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Pawel K Mazur, PhD - Publications

Affiliations: 
2005-2011 Max Planck Institut for Medical Research/Technical University of Munich 
 2011-2016 Stanford University, Palo Alto, CA 
 2016- Experimental Radiation Oncology The University of Texas MD Anderson Cancer Center 
Website:
https://faculty.mdanderson.org/profiles/pawel_mazur.html
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lukinovic V, Hausmann S, Roth GS, Oyeniran C, Ahmad T, Tsao N, Brickner JR, Casanova AG, Chuffart F, Morales Benitez A, Vayr J, Rodell R, Tardif M, Jansen PWTC, Coute Y, ... ... Mazur PK, et al. SMYD3 impedes small cell lung cancer sensitivity to alkylation damage through RNF113A methylation-phosphorylation crosstalk. Cancer Discovery. PMID 35819319 DOI: 10.1158/2159-8290.CD-21-0205  0.309
2021 Sengupta D, Zeng L, Li Y, Hausmann S, Ghosh D, Yuan G, Nguyen TN, Lyu R, Caporicci M, Morales Benitez A, Coles GL, Kharchenko V, Czaban I, Azhibek D, Fischle W, ... ... Mazur PK, et al. NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis. Molecular Cell. PMID 34555356 DOI: 10.1016/j.molcel.2021.08.034  0.591
2021 Hester R, Mazur PK, McAllister F. Immunotherapy in Pancreatic Adenocarcinoma: Beyond "Copy / Paste". Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34193514 DOI: 10.1158/1078-0432.CCR-18-0900  0.347
2021 Yuan G, Flores NM, Hausmann S, Lofgren SM, Kharchenko V, Angulo-Ibanez M, Sengupta D, Lu X, Czaban I, Azhibek D, Vicent S, Fischle W, Jaremko M, Fang B, Wistuba II, ... ... Mazur PK, et al. Elevated NSD3 histone methylation activity drives squamous cell lung cancer. Nature. PMID 33536620 DOI: 10.1038/s41586-020-03170-y  0.314
2020 Wang Z, Hausmann S, Lyu R, Li TM, Lofgren SM, Flores NM, Fuentes ME, Caporicci M, Yang Z, Meiners MJ, Cheek MA, Howard SA, Zhang L, Elias JE, Kim MP, ... ... Mazur PK, et al. SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy. Cancer Cell. PMID 32442403 DOI: 10.1016/J.Ccell.2020.04.014  0.589
2019 Valencia K, Erice O, Kostyrko K, Hausmann S, Guruceaga E, Thathireddy A, Flores NM, Sayles LC, Lee AG, Fragoso R, Sun TQ, Vallejo A, Roman M, Entrialgo-Cadierno R, Migueliz I, ... ... Mazur PK, et al. The mir181ab1 cluster promotes kras-driven oncogenesis and progression in lung and pancreas. The Journal of Clinical Investigation. PMID 31874105 DOI: 10.1172/Jci129012  0.446
2018 Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M, Kim MP, Maitra A, ... ... Mazur PK, et al. METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Cell. PMID 30612740 DOI: 10.1016/J.Cell.2018.11.038  0.508
2017 Mello SS, Sinow C, Raj N, Mazur PK, Bieging-Rolett K, Broz DK, Imam JFC, Vogel H, Wood LD, Sage J, Hirose T, Nakagawa S, Rinn J, Attardi LD. Neat1 is a p53-inducible lincRNA essential for transformation suppression. Genes & Development. PMID 28698299 DOI: 10.1101/Gad.284661.116  0.6
2017 Vallejo A, Perurena N, Guruceaga E, Mazur PK, Martinez-Canarias S, Zandueta C, Valencia K, Arricibita A, Gwinn D, Sayles LC, Chuang CH, Guembe L, Bailey P, Chang DK, Biankin A, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nature Communications. 8: 14294. PMID 28220783 DOI: 10.1038/Ncomms14294  0.656
2016 Mazur PK, Gozani O, Sage J, Reynoird N. Novel insights into the oncogenic function of the SMYD3 lysine methyltransferase. Translational Cancer Research. 5: 330-333. PMID 30713830 DOI: 10.21037/Tcr.2016.06.26  0.525
2016 Jahchan NS, Lim JS, Bola B, Morris K, Seitz G, Tran KQ, Xu L, Trapani F, Morrow CJ, Cristea S, Coles GL, Yang D, Vaka D, Kareta MS, George J, ... Mazur PK, et al. Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer. Cell Reports. PMID 27373157 DOI: 10.1016/J.Celrep.2016.06.021  0.615
2016 Krampitz GW, George BM, Willingham SB, Volkmer JP, Weiskopf K, Jahchan N, Newman AM, Sahoo D, Zemek AJ, Yanovsky RL, Nguyen JK, Schnorr PJ, Mazur PK, Sage J, Longacre TA, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035983 DOI: 10.1073/Pnas.1600007113  0.615
2016 Reynoird N, Mazur PK, Stellfeld T, Flores NM, Lofgren SM, Carlson SM, Brambilla E, Hainaut P, Kaznowska EB, Arrowsmith CH, Khatri P, Stresemann C, Gozani O, Sage J. Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer. Genes & Development. PMID 26988419 DOI: 10.1101/Gad.275529.115  0.666
2016 Attardi LD, Mello SS, Valente EJ, Mazur PK, Raj N, Bieging-Rolett K, Vogel H. Abstract PR07: Deconstructing p53 transcriptional networks in pancreatic cancer suppression Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-Pr07  0.369
2016 Mello SS, Sinow C, Mazur PK, Vogel H, Rinn J, Attardi LD. Abstract A45: Neat1 is a p53-inducible lincRNA important for pancreatic cancer suppression Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A45  0.383
2016 Mazur PK, Reynoird N, Stellfeld T, Flores NM, Lofgren SM, Carlson SM, Brambilla E, Hainaut P, Kaznowska EB, Arrowsmith CH, Khatri P, Stresemann C, Gozani O, Sage J. Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A44  0.603
2016 Vallejo A, Perurena N, Guruceaga E, Mazur PK, Martinez-Canarias S, Zandueta C, Gwinn D, Sayles LC, Chuang C, Andersen JB, Bozec A, Sweet-Cordero A, Sage J, Lecanda F, Vicent S. An integrative cross-tumors approach identifies FOSL1 as an oncogene dependency in KRAS-driven lung cancer Journal of Thoracic Oncology. 11: S51. DOI: 10.1016/J.Jtho.2015.12.084  0.572
2015 Mazur PK, Sage J. Pancreatic cancer takes its Toll. The Journal of Experimental Medicine. 212: 1988. PMID 26573583 DOI: 10.1084/Jem.21212Insight1  0.619
2015 Mazur PK, Herner A, Mello SS, Wirth M, Hausmann S, Sánchez-Rivera FJ, Lofgren SM, Kuschma T, Hahn SA, Vangala D, Trajkovic-Arsic M, Gupta A, Heid I, Noël PB, Braren R, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nature Medicine. PMID 26390243 DOI: 10.1038/Nm.3952  0.722
2015 Mazur PK, Herner A, Neff F, Siveke JT. Current methods in mouse models of pancreatic cancer. Methods in Molecular Biology (Clifton, N.J.). 1267: 185-215. PMID 25636470 DOI: 10.1007/978-1-4939-2297-0_9  0.587
2015 Baumgart A, Mazur PK, Anton M, Rudelius M, Schwamborn K, Feuchtinger A, Behnke K, Walch A, Braren R, Peschel C, Duyster J, Siveke JT, Dechow T. Opposing role of Notch1 and Notch2 in a Kras(G12D)-driven murine non-small cell lung cancer model. Oncogene. 34: 578-88. PMID 24509876 DOI: 10.1038/Onc.2013.592  0.585
2015 Reynoird N, Mazur P, Sage J, Gozani O. SMYD3 links lysine methylation of MAP3K2 to ras-driven lung cancer European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa4256  0.629
2015 Hausmann S, Regel I, Federlein A, Mazur PK, Steiger K, Michalski CW, Erkan M, Kleeff J. Abstract B08: The role of periostin in pancreatic carcinogenesis and metastatic spread Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B08  0.522
2015 Mazur PK, Reynoird N, Khatri P, Butte AJ, Wilkinson A, Garcia B, Liu S, Vermeulen M, Jansen PWTC, Tummino PJ, Kruger RG, Aller GSV, Barbash O, Huddleston M, Gozani O, et al. Abstract A23: SMYD3 links methylation of MAP3K2 to Ras-driven tumors Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A23  0.648
2015 Hausmann S, Regel I, Mazur P, Federlein A, Wagner N, Steiger K, Michalski C, Erkan M, Friess H, Kleeff J. Periostin promotes pancreatic carcinogenesis and metastatic spread Pancreatology. 15. DOI: 10.1016/J.Pan.2015.05.145  0.514
2014 Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 510: 283-7. PMID 24847881 DOI: 10.1038/Nature13320  0.628
2014 Chen R, Khatri P, Mazur PK, Polin M, Zheng Y, Vaka D, Hoang CD, Shrager J, Xu Y, Vicent S, Butte AJ, Sweet-Cordero EA. A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma. Cancer Research. 74: 2892-902. PMID 24654231 DOI: 10.1158/0008-5472.Can-13-2775  0.401
2014 Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos A, Vaka D, Tran KQt, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, et al. Abstract 4610: A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors Cancer Research. 74: 4610-4610. DOI: 10.1158/1538-7445.Am2014-4610  0.637
2013 Jahchan NS, Dudley JT, Mazur PK, Flores N, Yang D, Palmerton A, Zmoos AF, Vaka D, Tran KQ, Zhou M, Krasinska K, Riess JW, Neal JW, Khatri P, Park KS, et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discovery. 3: 1364-77. PMID 24078773 DOI: 10.1158/2159-8290.Cd-13-0183  0.62
2013 Jameson KL, Mazur PK, Zehnder AM, Zhang J, Zarnegar B, Sage J, Khavari PA. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors. Nature Medicine. 19: 626-30. PMID 23603816 DOI: 10.1038/Nm.3165  0.595
2013 Kalideris E, Grüner B, Trajkovic-Arsic M, Mazur P, Schmid R, Siveke J. The role of insulin receptor and insulin-like growth factor I receptor in pancreatic ductal adenocarcinoma Zeitschrift Fur Gastroenterologie. 51. DOI: 10.1055/S-0033-1352845  0.415
2012 Ardito CM, Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, Delgiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D, Briel T, Herner A, Trajkovic-Arsic M, Sipos B, et al. EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell. 22: 304-17. PMID 22975374 DOI: 10.1016/J.Ccr.2012.07.024  0.58
2012 Grüner BM, Hahne H, Mazur PK, Trajkovic-Arsic M, Maier S, Esposito I, Kalideris E, Michalski CW, Kleeff J, Rauser S, Schmid RM, Küster B, Walch A, Siveke JT. MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer. Plos One. 7: e39424. PMID 22761793 DOI: 10.1371/Journal.Pone.0039424  0.538
2012 Aichler M, Seiler C, Tost M, Siveke J, Mazur PK, Da Silva-Buttkus P, Bartsch DK, Langer P, Chiblak S, Dürr A, Höfler H, Klöppel G, Müller-Decker K, Brielmeier M, Esposito I. Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues. The Journal of Pathology. 226: 723-34. PMID 21984419 DOI: 10.1002/Path.3017  0.584
2012 Mazur PK, Riener MO, Jochum W, Kristiansen G, Weber A, Schmid RM, Siveke JT. Expression and clinicopathological significance of notch signaling and cell-fate genes in biliary tract cancer. The American Journal of Gastroenterology. 107: 126-35. PMID 21931375 DOI: 10.1038/Ajg.2011.305  0.595
2012 Mazur PK, Siveke JT. Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology. Gut. 61: 1488-500. PMID 21873467 DOI: 10.1136/Gutjnl-2011-300756  0.589
2012 Mazur PK, Lubeseder-Martellato C, Grüner BM, Sipos B, Angelis MHd, Sage J, Schmid RM, Siveke JT. Abstract A55: Dual role of the Notch ligand Delta-1 in pancreatic carcinogenesis and metastasis. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A55  0.724
2011 Viatour P, Ehmer U, Saddic LA, Dorrell C, Andersen JB, Lin C, Zmoos AF, Mazur PK, Schaffer BE, Ostermeier A, Vogel H, Sylvester KG, Thorgeirsson SS, Grompe M, Sage J. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. The Journal of Experimental Medicine. 208: 1963-76. PMID 21875955 DOI: 10.1084/Jem.20110198  0.567
2011 Heid I, Lubeseder-Martellato C, Sipos B, Mazur PK, Lesina M, Schmid RM, Siveke JT. Early requirement of Rac1 in a mouse model of pancreatic cancer. Gastroenterology. 141: 719-30, 730.e1-7. PMID 21684285 DOI: 10.1053/J.Gastro.2011.04.043  0.63
2011 Mazur PK, Lubeseder-Martellato C, Grüner BM, Kaznowska E, Sipos B, Angelis MHd, Schmid RM, Sage J, Siveke JT. Abstract PR16: Important bidirectional function in the Notch-Delta signaling in pancreatic carcinogenesis and metastasis Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Pr16  0.731
2011 Grüner BM, Lubeseder-Martellato C, Briel T, Mazur PK, Schmid RM, Siveke JT. Abstract PR11: Egfr is essential for Ras-driven pancreatic cancer development Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Pr11  0.604
2011 Brodylo RL, Lee M, Lubeseder-Martellato C, Mazur PK, Hampel F, Zimber-Strobel U, Strobel LJ, Schmid RM, Siveke JT. Abstract A32: Notch pathway regulates pancreatic acinar-to-ductal metaplasia Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A32  0.597
2010 Mazur PK, Grüner BM, Nakhai H, Sipos B, Zimber-Strobl U, Strobl LJ, Radtke F, Schmid RM, Siveke JT. Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo. Plos One. 5: e13578. PMID 21042537 DOI: 10.1371/Journal.Pone.0013578  0.593
2010 Mazur PK, Einwächter H, Lee M, Sipos B, Nakhai H, Rad R, Zimber-Strobl U, Strobl LJ, Radtke F, Klöppel G, Schmid RM, Siveke JT. Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 107: 13438-43. PMID 20624967 DOI: 10.1073/Pnas.1002423107  0.666
2010 Grüner B, Hahne H, Trajkovic-Arsic M, Mazur P, Esposito I, Rauser S, Schmid R, Küster B, Walch A, Siveke J. In situ proteomic analysis of preneoplastic lesions in targeted mouse models of pancreatic cancer using MALDI imaging mass spectrometry Zeitschrift Fur Gastroenterologie. 48: 557. DOI: 10.1055/S-0030-1263997  0.498
2010 Mazur P, Sipos B, Zimber-Strobl U, Strobl L, Radtke F, Schmid R, Siveke J. 858 Deficiency of Notch2 suppresses pancreatic carcinogenesis and Myc signaling in vivo European Journal of Cancer Supplements. 8: 216. DOI: 10.1016/S1359-6349(10)71652-9  0.543
2008 Geisler F, Nagl F, Mazur PK, Lee M, Zimber-Strobl U, Strobl LJ, Radtke F, Schmid RM, Siveke JT. Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology (Baltimore, Md.). 48: 607-16. PMID 18666240 DOI: 10.1002/Hep.22381  0.533
2008 Nakhai H, Siveke JT, Klein B, Mendoza-Torres L, Mazur PK, Algül H, Radtke F, Strobl L, Zimber-Strobl U, Schmid RM. Conditional ablation of Notch signaling in pancreatic development. Development (Cambridge, England). 135: 2757-65. PMID 18635610 DOI: 10.1242/Dev.013722  0.598
2008 Siveke JT, Lubeseder-Martellato C, Lee M, Mazur PK, Nakhai H, Radtke F, Schmid RM. Notch signaling is required for exocrine regeneration after acute pancreatitis. Gastroenterology. 134: 544-55. PMID 18242220 DOI: 10.1053/J.Gastro.2007.11.003  0.575
2008 Siveke J, Mazur P, Sipos B, Nakhai H, Radtke F, Strobl L, Zimber-Strobl U, Klöppel G, Schmid R. Pancreas-specific ablation of Notch2 but not Notch1 compromises KrasG12D-induced PanIN progression and tumor development Zeitschrift Fur Gastroenterologie. 46. DOI: 10.1055/S-0028-1089536  0.507
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