinam VA, Rajewsky K, Fitzgerald KA, Golenbock DT. Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins. The Journal of Biological Chemistry. 288: 4594-601. PMID 23293022 DOI: 10.1074/Jbc.M112.443077 |
0.777 |
|
| 2013 |
Rajewsky K. Years in cologne Annual Review of Immunology. 31: 1-29. PMID 23140542 DOI: 10.1146/Annurev.Immunol.021908.132646 |
0.445 |
|
| 2012 |
Sander S, Rajewsky K. Burkitt lymphomagenesis linked to MYC plus PI3K in germinal center B cells Oncotarget. 3: 1066-1067. PMID 23164662 DOI: 10.18632/Oncotarget.726 |
0.356 |
|
| 2012 |
Kaji T, Ishige A, Hikida M, Taka J, Hijikata A, Kubo M, Nagashima T, Takahashi Y, Kurosaki T, Okada M, Ohara O, Rajewsky K, Takemori T. Distinct cellular pathways select germlineencoded and somatically mutated antibodies into immunological memory Journal of Experimental Medicine. 209: 2079-2097. PMID 23027924 DOI: 10.1084/Jem.20120127 |
0.675 |
|
| 2012 |
Calado DP, Sasaki Y, Godinho SA, Pellerin A, Köchert K, Sleckman BP, De Alborán IM, Janz M, Rodig S, Rajewsky K. The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers Nature Immunology. 13: 1092-1100. PMID 23001146 DOI: 10.1038/Ni.2418 |
0.448 |
|
| 2012 |
Sander S, Calado DP, Srinivasan L, Köchert K, Zhang B, Rosolowski M, Rodig SJ, Holzmann K, Stilgenbauer S, Siebert R, Bullinger L, Rajewsky K. Synergy between PI3K Signaling and MYC in Burkitt Lymphomagenesis Cancer Cell. 22: 167-179. PMID 22897848 DOI: 10.1016/J.Ccr.2012.06.012 |
0.388 |
|
| 2012 |
Zhang B, Kracker S, Yasuda T, Casola S, Vanneman M, Hömig-Hölzel C, Wang Z, Derudder E, Li S, Chakraborty T, Cotter SE, Koyama S, Currie T, Freeman GJ, Kutok JL, ... ... Rajewsky K, et al. Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model. Cell. 148: 739-51. PMID 22341446 DOI: 10.1016/J.Cell.2011.12.031 |
0.447 |
|
| 2012 |
Dagan LN, Jiang X, Bhatt S, Cubedo E, Rajewsky K, Lossos IS. miR-155 regulates HGAL expression and increases lymphoma cell motility Blood. 119: 513-520. PMID 22096245 DOI: 10.1182/Blood-2011-08-370536 |
0.391 |
|
| 2012 |
Goel S, Fogli LK, Sundrud M, Casola S, Rajewsky K, Koralov SB. Role of STAT3 and Th17 Cells in Cutaneous T Cell Lymphoma Blood. 120: 66-66. DOI: 10.1182/Blood.V120.21.66.66 |
0.419 |
|
| 2011 |
McCulloch L, Brown KL, Bradford BM, Hopkins J, Bailey M, Rajewsky K, Manson JC, Mabbott NA. Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen. Plos Pathogens. 7: e1002402. PMID 22144895 DOI: 10.1371/Journal.Ppat.1002402 |
0.332 |
|
| 2011 |
Wesemann DR, Magee JM, Boboila C, Calado DP, Gallagher MP, Portuguese AJ, Manis JP, Zhou X, Recher M, Rajewsky K, Notarangelo LD, Alt FW. Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination. The Journal of Experimental Medicine. 208: 2733-46. PMID 22143888 DOI: 10.1084/Jem.20111155 |
0.367 |
|
| 2011 |
Ko M, Bandukwala HS, An J, Lamperti ED, Thompson EC, Hastie R, Tsangaratou A, Rajewsky K, Koralov SB, Rao A. Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 14566-71. PMID 21873190 DOI: 10.1073/Pnas.1112317108 |
0.37 |
|
| 2011 |
Patterson HC, Kraus M, Wang D, Shahsafaei A, Henderson JM, Seagal J, Otipoby KL, Thai TH, Rajewsky K. Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation. Journal of Immunology (Baltimore, Md. : 1950). 187: 2853-8. PMID 21841126 DOI: 10.4049/Jimmunol.1101143 |
0.792 |
|
| 2011 |
Kometani K, Yamada T, Sasaki Y, Yokosuka T, Saito T, Rajewsky K, Ishiai M, Hikida M, Kurosaki T. CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway Journal of Experimental Medicine. 208: 1447-1457. PMID 21708930 DOI: 10.1084/Jem.20102665 |
0.473 |
|
| 2011 |
Vlantis K, Wullaert A, Sasaki Y, Schmidt-Supprian M, Rajewsky K, Roskams T, Pasparakis M. Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice Journal of Clinical Investigation. 121: 2781-2793. PMID 21701067 DOI: 10.1172/Jci45349 |
0.351 |
|
| 2011 |
Eschbach C, Bach MP, Fidler I, Pelanda R, Köhler F, Rajewsky K, Jumaa H. Efficient generation of B lymphocytes by recognition of self-antigens. European Journal of Immunology. 41: 2397-403. PMID 21604259 DOI: 10.1002/Eji.201041344 |
0.488 |
|
| 2011 |
Green MR, Monti S, Dalla-Favera R, Pasqualucci L, Walsh NC, Schmidt-Supprian M, Kutok JL, Rodig SJ, Neuberg DS, Rajewsky K, Golub TR, Alt FW, Shipp MA, Manis JP. Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program. Proceedings of the National Academy of Sciences of the United States of America. 108: 2873-8. PMID 21282644 DOI: 10.1073/Pnas.1019537108 |
0.471 |
|
| 2011 |
Ko M, Bandukwala HS, An J, Lamperti ED, Thompson EC, Hastie R, Tsangaratou A, Rajewsky K, Koralov SB, Rao A. Tet2 Negatively Regulates Homeostasis and Differentiation of Hematopoietic Stem Cells in Mice Blood. 118: 2354-2354. DOI: 10.1182/Blood.V118.21.2354.2354 |
0.384 |
|
| 2010 |
Calado DP, Zhang B, Srinivasan L, Sasaki Y, Seagal J, Unitt C, Rodig S, Kutok J, Tarakhovsky A, Schmidt-Supprian M, Rajewsky K. Constitutive Canonical NF-κB Activation Cooperates with Disruption of BLIMP1 in the Pathogenesis of Activated B Cell-like Diffuse Large Cell Lymphoma Cancer Cell. 18: 580-589. PMID 21156282 DOI: 10.1016/J.Ccr.2010.11.024 |
0.414 |
|
| 2010 |
Mandelbaum J, Bhagat G, Tang H, Mo T, Brahmachary M, Shen Q, Chadburn A, Rajewsky K, Tarakhovsky A, Pasqualucci L, Dalla-Favera R. BLIMP1 Is a Tumor Suppressor Gene Frequently Disrupted in Activated B Cell-like Diffuse Large B Cell Lymphoma Cancer Cell. 18: 568-579. PMID 21156281 DOI: 10.1016/J.Ccr.2010.10.030 |
0.471 |
|
| 2010 |
Espinosa L, Cathelin S, D'Altri T, Trimarchi T, Statnikov A, Guiu J, Rodilla V, Inglés-Esteve J, Nomdedeu J, Bellosillo B, Besses C, Abdel-Wahab O, Kucine N, Sun SC, Song G, ... ... Rajewsky K, et al. The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia Cancer Cell. 18: 268-281. PMID 20832754 DOI: 10.1016/J.Ccr.2010.08.006 |
0.371 |
|
| 2010 |
Ghosh S, Koralov SB, Stevanovic I, Sundrud MS, Sasaki Y, Rajewsky K, Rao A, Müller MR. Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America. 107: 15169-15174. PMID 20696888 DOI: 10.1073/Pnas.1009193107 |
0.376 |
|
| 2010 |
Kitamura D, Kudo A, Schaal S, Müller W, Melchers F, Rajewsky K. Pillars article: a critical role of lambda 5 protein in B cell development. Cell. 1992. 69: 823-831. Journal of Immunology (Baltimore, Md. : 1950). 184: 1130-8. PMID 20089708 |
0.307 |
|
| 2010 |
Nishimura M, Hara Y, Murakami A, Azuma T, Inamine A, Sakamoto A, Yoshida N, Arima M, Ikari J, Hatano M, Okamoto Y, Tokuhisa T, Nojima T, Haniuda K, Moutai T, ... ... Rajewsky K, et al. B cell memory (WS-081) Chairpersons: Masaki Hikida, David Tarlinton International Immunology. 22. DOI: 10.1093/Intimm/Dxq332 |
0.362 |
|
| 2010 |
Rajewsky K, Srinivasan L, Sasaki Y, Otipoby K, Waisman A, Zhang B, Kracker S, Yasuda T, Casola S. B-cell maintenance, response and surveillance (ML11) International Immunology. 22: iv1-iv1. DOI: 10.1093/Intimm/Dxq220 |
0.408 |
|
| 2009 |
Srinivasan L, Sasaki Y, Calado DP, Zhang B, Paik JH, DePinho RA, Kutok JL, Kearney JF, Otipoby KL, Rajewsky K. PI3 kinase signals BCR-dependent mature B cell survival. Cell. 139: 573-86. PMID 19879843 DOI: 10.1016/J.Cell.2009.08.041 |
0.401 |
|
| 2009 |
Lienenklaus S, Cornitescu M, Ziȩtara N, Łyszkiewicz M, Gekara N, Jabłońska J, Edenhofer F, Rajewsky K, Bruder D, Hafner M, Staeheli P, Weiss S. Novel reporter mouse reveals constitutive and inflammatory expression of IFN-β in vivo Journal of Immunology. 183: 3229-3236. PMID 19667093 DOI: 10.4049/Jimmunol.0804277 |
0.312 |
|
| 2009 |
Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW. Mechanisms promoting translocations in editing and switching peripheral B cells. Nature. 460: 231-6. PMID 19587764 DOI: 10.1038/Nature08159 |
0.449 |
|
| 2009 |
Derudder E, Cadera EJ, Vahl JC, Wang J, Fox CJ, Zha S, van Loo G, Pasparakis M, Schlissel MS, Schmidt-Supprian M, Rajewsky K. Development of immunoglobulin λ-chain-positive B cells, but not editing of immunoglobulin κ-chain, depends on NF-κB signals Nature Immunology. 10: 647-654. PMID 19412180 DOI: 10.1038/Ni.1732 |
0.412 |
|
| 2009 |
Müller MR, Sasaki Y, Stevanovic I, Lamperti ED, Ghosh S, Sharma S, Gelinas C, Rossi DJ, Pipkin ME, Rajewsky K, Hogan PG, Rao A. Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development. Proceedings of the National Academy of Sciences of the United States of America. 106: 7034-9. PMID 19351896 DOI: 10.1073/Pnas.0813296106 |
0.66 |
|
| 2009 |
Hikida M, Casola S, Takahashi N, Kaji T, Takemori T, Rajewsky K, Kurosaki T. PLC-γ 2 is essential for formation and maintenance of memory B cells Journal of Experimental Medicine. 206: 681-689. PMID 19273623 DOI: 10.1084/Jem.20082100 |
0.413 |
|
| 2009 |
Schenten D, Kracker S, Esposito G, Franco S, Klein U, Murphy M, Alt FW, Rajewsky K. Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability. The Journal of Experimental Medicine. 206: 477-90. PMID 19204108 DOI: 10.1084/Jem.20080669 |
0.375 |
|
| 2009 |
Lu LF, Thai TH, Calado DP, Chaudhry A, Kubo M, Tanaka K, Loeb GB, Lee H, Yoshimura A, Rajewsky K, Rudensky AY. Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein Immunity. 30: 80-91. PMID 19144316 DOI: 10.1016/J.Immuni.2008.11.010 |
0.383 |
|
| 2009 |
Ghosh S, Koralov SB, Stevanovic I, Sundrud MS, Sasaki Y, Rajewsky K, Rao A, Mueller MR. Hyperactivable NFAT1 Ameliorates Autoimmune Encephalitis In Vivo. Blood. 114: 711-711. DOI: 10.1182/Blood.V114.22.711.711 |
0.364 |
|
| 2009 |
Sun B, Mallampati S, Gong Y, Wang D, You MJ, Amin HM, Ma Y, Rajewsky K, Lefebvre V, Sun X. Conditional Knockout of Sox4 Markedly Affects B Lymphopoiesis in Adult Mice. Blood. 114: 2524-2524. DOI: 10.1182/Blood.V114.22.2524.2524 |
0.487 |
|
| 2008 |
Wang JH, Alt FW, Gostissa M, Datta A, Murphy M, Alimzhanov MB, Coakley KM, Rajewsky K, Manis JP, Yan CT. Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching. The Journal of Experimental Medicine. 205: 3079-90. PMID 19064702 DOI: 10.1084/Jem.20082271 |
0.457 |
|
| 2008 |
Zemlin M, Schelonka RL, Ippolito GC, Zemlin C, Zhuang Y, Gartland GL, Nitschke L, Pelkonen J, Rajewsky K, Schroeder HW. Regulation of repertoire development through genetic control of D H reading frame preference Journal of Immunology. 181: 8416-8424. PMID 19050259 DOI: 10.4049/Jimmunol.181.12.8416 |
0.313 |
|
| 2008 |
Schelonka RL, Zemlin M, Kobayashi R, Ippolito GC, Zhuang Y, Gartland GL, Szalai A, Fujihashi K, Rajewsky K, Schroeder HW. Preferential use of DH reading frame 2 alters B cell development and antigen-specific antibody production Journal of Immunology. 181: 8409-8415. PMID 19050258 DOI: 10.4049/Jimmunol.181.12.8409 |
0.448 |
|
| 2008 |
Hao Z, Duncan GS, Seagal J, Su YW, Hong C, Haight J, Chen NJ, Elia A, Wakeham A, Li WY, Liepa J, Wood GA, Casola S, Rajewsky K, Mak TW. Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. Immunity. 29: 615-27. PMID 18835195 DOI: 10.1016/J.Immuni.2008.07.016 |
0.5 |
|
| 2008 |
Otipoby KL, Sasaki Y, Schmidt-Supprian M, Patke A, Gareus R, Pasparakis M, Tarakhovsky A, Rajewsky K. BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells Proceedings of the National Academy of Sciences of the United States of America. 105: 12435-12438. PMID 18713867 DOI: 10.1073/Pnas.0805460105 |
0.4 |
|
| 2008 |
Sasaki Y, Calado DP, Derudder E, Zhang B, Shimizu Y, Mackay F, Nishikawa SI, Rajewsky K, Schmidt-Supprian M. NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells Proceedings of the National Academy of Sciences of the United States of America. 105: 10883-10888. PMID 18663224 DOI: 10.1073/Pnas.0805186105 |
0.43 |
|
| 2008 |
Gwack Y, Srikanth S, Oh-Hora M, Hogan PG, Lamperti ED, Yamashita M, Gelinas C, Neems DS, Sasaki Y, Feske S, Prakriya M, Rajewsky K, Rao A. Hair loss and defective T- and B-cell function in mice lacking ORAI1. Molecular and Cellular Biology. 28: 5209-22. PMID 18591248 DOI: 10.1128/Mcb.00360-08 |
0.423 |
|
| 2008 |
Bourgeois C, Hao Z, Rajewsky K, Potocnik AJ, Stockinger B. Ablation of thymic export causes accelerated decay of naïve CD4 T cells in the periphery because of activation by environmental antigen Proceedings of the National Academy of Sciences of the United States of America. 105: 8691-8696. PMID 18562288 DOI: 10.1073/Pnas.0803732105 |
0.359 |
|
| 2008 |
Hömig-Hölzel C, Hojer C, Rastelli J, Casola S, Strobl LJ, Müller W, Quintanilla-Martinez L, Gewies A, Ruland J, Rajewsky K, Zimber-Strobl U. Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis Journal of Experimental Medicine. 205: 1317-1329. PMID 18490492 DOI: 10.1084/Jem.20080238 |
0.426 |
|
| 2008 |
Dorsett Y, McBride KM, Jankovic M, Gazumyan A, Thai TH, Robbiani DF, Di Virgilio M, San-Martin BR, Heidkamp G, Schwickert TA, Eisenreich T, Rajewsky K, Nussenzweig MC. MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh Translocation Immunity. 28: 630-638. PMID 18455451 DOI: 10.1016/J.Immuni.2008.04.002 |
0.332 |
|
| 2008 |
Koralov SB, Muljo SA, Galler GR, Krek A, Chakraborty T, Kanellopoulou C, Jensen K, Cobb BS, Merkenschlager M, Rajewsky N, Rajewsky K. Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage Cell. 132: 860-874. PMID 18329371 DOI: 10.1016/J.Cell.2008.02.020 |
0.5 |
|
| 2008 |
Xiao C, Srinivasan L, Calado DP, Patterson HC, Zhang B, Wang J, Henderson JM, Kutok JL, Rajewsky K. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nature Immunology. 9: 405-14. PMID 18327259 DOI: 10.1038/Ni1575 |
0.773 |
|
| 2008 |
Rastelli J, Hömig-Hölzel C, Seagal J, Müller W, Hermann AC, Rajewsky K, Zimber-Strobl U. LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1 Blood. 111: 1448-1455. PMID 18006702 DOI: 10.1182/Blood-2007-10-117655 |
0.42 |
|
| 2008 |
Mueller MR, Robbs BK, Cruz AL, Sasaki Y, Stevanovic I, Rajewsky K, Viola JP, Rao A. Evidence for NFAT1 as a Tumor Suppressor in T-ALL Blood. 112: 3804-3804. DOI: 10.1182/Blood.V112.11.3804.3804 |
0.439 |
|
| 2008 |
KLEIN U, KÜPPERS R, RAJEWSKY K. Variable-Region Gene Analysis of B-Cell Subsets Derived from a 4-Year-Old Child Annals of the New York Academy of Sciences. 764: 189-191. DOI: 10.1111/J.1749-6632.1995.Tb55825.X |
0.387 |
|
| 2007 |
Edry E, Koralov SB, Rajewsky K, Melamed D. Spontaneous class switch recombination in B cell lymphopoiesis generates aberrant switch junctions and is increased after VDJ rearrangement Journal of Immunology. 179: 6555-6560. PMID 17982044 DOI: 10.4049/Jimmunol.179.10.6555 |
0.479 |
|
| 2007 |
Rajewsky K. From a dream to reality European Journal of Immunology. 37: S134-S137. PMID 17972357 DOI: 10.1002/Eji.200737819 |
0.389 |
|
| 2007 |
Xiao C, Calado DP, Galler G, Thai TH, Patterson HC, Wang J, Rajewsky N, Bender TP, Rajewsky K. MiR-150 Controls B Cell Differentiation by Targeting the Transcription Factor c-Myb Cell. 131: 146-159. PMID 17923094 DOI: 10.1016/j.cell.2007.07.021 |
0.767 |
|
| 2007 |
Yan CT, Boboila C, Souza EK, Franco S, Hickernell TR, Murphy M, Gumaste S, Geyer M, Zarrin AA, Manis JP, Rajewsky K, Alt FW. IgH class switching and translocations use a robust non-classical end-joining pathway. Nature. 449: 478-82. PMID 17713479 DOI: 10.1038/Nature06020 |
0.382 |
|
| 2007 |
French CA, Groszer M, Preece C, Coupe AM, Rajewsky K, Fisher SE. Generation of mice with a conditional Foxp2 null allele. Genesis (New York, N.Y. : 2000). 45: 440-6. PMID 17619227 DOI: 10.1002/Dvg.20305 |
0.343 |
|
| 2007 |
Pao LI, Lam KP, Henderson JM, Kutok JL, Alimzhanov M, Nitschke L, Thomas ML, Neel BG, Rajewsky K. B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity. 27: 35-48. PMID 17600736 DOI: 10.1016/J.Immuni.2007.04.016 |
0.454 |
|
| 2007 |
Schmidt-Supprian M, Rajewsky K. Vagaries of conditional gene targeting Nature Immunology. 8: 665-668. PMID 17579640 DOI: 10.1038/Ni0707-665 |
0.302 |
|
| 2007 |
Greve B, Weissert R, Hamdi N, Bettelli E, Sobel RA, Coyle A, Kuchroo VK, Rajewsky K, Schmidt-Supprian M. I kappa B kinase 2/beta deficiency controls expansion of autoreactive T cells and suppresses experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 179: 179-85. PMID 17579036 DOI: 10.4049/Jimmunol.179.1.179 |
0.437 |
|
| 2007 |
Fraenkel S, Mostoslavsky R, Novobrantseva TI, Pelanda R, Chaudhuri J, Esposito G, Jung S, Alt FW, Rajewsky K, Cedar H, Bergman Y. Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. Nature Immunology. 8: 715-22. PMID 17546032 DOI: 10.1038/Ni1476 |
0.635 |
|
| 2007 |
Schmidt-Supprian M, Wunderlich FT, Rajewsky K. Excision of the Frt-flanked neoR cassette from the CD19cre knock-in transgene reduces Cre-mediated recombination Transgenic Research. 16: 657-660. PMID 17541717 DOI: 10.1007/S11248-007-9100-4 |
0.38 |
|
| 2007 |
Liu H, Schmidt-Supprian M, Shi Y, Hobeika E, Barteneva N, Jumaa H, Pelanda R, Reth M, Skok J, Rajewsky K. Yin Yang 1 is a critical regulator of B-cell development Genes and Development. 21: 1179-1189. PMID 17504937 DOI: 10.1101/Gad.1529307 |
0.414 |
|
| 2007 |
Thai TH, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy A, Frendewey D, Valenzuela D, Kutok JL, Schmidt-Supprian M, Rajewsky N, Yancopoulos G, Rao A, Rajewsky K. Regulation of the germinal center response by microRNA-155. Science (New York, N.Y.). 316: 604-8. PMID 17463289 DOI: 10.1126/Science.1141229 |
0.347 |
|
| 2007 |
Waisman A, Kraus M, Seagal J, Ghosh S, Melamed D, Song J, Sasaki Y, Classen S, Lutz C, Brombacher F, Nitschke L, Rajewsky K. IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta. The Journal of Experimental Medicine. 204: 747-58. PMID 17420268 DOI: 10.1084/Jem.20062024 |
0.497 |
|
| 2007 |
Sasaki Y, Schmidt-Supprian M, Derudder E, Rajewsky K. Role of NFkappaB signaling in normal and malignant B cell development. Advances in Experimental Medicine and Biology. 596: 149-154. PMID 17338183 DOI: 10.1007/0-387-46530-8_13 |
0.489 |
|
| 2007 |
Mueller MR, Sasaki Y, Sharma S, Ghosh S, Gelinas C, Lamperti EL, Rajewsky K, Rao A. Expression of Hyperactivable NFAT1 from the ROSA26 Locus Leads to Detrimental Effects during Embryonic Development. Blood. 110: 2296-2296. DOI: 10.1182/Blood.V110.11.2296.2296 |
0.421 |
|
| 2006 |
Mora JR, Iwata M, Eksteen B, Song SY, Junt T, Senman B, Otipoby KL, Yokota A, Takeuchi H, Ricciardi-Castagnoli P, Rajewsky K, Adams DH, Von Andrian UH. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells Science. 314: 1157-1160. PMID 17110582 DOI: 10.1126/Science.1132742 |
0.425 |
|
| 2006 |
Casola S, Rajewsky K. B cell recruitment and selection in mouse GALT germinal centers Current Topics in Microbiology and Immunology. 308: 155-171. PMID 16922090 DOI: 10.1007/3-540-30657-9_7 |
0.503 |
|
| 2006 |
Baxter FO, Came PJ, Abell K, Kedjouar B, Huth M, Rajewsky K, Pasparakis M, Watson CJ. IKKβ/2 induces TWEAK and apoptosis in mammary epithelial cells Development. 133: 3485-3494. PMID 16887827 DOI: 10.1242/Dev.02502 |
0.306 |
|
| 2006 |
Patterson HCK, Kraus M, Kim YM, Ploegh H, Rajewsky K. The B Cell Receptor Promotes B Cell Activation and Proliferation through a Non-ITAM Tyrosine in the Igα Cytoplasmic Domain Immunity. 25: 55-65. PMID 16860757 DOI: 10.1016/J.Immuni.2006.04.014 |
0.821 |
|
| 2006 |
Sasaki Y, Derudder E, Hobeika E, Pelanda R, Reth M, Rajewsky K, Schmidt-Supprian M. Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation Immunity. 24: 729-739. PMID 16782029 DOI: 10.1016/J.Immuni.2006.04.005 |
0.401 |
|
| 2006 |
Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R. Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination Nature Immunology. 7: 773-782. PMID 16767092 DOI: 10.1038/Ni1357 |
0.438 |
|
| 2006 |
Ippolito GC, Schelonka RL, Zemlin M, Ivanov II, Kobayashi R, Zemlin C, Gartland GL, Nitschke L, Pelkonen J, Fujihashi K, Rajewsky K, Schroeder HW. Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production Journal of Experimental Medicine. 203: 1567-1578. PMID 16754718 DOI: 10.1084/Jem.20052217 |
0.442 |
|
| 2006 |
Casola S, Cattoretti G, Uyttersprot N, Koralov SB, Seagal J, Segal J, Hao Z, Waisman A, Egert A, Ghitza D, Rajewsky K. Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting. Proceedings of the National Academy of Sciences of the United States of America. 103: 7396-401. PMID 16651521 DOI: 10.1073/Pnas.0602353103 |
0.551 |
|
| 2006 |
Schenten D, Egert A, Pasparakis M, Rajewsky K. M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice Blood. 107: 4849-4856. PMID 16493007 DOI: 10.1182/Blood-2005-10-4154 |
0.526 |
|
| 2006 |
Victoratos P, Lagnel J, Tzima S, Alimzhanov MB, Rajewsky K, Pasparakis M, Kollias G. FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses Immunity. 24: 66-77. PMID 16413924 DOI: 10.1016/J.Immuni.2005.11.013 |
0.371 |
|
| 2006 |
Mueller MR, Sasaki Y, Sharma S, Rajewsky K, Rao A. The Role of the Transcription Factor NFAT in the Pathogenesis of Non-Hodgkin’s Lymphomas. Blood. 108: 2371-2371. DOI: 10.1182/Blood.V108.11.2371.2371 |
0.375 |
|
| 2005 |
Schelonka RL, Ivanov II, Jung DH, Ippolito GC, Nitschke L, Zhuang Y, Gartland GL, Pelkonen J, Alt FW, Rajewsky K, Schroeder HW. A single DH gene segment creates its own unique CDR-H3 repertoire and is sufficient for B cell development and immune function. Journal of Immunology (Baltimore, Md. : 1950). 175: 6624-32. PMID 16272317 DOI: 10.4049/Jimmunol.175.10.6624 |
0.487 |
|
| 2005 |
Thomas MD, Kremer CS, Ravichandran KS, Rajewsky K, Bender TP. c-Myb is critical for B cell development and maintenance of follicular B cells. Immunity. 23: 275-86. PMID 16169500 DOI: 10.1016/J.Immuni.2005.08.005 |
0.459 |
|
| 2005 |
Monticelli S, Ansel KM, Xiao C, Socci ND, Krichevsky AM, Thai TH, Rajewsky N, Marks DS, Sander C, Rajewsky K, Rao A, Kosik KS. MicroRNA profiling of the murine hematopoietic system. Genome Biology. 6: R71. PMID 16086853 DOI: 10.1186/Gb-2005-6-8-R71 |
0.35 |
|
| 2005 |
Muljo SA, Ansel KM, Kanellopoulou C, Livingston DM, Rao A, Rajewsky K. Aberrant T cell differentiation in the absence of Dicer. The Journal of Experimental Medicine. 202: 261-9. PMID 16009718 DOI: 10.1084/Jem.20050678 |
0.409 |
|
| 2005 |
Oberdoerffer P, Kanellopoulou C, Heissmeyer V, Paeper C, Borowski C, Aifantis I, Rao A, Rajewsky K. Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages Molecular and Cellular Biology. 25: 3896-3905. PMID 15870264 DOI: 10.1128/Mcb.25.10.3896-3905.2005 |
0.358 |
|
| 2005 |
Tze LE, Schram BR, Lam KP, Hogquist KA, Hippen KL, Liu J, Shinton SA, Otipoby KL, Rodine PR, Vegoe AL, Kraus M, Hardy RR, Schlissel MS, Rajewsky K, Behrens TW. Basal immunoglobulin signaling actively maintains developmental stage in immature B cells. Plos Biology. 3: e82. PMID 15752064 DOI: 10.1371/Journal.Pbio.0030082 |
0.485 |
|
| 2005 |
Mandal M, Borowski C, Palomero T, Ferrando AA, Oberdoerffer P, Meng F, Ruiz-Vela A, Ciofani M, Zuniga-Pflucker JC, Screpanti I, Look AT, Korsmeyer SJ, Rajewsky K, Von Boehmer H, Aifantis I. The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival Journal of Experimental Medicine. 201: 603-614. PMID 15728238 DOI: 10.1084/Jem.20041924 |
0.383 |
|
| 2005 |
Kanellopoulou C, Muljo SA, Kung AL, Ganesan S, Drapkin R, Jenuwein T, Livingston DM, Rajewsky K. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes & Development. 19: 489-501. PMID 15713842 DOI: 10.1101/Gad.1248505 |
0.385 |
|
| 2005 |
Koralov SB, Novobrantseva TI, Hochedlinger K, Jaenisch R, Rajewsky K. Direct in vivo VH to JH rearrangement violating the 12/23 rule. The Journal of Experimental Medicine. 201: 341-8. PMID 15699070 DOI: 10.1084/Jem.20041577 |
0.429 |
|
| 2005 |
Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R. IRF-4/MUM-1 Expression Is a Critical Switch in the Generation of Plasma Cells Versus Memory B-Cells. Blood. 106: 337-337. DOI: 10.1182/Blood.V106.11.337.337 |
0.533 |
|
| 2004 |
Roers A, Siewe L, Strittmatter E, Deckert M, Schlüter D, Stenzel W, Gruber AD, Krieg T, Rajewsky K, Müller W. T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. The Journal of Experimental Medicine. 200: 1289-97. PMID 15534372 DOI: 10.1084/Jem.20041789 |
0.349 |
|
| 2004 |
Mostoslavsky R, Alt FW, Rajewsky K. The lingering enigma of the allelic exclusion mechanism. Cell. 118: 539-44. PMID 15339659 DOI: 10.1016/J.Cell.2004.08.023 |
0.422 |
|
| 2004 |
Sasaki Y, Casola S, Kutok JL, Rajewsky K, Schmidt-Supprian M. TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology Journal of Immunology. 173: 2245-2252. PMID 15294936 DOI: 10.4049/Jimmunol.173.4.2245 |
0.455 |
|
| 2004 |
Schmidt-Supprian M, Tian J, Ji H, Terhorst C, Bhan AK, Grant EP, Pasparakis M, Casola S, Coyle AJ, Rajewsky K. IκB kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion Journal of Immunology. 173: 1612-1619. PMID 15265889 DOI: 10.4049/Jimmunol.173.3.1612 |
0.451 |
|
| 2004 |
Bender TP, Kremer CS, Kraus M, Buch T, Rajewsky K. Critical functions for c-Myb at three checkpoints during thymocyte development Nature Immunology. 5: 721-729. PMID 15195090 DOI: 10.1038/Ni1085 |
0.345 |
|
| 2004 |
Kraus M, Alimzhanov MB, Rajewsky N, Rajewsky K. Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer Cell. 117: 787-800. PMID 15186779 DOI: 10.1016/J.Cell.2004.05.014 |
0.474 |
|
| 2004 |
Hao Z, Hampel B, Yagita H, Rajewsky K. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis Journal of Experimental Medicine. 199: 1355-1365. PMID 15148335 DOI: 10.1084/Jem.20032196 |
0.408 |
|
| 2004 |
Schmidt-Supprian M, Tian J, Grant EP, Pasparakis M, Maehr R, Ovaa H, Ploegh HL, Coyle AJ, Rajewsky K. Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-κB activation Proceedings of the National Academy of Sciences of the United States of America. 101: 4566-4571. PMID 15070758 DOI: 10.1073/Pnas.0400885101 |
0.396 |
|
| 2004 |
Reichlin A, Gazumyan A, Nagaoka H, Kirsch KH, Kraus M, Rajewsky K, Nussenzweig MC. A B cell receptor with two Igalpha cytoplasmic domains supports development of mature but anergic B cells. The Journal of Experimental Medicine. 199: 855-65. PMID 15024049 DOI: 10.1084/Jem.20031140 |
0.494 |
|
| 2004 |
Skulina C, Schmidt S, Dornmair K, Babbe H, Roers A, Rajewsky K, Wekerle H, Hohlfeld R, Goebels N. Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proceedings of the National Academy of Sciences of the United States of America. 101: 2428-33. PMID 14983026 DOI: 10.1073/Pnas.0308689100 |
0.326 |
|
| 2004 |
Casola S, Otipoby KL, Alimzhanov M, Humme S, Uyttersprot N, Kutok JL, Carroll MC, Rajewsky K. B cell receptor signal strength determines B cell fate Nature Immunology. 5: 317-327. PMID 14758357 DOI: 10.1038/Ni1036 |
0.488 |
|
| 2003 |
Oberdoerffer P, Otipoby KL, Maruyama M, Rajewsky K. Unidirectional Cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71 Nucleic Acids Research. 31: e140. PMID 14602933 DOI: 10.1093/Nar/Gng140 |
0.379 |
|
| 2003 |
Kanters E, Pasparakis M, Gijbels MJJ, Vergouwe MN, Partouns-Hendriks I, Fijneman RJA, Clausen BE, Förster I, Kockx MM, Rajewsky K, Kraal G, Hofker MH, De Winther MPJ. Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice Journal of Clinical Investigation. 112: 1176-1185. PMID 14561702 DOI: 10.1172/Jci18580 |
0.316 |
|
| 2003 |
Apostolou I, Hao Z, Rajewsky K, Von Boehmer H. Effective destruction of Fas-deficient insulin-producing β cells in type 1 diabetes Journal of Experimental Medicine. 198: 1103-1106. PMID 14530378 DOI: 10.1084/Jem.20030698 |
0.33 |
|
| 2003 |
Schmidt-Supprian M, Courtois G, Tian J, Coyle AJ, Israël A, Rajewsky K, Pasparakis M. Mature T cells depend on signaling through the IKK complex Immunity. 19: 377-389. PMID 14499113 DOI: 10.1016/S1074-7613(03)00237-1 |
0.365 |
|
| 2003 |
Schwering I, Bräuninger A, Distler V, Jesdinsky J, Diehl V, Hansmann ML, Rajewsky K, Küppers R. Profiling of Hodgkin's lymphoma cell line l1236 and germinal center B cells: Identification of Hodgkin's lymphoma-specific genes Molecular Medicine. 9: 85-95. PMID 12865944 DOI: 10.1007/Bf03402041 |
0.438 |
|
| 2003 |
Oberdoerffer P, Novobrantseva TI, Rajewsky K. Expression of a targeted λ1 light chain gene is developmentally regulated and independent of Igκ rearrangements Journal of Experimental Medicine. 197: 1165-1172. PMID 12719477 DOI: 10.1084/Jem.20030402 |
0.403 |
|
| 2003 |
Bräuninger A, Wacker HH, Rajewsky K, Küppers R, Hansmann ML. Typing the histogenetic origin of the tumor cells of lymphocyte-rich classical Hodgkin's lymphoma in relation to tumor cells of classical and lymphocyte-predominance Hodgkin's lymphoma Cancer Research. 63: 1644-1651. PMID 12670918 |
0.352 |
|
| 2003 |
Kurth J, Hansmann ML, Rajewsky K, Küppers R. Epstein-Barr virus-infected B cells expanding in germinal centers of infectious mononucleosis patients do not participate in the germinal center reaction Proceedings of the National Academy of Sciences of the United States of America. 100: 4730-4735. PMID 12665622 DOI: 10.1073/Pnas.2627966100 |
0.461 |
|
| 2003 |
Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-I Nature Immunology. 4: 321-329. PMID 12612580 DOI: 10.1038/Ni907 |
0.373 |
|
| 2003 |
Seibler J, Zevnik B, Küter-Luks B, Andreas S, Kern H, Hennek T, Rode A, Heimann C, Faust N, Kauselmann G, Schoor M, Jaenisch R, Rajewsky K, Kühn R, Schwenk F. Rapid generation of inducible mouse mutants. Nucleic Acids Research. 31: e12. PMID 12582257 DOI: 10.1093/Nar/Gng012 |
0.39 |
|
| 2003 |
Schwering I, Bräuninger A, Klein U, Jungnickel B, Tinguely M, Diehl V, Hansmann ML, Dalla-Favera R, Rajewsky K, Küppers R. Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma Blood. 101: 1505-1512. PMID 12393731 DOI: 10.1182/Blood-2002-03-0839 |
0.503 |
|
| 2003 |
Schwering I, Bräuninger A, Distler V, Jesdinsky J, Diehl V, Hansmann M, Rajewsky K, Küppers R. Erratum to: Profiling of Hodgkin’s Lymphoma Cell Line L1236 and Germinal Center B Cells: Identification of Hodgkin’s Lymphoma-specific Genes Molecular Medicine. 9: 235-235. DOI: 10.1007/BF03402132 |
0.313 |
|
| 2002 |
Schenten D, Gerlach VL, Guo C, Velasco-Miguel S, Hladik CL, White CL, Friedberg EC, Rajewsky K, Esposito G. DNA polymerase K deficiency does not affect somatic hypermutation in mice European Journal of Immunology. 32: 3152-3160. PMID 12555660 DOI: 10.1002/1521-4141(200211)32:11<3152::Aid-Immu3152>3.0.Co;2-2 |
0.381 |
|
| 2002 |
Kurth J, Perniok A, Schmitz R, Iking-Konert C, Chiorazzi N, Thompson KM, Winkler T, Rajewsky K, Küppers R. Lack of deleterious somatic mutations in the CD95 gene of plasmablasts from systemic lupus erythematosus patients and autoantibody-producing cell lines. European Journal of Immunology. 32: 3785-92. PMID 12516573 DOI: 10.1002/1521-4141(200212)32:12<3785::Aid-Immu3785>3.0.Co;2-E |
0.405 |
|
| 2002 |
Schönig K, Schwenk F, Rajewsky K, Bujard H. Stringent doxycycline dependent control of CRE recombinase in vivo Nucleic Acids Research. 30: e134. PMID 12466566 DOI: 10.1093/Nar/Gnf134 |
0.367 |
|
| 2002 |
Kuprash DV, Alimzhanov MB, Tumanov AV, Grivennikov SI, Shakhov AN, Drutskaya LN, Marino MW, Turetskaya RL, Anderson AO, Rajewsky K, Pfeffer K, Nedospasov SA. Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice. Molecular and Cellular Biology. 22: 8626-34. PMID 12446781 DOI: 10.1128/Mcb.22.24.8626-8634.2002 |
0.369 |
|
| 2002 |
Hasan M, Polic B, Bralic M, Jonjic S, Rajewsky K. Incomplete block of B cell development and immunoglobulin production in mice carrying the μMT mutation on the BALB/c background European Journal of Immunology. 32: 3463-3471. PMID 12442328 DOI: 10.1002/1521-4141(200212)32:12<3463::Aid-Immu3463>3.0.Co;2-B |
0.479 |
|
| 2002 |
Feldhahn N, Schwering I, Lee S, Wartenberg M, Klein F, Wang H, Zhou G, Wang SM, Rowley JD, Hescheler J, Krönke M, Rajewsky K, Küppers R, Müschen M. Silencing of B cell receptor signals in human naive B cells. The Journal of Experimental Medicine. 196: 1291-305. PMID 12438421 DOI: 10.1084/Jem.20020881 |
0.478 |
|
| 2002 |
Pasparakis M, Schmidt-Supprian M, Rajewsky K. IκB kinase signaling is essential for maintenance of mature B cells Journal of Experimental Medicine. 196: 743-752. PMID 12235208 DOI: 10.1084/Jem.20020907 |
0.413 |
|
| 2002 |
Küppers R, Schwering I, Bräuninger A, Rajewsky K, Hansmann ML. Biology of Hodgkin's lymphoma Annals of Oncology. 13: 11-18. PMID 12078890 DOI: 10.1093/Annonc/13.S1.11 |
0.495 |
|
| 2002 |
Pasparakis M, Courtois G, Hafner M, Schmidt-Supprian M, Nenci A, Toksoy A, Krampert M, Goebeler M, Gillitzer R, Israel A, Krieg T, Rajewsky K, Haase I. TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2 Nature. 417: 861-866. PMID 12075355 DOI: 10.1038/Nature00820 |
0.404 |
|
| 2002 |
Buch T, Rieux-Laucat F, Förster I, Rajewsky K. Failure of HY-specific thymocytes to escape negative selection by receptor editing Immunity. 16: 707-718. PMID 12049722 DOI: 10.1016/S1074-7613(02)00312-6 |
0.336 |
|
| 2002 |
Müschen M, Rajewsky K, Krönke M, Küppers R. The origin of CD95-gene mutations in B-cell lymphoma. Trends in Immunology. 23: 75-80. PMID 11929130 DOI: 10.1016/S1471-4906(01)02115-9 |
0.421 |
|
| 2002 |
Peitz M, Pfannkuche K, Rajewsky K, Edenhofer F. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes Proceedings of the National Academy of Sciences of the United States of America. 99: 4489-4494. PMID 11904364 DOI: 10.1073/Pnas.032068699 |
0.326 |
|
| 2001 |
Goossens T, Bräuninger A, Klein U, Küppers R, Rajewsky K. Receptor revision plays no major role in shaping the receptor repertoire of human memory B cells after the onset of somatic hypermutation European Journal of Immunology. 31: 3638-3648. PMID 11745384 DOI: 10.1002/1521-4141(200112)31:12<3638::Aid-Immu3638>3.0.Co;2-G |
0.456 |
|
| 2001 |
Bräuninger A, Goossens T, Rajewsky K, Küppers R. Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human European Journal of Immunology. 31: 3631-3637. PMID 11745383 DOI: 10.1002/1521-4141(200112)31:12<3631::Aid-Immu3631>3.0.Co;2-L |
0.455 |
|
| 2001 |
Hao Z, Rajewsky K. Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow Journal of Experimental Medicine. 194: 1151-1163. PMID 11602643 DOI: 10.1084/Jem.194.8.1151 |
0.48 |
|
| 2001 |
Bräuninger A, Spieker T, Willenbrock K, Gaulard P, Wacker HH, Rajewsky K, Hansmann ML, Küppers R. Survival and clonal expansion of mutating "forbidden" (immunoglobulin receptor-deficient) Epstein-Barr virus-infected B cells in angioimmunoblastic T cell lymphoma Journal of Experimental Medicine. 194: 927-940. PMID 11581315 DOI: 10.1084/Jem.194.7.927 |
0.483 |
|
| 2001 |
Kraus M, Pao LI, Reichlin A, Hu Y, Canono B, Cambier JC, Nussenzweig MC, Rajewsky K. Interference with immunoglobulin (Ig)α immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igβ cytoplasmic tail Journal of Experimental Medicine. 194: 455-469. PMID 11514602 DOI: 10.1084/Jem.194.4.455 |
0.496 |
|
| 2001 |
Küppers R, Sousa AB, Baur AS, Strickler JG, Rajewsky K, Hansmann ML. Common germinal-center B-cell origin of the malignant cells in two composite lymphomas, involving classical hodgkin's disease and either follicular lymphoma or B-CLL Molecular Medicine. 7: 285-292. PMID 11474574 DOI: 10.1007/Bf03402211 |
0.415 |
|
| 2001 |
Polic B, Kunkel D, Scheffold A, Rajewsky K. How alpha beta T cells deal with induced TCR alpha ablation. Proceedings of the National Academy of Sciences of the United States of America. 98: 8744-9. PMID 11447257 DOI: 10.1073/Pnas.141218898 |
0.375 |
|
| 2001 |
Wunderlich FT, Wildner H, Rajewsky K, Edenhofer F. New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility Nucleic Acids Research. 29: E47. PMID 11353092 DOI: 10.1093/Nar/29.10.E47 |
0.307 |
|
| 2001 |
Müschen M, Küppers R, Spieker T, Bräuninger A, Rajewsky K, Hansmann ML. Molecular single-cell analysis of Hodgkin- and Reed-Sternberg cells harboring unmutated immunoglobulin variable region genes Laboratory Investigation. 81: 289-295. PMID 11310822 DOI: 10.1038/Labinvest.3780237 |
0.44 |
|
| 2001 |
Casellas R, Shih TA, Kleinewietfeld M, Rakonjac J, Nemazee D, Rajewsky K, Nussenzweig MC. Contribution of receptor editing to the antibody repertoire. Science (New York, N.Y.). 291: 1541-4. PMID 11222858 DOI: 10.1126/Science.1056600 |
0.431 |
|
| 2001 |
Jacobs H, Rajewsky K, Fukita Y, Bross L. Indirect and direct evidence for DNA double-strand breaks in hypermutating immunoglobulin genes Philosophical Transactions of the Royal Society B: Biological Sciences. 355: 119-125. PMID 11205324 DOI: 10.1098/Rstb.2000.0756 |
0.321 |
|
| 2001 |
de Alboran IM, O'Hagan RC, Gärtner F, Malynn B, Davidson L, Rickert R, Rajewsky K, DePinho RA, Alt FW. Analysis of C-MYC function in normal cells via conditional gene-targeted mutation. Immunity. 14: 45-55. PMID 11163229 DOI: 10.1016/S1074-7613(01)00088-7 |
0.434 |
|
| 2001 |
Küppers R, Bräuninger A, Müschen M, Distler V, Hansmann ML, Rajewsky K. Evidence that Hodgkin and Reed-Sternberg cells in Hodgkin disease do not represent cell fusions Blood. 97: 818-821. PMID 11157505 DOI: 10.1182/Blood.V97.3.818 |
0.456 |
|
| 2001 |
Bräuninger A, Yang W, Wacker HH, Rajewsky K, Küppers R, Hansmann ML. B-cell development in progressively transformed germinal centers: Similarities and differences compared with classical germinal centers and lymphocyte-predominant Hodgkin disease Blood. 97: 714-719. PMID 11157489 DOI: 10.1182/Blood.V97.3.714 |
0.497 |
|
| 2001 |
Reichlin A, Hu Y, Meffre E, Nagaoka H, Gong S, Kraus M, Rajewsky K, Nussenzweig MC. B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin β Journal of Experimental Medicine. 193: 13-23. PMID 11136817 DOI: 10.1084/Jem.193.1.13 |
0.426 |
|
| 2000 |
Müschen M, Re D, Jungnickel B, Diehl V, Rajewsky K, Küppers R. Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction Journal of Experimental Medicine. 192: 1833-1839. PMID 11120779 DOI: 10.1084/Jem.192.12.1833 |
0.422 |
|
| 2000 |
Bross L, Fukita Y, McBlane F, Démollière C, Rajewsky K, Jacobs H. DNA double-strand breaks in immunoglobulin genes undergoing somatic hypermutation Immunity. 13: 589-597. PMID 11114372 DOI: 10.1016/S1074-7613(00)00059-5 |
0.398 |
|
| 2000 |
Kurth J, Spieker T, Wustrow J, Strickler JG, Hansmann ML, Rajewsky K, Küppers R. EBV-infected B cells in infectious mononucleosis: Viral strategies for spreading in the B cell compartment and establishing latency Immunity. 13: 485-495. PMID 11070167 DOI: 10.1016/S1074-7613(00)00048-0 |
0.442 |
|
| 2000 |
Geiger KD, Klein U, Bräuninger A, Berger S, Leder K, Rajewsky K, Hansmann ML, Küppers R. CD5-positive B cells in healthy elderly humans are a polyclonal B cell population European Journal of Immunology. 30: 2918-2923. PMID 11069074 DOI: 10.1002/1521-4141(200010)30:10<2918::Aid-Immu2918>3.0.Co;2-C |
0.421 |
|
| 2000 |
Esposito G, Godin I, Klein U, Yaspo ML, Cumano A, Rajewsky K. Disruption of the Rev3l-encoded catalytic subunit of polymerase ζ in mice results in early embryonic lethality Current Biology. 10: 1221-1224. PMID 11050393 DOI: 10.1016/S0960-9822(00)00726-0 |
0.387 |
|
| 2000 |
Spieker T, Kurth J, Kuppers R, Rajewsky K, Brauninger A, Hansmann ML. Molecular single-cell analysis of the clonal relaionship of small Epstein-Barr virus-infected cells and Epstein-Barr virus-harboring Hodgkin and Reed/Sternberg cells in Hodgkin disease Blood. 96: 3133-3138. PMID 11049994 DOI: 10.1182/Blood.V96.9.3133.H8003133_3133_3138 |
0.43 |
|
| 2000 |
Maruyama M, Lam KP, Rajewsky K. Memory B-cell persistence is independent of persisting immunizing antigen Nature. 407: 636-642. PMID 11034213 DOI: 10.1038/35036600 |
0.44 |
|
| 2000 |
Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, Friese M, Schröder R, Deckert M, Schmidt S, Ravid R, Rajewsky K. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. The Journal of Experimental Medicine. 192: 393-404. PMID 10934227 DOI: 10.1084/Jem.192.3.393 |
0.344 |
|
| 2000 |
Schmidt-Supprian M, Bloch W, Courtois G, Addicks K, Israël A, Rajewsky K, Pasparakis M. NEMO/IKKγ-deficient mice model incontinentia pigmenti Molecular Cell. 5: 981-992. PMID 10911992 DOI: 10.1016/S1097-2765(00)80263-4 |
0.345 |
|
| 2000 |
Vosshenrich CAJ, Sharara LI, Guy-Grand D, Rajewsky K, Müller W, Di Santo JP. Common cytokine receptor γ chain (γ(c))-deficient B cells persist in T cell-deficient γ(c)- mice and respond to a T-independent antigen European Journal of Immunology. 30: 1614-1622. PMID 10898497 DOI: 10.1002/1521-4141(200006)30:6<1614::Aid-Immu1614>3.0.Co;2-I |
0.49 |
|
| 2000 |
Ogata H, Su IH, Miyake K, Nagai Y, Akashi S, Mecklenbräuker I, Rajewsky K, Kimoto M, Tarakhovsky A. The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells Journal of Experimental Medicine. 192: 23-29. PMID 10880523 DOI: 10.1084/Jem.192.1.23 |
0.402 |
|
| 2000 |
Willenbrock K, Roers A, Blohbaum B, Rajewsky K, Hansmann ML. CD8+ T cells in Hodgkin's disease tumor tissue are a polyclonal population with limited clonal expansion but little evidence of selection by antigen American Journal of Pathology. 157: 171-175. PMID 10880387 DOI: 10.1016/S0002-9440(10)64528-2 |
0.367 |
|
| 2000 |
Braun U, Rajewsky K, Pelanda R. Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes Proceedings of the National Academy of Sciences of the United States of America. 97: 7429-7434. PMID 10829061 DOI: 10.1073/Pnas.050578497 |
0.444 |
|
| 2000 |
Roers A, Hansmann ML, Rajewsky K, Küppers R. Single-cell PCR analysis of T helper cells in human lymph node germinal centers American Journal of Pathology. 156: 1067-1071. PMID 10702422 DOI: 10.1016/S0002-9440(10)64974-7 |
0.42 |
|
| 2000 |
Esposito G, Texido G, Betz UAK, Gu H, Müller W, Klein U, Rajewsky K. Mice reconstituted with DNA polymerase β-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally Proceedings of the National Academy of Sciences of the United States of America. 97: 1166-1171. PMID 10655502 DOI: 10.1073/Pnas.97.3.1166 |
0.443 |
|
| 2000 |
Texido G, Su IH, Mecklenbräuker I, Saijo K, Malek SN, Desiderio S, Rajewsky K, Tarakhovsky A. The B-cell-specific Src-family kinase Blk is dispensable for B-cell development and activation. Molecular and Cellular Biology. 20: 1227-33. PMID 10648608 DOI: 10.1128/Mcb.20.4.1227-1233.2000 |
0.514 |
|
| 2000 |
Kanzler H, Küppers R, Helmes S, Wacker HH, Chott A, Hansmann ML, Rajewsky K. Hodgkin and Reed-Sternberg-like cells in B-cell chronic lymphocytic leukemia represent the outgrowth of single germinal-center B-cell-derived clones: Potential precursors of Hodgkin and Reed-Sternberg cells in Hodgkin's disease Blood. 95: 1023-1031. PMID 10648418 DOI: 10.1182/Blood.V95.3.1023.003K07_1023_1031 |
0.494 |
|
| 2000 |
Jungnickel B, Staratschek-Jox A, Bräuninger A, Spieker T, Wolf J, Diehl V, Hansmann ML, Rajewsky K, Küppers R. Clonal deleterious mutations in the iκbα gene in the malignant cells in Hodgkin's lymphoma Journal of Experimental Medicine. 191: 395-401. PMID 10637284 DOI: 10.1084/Jem.191.2.395 |
0.375 |
|
| 2000 |
Müschen M, Rajewsky K, Bräuninger A, Baur AS, Oudejans JJ, Roers A, Hansmann ML, Küppers R. Rare occurrence of classical Hodgkin's disease as a T cell lymphoma Journal of Experimental Medicine. 191: 387-394. PMID 10637283 DOI: 10.1084/Jem.191.2.387 |
0.43 |
|
| 1999 |
Kraus M, Saijo K, Torres RM, Rajewsky K. Ig-alpha cytoplasmic truncation renders immature B cells more sensitive to antigen contact. Immunity. 11: 537-45. PMID 10591179 DOI: 10.1016/S1074-7613(00)80129-6 |
0.457 |
|
| 1999 |
Küppers R, Klein U, Hansmann ML, Rajewsky K. Cellular origin of human B-cell lymphomas New England Journal of Medicine. 341: 1520-1529. PMID 10559454 DOI: 10.1056/Nejm199911113412007 |
0.466 |
|
| 1999 |
Montesinos-Rongen M, Roers A, Küppers R, Rajewsky K, Hansmann ML. Mutation of the p53 gene is not a typical feature of Hodgkin and Reed- Sternberg cells in Hodgkin's disease Blood. 94: 1755-1760. PMID 10477701 DOI: 10.1182/Blood.V94.5.1755.417A26_1755_1760 |
0.351 |
|
| 1999 |
Lam KP, Rajewsky K. B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development Journal of Experimental Medicine. 190: 471-477. PMID 10449518 DOI: 10.1084/Jem.190.4.471 |
0.435 |
|
| 1999 |
Jacobs H, Puglisi A, Rajewsky K, Fukita Y. Tuning somatic hypermutation by transcription. Current Topics in Microbiology and Immunology. 246: 149-58; discussion 1. PMID 10396051 DOI: 10.1007/978-3-642-60162-0_19 |
0.381 |
|
| 1999 |
Klein U, Rajewsky K, Küppers R. Phenotypic and molecular characterization of human peripheral blood B-cell subsets with special reference to N-region addition and J kappa-usage in V kappa J kappa-joints and kappa/lambda-ratios in naive versus memory B-cell subsets to identify traces of receptor editing processes. Current Topics in Microbiology and Immunology. 246: 141-6; discussion 14. PMID 10396050 DOI: 10.1007/978-3-642-60162-0_18 |
0.485 |
|
| 1999 |
Korganow AS, Ji H, Mangialaio S, Duchatelle V, Pelanda R, Martin T, Degott C, Kikutani H, Rajewsky K, Pasquali JL, Benoist C, Mathis D. From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity. 10: 451-61. PMID 10229188 DOI: 10.1016/S1074-7613(00)80045-X |
0.407 |
|
| 1999 |
Bräuninger A, Hansmann ML, Strickler JG, Dummer R, Burg G, Rajewsky K, Küppers R. Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's lymphoma. The New England Journal of Medicine. 340: 1239-47. PMID 10210707 DOI: 10.1056/Nejm199904223401604 |
0.393 |
|
| 1999 |
Qin XF, Schwers S, Yu W, Papavasiliou F, Suh H, Nussenzweig A, Rajewsky K, Nussenzweig MC. Secondary V(D)J recombination in B-1 cells. Nature. 397: 355-9. PMID 9950428 DOI: 10.1038/16933 |
0.51 |
|
| 1999 |
Küppers R, Hansmann ML, Rajewsky K. Clonality and germinal centre B-cell derivation of Hodgkin/Reed-Sternberg cells in Hodgkin's disease. Annals of Oncology : Official Journal of the European Society For Medical Oncology. S17-20. PMID 9926232 DOI: 10.1093/Annonc/9.Suppl_5.S17 |
0.479 |
|
| 1999 |
Endres R, Alimzhanov MB, Plitz T, Fütterer A, Kosco-Vilbois MH, Nedospasov SA, Rajewsky K, Pfeffer K. Mature Follicular Dendritic Cell Networks Depend on Expression of Lymphotoxin β Receptor by Radioresistant Stromal Cells and of Lymphotoxin β and Tumor Necrosis Factor by B Cells Journal of Experimental Medicine. 189: 159-168. PMID 9874572 DOI: 10.1084/Jem.189.1.159 |
0.372 |
|
| 1999 |
Novobrantseva TI, Martin VM, Pelanda R, Müller W, Rajewsky K, Ehlich A. Rearrangement and expression of immunoglobulin light chain genes can precede heavy chain expression during normal B cell development in mice Journal of Experimental Medicine. 189: 75-87. PMID 9874565 DOI: 10.1084/Jem.189.1.75 |
0.443 |
|
| 1999 |
Bräuninger A, Küppers R, Spieker T, Siebert R, Strickler JG, Schlegelberger B, Rajewsky K, Hansmann M. Molecular Analysis of Single B Cells From T-Cell–Rich B-Cell Lymphoma Shows the Derivation of the Tumor Cells From Mutating Germinal Center B Cells and Exemplifies Means by Which Immunoglobulin Genes Are Modified in Germinal Center B Cells Blood. 93: 2679-2687. DOI: 10.1182/Blood.V93.8.2679.408K05_2679_2687 |
0.485 |
|
| 1999 |
Bräuninger A, Küppers R, Spieker T, Siebert R, Strickler JG, Schlegelberger B, Rajewsky K, Hansmann M. Molecular Analysis of Single B Cells From T-Cell–Rich B-Cell Lymphoma Shows the Derivation of the Tumor Cells From Mutating Germinal Center B Cells and Exemplifies Means by Which Immunoglobulin Genes Are Modified in Germinal Center B Cells Blood. 93: 2679-2687. DOI: 10.1182/blood.V93.8.2679 |
0.384 |
|
| 1998 |
Klein U, Rajewsky K, Küppers R. Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. The Journal of Experimental Medicine. 188: 1679-89. PMID 9802980 DOI: 10.1084/Jem.188.9.1679 |
0.485 |
|
| 1998 |
Lam KP, Rajewsky K. Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 13171-5. PMID 9789060 DOI: 10.1073/Pnas.95.22.13171 |
0.501 |
|
| 1998 |
Pasqualucci L, Migliazza A, Fracchiolla N, William C, Neri A, Baldini L, Chaganti RS, Klein U, Küppers R, Rajewsky K, Dalla-Favera R. BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci. Proceedings of the National Academy of Sciences of the United States of America. 95: 11816-21. PMID 9751748 DOI: 10.1073/Pnas.95.20.11816 |
0.451 |
|
| 1998 |
Rajewsky K. Burnet's unhappy hybrid. Nature. 394: 624-5. PMID 9716126 DOI: 10.1038/29187 |
0.307 |
|
| 1998 |
Roers A, Montesinos-Rongen M, Hansmann ML, Rajewsky K, Küppers R. Amplification of TCRbeta gene rearrangements from micromanipulated single cells: T cells rosetting around Hodgkin and Reed-Sternberg cells in Hodgkin's disease are polyclonal. European Journal of Immunology. 28: 2424-31. PMID 9710220 DOI: 10.1002/(Sici)1521-4141(199808)28:08<2424::Aid-Immu2424>3.0.Co;2-R |
0.436 |
|
| 1998 |
Irsch J, Nitsch S, Hansmann ML, Rajewsky K, Tesch H, Diehl V, Jox A, Küppers R, Radbruch A. Isolation of viable Hodgkin and Reed-Sternberg cells from Hodgkin disease tissues. Proceedings of the National Academy of Sciences of the United States of America. 95: 10117-22. PMID 9707610 DOI: 10.1073/Pnas.95.17.10117 |
0.526 |
|
| 1998 |
Fukita Y, Jacobs H, Rajewsky K. Somatic hypermutation in the heavy chain locus correlates with transcription. Immunity. 9: 105-14. PMID 9697840 DOI: 10.1016/S1074-7613(00)80592-0 |
0.383 |
|
| 1998 |
Fehr T, Rickert RC, Odermatt B, Roes J, Rajewsky K, Hengartner H, Zinkernagel RM. Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19. The Journal of Experimental Medicine. 188: 145-55. PMID 9653091 DOI: 10.1084/Jem.188.1.145 |
0.418 |
|
| 1998 |
Chan VW, Mecklenbräuker I, Su I, Texido G, Leitges M, Carsetti R, Lowell CA, Rajewsky K, Miyake K, Tarakhovsky A. The molecular mechanism of B cell activation by toll-like receptor protein RP-105. The Journal of Experimental Medicine. 188: 93-101. PMID 9653087 DOI: 10.1084/Jem.188.1.93 |
0.379 |
|
| 1998 |
Manis JP, Gu Y, Lansford R, Sonoda E, Ferrini R, Davidson L, Rajewsky K, Alt FW. Ku70 is required for late B cell development and immunoglobulin heavy chain class switching. The Journal of Experimental Medicine. 187: 2081-9. PMID 9625768 DOI: 10.1084/Jem.187.12.2081 |
0.469 |
|
| 1998 |
Jacobs H, Fukita Y, van der Horst GT, de Boer J, Weeda G, Essers J, de Wind N, Engelward BP, Samson L, Verbeek S, de Murcia JM, de Murcia G, te Riele H, Rajewsky K. Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice. The Journal of Experimental Medicine. 187: 1735-43. PMID 9607915 DOI: 10.1084/Jem.187.11.1735 |
0.351 |
|
| 1998 |
Klein U, Goossens T, Fischer M, Kanzler H, Braeuninger A, Rajewsky K, Küppers R. Somatic hypermutation in normal and transformed human B cells. Immunological Reviews. 162: 261-80. PMID 9602370 DOI: 10.1111/J.1600-065X.1998.Tb01447.X |
0.518 |
|
| 1998 |
Küppers R, Rajewsky K. The origin of Hodgkin and Reed/Sternberg cells in Hodgkin's disease. Annual Review of Immunology. 16: 471-93. PMID 9597138 DOI: 10.1146/Annurev.Immunol.16.1.471 |
0.482 |
|
| 1998 |
Lansford R, Manis JP, Sonoda E, Rajewsky K, Alt FW. Ig heavy chain class switching in Rag-deficient mice. International Immunology. 10: 325-32. PMID 9576620 DOI: 10.1093/Intimm/10.3.325 |
0.48 |
|
| 1998 |
Casellas R, Nussenzweig A, Wuerffel R, Pelanda R, Reichlin A, Suh H, Qin XF, Besmer E, Kenter A, Rajewsky K, Nussenzweig MC. Ku80 is required for immunoglobulin isotype switching Embo Journal. 17: 2404-2411. PMID 9545251 DOI: 10.1093/Emboj/17.8.2404 |
0.444 |
|
| 1998 |
Clausen BE, Waldburger JM, Schwenk F, Barras E, Mach B, Rajewsky K, Förster I, Reith W. Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice. Immunity. 8: 143-55. PMID 9491996 DOI: 10.1016/S1074-7613(00)80467-7 |
0.409 |
|
| 1998 |
Schwenk F, Kuhn R, Angrand PO, Rajewsky K, Stewart AF. Temporally and spatially regulated somatic mutagenesis in mice. Nucleic Acids Research. 26: 1427-32. PMID 9490788 DOI: 10.1093/Nar/26.6.1427 |
0.43 |
|
| 1998 |
Küppers R, Hansmann ML, Diehl V, Rajewsky K. Molecular single-cell analysis of Hodgkin and Reed-Sternberg cells. Molecular Medicine Today. 1: 26-30. PMID 9415134 DOI: 10.1016/1357-4310(95)80016-6 |
0.404 |
|
| 1997 |
Pelanda R, Schwers S, Sonoda E, Torres RM, Nemazee D, Rajewsky K. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 7: 765-75. PMID 9430222 DOI: 10.1016/S1074-7613(00)80395-7 |
0.496 |
|
| 1997 |
Schwenk F, Sauer B, Kukoc N, Hoess R, Müller W, Kocks C, Kühn R, Rajewsky K. Generation of Cre recombinase-specific monoclonal antibodies, able to characterize the pattern of Cre expression in cre-transgenic mouse strains. Journal of Immunological Methods. 207: 203-12. PMID 9368647 DOI: 10.1016/S0022-1759(97)00116-6 |
0.441 |
|
| 1997 |
Papavasiliou F, Casellas R, Suh H, Qin XF, Besmer E, Pelanda R, Nemazee D, Rajewsky K, Nussenzweig MC. V(D)J recombination in mature B cells: a mechanism for altering antibody responses. Science (New York, N.Y.). 278: 298-301. PMID 9323210 DOI: 10.1126/Science.278.5336.298 |
0.461 |
|
| 1997 |
Lam KP, Kühn R, Rajewsky K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell. 90: 1073-83. PMID 9323135 DOI: 10.1016/S0092-8674(00)80373-6 |
0.519 |
|
| 1997 |
Braeuninger A, Küppers R, Strickler JG, Wacker HH, Rajewsky K, Hansmann ML. Hodgkin and Reed-Sternberg cells in lymphocyte predominant Hodgkin disease represent clonal populations of germinal center-derived tumor B cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 9337-42. PMID 9256483 DOI: 10.1073/Pnas.94.17.9337 |
0.43 |
|
| 1997 |
Alimzhanov MB, Kuprash DV, Kosco-Vilbois MH, Luz A, Turetskaya RL, Tarakhovsky A, Rajewsky K, Nedospasov SA, Pfeffer K. Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 9302-7. PMID 9256477 DOI: 10.1073/Pnas.94.17.9302 |
0.383 |
|
| 1997 |
Küppers R, Rajewsky K, Hansmann ML. Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression. European Journal of Immunology. 27: 1398-405. PMID 9209491 DOI: 10.1002/Eji.1830270616 |
0.441 |
|
| 1997 |
Kaisho T, Schwenk F, Rajewsky K. The roles of gamma 1 heavy chain membrane expression and cytoplasmic tail in IgG1 responses. Science (New York, N.Y.). 276: 412-5. PMID 9103199 DOI: 10.1126/Science.276.5311.412 |
0.401 |
|
| 1997 |
Rickert RC, Roes J, Rajewsky K. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Research. 25: 1317-8. PMID 9092650 DOI: 10.1093/Nar/25.6.1317 |
0.441 |
|
| 1997 |
Sonoda E, Pewzner-Jung Y, Schwers S, Taki S, Jung S, Eilat D, Rajewsky K. B cell development under the condition of allelic inclusion. Immunity. 6: 225-33. PMID 9075923 DOI: 10.1016/S1074-7613(00)80325-8 |
0.621 |
|
| 1997 |
Huetz F, Tornberg UC, Malanchère E, Roes J, Carlsson L, Coutinho A, Holmberg D, Rajewsky K. Targeted disruption of the V(H) 81X gene: influence on the B cell repertoire. European Journal of Immunology. 27: 307-14. PMID 9022033 DOI: 10.1002/Eji.1830270144 |
0.415 |
|
| 1997 |
Betz UA, Vosshenrich CA, Rajewsky K, Müller W. Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination. Current Biology : Cb. 6: 1307-16. PMID 8939573 DOI: 10.1016/S0960-9822(02)70717-3 |
0.424 |
|
| 1997 |
Klein U, Küppers R, Rajewsky K. Evidence for a Large Compartment of IgM-Expressing Memory B Cells in Humans Blood. 89: 1288-1298. DOI: 10.1182/Blood.V89.4.1288 |
0.506 |
|
| 1997 |
Rajewsky K, Kanzler H, Hansmann M, Küppers R. Normal and malignant B-cell development with special reference to Hodgkin's disease Annals of Oncology. 8: S79-S81. DOI: 10.1093/Annonc/8.Suppl_2.S79 |
0.489 |
|
| 1997 |
Roers A, Küppers R, Hansmann M, Rajewsky K. T cells rosetting around the tumor cells in Hodgkin's disease: Analysis of TCR gene rearrangements by single cell PCR Immunology Letters. 56: 361. DOI: 10.1016/S0165-2478(97)86460-7 |
0.395 |
|
| 1997 |
Nedospasov S, Alimzhanov M, Kuprash D, Turetskaya R, Drize N, Chertkov J, Tarakhovsky A, Rajewsky K, Pfeffer K. Generation and characterization of mice with a targeted deletion of the entire TNF/lymphotoxin locus (TNFα, LTα, LTβ) employing CRE-loxP mediated recombination Immunology Letters. 56: 352-353. DOI: 10.1016/S0165-2478(97)86427-9 |
0.315 |
|
| 1997 |
Schmedt C, Niidome T, Rajewsky K, Aizawa S, Tarakhovsky A. Conditional inactivation of the Csk gene during T cell development Immunology Letters. 56: 350. DOI: 10.1016/S0165-2478(97)86417-6 |
0.359 |
|
| 1997 |
Kanzler H, Küppers R, Helmes S, Hansmann M, Rajewsky K. The origin of the Hodgkin and Reed-Sternberg (HRS) cells in Hodgkin's disease and their relationship to HRS-like cells occuring in B-cell chronic lymphatic leukemia Immunology Letters. 56: 325. DOI: 10.1016/S0165-2478(97)86313-4 |
0.41 |
|
| 1997 |
Schwenk F, Angrand P, Kühn R, Stewart A, Rajewsky K. Ligand inducible, B cell-specific gene targeting in mice Immunology Letters. 56: 93. DOI: 10.1016/S0165-2478(97)85365-5 |
0.434 |
|
| 1997 |
Clausen B, Reith W, Mach B, Rajewsky K, Förster I. Cell type-specific ablation of MHC class II expression on subsets of antigen presenting cells by CRE/LOXP-mediated deletion of RFX5 Immunology Letters. 56: 5. DOI: 10.1016/S0165-2478(97)85017-1 |
0.393 |
|
| 1996 |
Morawetz RA, Gabriele L, Rizzo LV, Noben-Trauth N, Kühn R, Rajewsky K, Müller W, Doherty TM, Finkelman F, Coffman RL, Morse HC. Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse. The Journal of Experimental Medicine. 184: 1651-61. PMID 8920855 DOI: 10.1084/Jem.184.5.1651 |
0.318 |
|
| 1996 |
Kanzler H, Küppers R, Hansmann ML, Rajewsky K. Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. The Journal of Experimental Medicine. 184: 1495-505. PMID 8879220 DOI: 10.1084/Jem.184.4.1495 |
0.462 |
|
| 1996 |
Küppers R, Kanzler H, Hansmann ML, Rajewsky K. Single cell analysis of Hodgkin/Reed-Sternberg cells. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 27-30. PMID 8836405 DOI: 10.1093/Annonc/7.Suppl_4.S27 |
0.44 |
|
| 1996 |
Bründler MA, Aichele P, Bachmann M, Kitamura D, Rajewsky K, Zinkernagel RM. Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory. European Journal of Immunology. 26: 2257-62. PMID 8814275 DOI: 10.1002/Eji.1830260943 |
0.417 |
|
| 1996 |
Pelanda R, Schaal S, Torres RM, Rajewsky K. A prematurely expressed Igκ transgene, but not a VκJκ gene segment targeted into the Igκ locus, can rescue B cell development in λ5-deficient mice Immunity. 5: 229-239. PMID 8808678 DOI: 10.1016/S1074-7613(00)80318-0 |
0.448 |
|
| 1996 |
Texidó G, Jacobs H, Meiering M, Kühn R, Roes J, Müller W, Gilfillan S, Fujiwara H, Kikutani H, Yoshida N, Amakawa R, Benoist C, Mathis D, Kishimoto T, Mak TW, ... Rajewsky K, et al. Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants. European Journal of Immunology. 26: 1966-9. PMID 8765046 DOI: 10.1002/Eji.1830260843 |
0.378 |
|
| 1996 |
Küppers R, Hajadi M, Plank L, Rajewsky K, Hansmann M. Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enhancers) abolishes somatic hypermutation in the human. European Journal of Immunology. 26: 1794-1800. PMID 8765023 DOI: 10.1002/Eji.1830260820 |
0.461 |
|
| 1996 |
Rajewsky K. Clonal selection and learning in the antibody system. Nature. 381: 751-8. PMID 8657279 DOI: 10.1038/381751A0 |
0.445 |
|
| 1996 |
Torres RM, Flaswinkel H, Reth M, Rajewsky K. Aberrant B cell development and immune response in mice with a compromised BCR complex Science. 272: 1804-1808. PMID 8650582 DOI: 10.1126/Science.272.5269.1804 |
0.482 |
|
| 1996 |
Löffert D, Ehlich A, Müller W, Rajewsky K. Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development. Immunity. 4: 133-44. PMID 8624804 DOI: 10.1016/S1074-7613(00)80678-0 |
0.486 |
|
| 1996 |
Ferradini L, Gu H, De Smet A, Rajewsky K, Reynaud CA, Weill JC. Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster. Science (New York, N.Y.). 271: 1416-20. PMID 8596914 DOI: 10.1126/Science.271.5254.1416 |
0.324 |
|
| 1996 |
Schwenk F, Baron U, Rajewsky K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Research. 23: 5080-1. PMID 8559668 DOI: 10.1093/Nar/23.24.5080 |
0.361 |
|
| 1996 |
Kanzler H, Hansmann M, Kapp U, Wolf J, Diehl V, Rajewsky K, Kuppers R. Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed- Sternberg cells of a Hodgkin's lymphoma patient Blood. 87: 3429-3436. DOI: 10.1182/Blood.V87.8.3429.Bloodjournal8783429 |
0.395 |
|
| 1995 |
Christoph T, Rickert R, Rajewsky K. M17: a novel gene expressed in germinal centers. International Immunology. 6: 1203-11. PMID 7981148 DOI: 10.1093/Intimm/6.8.1203 |
0.454 |
|
| 1995 |
von der Weid T, Kitamura D, Rajewsky K, Langhorne J. A dual role for B cells in Plasmodium chabaudi chabaudi (AS) infection? Research in Immunology. 145: 412-9. PMID 7899705 DOI: 10.1016/S0923-2494(94)80170-3 |
0.421 |
|
| 1995 |
Smith KG, Weiss U, Rajewsky K, Nossal GJ, Tarlinton DM. Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers. Immunity. 1: 803-13. PMID 7895168 DOI: 10.1016/S1074-7613(94)80022-7 |
0.48 |
|
| 1995 |
DiSanto JP, Müller W, Guy-Grand D, Fischer A, Rajewsky K. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain. Proceedings of the National Academy of Sciences of the United States of America. 92: 377-81. PMID 7831294 DOI: 10.1073/Pnas.92.2.377 |
0.352 |
|
| 1995 |
Zou YR, Müller W, Gu H, Rajewsky K. Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies. Current Biology : Cb. 4: 1099-103. PMID 7704573 DOI: 10.1016/S0960-9822(00)00248-7 |
0.374 |
|
| 1995 |
Tarakhovsky A, Turner M, Schaal S, Mee PJ, Duddy LP, Rajewsky K, Tybulewicz VL. Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. Nature. 374: 467-70. PMID 7700358 DOI: 10.1038/374467A0 |
0.495 |
|
| 1995 |
Kühn R, Schwenk F, Aguet M, Rajewsky K. Inducible gene targeting in mice. Science (New York, N.Y.). 269: 1427-9. PMID 7660125 DOI: 10.1126/Science.7660125 |
0.337 |
|
| 1995 |
Taki S, Schwenk F, Rajewsky K. Rearrangement of upstream DH and VH genes to a rearranged immunoglobulin variable region gene inserted into the DQ52-JH region of the immunoglobulin heavy chain locus. European Journal of Immunology. 25: 1888-96. PMID 7621865 DOI: 10.1002/Eji.1830250715 |
0.457 |
|
| 1995 |
Roes J, Müller W, Rajewsky K. Mouse anti-mouse IgD monoclonal antibodies generated in IgD-deficient mice. Journal of Immunological Methods. 183: 231-7. PMID 7602146 DOI: 10.1016/0022-1759(95)00059-J |
0.397 |
|
| 1995 |
Rickert RC, Rajewsky K, Roes J. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Nature. 376: 352-5. PMID 7543183 DOI: 10.1038/376352A0 |
0.476 |
|
| 1995 |
Tarakhovsky A, Kanner SB, Hombach J, Ledbetter JA, Müller W, Killeen N, Rajewsky K. A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science (New York, N.Y.). 269: 535-7. PMID 7542801 DOI: 10.1126/Science.7542801 |
0.37 |
|
| 1995 |
Küppers R, Rajewsky K, Zhao M, Simons G, Laumann R, Fischer R, Hansmann ML. Hodgkin's disease: clonal Ig gene rearrangements in Hodgkin and Reed-Sternberg cells picked from histological sections. Annals of the New York Academy of Sciences. 764: 523-4. PMID 7486580 DOI: 10.1111/J.1749-6632.1995.Tb55877.X |
0.343 |
|
| 1995 |
Klein U, Klein G, Ehlin-Henriksson B, Rajewsky K, Küppers R. Burkitt’s Lymphoma Is a Malignancy of Mature B Cells Expressing Somatically Mutated V Region Genes Molecular Medicine. 1: 495-505. DOI: 10.1007/Bf03401587 |
0.467 |
|
| 1994 |
Müller W, Rajewsky K, Kühn R. Interleukin-4-deficient mice. Research in Immunology. 144: 637-8. PMID 8303082 DOI: 10.1016/S0923-2494(05)80018-5 |
0.394 |
|
| 1994 |
Klein U, Küppers R, Rajewsky K. Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life. European Journal of Immunology. 23: 3272-7. PMID 8258343 DOI: 10.1002/Eji.1830231232 |
0.489 |
|
| 1994 |
Wagner SD, Williams GT, Larson T, Neuberger MS, Kitamura D, Rajewsky K, Xian J, Brüggemann M. Antibodies generated from human immunoglobulin miniloci in transgenic mice. Nucleic Acids Research. 22: 1389-93. PMID 8190629 DOI: 10.1093/Nar/22.8.1389 |
0.654 |
|
| 1994 |
Beutner U, Kraus E, Kitamura D, Rajewsky K, Huber BT. B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens. The Journal of Experimental Medicine. 179: 1457-66. PMID 8163931 DOI: 10.1084/Jem.179.5.1457 |
0.473 |
|
| 1994 |
Schmitz J, Thiel A, Kühn R, Rajewsky K, Müller W, Assenmacher M, Radbruch A. Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells. The Journal of Experimental Medicine. 179: 1349-53. PMID 8145047 DOI: 10.1084/Jem.179.4.1349 |
0.511 |
|
| 1994 |
Fehling HJ, Swat W, Laplace C, Kühn R, Rajewsky K, Müller U, von Boehmer H. MHC class I expression in mice lacking the proteasome subunit LMP-7. Science (New York, N.Y.). 265: 1234-7. PMID 8066463 DOI: 10.1126/Science.8066463 |
0.35 |
|
| 1994 |
Löffert D, Schaal S, Ehlich A, Hardy RR, Zou YR, Müller W, Rajewsky K. Early B-cell development in the mouse: insights from mutations introduced by gene targeting. Immunological Reviews. 137: 135-53. PMID 8034332 DOI: 10.1111/J.1600-065X.1994.Tb00662.X |
0.426 |
|
| 1994 |
Gu H, Marth JD, Orban PC, Mossmann H, Rajewsky K. Deletion of a DNA polymerase β gene segment in T cells using cell type- specific gene targeting Science. 265: 103-106. PMID 8016642 DOI: 10.1126/Science.8016642 |
0.384 |
|
| 1994 |
Küppers R, Rajewsky K, Zhao M, Simons G, Laumann R, Fischer R, Hansmann ML. Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development. Proceedings of the National Academy of Sciences of the United States of America. 91: 10962-6. PMID 7971992 DOI: 10.1073/Pnas.91.23.10962 |
0.474 |
|
| 1994 |
Ehlich A, Martin V, Müller W, Rajewsky K. Analysis of the B-cell progenitor compartment at the level of single cells. Current Biology : Cb. 4: 573-83. PMID 7953531 DOI: 10.1016/S0960-9822(00)00129-9 |
0.459 |
|
| 1994 |
Klein U, Küppers R, Rajewsky K. Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age. The Journal of Experimental Medicine. 180: 1383-93. PMID 7931072 DOI: 10.1084/Jem.180.4.1383 |
0.495 |
|
| 1994 |
Tarakhovsky A, Müller W, Rajewsky K. Lymphocyte populations and immune responses in CD5-deficient mice. European Journal of Immunology. 24: 1678-84. PMID 7517879 DOI: 10.1002/Eji.1830240733 |
0.452 |
|
| 1994 |
Sadlack B, Kühn R, Schorle H, Rajewsky K, Müller W, Horak I. Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4. European Journal of Immunology. 24: 281-4. PMID 7517363 DOI: 10.1002/Eji.1830240144 |
0.304 |
|
| 1993 |
Ehlich A, Schaal S, Gu H, Kitamura D, Müller W, Rajewsky K. Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development. Cell. 72: 695-704. PMID 8453664 DOI: 10.1016/0092-8674(93)90398-A |
0.467 |
|
| 1993 |
Rajewsky K. B-cell lifespans in the mouse--why to debate what? Immunology Today. 14: 40-1; discussion 41-. PMID 8442863 DOI: 10.1016/0167-5699(93)90324-E |
0.474 |
|
| 1993 |
Jung S, Rajewsky K, Radbruch A. Shutdown of class switch recombination by deletion of a switch region control element. Science (New York, N.Y.). 259: 984-7. PMID 8438159 DOI: 10.1126/Science.8438159 |
0.613 |
|
| 1993 |
Roes J, Rajewsky K. Immunoglobulin D (IgD)-deficient mice reveal an auxiliary receptor function for IgD in antigen-mediated recruitment of B cells. The Journal of Experimental Medicine. 177: 45-55. PMID 8418208 DOI: 10.1084/Jem.177.1.45 |
0.521 |
|
| 1993 |
Kühn R, Löhler J, Rennick D, Rajewsky K, Müller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 75: 263-74. PMID 8402911 DOI: 10.1016/0092-8674(93)80068-P |
0.369 |
|
| 1993 |
Zou YR, Gu H, Rajewsky K. Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions. Science (New York, N.Y.). 262: 1271-4. PMID 8235658 DOI: 10.1126/Science.8235658 |
0.37 |
|
| 1993 |
Taki S, Meiering M, Rajewsky K. Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus. Science (New York, N.Y.). 262: 1268-71. PMID 8235657 DOI: 10.1126/Science.8235657 |
0.425 |
|
| 1993 |
Küppers R, Fischer U, Rajewsky K, Gause A. Immunoglobulin heavy and light chain gene sequences of a human CD5 positive immunocytoma and sequences of four novel VHIII germline genes. Immunology Letters. 34: 57-62. PMID 1282498 DOI: 10.1016/0165-2478(92)90027-L |
0.34 |
|
| 1993 |
Küppers R, Zhao M, Hansmann M, Rajewsky K. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections. The Embo Journal. 12: 4955-4967. DOI: 10.1002/J.1460-2075.1993.Tb06189.X |
0.49 |
|
| 1993 |
Zou Y, Takeda S, Rajewsky K. Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa. The Embo Journal. 12: 811-820. DOI: 10.1002/J.1460-2075.1993.Tb05721.X |
0.497 |
|
| 1992 |
Roes J, Rajewsky K. Cell autonomous expression of IgD is not essential for the maturation of conventional B cells. International Immunology. 3: 1367-71. PMID 1838007 DOI: 10.1093/Intimm/3.12.1367 |
0.525 |
|
| 1992 |
Rajewsky K. Early and late B-cell development in the mouse. Current Opinion in Immunology. 4: 171-6. PMID 1605906 DOI: 10.1016/0952-7915(92)90008-3 |
0.478 |
|
| 1992 |
Kitamura D, Kudo A, Schaal S, Müller W, Melchers F, Rajewsky K. A critical role of λ5 protein in B cell development Cell. 69: 823-831. PMID 1591779 DOI: 10.1016/0092-8674(92)90293-L |
0.516 |
|
| 1992 |
Kitamura D, Rajewsky K. Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion. Nature. 356: 154-6. PMID 1545868 DOI: 10.1038/356154A0 |
0.425 |
|
| 1992 |
Tarlinton D, Förster I, Rajewsky K. An explanation for the defect in secretion of IgM Mott cells and their predominant occurrence in the Ly-1 B cell compartment. European Journal of Immunology. 22: 531-9. PMID 1537387 DOI: 10.1002/Eji.1830220236 |
0.497 |
|
| 1992 |
Weiss U, Zoebelein R, Rajewsky K. Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen. European Journal of Immunology. 22: 511-7. PMID 1537385 DOI: 10.1002/Eji.1830220233 |
0.384 |
|
| 1992 |
Gu H, Förster I, Rajewsky K. Study of murine B-cell development through analysis of immunoglobulin variable region genes. Annals of the New York Academy of Sciences. 651: 304-10. PMID 1534647 DOI: 10.1111/J.1749-6632.1992.Tb24628.X |
0.441 |
|
| 1992 |
Schittek B, Rajewsky K. Natural occurrence and origin of somatically mutated memory B cells in mice. The Journal of Experimental Medicine. 176: 427-38. PMID 1500855 DOI: 10.1084/Jem.176.2.427 |
0.532 |
|
| 1992 |
Simon T, Rajewsky K. A functional antibody mutant with an insertion in the framework region 3 loop of the VH domain: implications for antibody engineering. Protein Engineering. 5: 229-34. PMID 1409542 DOI: 10.1093/Protein/5.3.229 |
0.354 |
|
| 1992 |
Taki S, Schmitt M, Tarlinton D, Förster I, Rajewsky K. T cell-dependent antibody production by Ly-1 B cells. Annals of the New York Academy of Sciences. 651: 328-35. PMID 1376052 DOI: 10.1111/J.1749-6632.1992.Tb24632.X |
0.484 |
|
| 1992 |
Rajewsky K. Early and late B-cell development in the mouse Current Biology. 2: 307. DOI: 10.1016/0960-9822(92)90879-F |
0.434 |
|
| 1991 |
Förster I, Vieira P, Rajewsky K. Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse. International Immunology. 1: 321-31. PMID 2518724 DOI: 10.1093/Intimm/1.4.321 |
0.471 |
|
| 1991 |
Vieira P, Rajewsky K. Persistence of memory B cells in mice deprived of T cell help. International Immunology. 2: 487-94. PMID 2150759 DOI: 10.1093/Intimm/2.6.487 |
0.457 |
|
| 1991 |
Sumida T, Maeda T, Koike T, Tomioka H, Yoshida S, Taniguchi M, Rajewsky K. Expression of IgH promoter/enhancer Ly-1 transgene in hematopoietic chimeric mice generated by embryonic stem cell line. International Archives of Allergy and Applied Immunology. 93: 155-64. PMID 2129165 DOI: 10.1159/000235295 |
0.486 |
|
| 1991 |
Weiss U, Rajewsky K. The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response. The Journal of Experimental Medicine. 172: 1681-9. PMID 2124253 DOI: 10.1084/Jem.172.6.1681 |
0.461 |
|
| 1991 |
Müller W, Kühn R, Rajewsky K. Major histocompatibility complex class II hyperexpression on B cells in interleukin 4-transgenic mice does not lead to B cell proliferation and hypergammaglobulinemia. European Journal of Immunology. 21: 921-5. PMID 2019289 DOI: 10.1002/Eji.1830210410 |
0.471 |
|
| 1991 |
Gu H, Kitamura D, Rajewsky K. B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames. Cell. 65: 47-54. PMID 2013094 DOI: 10.1016/0092-8674(91)90406-O |
0.385 |
|
| 1991 |
Schittek B, Rajewsky K, Förster I. Dividing cells in bone marrow and spleen incorporate bromodeoxyuridine with high efficiency. European Journal of Immunology. 21: 235-8. PMID 1991489 DOI: 10.1002/Eji.1830210136 |
0.373 |
|
| 1991 |
Jacob J, Kelsoe G, Rajewsky K, Weiss U. Intraclonal generation of antibody mutants in germinal centres Nature. 354: 389-392. PMID 1956400 DOI: 10.1038/354389A0 |
0.75 |
|
| 1991 |
Kühn R, Rajewsky K, Müller W. Generation and analysis of interleukin-4 deficient mice. Science (New York, N.Y.). 254: 707-10. PMID 1948049 DOI: 10.1126/Science.1948049 |
0.395 |
|
| 1991 |
Gu H, Tarlinton D, Müller W, Rajewsky K, Förster I. Most peripheral B cells in mice are ligand selected. The Journal of Experimental Medicine. 173: 1357-71. PMID 1903427 DOI: 10.1084/Jem.173.6.1357 |
0.509 |
|
| 1991 |
Kitamura D, Roes J, Kühn R, Rajewsky K. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature. 350: 423-6. PMID 1901381 DOI: 10.1038/350423A0 |
0.485 |
|
| 1991 |
Förster I, Müller W, Schittek B, Rajewsky K. Generation of long-lived B cells in germ-free mice. European Journal of Immunology. 21: 1779-82. PMID 1829417 DOI: 10.1002/Eji.1830210732 |
0.473 |
|
| 1991 |
Förster I, Gu H, Müller W, Schmitt M, Tarlinton D, Rajewsky K. CD5 B cells in the mouse. Current Topics in Microbiology and Immunology. 173: 247-51. PMID 1717201 DOI: 10.1007/978-3-642-76492-9_35 |
0.455 |
|
| 1991 |
Küppers R, Gause A, Rajewsky K. B cells of chronic lymphatic leukemia express V genes in unmutated form. Leukemia Research. 15: 487-96. PMID 1713635 DOI: 10.1016/0145-2126(91)90060-7 |
0.415 |
|
| 1990 |
Rajewsky K, Gu H, Vieira P, Förster I. Growth and selection of B cells in vivo. Cold Spring Harbor Symposia On Quantitative Biology. 209-17. PMID 2639754 DOI: 10.1101/Sqb.1989.054.01.026 |
0.388 |
|
| 1990 |
Schittek B, Rajewsky K. Maintenance of B-cell memory by long-lived cells generated from proliferating precursors. Nature. 346: 749-51. PMID 2388695 DOI: 10.1038/346749A0 |
0.396 |
|
| 1990 |
Förster I, Rajewsky K. The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 87: 4781-4. PMID 2352948 DOI: 10.1073/Pnas.87.12.4781 |
0.452 |
|
| 1990 |
Simon T, Rajewsky K. Antibody domain mutants demonstrate autonomy of the antigen binding site. The Embo Journal. 9: 1051-1056. DOI: 10.1002/J.1460-2075.1990.Tb08209.X |
0.313 |
|
| 1990 |
Gu H, Förster I, Rajewsky K. Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation. The Embo Journal. 9: 2133-2140. DOI: 10.1002/J.1460-2075.1990.Tb07382.X |
0.429 |
|
| 1989 |
Allen D, Cumano A, Simon T, Sablitzky F, Rajewsky K. Modulation of antibody binding affinity by somatic mutation. International Journal of Cancer. Supplement = Journal International Du Cancer. Supplement. 3: 1-8. PMID 3264819 DOI: 10.1002/Ijc.2910410802 |
0.346 |
|
| 1989 |
Müller W, Rüther U, Vieira P, Hombach J, Reth M, Rajewsky K. Membrane-bound IgM obstructs B cell development in transgenic mice. European Journal of Immunology. 19: 923-8. PMID 2786813 DOI: 10.1002/Eji.1830190520 |
0.485 |
|
| 1989 |
Kocks C, Rajewsky K. Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways. Annual Review of Immunology. 7: 537-59. PMID 2653375 DOI: 10.1146/Annurev.Iy.07.040189.002541 |
0.406 |
|
| 1989 |
Belyavsky A, Vinogradova T, Rajewsky K. PCR-based cDNA library construction: general cDNA libraries at the level of a few cells. Nucleic Acids Research. 17: 2919-32. PMID 2471144 DOI: 10.1093/Nar/17.8.2919 |
0.31 |
|
| 1988 |
Kocks C, Rajewsky K. Stepwise intraclonal maturation of antibody affinity through somatic hypermutation. Proceedings of the National Academy of Sciences of the United States of America. 85: 8206-10. PMID 3263647 DOI: 10.1073/Pnas.85.21.8206 |
0.418 |
|
| 1988 |
Hombach J, Sablitzky F, Rajewsky K, Reth M. Transfected plasmacytoma cells do not transport the membrane form of IgM to the cell surface. The Journal of Experimental Medicine. 167: 652-7. PMID 3258011 DOI: 10.1084/Jem.167.2.652 |
0.438 |
|
| 1988 |
Rüther U, Müller W, Sumida T, Tokuhisa T, Rajewsky K, Wagner EF. c-fos expression interferes with thymus development in transgenic mice. Cell. 53: 847-56. PMID 3133119 DOI: 10.1016/S0092-8674(88)90289-9 |
0.415 |
|
| 1988 |
Simon T, Rajewsky K. 'Enhancer-constitutive' vectors for the expression of recombinant antibodies. Nucleic Acids Research. 16: 354. PMID 2829122 DOI: 10.1093/Nar/16.1.354 |
0.328 |
|
| 1988 |
Förster I, Gu H, Rajewsky K. Germline antibody V regions as determinants of clonal persistence and malignant growth in the B cell compartment. The Embo Journal. 7: 3693-3703. DOI: 10.1002/J.1460-2075.1988.Tb03251.X |
0.532 |
|
| 1988 |
Hombach J, Leclercq L, Radbruch A, Rajewsky K, Reth M. A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells. The Embo Journal. 7: 3451-3456. DOI: 10.1002/J.1460-2075.1988.Tb03219.X |
0.586 |
|
| 1988 |
Allen D, Simon T, Sablitzky F, Rajewsky K, Cumano A. Antibody engineering for the analysis of affinity maturation of an anti-hapten response. The Embo Journal. 7: 1995-2001. DOI: 10.1002/J.1460-2075.1988.Tb03038.X |
0.372 |
|
| 1987 |
Gause A, Yoshida N, Kappen C, Rajewsky K. In vivo generation and function of B cells in the presence of a monoclonal anti-IgM antibody: implications for B cell tolerance. European Journal of Immunology. 17: 981-90. PMID 3497044 DOI: 10.1002/Eji.1830170714 |
0.512 |
|
| 1987 |
Siekevitz M, Kocks C, Rajewsky K, Dildrop R. Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses. Cell. 48: 757-70. PMID 3493076 DOI: 10.1016/0092-8674(87)90073-0 |
0.444 |
|
| 1987 |
Rajewsky K, Förster I, Cumano A. Evolutionary and somatic selection of the antibody repertoire in the mouse. Science (New York, N.Y.). 238: 1088-94. PMID 3317826 DOI: 10.1126/Science.3317826 |
0.468 |
|
| 1987 |
Allen D, Cumano A, Dildrop R, Kocks C, Rajewsky K, Rajewsky N, Roes J, Sablitzky F, Siekevitz M. Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development. Immunological Reviews. 96: 5-22. PMID 3298009 DOI: 10.1111/J.1600-065X.1987.Tb00506.X |
0.412 |
|
| 1987 |
Saito T, Tokuhisa T, Rajewsky K. Induction of chronic idiotype suppression by ligands binding to the variable (not the constant) region of the idiotypic target. European Journal of Immunology. 16: 1419-25. PMID 3096746 DOI: 10.1002/Eji.1830161117 |
0.396 |
|
| 1987 |
Dildrop R, Gause A, Müller W, Rajewsky K. A new V gene expressed in lambda-2 light chains of the mouse. European Journal of Immunology. 17: 731-4. PMID 3034625 DOI: 10.1002/Eji.1830170525 |
0.36 |
|
| 1987 |
Förster I, Rajewsky K. Expansion and functional activity of Ly-1+ B cells upon transfer of peritoneal cells into allotype-congenic, newborn mice. European Journal of Immunology. 17: 521-8. PMID 2436924 DOI: 10.1002/Eji.1830170414 |
0.478 |
|
| 1987 |
Yoshida N, Radbruch A, Rajewsky K. Ig gene rearrangement and expression in the progeny of B-cell progenitors in the course of clonal expansion in bone marrow cultures. The Embo Journal. 6: 2735-2741. DOI: 10.1002/J.1460-2075.1987.Tb02567.X |
0.606 |
|
| 1986 |
Rajewsky K, Takemori T. Genetics, expression, and function of idiotypes. Annual Review of Immunology. 1: 569-607. PMID 6399979 DOI: 10.1146/Annurev.Iy.01.040183.003033 |
0.427 |
|
| 1986 |
Dildrop R, Krawinkel U, Winter E, Rajewsky K. VH-gene expression in murine lipopolysaccharide blasts distributes over the nine known VH-gene groups and may be random. European Journal of Immunology. 15: 1154-6. PMID 3933987 DOI: 10.1002/Eji.1830151117 |
0.327 |
|
| 1986 |
Vieira P, Rajewsky K. The bulk of endogenously produced IgG2a is eliminated from the serum of adult C57BL/6 mice with a half-life of 6-8 days. European Journal of Immunology. 16: 871-4. PMID 3487461 DOI: 10.1002/Eji.1830160727 |
0.301 |
|
| 1986 |
Radbruch A, Müller W, Rajewsky K. Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts. Proceedings of the National Academy of Sciences of the United States of America. 83: 3954-7. PMID 3086872 DOI: 10.1073/Pnas.83.11.3954 |
0.6 |
|
| 1986 |
Steplewski Z, Spira G, Blaszczyk M, Lubeck MD, Radbruch A, Illges H, Herlyn D, Rajewsky K, Scharff M. Isolation and characterization of anti-monosialoganglioside monoclonal antibody 19-9 class-switch variants. Proceedings of the National Academy of Sciences of the United States of America. 82: 8653-7. PMID 2934735 DOI: 10.1073/Pnas.82.24.8653 |
0.478 |
|
| 1985 |
Karmann G, Beyreuther KT, Cramer M, Holtkamp B, Proksa S, Rajewsky K. A structural somatic variant of the Kk antigen is generated by point mutation. Immunogenetics. 22: 35-48. PMID 4018852 DOI: 10.1007/Bf00430592 |
0.403 |
|
| 1985 |
Weichel W, Liesegang B, Gehrke K, Göttlinger C, Holtkamp B, Radbruch A, Stackhouse TK, Rajewsky K. Inexpensive upgrading of a FACS I and isolation of rare somatic variants by double-fluorescence sorting. Cytometry. 6: 116-23. PMID 3979216 DOI: 10.1002/Cyto.990060206 |
0.478 |
|
| 1985 |
Smith FI, Cumano A, Licht A, Pecht I, Rajewsky K. Low affinity of kappa chain bearing (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific antibodies in the primary antibody repertoire of C57BL/6 mice may explain lambda chain dominance in primary anti-NP responses. Molecular Immunology. 22: 1209-16. PMID 3935916 DOI: 10.1016/0161-5890(85)90010-0 |
0.336 |
|
| 1985 |
Cumano A, Rajewsky K. Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice. European Journal of Immunology. 15: 512-20. PMID 3873342 DOI: 10.1002/Eji.1830150517 |
0.399 |
|
| 1985 |
Tokuhisa T, Rajewsky K. Antigen induces chronic idiotype suppression. Proceedings of the National Academy of Sciences of the United States of America. 82: 4217-20. PMID 3159020 DOI: 10.1073/Pnas.82.12.4217 |
0.415 |
|
| 1985 |
Saito T, Rajewsky K. Helper T cells reacting to idiotype on IgG but not IgM. The Journal of Experimental Medicine. 162: 1399-404. PMID 2931497 DOI: 10.1084/Jem.162.4.1399 |
0.39 |
|
| 1985 |
Radbruch A, Zaiss S, Kappen C, Brüggemann M, Beyreuther K, Rajewsky K. Drastic change in idiotypic but not antigen-binding specificity of an antibody by a single amino-acid substitution. Nature. 315: 506-8. PMID 2582273 DOI: 10.1038/315506A0 |
0.551 |
|
| 1985 |
Saito T, Rajewsky K. A self-Ia reactive T cell clone directly stimulates every hundredth B cell and helps antigen-specific B cell responses. European Journal of Immunology. 15: 927-34. PMID 2412837 DOI: 10.1002/Eji.1830150912 |
0.472 |
|
| 1985 |
Sablitzky F, Weisbaum D, Rajewsky K. Sequence analysis of non-expressed immunoglobulin heavy chain loci in clonally related, somatically mutated hybridoma cells. The Embo Journal. 4: 3435-3437. DOI: 10.1002/J.1460-2075.1985.Tb04101.X |
0.419 |
|
| 1985 |
Sablitzky F, Wildner G, Rajewsky K. Somatic mutation and clonal expansion of B cells in an antigen-driven immune response. The Embo Journal. 4: 345-350. DOI: 10.1002/J.1460-2075.1985.Tb03635.X |
0.477 |
|
| 1984 |
Müller CE, Rajewsky K. Idiotope regulation by isotype switch variants of two monoclonal antiidiotope antibodies. The Journal of Experimental Medicine. 159: 758-72. PMID 6699544 DOI: 10.1084/jem.159.3.758 |
0.313 |
|
| 1984 |
Takemori T, Rajewsky K. Specificity, duration and mechanism of idiotype suppression induced by neonatal injection of monoclonal anti-idiotope antibodies into mice. European Journal of Immunology. 14: 656-67. PMID 6611268 DOI: 10.1002/Eji.1830140714 |
0.51 |
|
| 1984 |
Rajnavölgyi E, Reth M, Uher F, Miklós K, Gergely J, Rajewsky K. Fc-dependent effector functions of idiotype-anti-idiotype immune complexes. Molecular Immunology. 21: 127-36. PMID 6608663 DOI: 10.1016/0161-5890(84)90127-5 |
0.37 |
|
| 1984 |
Takemori T, Rajewsky K. Mechanism of neonatally induced idiotype suppression and its relevance for the acquisition of self-tolerance. Immunological Reviews. 79: 103-17. PMID 6378762 DOI: 10.1111/J.1600-065X.1984.Tb00489.X |
0.439 |
|
| 1984 |
Smith FI, Tesch H, Rajewsky K. Heterogeneous and monoclonal helper T cells induce similar anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibody populations in the primary adoptive response. II. Lambda light chain dominance and idiotope expression. European Journal of Immunology. 14: 195-200. PMID 6230245 DOI: 10.1002/Eji.1830140216 |
0.335 |
|
| 1984 |
Tesch H, Smith FI, Müller-Hermes WJ, Rajewsky K. Heterogeneous and monoclonal helper T cells induce similar anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibody populations in the primary adoptive response. I. Isotype distribution. European Journal of Immunology. 14: 188-94. PMID 6199216 DOI: 10.1002/Eji.1830140215 |
0.423 |
|
| 1984 |
Vohr HW, Holtkamp B, Rajewsky K. Somatic H-2Kk variants reveal nonidentity of serological and cytotoxic T cell-defined Kk determinants. European Journal of Immunology. 13: 846-51. PMID 6196205 DOI: 10.1002/Eji.1830131012 |
0.442 |
|
| 1984 |
RADBRUCH A, SABLITZKY F, RAJEWSKY K. Isotype switching in myeloma and hybridoma cells compared with LPS blasts Biochemical Society Transactions. 12: 737-737. DOI: 10.1042/Bst0120737 |
0.483 |
|
| 1984 |
Sablitzky F, Rajewsky K. Molecular basis of an isogeneic anti-idiotypic response. The Embo Journal. 3: 3005-3012. DOI: 10.1002/J.1460-2075.1984.Tb02247.X |
0.401 |
|
| 1984 |
Dildrop R, Bovens J, Siekevitz M, Beyreuther K, Rajewsky K. A V region determinant (idiotope) expressed at high frequency in B lymphocytes is encoded by a large set of antibody structural genes. The Embo Journal. 3: 517-523. DOI: 10.1002/J.1460-2075.1984.Tb01840.X |
0.465 |
|
| 1983 |
Takemori T, Tesch H, Reth M, Rajewsky K. The immune response against anti-idiotope antibodies. I. Induction of idiotope-bearing antibodies and analysis of the idiotope repertoire. European Journal of Immunology. 12: 1040-6. PMID 6984391 DOI: 10.1002/Eji.1830121210 |
0.386 |
|
| 1983 |
Radbruch A, Brüggemann M, Liesegang B, Rajewsky K. Isolation of immunoglobulin class-switch and variable-region variants from mouse myeloma and hybridoma cell lines. Advances in Experimental Medicine and Biology. 158: 93-105. PMID 6818850 DOI: 10.1007/978-1-4899-5292-9_11 |
0.444 |
|
| 1983 |
Brüggemann M, Rajewsky K. Regulation of the antibody response against hapten-coupled erythrocytes by monoclonal antihapten antibodies of various isotypes. Cellular Immunology. 71: 365-73. PMID 6754102 DOI: 10.1016/0008-8749(82)90270-2 |
0.348 |
|
| 1983 |
Nishikawa S, Takemori T, Rajewsky K. The expression of a set of antibody variable regions in lipopolysaccharide-reactive B cells at various stages of ontogeny and its control by anti-idiotypic antibody. European Journal of Immunology. 13: 318-25. PMID 6602052 DOI: 10.1002/Eji.1830130409 |
0.496 |
|
| 1983 |
Tesch H, Takemori T, Rajewsky K. The immune response against anti-idiotope antibodies II. The induction of antibodies bearing the target idiotope (Ab3 beta) depends on the frequency of the corresponding B cells. European Journal of Immunology. 13: 726-32. PMID 6413225 DOI: 10.1002/Eji.1830130907 |
0.403 |
|
| 1983 |
Krawinkel U, Zoebelein G, Brüggemann M, Radbruch A, Rajewsky K. Recombination between antibody heavy chain variable-region genes: evidence for gene conversion. Proceedings of the National Academy of Sciences of the United States of America. 80: 4997-5001. PMID 6308665 DOI: 10.1073/Pnas.80.16.4997 |
0.545 |
|
| 1983 |
Rajewsky K. Symmetry and asymmetry in idiotypic interactions. Annales D'Immunologie. 133-41. PMID 6194739 DOI: 10.1016/S0769-2625(83)80064-6 |
0.33 |
|
| 1983 |
Holtkamp B, Cramer M, Rajewsky K. Somatic variation of H-2Kk expression and structure in a T-cell lymphoma: instability, stabilization, high production and structural mutation. The Embo Journal. 2: 1943-1951. DOI: 10.1002/J.1460-2075.1983.Tb01683.X |
0.437 |
|
| 1982 |
Sablitzky F, Radbruch A, Rajewsky K. Spontaneous immunoglobulin class switching in myeloma and hybridoma cell lines differs from physiological class switching. Immunological Reviews. 67: 59-72. PMID 6751996 DOI: 10.1111/J.1600-065X.1982.Tb01055.X |
0.478 |
|
| 1982 |
Bothwell AL, Paskind M, Reth M, Imanishi-Kari T, Rajewsky K, Baltimore D. Somatic variants of murine immunoglobulin lambda light chains. Nature. 298: 380-2. PMID 6283385 DOI: 10.1038/298380A0 |
0.329 |
|
| 1982 |
Dildrop R, Brüggemann M, Radbruch A, Rajewsky K, Beyreuther K. Immunoglobulin V region variants in hybridoma cells. II. Recombination between V genes. The Embo Journal. 1: 635-640. DOI: 10.1002/J.1460-2075.1982.Tb01220.X |
0.551 |
|
| 1982 |
Brüggemann M, Radbruch A, Rajewsky K. Immunoglobulin V region variants in hybridoma cells. I. Isolation of a variant with altered idiotypic and antigen binding specificity. The Embo Journal. 1: 629-634. DOI: 10.1002/J.1460-2075.1982.Tb01219.X |
0.604 |
|
| 1981 |
Neuberger MS, Rajewsky K. Activation of mouse complement by monoclonal mouse antibodies. European Journal of Immunology. 11: 1012-6. PMID 7327198 DOI: 10.1002/Eji.1830111212 |
0.619 |
|
| 1981 |
Holtkamp B, Cramer M, Lemke H, Rajewsky K. Isolation of a cloned cell line expressing variant H-2Kk using fluorescence-activated cell sorting. Nature. 289: 66-8. PMID 7005691 DOI: 10.1038/289066A0 |
0.409 |
|
| 1981 |
Neuberger MS, Rajewsky K. Switch from hapten-specific immunoglobulin M to immunoglobulin D secretion in a hybrid mouse cell line. Proceedings of the National Academy of Sciences of the United States of America. 78: 1138-42. PMID 6940132 DOI: 10.1073/Pnas.78.2.1138 |
0.612 |
|
| 1981 |
Takemori T, Rajewsky K. Lambda chain expression at different stages of ontogeny in C57BL/6, BALB/c and SJL mice. European Journal of Immunology. 11: 618-25. PMID 6791945 DOI: 10.1002/Eji.1830110806 |
0.453 |
|
| 1981 |
Kelsoe G, Reth M, Rajewsky K. Control of idiotype expression by monoclonal anti-idiotope and idiotope-bearing antibody European Journal of Immunology. 11: 418-423. PMID 6790289 DOI: 10.1002/Eji.1830110513 |
0.59 |
|
| 1981 |
Bothwell AL, Paskind M, Reth M, Imanishi-Kari T, Rajewsky K, Baltimore D. Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region. Cell. 24: 625-37. PMID 6788376 DOI: 10.1016/0092-8674(81)90089-1 |
0.377 |
|
| 1981 |
Reth M, Kelsoe G, Rajewsky K. Idiotypic regulation by isologous monoclonal anti-idiotope antibodies Nature. 290: 257-259. PMID 6782489 DOI: 10.1038/290257A0 |
0.567 |
|
| 1980 |
Kelsoe G, Reth M, Rajewsky K. Control idiotope expression by monoclonal anti-idiotope antibodies Immunological Reviews. 52: 75-88. PMID 6790422 DOI: 10.1111/J.1600-065X.1980.Tb00331.X |
0.552 |
|
| 1980 |
Radbruch A, Liesegang B, Rajewsky K. Isolation of variants of mouse myeloma X63 that express changed immunoglobulin class. Proceedings of the National Academy of Sciences of the United States of America. 77: 2909-13. PMID 6771763 DOI: 10.1073/Pnas.77.5.2909 |
0.563 |
|
| 1980 |
Krawinkel U, Cramer M, Kindred B, Rajewsky K. Isolated hapten-binding receptors of sensitized lymphocytes. V. Cellular origin of receptor molecules. European Journal of Immunology. 9: 815-20. PMID 520409 DOI: 10.1002/Eji.1830091013 |
0.433 |
|
| 1980 |
Reth M, Imanishi-Kari T, Rajewsky K. Analysis of the repertoire of anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti-idiotope antibodies. European Journal of Immunology. 9: 1004-13. PMID 398773 DOI: 10.1002/Eji.1830091216 |
0.356 |
|
| 1979 |
Cramer M, Krawinkel U, Melchers I, Imanishi-Kari T, Ben-Neriah Y, Givol D, Rajewsky K. Isolated hapten-binding receptors of sensitized lymphocytes. IV. Expression of immunoglobulin variable regions in (4-hydroxy-3-nitrophenyl) acetyl (NP)-specific receptors isolated from murine B and T lymphocytes. European Journal of Immunology. 9: 332-8. PMID 111953 DOI: 10.1002/Eji.1830090415 |
0.435 |
|
| 1979 |
Imanishi-Kari T, Rajnavölgyi E, Takemori T, Jack RS, Rajewsky K. The effect of light chain gene expression on the inheritance of an idiotype associated with primary anti-(4-hydroxy-3-nitrophenyl)acetyl(NP) antibodies. European Journal of Immunology. 9: 324-31. PMID 89036 DOI: 10.1002/Eji.1830090414 |
0.363 |
|
| 1979 |
Holtkamp B, Lindahl KF, Segall M, Rajewsky K. Spontaneous loss and subsequent stimulation of H-2 expression in clones of a heterozygous lymphoma cell line Immunogenetics. 9: 405-421. DOI: 10.1007/Bf01570434 |
0.367 |
|
| 1978 |
Imanshi-Kari T, Reth M, Hämmerling GJ, Rajewsky K. Analysis of V gene expression in the immune response by cell fusion. Current Topics in Microbiology and Immunology. 81: 20-6. PMID 567558 DOI: 10.1007/978-3-642-67448-8_3 |
0.363 |
|
| 1978 |
Hämmerling GJ, Lemke H, Hämmerling U, Höhmann C, Wallich R, Rajewsky K. Monoclonal antibodies against murine cell surface antigens: anti-H-2, anti-Ia and anti-T cell antibodies. Current Topics in Microbiology and Immunology. 81: 100-6. PMID 567552 DOI: 10.1007/978-3-642-67448-8_15 |
0.406 |
|
| 1978 |
Krawinkel U, Cramer M, Melchers I, Imanishi-Kari T, Rajewsky K. Isolated hapten-binding receptors of sensitized lymphocytes. III. Evidence for idiotypic restriction of T-cell receptors. The Journal of Experimental Medicine. 147: 1341-7. PMID 418137 DOI: 10.1084/Jem.147.5.1341 |
0.411 |
|
| 1978 |
Eichmann K, Falk I, Rajewsky K. Recognition of idiotypes in lymphocyte interactions. II. Antigen-independent cooperation between T and B lymphocytes that possess similar and complementary idiotypes European Journal of Immunology. 8: 853-857. PMID 365546 DOI: 10.1002/Eji.1830081206 |
0.487 |
|
| 1978 |
Liesegang B, Radbruch A, Rajewsky K. Isolation of myeloma variants with predefined variant surface immunoglobulin by cell sorting. Proceedings of the National Academy of Sciences of the United States of America. 75: 3901-5. PMID 308657 DOI: 10.1073/Pnas.75.8.3901 |
0.56 |
|
| 1978 |
Reth M, Hämmerling GJ, Rajewsky K. Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response. European Journal of Immunology. 8: 393-400. PMID 97089 DOI: 10.1002/Eji.1830080605 |
0.378 |
|
| 1978 |
Lemke H, Hammerling GJ, Hohmann C, Rajewsky K. Hybrid cell lines secreting monoclonal antibody specific for major histocompatibility antigens of the mouse. Nature. 271: 249-51. PMID 74805 DOI: 10.1038/271249A0 |
0.398 |
|
| 1977 |
Jack RS, Imanishi-Kari T, Rajewsky K. Idiotypic analysis of the response of C57BL/6 mice to the (4-hydroxy-3-nitrophenyl)acetyl group. European Journal of Immunology. 7: 559-65. PMID 409605 DOI: 10.1002/Eji.1830070813 |
0.336 |
|
| 1977 |
Krawinkel U, Cramer M, Mage RG, Kelus AS, Rajewsky K. Isolated hapten-binding receptors of sensitized lymphocytes. II. Receptors from nylon wool-enriched rabbit T lymphocytes lack serological determinants of immunoglobulin constant domains but carry the A locus allotypic markers. The Journal of Experimental Medicine. 146: 792-801. PMID 408458 DOI: 10.1084/Jem.146.3.792 |
0.369 |
|
| 1977 |
Rajewsky K, Eichmann K. Antigen receptors of T helper cells Contemporary Topics in Immunobiology. 7: 69-112. PMID 69518 DOI: 10.1007/978-1-4684-3054-7_3 |
0.345 |
|
| 1977 |
HÄMMERLING GJ, RETH M, RADBRUCH A, HEWITT J, RAJEWSKY K. Fusion of Myeloma Cells with Mouse Lymphocytes Biochemical Society Transactions. 5: 33-33. DOI: 10.1042/Bst0050033A |
0.581 |
|
| 1976 |
Krawinkel U, Rajewsky K. Specific enrichment of antigen-binding receptors from sensitized murine lymphocytes. European Journal of Immunology. 6: 529-36. PMID 789093 DOI: 10.1002/Eji.1830060802 |
0.381 |
|
| 1976 |
Black SJ, Hammerling GJ, Berek C, Rajewsky K, Eichmann K. Idiotypic analysis of lymphocytes in vitro. I. Specificity and heterogeneity of B and T lymphocytes reactive with anti idiotypic antibody Journal of Experimental Medicine. 143: 846-860. PMID 768405 DOI: 10.1084/Jem.143.4.846 |
0.463 |
|
| 1976 |
Krawinkel U, Cramer M, Berek C, Hämmerling G, Black SJ, Rajewsky K, Eichmann K. On the structure of the T cell receptor for antigen Origins of Lymphocyte Diversity Cold Spring Harbor Symposia On Quantitative Biology. 41: 285-294. PMID 408092 DOI: 10.1101/Sqb.1977.041.01.034 |
0.4 |
|
| 1976 |
Hammerling GJ, Black SJ, Berek C, Eichmann K, Rajewsky K. Idiotypic analysis of lymphocytes in vitro. II. Genetic control of T helper cell responsiveness to anti idiotypic antibody Journal of Experimental Medicine. 143: 861-869. PMID 56419 DOI: 10.1084/Jem.143.4.861 |
0.432 |
|
| 1976 |
Black SJ, HäMMERLING GJ, Eichmann K, Rajewsky K. Idiotypic Identity Of Strep. A Specific Antigen Recognition Sites On Mouse T And B-Lymphocytes Leukocyte Membrane Determinants Regulating Immune Reactivity. 149-160. DOI: 10.1016/B978-0-12-233750-5.50031-2 |
0.437 |
|
| 1975 |
Eichmann K, Rajewsky K. Induction of T and B cell immunity by anti idiotypic antibody European Journal of Immunology. 5: 661-666. PMID 11993330 DOI: 10.1002/Eji.1830051002 |
0.457 |
|
| 1974 |
Melchers I, Rajewsky K, Shreffler DC. Ir-LDHB: map position and functional analysis. European Journal of Immunology. 3: 754-61. PMID 4781392 DOI: 10.1002/Eji.1830031204 |
0.426 |
|
| 1970 |
Schirrmacher V, Rajewsky K. Determination of antibody class in a system of cooperating antigenic determinants. The Journal of Experimental Medicine. 132: 1019-34. PMID 4097133 DOI: 10.1084/Jem.132.5.1019 |
0.344 |
|
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